data_9ARY
# 
_entry.id   9ARY 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9ARY         pdb_00009ary 10.2210/pdb9ary/pdb 
WWPDB D_1000281825 ?            ?                   
EMDB  EMD-43798    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-02 ? 
2 'EM metadata'     1 0 2025-04-02 ? 
3 'Half map'        1 0 2025-04-02 1 
4 'Half map'        1 0 2025-04-02 2 
5 Image             1 0 2025-04-02 ? 
6 Mask              1 0 2025-04-02 ? 
7 'Primary map'     1 0 2025-04-02 ? 
8 'Structure model' 1 1 2025-05-28 ? 
9 'EM metadata'     1 1 2025-05-28 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 Mask              repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'      
2 9 'EM metadata'     'Data processing'      
3 9 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' em_admin    
2 8 'Structure model' em_software 
3 9 'EM metadata'     em_admin    
4 9 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 8 'Structure model' '_em_admin.last_update' 
2 8 'Structure model' '_em_software.name'     
3 9 'EM metadata'     '_em_admin.last_update' 
4 9 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9ARY 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-24 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        
;Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
_pdbx_database_related.db_id          EMD-43798 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              bryan_roth@med.unc.edu 
_pdbx_contact_author.name_first         Bryan 
_pdbx_contact_author.name_last          Roth 
_pdbx_contact_author.name_mi            L. 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0561-6520 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gumpper, R.H.' 1 ? 
'Fay, J.F.'     2 ? 
'Roth, B.L.'    3 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            16 
_citation.language                  ? 
_citation.page_first                2734 
_citation.page_last                 2734 
_citation.title                     'The structural diversity of psychedelic drug actions revealed.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-025-57956-7 
_citation.pdbx_database_id_PubMed   40108183 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gumpper, R.H.'  1  0000-0003-1309-3069 
primary 'Jain, M.K.'     2  0000-0001-8173-3326 
primary 'Kim, K.'        3  ?                   
primary 'Sun, R.'        4  ?                   
primary 'Sun, N.'        5  ?                   
primary 'Xu, Z.'         6  ?                   
primary 'DiBerto, J.F.'  7  ?                   
primary 'Krumm, B.E.'    8  0000-0001-6039-4767 
primary 'Kapolka, N.J.'  9  ?                   
primary 'Kaniskan, H.U.' 10 0000-0001-5327-832X 
primary 'Nichols, D.E.'  11 ?                   
primary 'Jin, J.'        12 0000-0002-2387-3862 
primary 'Fay, J.F.'      13 0000-0003-1822-2384 
primary 'Roth, B.L.'     14 0000-0002-0561-6520 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '5-hydroxytryptamine receptor 2A'                                   52648.945 1 ? ? ? ? 
2 polymer     man 'G subunit q (Gi2-mini-Gq chimeric)'                                28084.832 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'  39418.086 1 ? ? ? ? 
4 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' 7861.143  1 ? ? ? ? 
5 polymer     man 'single chain Fab (svFv16)'                                         28668.922 1 ? ? ? ? 
6 non-polymer syn SEROTONIN                                                           176.215   1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 '5-HT-2,5-HT-2A,Serotonin receptor 2A' 
3 'Transducin beta chain 1'              
4 'G gamma-I'                            
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
A ? 
2 'polypeptide(L)' no no 
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
;MGSTVSAEDKAAAERSKMIDKNLREDGEKARRTLRLLLLGADNSGKSTIVKQMRILHGGSGGSGGTSGIFETKFQVDKVN
FHMFDVGGQRDERRKWIQCFNDVTAIIFVVDSSDYNRLQEALNDFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKI
EDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRKEFVDISTASGDGRHICYPHFTCAVDTENARRIFNDCKDIILQMNL
REYNLV
;
B ? 
3 'polypeptide(L)' no no 
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
C ? 
4 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL D ? 
5 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
E ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        SEROTONIN 
_pdbx_entity_nonpoly.comp_id     SRO 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ASP n 
1 3   ILE n 
1 4   LEU n 
1 5   CYS n 
1 6   GLU n 
1 7   GLU n 
1 8   ASN n 
1 9   THR n 
1 10  SER n 
1 11  LEU n 
1 12  SER n 
1 13  SER n 
1 14  THR n 
1 15  THR n 
1 16  ASN n 
1 17  SER n 
1 18  LEU n 
1 19  MET n 
1 20  GLN n 
1 21  LEU n 
1 22  ASN n 
1 23  ASP n 
1 24  ASP n 
1 25  THR n 
1 26  ARG n 
1 27  LEU n 
1 28  TYR n 
1 29  SER n 
1 30  ASN n 
1 31  ASP n 
1 32  PHE n 
1 33  ASN n 
1 34  SER n 
1 35  GLY n 
1 36  GLU n 
1 37  ALA n 
1 38  ASN n 
1 39  THR n 
1 40  SER n 
1 41  ASP n 
1 42  ALA n 
1 43  PHE n 
1 44  ASN n 
1 45  TRP n 
1 46  THR n 
1 47  VAL n 
1 48  ASP n 
1 49  SER n 
1 50  GLU n 
1 51  ASN n 
1 52  ARG n 
1 53  THR n 
1 54  ASN n 
1 55  LEU n 
1 56  SER n 
1 57  CYS n 
1 58  GLU n 
1 59  GLY n 
1 60  CYS n 
1 61  LEU n 
1 62  SER n 
1 63  PRO n 
1 64  SER n 
1 65  CYS n 
1 66  LEU n 
1 67  SER n 
1 68  LEU n 
1 69  LEU n 
1 70  HIS n 
1 71  LEU n 
1 72  GLN n 
1 73  GLU n 
1 74  LYS n 
1 75  ASN n 
1 76  TRP n 
1 77  SER n 
1 78  ALA n 
1 79  LEU n 
1 80  LEU n 
1 81  THR n 
1 82  ALA n 
1 83  VAL n 
1 84  VAL n 
1 85  ILE n 
1 86  ILE n 
1 87  LEU n 
1 88  THR n 
1 89  ILE n 
1 90  ALA n 
1 91  GLY n 
1 92  ASN n 
1 93  ILE n 
1 94  LEU n 
1 95  VAL n 
1 96  ILE n 
1 97  MET n 
1 98  ALA n 
1 99  VAL n 
1 100 SER n 
1 101 LEU n 
1 102 GLU n 
1 103 LYS n 
1 104 LYS n 
1 105 LEU n 
1 106 GLN n 
1 107 ASN n 
1 108 ALA n 
1 109 THR n 
1 110 ASN n 
1 111 TYR n 
1 112 PHE n 
1 113 LEU n 
1 114 MET n 
1 115 SER n 
1 116 LEU n 
1 117 ALA n 
1 118 ILE n 
1 119 ALA n 
1 120 ASP n 
1 121 MET n 
1 122 LEU n 
1 123 LEU n 
1 124 GLY n 
1 125 PHE n 
1 126 LEU n 
1 127 VAL n 
1 128 MET n 
1 129 PRO n 
1 130 VAL n 
1 131 SER n 
1 132 MET n 
1 133 LEU n 
1 134 THR n 
1 135 ILE n 
1 136 LEU n 
1 137 TYR n 
1 138 GLY n 
1 139 TYR n 
1 140 ARG n 
1 141 TRP n 
1 142 PRO n 
1 143 LEU n 
1 144 PRO n 
1 145 SER n 
1 146 LYS n 
1 147 LEU n 
1 148 CYS n 
1 149 ALA n 
1 150 VAL n 
1 151 TRP n 
1 152 ILE n 
1 153 TYR n 
1 154 LEU n 
1 155 ASP n 
1 156 VAL n 
1 157 LEU n 
1 158 PHE n 
1 159 SER n 
1 160 THR n 
1 161 ALA n 
1 162 SER n 
1 163 ILE n 
1 164 MET n 
1 165 HIS n 
1 166 LEU n 
1 167 CYS n 
1 168 ALA n 
1 169 ILE n 
1 170 SER n 
1 171 LEU n 
1 172 ASP n 
1 173 ARG n 
1 174 TYR n 
1 175 VAL n 
1 176 ALA n 
1 177 ILE n 
1 178 GLN n 
1 179 ASN n 
1 180 PRO n 
1 181 ILE n 
1 182 HIS n 
1 183 HIS n 
1 184 SER n 
1 185 ARG n 
1 186 PHE n 
1 187 ASN n 
1 188 SER n 
1 189 ARG n 
1 190 THR n 
1 191 LYS n 
1 192 ALA n 
1 193 PHE n 
1 194 LEU n 
1 195 LYS n 
1 196 ILE n 
1 197 ILE n 
1 198 ALA n 
1 199 VAL n 
1 200 TRP n 
1 201 THR n 
1 202 ILE n 
1 203 SER n 
1 204 VAL n 
1 205 GLY n 
1 206 ILE n 
1 207 SER n 
1 208 MET n 
1 209 PRO n 
1 210 ILE n 
1 211 PRO n 
1 212 VAL n 
1 213 PHE n 
1 214 GLY n 
1 215 LEU n 
1 216 GLN n 
1 217 ASP n 
1 218 ASP n 
1 219 SER n 
1 220 LYS n 
1 221 VAL n 
1 222 PHE n 
1 223 LYS n 
1 224 GLU n 
1 225 GLY n 
1 226 SER n 
1 227 CYS n 
1 228 LEU n 
1 229 LEU n 
1 230 ALA n 
1 231 ASP n 
1 232 ASP n 
1 233 ASN n 
1 234 PHE n 
1 235 VAL n 
1 236 LEU n 
1 237 ILE n 
1 238 GLY n 
1 239 SER n 
1 240 PHE n 
1 241 VAL n 
1 242 SER n 
1 243 PHE n 
1 244 PHE n 
1 245 ILE n 
1 246 PRO n 
1 247 LEU n 
1 248 THR n 
1 249 ILE n 
1 250 MET n 
1 251 VAL n 
1 252 ILE n 
1 253 THR n 
1 254 TYR n 
1 255 PHE n 
1 256 LEU n 
1 257 THR n 
1 258 ILE n 
1 259 LYS n 
1 260 SER n 
1 261 LEU n 
1 262 GLN n 
1 263 LYS n 
1 264 GLU n 
1 265 ALA n 
1 266 THR n 
1 267 LEU n 
1 268 CYS n 
1 269 VAL n 
1 270 SER n 
1 271 ASP n 
1 272 LEU n 
1 273 GLY n 
1 274 THR n 
1 275 ARG n 
1 276 ALA n 
1 277 LYS n 
1 278 LEU n 
1 279 ALA n 
1 280 SER n 
1 281 PHE n 
1 282 SER n 
1 283 PHE n 
1 284 LEU n 
1 285 PRO n 
1 286 GLN n 
1 287 SER n 
1 288 SER n 
1 289 LEU n 
1 290 SER n 
1 291 SER n 
1 292 GLU n 
1 293 LYS n 
1 294 LEU n 
1 295 PHE n 
1 296 GLN n 
1 297 ARG n 
1 298 SER n 
1 299 ILE n 
1 300 HIS n 
1 301 ARG n 
1 302 GLU n 
1 303 PRO n 
1 304 GLY n 
1 305 SER n 
1 306 TYR n 
1 307 THR n 
1 308 GLY n 
1 309 ARG n 
1 310 ARG n 
1 311 THR n 
1 312 MET n 
1 313 GLN n 
1 314 SER n 
1 315 ILE n 
1 316 SER n 
1 317 ASN n 
1 318 GLU n 
1 319 GLN n 
1 320 LYS n 
1 321 ALA n 
1 322 CYS n 
1 323 LYS n 
1 324 VAL n 
1 325 LEU n 
1 326 GLY n 
1 327 ILE n 
1 328 VAL n 
1 329 PHE n 
1 330 PHE n 
1 331 LEU n 
1 332 PHE n 
1 333 VAL n 
1 334 VAL n 
1 335 MET n 
1 336 TRP n 
1 337 CYS n 
1 338 PRO n 
1 339 PHE n 
1 340 PHE n 
1 341 ILE n 
1 342 THR n 
1 343 ASN n 
1 344 ILE n 
1 345 MET n 
1 346 ALA n 
1 347 VAL n 
1 348 ILE n 
1 349 CYS n 
1 350 LYS n 
1 351 GLU n 
1 352 SER n 
1 353 CYS n 
1 354 ASN n 
1 355 GLU n 
1 356 ASP n 
1 357 VAL n 
1 358 ILE n 
1 359 GLY n 
1 360 ALA n 
1 361 LEU n 
1 362 LEU n 
1 363 ASN n 
1 364 VAL n 
1 365 PHE n 
1 366 VAL n 
1 367 TRP n 
1 368 ILE n 
1 369 GLY n 
1 370 TYR n 
1 371 LEU n 
1 372 SER n 
1 373 SER n 
1 374 ALA n 
1 375 VAL n 
1 376 ASN n 
1 377 PRO n 
1 378 LEU n 
1 379 VAL n 
1 380 TYR n 
1 381 THR n 
1 382 LEU n 
1 383 PHE n 
1 384 ASN n 
1 385 LYS n 
1 386 THR n 
1 387 TYR n 
1 388 ARG n 
1 389 SER n 
1 390 ALA n 
1 391 PHE n 
1 392 SER n 
1 393 ARG n 
1 394 TYR n 
1 395 ILE n 
1 396 GLN n 
1 397 CYS n 
1 398 GLN n 
1 399 TYR n 
1 400 LYS n 
1 401 GLU n 
1 402 ASN n 
1 403 LYS n 
1 404 LYS n 
1 405 PRO n 
1 406 LEU n 
1 407 GLN n 
1 408 LEU n 
1 409 ILE n 
1 410 LEU n 
1 411 VAL n 
1 412 ASN n 
1 413 THR n 
1 414 ILE n 
1 415 PRO n 
1 416 ALA n 
1 417 LEU n 
1 418 ALA n 
1 419 TYR n 
1 420 LYS n 
1 421 SER n 
1 422 SER n 
1 423 GLN n 
1 424 LEU n 
1 425 GLN n 
1 426 MET n 
1 427 GLY n 
1 428 GLN n 
1 429 LYS n 
1 430 LYS n 
1 431 ASN n 
1 432 SER n 
1 433 LYS n 
1 434 GLN n 
1 435 ASP n 
1 436 ALA n 
1 437 LYS n 
1 438 THR n 
1 439 THR n 
1 440 ASP n 
1 441 ASN n 
1 442 ASP n 
1 443 CYS n 
1 444 SER n 
1 445 MET n 
1 446 VAL n 
1 447 ALA n 
1 448 LEU n 
1 449 GLY n 
1 450 LYS n 
1 451 GLN n 
1 452 HIS n 
1 453 SER n 
1 454 GLU n 
1 455 GLU n 
1 456 ALA n 
1 457 SER n 
1 458 LYS n 
1 459 ASP n 
1 460 ASN n 
1 461 SER n 
1 462 ASP n 
1 463 GLY n 
1 464 VAL n 
1 465 ASN n 
1 466 GLU n 
1 467 LYS n 
1 468 VAL n 
1 469 SER n 
1 470 CYS n 
1 471 VAL n 
2 1   MET n 
2 2   GLY n 
2 3   SER n 
2 4   THR n 
2 5   VAL n 
2 6   SER n 
2 7   ALA n 
2 8   GLU n 
2 9   ASP n 
2 10  LYS n 
2 11  ALA n 
2 12  ALA n 
2 13  ALA n 
2 14  GLU n 
2 15  ARG n 
2 16  SER n 
2 17  LYS n 
2 18  MET n 
2 19  ILE n 
2 20  ASP n 
2 21  LYS n 
2 22  ASN n 
2 23  LEU n 
2 24  ARG n 
2 25  GLU n 
2 26  ASP n 
2 27  GLY n 
2 28  GLU n 
2 29  LYS n 
2 30  ALA n 
2 31  ARG n 
2 32  ARG n 
2 33  THR n 
2 34  LEU n 
2 35  ARG n 
2 36  LEU n 
2 37  LEU n 
2 38  LEU n 
2 39  LEU n 
2 40  GLY n 
2 41  ALA n 
2 42  ASP n 
2 43  ASN n 
2 44  SER n 
2 45  GLY n 
2 46  LYS n 
2 47  SER n 
2 48  THR n 
2 49  ILE n 
2 50  VAL n 
2 51  LYS n 
2 52  GLN n 
2 53  MET n 
2 54  ARG n 
2 55  ILE n 
2 56  LEU n 
2 57  HIS n 
2 58  GLY n 
2 59  GLY n 
2 60  SER n 
2 61  GLY n 
2 62  GLY n 
2 63  SER n 
2 64  GLY n 
2 65  GLY n 
2 66  THR n 
2 67  SER n 
2 68  GLY n 
2 69  ILE n 
2 70  PHE n 
2 71  GLU n 
2 72  THR n 
2 73  LYS n 
2 74  PHE n 
2 75  GLN n 
2 76  VAL n 
2 77  ASP n 
2 78  LYS n 
2 79  VAL n 
2 80  ASN n 
2 81  PHE n 
2 82  HIS n 
2 83  MET n 
2 84  PHE n 
2 85  ASP n 
2 86  VAL n 
2 87  GLY n 
2 88  GLY n 
2 89  GLN n 
2 90  ARG n 
2 91  ASP n 
2 92  GLU n 
2 93  ARG n 
2 94  ARG n 
2 95  LYS n 
2 96  TRP n 
2 97  ILE n 
2 98  GLN n 
2 99  CYS n 
2 100 PHE n 
2 101 ASN n 
2 102 ASP n 
2 103 VAL n 
2 104 THR n 
2 105 ALA n 
2 106 ILE n 
2 107 ILE n 
2 108 PHE n 
2 109 VAL n 
2 110 VAL n 
2 111 ASP n 
2 112 SER n 
2 113 SER n 
2 114 ASP n 
2 115 TYR n 
2 116 ASN n 
2 117 ARG n 
2 118 LEU n 
2 119 GLN n 
2 120 GLU n 
2 121 ALA n 
2 122 LEU n 
2 123 ASN n 
2 124 ASP n 
2 125 PHE n 
2 126 LYS n 
2 127 SER n 
2 128 ILE n 
2 129 TRP n 
2 130 ASN n 
2 131 ASN n 
2 132 ARG n 
2 133 TRP n 
2 134 LEU n 
2 135 ARG n 
2 136 THR n 
2 137 ILE n 
2 138 SER n 
2 139 VAL n 
2 140 ILE n 
2 141 LEU n 
2 142 PHE n 
2 143 LEU n 
2 144 ASN n 
2 145 LYS n 
2 146 GLN n 
2 147 ASP n 
2 148 LEU n 
2 149 LEU n 
2 150 ALA n 
2 151 GLU n 
2 152 LYS n 
2 153 VAL n 
2 154 LEU n 
2 155 ALA n 
2 156 GLY n 
2 157 LYS n 
2 158 SER n 
2 159 LYS n 
2 160 ILE n 
2 161 GLU n 
2 162 ASP n 
2 163 TYR n 
2 164 PHE n 
2 165 PRO n 
2 166 GLU n 
2 167 PHE n 
2 168 ALA n 
2 169 ARG n 
2 170 TYR n 
2 171 THR n 
2 172 THR n 
2 173 PRO n 
2 174 GLU n 
2 175 ASP n 
2 176 ALA n 
2 177 THR n 
2 178 PRO n 
2 179 GLU n 
2 180 PRO n 
2 181 GLY n 
2 182 GLU n 
2 183 ASP n 
2 184 PRO n 
2 185 ARG n 
2 186 VAL n 
2 187 THR n 
2 188 ARG n 
2 189 ALA n 
2 190 LYS n 
2 191 TYR n 
2 192 PHE n 
2 193 ILE n 
2 194 ARG n 
2 195 LYS n 
2 196 GLU n 
2 197 PHE n 
2 198 VAL n 
2 199 ASP n 
2 200 ILE n 
2 201 SER n 
2 202 THR n 
2 203 ALA n 
2 204 SER n 
2 205 GLY n 
2 206 ASP n 
2 207 GLY n 
2 208 ARG n 
2 209 HIS n 
2 210 ILE n 
2 211 CYS n 
2 212 TYR n 
2 213 PRO n 
2 214 HIS n 
2 215 PHE n 
2 216 THR n 
2 217 CYS n 
2 218 ALA n 
2 219 VAL n 
2 220 ASP n 
2 221 THR n 
2 222 GLU n 
2 223 ASN n 
2 224 ALA n 
2 225 ARG n 
2 226 ARG n 
2 227 ILE n 
2 228 PHE n 
2 229 ASN n 
2 230 ASP n 
2 231 CYS n 
2 232 LYS n 
2 233 ASP n 
2 234 ILE n 
2 235 ILE n 
2 236 LEU n 
2 237 GLN n 
2 238 MET n 
2 239 ASN n 
2 240 LEU n 
2 241 ARG n 
2 242 GLU n 
2 243 TYR n 
2 244 ASN n 
2 245 LEU n 
2 246 VAL n 
3 1   MET n 
3 2   HIS n 
3 3   HIS n 
3 4   HIS n 
3 5   HIS n 
3 6   HIS n 
3 7   HIS n 
3 8   LEU n 
3 9   GLU n 
3 10  VAL n 
3 11  LEU n 
3 12  PHE n 
3 13  GLN n 
3 14  GLY n 
3 15  PRO n 
3 16  GLY n 
3 17  SER n 
3 18  SER n 
3 19  GLY n 
3 20  SER n 
3 21  GLU n 
3 22  LEU n 
3 23  ASP n 
3 24  GLN n 
3 25  LEU n 
3 26  ARG n 
3 27  GLN n 
3 28  GLU n 
3 29  ALA n 
3 30  GLU n 
3 31  GLN n 
3 32  LEU n 
3 33  LYS n 
3 34  ASN n 
3 35  GLN n 
3 36  ILE n 
3 37  ARG n 
3 38  ASP n 
3 39  ALA n 
3 40  ARG n 
3 41  LYS n 
3 42  ALA n 
3 43  CYS n 
3 44  ALA n 
3 45  ASP n 
3 46  ALA n 
3 47  THR n 
3 48  LEU n 
3 49  SER n 
3 50  GLN n 
3 51  ILE n 
3 52  THR n 
3 53  ASN n 
3 54  ASN n 
3 55  ILE n 
3 56  ASP n 
3 57  PRO n 
3 58  VAL n 
3 59  GLY n 
3 60  ARG n 
3 61  ILE n 
3 62  GLN n 
3 63  MET n 
3 64  ARG n 
3 65  THR n 
3 66  ARG n 
3 67  ARG n 
3 68  THR n 
3 69  LEU n 
3 70  ARG n 
3 71  GLY n 
3 72  HIS n 
3 73  LEU n 
3 74  ALA n 
3 75  LYS n 
3 76  ILE n 
3 77  TYR n 
3 78  ALA n 
3 79  MET n 
3 80  HIS n 
3 81  TRP n 
3 82  GLY n 
3 83  THR n 
3 84  ASP n 
3 85  SER n 
3 86  ARG n 
3 87  LEU n 
3 88  LEU n 
3 89  VAL n 
3 90  SER n 
3 91  ALA n 
3 92  SER n 
3 93  GLN n 
3 94  ASP n 
3 95  GLY n 
3 96  LYS n 
3 97  LEU n 
3 98  ILE n 
3 99  ILE n 
3 100 TRP n 
3 101 ASP n 
3 102 SER n 
3 103 TYR n 
3 104 THR n 
3 105 THR n 
3 106 ASN n 
3 107 LYS n 
3 108 VAL n 
3 109 HIS n 
3 110 ALA n 
3 111 ILE n 
3 112 PRO n 
3 113 LEU n 
3 114 ARG n 
3 115 SER n 
3 116 SER n 
3 117 TRP n 
3 118 VAL n 
3 119 MET n 
3 120 THR n 
3 121 CYS n 
3 122 ALA n 
3 123 TYR n 
3 124 ALA n 
3 125 PRO n 
3 126 SER n 
3 127 GLY n 
3 128 ASN n 
3 129 TYR n 
3 130 VAL n 
3 131 ALA n 
3 132 CYS n 
3 133 GLY n 
3 134 GLY n 
3 135 LEU n 
3 136 ASP n 
3 137 ASN n 
3 138 ILE n 
3 139 CYS n 
3 140 SER n 
3 141 ILE n 
3 142 TYR n 
3 143 ASN n 
3 144 LEU n 
3 145 LYS n 
3 146 THR n 
3 147 ARG n 
3 148 GLU n 
3 149 GLY n 
3 150 ASN n 
3 151 VAL n 
3 152 ARG n 
3 153 VAL n 
3 154 SER n 
3 155 ARG n 
3 156 GLU n 
3 157 LEU n 
3 158 ALA n 
3 159 GLY n 
3 160 HIS n 
3 161 THR n 
3 162 GLY n 
3 163 TYR n 
3 164 LEU n 
3 165 SER n 
3 166 CYS n 
3 167 CYS n 
3 168 ARG n 
3 169 PHE n 
3 170 LEU n 
3 171 ASP n 
3 172 ASP n 
3 173 ASN n 
3 174 GLN n 
3 175 ILE n 
3 176 VAL n 
3 177 THR n 
3 178 SER n 
3 179 SER n 
3 180 GLY n 
3 181 ASP n 
3 182 THR n 
3 183 THR n 
3 184 CYS n 
3 185 ALA n 
3 186 LEU n 
3 187 TRP n 
3 188 ASP n 
3 189 ILE n 
3 190 GLU n 
3 191 THR n 
3 192 GLY n 
3 193 GLN n 
3 194 GLN n 
3 195 THR n 
3 196 THR n 
3 197 THR n 
3 198 PHE n 
3 199 THR n 
3 200 GLY n 
3 201 HIS n 
3 202 THR n 
3 203 GLY n 
3 204 ASP n 
3 205 VAL n 
3 206 MET n 
3 207 SER n 
3 208 LEU n 
3 209 SER n 
3 210 LEU n 
3 211 ALA n 
3 212 PRO n 
3 213 ASP n 
3 214 THR n 
3 215 ARG n 
3 216 LEU n 
3 217 PHE n 
3 218 VAL n 
3 219 SER n 
3 220 GLY n 
3 221 ALA n 
3 222 CYS n 
3 223 ASP n 
3 224 ALA n 
3 225 SER n 
3 226 ALA n 
3 227 LYS n 
3 228 LEU n 
3 229 TRP n 
3 230 ASP n 
3 231 VAL n 
3 232 ARG n 
3 233 GLU n 
3 234 GLY n 
3 235 MET n 
3 236 CYS n 
3 237 ARG n 
3 238 GLN n 
3 239 THR n 
3 240 PHE n 
3 241 THR n 
3 242 GLY n 
3 243 HIS n 
3 244 GLU n 
3 245 SER n 
3 246 ASP n 
3 247 ILE n 
3 248 ASN n 
3 249 ALA n 
3 250 ILE n 
3 251 CYS n 
3 252 PHE n 
3 253 PHE n 
3 254 PRO n 
3 255 ASN n 
3 256 GLY n 
3 257 ASN n 
3 258 ALA n 
3 259 PHE n 
3 260 ALA n 
3 261 THR n 
3 262 GLY n 
3 263 SER n 
3 264 ASP n 
3 265 ASP n 
3 266 ALA n 
3 267 THR n 
3 268 CYS n 
3 269 ARG n 
3 270 LEU n 
3 271 PHE n 
3 272 ASP n 
3 273 LEU n 
3 274 ARG n 
3 275 ALA n 
3 276 ASP n 
3 277 GLN n 
3 278 GLU n 
3 279 LEU n 
3 280 MET n 
3 281 THR n 
3 282 TYR n 
3 283 SER n 
3 284 HIS n 
3 285 ASP n 
3 286 ASN n 
3 287 ILE n 
3 288 ILE n 
3 289 CYS n 
3 290 GLY n 
3 291 ILE n 
3 292 THR n 
3 293 SER n 
3 294 VAL n 
3 295 SER n 
3 296 PHE n 
3 297 SER n 
3 298 LYS n 
3 299 SER n 
3 300 GLY n 
3 301 ARG n 
3 302 LEU n 
3 303 LEU n 
3 304 LEU n 
3 305 ALA n 
3 306 GLY n 
3 307 TYR n 
3 308 ASP n 
3 309 ASP n 
3 310 PHE n 
3 311 ASN n 
3 312 CYS n 
3 313 ASN n 
3 314 VAL n 
3 315 TRP n 
3 316 ASP n 
3 317 ALA n 
3 318 LEU n 
3 319 LYS n 
3 320 ALA n 
3 321 ASP n 
3 322 ARG n 
3 323 ALA n 
3 324 GLY n 
3 325 VAL n 
3 326 LEU n 
3 327 ALA n 
3 328 GLY n 
3 329 HIS n 
3 330 ASP n 
3 331 ASN n 
3 332 ARG n 
3 333 VAL n 
3 334 SER n 
3 335 CYS n 
3 336 LEU n 
3 337 GLY n 
3 338 VAL n 
3 339 THR n 
3 340 ASP n 
3 341 ASP n 
3 342 GLY n 
3 343 MET n 
3 344 ALA n 
3 345 VAL n 
3 346 ALA n 
3 347 THR n 
3 348 GLY n 
3 349 SER n 
3 350 TRP n 
3 351 ASP n 
3 352 SER n 
3 353 PHE n 
3 354 LEU n 
3 355 LYS n 
3 356 ILE n 
3 357 TRP n 
3 358 ASN n 
4 1   MET n 
4 2   ALA n 
4 3   SER n 
4 4   ASN n 
4 5   ASN n 
4 6   THR n 
4 7   ALA n 
4 8   SER n 
4 9   ILE n 
4 10  ALA n 
4 11  GLN n 
4 12  ALA n 
4 13  ARG n 
4 14  LYS n 
4 15  LEU n 
4 16  VAL n 
4 17  GLU n 
4 18  GLN n 
4 19  LEU n 
4 20  LYS n 
4 21  MET n 
4 22  GLU n 
4 23  ALA n 
4 24  ASN n 
4 25  ILE n 
4 26  ASP n 
4 27  ARG n 
4 28  ILE n 
4 29  LYS n 
4 30  VAL n 
4 31  SER n 
4 32  LYS n 
4 33  ALA n 
4 34  ALA n 
4 35  ALA n 
4 36  ASP n 
4 37  LEU n 
4 38  MET n 
4 39  ALA n 
4 40  TYR n 
4 41  CYS n 
4 42  GLU n 
4 43  ALA n 
4 44  HIS n 
4 45  ALA n 
4 46  LYS n 
4 47  GLU n 
4 48  ASP n 
4 49  PRO n 
4 50  LEU n 
4 51  LEU n 
4 52  THR n 
4 53  PRO n 
4 54  VAL n 
4 55  PRO n 
4 56  ALA n 
4 57  SER n 
4 58  GLU n 
4 59  ASN n 
4 60  PRO n 
4 61  PHE n 
4 62  ARG n 
4 63  GLU n 
4 64  LYS n 
4 65  LYS n 
4 66  PHE n 
4 67  PHE n 
4 68  CYS n 
4 69  ALA n 
4 70  ILE n 
4 71  LEU n 
5 1   ASP n 
5 2   VAL n 
5 3   GLN n 
5 4   LEU n 
5 5   VAL n 
5 6   GLU n 
5 7   SER n 
5 8   GLY n 
5 9   GLY n 
5 10  GLY n 
5 11  LEU n 
5 12  VAL n 
5 13  GLN n 
5 14  PRO n 
5 15  GLY n 
5 16  GLY n 
5 17  SER n 
5 18  ARG n 
5 19  LYS n 
5 20  LEU n 
5 21  SER n 
5 22  CYS n 
5 23  SER n 
5 24  ALA n 
5 25  SER n 
5 26  GLY n 
5 27  PHE n 
5 28  ALA n 
5 29  PHE n 
5 30  SER n 
5 31  SER n 
5 32  PHE n 
5 33  GLY n 
5 34  MET n 
5 35  HIS n 
5 36  TRP n 
5 37  VAL n 
5 38  ARG n 
5 39  GLN n 
5 40  ALA n 
5 41  PRO n 
5 42  GLU n 
5 43  LYS n 
5 44  GLY n 
5 45  LEU n 
5 46  GLU n 
5 47  TRP n 
5 48  VAL n 
5 49  ALA n 
5 50  TYR n 
5 51  ILE n 
5 52  SER n 
5 53  SER n 
5 54  GLY n 
5 55  SER n 
5 56  GLY n 
5 57  THR n 
5 58  ILE n 
5 59  TYR n 
5 60  TYR n 
5 61  ALA n 
5 62  ASP n 
5 63  THR n 
5 64  VAL n 
5 65  LYS n 
5 66  GLY n 
5 67  ARG n 
5 68  PHE n 
5 69  THR n 
5 70  ILE n 
5 71  SER n 
5 72  ARG n 
5 73  ASP n 
5 74  ASP n 
5 75  PRO n 
5 76  LYS n 
5 77  ASN n 
5 78  THR n 
5 79  LEU n 
5 80  PHE n 
5 81  LEU n 
5 82  GLN n 
5 83  MET n 
5 84  THR n 
5 85  SER n 
5 86  LEU n 
5 87  ARG n 
5 88  SER n 
5 89  GLU n 
5 90  ASP n 
5 91  THR n 
5 92  ALA n 
5 93  MET n 
5 94  TYR n 
5 95  TYR n 
5 96  CYS n 
5 97  VAL n 
5 98  ARG n 
5 99  SER n 
5 100 ILE n 
5 101 TYR n 
5 102 TYR n 
5 103 TYR n 
5 104 GLY n 
5 105 SER n 
5 106 SER n 
5 107 PRO n 
5 108 PHE n 
5 109 ASP n 
5 110 PHE n 
5 111 TRP n 
5 112 GLY n 
5 113 GLN n 
5 114 GLY n 
5 115 THR n 
5 116 THR n 
5 117 LEU n 
5 118 THR n 
5 119 VAL n 
5 120 SER n 
5 121 SER n 
5 122 GLY n 
5 123 GLY n 
5 124 GLY n 
5 125 GLY n 
5 126 SER n 
5 127 GLY n 
5 128 GLY n 
5 129 GLY n 
5 130 GLY n 
5 131 SER n 
5 132 GLY n 
5 133 GLY n 
5 134 GLY n 
5 135 GLY n 
5 136 SER n 
5 137 ASP n 
5 138 ILE n 
5 139 VAL n 
5 140 MET n 
5 141 THR n 
5 142 GLN n 
5 143 ALA n 
5 144 THR n 
5 145 SER n 
5 146 SER n 
5 147 VAL n 
5 148 PRO n 
5 149 VAL n 
5 150 THR n 
5 151 PRO n 
5 152 GLY n 
5 153 GLU n 
5 154 SER n 
5 155 VAL n 
5 156 SER n 
5 157 ILE n 
5 158 SER n 
5 159 CYS n 
5 160 ARG n 
5 161 SER n 
5 162 SER n 
5 163 LYS n 
5 164 SER n 
5 165 LEU n 
5 166 LEU n 
5 167 HIS n 
5 168 SER n 
5 169 ASN n 
5 170 GLY n 
5 171 ASN n 
5 172 THR n 
5 173 TYR n 
5 174 LEU n 
5 175 TYR n 
5 176 TRP n 
5 177 PHE n 
5 178 LEU n 
5 179 GLN n 
5 180 ARG n 
5 181 PRO n 
5 182 GLY n 
5 183 GLN n 
5 184 SER n 
5 185 PRO n 
5 186 GLN n 
5 187 LEU n 
5 188 LEU n 
5 189 ILE n 
5 190 TYR n 
5 191 ARG n 
5 192 MET n 
5 193 SER n 
5 194 ASN n 
5 195 LEU n 
5 196 ALA n 
5 197 SER n 
5 198 GLY n 
5 199 VAL n 
5 200 PRO n 
5 201 ASP n 
5 202 ARG n 
5 203 PHE n 
5 204 SER n 
5 205 GLY n 
5 206 SER n 
5 207 GLY n 
5 208 SER n 
5 209 GLY n 
5 210 THR n 
5 211 ALA n 
5 212 PHE n 
5 213 THR n 
5 214 LEU n 
5 215 THR n 
5 216 ILE n 
5 217 SER n 
5 218 ARG n 
5 219 LEU n 
5 220 GLU n 
5 221 ALA n 
5 222 GLU n 
5 223 ASP n 
5 224 VAL n 
5 225 GLY n 
5 226 VAL n 
5 227 TYR n 
5 228 TYR n 
5 229 CYS n 
5 230 MET n 
5 231 GLN n 
5 232 HIS n 
5 233 LEU n 
5 234 GLU n 
5 235 TYR n 
5 236 PRO n 
5 237 LEU n 
5 238 THR n 
5 239 PHE n 
5 240 GLY n 
5 241 ALA n 
5 242 GLY n 
5 243 THR n 
5 244 LYS n 
5 245 LEU n 
5 246 GLU n 
5 247 LEU n 
5 248 LYS n 
5 249 ALA n 
5 250 ALA n 
5 251 ALA n 
5 252 LEU n 
5 253 GLU n 
5 254 VAL n 
5 255 LEU n 
5 256 PHE n 
5 257 GLN n 
5 258 GLY n 
5 259 PRO n 
5 260 HIS n 
5 261 HIS n 
5 262 HIS n 
5 263 HIS n 
5 264 HIS n 
5 265 HIS n 
5 266 HIS n 
5 267 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 471 human ? 'HTR2A, HTR2' ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 246 human ? ?             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 358 human ? GNB1          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ?               
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 71  human ? GNG2          ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ?               
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 267 human ? ?             ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? 'fall armyworm' 
'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? baculovirus ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                                'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                                'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                                'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?                                'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?                                'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                                'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?                                'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ?                                'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                                'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                                'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                                'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?                                'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                                'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                                'C3 H7 N O3'     105.093 
SRO non-polymer         . SEROTONIN       '3-(2-AMINOETHYL)-1H-INDOL-5-OL' 'C10 H12 N2 O'   176.215 
THR 'L-peptide linking' y THREONINE       ?                                'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                                'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                                'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                                'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ASP 2   2   ?   ?   ?   A . n 
A 1 3   ILE 3   3   ?   ?   ?   A . n 
A 1 4   LEU 4   4   ?   ?   ?   A . n 
A 1 5   CYS 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   GLU 7   7   ?   ?   ?   A . n 
A 1 8   ASN 8   8   ?   ?   ?   A . n 
A 1 9   THR 9   9   ?   ?   ?   A . n 
A 1 10  SER 10  10  ?   ?   ?   A . n 
A 1 11  LEU 11  11  ?   ?   ?   A . n 
A 1 12  SER 12  12  ?   ?   ?   A . n 
A 1 13  SER 13  13  ?   ?   ?   A . n 
A 1 14  THR 14  14  ?   ?   ?   A . n 
A 1 15  THR 15  15  ?   ?   ?   A . n 
A 1 16  ASN 16  16  ?   ?   ?   A . n 
A 1 17  SER 17  17  ?   ?   ?   A . n 
A 1 18  LEU 18  18  ?   ?   ?   A . n 
A 1 19  MET 19  19  ?   ?   ?   A . n 
A 1 20  GLN 20  20  ?   ?   ?   A . n 
A 1 21  LEU 21  21  ?   ?   ?   A . n 
A 1 22  ASN 22  22  ?   ?   ?   A . n 
A 1 23  ASP 23  23  ?   ?   ?   A . n 
A 1 24  ASP 24  24  ?   ?   ?   A . n 
A 1 25  THR 25  25  ?   ?   ?   A . n 
A 1 26  ARG 26  26  ?   ?   ?   A . n 
A 1 27  LEU 27  27  ?   ?   ?   A . n 
A 1 28  TYR 28  28  ?   ?   ?   A . n 
A 1 29  SER 29  29  ?   ?   ?   A . n 
A 1 30  ASN 30  30  ?   ?   ?   A . n 
A 1 31  ASP 31  31  ?   ?   ?   A . n 
A 1 32  PHE 32  32  ?   ?   ?   A . n 
A 1 33  ASN 33  33  ?   ?   ?   A . n 
A 1 34  SER 34  34  ?   ?   ?   A . n 
A 1 35  GLY 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  ALA 37  37  ?   ?   ?   A . n 
A 1 38  ASN 38  38  ?   ?   ?   A . n 
A 1 39  THR 39  39  ?   ?   ?   A . n 
A 1 40  SER 40  40  ?   ?   ?   A . n 
A 1 41  ASP 41  41  ?   ?   ?   A . n 
A 1 42  ALA 42  42  ?   ?   ?   A . n 
A 1 43  PHE 43  43  ?   ?   ?   A . n 
A 1 44  ASN 44  44  ?   ?   ?   A . n 
A 1 45  TRP 45  45  ?   ?   ?   A . n 
A 1 46  THR 46  46  ?   ?   ?   A . n 
A 1 47  VAL 47  47  ?   ?   ?   A . n 
A 1 48  ASP 48  48  ?   ?   ?   A . n 
A 1 49  SER 49  49  ?   ?   ?   A . n 
A 1 50  GLU 50  50  ?   ?   ?   A . n 
A 1 51  ASN 51  51  ?   ?   ?   A . n 
A 1 52  ARG 52  52  ?   ?   ?   A . n 
A 1 53  THR 53  53  ?   ?   ?   A . n 
A 1 54  ASN 54  54  ?   ?   ?   A . n 
A 1 55  LEU 55  55  ?   ?   ?   A . n 
A 1 56  SER 56  56  ?   ?   ?   A . n 
A 1 57  CYS 57  57  ?   ?   ?   A . n 
A 1 58  GLU 58  58  ?   ?   ?   A . n 
A 1 59  GLY 59  59  ?   ?   ?   A . n 
A 1 60  CYS 60  60  ?   ?   ?   A . n 
A 1 61  LEU 61  61  ?   ?   ?   A . n 
A 1 62  SER 62  62  ?   ?   ?   A . n 
A 1 63  PRO 63  63  ?   ?   ?   A . n 
A 1 64  SER 64  64  ?   ?   ?   A . n 
A 1 65  CYS 65  65  ?   ?   ?   A . n 
A 1 66  LEU 66  66  ?   ?   ?   A . n 
A 1 67  SER 67  67  ?   ?   ?   A . n 
A 1 68  LEU 68  68  ?   ?   ?   A . n 
A 1 69  LEU 69  69  ?   ?   ?   A . n 
A 1 70  HIS 70  70  ?   ?   ?   A . n 
A 1 71  LEU 71  71  ?   ?   ?   A . n 
A 1 72  GLN 72  72  ?   ?   ?   A . n 
A 1 73  GLU 73  73  ?   ?   ?   A . n 
A 1 74  LYS 74  74  ?   ?   ?   A . n 
A 1 75  ASN 75  75  ?   ?   ?   A . n 
A 1 76  TRP 76  76  ?   ?   ?   A . n 
A 1 77  SER 77  77  ?   ?   ?   A . n 
A 1 78  ALA 78  78  ?   ?   ?   A . n 
A 1 79  LEU 79  79  79  LEU LEU A . n 
A 1 80  LEU 80  80  80  LEU LEU A . n 
A 1 81  THR 81  81  81  THR THR A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  ILE 86  86  86  ILE ILE A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  THR 88  88  88  THR THR A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  GLY 91  91  91  GLY GLY A . n 
A 1 92  ASN 92  92  92  ASN ASN A . n 
A 1 93  ILE 93  93  93  ILE ILE A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  ILE 96  96  96  ILE ILE A . n 
A 1 97  MET 97  97  97  MET MET A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  VAL 99  99  99  VAL VAL A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 GLN 106 106 106 GLN GLN A . n 
A 1 107 ASN 107 107 107 ASN ASN A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 THR 109 109 109 THR THR A . n 
A 1 110 ASN 110 110 110 ASN ASN A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 LEU 113 113 113 LEU LEU A . n 
A 1 114 MET 114 114 114 MET MET A . n 
A 1 115 SER 115 115 115 SER SER A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 ILE 118 118 118 ILE ILE A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 ASP 120 120 120 ASP ASP A . n 
A 1 121 MET 121 121 121 MET MET A . n 
A 1 122 LEU 122 122 122 LEU LEU A . n 
A 1 123 LEU 123 123 123 LEU LEU A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 PHE 125 125 125 PHE PHE A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 MET 128 128 128 MET MET A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 MET 132 132 132 MET MET A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 THR 134 134 134 THR THR A . n 
A 1 135 ILE 135 135 135 ILE ILE A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 ARG 140 140 140 ARG ARG A . n 
A 1 141 TRP 141 141 141 TRP TRP A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 LEU 143 143 143 LEU LEU A . n 
A 1 144 PRO 144 144 144 PRO PRO A . n 
A 1 145 SER 145 145 145 SER SER A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 LEU 147 147 147 LEU LEU A . n 
A 1 148 CYS 148 148 148 CYS CYS A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 TRP 151 151 151 TRP TRP A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 TYR 153 153 153 TYR TYR A . n 
A 1 154 LEU 154 154 154 LEU LEU A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 VAL 156 156 156 VAL VAL A . n 
A 1 157 LEU 157 157 157 LEU LEU A . n 
A 1 158 PHE 158 158 158 PHE PHE A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 THR 160 160 160 THR THR A . n 
A 1 161 ALA 161 161 161 ALA ALA A . n 
A 1 162 SER 162 162 162 SER SER A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 MET 164 164 164 MET MET A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 CYS 167 167 167 CYS CYS A . n 
A 1 168 ALA 168 168 168 ALA ALA A . n 
A 1 169 ILE 169 169 169 ILE ILE A . n 
A 1 170 SER 170 170 170 SER SER A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 ASP 172 172 172 ASP ASP A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 TYR 174 174 174 TYR TYR A . n 
A 1 175 VAL 175 175 175 VAL VAL A . n 
A 1 176 ALA 176 176 176 ALA ALA A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 ASN 179 179 179 ASN ASN A . n 
A 1 180 PRO 180 180 180 PRO PRO A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 HIS 182 182 182 HIS HIS A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 SER 184 184 184 SER SER A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 PHE 186 186 186 PHE PHE A . n 
A 1 187 ASN 187 187 187 ASN ASN A . n 
A 1 188 SER 188 188 188 SER SER A . n 
A 1 189 ARG 189 189 189 ARG ARG A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 LYS 191 191 191 LYS LYS A . n 
A 1 192 ALA 192 192 192 ALA ALA A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 LYS 195 195 195 LYS LYS A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 ILE 197 197 197 ILE ILE A . n 
A 1 198 ALA 198 198 198 ALA ALA A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 TRP 200 200 200 TRP TRP A . n 
A 1 201 THR 201 201 201 THR THR A . n 
A 1 202 ILE 202 202 202 ILE ILE A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 GLY 205 205 205 GLY GLY A . n 
A 1 206 ILE 206 206 206 ILE ILE A . n 
A 1 207 SER 207 207 207 SER SER A . n 
A 1 208 MET 208 208 208 MET MET A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 ILE 210 210 210 ILE ILE A . n 
A 1 211 PRO 211 211 211 PRO PRO A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 PHE 213 213 213 PHE PHE A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 LEU 215 215 215 LEU LEU A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 SER 219 219 219 SER SER A . n 
A 1 220 LYS 220 220 220 LYS LYS A . n 
A 1 221 VAL 221 221 221 VAL VAL A . n 
A 1 222 PHE 222 222 222 PHE PHE A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 GLU 224 224 224 GLU GLU A . n 
A 1 225 GLY 225 225 225 GLY GLY A . n 
A 1 226 SER 226 226 226 SER SER A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 ALA 230 230 230 ALA ALA A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 ASP 232 232 232 ASP ASP A . n 
A 1 233 ASN 233 233 233 ASN ASN A . n 
A 1 234 PHE 234 234 234 PHE PHE A . n 
A 1 235 VAL 235 235 235 VAL VAL A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 GLY 238 238 238 GLY GLY A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 VAL 241 241 241 VAL VAL A . n 
A 1 242 SER 242 242 242 SER SER A . n 
A 1 243 PHE 243 243 243 PHE PHE A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 ILE 245 245 245 ILE ILE A . n 
A 1 246 PRO 246 246 246 PRO PRO A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 THR 248 248 248 THR THR A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 MET 250 250 250 MET MET A . n 
A 1 251 VAL 251 251 251 VAL VAL A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 TYR 254 254 254 TYR TYR A . n 
A 1 255 PHE 255 255 255 PHE PHE A . n 
A 1 256 LEU 256 256 256 LEU LEU A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 SER 260 260 260 SER SER A . n 
A 1 261 LEU 261 261 261 LEU LEU A . n 
A 1 262 GLN 262 262 262 GLN GLN A . n 
A 1 263 LYS 263 263 ?   ?   ?   A . n 
A 1 264 GLU 264 264 ?   ?   ?   A . n 
A 1 265 ALA 265 265 ?   ?   ?   A . n 
A 1 266 THR 266 266 ?   ?   ?   A . n 
A 1 267 LEU 267 267 ?   ?   ?   A . n 
A 1 268 CYS 268 268 ?   ?   ?   A . n 
A 1 269 VAL 269 269 ?   ?   ?   A . n 
A 1 270 SER 270 270 ?   ?   ?   A . n 
A 1 271 ASP 271 271 ?   ?   ?   A . n 
A 1 272 LEU 272 272 ?   ?   ?   A . n 
A 1 273 GLY 273 273 ?   ?   ?   A . n 
A 1 274 THR 274 274 ?   ?   ?   A . n 
A 1 275 ARG 275 275 ?   ?   ?   A . n 
A 1 276 ALA 276 276 ?   ?   ?   A . n 
A 1 277 LYS 277 277 ?   ?   ?   A . n 
A 1 278 LEU 278 278 ?   ?   ?   A . n 
A 1 279 ALA 279 279 ?   ?   ?   A . n 
A 1 280 SER 280 280 ?   ?   ?   A . n 
A 1 281 PHE 281 281 ?   ?   ?   A . n 
A 1 282 SER 282 282 ?   ?   ?   A . n 
A 1 283 PHE 283 283 ?   ?   ?   A . n 
A 1 284 LEU 284 284 ?   ?   ?   A . n 
A 1 285 PRO 285 285 ?   ?   ?   A . n 
A 1 286 GLN 286 286 ?   ?   ?   A . n 
A 1 287 SER 287 287 ?   ?   ?   A . n 
A 1 288 SER 288 288 ?   ?   ?   A . n 
A 1 289 LEU 289 289 ?   ?   ?   A . n 
A 1 290 SER 290 290 ?   ?   ?   A . n 
A 1 291 SER 291 291 ?   ?   ?   A . n 
A 1 292 GLU 292 292 ?   ?   ?   A . n 
A 1 293 LYS 293 293 ?   ?   ?   A . n 
A 1 294 LEU 294 294 ?   ?   ?   A . n 
A 1 295 PHE 295 295 ?   ?   ?   A . n 
A 1 296 GLN 296 296 ?   ?   ?   A . n 
A 1 297 ARG 297 297 ?   ?   ?   A . n 
A 1 298 SER 298 298 ?   ?   ?   A . n 
A 1 299 ILE 299 299 ?   ?   ?   A . n 
A 1 300 HIS 300 300 ?   ?   ?   A . n 
A 1 301 ARG 301 301 ?   ?   ?   A . n 
A 1 302 GLU 302 302 ?   ?   ?   A . n 
A 1 303 PRO 303 303 ?   ?   ?   A . n 
A 1 304 GLY 304 304 ?   ?   ?   A . n 
A 1 305 SER 305 305 ?   ?   ?   A . n 
A 1 306 TYR 306 306 ?   ?   ?   A . n 
A 1 307 THR 307 307 ?   ?   ?   A . n 
A 1 308 GLY 308 308 ?   ?   ?   A . n 
A 1 309 ARG 309 309 ?   ?   ?   A . n 
A 1 310 ARG 310 310 ?   ?   ?   A . n 
A 1 311 THR 311 311 ?   ?   ?   A . n 
A 1 312 MET 312 312 ?   ?   ?   A . n 
A 1 313 GLN 313 313 313 GLN GLN A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 ILE 315 315 315 ILE ILE A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 ASN 317 317 317 ASN ASN A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 GLN 319 319 319 GLN GLN A . n 
A 1 320 LYS 320 320 320 LYS LYS A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 CYS 322 322 322 CYS CYS A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 VAL 328 328 328 VAL VAL A . n 
A 1 329 PHE 329 329 329 PHE PHE A . n 
A 1 330 PHE 330 330 330 PHE PHE A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 PHE 332 332 332 PHE PHE A . n 
A 1 333 VAL 333 333 333 VAL VAL A . n 
A 1 334 VAL 334 334 334 VAL VAL A . n 
A 1 335 MET 335 335 335 MET MET A . n 
A 1 336 TRP 336 336 336 TRP TRP A . n 
A 1 337 CYS 337 337 337 CYS CYS A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 PHE 339 339 339 PHE PHE A . n 
A 1 340 PHE 340 340 340 PHE PHE A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 MET 345 345 345 MET MET A . n 
A 1 346 ALA 346 346 346 ALA ALA A . n 
A 1 347 VAL 347 347 347 VAL VAL A . n 
A 1 348 ILE 348 348 348 ILE ILE A . n 
A 1 349 CYS 349 349 349 CYS CYS A . n 
A 1 350 LYS 350 350 ?   ?   ?   A . n 
A 1 351 GLU 351 351 ?   ?   ?   A . n 
A 1 352 SER 352 352 ?   ?   ?   A . n 
A 1 353 CYS 353 353 ?   ?   ?   A . n 
A 1 354 ASN 354 354 ?   ?   ?   A . n 
A 1 355 GLU 355 355 ?   ?   ?   A . n 
A 1 356 ASP 356 356 356 ASP ASP A . n 
A 1 357 VAL 357 357 357 VAL VAL A . n 
A 1 358 ILE 358 358 358 ILE ILE A . n 
A 1 359 GLY 359 359 359 GLY GLY A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 LEU 361 361 361 LEU LEU A . n 
A 1 362 LEU 362 362 362 LEU LEU A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 VAL 364 364 364 VAL VAL A . n 
A 1 365 PHE 365 365 365 PHE PHE A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 TRP 367 367 367 TRP TRP A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 GLY 369 369 369 GLY GLY A . n 
A 1 370 TYR 370 370 370 TYR TYR A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 SER 372 372 372 SER SER A . n 
A 1 373 SER 373 373 373 SER SER A . n 
A 1 374 ALA 374 374 374 ALA ALA A . n 
A 1 375 VAL 375 375 375 VAL VAL A . n 
A 1 376 ASN 376 376 376 ASN ASN A . n 
A 1 377 PRO 377 377 377 PRO PRO A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 TYR 380 380 380 TYR TYR A . n 
A 1 381 THR 381 381 381 THR THR A . n 
A 1 382 LEU 382 382 382 LEU LEU A . n 
A 1 383 PHE 383 383 383 PHE PHE A . n 
A 1 384 ASN 384 384 384 ASN ASN A . n 
A 1 385 LYS 385 385 385 LYS LYS A . n 
A 1 386 THR 386 386 386 THR THR A . n 
A 1 387 TYR 387 387 387 TYR TYR A . n 
A 1 388 ARG 388 388 388 ARG ARG A . n 
A 1 389 SER 389 389 389 SER SER A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 PHE 391 391 ?   ?   ?   A . n 
A 1 392 SER 392 392 ?   ?   ?   A . n 
A 1 393 ARG 393 393 ?   ?   ?   A . n 
A 1 394 TYR 394 394 ?   ?   ?   A . n 
A 1 395 ILE 395 395 ?   ?   ?   A . n 
A 1 396 GLN 396 396 ?   ?   ?   A . n 
A 1 397 CYS 397 397 ?   ?   ?   A . n 
A 1 398 GLN 398 398 ?   ?   ?   A . n 
A 1 399 TYR 399 399 ?   ?   ?   A . n 
A 1 400 LYS 400 400 ?   ?   ?   A . n 
A 1 401 GLU 401 401 ?   ?   ?   A . n 
A 1 402 ASN 402 402 ?   ?   ?   A . n 
A 1 403 LYS 403 403 ?   ?   ?   A . n 
A 1 404 LYS 404 404 ?   ?   ?   A . n 
A 1 405 PRO 405 405 ?   ?   ?   A . n 
A 1 406 LEU 406 406 ?   ?   ?   A . n 
A 1 407 GLN 407 407 ?   ?   ?   A . n 
A 1 408 LEU 408 408 ?   ?   ?   A . n 
A 1 409 ILE 409 409 ?   ?   ?   A . n 
A 1 410 LEU 410 410 ?   ?   ?   A . n 
A 1 411 VAL 411 411 ?   ?   ?   A . n 
A 1 412 ASN 412 412 ?   ?   ?   A . n 
A 1 413 THR 413 413 ?   ?   ?   A . n 
A 1 414 ILE 414 414 ?   ?   ?   A . n 
A 1 415 PRO 415 415 ?   ?   ?   A . n 
A 1 416 ALA 416 416 ?   ?   ?   A . n 
A 1 417 LEU 417 417 ?   ?   ?   A . n 
A 1 418 ALA 418 418 ?   ?   ?   A . n 
A 1 419 TYR 419 419 ?   ?   ?   A . n 
A 1 420 LYS 420 420 ?   ?   ?   A . n 
A 1 421 SER 421 421 ?   ?   ?   A . n 
A 1 422 SER 422 422 ?   ?   ?   A . n 
A 1 423 GLN 423 423 ?   ?   ?   A . n 
A 1 424 LEU 424 424 ?   ?   ?   A . n 
A 1 425 GLN 425 425 ?   ?   ?   A . n 
A 1 426 MET 426 426 ?   ?   ?   A . n 
A 1 427 GLY 427 427 ?   ?   ?   A . n 
A 1 428 GLN 428 428 ?   ?   ?   A . n 
A 1 429 LYS 429 429 ?   ?   ?   A . n 
A 1 430 LYS 430 430 ?   ?   ?   A . n 
A 1 431 ASN 431 431 ?   ?   ?   A . n 
A 1 432 SER 432 432 ?   ?   ?   A . n 
A 1 433 LYS 433 433 ?   ?   ?   A . n 
A 1 434 GLN 434 434 ?   ?   ?   A . n 
A 1 435 ASP 435 435 ?   ?   ?   A . n 
A 1 436 ALA 436 436 ?   ?   ?   A . n 
A 1 437 LYS 437 437 ?   ?   ?   A . n 
A 1 438 THR 438 438 ?   ?   ?   A . n 
A 1 439 THR 439 439 ?   ?   ?   A . n 
A 1 440 ASP 440 440 ?   ?   ?   A . n 
A 1 441 ASN 441 441 ?   ?   ?   A . n 
A 1 442 ASP 442 442 ?   ?   ?   A . n 
A 1 443 CYS 443 443 ?   ?   ?   A . n 
A 1 444 SER 444 444 ?   ?   ?   A . n 
A 1 445 MET 445 445 ?   ?   ?   A . n 
A 1 446 VAL 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 LEU 448 448 ?   ?   ?   A . n 
A 1 449 GLY 449 449 ?   ?   ?   A . n 
A 1 450 LYS 450 450 ?   ?   ?   A . n 
A 1 451 GLN 451 451 ?   ?   ?   A . n 
A 1 452 HIS 452 452 ?   ?   ?   A . n 
A 1 453 SER 453 453 ?   ?   ?   A . n 
A 1 454 GLU 454 454 ?   ?   ?   A . n 
A 1 455 GLU 455 455 ?   ?   ?   A . n 
A 1 456 ALA 456 456 ?   ?   ?   A . n 
A 1 457 SER 457 457 ?   ?   ?   A . n 
A 1 458 LYS 458 458 ?   ?   ?   A . n 
A 1 459 ASP 459 459 ?   ?   ?   A . n 
A 1 460 ASN 460 460 ?   ?   ?   A . n 
A 1 461 SER 461 461 ?   ?   ?   A . n 
A 1 462 ASP 462 462 ?   ?   ?   A . n 
A 1 463 GLY 463 463 ?   ?   ?   A . n 
A 1 464 VAL 464 464 ?   ?   ?   A . n 
A 1 465 ASN 465 465 ?   ?   ?   A . n 
A 1 466 GLU 466 466 ?   ?   ?   A . n 
A 1 467 LYS 467 467 ?   ?   ?   A . n 
A 1 468 VAL 468 468 ?   ?   ?   A . n 
A 1 469 SER 469 469 ?   ?   ?   A . n 
A 1 470 CYS 470 470 ?   ?   ?   A . n 
A 1 471 VAL 471 471 ?   ?   ?   A . n 
B 2 1   MET 1   1   ?   ?   ?   B . n 
B 2 2   GLY 2   2   ?   ?   ?   B . n 
B 2 3   SER 3   3   ?   ?   ?   B . n 
B 2 4   THR 4   4   4   THR THR B . n 
B 2 5   VAL 5   5   5   VAL VAL B . n 
B 2 6   SER 6   6   6   SER SER B . n 
B 2 7   ALA 7   7   7   ALA ALA B . n 
B 2 8   GLU 8   8   8   GLU GLU B . n 
B 2 9   ASP 9   9   9   ASP ASP B . n 
B 2 10  LYS 10  10  10  LYS LYS B . n 
B 2 11  ALA 11  11  11  ALA ALA B . n 
B 2 12  ALA 12  12  12  ALA ALA B . n 
B 2 13  ALA 13  13  13  ALA ALA B . n 
B 2 14  GLU 14  14  14  GLU GLU B . n 
B 2 15  ARG 15  15  15  ARG ARG B . n 
B 2 16  SER 16  16  16  SER SER B . n 
B 2 17  LYS 17  17  17  LYS LYS B . n 
B 2 18  MET 18  18  18  MET MET B . n 
B 2 19  ILE 19  19  19  ILE ILE B . n 
B 2 20  ASP 20  20  20  ASP ASP B . n 
B 2 21  LYS 21  21  21  LYS LYS B . n 
B 2 22  ASN 22  22  22  ASN ASN B . n 
B 2 23  LEU 23  23  23  LEU LEU B . n 
B 2 24  ARG 24  24  24  ARG ARG B . n 
B 2 25  GLU 25  25  25  GLU GLU B . n 
B 2 26  ASP 26  26  26  ASP ASP B . n 
B 2 27  GLY 27  27  27  GLY GLY B . n 
B 2 28  GLU 28  28  28  GLU GLU B . n 
B 2 29  LYS 29  29  29  LYS LYS B . n 
B 2 30  ALA 30  30  30  ALA ALA B . n 
B 2 31  ARG 31  31  31  ARG ARG B . n 
B 2 32  ARG 32  32  32  ARG ARG B . n 
B 2 33  THR 33  33  33  THR THR B . n 
B 2 34  LEU 34  34  34  LEU LEU B . n 
B 2 35  ARG 35  35  35  ARG ARG B . n 
B 2 36  LEU 36  36  36  LEU LEU B . n 
B 2 37  LEU 37  37  37  LEU LEU B . n 
B 2 38  LEU 38  38  38  LEU LEU B . n 
B 2 39  LEU 39  39  39  LEU LEU B . n 
B 2 40  GLY 40  40  40  GLY GLY B . n 
B 2 41  ALA 41  41  41  ALA ALA B . n 
B 2 42  ASP 42  42  42  ASP ASP B . n 
B 2 43  ASN 43  43  43  ASN ASN B . n 
B 2 44  SER 44  44  44  SER SER B . n 
B 2 45  GLY 45  45  45  GLY GLY B . n 
B 2 46  LYS 46  46  46  LYS LYS B . n 
B 2 47  SER 47  47  47  SER SER B . n 
B 2 48  THR 48  48  48  THR THR B . n 
B 2 49  ILE 49  49  49  ILE ILE B . n 
B 2 50  VAL 50  50  50  VAL VAL B . n 
B 2 51  LYS 51  51  51  LYS LYS B . n 
B 2 52  GLN 52  52  52  GLN GLN B . n 
B 2 53  MET 53  53  53  MET MET B . n 
B 2 54  ARG 54  54  54  ARG ARG B . n 
B 2 55  ILE 55  55  ?   ?   ?   B . n 
B 2 56  LEU 56  56  ?   ?   ?   B . n 
B 2 57  HIS 57  57  ?   ?   ?   B . n 
B 2 58  GLY 58  58  ?   ?   ?   B . n 
B 2 59  GLY 59  59  ?   ?   ?   B . n 
B 2 60  SER 60  60  ?   ?   ?   B . n 
B 2 61  GLY 61  61  ?   ?   ?   B . n 
B 2 62  GLY 62  62  ?   ?   ?   B . n 
B 2 63  SER 63  63  ?   ?   ?   B . n 
B 2 64  GLY 64  64  ?   ?   ?   B . n 
B 2 65  GLY 65  65  ?   ?   ?   B . n 
B 2 66  THR 66  66  66  THR THR B . n 
B 2 67  SER 67  67  67  SER SER B . n 
B 2 68  GLY 68  68  68  GLY GLY B . n 
B 2 69  ILE 69  69  69  ILE ILE B . n 
B 2 70  PHE 70  70  70  PHE PHE B . n 
B 2 71  GLU 71  71  71  GLU GLU B . n 
B 2 72  THR 72  72  72  THR THR B . n 
B 2 73  LYS 73  73  73  LYS LYS B . n 
B 2 74  PHE 74  74  74  PHE PHE B . n 
B 2 75  GLN 75  75  75  GLN GLN B . n 
B 2 76  VAL 76  76  76  VAL VAL B . n 
B 2 77  ASP 77  77  77  ASP ASP B . n 
B 2 78  LYS 78  78  78  LYS LYS B . n 
B 2 79  VAL 79  79  79  VAL VAL B . n 
B 2 80  ASN 80  80  80  ASN ASN B . n 
B 2 81  PHE 81  81  81  PHE PHE B . n 
B 2 82  HIS 82  82  82  HIS HIS B . n 
B 2 83  MET 83  83  83  MET MET B . n 
B 2 84  PHE 84  84  84  PHE PHE B . n 
B 2 85  ASP 85  85  85  ASP ASP B . n 
B 2 86  VAL 86  86  86  VAL VAL B . n 
B 2 87  GLY 87  87  87  GLY GLY B . n 
B 2 88  GLY 88  88  88  GLY GLY B . n 
B 2 89  GLN 89  89  89  GLN GLN B . n 
B 2 90  ARG 90  90  90  ARG ARG B . n 
B 2 91  ASP 91  91  91  ASP ASP B . n 
B 2 92  GLU 92  92  92  GLU GLU B . n 
B 2 93  ARG 93  93  93  ARG ARG B . n 
B 2 94  ARG 94  94  94  ARG ARG B . n 
B 2 95  LYS 95  95  95  LYS LYS B . n 
B 2 96  TRP 96  96  96  TRP TRP B . n 
B 2 97  ILE 97  97  97  ILE ILE B . n 
B 2 98  GLN 98  98  98  GLN GLN B . n 
B 2 99  CYS 99  99  99  CYS CYS B . n 
B 2 100 PHE 100 100 100 PHE PHE B . n 
B 2 101 ASN 101 101 101 ASN ASN B . n 
B 2 102 ASP 102 102 102 ASP ASP B . n 
B 2 103 VAL 103 103 103 VAL VAL B . n 
B 2 104 THR 104 104 104 THR THR B . n 
B 2 105 ALA 105 105 105 ALA ALA B . n 
B 2 106 ILE 106 106 106 ILE ILE B . n 
B 2 107 ILE 107 107 107 ILE ILE B . n 
B 2 108 PHE 108 108 108 PHE PHE B . n 
B 2 109 VAL 109 109 109 VAL VAL B . n 
B 2 110 VAL 110 110 110 VAL VAL B . n 
B 2 111 ASP 111 111 111 ASP ASP B . n 
B 2 112 SER 112 112 112 SER SER B . n 
B 2 113 SER 113 113 113 SER SER B . n 
B 2 114 ASP 114 114 114 ASP ASP B . n 
B 2 115 TYR 115 115 115 TYR TYR B . n 
B 2 116 ASN 116 116 116 ASN ASN B . n 
B 2 117 ARG 117 117 117 ARG ARG B . n 
B 2 118 LEU 118 118 118 LEU LEU B . n 
B 2 119 GLN 119 119 119 GLN GLN B . n 
B 2 120 GLU 120 120 120 GLU GLU B . n 
B 2 121 ALA 121 121 121 ALA ALA B . n 
B 2 122 LEU 122 122 122 LEU LEU B . n 
B 2 123 ASN 123 123 123 ASN ASN B . n 
B 2 124 ASP 124 124 124 ASP ASP B . n 
B 2 125 PHE 125 125 125 PHE PHE B . n 
B 2 126 LYS 126 126 126 LYS LYS B . n 
B 2 127 SER 127 127 127 SER SER B . n 
B 2 128 ILE 128 128 128 ILE ILE B . n 
B 2 129 TRP 129 129 129 TRP TRP B . n 
B 2 130 ASN 130 130 130 ASN ASN B . n 
B 2 131 ASN 131 131 131 ASN ASN B . n 
B 2 132 ARG 132 132 132 ARG ARG B . n 
B 2 133 TRP 133 133 133 TRP TRP B . n 
B 2 134 LEU 134 134 134 LEU LEU B . n 
B 2 135 ARG 135 135 135 ARG ARG B . n 
B 2 136 THR 136 136 136 THR THR B . n 
B 2 137 ILE 137 137 137 ILE ILE B . n 
B 2 138 SER 138 138 138 SER SER B . n 
B 2 139 VAL 139 139 139 VAL VAL B . n 
B 2 140 ILE 140 140 140 ILE ILE B . n 
B 2 141 LEU 141 141 141 LEU LEU B . n 
B 2 142 PHE 142 142 142 PHE PHE B . n 
B 2 143 LEU 143 143 143 LEU LEU B . n 
B 2 144 ASN 144 144 144 ASN ASN B . n 
B 2 145 LYS 145 145 145 LYS LYS B . n 
B 2 146 GLN 146 146 146 GLN GLN B . n 
B 2 147 ASP 147 147 147 ASP ASP B . n 
B 2 148 LEU 148 148 148 LEU LEU B . n 
B 2 149 LEU 149 149 149 LEU LEU B . n 
B 2 150 ALA 150 150 150 ALA ALA B . n 
B 2 151 GLU 151 151 151 GLU GLU B . n 
B 2 152 LYS 152 152 152 LYS LYS B . n 
B 2 153 VAL 153 153 153 VAL VAL B . n 
B 2 154 LEU 154 154 154 LEU LEU B . n 
B 2 155 ALA 155 155 155 ALA ALA B . n 
B 2 156 GLY 156 156 156 GLY GLY B . n 
B 2 157 LYS 157 157 157 LYS LYS B . n 
B 2 158 SER 158 158 158 SER SER B . n 
B 2 159 LYS 159 159 159 LYS LYS B . n 
B 2 160 ILE 160 160 160 ILE ILE B . n 
B 2 161 GLU 161 161 161 GLU GLU B . n 
B 2 162 ASP 162 162 162 ASP ASP B . n 
B 2 163 TYR 163 163 163 TYR TYR B . n 
B 2 164 PHE 164 164 164 PHE PHE B . n 
B 2 165 PRO 165 165 165 PRO PRO B . n 
B 2 166 GLU 166 166 166 GLU GLU B . n 
B 2 167 PHE 167 167 167 PHE PHE B . n 
B 2 168 ALA 168 168 168 ALA ALA B . n 
B 2 169 ARG 169 169 169 ARG ARG B . n 
B 2 170 TYR 170 170 170 TYR TYR B . n 
B 2 171 THR 171 171 171 THR THR B . n 
B 2 172 THR 172 172 172 THR THR B . n 
B 2 173 PRO 173 173 173 PRO PRO B . n 
B 2 174 GLU 174 174 174 GLU GLU B . n 
B 2 175 ASP 175 175 175 ASP ASP B . n 
B 2 176 ALA 176 176 176 ALA ALA B . n 
B 2 177 THR 177 177 177 THR THR B . n 
B 2 178 PRO 178 178 178 PRO PRO B . n 
B 2 179 GLU 179 179 179 GLU GLU B . n 
B 2 180 PRO 180 180 180 PRO PRO B . n 
B 2 181 GLY 181 181 181 GLY GLY B . n 
B 2 182 GLU 182 182 182 GLU GLU B . n 
B 2 183 ASP 183 183 183 ASP ASP B . n 
B 2 184 PRO 184 184 184 PRO PRO B . n 
B 2 185 ARG 185 185 185 ARG ARG B . n 
B 2 186 VAL 186 186 186 VAL VAL B . n 
B 2 187 THR 187 187 187 THR THR B . n 
B 2 188 ARG 188 188 188 ARG ARG B . n 
B 2 189 ALA 189 189 189 ALA ALA B . n 
B 2 190 LYS 190 190 190 LYS LYS B . n 
B 2 191 TYR 191 191 191 TYR TYR B . n 
B 2 192 PHE 192 192 192 PHE PHE B . n 
B 2 193 ILE 193 193 193 ILE ILE B . n 
B 2 194 ARG 194 194 194 ARG ARG B . n 
B 2 195 LYS 195 195 195 LYS LYS B . n 
B 2 196 GLU 196 196 196 GLU GLU B . n 
B 2 197 PHE 197 197 197 PHE PHE B . n 
B 2 198 VAL 198 198 198 VAL VAL B . n 
B 2 199 ASP 199 199 199 ASP ASP B . n 
B 2 200 ILE 200 200 200 ILE ILE B . n 
B 2 201 SER 201 201 201 SER SER B . n 
B 2 202 THR 202 202 202 THR THR B . n 
B 2 203 ALA 203 203 203 ALA ALA B . n 
B 2 204 SER 204 204 204 SER SER B . n 
B 2 205 GLY 205 205 205 GLY GLY B . n 
B 2 206 ASP 206 206 206 ASP ASP B . n 
B 2 207 GLY 207 207 207 GLY GLY B . n 
B 2 208 ARG 208 208 208 ARG ARG B . n 
B 2 209 HIS 209 209 209 HIS HIS B . n 
B 2 210 ILE 210 210 210 ILE ILE B . n 
B 2 211 CYS 211 211 211 CYS CYS B . n 
B 2 212 TYR 212 212 212 TYR TYR B . n 
B 2 213 PRO 213 213 213 PRO PRO B . n 
B 2 214 HIS 214 214 214 HIS HIS B . n 
B 2 215 PHE 215 215 215 PHE PHE B . n 
B 2 216 THR 216 216 216 THR THR B . n 
B 2 217 CYS 217 217 217 CYS CYS B . n 
B 2 218 ALA 218 218 218 ALA ALA B . n 
B 2 219 VAL 219 219 219 VAL VAL B . n 
B 2 220 ASP 220 220 220 ASP ASP B . n 
B 2 221 THR 221 221 221 THR THR B . n 
B 2 222 GLU 222 222 222 GLU GLU B . n 
B 2 223 ASN 223 223 223 ASN ASN B . n 
B 2 224 ALA 224 224 224 ALA ALA B . n 
B 2 225 ARG 225 225 225 ARG ARG B . n 
B 2 226 ARG 226 226 226 ARG ARG B . n 
B 2 227 ILE 227 227 227 ILE ILE B . n 
B 2 228 PHE 228 228 228 PHE PHE B . n 
B 2 229 ASN 229 229 229 ASN ASN B . n 
B 2 230 ASP 230 230 230 ASP ASP B . n 
B 2 231 CYS 231 231 231 CYS CYS B . n 
B 2 232 LYS 232 232 232 LYS LYS B . n 
B 2 233 ASP 233 233 233 ASP ASP B . n 
B 2 234 ILE 234 234 234 ILE ILE B . n 
B 2 235 ILE 235 235 235 ILE ILE B . n 
B 2 236 LEU 236 236 236 LEU LEU B . n 
B 2 237 GLN 237 237 237 GLN GLN B . n 
B 2 238 MET 238 238 238 MET MET B . n 
B 2 239 ASN 239 239 239 ASN ASN B . n 
B 2 240 LEU 240 240 240 LEU LEU B . n 
B 2 241 ARG 241 241 241 ARG ARG B . n 
B 2 242 GLU 242 242 242 GLU GLU B . n 
B 2 243 TYR 243 243 243 TYR TYR B . n 
B 2 244 ASN 244 244 244 ASN ASN B . n 
B 2 245 LEU 245 245 245 LEU LEU B . n 
B 2 246 VAL 246 246 246 VAL VAL B . n 
C 3 1   MET 1   -17 ?   ?   ?   C . n 
C 3 2   HIS 2   -16 ?   ?   ?   C . n 
C 3 3   HIS 3   -15 ?   ?   ?   C . n 
C 3 4   HIS 4   -14 ?   ?   ?   C . n 
C 3 5   HIS 5   -13 ?   ?   ?   C . n 
C 3 6   HIS 6   -12 ?   ?   ?   C . n 
C 3 7   HIS 7   -11 ?   ?   ?   C . n 
C 3 8   LEU 8   -10 ?   ?   ?   C . n 
C 3 9   GLU 9   -9  ?   ?   ?   C . n 
C 3 10  VAL 10  -8  ?   ?   ?   C . n 
C 3 11  LEU 11  -7  ?   ?   ?   C . n 
C 3 12  PHE 12  -6  ?   ?   ?   C . n 
C 3 13  GLN 13  -5  ?   ?   ?   C . n 
C 3 14  GLY 14  -4  ?   ?   ?   C . n 
C 3 15  PRO 15  -3  ?   ?   ?   C . n 
C 3 16  GLY 16  -2  ?   ?   ?   C . n 
C 3 17  SER 17  -1  ?   ?   ?   C . n 
C 3 18  SER 18  0   ?   ?   ?   C . n 
C 3 19  GLY 19  1   ?   ?   ?   C . n 
C 3 20  SER 20  2   ?   ?   ?   C . n 
C 3 21  GLU 21  3   3   GLU GLU C . n 
C 3 22  LEU 22  4   4   LEU LEU C . n 
C 3 23  ASP 23  5   5   ASP ASP C . n 
C 3 24  GLN 24  6   6   GLN GLN C . n 
C 3 25  LEU 25  7   7   LEU LEU C . n 
C 3 26  ARG 26  8   8   ARG ARG C . n 
C 3 27  GLN 27  9   9   GLN GLN C . n 
C 3 28  GLU 28  10  10  GLU GLU C . n 
C 3 29  ALA 29  11  11  ALA ALA C . n 
C 3 30  GLU 30  12  12  GLU GLU C . n 
C 3 31  GLN 31  13  13  GLN GLN C . n 
C 3 32  LEU 32  14  14  LEU LEU C . n 
C 3 33  LYS 33  15  15  LYS LYS C . n 
C 3 34  ASN 34  16  16  ASN ASN C . n 
C 3 35  GLN 35  17  17  GLN GLN C . n 
C 3 36  ILE 36  18  18  ILE ILE C . n 
C 3 37  ARG 37  19  19  ARG ARG C . n 
C 3 38  ASP 38  20  20  ASP ASP C . n 
C 3 39  ALA 39  21  21  ALA ALA C . n 
C 3 40  ARG 40  22  22  ARG ARG C . n 
C 3 41  LYS 41  23  23  LYS LYS C . n 
C 3 42  ALA 42  24  24  ALA ALA C . n 
C 3 43  CYS 43  25  25  CYS CYS C . n 
C 3 44  ALA 44  26  26  ALA ALA C . n 
C 3 45  ASP 45  27  27  ASP ASP C . n 
C 3 46  ALA 46  28  28  ALA ALA C . n 
C 3 47  THR 47  29  29  THR THR C . n 
C 3 48  LEU 48  30  30  LEU LEU C . n 
C 3 49  SER 49  31  31  SER SER C . n 
C 3 50  GLN 50  32  32  GLN GLN C . n 
C 3 51  ILE 51  33  33  ILE ILE C . n 
C 3 52  THR 52  34  34  THR THR C . n 
C 3 53  ASN 53  35  35  ASN ASN C . n 
C 3 54  ASN 54  36  36  ASN ASN C . n 
C 3 55  ILE 55  37  37  ILE ILE C . n 
C 3 56  ASP 56  38  38  ASP ASP C . n 
C 3 57  PRO 57  39  39  PRO PRO C . n 
C 3 58  VAL 58  40  40  VAL VAL C . n 
C 3 59  GLY 59  41  41  GLY GLY C . n 
C 3 60  ARG 60  42  42  ARG ARG C . n 
C 3 61  ILE 61  43  43  ILE ILE C . n 
C 3 62  GLN 62  44  44  GLN GLN C . n 
C 3 63  MET 63  45  45  MET MET C . n 
C 3 64  ARG 64  46  46  ARG ARG C . n 
C 3 65  THR 65  47  47  THR THR C . n 
C 3 66  ARG 66  48  48  ARG ARG C . n 
C 3 67  ARG 67  49  49  ARG ARG C . n 
C 3 68  THR 68  50  50  THR THR C . n 
C 3 69  LEU 69  51  51  LEU LEU C . n 
C 3 70  ARG 70  52  52  ARG ARG C . n 
C 3 71  GLY 71  53  53  GLY GLY C . n 
C 3 72  HIS 72  54  54  HIS HIS C . n 
C 3 73  LEU 73  55  55  LEU LEU C . n 
C 3 74  ALA 74  56  56  ALA ALA C . n 
C 3 75  LYS 75  57  57  LYS LYS C . n 
C 3 76  ILE 76  58  58  ILE ILE C . n 
C 3 77  TYR 77  59  59  TYR TYR C . n 
C 3 78  ALA 78  60  60  ALA ALA C . n 
C 3 79  MET 79  61  61  MET MET C . n 
C 3 80  HIS 80  62  62  HIS HIS C . n 
C 3 81  TRP 81  63  63  TRP TRP C . n 
C 3 82  GLY 82  64  64  GLY GLY C . n 
C 3 83  THR 83  65  65  THR THR C . n 
C 3 84  ASP 84  66  66  ASP ASP C . n 
C 3 85  SER 85  67  67  SER SER C . n 
C 3 86  ARG 86  68  68  ARG ARG C . n 
C 3 87  LEU 87  69  69  LEU LEU C . n 
C 3 88  LEU 88  70  70  LEU LEU C . n 
C 3 89  VAL 89  71  71  VAL VAL C . n 
C 3 90  SER 90  72  72  SER SER C . n 
C 3 91  ALA 91  73  73  ALA ALA C . n 
C 3 92  SER 92  74  74  SER SER C . n 
C 3 93  GLN 93  75  75  GLN GLN C . n 
C 3 94  ASP 94  76  76  ASP ASP C . n 
C 3 95  GLY 95  77  77  GLY GLY C . n 
C 3 96  LYS 96  78  78  LYS LYS C . n 
C 3 97  LEU 97  79  79  LEU LEU C . n 
C 3 98  ILE 98  80  80  ILE ILE C . n 
C 3 99  ILE 99  81  81  ILE ILE C . n 
C 3 100 TRP 100 82  82  TRP TRP C . n 
C 3 101 ASP 101 83  83  ASP ASP C . n 
C 3 102 SER 102 84  84  SER SER C . n 
C 3 103 TYR 103 85  85  TYR TYR C . n 
C 3 104 THR 104 86  86  THR THR C . n 
C 3 105 THR 105 87  87  THR THR C . n 
C 3 106 ASN 106 88  88  ASN ASN C . n 
C 3 107 LYS 107 89  89  LYS LYS C . n 
C 3 108 VAL 108 90  90  VAL VAL C . n 
C 3 109 HIS 109 91  91  HIS HIS C . n 
C 3 110 ALA 110 92  92  ALA ALA C . n 
C 3 111 ILE 111 93  93  ILE ILE C . n 
C 3 112 PRO 112 94  94  PRO PRO C . n 
C 3 113 LEU 113 95  95  LEU LEU C . n 
C 3 114 ARG 114 96  96  ARG ARG C . n 
C 3 115 SER 115 97  97  SER SER C . n 
C 3 116 SER 116 98  98  SER SER C . n 
C 3 117 TRP 117 99  99  TRP TRP C . n 
C 3 118 VAL 118 100 100 VAL VAL C . n 
C 3 119 MET 119 101 101 MET MET C . n 
C 3 120 THR 120 102 102 THR THR C . n 
C 3 121 CYS 121 103 103 CYS CYS C . n 
C 3 122 ALA 122 104 104 ALA ALA C . n 
C 3 123 TYR 123 105 105 TYR TYR C . n 
C 3 124 ALA 124 106 106 ALA ALA C . n 
C 3 125 PRO 125 107 107 PRO PRO C . n 
C 3 126 SER 126 108 108 SER SER C . n 
C 3 127 GLY 127 109 109 GLY GLY C . n 
C 3 128 ASN 128 110 110 ASN ASN C . n 
C 3 129 TYR 129 111 111 TYR TYR C . n 
C 3 130 VAL 130 112 112 VAL VAL C . n 
C 3 131 ALA 131 113 113 ALA ALA C . n 
C 3 132 CYS 132 114 114 CYS CYS C . n 
C 3 133 GLY 133 115 115 GLY GLY C . n 
C 3 134 GLY 134 116 116 GLY GLY C . n 
C 3 135 LEU 135 117 117 LEU LEU C . n 
C 3 136 ASP 136 118 118 ASP ASP C . n 
C 3 137 ASN 137 119 119 ASN ASN C . n 
C 3 138 ILE 138 120 120 ILE ILE C . n 
C 3 139 CYS 139 121 121 CYS CYS C . n 
C 3 140 SER 140 122 122 SER SER C . n 
C 3 141 ILE 141 123 123 ILE ILE C . n 
C 3 142 TYR 142 124 124 TYR TYR C . n 
C 3 143 ASN 143 125 125 ASN ASN C . n 
C 3 144 LEU 144 126 126 LEU LEU C . n 
C 3 145 LYS 145 127 127 LYS LYS C . n 
C 3 146 THR 146 128 128 THR THR C . n 
C 3 147 ARG 147 129 129 ARG ARG C . n 
C 3 148 GLU 148 130 130 GLU GLU C . n 
C 3 149 GLY 149 131 131 GLY GLY C . n 
C 3 150 ASN 150 132 132 ASN ASN C . n 
C 3 151 VAL 151 133 133 VAL VAL C . n 
C 3 152 ARG 152 134 134 ARG ARG C . n 
C 3 153 VAL 153 135 135 VAL VAL C . n 
C 3 154 SER 154 136 136 SER SER C . n 
C 3 155 ARG 155 137 137 ARG ARG C . n 
C 3 156 GLU 156 138 138 GLU GLU C . n 
C 3 157 LEU 157 139 139 LEU LEU C . n 
C 3 158 ALA 158 140 140 ALA ALA C . n 
C 3 159 GLY 159 141 141 GLY GLY C . n 
C 3 160 HIS 160 142 142 HIS HIS C . n 
C 3 161 THR 161 143 143 THR THR C . n 
C 3 162 GLY 162 144 144 GLY GLY C . n 
C 3 163 TYR 163 145 145 TYR TYR C . n 
C 3 164 LEU 164 146 146 LEU LEU C . n 
C 3 165 SER 165 147 147 SER SER C . n 
C 3 166 CYS 166 148 148 CYS CYS C . n 
C 3 167 CYS 167 149 149 CYS CYS C . n 
C 3 168 ARG 168 150 150 ARG ARG C . n 
C 3 169 PHE 169 151 151 PHE PHE C . n 
C 3 170 LEU 170 152 152 LEU LEU C . n 
C 3 171 ASP 171 153 153 ASP ASP C . n 
C 3 172 ASP 172 154 154 ASP ASP C . n 
C 3 173 ASN 173 155 155 ASN ASN C . n 
C 3 174 GLN 174 156 156 GLN GLN C . n 
C 3 175 ILE 175 157 157 ILE ILE C . n 
C 3 176 VAL 176 158 158 VAL VAL C . n 
C 3 177 THR 177 159 159 THR THR C . n 
C 3 178 SER 178 160 160 SER SER C . n 
C 3 179 SER 179 161 161 SER SER C . n 
C 3 180 GLY 180 162 162 GLY GLY C . n 
C 3 181 ASP 181 163 163 ASP ASP C . n 
C 3 182 THR 182 164 164 THR THR C . n 
C 3 183 THR 183 165 165 THR THR C . n 
C 3 184 CYS 184 166 166 CYS CYS C . n 
C 3 185 ALA 185 167 167 ALA ALA C . n 
C 3 186 LEU 186 168 168 LEU LEU C . n 
C 3 187 TRP 187 169 169 TRP TRP C . n 
C 3 188 ASP 188 170 170 ASP ASP C . n 
C 3 189 ILE 189 171 171 ILE ILE C . n 
C 3 190 GLU 190 172 172 GLU GLU C . n 
C 3 191 THR 191 173 173 THR THR C . n 
C 3 192 GLY 192 174 174 GLY GLY C . n 
C 3 193 GLN 193 175 175 GLN GLN C . n 
C 3 194 GLN 194 176 176 GLN GLN C . n 
C 3 195 THR 195 177 177 THR THR C . n 
C 3 196 THR 196 178 178 THR THR C . n 
C 3 197 THR 197 179 179 THR THR C . n 
C 3 198 PHE 198 180 180 PHE PHE C . n 
C 3 199 THR 199 181 181 THR THR C . n 
C 3 200 GLY 200 182 182 GLY GLY C . n 
C 3 201 HIS 201 183 183 HIS HIS C . n 
C 3 202 THR 202 184 184 THR THR C . n 
C 3 203 GLY 203 185 185 GLY GLY C . n 
C 3 204 ASP 204 186 186 ASP ASP C . n 
C 3 205 VAL 205 187 187 VAL VAL C . n 
C 3 206 MET 206 188 188 MET MET C . n 
C 3 207 SER 207 189 189 SER SER C . n 
C 3 208 LEU 208 190 190 LEU LEU C . n 
C 3 209 SER 209 191 191 SER SER C . n 
C 3 210 LEU 210 192 192 LEU LEU C . n 
C 3 211 ALA 211 193 193 ALA ALA C . n 
C 3 212 PRO 212 194 194 PRO PRO C . n 
C 3 213 ASP 213 195 195 ASP ASP C . n 
C 3 214 THR 214 196 196 THR THR C . n 
C 3 215 ARG 215 197 197 ARG ARG C . n 
C 3 216 LEU 216 198 198 LEU LEU C . n 
C 3 217 PHE 217 199 199 PHE PHE C . n 
C 3 218 VAL 218 200 200 VAL VAL C . n 
C 3 219 SER 219 201 201 SER SER C . n 
C 3 220 GLY 220 202 202 GLY GLY C . n 
C 3 221 ALA 221 203 203 ALA ALA C . n 
C 3 222 CYS 222 204 204 CYS CYS C . n 
C 3 223 ASP 223 205 205 ASP ASP C . n 
C 3 224 ALA 224 206 206 ALA ALA C . n 
C 3 225 SER 225 207 207 SER SER C . n 
C 3 226 ALA 226 208 208 ALA ALA C . n 
C 3 227 LYS 227 209 209 LYS LYS C . n 
C 3 228 LEU 228 210 210 LEU LEU C . n 
C 3 229 TRP 229 211 211 TRP TRP C . n 
C 3 230 ASP 230 212 212 ASP ASP C . n 
C 3 231 VAL 231 213 213 VAL VAL C . n 
C 3 232 ARG 232 214 214 ARG ARG C . n 
C 3 233 GLU 233 215 215 GLU GLU C . n 
C 3 234 GLY 234 216 216 GLY GLY C . n 
C 3 235 MET 235 217 217 MET MET C . n 
C 3 236 CYS 236 218 218 CYS CYS C . n 
C 3 237 ARG 237 219 219 ARG ARG C . n 
C 3 238 GLN 238 220 220 GLN GLN C . n 
C 3 239 THR 239 221 221 THR THR C . n 
C 3 240 PHE 240 222 222 PHE PHE C . n 
C 3 241 THR 241 223 223 THR THR C . n 
C 3 242 GLY 242 224 224 GLY GLY C . n 
C 3 243 HIS 243 225 225 HIS HIS C . n 
C 3 244 GLU 244 226 226 GLU GLU C . n 
C 3 245 SER 245 227 227 SER SER C . n 
C 3 246 ASP 246 228 228 ASP ASP C . n 
C 3 247 ILE 247 229 229 ILE ILE C . n 
C 3 248 ASN 248 230 230 ASN ASN C . n 
C 3 249 ALA 249 231 231 ALA ALA C . n 
C 3 250 ILE 250 232 232 ILE ILE C . n 
C 3 251 CYS 251 233 233 CYS CYS C . n 
C 3 252 PHE 252 234 234 PHE PHE C . n 
C 3 253 PHE 253 235 235 PHE PHE C . n 
C 3 254 PRO 254 236 236 PRO PRO C . n 
C 3 255 ASN 255 237 237 ASN ASN C . n 
C 3 256 GLY 256 238 238 GLY GLY C . n 
C 3 257 ASN 257 239 239 ASN ASN C . n 
C 3 258 ALA 258 240 240 ALA ALA C . n 
C 3 259 PHE 259 241 241 PHE PHE C . n 
C 3 260 ALA 260 242 242 ALA ALA C . n 
C 3 261 THR 261 243 243 THR THR C . n 
C 3 262 GLY 262 244 244 GLY GLY C . n 
C 3 263 SER 263 245 245 SER SER C . n 
C 3 264 ASP 264 246 246 ASP ASP C . n 
C 3 265 ASP 265 247 247 ASP ASP C . n 
C 3 266 ALA 266 248 248 ALA ALA C . n 
C 3 267 THR 267 249 249 THR THR C . n 
C 3 268 CYS 268 250 250 CYS CYS C . n 
C 3 269 ARG 269 251 251 ARG ARG C . n 
C 3 270 LEU 270 252 252 LEU LEU C . n 
C 3 271 PHE 271 253 253 PHE PHE C . n 
C 3 272 ASP 272 254 254 ASP ASP C . n 
C 3 273 LEU 273 255 255 LEU LEU C . n 
C 3 274 ARG 274 256 256 ARG ARG C . n 
C 3 275 ALA 275 257 257 ALA ALA C . n 
C 3 276 ASP 276 258 258 ASP ASP C . n 
C 3 277 GLN 277 259 259 GLN GLN C . n 
C 3 278 GLU 278 260 260 GLU GLU C . n 
C 3 279 LEU 279 261 261 LEU LEU C . n 
C 3 280 MET 280 262 262 MET MET C . n 
C 3 281 THR 281 263 263 THR THR C . n 
C 3 282 TYR 282 264 264 TYR TYR C . n 
C 3 283 SER 283 265 265 SER SER C . n 
C 3 284 HIS 284 266 266 HIS HIS C . n 
C 3 285 ASP 285 267 267 ASP ASP C . n 
C 3 286 ASN 286 268 268 ASN ASN C . n 
C 3 287 ILE 287 269 269 ILE ILE C . n 
C 3 288 ILE 288 270 270 ILE ILE C . n 
C 3 289 CYS 289 271 271 CYS CYS C . n 
C 3 290 GLY 290 272 272 GLY GLY C . n 
C 3 291 ILE 291 273 273 ILE ILE C . n 
C 3 292 THR 292 274 274 THR THR C . n 
C 3 293 SER 293 275 275 SER SER C . n 
C 3 294 VAL 294 276 276 VAL VAL C . n 
C 3 295 SER 295 277 277 SER SER C . n 
C 3 296 PHE 296 278 278 PHE PHE C . n 
C 3 297 SER 297 279 279 SER SER C . n 
C 3 298 LYS 298 280 280 LYS LYS C . n 
C 3 299 SER 299 281 281 SER SER C . n 
C 3 300 GLY 300 282 282 GLY GLY C . n 
C 3 301 ARG 301 283 283 ARG ARG C . n 
C 3 302 LEU 302 284 284 LEU LEU C . n 
C 3 303 LEU 303 285 285 LEU LEU C . n 
C 3 304 LEU 304 286 286 LEU LEU C . n 
C 3 305 ALA 305 287 287 ALA ALA C . n 
C 3 306 GLY 306 288 288 GLY GLY C . n 
C 3 307 TYR 307 289 289 TYR TYR C . n 
C 3 308 ASP 308 290 290 ASP ASP C . n 
C 3 309 ASP 309 291 291 ASP ASP C . n 
C 3 310 PHE 310 292 292 PHE PHE C . n 
C 3 311 ASN 311 293 293 ASN ASN C . n 
C 3 312 CYS 312 294 294 CYS CYS C . n 
C 3 313 ASN 313 295 295 ASN ASN C . n 
C 3 314 VAL 314 296 296 VAL VAL C . n 
C 3 315 TRP 315 297 297 TRP TRP C . n 
C 3 316 ASP 316 298 298 ASP ASP C . n 
C 3 317 ALA 317 299 299 ALA ALA C . n 
C 3 318 LEU 318 300 300 LEU LEU C . n 
C 3 319 LYS 319 301 301 LYS LYS C . n 
C 3 320 ALA 320 302 302 ALA ALA C . n 
C 3 321 ASP 321 303 303 ASP ASP C . n 
C 3 322 ARG 322 304 304 ARG ARG C . n 
C 3 323 ALA 323 305 305 ALA ALA C . n 
C 3 324 GLY 324 306 306 GLY GLY C . n 
C 3 325 VAL 325 307 307 VAL VAL C . n 
C 3 326 LEU 326 308 308 LEU LEU C . n 
C 3 327 ALA 327 309 309 ALA ALA C . n 
C 3 328 GLY 328 310 310 GLY GLY C . n 
C 3 329 HIS 329 311 311 HIS HIS C . n 
C 3 330 ASP 330 312 312 ASP ASP C . n 
C 3 331 ASN 331 313 313 ASN ASN C . n 
C 3 332 ARG 332 314 314 ARG ARG C . n 
C 3 333 VAL 333 315 315 VAL VAL C . n 
C 3 334 SER 334 316 316 SER SER C . n 
C 3 335 CYS 335 317 317 CYS CYS C . n 
C 3 336 LEU 336 318 318 LEU LEU C . n 
C 3 337 GLY 337 319 319 GLY GLY C . n 
C 3 338 VAL 338 320 320 VAL VAL C . n 
C 3 339 THR 339 321 321 THR THR C . n 
C 3 340 ASP 340 322 322 ASP ASP C . n 
C 3 341 ASP 341 323 323 ASP ASP C . n 
C 3 342 GLY 342 324 324 GLY GLY C . n 
C 3 343 MET 343 325 325 MET MET C . n 
C 3 344 ALA 344 326 326 ALA ALA C . n 
C 3 345 VAL 345 327 327 VAL VAL C . n 
C 3 346 ALA 346 328 328 ALA ALA C . n 
C 3 347 THR 347 329 329 THR THR C . n 
C 3 348 GLY 348 330 330 GLY GLY C . n 
C 3 349 SER 349 331 331 SER SER C . n 
C 3 350 TRP 350 332 332 TRP TRP C . n 
C 3 351 ASP 351 333 333 ASP ASP C . n 
C 3 352 SER 352 334 334 SER SER C . n 
C 3 353 PHE 353 335 335 PHE PHE C . n 
C 3 354 LEU 354 336 336 LEU LEU C . n 
C 3 355 LYS 355 337 337 LYS LYS C . n 
C 3 356 ILE 356 338 338 ILE ILE C . n 
C 3 357 TRP 357 339 339 TRP TRP C . n 
C 3 358 ASN 358 340 340 ASN ASN C . n 
D 4 1   MET 1   1   ?   ?   ?   D . n 
D 4 2   ALA 2   2   ?   ?   ?   D . n 
D 4 3   SER 3   3   ?   ?   ?   D . n 
D 4 4   ASN 4   4   ?   ?   ?   D . n 
D 4 5   ASN 5   5   ?   ?   ?   D . n 
D 4 6   THR 6   6   ?   ?   ?   D . n 
D 4 7   ALA 7   7   ?   ?   ?   D . n 
D 4 8   SER 8   8   ?   ?   ?   D . n 
D 4 9   ILE 9   9   9   ILE ILE D . n 
D 4 10  ALA 10  10  10  ALA ALA D . n 
D 4 11  GLN 11  11  11  GLN GLN D . n 
D 4 12  ALA 12  12  12  ALA ALA D . n 
D 4 13  ARG 13  13  13  ARG ARG D . n 
D 4 14  LYS 14  14  14  LYS LYS D . n 
D 4 15  LEU 15  15  15  LEU LEU D . n 
D 4 16  VAL 16  16  16  VAL VAL D . n 
D 4 17  GLU 17  17  17  GLU GLU D . n 
D 4 18  GLN 18  18  18  GLN GLN D . n 
D 4 19  LEU 19  19  19  LEU LEU D . n 
D 4 20  LYS 20  20  20  LYS LYS D . n 
D 4 21  MET 21  21  21  MET MET D . n 
D 4 22  GLU 22  22  22  GLU GLU D . n 
D 4 23  ALA 23  23  23  ALA ALA D . n 
D 4 24  ASN 24  24  24  ASN ASN D . n 
D 4 25  ILE 25  25  25  ILE ILE D . n 
D 4 26  ASP 26  26  26  ASP ASP D . n 
D 4 27  ARG 27  27  27  ARG ARG D . n 
D 4 28  ILE 28  28  28  ILE ILE D . n 
D 4 29  LYS 29  29  29  LYS LYS D . n 
D 4 30  VAL 30  30  30  VAL VAL D . n 
D 4 31  SER 31  31  31  SER SER D . n 
D 4 32  LYS 32  32  32  LYS LYS D . n 
D 4 33  ALA 33  33  33  ALA ALA D . n 
D 4 34  ALA 34  34  34  ALA ALA D . n 
D 4 35  ALA 35  35  35  ALA ALA D . n 
D 4 36  ASP 36  36  36  ASP ASP D . n 
D 4 37  LEU 37  37  37  LEU LEU D . n 
D 4 38  MET 38  38  38  MET MET D . n 
D 4 39  ALA 39  39  39  ALA ALA D . n 
D 4 40  TYR 40  40  40  TYR TYR D . n 
D 4 41  CYS 41  41  41  CYS CYS D . n 
D 4 42  GLU 42  42  42  GLU GLU D . n 
D 4 43  ALA 43  43  43  ALA ALA D . n 
D 4 44  HIS 44  44  44  HIS HIS D . n 
D 4 45  ALA 45  45  45  ALA ALA D . n 
D 4 46  LYS 46  46  46  LYS LYS D . n 
D 4 47  GLU 47  47  47  GLU GLU D . n 
D 4 48  ASP 48  48  48  ASP ASP D . n 
D 4 49  PRO 49  49  49  PRO PRO D . n 
D 4 50  LEU 50  50  50  LEU LEU D . n 
D 4 51  LEU 51  51  51  LEU LEU D . n 
D 4 52  THR 52  52  52  THR THR D . n 
D 4 53  PRO 53  53  53  PRO PRO D . n 
D 4 54  VAL 54  54  54  VAL VAL D . n 
D 4 55  PRO 55  55  55  PRO PRO D . n 
D 4 56  ALA 56  56  56  ALA ALA D . n 
D 4 57  SER 57  57  57  SER SER D . n 
D 4 58  GLU 58  58  58  GLU GLU D . n 
D 4 59  ASN 59  59  59  ASN ASN D . n 
D 4 60  PRO 60  60  60  PRO PRO D . n 
D 4 61  PHE 61  61  61  PHE PHE D . n 
D 4 62  ARG 62  62  ?   ?   ?   D . n 
D 4 63  GLU 63  63  ?   ?   ?   D . n 
D 4 64  LYS 64  64  ?   ?   ?   D . n 
D 4 65  LYS 65  65  ?   ?   ?   D . n 
D 4 66  PHE 66  66  ?   ?   ?   D . n 
D 4 67  PHE 67  67  ?   ?   ?   D . n 
D 4 68  CYS 68  68  ?   ?   ?   D . n 
D 4 69  ALA 69  69  ?   ?   ?   D . n 
D 4 70  ILE 70  70  ?   ?   ?   D . n 
D 4 71  LEU 71  71  ?   ?   ?   D . n 
E 5 1   ASP 1   1   ?   ?   ?   E . n 
E 5 2   VAL 2   2   2   VAL VAL E . n 
E 5 3   GLN 3   3   3   GLN GLN E . n 
E 5 4   LEU 4   4   4   LEU LEU E . n 
E 5 5   VAL 5   5   5   VAL VAL E . n 
E 5 6   GLU 6   6   6   GLU GLU E . n 
E 5 7   SER 7   7   7   SER SER E . n 
E 5 8   GLY 8   8   8   GLY GLY E . n 
E 5 9   GLY 9   9   9   GLY GLY E . n 
E 5 10  GLY 10  10  10  GLY GLY E . n 
E 5 11  LEU 11  11  11  LEU LEU E . n 
E 5 12  VAL 12  12  12  VAL VAL E . n 
E 5 13  GLN 13  13  13  GLN GLN E . n 
E 5 14  PRO 14  14  14  PRO PRO E . n 
E 5 15  GLY 15  15  15  GLY GLY E . n 
E 5 16  GLY 16  16  16  GLY GLY E . n 
E 5 17  SER 17  17  17  SER SER E . n 
E 5 18  ARG 18  18  18  ARG ARG E . n 
E 5 19  LYS 19  19  19  LYS LYS E . n 
E 5 20  LEU 20  20  20  LEU LEU E . n 
E 5 21  SER 21  21  21  SER SER E . n 
E 5 22  CYS 22  22  22  CYS CYS E . n 
E 5 23  SER 23  23  23  SER SER E . n 
E 5 24  ALA 24  24  24  ALA ALA E . n 
E 5 25  SER 25  25  25  SER SER E . n 
E 5 26  GLY 26  26  26  GLY GLY E . n 
E 5 27  PHE 27  27  27  PHE PHE E . n 
E 5 28  ALA 28  28  28  ALA ALA E . n 
E 5 29  PHE 29  29  29  PHE PHE E . n 
E 5 30  SER 30  30  30  SER SER E . n 
E 5 31  SER 31  31  31  SER SER E . n 
E 5 32  PHE 32  32  32  PHE PHE E . n 
E 5 33  GLY 33  33  33  GLY GLY E . n 
E 5 34  MET 34  34  34  MET MET E . n 
E 5 35  HIS 35  35  35  HIS HIS E . n 
E 5 36  TRP 36  36  ?   ?   ?   E . n 
E 5 37  VAL 37  37  37  VAL VAL E . n 
E 5 38  ARG 38  38  38  ARG ARG E . n 
E 5 39  GLN 39  39  39  GLN GLN E . n 
E 5 40  ALA 40  40  40  ALA ALA E . n 
E 5 41  PRO 41  41  41  PRO PRO E . n 
E 5 42  GLU 42  42  42  GLU GLU E . n 
E 5 43  LYS 43  43  43  LYS LYS E . n 
E 5 44  GLY 44  44  44  GLY GLY E . n 
E 5 45  LEU 45  45  45  LEU LEU E . n 
E 5 46  GLU 46  46  46  GLU GLU E . n 
E 5 47  TRP 47  47  47  TRP TRP E . n 
E 5 48  VAL 48  48  48  VAL VAL E . n 
E 5 49  ALA 49  49  49  ALA ALA E . n 
E 5 50  TYR 50  50  50  TYR TYR E . n 
E 5 51  ILE 51  51  51  ILE ILE E . n 
E 5 52  SER 52  52  52  SER SER E . n 
E 5 53  SER 53  53  53  SER SER E . n 
E 5 54  GLY 54  54  54  GLY GLY E . n 
E 5 55  SER 55  55  55  SER SER E . n 
E 5 56  GLY 56  56  56  GLY GLY E . n 
E 5 57  THR 57  57  57  THR THR E . n 
E 5 58  ILE 58  58  58  ILE ILE E . n 
E 5 59  TYR 59  59  59  TYR TYR E . n 
E 5 60  TYR 60  60  60  TYR TYR E . n 
E 5 61  ALA 61  61  61  ALA ALA E . n 
E 5 62  ASP 62  62  62  ASP ASP E . n 
E 5 63  THR 63  63  63  THR THR E . n 
E 5 64  VAL 64  64  64  VAL VAL E . n 
E 5 65  LYS 65  65  65  LYS LYS E . n 
E 5 66  GLY 66  66  66  GLY GLY E . n 
E 5 67  ARG 67  67  67  ARG ARG E . n 
E 5 68  PHE 68  68  68  PHE PHE E . n 
E 5 69  THR 69  69  69  THR THR E . n 
E 5 70  ILE 70  70  70  ILE ILE E . n 
E 5 71  SER 71  71  71  SER SER E . n 
E 5 72  ARG 72  72  72  ARG ARG E . n 
E 5 73  ASP 73  73  73  ASP ASP E . n 
E 5 74  ASP 74  74  74  ASP ASP E . n 
E 5 75  PRO 75  75  75  PRO PRO E . n 
E 5 76  LYS 76  76  76  LYS LYS E . n 
E 5 77  ASN 77  77  77  ASN ASN E . n 
E 5 78  THR 78  78  78  THR THR E . n 
E 5 79  LEU 79  79  79  LEU LEU E . n 
E 5 80  PHE 80  80  80  PHE PHE E . n 
E 5 81  LEU 81  81  81  LEU LEU E . n 
E 5 82  GLN 82  82  82  GLN GLN E . n 
E 5 83  MET 83  83  83  MET MET E . n 
E 5 84  THR 84  84  84  THR THR E . n 
E 5 85  SER 85  85  85  SER SER E . n 
E 5 86  LEU 86  86  86  LEU LEU E . n 
E 5 87  ARG 87  87  87  ARG ARG E . n 
E 5 88  SER 88  88  88  SER SER E . n 
E 5 89  GLU 89  89  89  GLU GLU E . n 
E 5 90  ASP 90  90  90  ASP ASP E . n 
E 5 91  THR 91  91  91  THR THR E . n 
E 5 92  ALA 92  92  92  ALA ALA E . n 
E 5 93  MET 93  93  93  MET MET E . n 
E 5 94  TYR 94  94  94  TYR TYR E . n 
E 5 95  TYR 95  95  95  TYR TYR E . n 
E 5 96  CYS 96  96  96  CYS CYS E . n 
E 5 97  VAL 97  97  97  VAL VAL E . n 
E 5 98  ARG 98  98  98  ARG ARG E . n 
E 5 99  SER 99  99  99  SER SER E . n 
E 5 100 ILE 100 100 100 ILE ILE E . n 
E 5 101 TYR 101 101 101 TYR TYR E . n 
E 5 102 TYR 102 102 102 TYR TYR E . n 
E 5 103 TYR 103 103 103 TYR TYR E . n 
E 5 104 GLY 104 104 104 GLY GLY E . n 
E 5 105 SER 105 105 105 SER SER E . n 
E 5 106 SER 106 106 106 SER SER E . n 
E 5 107 PRO 107 107 107 PRO PRO E . n 
E 5 108 PHE 108 108 108 PHE PHE E . n 
E 5 109 ASP 109 109 109 ASP ASP E . n 
E 5 110 PHE 110 110 110 PHE PHE E . n 
E 5 111 TRP 111 111 111 TRP TRP E . n 
E 5 112 GLY 112 112 112 GLY GLY E . n 
E 5 113 GLN 113 113 113 GLN GLN E . n 
E 5 114 GLY 114 114 114 GLY GLY E . n 
E 5 115 THR 115 115 115 THR THR E . n 
E 5 116 THR 116 116 116 THR THR E . n 
E 5 117 LEU 117 117 117 LEU LEU E . n 
E 5 118 THR 118 118 118 THR THR E . n 
E 5 119 VAL 119 119 119 VAL VAL E . n 
E 5 120 SER 120 119 ?   ?   ?   E A n 
E 5 121 SER 121 119 ?   ?   ?   E B n 
E 5 122 GLY 122 119 ?   ?   ?   E C n 
E 5 123 GLY 123 119 ?   ?   ?   E D n 
E 5 124 GLY 124 119 ?   ?   ?   E E n 
E 5 125 GLY 125 119 ?   ?   ?   E F n 
E 5 126 SER 126 119 ?   ?   ?   E G n 
E 5 127 GLY 127 119 ?   ?   ?   E H n 
E 5 128 GLY 128 119 ?   ?   ?   E I n 
E 5 129 GLY 129 119 ?   ?   ?   E J n 
E 5 130 GLY 130 119 ?   ?   ?   E K n 
E 5 131 SER 131 119 ?   ?   ?   E L n 
E 5 132 GLY 132 119 ?   ?   ?   E M n 
E 5 133 GLY 133 119 ?   ?   ?   E N n 
E 5 134 GLY 134 119 ?   ?   ?   E O n 
E 5 135 GLY 135 119 ?   ?   ?   E P n 
E 5 136 SER 136 119 ?   ?   ?   E Q n 
E 5 137 ASP 137 125 125 ASP ASP E . n 
E 5 138 ILE 138 126 126 ILE ILE E . n 
E 5 139 VAL 139 127 127 VAL VAL E . n 
E 5 140 MET 140 128 128 MET MET E . n 
E 5 141 THR 141 129 129 THR THR E . n 
E 5 142 GLN 142 130 130 GLN GLN E . n 
E 5 143 ALA 143 131 131 ALA ALA E . n 
E 5 144 THR 144 132 132 THR THR E . n 
E 5 145 SER 145 133 133 SER SER E . n 
E 5 146 SER 146 134 134 SER SER E . n 
E 5 147 VAL 147 135 135 VAL VAL E . n 
E 5 148 PRO 148 136 136 PRO PRO E . n 
E 5 149 VAL 149 137 137 VAL VAL E . n 
E 5 150 THR 150 138 138 THR THR E . n 
E 5 151 PRO 151 139 139 PRO PRO E . n 
E 5 152 GLY 152 140 140 GLY GLY E . n 
E 5 153 GLU 153 141 141 GLU GLU E . n 
E 5 154 SER 154 142 142 SER SER E . n 
E 5 155 VAL 155 143 143 VAL VAL E . n 
E 5 156 SER 156 144 144 SER SER E . n 
E 5 157 ILE 157 145 145 ILE ILE E . n 
E 5 158 SER 158 146 146 SER SER E . n 
E 5 159 CYS 159 147 147 CYS CYS E . n 
E 5 160 ARG 160 148 148 ARG ARG E . n 
E 5 161 SER 161 149 149 SER SER E . n 
E 5 162 SER 162 150 150 SER SER E . n 
E 5 163 LYS 163 151 151 LYS LYS E . n 
E 5 164 SER 164 152 152 SER SER E . n 
E 5 165 LEU 165 153 153 LEU LEU E . n 
E 5 166 LEU 166 154 154 LEU LEU E . n 
E 5 167 HIS 167 155 155 HIS HIS E . n 
E 5 168 SER 168 156 156 SER SER E . n 
E 5 169 ASN 169 157 157 ASN ASN E . n 
E 5 170 GLY 170 158 158 GLY GLY E . n 
E 5 171 ASN 171 159 159 ASN ASN E . n 
E 5 172 THR 172 160 160 THR THR E . n 
E 5 173 TYR 173 161 161 TYR TYR E . n 
E 5 174 LEU 174 162 162 LEU LEU E . n 
E 5 175 TYR 175 163 163 TYR TYR E . n 
E 5 176 TRP 176 164 164 TRP TRP E . n 
E 5 177 PHE 177 165 165 PHE PHE E . n 
E 5 178 LEU 178 166 166 LEU LEU E . n 
E 5 179 GLN 179 167 167 GLN GLN E . n 
E 5 180 ARG 180 168 168 ARG ARG E . n 
E 5 181 PRO 181 169 169 PRO PRO E . n 
E 5 182 GLY 182 170 170 GLY GLY E . n 
E 5 183 GLN 183 171 171 GLN GLN E . n 
E 5 184 SER 184 172 172 SER SER E . n 
E 5 185 PRO 185 173 173 PRO PRO E . n 
E 5 186 GLN 186 174 174 GLN GLN E . n 
E 5 187 LEU 187 175 175 LEU LEU E . n 
E 5 188 LEU 188 176 176 LEU LEU E . n 
E 5 189 ILE 189 177 177 ILE ILE E . n 
E 5 190 TYR 190 178 178 TYR TYR E . n 
E 5 191 ARG 191 179 179 ARG ARG E . n 
E 5 192 MET 192 180 180 MET MET E . n 
E 5 193 SER 193 181 181 SER SER E . n 
E 5 194 ASN 194 182 182 ASN ASN E . n 
E 5 195 LEU 195 183 183 LEU LEU E . n 
E 5 196 ALA 196 184 184 ALA ALA E . n 
E 5 197 SER 197 185 185 SER SER E . n 
E 5 198 GLY 198 186 186 GLY GLY E . n 
E 5 199 VAL 199 187 187 VAL VAL E . n 
E 5 200 PRO 200 188 188 PRO PRO E . n 
E 5 201 ASP 201 189 189 ASP ASP E . n 
E 5 202 ARG 202 190 190 ARG ARG E . n 
E 5 203 PHE 203 191 191 PHE PHE E . n 
E 5 204 SER 204 192 192 SER SER E . n 
E 5 205 GLY 205 193 193 GLY GLY E . n 
E 5 206 SER 206 194 194 SER SER E . n 
E 5 207 GLY 207 195 195 GLY GLY E . n 
E 5 208 SER 208 196 196 SER SER E . n 
E 5 209 GLY 209 197 197 GLY GLY E . n 
E 5 210 THR 210 198 198 THR THR E . n 
E 5 211 ALA 211 199 199 ALA ALA E . n 
E 5 212 PHE 212 200 200 PHE PHE E . n 
E 5 213 THR 213 201 201 THR THR E . n 
E 5 214 LEU 214 202 202 LEU LEU E . n 
E 5 215 THR 215 203 203 THR THR E . n 
E 5 216 ILE 216 204 204 ILE ILE E . n 
E 5 217 SER 217 205 205 SER SER E . n 
E 5 218 ARG 218 206 206 ARG ARG E . n 
E 5 219 LEU 219 207 207 LEU LEU E . n 
E 5 220 GLU 220 208 208 GLU GLU E . n 
E 5 221 ALA 221 209 209 ALA ALA E . n 
E 5 222 GLU 222 210 210 GLU GLU E . n 
E 5 223 ASP 223 211 211 ASP ASP E . n 
E 5 224 VAL 224 212 212 VAL VAL E . n 
E 5 225 GLY 225 213 213 GLY GLY E . n 
E 5 226 VAL 226 214 214 VAL VAL E . n 
E 5 227 TYR 227 215 215 TYR TYR E . n 
E 5 228 TYR 228 216 216 TYR TYR E . n 
E 5 229 CYS 229 217 217 CYS CYS E . n 
E 5 230 MET 230 218 218 MET MET E . n 
E 5 231 GLN 231 219 219 GLN GLN E . n 
E 5 232 HIS 232 220 220 HIS HIS E . n 
E 5 233 LEU 233 221 221 LEU LEU E . n 
E 5 234 GLU 234 222 222 GLU GLU E . n 
E 5 235 TYR 235 223 223 TYR TYR E . n 
E 5 236 PRO 236 224 224 PRO PRO E . n 
E 5 237 LEU 237 225 225 LEU LEU E . n 
E 5 238 THR 238 226 226 THR THR E . n 
E 5 239 PHE 239 227 227 PHE PHE E . n 
E 5 240 GLY 240 228 228 GLY GLY E . n 
E 5 241 ALA 241 229 229 ALA ALA E . n 
E 5 242 GLY 242 230 230 GLY GLY E . n 
E 5 243 THR 243 231 231 THR THR E . n 
E 5 244 LYS 244 232 232 LYS LYS E . n 
E 5 245 LEU 245 233 233 LEU LEU E . n 
E 5 246 GLU 246 234 234 GLU GLU E . n 
E 5 247 LEU 247 235 235 LEU LEU E . n 
E 5 248 LYS 248 236 ?   ?   ?   E . n 
E 5 249 ALA 249 237 ?   ?   ?   E . n 
E 5 250 ALA 250 238 ?   ?   ?   E . n 
E 5 251 ALA 251 239 ?   ?   ?   E . n 
E 5 252 LEU 252 240 ?   ?   ?   E . n 
E 5 253 GLU 253 241 ?   ?   ?   E . n 
E 5 254 VAL 254 242 ?   ?   ?   E . n 
E 5 255 LEU 255 243 ?   ?   ?   E . n 
E 5 256 PHE 256 244 ?   ?   ?   E . n 
E 5 257 GLN 257 245 ?   ?   ?   E . n 
E 5 258 GLY 258 246 ?   ?   ?   E . n 
E 5 259 PRO 259 247 ?   ?   ?   E . n 
E 5 260 HIS 260 248 ?   ?   ?   E . n 
E 5 261 HIS 261 249 ?   ?   ?   E . n 
E 5 262 HIS 262 250 ?   ?   ?   E . n 
E 5 263 HIS 263 251 ?   ?   ?   E . n 
E 5 264 HIS 264 252 ?   ?   ?   E . n 
E 5 265 HIS 265 253 ?   ?   ?   E . n 
E 5 266 HIS 266 254 ?   ?   ?   E . n 
E 5 267 HIS 267 255 ?   ?   ?   E . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        SRO 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   SRO 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          SRO 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      SRO 
_pdbx_nonpoly_scheme.auth_mon_id     SEO 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A LEU 80  ? CG  ? A LEU 80  CG  
2   1 Y 1 A LEU 80  ? CD1 ? A LEU 80  CD1 
3   1 Y 1 A LEU 80  ? CD2 ? A LEU 80  CD2 
4   1 Y 1 A VAL 83  ? CG1 ? A VAL 83  CG1 
5   1 Y 1 A VAL 83  ? CG2 ? A VAL 83  CG2 
6   1 Y 1 A ILE 86  ? CG1 ? A ILE 86  CG1 
7   1 Y 1 A ILE 86  ? CG2 ? A ILE 86  CG2 
8   1 Y 1 A ILE 86  ? CD1 ? A ILE 86  CD1 
9   1 Y 1 A LEU 87  ? CG  ? A LEU 87  CG  
10  1 Y 1 A LEU 87  ? CD1 ? A LEU 87  CD1 
11  1 Y 1 A LEU 87  ? CD2 ? A LEU 87  CD2 
12  1 Y 1 A ILE 89  ? CG1 ? A ILE 89  CG1 
13  1 Y 1 A ILE 89  ? CG2 ? A ILE 89  CG2 
14  1 Y 1 A ILE 89  ? CD1 ? A ILE 89  CD1 
15  1 Y 1 A ILE 93  ? CG1 ? A ILE 93  CG1 
16  1 Y 1 A ILE 93  ? CG2 ? A ILE 93  CG2 
17  1 Y 1 A ILE 93  ? CD1 ? A ILE 93  CD1 
18  1 Y 1 A MET 97  ? CG  ? A MET 97  CG  
19  1 Y 1 A MET 97  ? SD  ? A MET 97  SD  
20  1 Y 1 A MET 97  ? CE  ? A MET 97  CE  
21  1 Y 1 A GLU 102 ? CG  ? A GLU 102 CG  
22  1 Y 1 A GLU 102 ? CD  ? A GLU 102 CD  
23  1 Y 1 A GLU 102 ? OE1 ? A GLU 102 OE1 
24  1 Y 1 A GLU 102 ? OE2 ? A GLU 102 OE2 
25  1 Y 1 A LYS 103 ? CG  ? A LYS 103 CG  
26  1 Y 1 A LYS 103 ? CD  ? A LYS 103 CD  
27  1 Y 1 A LYS 103 ? CE  ? A LYS 103 CE  
28  1 Y 1 A LYS 103 ? NZ  ? A LYS 103 NZ  
29  1 Y 1 A LYS 104 ? CG  ? A LYS 104 CG  
30  1 Y 1 A LYS 104 ? CD  ? A LYS 104 CD  
31  1 Y 1 A LYS 104 ? CE  ? A LYS 104 CE  
32  1 Y 1 A LYS 104 ? NZ  ? A LYS 104 NZ  
33  1 Y 1 A GLN 106 ? CG  ? A GLN 106 CG  
34  1 Y 1 A GLN 106 ? CD  ? A GLN 106 CD  
35  1 Y 1 A GLN 106 ? OE1 ? A GLN 106 OE1 
36  1 Y 1 A GLN 106 ? NE2 ? A GLN 106 NE2 
37  1 Y 1 A ASN 107 ? CG  ? A ASN 107 CG  
38  1 Y 1 A ASN 107 ? OD1 ? A ASN 107 OD1 
39  1 Y 1 A ASN 107 ? ND2 ? A ASN 107 ND2 
40  1 Y 1 A TYR 111 ? CG  ? A TYR 111 CG  
41  1 Y 1 A TYR 111 ? CD1 ? A TYR 111 CD1 
42  1 Y 1 A TYR 111 ? CD2 ? A TYR 111 CD2 
43  1 Y 1 A TYR 111 ? CE1 ? A TYR 111 CE1 
44  1 Y 1 A TYR 111 ? CE2 ? A TYR 111 CE2 
45  1 Y 1 A TYR 111 ? CZ  ? A TYR 111 CZ  
46  1 Y 1 A TYR 111 ? OH  ? A TYR 111 OH  
47  1 Y 1 A PHE 125 ? CG  ? A PHE 125 CG  
48  1 Y 1 A PHE 125 ? CD1 ? A PHE 125 CD1 
49  1 Y 1 A PHE 125 ? CD2 ? A PHE 125 CD2 
50  1 Y 1 A PHE 125 ? CE1 ? A PHE 125 CE1 
51  1 Y 1 A PHE 125 ? CE2 ? A PHE 125 CE2 
52  1 Y 1 A PHE 125 ? CZ  ? A PHE 125 CZ  
53  1 Y 1 A LEU 136 ? CG  ? A LEU 136 CG  
54  1 Y 1 A LEU 136 ? CD1 ? A LEU 136 CD1 
55  1 Y 1 A LEU 136 ? CD2 ? A LEU 136 CD2 
56  1 Y 1 A TYR 139 ? CG  ? A TYR 139 CG  
57  1 Y 1 A TYR 139 ? CD1 ? A TYR 139 CD1 
58  1 Y 1 A TYR 139 ? CD2 ? A TYR 139 CD2 
59  1 Y 1 A TYR 139 ? CE1 ? A TYR 139 CE1 
60  1 Y 1 A TYR 139 ? CE2 ? A TYR 139 CE2 
61  1 Y 1 A TYR 139 ? CZ  ? A TYR 139 CZ  
62  1 Y 1 A TYR 139 ? OH  ? A TYR 139 OH  
63  1 Y 1 A ARG 140 ? CG  ? A ARG 140 CG  
64  1 Y 1 A ARG 140 ? CD  ? A ARG 140 CD  
65  1 Y 1 A ARG 140 ? NE  ? A ARG 140 NE  
66  1 Y 1 A ARG 140 ? CZ  ? A ARG 140 CZ  
67  1 Y 1 A ARG 140 ? NH1 ? A ARG 140 NH1 
68  1 Y 1 A ARG 140 ? NH2 ? A ARG 140 NH2 
69  1 Y 1 A LEU 143 ? CG  ? A LEU 143 CG  
70  1 Y 1 A LEU 143 ? CD1 ? A LEU 143 CD1 
71  1 Y 1 A LEU 143 ? CD2 ? A LEU 143 CD2 
72  1 Y 1 A LYS 146 ? CG  ? A LYS 146 CG  
73  1 Y 1 A LYS 146 ? CD  ? A LYS 146 CD  
74  1 Y 1 A LYS 146 ? CE  ? A LYS 146 CE  
75  1 Y 1 A LYS 146 ? NZ  ? A LYS 146 NZ  
76  1 Y 1 A ASN 187 ? CG  ? A ASN 187 CG  
77  1 Y 1 A ASN 187 ? OD1 ? A ASN 187 OD1 
78  1 Y 1 A ASN 187 ? ND2 ? A ASN 187 ND2 
79  1 Y 1 A SER 188 ? OG  ? A SER 188 OG  
80  1 Y 1 A ARG 189 ? CG  ? A ARG 189 CG  
81  1 Y 1 A ARG 189 ? CD  ? A ARG 189 CD  
82  1 Y 1 A ARG 189 ? NE  ? A ARG 189 NE  
83  1 Y 1 A ARG 189 ? CZ  ? A ARG 189 CZ  
84  1 Y 1 A ARG 189 ? NH1 ? A ARG 189 NH1 
85  1 Y 1 A ARG 189 ? NH2 ? A ARG 189 NH2 
86  1 Y 1 A LYS 195 ? CG  ? A LYS 195 CG  
87  1 Y 1 A LYS 195 ? CD  ? A LYS 195 CD  
88  1 Y 1 A LYS 195 ? CE  ? A LYS 195 CE  
89  1 Y 1 A LYS 195 ? NZ  ? A LYS 195 NZ  
90  1 Y 1 A MET 208 ? CG  ? A MET 208 CG  
91  1 Y 1 A MET 208 ? SD  ? A MET 208 SD  
92  1 Y 1 A MET 208 ? CE  ? A MET 208 CE  
93  1 Y 1 A ILE 210 ? CG1 ? A ILE 210 CG1 
94  1 Y 1 A ILE 210 ? CG2 ? A ILE 210 CG2 
95  1 Y 1 A ILE 210 ? CD1 ? A ILE 210 CD1 
96  1 Y 1 A GLN 216 ? CG  ? A GLN 216 CG  
97  1 Y 1 A GLN 216 ? CD  ? A GLN 216 CD  
98  1 Y 1 A GLN 216 ? OE1 ? A GLN 216 OE1 
99  1 Y 1 A GLN 216 ? NE2 ? A GLN 216 NE2 
100 1 Y 1 A ASP 217 ? CG  ? A ASP 217 CG  
101 1 Y 1 A ASP 217 ? OD1 ? A ASP 217 OD1 
102 1 Y 1 A ASP 217 ? OD2 ? A ASP 217 OD2 
103 1 Y 1 A ASP 218 ? CG  ? A ASP 218 CG  
104 1 Y 1 A ASP 218 ? OD1 ? A ASP 218 OD1 
105 1 Y 1 A ASP 218 ? OD2 ? A ASP 218 OD2 
106 1 Y 1 A SER 219 ? OG  ? A SER 219 OG  
107 1 Y 1 A LYS 220 ? CG  ? A LYS 220 CG  
108 1 Y 1 A LYS 220 ? CD  ? A LYS 220 CD  
109 1 Y 1 A LYS 220 ? CE  ? A LYS 220 CE  
110 1 Y 1 A LYS 220 ? NZ  ? A LYS 220 NZ  
111 1 Y 1 A LYS 223 ? CG  ? A LYS 223 CG  
112 1 Y 1 A LYS 223 ? CD  ? A LYS 223 CD  
113 1 Y 1 A LYS 223 ? CE  ? A LYS 223 CE  
114 1 Y 1 A LYS 223 ? NZ  ? A LYS 223 NZ  
115 1 Y 1 A GLU 224 ? CG  ? A GLU 224 CG  
116 1 Y 1 A GLU 224 ? CD  ? A GLU 224 CD  
117 1 Y 1 A GLU 224 ? OE1 ? A GLU 224 OE1 
118 1 Y 1 A GLU 224 ? OE2 ? A GLU 224 OE2 
119 1 Y 1 A LEU 228 ? CG  ? A LEU 228 CG  
120 1 Y 1 A LEU 228 ? CD1 ? A LEU 228 CD1 
121 1 Y 1 A LEU 228 ? CD2 ? A LEU 228 CD2 
122 1 Y 1 A ASP 231 ? CG  ? A ASP 231 CG  
123 1 Y 1 A ASP 231 ? OD1 ? A ASP 231 OD1 
124 1 Y 1 A ASP 231 ? OD2 ? A ASP 231 OD2 
125 1 Y 1 A ASP 232 ? CG  ? A ASP 232 CG  
126 1 Y 1 A ASP 232 ? OD1 ? A ASP 232 OD1 
127 1 Y 1 A ASP 232 ? OD2 ? A ASP 232 OD2 
128 1 Y 1 A ASN 233 ? CG  ? A ASN 233 CG  
129 1 Y 1 A ASN 233 ? OD1 ? A ASN 233 OD1 
130 1 Y 1 A ASN 233 ? ND2 ? A ASN 233 ND2 
131 1 Y 1 A ILE 237 ? CG1 ? A ILE 237 CG1 
132 1 Y 1 A ILE 237 ? CG2 ? A ILE 237 CG2 
133 1 Y 1 A ILE 237 ? CD1 ? A ILE 237 CD1 
134 1 Y 1 A ILE 245 ? CG1 ? A ILE 245 CG1 
135 1 Y 1 A ILE 245 ? CG2 ? A ILE 245 CG2 
136 1 Y 1 A ILE 245 ? CD1 ? A ILE 245 CD1 
137 1 Y 1 A GLN 262 ? CG  ? A GLN 262 CG  
138 1 Y 1 A GLN 262 ? CD  ? A GLN 262 CD  
139 1 Y 1 A GLN 262 ? OE1 ? A GLN 262 OE1 
140 1 Y 1 A GLN 262 ? NE2 ? A GLN 262 NE2 
141 1 Y 1 A ILE 315 ? CG1 ? A ILE 315 CG1 
142 1 Y 1 A ILE 315 ? CG2 ? A ILE 315 CG2 
143 1 Y 1 A ILE 315 ? CD1 ? A ILE 315 CD1 
144 1 Y 1 A LYS 320 ? CG  ? A LYS 320 CG  
145 1 Y 1 A LYS 320 ? CD  ? A LYS 320 CD  
146 1 Y 1 A LYS 320 ? CE  ? A LYS 320 CE  
147 1 Y 1 A LYS 320 ? NZ  ? A LYS 320 NZ  
148 1 Y 1 A LYS 323 ? CG  ? A LYS 323 CG  
149 1 Y 1 A LYS 323 ? CD  ? A LYS 323 CD  
150 1 Y 1 A LYS 323 ? CE  ? A LYS 323 CE  
151 1 Y 1 A LYS 323 ? NZ  ? A LYS 323 NZ  
152 1 Y 1 A MET 335 ? CG  ? A MET 335 CG  
153 1 Y 1 A MET 335 ? SD  ? A MET 335 SD  
154 1 Y 1 A MET 335 ? CE  ? A MET 335 CE  
155 1 Y 1 A MET 345 ? CG  ? A MET 345 CG  
156 1 Y 1 A MET 345 ? SD  ? A MET 345 SD  
157 1 Y 1 A MET 345 ? CE  ? A MET 345 CE  
158 1 Y 1 A VAL 347 ? CG1 ? A VAL 347 CG1 
159 1 Y 1 A VAL 347 ? CG2 ? A VAL 347 CG2 
160 1 Y 1 A ILE 348 ? CG1 ? A ILE 348 CG1 
161 1 Y 1 A ILE 348 ? CG2 ? A ILE 348 CG2 
162 1 Y 1 A ILE 348 ? CD1 ? A ILE 348 CD1 
163 1 Y 1 A ASP 356 ? CG  ? A ASP 356 CG  
164 1 Y 1 A ASP 356 ? OD1 ? A ASP 356 OD1 
165 1 Y 1 A ASP 356 ? OD2 ? A ASP 356 OD2 
166 1 Y 1 A VAL 357 ? CG1 ? A VAL 357 CG1 
167 1 Y 1 A VAL 357 ? CG2 ? A VAL 357 CG2 
168 1 Y 1 A PHE 383 ? CG  ? A PHE 383 CG  
169 1 Y 1 A PHE 383 ? CD1 ? A PHE 383 CD1 
170 1 Y 1 A PHE 383 ? CD2 ? A PHE 383 CD2 
171 1 Y 1 A PHE 383 ? CE1 ? A PHE 383 CE1 
172 1 Y 1 A PHE 383 ? CE2 ? A PHE 383 CE2 
173 1 Y 1 A PHE 383 ? CZ  ? A PHE 383 CZ  
174 1 Y 1 A LYS 385 ? CG  ? A LYS 385 CG  
175 1 Y 1 A LYS 385 ? CD  ? A LYS 385 CD  
176 1 Y 1 A LYS 385 ? CE  ? A LYS 385 CE  
177 1 Y 1 A LYS 385 ? NZ  ? A LYS 385 NZ  
178 1 Y 1 A SER 389 ? OG  ? A SER 389 OG  
179 1 Y 1 B GLN 52  ? CG  ? B GLN 52  CG  
180 1 Y 1 B GLN 52  ? CD  ? B GLN 52  CD  
181 1 Y 1 B GLN 52  ? OE1 ? B GLN 52  OE1 
182 1 Y 1 B GLN 52  ? NE2 ? B GLN 52  NE2 
183 1 Y 1 B PHE 70  ? CG  ? B PHE 70  CG  
184 1 Y 1 B PHE 70  ? CD1 ? B PHE 70  CD1 
185 1 Y 1 B PHE 70  ? CD2 ? B PHE 70  CD2 
186 1 Y 1 B PHE 70  ? CE1 ? B PHE 70  CE1 
187 1 Y 1 B PHE 70  ? CE2 ? B PHE 70  CE2 
188 1 Y 1 B PHE 70  ? CZ  ? B PHE 70  CZ  
189 1 Y 1 B LYS 78  ? CG  ? B LYS 78  CG  
190 1 Y 1 B LYS 78  ? CD  ? B LYS 78  CD  
191 1 Y 1 B LYS 78  ? CE  ? B LYS 78  CE  
192 1 Y 1 B LYS 78  ? NZ  ? B LYS 78  NZ  
193 1 Y 1 B ASP 91  ? CG  ? B ASP 91  CG  
194 1 Y 1 B ASP 91  ? OD1 ? B ASP 91  OD1 
195 1 Y 1 B ASP 91  ? OD2 ? B ASP 91  OD2 
196 1 Y 1 B ARG 94  ? CG  ? B ARG 94  CG  
197 1 Y 1 B ARG 94  ? CD  ? B ARG 94  CD  
198 1 Y 1 B ARG 94  ? NE  ? B ARG 94  NE  
199 1 Y 1 B ARG 94  ? CZ  ? B ARG 94  CZ  
200 1 Y 1 B ARG 94  ? NH1 ? B ARG 94  NH1 
201 1 Y 1 B ARG 94  ? NH2 ? B ARG 94  NH2 
202 1 Y 1 B ASP 111 ? CG  ? B ASP 111 CG  
203 1 Y 1 B ASP 111 ? OD1 ? B ASP 111 OD1 
204 1 Y 1 B ASP 111 ? OD2 ? B ASP 111 OD2 
205 1 Y 1 B GLU 120 ? CG  ? B GLU 120 CG  
206 1 Y 1 B GLU 120 ? CD  ? B GLU 120 CD  
207 1 Y 1 B GLU 120 ? OE1 ? B GLU 120 OE1 
208 1 Y 1 B GLU 120 ? OE2 ? B GLU 120 OE2 
209 1 Y 1 B LEU 148 ? CG  ? B LEU 148 CG  
210 1 Y 1 B LEU 148 ? CD1 ? B LEU 148 CD1 
211 1 Y 1 B LEU 148 ? CD2 ? B LEU 148 CD2 
212 1 Y 1 B LYS 157 ? CG  ? B LYS 157 CG  
213 1 Y 1 B LYS 157 ? CD  ? B LYS 157 CD  
214 1 Y 1 B LYS 157 ? CE  ? B LYS 157 CE  
215 1 Y 1 B LYS 157 ? NZ  ? B LYS 157 NZ  
216 1 Y 1 B GLU 161 ? CG  ? B GLU 161 CG  
217 1 Y 1 B GLU 161 ? CD  ? B GLU 161 CD  
218 1 Y 1 B GLU 161 ? OE1 ? B GLU 161 OE1 
219 1 Y 1 B GLU 161 ? OE2 ? B GLU 161 OE2 
220 1 Y 1 B GLU 174 ? CG  ? B GLU 174 CG  
221 1 Y 1 B GLU 174 ? CD  ? B GLU 174 CD  
222 1 Y 1 B GLU 174 ? OE1 ? B GLU 174 OE1 
223 1 Y 1 B GLU 174 ? OE2 ? B GLU 174 OE2 
224 1 Y 1 B GLU 179 ? CG  ? B GLU 179 CG  
225 1 Y 1 B GLU 179 ? CD  ? B GLU 179 CD  
226 1 Y 1 B GLU 179 ? OE1 ? B GLU 179 OE1 
227 1 Y 1 B GLU 179 ? OE2 ? B GLU 179 OE2 
228 1 Y 1 B LYS 195 ? CG  ? B LYS 195 CG  
229 1 Y 1 B LYS 195 ? CD  ? B LYS 195 CD  
230 1 Y 1 B LYS 195 ? CE  ? B LYS 195 CE  
231 1 Y 1 B LYS 195 ? NZ  ? B LYS 195 NZ  
232 1 Y 1 B ASP 206 ? CG  ? B ASP 206 CG  
233 1 Y 1 B ASP 206 ? OD1 ? B ASP 206 OD1 
234 1 Y 1 B ASP 206 ? OD2 ? B ASP 206 OD2 
235 1 Y 1 C LEU 4   ? CG  ? C LEU 22  CG  
236 1 Y 1 C LEU 4   ? CD1 ? C LEU 22  CD1 
237 1 Y 1 C LEU 4   ? CD2 ? C LEU 22  CD2 
238 1 Y 1 C ARG 8   ? CG  ? C ARG 26  CG  
239 1 Y 1 C ARG 8   ? CD  ? C ARG 26  CD  
240 1 Y 1 C ARG 8   ? NE  ? C ARG 26  NE  
241 1 Y 1 C ARG 8   ? CZ  ? C ARG 26  CZ  
242 1 Y 1 C ARG 8   ? NH1 ? C ARG 26  NH1 
243 1 Y 1 C ARG 8   ? NH2 ? C ARG 26  NH2 
244 1 Y 1 C GLU 10  ? CG  ? C GLU 28  CG  
245 1 Y 1 C GLU 10  ? CD  ? C GLU 28  CD  
246 1 Y 1 C GLU 10  ? OE1 ? C GLU 28  OE1 
247 1 Y 1 C GLU 10  ? OE2 ? C GLU 28  OE2 
248 1 Y 1 C GLU 12  ? CG  ? C GLU 30  CG  
249 1 Y 1 C GLU 12  ? CD  ? C GLU 30  CD  
250 1 Y 1 C GLU 12  ? OE1 ? C GLU 30  OE1 
251 1 Y 1 C GLU 12  ? OE2 ? C GLU 30  OE2 
252 1 Y 1 C ARG 19  ? CG  ? C ARG 37  CG  
253 1 Y 1 C ARG 19  ? CD  ? C ARG 37  CD  
254 1 Y 1 C ARG 19  ? NE  ? C ARG 37  NE  
255 1 Y 1 C ARG 19  ? CZ  ? C ARG 37  CZ  
256 1 Y 1 C ARG 19  ? NH1 ? C ARG 37  NH1 
257 1 Y 1 C ARG 19  ? NH2 ? C ARG 37  NH2 
258 1 Y 1 C ASN 35  ? CG  ? C ASN 53  CG  
259 1 Y 1 C ASN 35  ? OD1 ? C ASN 53  OD1 
260 1 Y 1 C ASN 35  ? ND2 ? C ASN 53  ND2 
261 1 Y 1 C GLN 44  ? CG  ? C GLN 62  CG  
262 1 Y 1 C GLN 44  ? CD  ? C GLN 62  CD  
263 1 Y 1 C GLN 44  ? OE1 ? C GLN 62  OE1 
264 1 Y 1 C GLN 44  ? NE2 ? C GLN 62  NE2 
265 1 Y 1 C ARG 46  ? CG  ? C ARG 64  CG  
266 1 Y 1 C ARG 46  ? CD  ? C ARG 64  CD  
267 1 Y 1 C ARG 46  ? NE  ? C ARG 64  NE  
268 1 Y 1 C ARG 46  ? CZ  ? C ARG 64  CZ  
269 1 Y 1 C ARG 46  ? NH1 ? C ARG 64  NH1 
270 1 Y 1 C ARG 46  ? NH2 ? C ARG 64  NH2 
271 1 Y 1 C ARG 197 ? CG  ? C ARG 215 CG  
272 1 Y 1 C ARG 197 ? CD  ? C ARG 215 CD  
273 1 Y 1 C ARG 197 ? NE  ? C ARG 215 NE  
274 1 Y 1 C ARG 197 ? CZ  ? C ARG 215 CZ  
275 1 Y 1 C ARG 197 ? NH1 ? C ARG 215 NH1 
276 1 Y 1 C ARG 197 ? NH2 ? C ARG 215 NH2 
277 1 Y 1 C ASP 291 ? CG  ? C ASP 309 CG  
278 1 Y 1 C ASP 291 ? OD1 ? C ASP 309 OD1 
279 1 Y 1 C ASP 291 ? OD2 ? C ASP 309 OD2 
280 1 Y 1 D ARG 13  ? CG  ? D ARG 13  CG  
281 1 Y 1 D ARG 13  ? CD  ? D ARG 13  CD  
282 1 Y 1 D ARG 13  ? NE  ? D ARG 13  NE  
283 1 Y 1 D ARG 13  ? CZ  ? D ARG 13  CZ  
284 1 Y 1 D ARG 13  ? NH1 ? D ARG 13  NH1 
285 1 Y 1 D ARG 13  ? NH2 ? D ARG 13  NH2 
286 1 Y 1 D GLU 17  ? CG  ? D GLU 17  CG  
287 1 Y 1 D GLU 17  ? CD  ? D GLU 17  CD  
288 1 Y 1 D GLU 17  ? OE1 ? D GLU 17  OE1 
289 1 Y 1 D GLU 17  ? OE2 ? D GLU 17  OE2 
290 1 Y 1 D MET 21  ? CG  ? D MET 21  CG  
291 1 Y 1 D MET 21  ? SD  ? D MET 21  SD  
292 1 Y 1 D MET 21  ? CE  ? D MET 21  CE  
293 1 Y 1 D ASP 26  ? CG  ? D ASP 26  CG  
294 1 Y 1 D ASP 26  ? OD1 ? D ASP 26  OD1 
295 1 Y 1 D ASP 26  ? OD2 ? D ASP 26  OD2 
296 1 Y 1 D LYS 29  ? CG  ? D LYS 29  CG  
297 1 Y 1 D LYS 29  ? CD  ? D LYS 29  CD  
298 1 Y 1 D LYS 29  ? CE  ? D LYS 29  CE  
299 1 Y 1 D LYS 29  ? NZ  ? D LYS 29  NZ  
300 1 Y 1 D LYS 32  ? CG  ? D LYS 32  CG  
301 1 Y 1 D LYS 32  ? CD  ? D LYS 32  CD  
302 1 Y 1 D LYS 32  ? CE  ? D LYS 32  CE  
303 1 Y 1 D LYS 32  ? NZ  ? D LYS 32  NZ  
304 1 Y 1 D ASP 36  ? CG  ? D ASP 36  CG  
305 1 Y 1 D ASP 36  ? OD1 ? D ASP 36  OD1 
306 1 Y 1 D ASP 36  ? OD2 ? D ASP 36  OD2 
307 1 Y 1 D LYS 46  ? CG  ? D LYS 46  CG  
308 1 Y 1 D LYS 46  ? CD  ? D LYS 46  CD  
309 1 Y 1 D LYS 46  ? CE  ? D LYS 46  CE  
310 1 Y 1 D LYS 46  ? NZ  ? D LYS 46  NZ  
311 1 Y 1 E GLU 46  ? CG  ? E GLU 46  CG  
312 1 Y 1 E GLU 46  ? CD  ? E GLU 46  CD  
313 1 Y 1 E GLU 46  ? OE1 ? E GLU 46  OE1 
314 1 Y 1 E GLU 46  ? OE2 ? E GLU 46  OE2 
315 1 Y 1 E LYS 76  ? CG  ? E LYS 76  CG  
316 1 Y 1 E LYS 76  ? CD  ? E LYS 76  CD  
317 1 Y 1 E LYS 76  ? CE  ? E LYS 76  CE  
318 1 Y 1 E LYS 76  ? NZ  ? E LYS 76  NZ  
319 1 Y 1 E GLU 89  ? CG  ? E GLU 89  CG  
320 1 Y 1 E GLU 89  ? CD  ? E GLU 89  CD  
321 1 Y 1 E GLU 89  ? OE1 ? E GLU 89  OE1 
322 1 Y 1 E GLU 89  ? OE2 ? E GLU 89  OE2 
323 1 Y 1 E GLN 130 ? CG  ? E GLN 142 CG  
324 1 Y 1 E GLN 130 ? CD  ? E GLN 142 CD  
325 1 Y 1 E GLN 130 ? OE1 ? E GLN 142 OE1 
326 1 Y 1 E GLN 130 ? NE2 ? E GLN 142 NE2 
327 1 Y 1 E THR 132 ? OG1 ? E THR 144 OG1 
328 1 Y 1 E THR 132 ? CG2 ? E THR 144 CG2 
329 1 Y 1 E GLU 141 ? CG  ? E GLU 153 CG  
330 1 Y 1 E GLU 141 ? CD  ? E GLU 153 CD  
331 1 Y 1 E GLU 141 ? OE1 ? E GLU 153 OE1 
332 1 Y 1 E GLU 141 ? OE2 ? E GLU 153 OE2 
333 1 Y 1 E ARG 206 ? CG  ? E ARG 218 CG  
334 1 Y 1 E ARG 206 ? CD  ? E ARG 218 CD  
335 1 Y 1 E ARG 206 ? NE  ? E ARG 218 NE  
336 1 Y 1 E ARG 206 ? CZ  ? E ARG 218 CZ  
337 1 Y 1 E ARG 206 ? NH1 ? E ARG 218 NH1 
338 1 Y 1 E ARG 206 ? NH2 ? E ARG 218 NH2 
339 1 Y 1 E GLU 210 ? CG  ? E GLU 222 CG  
340 1 Y 1 E GLU 210 ? CD  ? E GLU 222 CD  
341 1 Y 1 E GLU 210 ? OE1 ? E GLU 222 OE1 
342 1 Y 1 E GLU 210 ? OE2 ? E GLU 222 OE2 
343 1 Y 1 E GLU 234 ? CG  ? E GLU 246 CG  
344 1 Y 1 E GLU 234 ? CD  ? E GLU 246 CD  
345 1 Y 1 E GLU 234 ? OE1 ? E GLU 246 OE1 
346 1 Y 1 E GLU 234 ? OE2 ? E GLU 246 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9ARY 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9ARY 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9ARY 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9ARY 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.27 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'REAL-SPACE (WEIGHTED MAP SUM AT ATOM CENTERS)' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005 ? 1901 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.751 ? 2612 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 6.111 ? 265  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.048 ? 332  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.009 ? 315  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9ARY 
_struct.title                        
;Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9ARY 
_struct_keywords.text            'GPCR, G-protein Coupled Receptor, 5-HT2AR, serotonin, psychedelics, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP 5HT2A_HUMAN P28223 ? 1 
;MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSENRTNLSCEGCLSPSCLSLLHLQEKNWSALL
TAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADMLLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFST
ASIMHLCAISLDRYVAIQNPIHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLFQRSIHREPGSYTGRRTMQSISNEQK
ACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNEDVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYK
ENKKPLQLILVNTIPALAYKSSQLQMGQKKNSKQDAKTTDNDCSMVALGKQHSEEASKDNSDGVNEKVSCV
;
1 
2 PDB 9ARY        9ARY   ? 2 ? 1 
3 UNP GBB1_HUMAN  P62873 ? 3 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
4 UNP GBG2_HUMAN  P59768 ? 4 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
5 PDB 9ARY        9ARY   ? 5 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9ARY A 1  ? 471 ? P28223 1 ? 471 ? 1 471 
2 2 9ARY B 1  ? 246 ? 9ARY   1 ? 246 ? 1 246 
3 3 9ARY C 20 ? 358 ? P62873 2 ? 340 ? 2 340 
4 4 9ARY D 1  ? 71  ? P59768 1 ? 71  ? 1 71  
5 5 9ARY E 1  ? 267 ? 9ARY   1 ? 255 ? 1 255 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 9ARY MET C 1  ? UNP P62873 ? ? 'expression tag' -17 1  
3 9ARY HIS C 2  ? UNP P62873 ? ? 'expression tag' -16 2  
3 9ARY HIS C 3  ? UNP P62873 ? ? 'expression tag' -15 3  
3 9ARY HIS C 4  ? UNP P62873 ? ? 'expression tag' -14 4  
3 9ARY HIS C 5  ? UNP P62873 ? ? 'expression tag' -13 5  
3 9ARY HIS C 6  ? UNP P62873 ? ? 'expression tag' -12 6  
3 9ARY HIS C 7  ? UNP P62873 ? ? 'expression tag' -11 7  
3 9ARY LEU C 8  ? UNP P62873 ? ? 'expression tag' -10 8  
3 9ARY GLU C 9  ? UNP P62873 ? ? 'expression tag' -9  9  
3 9ARY VAL C 10 ? UNP P62873 ? ? 'expression tag' -8  10 
3 9ARY LEU C 11 ? UNP P62873 ? ? 'expression tag' -7  11 
3 9ARY PHE C 12 ? UNP P62873 ? ? 'expression tag' -6  12 
3 9ARY GLN C 13 ? UNP P62873 ? ? 'expression tag' -5  13 
3 9ARY GLY C 14 ? UNP P62873 ? ? 'expression tag' -4  14 
3 9ARY PRO C 15 ? UNP P62873 ? ? 'expression tag' -3  15 
3 9ARY GLY C 16 ? UNP P62873 ? ? 'expression tag' -2  16 
3 9ARY SER C 17 ? UNP P62873 ? ? 'expression tag' -1  17 
3 9ARY SER C 18 ? UNP P62873 ? ? 'expression tag' 0   18 
3 9ARY GLY C 19 ? UNP P62873 ? ? 'expression tag' 1   19 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 80  ? GLU A 102 ? LEU A 80  GLU A 102 1 ? 23 
HELX_P HELX_P2  AA2 LYS A 103 ? GLN A 106 ? LYS A 103 GLN A 106 5 ? 4  
HELX_P HELX_P3  AA3 ASN A 107 ? VAL A 127 ? ASN A 107 VAL A 127 1 ? 21 
HELX_P HELX_P4  AA4 VAL A 127 ? TYR A 137 ? VAL A 127 TYR A 137 1 ? 11 
HELX_P HELX_P5  AA5 PRO A 144 ? LYS A 146 ? PRO A 144 LYS A 146 5 ? 3  
HELX_P HELX_P6  AA6 LEU A 147 ? ASN A 179 ? LEU A 147 ASN A 179 1 ? 33 
HELX_P HELX_P7  AA7 ASN A 179 ? PHE A 186 ? ASN A 179 PHE A 186 1 ? 8  
HELX_P HELX_P8  AA8 SER A 188 ? SER A 207 ? SER A 188 SER A 207 1 ? 20 
HELX_P HELX_P9  AA9 MET A 208 ? PHE A 213 ? MET A 208 PHE A 213 1 ? 6  
HELX_P HELX_P10 AB1 ASP A 217 ? VAL A 221 ? ASP A 217 VAL A 221 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 231 ? PHE A 243 ? ASP A 231 PHE A 243 1 ? 13 
HELX_P HELX_P12 AB3 PHE A 243 ? LEU A 261 ? PHE A 243 LEU A 261 1 ? 19 
HELX_P HELX_P13 AB4 SER A 314 ? CYS A 349 ? SER A 314 CYS A 349 1 ? 36 
HELX_P HELX_P14 AB5 VAL A 357 ? LEU A 382 ? VAL A 357 LEU A 382 1 ? 26 
HELX_P HELX_P15 AB6 ASN A 384 ? ALA A 390 ? ASN A 384 ALA A 390 1 ? 7  
HELX_P HELX_P16 AB7 SER B 6   ? ARG B 31  ? SER B 6   ARG B 31  1 ? 26 
HELX_P HELX_P17 AB8 GLY B 45  ? VAL B 50  ? GLY B 45  VAL B 50  5 ? 6  
HELX_P HELX_P18 AB9 ARG B 117 ? ASN B 130 ? ARG B 117 ASN B 130 1 ? 14 
HELX_P HELX_P19 AC1 LYS B 145 ? GLY B 156 ? LYS B 145 GLY B 156 1 ? 12 
HELX_P HELX_P20 AC2 LYS B 159 ? PHE B 164 ? LYS B 159 PHE B 164 1 ? 6  
HELX_P HELX_P21 AC3 PRO B 165 ? ALA B 168 ? PRO B 165 ALA B 168 5 ? 4  
HELX_P HELX_P22 AC4 ASP B 183 ? SER B 204 ? ASP B 183 SER B 204 1 ? 22 
HELX_P HELX_P23 AC5 ASN B 223 ? TYR B 243 ? ASN B 223 TYR B 243 1 ? 21 
HELX_P HELX_P24 AC6 LEU C 22  ? CYS C 43  ? LEU C 4   CYS C 25  1 ? 22 
HELX_P HELX_P25 AC7 THR C 47  ? THR C 52  ? THR C 29  THR C 34  1 ? 6  
HELX_P HELX_P26 AC8 THR C 146 ? ASN C 150 ? THR C 128 ASN C 132 5 ? 5  
HELX_P HELX_P27 AC9 ALA D 10  ? ASN D 24  ? ALA D 10  ASN D 24  1 ? 15 
HELX_P HELX_P28 AD1 LYS D 29  ? HIS D 44  ? LYS D 29  HIS D 44  1 ? 16 
HELX_P HELX_P29 AD2 ALA D 45  ? ASP D 48  ? ALA D 45  ASP D 48  5 ? 4  
HELX_P HELX_P30 AD3 ALA E 28  ? PHE E 32  ? ALA E 28  PHE E 32  5 ? 5  
HELX_P HELX_P31 AD4 SER E 53  ? GLY E 56  ? SER E 53  GLY E 56  5 ? 4  
HELX_P HELX_P32 AD5 ASP E 62  ? LYS E 65  ? ASP E 62  LYS E 65  5 ? 4  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 148 SG ? ? ? 1_555 A CYS 227 SG ? ? A CYS 148 A CYS 227 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ? ? E CYS 22  SG ? ? ? 1_555 E CYS 96  SG ? ? E CYS 22  E CYS 96  1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf3 disulf ? ? E CYS 159 SG ? ? ? 1_555 E CYS 229 SG ? ? E CYS 147 E CYS 217 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 148 ? CYS A 227 ? CYS A 148 ? 1_555 CYS A 227 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS E 22  ? CYS E 96  ? CYS E 22  ? 1_555 CYS E 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 159 ? CYS E 229 ? CYS E 147 ? 1_555 CYS E 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          E 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           E 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   E 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    E 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -0.62 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 5 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 6 ? 
AB6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB5 4 5 ? anti-parallel 
AB5 5 6 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 PHE B 70  ? VAL B 76  ? PHE B 70  VAL B 76  
AA1 2 VAL B 79  ? ASP B 85  ? VAL B 79  ASP B 85  
AA1 3 LEU B 34  ? GLY B 40  ? LEU B 34  GLY B 40  
AA1 4 ALA B 105 ? ASP B 111 ? ALA B 105 ASP B 111 
AA1 5 SER B 138 ? ASN B 144 ? SER B 138 ASN B 144 
AA1 6 CYS B 211 ? PHE B 215 ? CYS B 211 PHE B 215 
AA2 1 THR C 65  ? LEU C 69  ? THR C 47  LEU C 51  
AA2 2 LEU C 354 ? TRP C 357 ? LEU C 336 TRP C 339 
AA2 3 VAL C 345 ? SER C 349 ? VAL C 327 SER C 331 
AA2 4 VAL C 333 ? VAL C 338 ? VAL C 315 VAL C 320 
AA3 1 ILE C 76  ? TRP C 81  ? ILE C 58  TRP C 63  
AA3 2 LEU C 87  ? SER C 92  ? LEU C 69  SER C 74  
AA3 3 LYS C 96  ? ASP C 101 ? LYS C 78  ASP C 83  
AA3 4 ASN C 106 ? PRO C 112 ? ASN C 88  PRO C 94  
AA4 1 VAL C 118 ? TYR C 123 ? VAL C 100 TYR C 105 
AA4 2 TYR C 129 ? GLY C 134 ? TYR C 111 GLY C 116 
AA4 3 ILE C 138 ? ASN C 143 ? ILE C 120 ASN C 125 
AA4 4 ARG C 152 ? ALA C 158 ? ARG C 134 ALA C 140 
AA5 1 LEU C 164 ? PHE C 169 ? LEU C 146 PHE C 151 
AA5 2 GLN C 174 ? SER C 179 ? GLN C 156 SER C 161 
AA5 3 CYS C 184 ? ASP C 188 ? CYS C 166 ASP C 170 
AA5 4 GLN C 193 ? PHE C 198 ? GLN C 175 PHE C 180 
AA6 1 VAL C 205 ? SER C 209 ? VAL C 187 SER C 191 
AA6 2 VAL C 218 ? ALA C 221 ? VAL C 200 ALA C 203 
AA6 3 ALA C 226 ? LEU C 228 ? ALA C 208 LEU C 210 
AA6 4 GLN C 238 ? PHE C 240 ? GLN C 220 PHE C 222 
AA7 1 ILE C 247 ? ILE C 250 ? ILE C 229 ILE C 232 
AA7 2 ALA C 258 ? SER C 263 ? ALA C 240 SER C 245 
AA7 3 CYS C 268 ? ASP C 272 ? CYS C 250 ASP C 254 
AA7 4 GLU C 278 ? TYR C 282 ? GLU C 260 TYR C 264 
AA8 1 ILE C 291 ? PHE C 296 ? ILE C 273 PHE C 278 
AA8 2 LEU C 302 ? TYR C 307 ? LEU C 284 TYR C 289 
AA8 3 CYS C 312 ? ASP C 316 ? CYS C 294 ASP C 298 
AA8 4 ARG C 322 ? LEU C 326 ? ARG C 304 LEU C 308 
AA9 1 GLN E 3   ? SER E 7   ? GLN E 3   SER E 7   
AA9 2 SER E 17  ? SER E 25  ? SER E 17  SER E 25  
AA9 3 THR E 78  ? THR E 84  ? THR E 78  THR E 84  
AA9 4 PHE E 68  ? THR E 69  ? PHE E 68  THR E 69  
AB1 1 GLN E 3   ? SER E 7   ? GLN E 3   SER E 7   
AB1 2 SER E 17  ? SER E 25  ? SER E 17  SER E 25  
AB1 3 THR E 78  ? THR E 84  ? THR E 78  THR E 84  
AB1 4 ARG E 72  ? ASP E 73  ? ARG E 72  ASP E 73  
AB2 1 GLY E 10  ? LEU E 11  ? GLY E 10  LEU E 11  
AB2 2 THR E 115 ? THR E 118 ? THR E 115 THR E 118 
AB2 3 ALA E 92  ? TYR E 94  ? ALA E 92  TYR E 94  
AB2 4 ARG E 38  ? GLN E 39  ? ARG E 38  GLN E 39  
AB2 5 LEU E 45  ? GLU E 46  ? LEU E 45  GLU E 46  
AB3 1 GLY E 33  ? MET E 34  ? GLY E 33  MET E 34  
AB3 2 ARG E 98  ? SER E 99  ? ARG E 98  SER E 99  
AB4 1 ALA E 49  ? ILE E 51  ? ALA E 49  ILE E 51  
AB4 2 ILE E 58  ? TYR E 60  ? ILE E 58  TYR E 60  
AB5 1 SER E 146 ? PRO E 148 ? SER E 134 PRO E 136 
AB5 2 THR E 243 ? GLU E 246 ? THR E 231 GLU E 234 
AB5 3 VAL E 226 ? GLN E 231 ? VAL E 214 GLN E 219 
AB5 4 LEU E 174 ? GLN E 179 ? LEU E 162 GLN E 167 
AB5 5 GLN E 186 ? TYR E 190 ? GLN E 174 TYR E 178 
AB5 6 ASN E 194 ? LEU E 195 ? ASN E 182 LEU E 183 
AB6 1 VAL E 155 ? ARG E 160 ? VAL E 143 ARG E 148 
AB6 2 ALA E 211 ? ILE E 216 ? ALA E 199 ILE E 204 
AB6 3 PHE E 203 ? SER E 208 ? PHE E 191 SER E 196 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR B 72  ? N THR B 72  O MET B 83  ? O MET B 83  
AA1 2 3 O HIS B 82  ? O HIS B 82  N LEU B 36  ? N LEU B 36  
AA1 3 4 N LEU B 37  ? N LEU B 37  O ILE B 107 ? O ILE B 107 
AA1 4 5 N ILE B 106 ? N ILE B 106 O ILE B 140 ? O ILE B 140 
AA1 5 6 N LEU B 143 ? N LEU B 143 O HIS B 214 ? O HIS B 214 
AA2 1 2 N ARG C 67  ? N ARG C 49  O ILE C 356 ? O ILE C 338 
AA2 2 3 O TRP C 357 ? O TRP C 339 N VAL C 345 ? N VAL C 327 
AA2 3 4 O ALA C 346 ? O ALA C 328 N GLY C 337 ? N GLY C 319 
AA3 1 2 N ALA C 78  ? N ALA C 60  O ALA C 91  ? O ALA C 73  
AA3 2 3 N LEU C 88  ? N LEU C 70  O TRP C 100 ? O TRP C 82  
AA3 3 4 N ILE C 99  ? N ILE C 81  O VAL C 108 ? O VAL C 90  
AA4 1 2 N MET C 119 ? N MET C 101 O GLY C 133 ? O GLY C 115 
AA4 2 3 N VAL C 130 ? N VAL C 112 O TYR C 142 ? O TYR C 124 
AA4 3 4 N CYS C 139 ? N CYS C 121 O LEU C 157 ? O LEU C 139 
AA5 1 2 N ARG C 168 ? N ARG C 150 O VAL C 176 ? O VAL C 158 
AA5 2 3 N ILE C 175 ? N ILE C 157 O TRP C 187 ? O TRP C 169 
AA5 3 4 N CYS C 184 ? N CYS C 166 O PHE C 198 ? O PHE C 180 
AA6 1 2 N MET C 206 ? N MET C 188 O GLY C 220 ? O GLY C 202 
AA6 2 3 N SER C 219 ? N SER C 201 O LYS C 227 ? O LYS C 209 
AA6 3 4 N LEU C 228 ? N LEU C 210 O GLN C 238 ? O GLN C 220 
AA7 1 2 N ASN C 248 ? N ASN C 230 O GLY C 262 ? O GLY C 244 
AA7 2 3 N PHE C 259 ? N PHE C 241 O PHE C 271 ? O PHE C 253 
AA7 3 4 N CYS C 268 ? N CYS C 250 O TYR C 282 ? O TYR C 264 
AA8 1 2 N THR C 292 ? N THR C 274 O GLY C 306 ? O GLY C 288 
AA8 2 3 N LEU C 303 ? N LEU C 285 O TRP C 315 ? O TRP C 297 
AA8 3 4 N VAL C 314 ? N VAL C 296 O ALA C 323 ? O ALA C 305 
AA9 1 2 N VAL E 5   ? N VAL E 5   O SER E 23  ? O SER E 23  
AA9 2 3 N CYS E 22  ? N CYS E 22  O LEU E 79  ? O LEU E 79  
AA9 3 4 O GLN E 82  ? O GLN E 82  N THR E 69  ? N THR E 69  
AB1 1 2 N VAL E 5   ? N VAL E 5   O SER E 23  ? O SER E 23  
AB1 2 3 N CYS E 22  ? N CYS E 22  O LEU E 79  ? O LEU E 79  
AB1 3 4 O THR E 78  ? O THR E 78  N ASP E 73  ? N ASP E 73  
AB2 1 2 N GLY E 10  ? N GLY E 10  O THR E 116 ? O THR E 116 
AB2 2 3 O LEU E 117 ? O LEU E 117 N ALA E 92  ? N ALA E 92  
AB2 3 4 O MET E 93  ? O MET E 93  N GLN E 39  ? N GLN E 39  
AB2 4 5 N ARG E 38  ? N ARG E 38  O GLU E 46  ? O GLU E 46  
AB3 1 2 N GLY E 33  ? N GLY E 33  O SER E 99  ? O SER E 99  
AB4 1 2 N TYR E 50  ? N TYR E 50  O TYR E 59  ? O TYR E 59  
AB5 1 2 N VAL E 147 ? N VAL E 135 O LYS E 244 ? O LYS E 232 
AB5 2 3 O THR E 243 ? O THR E 231 N TYR E 227 ? N TYR E 215 
AB5 3 4 O TYR E 228 ? O TYR E 216 N PHE E 177 ? N PHE E 165 
AB5 4 5 N TRP E 176 ? N TRP E 164 O LEU E 188 ? O LEU E 176 
AB5 5 6 N TYR E 190 ? N TYR E 178 O ASN E 194 ? O ASN E 182 
AB6 1 2 N ILE E 157 ? N ILE E 145 O LEU E 214 ? O LEU E 202 
AB6 2 3 O THR E 215 ? O THR E 203 N SER E 204 ? N SER E 192 
# 
_pdbx_entry_details.entry_id                   9ARY 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 261 ? ? -99.70  35.28   
2 1 LEU C 190 ? ? -170.96 148.76  
3 1 CYS C 233 ? ? -126.78 -167.20 
4 1 ALA E 92  ? ? -170.41 -173.96 
5 1 MET E 180 ? ? 73.40   -12.95  
6 1 SER E 181 ? ? -132.62 -36.85  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9ARY 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9ARY 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.27 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               157415 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 '5-HT2AR in complex with mini-Gq' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        9ARY 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            OTHER 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             160 
_em_imaging.nominal_defocus_max             2600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9ARY 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9ARY 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A ASP 2   ? A ASP 2   
3   1 Y 1 A ILE 3   ? A ILE 3   
4   1 Y 1 A LEU 4   ? A LEU 4   
5   1 Y 1 A CYS 5   ? A CYS 5   
6   1 Y 1 A GLU 6   ? A GLU 6   
7   1 Y 1 A GLU 7   ? A GLU 7   
8   1 Y 1 A ASN 8   ? A ASN 8   
9   1 Y 1 A THR 9   ? A THR 9   
10  1 Y 1 A SER 10  ? A SER 10  
11  1 Y 1 A LEU 11  ? A LEU 11  
12  1 Y 1 A SER 12  ? A SER 12  
13  1 Y 1 A SER 13  ? A SER 13  
14  1 Y 1 A THR 14  ? A THR 14  
15  1 Y 1 A THR 15  ? A THR 15  
16  1 Y 1 A ASN 16  ? A ASN 16  
17  1 Y 1 A SER 17  ? A SER 17  
18  1 Y 1 A LEU 18  ? A LEU 18  
19  1 Y 1 A MET 19  ? A MET 19  
20  1 Y 1 A GLN 20  ? A GLN 20  
21  1 Y 1 A LEU 21  ? A LEU 21  
22  1 Y 1 A ASN 22  ? A ASN 22  
23  1 Y 1 A ASP 23  ? A ASP 23  
24  1 Y 1 A ASP 24  ? A ASP 24  
25  1 Y 1 A THR 25  ? A THR 25  
26  1 Y 1 A ARG 26  ? A ARG 26  
27  1 Y 1 A LEU 27  ? A LEU 27  
28  1 Y 1 A TYR 28  ? A TYR 28  
29  1 Y 1 A SER 29  ? A SER 29  
30  1 Y 1 A ASN 30  ? A ASN 30  
31  1 Y 1 A ASP 31  ? A ASP 31  
32  1 Y 1 A PHE 32  ? A PHE 32  
33  1 Y 1 A ASN 33  ? A ASN 33  
34  1 Y 1 A SER 34  ? A SER 34  
35  1 Y 1 A GLY 35  ? A GLY 35  
36  1 Y 1 A GLU 36  ? A GLU 36  
37  1 Y 1 A ALA 37  ? A ALA 37  
38  1 Y 1 A ASN 38  ? A ASN 38  
39  1 Y 1 A THR 39  ? A THR 39  
40  1 Y 1 A SER 40  ? A SER 40  
41  1 Y 1 A ASP 41  ? A ASP 41  
42  1 Y 1 A ALA 42  ? A ALA 42  
43  1 Y 1 A PHE 43  ? A PHE 43  
44  1 Y 1 A ASN 44  ? A ASN 44  
45  1 Y 1 A TRP 45  ? A TRP 45  
46  1 Y 1 A THR 46  ? A THR 46  
47  1 Y 1 A VAL 47  ? A VAL 47  
48  1 Y 1 A ASP 48  ? A ASP 48  
49  1 Y 1 A SER 49  ? A SER 49  
50  1 Y 1 A GLU 50  ? A GLU 50  
51  1 Y 1 A ASN 51  ? A ASN 51  
52  1 Y 1 A ARG 52  ? A ARG 52  
53  1 Y 1 A THR 53  ? A THR 53  
54  1 Y 1 A ASN 54  ? A ASN 54  
55  1 Y 1 A LEU 55  ? A LEU 55  
56  1 Y 1 A SER 56  ? A SER 56  
57  1 Y 1 A CYS 57  ? A CYS 57  
58  1 Y 1 A GLU 58  ? A GLU 58  
59  1 Y 1 A GLY 59  ? A GLY 59  
60  1 Y 1 A CYS 60  ? A CYS 60  
61  1 Y 1 A LEU 61  ? A LEU 61  
62  1 Y 1 A SER 62  ? A SER 62  
63  1 Y 1 A PRO 63  ? A PRO 63  
64  1 Y 1 A SER 64  ? A SER 64  
65  1 Y 1 A CYS 65  ? A CYS 65  
66  1 Y 1 A LEU 66  ? A LEU 66  
67  1 Y 1 A SER 67  ? A SER 67  
68  1 Y 1 A LEU 68  ? A LEU 68  
69  1 Y 1 A LEU 69  ? A LEU 69  
70  1 Y 1 A HIS 70  ? A HIS 70  
71  1 Y 1 A LEU 71  ? A LEU 71  
72  1 Y 1 A GLN 72  ? A GLN 72  
73  1 Y 1 A GLU 73  ? A GLU 73  
74  1 Y 1 A LYS 74  ? A LYS 74  
75  1 Y 1 A ASN 75  ? A ASN 75  
76  1 Y 1 A TRP 76  ? A TRP 76  
77  1 Y 1 A SER 77  ? A SER 77  
78  1 Y 1 A ALA 78  ? A ALA 78  
79  1 Y 1 A LYS 263 ? A LYS 263 
80  1 Y 1 A GLU 264 ? A GLU 264 
81  1 Y 1 A ALA 265 ? A ALA 265 
82  1 Y 1 A THR 266 ? A THR 266 
83  1 Y 1 A LEU 267 ? A LEU 267 
84  1 Y 1 A CYS 268 ? A CYS 268 
85  1 Y 1 A VAL 269 ? A VAL 269 
86  1 Y 1 A SER 270 ? A SER 270 
87  1 Y 1 A ASP 271 ? A ASP 271 
88  1 Y 1 A LEU 272 ? A LEU 272 
89  1 Y 1 A GLY 273 ? A GLY 273 
90  1 Y 1 A THR 274 ? A THR 274 
91  1 Y 1 A ARG 275 ? A ARG 275 
92  1 Y 1 A ALA 276 ? A ALA 276 
93  1 Y 1 A LYS 277 ? A LYS 277 
94  1 Y 1 A LEU 278 ? A LEU 278 
95  1 Y 1 A ALA 279 ? A ALA 279 
96  1 Y 1 A SER 280 ? A SER 280 
97  1 Y 1 A PHE 281 ? A PHE 281 
98  1 Y 1 A SER 282 ? A SER 282 
99  1 Y 1 A PHE 283 ? A PHE 283 
100 1 Y 1 A LEU 284 ? A LEU 284 
101 1 Y 1 A PRO 285 ? A PRO 285 
102 1 Y 1 A GLN 286 ? A GLN 286 
103 1 Y 1 A SER 287 ? A SER 287 
104 1 Y 1 A SER 288 ? A SER 288 
105 1 Y 1 A LEU 289 ? A LEU 289 
106 1 Y 1 A SER 290 ? A SER 290 
107 1 Y 1 A SER 291 ? A SER 291 
108 1 Y 1 A GLU 292 ? A GLU 292 
109 1 Y 1 A LYS 293 ? A LYS 293 
110 1 Y 1 A LEU 294 ? A LEU 294 
111 1 Y 1 A PHE 295 ? A PHE 295 
112 1 Y 1 A GLN 296 ? A GLN 296 
113 1 Y 1 A ARG 297 ? A ARG 297 
114 1 Y 1 A SER 298 ? A SER 298 
115 1 Y 1 A ILE 299 ? A ILE 299 
116 1 Y 1 A HIS 300 ? A HIS 300 
117 1 Y 1 A ARG 301 ? A ARG 301 
118 1 Y 1 A GLU 302 ? A GLU 302 
119 1 Y 1 A PRO 303 ? A PRO 303 
120 1 Y 1 A GLY 304 ? A GLY 304 
121 1 Y 1 A SER 305 ? A SER 305 
122 1 Y 1 A TYR 306 ? A TYR 306 
123 1 Y 1 A THR 307 ? A THR 307 
124 1 Y 1 A GLY 308 ? A GLY 308 
125 1 Y 1 A ARG 309 ? A ARG 309 
126 1 Y 1 A ARG 310 ? A ARG 310 
127 1 Y 1 A THR 311 ? A THR 311 
128 1 Y 1 A MET 312 ? A MET 312 
129 1 Y 1 A LYS 350 ? A LYS 350 
130 1 Y 1 A GLU 351 ? A GLU 351 
131 1 Y 1 A SER 352 ? A SER 352 
132 1 Y 1 A CYS 353 ? A CYS 353 
133 1 Y 1 A ASN 354 ? A ASN 354 
134 1 Y 1 A GLU 355 ? A GLU 355 
135 1 Y 1 A PHE 391 ? A PHE 391 
136 1 Y 1 A SER 392 ? A SER 392 
137 1 Y 1 A ARG 393 ? A ARG 393 
138 1 Y 1 A TYR 394 ? A TYR 394 
139 1 Y 1 A ILE 395 ? A ILE 395 
140 1 Y 1 A GLN 396 ? A GLN 396 
141 1 Y 1 A CYS 397 ? A CYS 397 
142 1 Y 1 A GLN 398 ? A GLN 398 
143 1 Y 1 A TYR 399 ? A TYR 399 
144 1 Y 1 A LYS 400 ? A LYS 400 
145 1 Y 1 A GLU 401 ? A GLU 401 
146 1 Y 1 A ASN 402 ? A ASN 402 
147 1 Y 1 A LYS 403 ? A LYS 403 
148 1 Y 1 A LYS 404 ? A LYS 404 
149 1 Y 1 A PRO 405 ? A PRO 405 
150 1 Y 1 A LEU 406 ? A LEU 406 
151 1 Y 1 A GLN 407 ? A GLN 407 
152 1 Y 1 A LEU 408 ? A LEU 408 
153 1 Y 1 A ILE 409 ? A ILE 409 
154 1 Y 1 A LEU 410 ? A LEU 410 
155 1 Y 1 A VAL 411 ? A VAL 411 
156 1 Y 1 A ASN 412 ? A ASN 412 
157 1 Y 1 A THR 413 ? A THR 413 
158 1 Y 1 A ILE 414 ? A ILE 414 
159 1 Y 1 A PRO 415 ? A PRO 415 
160 1 Y 1 A ALA 416 ? A ALA 416 
161 1 Y 1 A LEU 417 ? A LEU 417 
162 1 Y 1 A ALA 418 ? A ALA 418 
163 1 Y 1 A TYR 419 ? A TYR 419 
164 1 Y 1 A LYS 420 ? A LYS 420 
165 1 Y 1 A SER 421 ? A SER 421 
166 1 Y 1 A SER 422 ? A SER 422 
167 1 Y 1 A GLN 423 ? A GLN 423 
168 1 Y 1 A LEU 424 ? A LEU 424 
169 1 Y 1 A GLN 425 ? A GLN 425 
170 1 Y 1 A MET 426 ? A MET 426 
171 1 Y 1 A GLY 427 ? A GLY 427 
172 1 Y 1 A GLN 428 ? A GLN 428 
173 1 Y 1 A LYS 429 ? A LYS 429 
174 1 Y 1 A LYS 430 ? A LYS 430 
175 1 Y 1 A ASN 431 ? A ASN 431 
176 1 Y 1 A SER 432 ? A SER 432 
177 1 Y 1 A LYS 433 ? A LYS 433 
178 1 Y 1 A GLN 434 ? A GLN 434 
179 1 Y 1 A ASP 435 ? A ASP 435 
180 1 Y 1 A ALA 436 ? A ALA 436 
181 1 Y 1 A LYS 437 ? A LYS 437 
182 1 Y 1 A THR 438 ? A THR 438 
183 1 Y 1 A THR 439 ? A THR 439 
184 1 Y 1 A ASP 440 ? A ASP 440 
185 1 Y 1 A ASN 441 ? A ASN 441 
186 1 Y 1 A ASP 442 ? A ASP 442 
187 1 Y 1 A CYS 443 ? A CYS 443 
188 1 Y 1 A SER 444 ? A SER 444 
189 1 Y 1 A MET 445 ? A MET 445 
190 1 Y 1 A VAL 446 ? A VAL 446 
191 1 Y 1 A ALA 447 ? A ALA 447 
192 1 Y 1 A LEU 448 ? A LEU 448 
193 1 Y 1 A GLY 449 ? A GLY 449 
194 1 Y 1 A LYS 450 ? A LYS 450 
195 1 Y 1 A GLN 451 ? A GLN 451 
196 1 Y 1 A HIS 452 ? A HIS 452 
197 1 Y 1 A SER 453 ? A SER 453 
198 1 Y 1 A GLU 454 ? A GLU 454 
199 1 Y 1 A GLU 455 ? A GLU 455 
200 1 Y 1 A ALA 456 ? A ALA 456 
201 1 Y 1 A SER 457 ? A SER 457 
202 1 Y 1 A LYS 458 ? A LYS 458 
203 1 Y 1 A ASP 459 ? A ASP 459 
204 1 Y 1 A ASN 460 ? A ASN 460 
205 1 Y 1 A SER 461 ? A SER 461 
206 1 Y 1 A ASP 462 ? A ASP 462 
207 1 Y 1 A GLY 463 ? A GLY 463 
208 1 Y 1 A VAL 464 ? A VAL 464 
209 1 Y 1 A ASN 465 ? A ASN 465 
210 1 Y 1 A GLU 466 ? A GLU 466 
211 1 Y 1 A LYS 467 ? A LYS 467 
212 1 Y 1 A VAL 468 ? A VAL 468 
213 1 Y 1 A SER 469 ? A SER 469 
214 1 Y 1 A CYS 470 ? A CYS 470 
215 1 Y 1 A VAL 471 ? A VAL 471 
216 1 Y 1 B MET 1   ? B MET 1   
217 1 Y 1 B GLY 2   ? B GLY 2   
218 1 Y 1 B SER 3   ? B SER 3   
219 1 Y 1 B ILE 55  ? B ILE 55  
220 1 Y 1 B LEU 56  ? B LEU 56  
221 1 Y 1 B HIS 57  ? B HIS 57  
222 1 Y 1 B GLY 58  ? B GLY 58  
223 1 Y 1 B GLY 59  ? B GLY 59  
224 1 Y 1 B SER 60  ? B SER 60  
225 1 Y 1 B GLY 61  ? B GLY 61  
226 1 Y 1 B GLY 62  ? B GLY 62  
227 1 Y 1 B SER 63  ? B SER 63  
228 1 Y 1 B GLY 64  ? B GLY 64  
229 1 Y 1 B GLY 65  ? B GLY 65  
230 1 Y 1 C MET -17 ? C MET 1   
231 1 Y 1 C HIS -16 ? C HIS 2   
232 1 Y 1 C HIS -15 ? C HIS 3   
233 1 Y 1 C HIS -14 ? C HIS 4   
234 1 Y 1 C HIS -13 ? C HIS 5   
235 1 Y 1 C HIS -12 ? C HIS 6   
236 1 Y 1 C HIS -11 ? C HIS 7   
237 1 Y 1 C LEU -10 ? C LEU 8   
238 1 Y 1 C GLU -9  ? C GLU 9   
239 1 Y 1 C VAL -8  ? C VAL 10  
240 1 Y 1 C LEU -7  ? C LEU 11  
241 1 Y 1 C PHE -6  ? C PHE 12  
242 1 Y 1 C GLN -5  ? C GLN 13  
243 1 Y 1 C GLY -4  ? C GLY 14  
244 1 Y 1 C PRO -3  ? C PRO 15  
245 1 Y 1 C GLY -2  ? C GLY 16  
246 1 Y 1 C SER -1  ? C SER 17  
247 1 Y 1 C SER 0   ? C SER 18  
248 1 Y 1 C GLY 1   ? C GLY 19  
249 1 Y 1 C SER 2   ? C SER 20  
250 1 Y 1 D MET 1   ? D MET 1   
251 1 Y 1 D ALA 2   ? D ALA 2   
252 1 Y 1 D SER 3   ? D SER 3   
253 1 Y 1 D ASN 4   ? D ASN 4   
254 1 Y 1 D ASN 5   ? D ASN 5   
255 1 Y 1 D THR 6   ? D THR 6   
256 1 Y 1 D ALA 7   ? D ALA 7   
257 1 Y 1 D SER 8   ? D SER 8   
258 1 Y 1 D ARG 62  ? D ARG 62  
259 1 Y 1 D GLU 63  ? D GLU 63  
260 1 Y 1 D LYS 64  ? D LYS 64  
261 1 Y 1 D LYS 65  ? D LYS 65  
262 1 Y 1 D PHE 66  ? D PHE 66  
263 1 Y 1 D PHE 67  ? D PHE 67  
264 1 Y 1 D CYS 68  ? D CYS 68  
265 1 Y 1 D ALA 69  ? D ALA 69  
266 1 Y 1 D ILE 70  ? D ILE 70  
267 1 Y 1 D LEU 71  ? D LEU 71  
268 1 Y 1 E ASP 1   ? E ASP 1   
269 1 Y 1 E TRP 36  ? E TRP 36  
270 1 Y 1 E SER 119 A E SER 120 
271 1 Y 1 E SER 119 B E SER 121 
272 1 Y 1 E GLY 119 C E GLY 122 
273 1 Y 1 E GLY 119 D E GLY 123 
274 1 Y 1 E GLY 119 E E GLY 124 
275 1 Y 1 E GLY 119 F E GLY 125 
276 1 Y 1 E SER 119 G E SER 126 
277 1 Y 1 E GLY 119 H E GLY 127 
278 1 Y 1 E GLY 119 I E GLY 128 
279 1 Y 1 E GLY 119 J E GLY 129 
280 1 Y 1 E GLY 119 K E GLY 130 
281 1 Y 1 E SER 119 L E SER 131 
282 1 Y 1 E GLY 119 M E GLY 132 
283 1 Y 1 E GLY 119 N E GLY 133 
284 1 Y 1 E GLY 119 O E GLY 134 
285 1 Y 1 E GLY 119 P E GLY 135 
286 1 Y 1 E SER 119 Q E SER 136 
287 1 Y 1 E LYS 236 ? E LYS 248 
288 1 Y 1 E ALA 237 ? E ALA 249 
289 1 Y 1 E ALA 238 ? E ALA 250 
290 1 Y 1 E ALA 239 ? E ALA 251 
291 1 Y 1 E LEU 240 ? E LEU 252 
292 1 Y 1 E GLU 241 ? E GLU 253 
293 1 Y 1 E VAL 242 ? E VAL 254 
294 1 Y 1 E LEU 243 ? E LEU 255 
295 1 Y 1 E PHE 244 ? E PHE 256 
296 1 Y 1 E GLN 245 ? E GLN 257 
297 1 Y 1 E GLY 246 ? E GLY 258 
298 1 Y 1 E PRO 247 ? E PRO 259 
299 1 Y 1 E HIS 248 ? E HIS 260 
300 1 Y 1 E HIS 249 ? E HIS 261 
301 1 Y 1 E HIS 250 ? E HIS 262 
302 1 Y 1 E HIS 251 ? E HIS 263 
303 1 Y 1 E HIS 252 ? E HIS 264 
304 1 Y 1 E HIS 253 ? E HIS 265 
305 1 Y 1 E HIS 254 ? E HIS 266 
306 1 Y 1 E HIS 255 ? E HIS 267 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
SRO OH   O N N 301 
SRO CZ3  C Y N 302 
SRO CH2  C Y N 303 
SRO CZ2  C Y N 304 
SRO CE2  C Y N 305 
SRO NE1  N Y N 306 
SRO CD1  C Y N 307 
SRO CG   C Y N 308 
SRO CD2  C Y N 309 
SRO CE3  C Y N 310 
SRO CB   C N N 311 
SRO CA   C N N 312 
SRO NZ   N N N 313 
SRO HOH  H N N 314 
SRO HH2  H N N 315 
SRO HZ2  H N N 316 
SRO HNE1 H N N 317 
SRO HD1  H N N 318 
SRO HE3  H N N 319 
SRO HB1  H N N 320 
SRO HB2  H N N 321 
SRO HA1  H N N 322 
SRO HA2  H N N 323 
SRO HNZ1 H N N 324 
SRO HNZ2 H N N 325 
THR N    N N N 326 
THR CA   C N S 327 
THR C    C N N 328 
THR O    O N N 329 
THR CB   C N R 330 
THR OG1  O N N 331 
THR CG2  C N N 332 
THR OXT  O N N 333 
THR H    H N N 334 
THR H2   H N N 335 
THR HA   H N N 336 
THR HB   H N N 337 
THR HG1  H N N 338 
THR HG21 H N N 339 
THR HG22 H N N 340 
THR HG23 H N N 341 
THR HXT  H N N 342 
TRP N    N N N 343 
TRP CA   C N S 344 
TRP C    C N N 345 
TRP O    O N N 346 
TRP CB   C N N 347 
TRP CG   C Y N 348 
TRP CD1  C Y N 349 
TRP CD2  C Y N 350 
TRP NE1  N Y N 351 
TRP CE2  C Y N 352 
TRP CE3  C Y N 353 
TRP CZ2  C Y N 354 
TRP CZ3  C Y N 355 
TRP CH2  C Y N 356 
TRP OXT  O N N 357 
TRP H    H N N 358 
TRP H2   H N N 359 
TRP HA   H N N 360 
TRP HB2  H N N 361 
TRP HB3  H N N 362 
TRP HD1  H N N 363 
TRP HE1  H N N 364 
TRP HE3  H N N 365 
TRP HZ2  H N N 366 
TRP HZ3  H N N 367 
TRP HH2  H N N 368 
TRP HXT  H N N 369 
TYR N    N N N 370 
TYR CA   C N S 371 
TYR C    C N N 372 
TYR O    O N N 373 
TYR CB   C N N 374 
TYR CG   C Y N 375 
TYR CD1  C Y N 376 
TYR CD2  C Y N 377 
TYR CE1  C Y N 378 
TYR CE2  C Y N 379 
TYR CZ   C Y N 380 
TYR OH   O N N 381 
TYR OXT  O N N 382 
TYR H    H N N 383 
TYR H2   H N N 384 
TYR HA   H N N 385 
TYR HB2  H N N 386 
TYR HB3  H N N 387 
TYR HD1  H N N 388 
TYR HD2  H N N 389 
TYR HE1  H N N 390 
TYR HE2  H N N 391 
TYR HH   H N N 392 
TYR HXT  H N N 393 
VAL N    N N N 394 
VAL CA   C N S 395 
VAL C    C N N 396 
VAL O    O N N 397 
VAL CB   C N N 398 
VAL CG1  C N N 399 
VAL CG2  C N N 400 
VAL OXT  O N N 401 
VAL H    H N N 402 
VAL H2   H N N 403 
VAL HA   H N N 404 
VAL HB   H N N 405 
VAL HG11 H N N 406 
VAL HG12 H N N 407 
VAL HG13 H N N 408 
VAL HG21 H N N 409 
VAL HG22 H N N 410 
VAL HG23 H N N 411 
VAL HXT  H N N 412 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
SRO OH  CZ3  sing N N 288 
SRO OH  HOH  sing N N 289 
SRO CZ3 CE3  doub Y N 290 
SRO CZ3 CH2  sing Y N 291 
SRO CH2 CZ2  doub Y N 292 
SRO CH2 HH2  sing N N 293 
SRO CZ2 CE2  sing Y N 294 
SRO CZ2 HZ2  sing N N 295 
SRO CE2 NE1  sing Y N 296 
SRO CE2 CD2  doub Y N 297 
SRO NE1 CD1  sing Y N 298 
SRO NE1 HNE1 sing N N 299 
SRO CD1 CG   doub Y N 300 
SRO CD1 HD1  sing N N 301 
SRO CG  CB   sing N N 302 
SRO CG  CD2  sing Y N 303 
SRO CD2 CE3  sing Y N 304 
SRO CE3 HE3  sing N N 305 
SRO CB  CA   sing N N 306 
SRO CB  HB1  sing N N 307 
SRO CB  HB2  sing N N 308 
SRO CA  NZ   sing N N 309 
SRO CA  HA1  sing N N 310 
SRO CA  HA2  sing N N 311 
SRO NZ  HNZ1 sing N N 312 
SRO NZ  HNZ2 sing N N 313 
THR N   CA   sing N N 314 
THR N   H    sing N N 315 
THR N   H2   sing N N 316 
THR CA  C    sing N N 317 
THR CA  CB   sing N N 318 
THR CA  HA   sing N N 319 
THR C   O    doub N N 320 
THR C   OXT  sing N N 321 
THR CB  OG1  sing N N 322 
THR CB  CG2  sing N N 323 
THR CB  HB   sing N N 324 
THR OG1 HG1  sing N N 325 
THR CG2 HG21 sing N N 326 
THR CG2 HG22 sing N N 327 
THR CG2 HG23 sing N N 328 
THR OXT HXT  sing N N 329 
TRP N   CA   sing N N 330 
TRP N   H    sing N N 331 
TRP N   H2   sing N N 332 
TRP CA  C    sing N N 333 
TRP CA  CB   sing N N 334 
TRP CA  HA   sing N N 335 
TRP C   O    doub N N 336 
TRP C   OXT  sing N N 337 
TRP CB  CG   sing N N 338 
TRP CB  HB2  sing N N 339 
TRP CB  HB3  sing N N 340 
TRP CG  CD1  doub Y N 341 
TRP CG  CD2  sing Y N 342 
TRP CD1 NE1  sing Y N 343 
TRP CD1 HD1  sing N N 344 
TRP CD2 CE2  doub Y N 345 
TRP CD2 CE3  sing Y N 346 
TRP NE1 CE2  sing Y N 347 
TRP NE1 HE1  sing N N 348 
TRP CE2 CZ2  sing Y N 349 
TRP CE3 CZ3  doub Y N 350 
TRP CE3 HE3  sing N N 351 
TRP CZ2 CH2  doub Y N 352 
TRP CZ2 HZ2  sing N N 353 
TRP CZ3 CH2  sing Y N 354 
TRP CZ3 HZ3  sing N N 355 
TRP CH2 HH2  sing N N 356 
TRP OXT HXT  sing N N 357 
TYR N   CA   sing N N 358 
TYR N   H    sing N N 359 
TYR N   H2   sing N N 360 
TYR CA  C    sing N N 361 
TYR CA  CB   sing N N 362 
TYR CA  HA   sing N N 363 
TYR C   O    doub N N 364 
TYR C   OXT  sing N N 365 
TYR CB  CG   sing N N 366 
TYR CB  HB2  sing N N 367 
TYR CB  HB3  sing N N 368 
TYR CG  CD1  doub Y N 369 
TYR CG  CD2  sing Y N 370 
TYR CD1 CE1  sing Y N 371 
TYR CD1 HD1  sing N N 372 
TYR CD2 CE2  doub Y N 373 
TYR CD2 HD2  sing N N 374 
TYR CE1 CZ   doub Y N 375 
TYR CE1 HE1  sing N N 376 
TYR CE2 CZ   sing Y N 377 
TYR CE2 HE2  sing N N 378 
TYR CZ  OH   sing N N 379 
TYR OH  HH   sing N N 380 
TYR OXT HXT  sing N N 381 
VAL N   CA   sing N N 382 
VAL N   H    sing N N 383 
VAL N   H2   sing N N 384 
VAL CA  C    sing N N 385 
VAL CA  CB   sing N N 386 
VAL CA  HA   sing N N 387 
VAL C   O    doub N N 388 
VAL C   OXT  sing N N 389 
VAL CB  CG1  sing N N 390 
VAL CB  CG2  sing N N 391 
VAL CB  HB   sing N N 392 
VAL CG1 HG11 sing N N 393 
VAL CG1 HG12 sing N N 394 
VAL CG1 HG13 sing N N 395 
VAL CG2 HG21 sing N N 396 
VAL CG2 HG22 sing N N 397 
VAL CG2 HG23 sing N N 398 
VAL OXT HXT  sing N N 399 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-02-24 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9ARY 
_em_admin.last_update        2025-05-28 
_em_admin.map_release_date   2025-04-02 
_em_admin.title              
;Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
;
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         49.5 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Defense Advanced Research Projects Agency (DARPA)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           HR0011-20-2-0029 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9ARY 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LEU A 1 79  ? 158.929 132.829 171.017 1.00 63.16 ? 79  LEU A N   1 
ATOM   2    C CA  . LEU A 1 79  ? 157.659 133.439 171.386 1.00 61.21 ? 79  LEU A CA  1 
ATOM   3    C C   . LEU A 1 79  ? 156.547 132.902 170.488 1.00 59.19 ? 79  LEU A C   1 
ATOM   4    O O   . LEU A 1 79  ? 156.788 132.569 169.329 1.00 52.51 ? 79  LEU A O   1 
ATOM   5    C CB  . LEU A 1 79  ? 157.750 134.965 171.292 1.00 60.10 ? 79  LEU A CB  1 
ATOM   6    C CG  . LEU A 1 79  ? 156.652 135.799 171.952 1.00 61.31 ? 79  LEU A CG  1 
ATOM   7    C CD1 . LEU A 1 79  ? 156.671 135.605 173.460 1.00 57.74 ? 79  LEU A CD1 1 
ATOM   8    C CD2 . LEU A 1 79  ? 156.820 137.266 171.601 1.00 57.49 ? 79  LEU A CD2 1 
ATOM   9    N N   . LEU A 1 80  ? 155.334 132.809 171.041 1.00 60.40 ? 80  LEU A N   1 
ATOM   10   C CA  . LEU A 1 80  ? 154.211 132.253 170.291 1.00 55.12 ? 80  LEU A CA  1 
ATOM   11   C C   . LEU A 1 80  ? 153.755 133.197 169.186 1.00 55.16 ? 80  LEU A C   1 
ATOM   12   O O   . LEU A 1 80  ? 153.240 132.751 168.156 1.00 61.21 ? 80  LEU A O   1 
ATOM   13   C CB  . LEU A 1 80  ? 153.053 131.942 171.238 1.00 55.07 ? 80  LEU A CB  1 
ATOM   14   N N   . THR A 1 81  ? 153.941 134.506 169.378 1.00 51.12 ? 81  THR A N   1 
ATOM   15   C CA  . THR A 1 81  ? 153.526 135.467 168.360 1.00 53.31 ? 81  THR A CA  1 
ATOM   16   C C   . THR A 1 81  ? 154.502 135.510 167.192 1.00 57.67 ? 81  THR A C   1 
ATOM   17   O O   . THR A 1 81  ? 154.183 136.074 166.139 1.00 57.33 ? 81  THR A O   1 
ATOM   18   C CB  . THR A 1 81  ? 153.389 136.860 168.970 1.00 51.22 ? 81  THR A CB  1 
ATOM   19   O OG1 . THR A 1 81  ? 154.674 137.488 169.014 1.00 50.39 ? 81  THR A OG1 1 
ATOM   20   C CG2 . THR A 1 81  ? 152.835 136.772 170.379 1.00 52.72 ? 81  THR A CG2 1 
ATOM   21   N N   . ALA A 1 82  ? 155.696 134.935 167.359 1.00 59.92 ? 82  ALA A N   1 
ATOM   22   C CA  . ALA A 1 82  ? 156.680 134.936 166.283 1.00 57.58 ? 82  ALA A CA  1 
ATOM   23   C C   . ALA A 1 82  ? 156.290 133.984 165.161 1.00 57.23 ? 82  ALA A C   1 
ATOM   24   O O   . ALA A 1 82  ? 156.698 134.182 164.012 1.00 59.17 ? 82  ALA A O   1 
ATOM   25   C CB  . ALA A 1 82  ? 158.059 134.572 166.832 1.00 57.16 ? 82  ALA A CB  1 
ATOM   26   N N   . VAL A 1 83  ? 155.519 132.942 165.471 1.00 57.49 ? 83  VAL A N   1 
ATOM   27   C CA  . VAL A 1 83  ? 155.136 131.977 164.445 1.00 56.72 ? 83  VAL A CA  1 
ATOM   28   C C   . VAL A 1 83  ? 153.905 132.455 163.687 1.00 56.63 ? 83  VAL A C   1 
ATOM   29   O O   . VAL A 1 83  ? 153.682 132.065 162.535 1.00 56.10 ? 83  VAL A O   1 
ATOM   30   C CB  . VAL A 1 83  ? 154.908 130.592 165.076 1.00 53.76 ? 83  VAL A CB  1 
ATOM   31   N N   . VAL A 1 84  ? 153.084 133.296 164.322 1.00 53.47 ? 84  VAL A N   1 
ATOM   32   C CA  . VAL A 1 84  ? 151.801 133.687 163.743 1.00 55.78 ? 84  VAL A CA  1 
ATOM   33   C C   . VAL A 1 84  ? 151.999 134.627 162.555 1.00 59.11 ? 84  VAL A C   1 
ATOM   34   O O   . VAL A 1 84  ? 151.305 134.507 161.535 1.00 58.65 ? 84  VAL A O   1 
ATOM   35   C CB  . VAL A 1 84  ? 150.903 134.306 164.828 1.00 49.60 ? 84  VAL A CB  1 
ATOM   36   C CG1 . VAL A 1 84  ? 149.536 134.636 164.271 1.00 51.25 ? 84  VAL A CG1 1 
ATOM   37   C CG2 . VAL A 1 84  ? 150.770 133.354 165.999 1.00 50.53 ? 84  VAL A CG2 1 
ATOM   38   N N   . ILE A 1 85  ? 152.953 135.561 162.661 1.00 59.21 ? 85  ILE A N   1 
ATOM   39   C CA  . ILE A 1 85  ? 153.255 136.477 161.559 1.00 56.46 ? 85  ILE A CA  1 
ATOM   40   C C   . ILE A 1 85  ? 153.779 135.717 160.343 1.00 57.34 ? 85  ILE A C   1 
ATOM   41   O O   . ILE A 1 85  ? 153.353 135.971 159.206 1.00 60.18 ? 85  ILE A O   1 
ATOM   42   C CB  . ILE A 1 85  ? 154.243 137.569 162.023 1.00 58.62 ? 85  ILE A CB  1 
ATOM   43   C CG1 . ILE A 1 85  ? 155.367 136.979 162.882 1.00 56.93 ? 85  ILE A CG1 1 
ATOM   44   C CG2 . ILE A 1 85  ? 153.529 138.680 162.762 1.00 56.66 ? 85  ILE A CG2 1 
ATOM   45   C CD1 . ILE A 1 85  ? 156.325 138.002 163.448 1.00 57.49 ? 85  ILE A CD1 1 
ATOM   46   N N   . ILE A 1 86  ? 154.673 134.748 160.568 1.00 55.07 ? 86  ILE A N   1 
ATOM   47   C CA  . ILE A 1 86  ? 155.243 133.965 159.477 1.00 56.57 ? 86  ILE A CA  1 
ATOM   48   C C   . ILE A 1 86  ? 154.185 133.066 158.853 1.00 59.64 ? 86  ILE A C   1 
ATOM   49   O O   . ILE A 1 86  ? 154.128 132.920 157.626 1.00 59.18 ? 86  ILE A O   1 
ATOM   50   C CB  . ILE A 1 86  ? 156.452 133.155 159.979 1.00 54.32 ? 86  ILE A CB  1 
ATOM   51   N N   . LEU A 1 87  ? 153.318 132.473 159.683 1.00 51.19 ? 87  LEU A N   1 
ATOM   52   C CA  . LEU A 1 87  ? 152.244 131.626 159.175 1.00 50.21 ? 87  LEU A CA  1 
ATOM   53   C C   . LEU A 1 87  ? 151.238 132.413 158.347 1.00 53.20 ? 87  LEU A C   1 
ATOM   54   O O   . LEU A 1 87  ? 150.819 131.944 157.284 1.00 56.06 ? 87  LEU A O   1 
ATOM   55   C CB  . LEU A 1 87  ? 151.536 130.924 160.334 1.00 48.14 ? 87  LEU A CB  1 
ATOM   56   N N   . THR A 1 88  ? 150.870 133.619 158.794 1.00 47.25 ? 88  THR A N   1 
ATOM   57   C CA  . THR A 1 88  ? 149.935 134.449 158.038 1.00 48.73 ? 88  THR A CA  1 
ATOM   58   C C   . THR A 1 88  ? 150.535 134.909 156.713 1.00 51.64 ? 88  THR A C   1 
ATOM   59   O O   . THR A 1 88  ? 149.885 134.802 155.659 1.00 53.92 ? 88  THR A O   1 
ATOM   60   C CB  . THR A 1 88  ? 149.517 135.655 158.876 1.00 44.21 ? 88  THR A CB  1 
ATOM   61   O OG1 . THR A 1 88  ? 149.105 135.216 160.175 1.00 47.80 ? 88  THR A OG1 1 
ATOM   62   C CG2 . THR A 1 88  ? 148.374 136.398 158.211 1.00 43.92 ? 88  THR A CG2 1 
ATOM   63   N N   . ILE A 1 89  ? 151.783 135.393 156.746 1.00 49.69 ? 89  ILE A N   1 
ATOM   64   C CA  . ILE A 1 89  ? 152.426 135.915 155.543 1.00 47.18 ? 89  ILE A CA  1 
ATOM   65   C C   . ILE A 1 89  ? 152.709 134.797 154.547 1.00 51.77 ? 89  ILE A C   1 
ATOM   66   O O   . ILE A 1 89  ? 152.687 135.014 153.330 1.00 55.18 ? 89  ILE A O   1 
ATOM   67   C CB  . ILE A 1 89  ? 153.709 136.679 155.914 1.00 47.04 ? 89  ILE A CB  1 
ATOM   68   N N   . ALA A 1 90  ? 152.987 133.586 155.038 1.00 45.92 ? 90  ALA A N   1 
ATOM   69   C CA  . ALA A 1 90  ? 153.192 132.457 154.140 1.00 47.41 ? 90  ALA A CA  1 
ATOM   70   C C   . ALA A 1 90  ? 151.874 131.983 153.541 1.00 51.31 ? 90  ALA A C   1 
ATOM   71   O O   . ALA A 1 90  ? 151.775 131.769 152.326 1.00 53.27 ? 90  ALA A O   1 
ATOM   72   C CB  . ALA A 1 90  ? 153.891 131.318 154.883 1.00 46.17 ? 90  ALA A CB  1 
ATOM   73   N N   . GLY A 1 91  ? 150.844 131.828 154.384 1.00 42.50 ? 91  GLY A N   1 
ATOM   74   C CA  . GLY A 1 91  ? 149.592 131.249 153.926 1.00 40.13 ? 91  GLY A CA  1 
ATOM   75   C C   . GLY A 1 91  ? 148.850 132.129 152.941 1.00 45.47 ? 91  GLY A C   1 
ATOM   76   O O   . GLY A 1 91  ? 148.279 131.635 151.964 1.00 51.62 ? 91  GLY A O   1 
ATOM   77   N N   . ASN A 1 92  ? 148.876 133.447 153.157 1.00 42.57 ? 92  ASN A N   1 
ATOM   78   C CA  . ASN A 1 92  ? 148.124 134.319 152.261 1.00 43.05 ? 92  ASN A CA  1 
ATOM   79   C C   . ASN A 1 92  ? 148.820 134.450 150.913 1.00 46.57 ? 92  ASN A C   1 
ATOM   80   O O   . ASN A 1 92  ? 148.160 134.536 149.868 1.00 44.87 ? 92  ASN A O   1 
ATOM   81   C CB  . ASN A 1 92  ? 147.941 135.684 152.897 1.00 41.78 ? 92  ASN A CB  1 
ATOM   82   C CG  . ASN A 1 92  ? 146.995 135.638 154.053 1.00 44.31 ? 92  ASN A CG  1 
ATOM   83   O OD1 . ASN A 1 92  ? 146.898 134.627 154.736 1.00 42.80 ? 92  ASN A OD1 1 
ATOM   84   N ND2 . ASN A 1 92  ? 146.225 136.686 154.225 1.00 46.93 ? 92  ASN A ND2 1 
ATOM   85   N N   . ILE A 1 93  ? 150.155 134.451 150.925 1.00 50.17 ? 93  ILE A N   1 
ATOM   86   C CA  . ILE A 1 93  ? 150.926 134.445 149.688 1.00 48.98 ? 93  ILE A CA  1 
ATOM   87   C C   . ILE A 1 93  ? 150.691 133.151 148.923 1.00 49.83 ? 93  ILE A C   1 
ATOM   88   O O   . ILE A 1 93  ? 150.585 133.160 147.692 1.00 53.77 ? 93  ILE A O   1 
ATOM   89   C CB  . ILE A 1 93  ? 152.422 134.661 149.987 1.00 44.66 ? 93  ILE A CB  1 
ATOM   90   N N   . LEU A 1 94  ? 150.584 132.024 149.641 1.00 42.24 ? 94  LEU A N   1 
ATOM   91   C CA  . LEU A 1 94  ? 150.276 130.752 148.991 1.00 42.08 ? 94  LEU A CA  1 
ATOM   92   C C   . LEU A 1 94  ? 148.888 130.748 148.360 1.00 46.86 ? 94  LEU A C   1 
ATOM   93   O O   . LEU A 1 94  ? 148.723 130.240 147.246 1.00 50.84 ? 94  LEU A O   1 
ATOM   94   C CB  . LEU A 1 94  ? 150.392 129.602 149.990 1.00 44.95 ? 94  LEU A CB  1 
ATOM   95   C CG  . LEU A 1 94  ? 151.793 129.113 150.349 1.00 46.04 ? 94  LEU A CG  1 
ATOM   96   C CD1 . LEU A 1 94  ? 151.707 127.967 151.344 1.00 46.49 ? 94  LEU A CD1 1 
ATOM   97   C CD2 . LEU A 1 94  ? 152.556 128.700 149.106 1.00 46.79 ? 94  LEU A CD2 1 
ATOM   98   N N   . VAL A 1 95  ? 147.889 131.316 149.042 1.00 43.33 ? 95  VAL A N   1 
ATOM   99   C CA  . VAL A 1 95  ? 146.533 131.360 148.489 1.00 39.72 ? 95  VAL A CA  1 
ATOM   100  C C   . VAL A 1 95  ? 146.462 132.269 147.262 1.00 43.09 ? 95  VAL A C   1 
ATOM   101  O O   . VAL A 1 95  ? 145.847 131.910 146.247 1.00 47.03 ? 95  VAL A O   1 
ATOM   102  C CB  . VAL A 1 95  ? 145.529 131.777 149.578 1.00 41.61 ? 95  VAL A CB  1 
ATOM   103  C CG1 . VAL A 1 95  ? 144.149 131.994 148.997 1.00 39.16 ? 95  VAL A CG1 1 
ATOM   104  C CG2 . VAL A 1 95  ? 145.446 130.689 150.610 1.00 44.41 ? 95  VAL A CG2 1 
ATOM   105  N N   . ILE A 1 96  ? 147.107 133.440 147.318 1.00 43.53 ? 96  ILE A N   1 
ATOM   106  C CA  . ILE A 1 96  ? 147.079 134.349 146.172 1.00 44.97 ? 96  ILE A CA  1 
ATOM   107  C C   . ILE A 1 96  ? 147.869 133.769 144.996 1.00 44.27 ? 96  ILE A C   1 
ATOM   108  O O   . ILE A 1 96  ? 147.445 133.874 143.836 1.00 43.57 ? 96  ILE A O   1 
ATOM   109  C CB  . ILE A 1 96  ? 147.575 135.747 146.590 1.00 48.94 ? 96  ILE A CB  1 
ATOM   110  C CG1 . ILE A 1 96  ? 146.601 136.369 147.589 1.00 48.23 ? 96  ILE A CG1 1 
ATOM   111  C CG2 . ILE A 1 96  ? 147.689 136.687 145.403 1.00 46.01 ? 96  ILE A CG2 1 
ATOM   112  C CD1 . ILE A 1 96  ? 147.198 137.472 148.419 1.00 44.07 ? 96  ILE A CD1 1 
ATOM   113  N N   . MET A 1 97  ? 148.990 133.091 145.274 1.00 44.62 ? 97  MET A N   1 
ATOM   114  C CA  . MET A 1 97  ? 149.756 132.452 144.207 1.00 42.55 ? 97  MET A CA  1 
ATOM   115  C C   . MET A 1 97  ? 149.006 131.266 143.610 1.00 47.17 ? 97  MET A C   1 
ATOM   116  O O   . MET A 1 97  ? 149.128 130.990 142.412 1.00 53.65 ? 97  MET A O   1 
ATOM   117  C CB  . MET A 1 97  ? 151.122 132.012 144.732 1.00 38.53 ? 97  MET A CB  1 
ATOM   118  N N   . ALA A 1 98  ? 148.217 130.558 144.424 1.00 48.72 ? 98  ALA A N   1 
ATOM   119  C CA  . ALA A 1 98  ? 147.433 129.440 143.909 1.00 46.88 ? 98  ALA A CA  1 
ATOM   120  C C   . ALA A 1 98  ? 146.255 129.928 143.075 1.00 45.76 ? 98  ALA A C   1 
ATOM   121  O O   . ALA A 1 98  ? 145.843 129.262 142.120 1.00 47.40 ? 98  ALA A O   1 
ATOM   122  C CB  . ALA A 1 98  ? 146.951 128.560 145.061 1.00 46.23 ? 98  ALA A CB  1 
ATOM   123  N N   . VAL A 1 99  ? 145.682 131.079 143.438 1.00 44.81 ? 99  VAL A N   1 
ATOM   124  C CA  . VAL A 1 99  ? 144.617 131.660 142.623 1.00 47.01 ? 99  VAL A CA  1 
ATOM   125  C C   . VAL A 1 99  ? 145.180 132.170 141.301 1.00 51.25 ? 99  VAL A C   1 
ATOM   126  O O   . VAL A 1 99  ? 144.582 131.956 140.236 1.00 52.41 ? 99  VAL A O   1 
ATOM   127  C CB  . VAL A 1 99  ? 143.888 132.767 143.420 1.00 48.56 ? 99  VAL A CB  1 
ATOM   128  C CG1 . VAL A 1 99  ? 143.280 133.831 142.510 1.00 43.18 ? 99  VAL A CG1 1 
ATOM   129  C CG2 . VAL A 1 99  ? 142.816 132.162 144.300 1.00 48.87 ? 99  VAL A CG2 1 
ATOM   130  N N   . SER A 1 100 ? 146.352 132.810 141.336 1.00 52.82 ? 100 SER A N   1 
ATOM   131  C CA  . SER A 1 100 ? 146.939 133.372 140.122 1.00 50.41 ? 100 SER A CA  1 
ATOM   132  C C   . SER A 1 100 ? 147.466 132.283 139.190 1.00 53.23 ? 100 SER A C   1 
ATOM   133  O O   . SER A 1 100 ? 147.390 132.415 137.963 1.00 55.08 ? 100 SER A O   1 
ATOM   134  C CB  . SER A 1 100 ? 148.054 134.349 140.488 1.00 46.08 ? 100 SER A CB  1 
ATOM   135  O OG  . SER A 1 100 ? 147.583 135.334 141.388 1.00 50.44 ? 100 SER A OG  1 
ATOM   136  N N   . LEU A 1 101 ? 148.004 131.201 139.749 1.00 53.62 ? 101 LEU A N   1 
ATOM   137  C CA  . LEU A 1 101 ? 148.643 130.177 138.933 1.00 52.41 ? 101 LEU A CA  1 
ATOM   138  C C   . LEU A 1 101 ? 147.669 129.148 138.377 1.00 54.32 ? 101 LEU A C   1 
ATOM   139  O O   . LEU A 1 101 ? 147.782 128.779 137.203 1.00 57.64 ? 101 LEU A O   1 
ATOM   140  C CB  . LEU A 1 101 ? 149.729 129.458 139.738 1.00 53.37 ? 101 LEU A CB  1 
ATOM   141  C CG  . LEU A 1 101 ? 151.180 129.867 139.473 1.00 53.99 ? 101 LEU A CG  1 
ATOM   142  C CD1 . LEU A 1 101 ? 151.636 129.337 138.122 1.00 54.40 ? 101 LEU A CD1 1 
ATOM   143  C CD2 . LEU A 1 101 ? 151.370 131.376 139.552 1.00 50.27 ? 101 LEU A CD2 1 
ATOM   144  N N   . GLU A 1 102 ? 146.724 128.669 139.180 1.00 54.73 ? 102 GLU A N   1 
ATOM   145  C CA  . GLU A 1 102 ? 145.786 127.642 138.730 1.00 55.76 ? 102 GLU A CA  1 
ATOM   146  C C   . GLU A 1 102 ? 144.686 128.312 137.915 1.00 58.54 ? 102 GLU A C   1 
ATOM   147  O O   . GLU A 1 102 ? 143.978 129.193 138.407 1.00 57.08 ? 102 GLU A O   1 
ATOM   148  C CB  . GLU A 1 102 ? 145.214 126.876 139.916 1.00 51.97 ? 102 GLU A CB  1 
ATOM   149  N N   . LYS A 1 103 ? 144.541 127.891 136.657 1.00 57.97 ? 103 LYS A N   1 
ATOM   150  C CA  . LYS A 1 103 ? 143.529 128.480 135.787 1.00 57.78 ? 103 LYS A CA  1 
ATOM   151  C C   . LYS A 1 103 ? 142.126 127.992 136.117 1.00 57.58 ? 103 LYS A C   1 
ATOM   152  O O   . LYS A 1 103 ? 141.150 128.646 135.738 1.00 58.79 ? 103 LYS A O   1 
ATOM   153  C CB  . LYS A 1 103 ? 143.854 128.175 134.324 1.00 55.89 ? 103 LYS A CB  1 
ATOM   154  N N   . LYS A 1 104 ? 142.002 126.859 136.812 1.00 55.54 ? 104 LYS A N   1 
ATOM   155  C CA  . LYS A 1 104 ? 140.687 126.337 137.160 1.00 55.48 ? 104 LYS A CA  1 
ATOM   156  C C   . LYS A 1 104 ? 140.035 127.113 138.294 1.00 58.98 ? 104 LYS A C   1 
ATOM   157  O O   . LYS A 1 104 ? 138.822 126.991 138.492 1.00 61.03 ? 104 LYS A O   1 
ATOM   158  C CB  . LYS A 1 104 ? 140.792 124.860 137.541 1.00 55.74 ? 104 LYS A CB  1 
ATOM   159  N N   . LEU A 1 105 ? 140.805 127.904 139.038 1.00 57.82 ? 105 LEU A N   1 
ATOM   160  C CA  . LEU A 1 105 ? 140.298 128.659 140.175 1.00 53.63 ? 105 LEU A CA  1 
ATOM   161  C C   . LEU A 1 105 ? 139.974 130.106 139.830 1.00 53.05 ? 105 LEU A C   1 
ATOM   162  O O   . LEU A 1 105 ? 140.095 130.976 140.694 1.00 53.58 ? 105 LEU A O   1 
ATOM   163  C CB  . LEU A 1 105 ? 141.307 128.610 141.323 1.00 49.13 ? 105 LEU A CB  1 
ATOM   164  C CG  . LEU A 1 105 ? 141.745 127.203 141.729 1.00 49.36 ? 105 LEU A CG  1 
ATOM   165  C CD1 . LEU A 1 105 ? 142.768 127.257 142.843 1.00 55.71 ? 105 LEU A CD1 1 
ATOM   166  C CD2 . LEU A 1 105 ? 140.545 126.380 142.149 1.00 50.95 ? 105 LEU A CD2 1 
ATOM   167  N N   . GLN A 1 106 ? 139.587 130.388 138.590 1.00 60.89 ? 106 GLN A N   1 
ATOM   168  C CA  . GLN A 1 106 ? 139.210 131.741 138.189 1.00 60.11 ? 106 GLN A CA  1 
ATOM   169  C C   . GLN A 1 106 ? 137.690 131.839 138.188 1.00 63.09 ? 106 GLN A C   1 
ATOM   170  O O   . GLN A 1 106 ? 137.024 131.364 137.266 1.00 66.04 ? 106 GLN A O   1 
ATOM   171  C CB  . GLN A 1 106 ? 139.790 132.077 136.821 1.00 61.01 ? 106 GLN A CB  1 
ATOM   172  N N   . ASN A 1 107 ? 137.137 132.463 139.224 1.00 60.45 ? 107 ASN A N   1 
ATOM   173  C CA  . ASN A 1 107 ? 135.695 132.613 139.351 1.00 59.08 ? 107 ASN A CA  1 
ATOM   174  C C   . ASN A 1 107 ? 135.407 133.820 140.229 1.00 61.58 ? 107 ASN A C   1 
ATOM   175  O O   . ASN A 1 107 ? 136.319 134.531 140.658 1.00 59.14 ? 107 ASN A O   1 
ATOM   176  C CB  . ASN A 1 107 ? 135.044 131.352 139.930 1.00 54.05 ? 107 ASN A CB  1 
ATOM   177  N N   . ALA A 1 108 ? 134.117 134.050 140.477 1.00 54.91 ? 108 ALA A N   1 
ATOM   178  C CA  . ALA A 1 108 ? 133.711 135.160 141.333 1.00 53.10 ? 108 ALA A CA  1 
ATOM   179  C C   . ALA A 1 108 ? 134.038 134.882 142.796 1.00 52.78 ? 108 ALA A C   1 
ATOM   180  O O   . ALA A 1 108 ? 134.556 135.759 143.506 1.00 54.32 ? 108 ALA A O   1 
ATOM   181  C CB  . ALA A 1 108 ? 132.216 135.421 141.155 1.00 50.68 ? 108 ALA A CB  1 
ATOM   182  N N   . THR A 1 109 ? 133.741 133.663 143.256 1.00 53.25 ? 109 THR A N   1 
ATOM   183  C CA  . THR A 1 109 ? 133.956 133.292 144.652 1.00 56.69 ? 109 THR A CA  1 
ATOM   184  C C   . THR A 1 109 ? 135.438 133.285 144.998 1.00 59.30 ? 109 THR A C   1 
ATOM   185  O O   . THR A 1 109 ? 135.839 133.721 146.084 1.00 64.57 ? 109 THR A O   1 
ATOM   186  C CB  . THR A 1 109 ? 133.341 131.920 144.921 1.00 55.66 ? 109 THR A CB  1 
ATOM   187  O OG1 . THR A 1 109 ? 132.038 131.855 144.328 1.00 56.91 ? 109 THR A OG1 1 
ATOM   188  C CG2 . THR A 1 109 ? 133.222 131.675 146.415 1.00 58.04 ? 109 THR A CG2 1 
ATOM   189  N N   . ASN A 1 110 ? 136.272 132.819 144.070 1.00 51.62 ? 110 ASN A N   1 
ATOM   190  C CA  . ASN A 1 110 ? 137.704 132.799 144.324 1.00 48.25 ? 110 ASN A CA  1 
ATOM   191  C C   . ASN A 1 110 ? 138.308 134.194 144.245 1.00 51.91 ? 110 ASN A C   1 
ATOM   192  O O   . ASN A 1 110 ? 139.311 134.466 144.909 1.00 56.39 ? 110 ASN A O   1 
ATOM   193  C CB  . ASN A 1 110 ? 138.388 131.854 143.348 1.00 51.40 ? 110 ASN A CB  1 
ATOM   194  C CG  . ASN A 1 110 ? 138.155 130.403 143.697 1.00 59.07 ? 110 ASN A CG  1 
ATOM   195  O OD1 . ASN A 1 110 ? 138.998 129.758 144.316 1.00 61.52 ? 110 ASN A OD1 1 
ATOM   196  N ND2 . ASN A 1 110 ? 136.999 129.880 143.308 1.00 58.45 ? 110 ASN A ND2 1 
ATOM   197  N N   . TYR A 1 111 ? 137.699 135.097 143.472 1.00 49.49 ? 111 TYR A N   1 
ATOM   198  C CA  . TYR A 1 111 ? 138.122 136.495 143.486 1.00 47.45 ? 111 TYR A CA  1 
ATOM   199  C C   . TYR A 1 111 ? 137.807 137.150 144.827 1.00 44.94 ? 111 TYR A C   1 
ATOM   200  O O   . TYR A 1 111 ? 138.624 137.906 145.371 1.00 46.32 ? 111 TYR A O   1 
ATOM   201  C CB  . TYR A 1 111 ? 137.450 137.256 142.343 1.00 47.75 ? 111 TYR A CB  1 
ATOM   202  N N   . PHE A 1 112 ? 136.620 136.863 145.377 1.00 43.15 ? 112 PHE A N   1 
ATOM   203  C CA  . PHE A 1 112 ? 136.270 137.354 146.710 1.00 38.85 ? 112 PHE A CA  1 
ATOM   204  C C   . PHE A 1 112 ? 137.194 136.769 147.775 1.00 40.27 ? 112 PHE A C   1 
ATOM   205  O O   . PHE A 1 112 ? 137.597 137.467 148.716 1.00 47.00 ? 112 PHE A O   1 
ATOM   206  C CB  . PHE A 1 112 ? 134.813 137.011 147.016 1.00 41.79 ? 112 PHE A CB  1 
ATOM   207  C CG  . PHE A 1 112 ? 134.128 137.978 147.947 1.00 43.19 ? 112 PHE A CG  1 
ATOM   208  C CD1 . PHE A 1 112 ? 134.802 139.058 148.493 1.00 42.47 ? 112 PHE A CD1 1 
ATOM   209  C CD2 . PHE A 1 112 ? 132.791 137.802 148.265 1.00 44.50 ? 112 PHE A CD2 1 
ATOM   210  C CE1 . PHE A 1 112 ? 134.157 139.934 149.342 1.00 44.75 ? 112 PHE A CE1 1 
ATOM   211  C CE2 . PHE A 1 112 ? 132.143 138.677 149.111 1.00 42.44 ? 112 PHE A CE2 1 
ATOM   212  C CZ  . PHE A 1 112 ? 132.828 139.742 149.650 1.00 44.03 ? 112 PHE A CZ  1 
ATOM   213  N N   . LEU A 1 113 ? 137.551 135.494 147.632 1.00 35.16 ? 113 LEU A N   1 
ATOM   214  C CA  . LEU A 1 113 ? 138.478 134.865 148.567 1.00 36.36 ? 113 LEU A CA  1 
ATOM   215  C C   . LEU A 1 113 ? 139.888 135.440 148.444 1.00 39.68 ? 113 LEU A C   1 
ATOM   216  O O   . LEU A 1 113 ? 140.603 135.555 149.448 1.00 38.29 ? 113 LEU A O   1 
ATOM   217  C CB  . LEU A 1 113 ? 138.460 133.356 148.336 1.00 33.25 ? 113 LEU A CB  1 
ATOM   218  C CG  . LEU A 1 113 ? 139.396 132.437 149.104 1.00 37.37 ? 113 LEU A CG  1 
ATOM   219  C CD1 . LEU A 1 113 ? 138.599 131.263 149.615 1.00 36.22 ? 113 LEU A CD1 1 
ATOM   220  C CD2 . LEU A 1 113 ? 140.495 131.965 148.183 1.00 41.68 ? 113 LEU A CD2 1 
ATOM   221  N N   . MET A 1 114 ? 140.299 135.825 147.232 1.00 42.88 ? 114 MET A N   1 
ATOM   222  C CA  . MET A 1 114 ? 141.575 136.512 147.053 1.00 40.41 ? 114 MET A CA  1 
ATOM   223  C C   . MET A 1 114 ? 141.555 137.894 147.693 1.00 44.89 ? 114 MET A C   1 
ATOM   224  O O   . MET A 1 114 ? 142.567 138.342 148.237 1.00 51.88 ? 114 MET A O   1 
ATOM   225  C CB  . MET A 1 114 ? 141.914 136.623 145.568 1.00 45.23 ? 114 MET A CB  1 
ATOM   226  C CG  . MET A 1 114 ? 143.338 137.075 145.288 1.00 45.88 ? 114 MET A CG  1 
ATOM   227  S SD  . MET A 1 114 ? 143.661 137.347 143.536 1.00 60.85 ? 114 MET A SD  1 
ATOM   228  C CE  . MET A 1 114 ? 143.447 139.121 143.425 1.00 46.92 ? 114 MET A CE  1 
ATOM   229  N N   . SER A 1 115 ? 140.411 138.583 147.632 1.00 42.90 ? 115 SER A N   1 
ATOM   230  C CA  . SER A 1 115 ? 140.272 139.859 148.336 1.00 38.90 ? 115 SER A CA  1 
ATOM   231  C C   . SER A 1 115 ? 140.361 139.674 149.848 1.00 41.51 ? 115 SER A C   1 
ATOM   232  O O   . SER A 1 115 ? 140.956 140.504 150.552 1.00 38.42 ? 115 SER A O   1 
ATOM   233  C CB  . SER A 1 115 ? 138.952 140.526 147.956 1.00 35.18 ? 115 SER A CB  1 
ATOM   234  O OG  . SER A 1 115 ? 138.718 141.671 148.751 1.00 39.77 ? 115 SER A OG  1 
ATOM   235  N N   . LEU A 1 116 ? 139.775 138.585 150.358 1.00 39.89 ? 116 LEU A N   1 
ATOM   236  C CA  . LEU A 1 116 ? 139.884 138.244 151.777 1.00 33.90 ? 116 LEU A CA  1 
ATOM   237  C C   . LEU A 1 116 ? 141.337 137.995 152.173 1.00 39.21 ? 116 LEU A C   1 
ATOM   238  O O   . LEU A 1 116 ? 141.803 138.470 153.218 1.00 44.74 ? 116 LEU A O   1 
ATOM   239  C CB  . LEU A 1 116 ? 139.040 137.001 152.068 1.00 35.97 ? 116 LEU A CB  1 
ATOM   240  C CG  . LEU A 1 116 ? 138.271 136.786 153.374 1.00 39.06 ? 116 LEU A CG  1 
ATOM   241  C CD1 . LEU A 1 116 ? 137.482 135.501 153.273 1.00 43.19 ? 116 LEU A CD1 1 
ATOM   242  C CD2 . LEU A 1 116 ? 139.131 136.768 154.613 1.00 37.10 ? 116 LEU A CD2 1 
ATOM   243  N N   . ALA A 1 117 ? 142.066 137.250 151.337 1.00 39.30 ? 117 ALA A N   1 
ATOM   244  C CA  . ALA A 1 117 ? 143.475 136.977 151.600 1.00 39.50 ? 117 ALA A CA  1 
ATOM   245  C C   . ALA A 1 117 ? 144.325 138.239 151.507 1.00 38.58 ? 117 ALA A C   1 
ATOM   246  O O   . ALA A 1 117 ? 145.296 138.378 152.255 1.00 35.08 ? 117 ALA A O   1 
ATOM   247  C CB  . ALA A 1 117 ? 143.994 135.915 150.635 1.00 39.10 ? 117 ALA A CB  1 
ATOM   248  N N   . ILE A 1 118 ? 143.963 139.165 150.615 1.00 41.45 ? 118 ILE A N   1 
ATOM   249  C CA  . ILE A 1 118 ? 144.638 140.460 150.531 1.00 36.39 ? 118 ILE A CA  1 
ATOM   250  C C   . ILE A 1 118 ? 144.439 141.250 151.821 1.00 43.29 ? 118 ILE A C   1 
ATOM   251  O O   . ILE A 1 118 ? 145.391 141.833 152.360 1.00 48.60 ? 118 ILE A O   1 
ATOM   252  C CB  . ILE A 1 118 ? 144.139 141.235 149.294 1.00 39.50 ? 118 ILE A CB  1 
ATOM   253  C CG1 . ILE A 1 118 ? 144.850 140.739 148.032 1.00 42.27 ? 118 ILE A CG1 1 
ATOM   254  C CG2 . ILE A 1 118 ? 144.302 142.746 149.448 1.00 41.99 ? 118 ILE A CG2 1 
ATOM   255  C CD1 . ILE A 1 118 ? 146.306 141.151 147.941 1.00 44.04 ? 118 ILE A CD1 1 
ATOM   256  N N   . ALA A 1 119 ? 143.206 141.254 152.346 1.00 47.62 ? 119 ALA A N   1 
ATOM   257  C CA  . ALA A 1 119 ? 142.909 141.975 153.586 1.00 44.66 ? 119 ALA A CA  1 
ATOM   258  C C   . ALA A 1 119 ? 143.677 141.400 154.774 1.00 42.10 ? 119 ALA A C   1 
ATOM   259  O O   . ALA A 1 119 ? 144.295 142.144 155.549 1.00 44.44 ? 119 ALA A O   1 
ATOM   260  C CB  . ALA A 1 119 ? 141.407 141.949 153.860 1.00 39.20 ? 119 ALA A CB  1 
ATOM   261  N N   . ASP A 1 120 ? 143.695 140.070 154.908 1.00 39.83 ? 120 ASP A N   1 
ATOM   262  C CA  . ASP A 1 120 ? 144.435 139.491 156.030 1.00 41.26 ? 120 ASP A CA  1 
ATOM   263  C C   . ASP A 1 120 ? 145.947 139.567 155.834 1.00 45.48 ? 120 ASP A C   1 
ATOM   264  O O   . ASP A 1 120 ? 146.688 139.598 156.822 1.00 46.44 ? 120 ASP A O   1 
ATOM   265  C CB  . ASP A 1 120 ? 144.025 138.044 156.287 1.00 43.28 ? 120 ASP A CB  1 
ATOM   266  C CG  . ASP A 1 120 ? 142.552 137.813 156.128 1.00 47.86 ? 120 ASP A CG  1 
ATOM   267  O OD1 . ASP A 1 120 ? 141.763 138.743 156.390 1.00 48.42 ? 120 ASP A OD1 1 
ATOM   268  O OD2 . ASP A 1 120 ? 142.186 136.690 155.733 1.00 52.07 ? 120 ASP A OD2 1 
ATOM   269  N N   . MET A 1 121 ? 146.431 139.616 154.590 1.00 47.19 ? 121 MET A N   1 
ATOM   270  C CA  . MET A 1 121 ? 147.869 139.743 154.376 1.00 48.73 ? 121 MET A CA  1 
ATOM   271  C C   . MET A 1 121 ? 148.336 141.151 154.696 1.00 46.90 ? 121 MET A C   1 
ATOM   272  O O   . MET A 1 121 ? 149.419 141.344 155.261 1.00 48.19 ? 121 MET A O   1 
ATOM   273  C CB  . MET A 1 121 ? 148.229 139.373 152.939 1.00 48.33 ? 121 MET A CB  1 
ATOM   274  C CG  . MET A 1 121 ? 149.698 139.055 152.741 1.00 45.41 ? 121 MET A CG  1 
ATOM   275  S SD  . MET A 1 121 ? 150.157 139.036 151.003 1.00 64.50 ? 121 MET A SD  1 
ATOM   276  C CE  . MET A 1 121 ? 149.604 140.664 150.506 1.00 46.81 ? 121 MET A CE  1 
ATOM   277  N N   . LEU A 1 122 ? 147.518 142.148 154.346 1.00 37.88 ? 122 LEU A N   1 
ATOM   278  C CA  . LEU A 1 122 ? 147.798 143.518 154.751 1.00 37.13 ? 122 LEU A CA  1 
ATOM   279  C C   . LEU A 1 122 ? 147.755 143.658 156.267 1.00 45.68 ? 122 LEU A C   1 
ATOM   280  O O   . LEU A 1 122 ? 148.585 144.368 156.849 1.00 51.01 ? 122 LEU A O   1 
ATOM   281  C CB  . LEU A 1 122 ? 146.807 144.470 154.088 1.00 40.35 ? 122 LEU A CB  1 
ATOM   282  C CG  . LEU A 1 122 ? 147.047 144.769 152.609 1.00 40.46 ? 122 LEU A CG  1 
ATOM   283  C CD1 . LEU A 1 122 ? 145.871 145.533 152.023 1.00 41.78 ? 122 LEU A CD1 1 
ATOM   284  C CD2 . LEU A 1 122 ? 148.343 145.537 152.420 1.00 38.99 ? 122 LEU A CD2 1 
ATOM   285  N N   . LEU A 1 123 ? 146.814 142.961 156.923 1.00 43.31 ? 123 LEU A N   1 
ATOM   286  C CA  . LEU A 1 123 ? 146.780 142.927 158.387 1.00 43.76 ? 123 LEU A CA  1 
ATOM   287  C C   . LEU A 1 123 ? 148.054 142.333 158.979 1.00 39.27 ? 123 LEU A C   1 
ATOM   288  O O   . LEU A 1 123 ? 148.715 142.966 159.812 1.00 41.25 ? 123 LEU A O   1 
ATOM   289  C CB  . LEU A 1 123 ? 145.569 142.126 158.867 1.00 40.58 ? 123 LEU A CB  1 
ATOM   290  C CG  . LEU A 1 123 ? 145.405 142.063 160.388 1.00 40.07 ? 123 LEU A CG  1 
ATOM   291  C CD1 . LEU A 1 123 ? 144.341 143.017 160.891 1.00 42.05 ? 123 LEU A CD1 1 
ATOM   292  C CD2 . LEU A 1 123 ? 145.108 140.651 160.839 1.00 42.48 ? 123 LEU A CD2 1 
ATOM   293  N N   . GLY A 1 124 ? 148.437 141.138 158.523 1.00 36.39 ? 124 GLY A N   1 
ATOM   294  C CA  . GLY A 1 124 ? 149.597 140.452 159.062 1.00 41.58 ? 124 GLY A CA  1 
ATOM   295  C C   . GLY A 1 124 ? 150.921 141.090 158.704 1.00 37.76 ? 124 GLY A C   1 
ATOM   296  O O   . GLY A 1 124 ? 151.929 140.807 159.359 1.00 36.69 ? 124 GLY A O   1 
ATOM   297  N N   . PHE A 1 125 ? 150.946 141.935 157.676 1.00 39.57 ? 125 PHE A N   1 
ATOM   298  C CA  . PHE A 1 125 ? 152.152 142.667 157.319 1.00 44.91 ? 125 PHE A CA  1 
ATOM   299  C C   . PHE A 1 125 ? 152.239 144.022 158.008 1.00 43.53 ? 125 PHE A C   1 
ATOM   300  O O   . PHE A 1 125 ? 153.341 144.494 158.299 1.00 44.94 ? 125 PHE A O   1 
ATOM   301  C CB  . PHE A 1 125 ? 152.223 142.849 155.797 1.00 41.77 ? 125 PHE A CB  1 
ATOM   302  N N   . LEU A 1 126 ? 151.103 144.657 158.290 1.00 36.08 ? 126 LEU A N   1 
ATOM   303  C CA  . LEU A 1 126 ? 151.154 146.036 158.750 1.00 34.16 ? 126 LEU A CA  1 
ATOM   304  C C   . LEU A 1 126 ? 150.932 146.176 160.253 1.00 35.73 ? 126 LEU A C   1 
ATOM   305  O O   . LEU A 1 126 ? 151.624 146.965 160.901 1.00 36.03 ? 126 LEU A O   1 
ATOM   306  C CB  . LEU A 1 126 ? 150.134 146.880 157.974 1.00 35.92 ? 126 LEU A CB  1 
ATOM   307  C CG  . LEU A 1 126 ? 150.611 147.649 156.733 1.00 35.43 ? 126 LEU A CG  1 
ATOM   308  C CD1 . LEU A 1 126 ? 151.220 146.743 155.679 1.00 36.41 ? 126 LEU A CD1 1 
ATOM   309  C CD2 . LEU A 1 126 ? 149.467 148.435 156.128 1.00 36.23 ? 126 LEU A CD2 1 
ATOM   310  N N   . VAL A 1 127 ? 149.985 145.442 160.833 1.00 39.48 ? 127 VAL A N   1 
ATOM   311  C CA  . VAL A 1 127 ? 149.622 145.707 162.226 1.00 37.30 ? 127 VAL A CA  1 
ATOM   312  C C   . VAL A 1 127 ? 150.152 144.632 163.163 1.00 35.14 ? 127 VAL A C   1 
ATOM   313  O O   . VAL A 1 127 ? 150.210 144.829 164.379 1.00 37.77 ? 127 VAL A O   1 
ATOM   314  C CB  . VAL A 1 127 ? 148.091 145.864 162.361 1.00 41.16 ? 127 VAL A CB  1 
ATOM   315  C CG1 . VAL A 1 127 ? 147.545 146.704 161.229 1.00 40.01 ? 127 VAL A CG1 1 
ATOM   316  C CG2 . VAL A 1 127 ? 147.394 144.523 162.438 1.00 38.24 ? 127 VAL A CG2 1 
ATOM   317  N N   . MET A 1 128 ? 150.549 143.478 162.625 1.00 33.05 ? 128 MET A N   1 
ATOM   318  C CA  . MET A 1 128 ? 150.855 142.343 163.494 1.00 30.76 ? 128 MET A CA  1 
ATOM   319  C C   . MET A 1 128 ? 152.277 142.390 164.062 1.00 36.17 ? 128 MET A C   1 
ATOM   320  O O   . MET A 1 128 ? 152.433 142.132 165.271 1.00 47.28 ? 128 MET A O   1 
ATOM   321  C CB  . MET A 1 128 ? 150.529 141.039 162.754 1.00 36.00 ? 128 MET A CB  1 
ATOM   322  C CG  . MET A 1 128 ? 149.032 140.743 162.720 1.00 40.51 ? 128 MET A CG  1 
ATOM   323  S SD  . MET A 1 128 ? 148.515 139.018 162.677 1.00 34.22 ? 128 MET A SD  1 
ATOM   324  C CE  . MET A 1 128 ? 149.937 138.201 163.359 1.00 39.69 ? 128 MET A CE  1 
ATOM   325  N N   . PRO A 1 129 ? 153.344 142.707 163.297 1.00 39.37 ? 129 PRO A N   1 
ATOM   326  C CA  . PRO A 1 129 ? 154.634 142.944 163.971 1.00 41.23 ? 129 PRO A CA  1 
ATOM   327  C C   . PRO A 1 129 ? 154.657 144.196 164.833 1.00 45.30 ? 129 PRO A C   1 
ATOM   328  O O   . PRO A 1 129 ? 155.462 144.263 165.767 1.00 46.42 ? 129 PRO A O   1 
ATOM   329  C CB  . PRO A 1 129 ? 155.635 143.042 162.813 1.00 43.81 ? 129 PRO A CB  1 
ATOM   330  C CG  . PRO A 1 129 ? 154.830 143.375 161.642 1.00 46.53 ? 129 PRO A CG  1 
ATOM   331  C CD  . PRO A 1 129 ? 153.561 142.634 161.835 1.00 43.81 ? 129 PRO A CD  1 
ATOM   332  N N   . VAL A 1 130 ? 153.798 145.181 164.557 1.00 47.50 ? 130 VAL A N   1 
ATOM   333  C CA  . VAL A 1 130 ? 153.656 146.331 165.450 1.00 44.43 ? 130 VAL A CA  1 
ATOM   334  C C   . VAL A 1 130 ? 153.104 145.889 166.801 1.00 45.35 ? 130 VAL A C   1 
ATOM   335  O O   . VAL A 1 130 ? 153.577 146.326 167.858 1.00 52.07 ? 130 VAL A O   1 
ATOM   336  C CB  . VAL A 1 130 ? 152.769 147.407 164.791 1.00 40.39 ? 130 VAL A CB  1 
ATOM   337  C CG1 . VAL A 1 130 ? 152.518 148.570 165.735 1.00 43.83 ? 130 VAL A CG1 1 
ATOM   338  C CG2 . VAL A 1 130 ? 153.414 147.904 163.518 1.00 42.14 ? 130 VAL A CG2 1 
ATOM   339  N N   . SER A 1 131 ? 152.112 144.994 166.786 1.00 43.84 ? 131 SER A N   1 
ATOM   340  C CA  . SER A 1 131 ? 151.568 144.456 168.028 1.00 44.41 ? 131 SER A CA  1 
ATOM   341  C C   . SER A 1 131 ? 152.586 143.578 168.749 1.00 43.64 ? 131 SER A C   1 
ATOM   342  O O   . SER A 1 131 ? 152.641 143.573 169.985 1.00 45.41 ? 131 SER A O   1 
ATOM   343  C CB  . SER A 1 131 ? 150.287 143.678 167.738 1.00 43.49 ? 131 SER A CB  1 
ATOM   344  O OG  . SER A 1 131 ? 149.585 143.391 168.933 1.00 43.80 ? 131 SER A OG  1 
ATOM   345  N N   . MET A 1 132 ? 153.411 142.843 167.993 1.00 48.56 ? 132 MET A N   1 
ATOM   346  C CA  . MET A 1 132 ? 154.504 142.086 168.605 1.00 46.26 ? 132 MET A CA  1 
ATOM   347  C C   . MET A 1 132 ? 155.530 143.012 169.252 1.00 45.91 ? 132 MET A C   1 
ATOM   348  O O   . MET A 1 132 ? 156.064 142.708 170.325 1.00 45.17 ? 132 MET A O   1 
ATOM   349  C CB  . MET A 1 132 ? 155.176 141.197 167.559 1.00 49.77 ? 132 MET A CB  1 
ATOM   350  C CG  . MET A 1 132 ? 156.294 140.325 168.106 1.00 48.86 ? 132 MET A CG  1 
ATOM   351  S SD  . MET A 1 132 ? 157.532 139.912 166.864 1.00 59.77 ? 132 MET A SD  1 
ATOM   352  C CE  . MET A 1 132 ? 158.712 138.997 167.853 1.00 50.51 ? 132 MET A CE  1 
ATOM   353  N N   . LEU A 1 133 ? 155.818 144.145 168.606 1.00 52.73 ? 133 LEU A N   1 
ATOM   354  C CA  . LEU A 1 133 ? 156.731 145.139 169.164 1.00 56.64 ? 133 LEU A CA  1 
ATOM   355  C C   . LEU A 1 133 ? 156.161 145.762 170.433 1.00 63.89 ? 133 LEU A C   1 
ATOM   356  O O   . LEU A 1 133 ? 156.902 146.050 171.381 1.00 64.39 ? 133 LEU A O   1 
ATOM   357  C CB  . LEU A 1 133 ? 157.013 146.214 168.114 1.00 52.70 ? 133 LEU A CB  1 
ATOM   358  C CG  . LEU A 1 133 ? 157.841 147.431 168.514 1.00 58.47 ? 133 LEU A CG  1 
ATOM   359  C CD1 . LEU A 1 133 ? 159.300 147.042 168.668 1.00 60.50 ? 133 LEU A CD1 1 
ATOM   360  C CD2 . LEU A 1 133 ? 157.676 148.549 167.498 1.00 58.61 ? 133 LEU A CD2 1 
ATOM   361  N N   . THR A 1 134 ? 154.845 145.986 170.456 1.00 65.69 ? 134 THR A N   1 
ATOM   362  C CA  . THR A 1 134 ? 154.173 146.470 171.659 1.00 56.86 ? 134 THR A CA  1 
ATOM   363  C C   . THR A 1 134 ? 154.260 145.442 172.783 1.00 58.60 ? 134 THR A C   1 
ATOM   364  O O   . THR A 1 134 ? 154.437 145.797 173.954 1.00 60.13 ? 134 THR A O   1 
ATOM   365  C CB  . THR A 1 134 ? 152.715 146.798 171.331 1.00 53.09 ? 134 THR A CB  1 
ATOM   366  O OG1 . THR A 1 134 ? 152.671 147.706 170.225 1.00 57.20 ? 134 THR A OG1 1 
ATOM   367  C CG2 . THR A 1 134 ? 152.019 147.442 172.511 1.00 57.60 ? 134 THR A CG2 1 
ATOM   368  N N   . ILE A 1 135 ? 154.144 144.156 172.434 1.00 57.64 ? 135 ILE A N   1 
ATOM   369  C CA  . ILE A 1 135 ? 154.289 143.075 173.411 1.00 52.21 ? 135 ILE A CA  1 
ATOM   370  C C   . ILE A 1 135 ? 155.706 143.035 173.976 1.00 53.70 ? 135 ILE A C   1 
ATOM   371  O O   . ILE A 1 135 ? 155.901 142.932 175.194 1.00 57.18 ? 135 ILE A O   1 
ATOM   372  C CB  . ILE A 1 135 ? 153.887 141.732 172.769 1.00 57.32 ? 135 ILE A CB  1 
ATOM   373  C CG1 . ILE A 1 135 ? 152.368 141.606 172.731 1.00 56.02 ? 135 ILE A CG1 1 
ATOM   374  C CG2 . ILE A 1 135 ? 154.493 140.540 173.501 1.00 56.29 ? 135 ILE A CG2 1 
ATOM   375  C CD1 . ILE A 1 135 ? 151.758 141.546 174.099 1.00 53.79 ? 135 ILE A CD1 1 
ATOM   376  N N   . LEU A 1 136 ? 156.715 143.156 173.107 1.00 59.05 ? 136 LEU A N   1 
ATOM   377  C CA  . LEU A 1 136 ? 158.104 143.003 173.532 1.00 63.76 ? 136 LEU A CA  1 
ATOM   378  C C   . LEU A 1 136 ? 158.600 144.172 174.377 1.00 65.03 ? 136 LEU A C   1 
ATOM   379  O O   . LEU A 1 136 ? 159.625 144.038 175.054 1.00 65.63 ? 136 LEU A O   1 
ATOM   380  C CB  . LEU A 1 136 ? 159.009 142.830 172.311 1.00 62.15 ? 136 LEU A CB  1 
ATOM   381  N N   . TYR A 1 137 ? 157.905 145.309 174.353 1.00 67.50 ? 137 TYR A N   1 
ATOM   382  C CA  . TYR A 1 137 ? 158.251 146.455 175.182 1.00 68.29 ? 137 TYR A CA  1 
ATOM   383  C C   . TYR A 1 137 ? 157.358 146.582 176.411 1.00 68.69 ? 137 TYR A C   1 
ATOM   384  O O   . TYR A 1 137 ? 157.487 147.554 177.161 1.00 74.05 ? 137 TYR A O   1 
ATOM   385  C CB  . TYR A 1 137 ? 158.197 147.739 174.355 1.00 70.13 ? 137 TYR A CB  1 
ATOM   386  C CG  . TYR A 1 137 ? 159.482 148.048 173.626 1.00 68.48 ? 137 TYR A CG  1 
ATOM   387  C CD1 . TYR A 1 137 ? 159.876 147.301 172.522 1.00 67.66 ? 137 TYR A CD1 1 
ATOM   388  C CD2 . TYR A 1 137 ? 160.296 149.099 174.033 1.00 67.46 ? 137 TYR A CD2 1 
ATOM   389  C CE1 . TYR A 1 137 ? 161.050 147.588 171.849 1.00 70.99 ? 137 TYR A CE1 1 
ATOM   390  C CE2 . TYR A 1 137 ? 161.471 149.393 173.368 1.00 69.71 ? 137 TYR A CE2 1 
ATOM   391  C CZ  . TYR A 1 137 ? 161.843 148.634 172.277 1.00 73.51 ? 137 TYR A CZ  1 
ATOM   392  O OH  . TYR A 1 137 ? 163.012 148.921 171.612 1.00 72.72 ? 137 TYR A OH  1 
ATOM   393  N N   . GLY A 1 138 ? 156.476 145.613 176.643 1.00 65.33 ? 138 GLY A N   1 
ATOM   394  C CA  . GLY A 1 138 ? 155.572 145.680 177.780 1.00 69.14 ? 138 GLY A CA  1 
ATOM   395  C C   . GLY A 1 138 ? 154.541 146.782 177.698 1.00 68.90 ? 138 GLY A C   1 
ATOM   396  O O   . GLY A 1 138 ? 154.337 147.504 178.681 1.00 70.60 ? 138 GLY A O   1 
ATOM   397  N N   . TYR A 1 139 ? 153.920 146.960 176.530 1.00 66.07 ? 139 TYR A N   1 
ATOM   398  C CA  . TYR A 1 139 ? 152.831 147.887 176.212 1.00 66.94 ? 139 TYR A CA  1 
ATOM   399  C C   . TYR A 1 139 ? 153.214 149.362 176.322 1.00 69.43 ? 139 TYR A C   1 
ATOM   400  O O   . TYR A 1 139 ? 152.329 150.219 176.214 1.00 69.71 ? 139 TYR A O   1 
ATOM   401  C CB  . TYR A 1 139 ? 151.573 147.634 177.058 1.00 63.99 ? 139 TYR A CB  1 
ATOM   402  N N   . ARG A 1 140 ? 154.488 149.693 176.525 1.00 68.86 ? 140 ARG A N   1 
ATOM   403  C CA  . ARG A 1 140 ? 154.966 151.070 176.408 1.00 68.73 ? 140 ARG A CA  1 
ATOM   404  C C   . ARG A 1 140 ? 155.419 151.261 174.968 1.00 71.68 ? 140 ARG A C   1 
ATOM   405  O O   . ARG A 1 140 ? 156.343 150.589 174.504 1.00 72.20 ? 140 ARG A O   1 
ATOM   406  C CB  . ARG A 1 140 ? 156.093 151.341 177.396 1.00 67.12 ? 140 ARG A CB  1 
ATOM   407  N N   . TRP A 1 141 ? 154.772 152.174 174.255 1.00 72.31 ? 141 TRP A N   1 
ATOM   408  C CA  . TRP A 1 141 ? 154.843 152.168 172.798 1.00 70.25 ? 141 TRP A CA  1 
ATOM   409  C C   . TRP A 1 141 ? 156.155 152.784 172.324 1.00 69.21 ? 141 TRP A C   1 
ATOM   410  O O   . TRP A 1 141 ? 156.439 153.941 172.661 1.00 72.47 ? 141 TRP A O   1 
ATOM   411  C CB  . TRP A 1 141 ? 153.672 152.937 172.204 1.00 68.19 ? 141 TRP A CB  1 
ATOM   412  C CG  . TRP A 1 141 ? 153.364 152.498 170.818 1.00 72.70 ? 141 TRP A CG  1 
ATOM   413  C CD1 . TRP A 1 141 ? 153.516 151.241 170.313 1.00 75.52 ? 141 TRP A CD1 1 
ATOM   414  C CD2 . TRP A 1 141 ? 152.937 153.315 169.729 1.00 71.33 ? 141 TRP A CD2 1 
ATOM   415  N NE1 . TRP A 1 141 ? 153.160 151.211 168.991 1.00 73.52 ? 141 TRP A NE1 1 
ATOM   416  C CE2 . TRP A 1 141 ? 152.807 152.476 168.604 1.00 72.35 ? 141 TRP A CE2 1 
ATOM   417  C CE3 . TRP A 1 141 ? 152.632 154.670 169.597 1.00 69.21 ? 141 TRP A CE3 1 
ATOM   418  C CZ2 . TRP A 1 141 ? 152.389 152.945 167.371 1.00 69.49 ? 141 TRP A CZ2 1 
ATOM   419  C CZ3 . TRP A 1 141 ? 152.215 155.131 168.373 1.00 69.90 ? 141 TRP A CZ3 1 
ATOM   420  C CH2 . TRP A 1 141 ? 152.106 154.273 167.273 1.00 71.13 ? 141 TRP A CH2 1 
ATOM   421  N N   . PRO A 1 142 ? 156.977 152.068 171.550 1.00 70.59 ? 142 PRO A N   1 
ATOM   422  C CA  . PRO A 1 142 ? 158.261 152.634 171.107 1.00 73.04 ? 142 PRO A CA  1 
ATOM   423  C C   . PRO A 1 142 ? 158.122 153.610 169.950 1.00 75.16 ? 142 PRO A C   1 
ATOM   424  O O   . PRO A 1 142 ? 158.876 154.583 169.854 1.00 78.13 ? 142 PRO A O   1 
ATOM   425  C CB  . PRO A 1 142 ? 159.060 151.395 170.678 1.00 73.96 ? 142 PRO A CB  1 
ATOM   426  C CG  . PRO A 1 142 ? 158.261 150.215 171.163 1.00 75.25 ? 142 PRO A CG  1 
ATOM   427  C CD  . PRO A 1 142 ? 156.850 150.658 171.157 1.00 73.10 ? 142 PRO A CD  1 
ATOM   428  N N   . LEU A 1 143 ? 157.174 153.335 169.057 1.00 71.31 ? 143 LEU A N   1 
ATOM   429  C CA  . LEU A 1 143 ? 156.915 154.175 167.901 1.00 71.69 ? 143 LEU A CA  1 
ATOM   430  C C   . LEU A 1 143 ? 156.357 155.526 168.357 1.00 74.96 ? 143 LEU A C   1 
ATOM   431  O O   . LEU A 1 143 ? 155.682 155.600 169.384 1.00 74.75 ? 143 LEU A O   1 
ATOM   432  C CB  . LEU A 1 143 ? 155.943 153.452 166.966 1.00 71.88 ? 143 LEU A CB  1 
ATOM   433  N N   . PRO A 1 144 ? 156.640 156.615 167.636 1.00 75.35 ? 144 PRO A N   1 
ATOM   434  C CA  . PRO A 1 144 ? 156.234 157.931 168.146 1.00 74.27 ? 144 PRO A CA  1 
ATOM   435  C C   . PRO A 1 144 ? 154.747 158.241 167.988 1.00 73.69 ? 144 PRO A C   1 
ATOM   436  O O   . PRO A 1 144 ? 153.998 157.524 167.320 1.00 75.20 ? 144 PRO A O   1 
ATOM   437  C CB  . PRO A 1 144 ? 157.140 158.887 167.351 1.00 74.07 ? 144 PRO A CB  1 
ATOM   438  C CG  . PRO A 1 144 ? 157.731 157.976 166.205 1.00 73.94 ? 144 PRO A CG  1 
ATOM   439  C CD  . PRO A 1 144 ? 156.844 156.805 166.189 1.00 72.41 ? 144 PRO A CD  1 
ATOM   440  N N   . SER A 1 145 ? 154.317 159.322 168.645 1.00 73.94 ? 145 SER A N   1 
ATOM   441  C CA  . SER A 1 145 ? 152.898 159.508 168.940 1.00 75.10 ? 145 SER A CA  1 
ATOM   442  C C   . SER A 1 145 ? 152.096 159.906 167.707 1.00 75.24 ? 145 SER A C   1 
ATOM   443  O O   . SER A 1 145 ? 150.860 159.871 167.728 1.00 78.18 ? 145 SER A O   1 
ATOM   444  C CB  . SER A 1 145 ? 152.736 160.550 170.044 1.00 75.06 ? 145 SER A CB  1 
ATOM   445  O OG  . SER A 1 145 ? 153.502 160.197 171.183 1.00 74.76 ? 145 SER A OG  1 
ATOM   446  N N   . LYS A 1 146 ? 152.773 160.291 166.624 1.00 75.35 ? 146 LYS A N   1 
ATOM   447  C CA  . LYS A 1 146 ? 152.065 160.647 165.401 1.00 76.54 ? 146 LYS A CA  1 
ATOM   448  C C   . LYS A 1 146 ? 151.475 159.432 164.695 1.00 76.33 ? 146 LYS A C   1 
ATOM   449  O O   . LYS A 1 146 ? 150.565 159.590 163.875 1.00 75.19 ? 146 LYS A O   1 
ATOM   450  C CB  . LYS A 1 146 ? 153.002 161.397 164.453 1.00 76.14 ? 146 LYS A CB  1 
ATOM   451  N N   . LEU A 1 147 ? 151.968 158.227 164.988 1.00 73.78 ? 147 LEU A N   1 
ATOM   452  C CA  . LEU A 1 147 ? 151.533 157.054 164.239 1.00 73.97 ? 147 LEU A CA  1 
ATOM   453  C C   . LEU A 1 147 ? 150.508 156.207 164.984 1.00 74.44 ? 147 LEU A C   1 
ATOM   454  O O   . LEU A 1 147 ? 150.272 155.063 164.583 1.00 71.55 ? 147 LEU A O   1 
ATOM   455  C CB  . LEU A 1 147 ? 152.738 156.186 163.876 1.00 70.94 ? 147 LEU A CB  1 
ATOM   456  C CG  . LEU A 1 147 ? 153.710 156.772 162.853 1.00 71.94 ? 147 LEU A CG  1 
ATOM   457  C CD1 . LEU A 1 147 ? 154.814 155.775 162.531 1.00 72.08 ? 147 LEU A CD1 1 
ATOM   458  C CD2 . LEU A 1 147 ? 152.965 157.196 161.594 1.00 72.41 ? 147 LEU A CD2 1 
ATOM   459  N N   . CYS A 1 148 ? 149.915 156.713 166.067 1.00 71.38 ? 148 CYS A N   1 
ATOM   460  C CA  . CYS A 1 148 ? 148.971 155.886 166.814 1.00 71.20 ? 148 CYS A CA  1 
ATOM   461  C C   . CYS A 1 148 ? 147.618 155.824 166.124 1.00 69.11 ? 148 CYS A C   1 
ATOM   462  O O   . CYS A 1 148 ? 146.990 154.762 166.077 1.00 67.02 ? 148 CYS A O   1 
ATOM   463  C CB  . CYS A 1 148 ? 148.817 156.400 168.241 1.00 68.58 ? 148 CYS A CB  1 
ATOM   464  S SG  . CYS A 1 148 ? 147.856 155.291 169.299 1.00 80.92 ? 148 CYS A SG  1 
ATOM   465  N N   . ALA A 1 149 ? 147.159 156.946 165.566 1.00 59.60 ? 149 ALA A N   1 
ATOM   466  C CA  . ALA A 1 149 ? 145.817 156.993 164.997 1.00 54.97 ? 149 ALA A CA  1 
ATOM   467  C C   . ALA A 1 149 ? 145.726 156.231 163.684 1.00 55.30 ? 149 ALA A C   1 
ATOM   468  O O   . ALA A 1 149 ? 144.623 155.886 163.247 1.00 56.26 ? 149 ALA A O   1 
ATOM   469  C CB  . ALA A 1 149 ? 145.386 158.441 164.791 1.00 57.64 ? 149 ALA A CB  1 
ATOM   470  N N   . VAL A 1 150 ? 146.860 155.965 163.039 1.00 60.32 ? 150 VAL A N   1 
ATOM   471  C CA  . VAL A 1 150 ? 146.827 155.195 161.803 1.00 57.69 ? 150 VAL A CA  1 
ATOM   472  C C   . VAL A 1 150 ? 146.953 153.706 162.090 1.00 58.33 ? 150 VAL A C   1 
ATOM   473  O O   . VAL A 1 150 ? 146.530 152.878 161.281 1.00 59.91 ? 150 VAL A O   1 
ATOM   474  C CB  . VAL A 1 150 ? 147.913 155.682 160.827 1.00 57.15 ? 150 VAL A CB  1 
ATOM   475  C CG1 . VAL A 1 150 ? 147.533 157.037 160.254 1.00 59.31 ? 150 VAL A CG1 1 
ATOM   476  C CG2 . VAL A 1 150 ? 149.259 155.751 161.515 1.00 53.91 ? 150 VAL A CG2 1 
ATOM   477  N N   . TRP A 1 151 ? 147.524 153.334 163.240 1.00 53.95 ? 151 TRP A N   1 
ATOM   478  C CA  . TRP A 1 151 ? 147.613 151.916 163.577 1.00 49.68 ? 151 TRP A CA  1 
ATOM   479  C C   . TRP A 1 151 ? 146.251 151.368 163.982 1.00 49.33 ? 151 TRP A C   1 
ATOM   480  O O   . TRP A 1 151 ? 145.875 150.261 163.575 1.00 49.80 ? 151 TRP A O   1 
ATOM   481  C CB  . TRP A 1 151 ? 148.641 151.693 164.684 1.00 48.53 ? 151 TRP A CB  1 
ATOM   482  C CG  . TRP A 1 151 ? 148.696 150.280 165.177 1.00 52.26 ? 151 TRP A CG  1 
ATOM   483  C CD1 . TRP A 1 151 ? 149.180 149.201 164.500 1.00 52.19 ? 151 TRP A CD1 1 
ATOM   484  C CD2 . TRP A 1 151 ? 148.289 149.795 166.463 1.00 52.98 ? 151 TRP A CD2 1 
ATOM   485  N NE1 . TRP A 1 151 ? 149.083 148.071 165.275 1.00 47.18 ? 151 TRP A NE1 1 
ATOM   486  C CE2 . TRP A 1 151 ? 148.540 148.409 166.486 1.00 46.84 ? 151 TRP A CE2 1 
ATOM   487  C CE3 . TRP A 1 151 ? 147.731 150.395 167.594 1.00 54.36 ? 151 TRP A CE3 1 
ATOM   488  C CZ2 . TRP A 1 151 ? 148.251 147.617 167.592 1.00 46.66 ? 151 TRP A CZ2 1 
ATOM   489  C CZ3 . TRP A 1 151 ? 147.442 149.605 168.691 1.00 52.55 ? 151 TRP A CZ3 1 
ATOM   490  C CH2 . TRP A 1 151 ? 147.704 148.232 168.682 1.00 49.12 ? 151 TRP A CH2 1 
ATOM   491  N N   . ILE A 1 152 ? 145.484 152.148 164.753 1.00 48.54 ? 152 ILE A N   1 
ATOM   492  C CA  . ILE A 1 152 ? 144.096 151.790 165.045 1.00 49.40 ? 152 ILE A CA  1 
ATOM   493  C C   . ILE A 1 152 ? 143.265 151.805 163.770 1.00 47.35 ? 152 ILE A C   1 
ATOM   494  O O   . ILE A 1 152 ? 142.369 150.974 163.589 1.00 49.25 ? 152 ILE A O   1 
ATOM   495  C CB  . ILE A 1 152 ? 143.497 152.728 166.110 1.00 47.58 ? 152 ILE A CB  1 
ATOM   496  C CG1 . ILE A 1 152 ? 144.508 153.038 167.216 1.00 44.76 ? 152 ILE A CG1 1 
ATOM   497  C CG2 . ILE A 1 152 ? 142.203 152.149 166.663 1.00 45.96 ? 152 ILE A CG2 1 
ATOM   498  C CD1 . ILE A 1 152 ? 144.591 152.005 168.312 1.00 50.10 ? 152 ILE A CD1 1 
ATOM   499  N N   . TYR A 1 153 ? 143.556 152.749 162.866 1.00 44.23 ? 153 TYR A N   1 
ATOM   500  C CA  . TYR A 1 153 ? 142.871 152.806 161.575 1.00 42.22 ? 153 TYR A CA  1 
ATOM   501  C C   . TYR A 1 153 ? 143.105 151.552 160.747 1.00 42.12 ? 153 TYR A C   1 
ATOM   502  O O   . TYR A 1 153 ? 142.150 150.969 160.224 1.00 39.04 ? 153 TYR A O   1 
ATOM   503  C CB  . TYR A 1 153 ? 143.323 154.030 160.786 1.00 47.10 ? 153 TYR A CB  1 
ATOM   504  C CG  . TYR A 1 153 ? 142.441 154.318 159.598 1.00 50.03 ? 153 TYR A CG  1 
ATOM   505  C CD1 . TYR A 1 153 ? 141.061 154.347 159.725 1.00 44.90 ? 153 TYR A CD1 1 
ATOM   506  C CD2 . TYR A 1 153 ? 142.992 154.524 158.339 1.00 49.22 ? 153 TYR A CD2 1 
ATOM   507  C CE1 . TYR A 1 153 ? 140.254 154.597 158.635 1.00 47.67 ? 153 TYR A CE1 1 
ATOM   508  C CE2 . TYR A 1 153 ? 142.190 154.774 157.244 1.00 49.77 ? 153 TYR A CE2 1 
ATOM   509  C CZ  . TYR A 1 153 ? 140.820 154.809 157.402 1.00 52.32 ? 153 TYR A CZ  1 
ATOM   510  O OH  . TYR A 1 153 ? 140.004 155.057 156.325 1.00 55.18 ? 153 TYR A OH  1 
ATOM   511  N N   . LEU A 1 154 ? 144.361 151.114 160.641 1.00 41.26 ? 154 LEU A N   1 
ATOM   512  C CA  . LEU A 1 154 ? 144.673 149.913 159.875 1.00 38.68 ? 154 LEU A CA  1 
ATOM   513  C C   . LEU A 1 154 ? 144.089 148.672 160.534 1.00 40.72 ? 154 LEU A C   1 
ATOM   514  O O   . LEU A 1 154 ? 143.557 147.794 159.844 1.00 42.47 ? 154 LEU A O   1 
ATOM   515  C CB  . LEU A 1 154 ? 146.185 149.774 159.713 1.00 35.91 ? 154 LEU A CB  1 
ATOM   516  C CG  . LEU A 1 154 ? 146.888 150.747 158.768 1.00 37.57 ? 154 LEU A CG  1 
ATOM   517  C CD1 . LEU A 1 154 ? 148.393 150.670 158.960 1.00 39.79 ? 154 LEU A CD1 1 
ATOM   518  C CD2 . LEU A 1 154 ? 146.508 150.487 157.325 1.00 40.23 ? 154 LEU A CD2 1 
ATOM   519  N N   . ASP A 1 155 ? 144.136 148.608 161.871 1.00 43.20 ? 155 ASP A N   1 
ATOM   520  C CA  . ASP A 1 155 ? 143.605 147.457 162.596 1.00 39.19 ? 155 ASP A CA  1 
ATOM   521  C C   . ASP A 1 155 ? 142.094 147.332 162.420 1.00 37.41 ? 155 ASP A C   1 
ATOM   522  O O   . ASP A 1 155 ? 141.591 146.266 162.043 1.00 39.60 ? 155 ASP A O   1 
ATOM   523  C CB  . ASP A 1 155 ? 143.965 147.577 164.075 1.00 36.51 ? 155 ASP A CB  1 
ATOM   524  C CG  . ASP A 1 155 ? 144.105 146.235 164.752 1.00 44.71 ? 155 ASP A CG  1 
ATOM   525  O OD1 . ASP A 1 155 ? 143.248 145.357 164.534 1.00 44.79 ? 155 ASP A OD1 1 
ATOM   526  O OD2 . ASP A 1 155 ? 145.074 146.062 165.516 1.00 49.82 ? 155 ASP A OD2 1 
ATOM   527  N N   . VAL A 1 156 ? 141.361 148.427 162.651 1.00 34.78 ? 156 VAL A N   1 
ATOM   528  C CA  . VAL A 1 156 ? 139.905 148.409 162.529 1.00 30.63 ? 156 VAL A CA  1 
ATOM   529  C C   . VAL A 1 156 ? 139.489 148.218 161.074 1.00 32.54 ? 156 VAL A C   1 
ATOM   530  O O   . VAL A 1 156 ? 138.545 147.474 160.786 1.00 35.82 ? 156 VAL A O   1 
ATOM   531  C CB  . VAL A 1 156 ? 139.304 149.687 163.149 1.00 30.66 ? 156 VAL A CB  1 
ATOM   532  C CG1 . VAL A 1 156 ? 137.809 149.779 162.907 1.00 28.01 ? 156 VAL A CG1 1 
ATOM   533  C CG2 . VAL A 1 156 ? 139.557 149.705 164.644 1.00 34.22 ? 156 VAL A CG2 1 
ATOM   534  N N   . LEU A 1 157 ? 140.232 148.817 160.135 1.00 32.02 ? 157 LEU A N   1 
ATOM   535  C CA  . LEU A 1 157 ? 139.909 148.707 158.715 1.00 32.72 ? 157 LEU A CA  1 
ATOM   536  C C   . LEU A 1 157 ? 140.070 147.278 158.213 1.00 35.23 ? 157 LEU A C   1 
ATOM   537  O O   . LEU A 1 157 ? 139.155 146.720 157.598 1.00 37.63 ? 157 LEU A O   1 
ATOM   538  C CB  . LEU A 1 157 ? 140.795 149.661 157.911 1.00 36.45 ? 157 LEU A CB  1 
ATOM   539  C CG  . LEU A 1 157 ? 140.725 149.588 156.386 1.00 39.83 ? 157 LEU A CG  1 
ATOM   540  C CD1 . LEU A 1 157 ? 139.346 149.978 155.891 1.00 37.83 ? 157 LEU A CD1 1 
ATOM   541  C CD2 . LEU A 1 157 ? 141.790 150.471 155.760 1.00 35.14 ? 157 LEU A CD2 1 
ATOM   542  N N   . PHE A 1 158 ? 141.210 146.648 158.511 1.00 35.22 ? 158 PHE A N   1 
ATOM   543  C CA  . PHE A 1 158 ? 141.438 145.296 158.017 1.00 31.30 ? 158 PHE A CA  1 
ATOM   544  C C   . PHE A 1 158 ? 140.588 144.268 158.757 1.00 31.84 ? 158 PHE A C   1 
ATOM   545  O O   . PHE A 1 158 ? 140.114 143.307 158.138 1.00 36.97 ? 158 PHE A O   1 
ATOM   546  C CB  . PHE A 1 158 ? 142.922 144.947 158.112 1.00 31.11 ? 158 PHE A CB  1 
ATOM   547  C CG  . PHE A 1 158 ? 143.807 145.808 157.253 1.00 28.71 ? 158 PHE A CG  1 
ATOM   548  C CD1 . PHE A 1 158 ? 143.341 146.332 156.057 1.00 30.59 ? 158 PHE A CD1 1 
ATOM   549  C CD2 . PHE A 1 158 ? 145.109 146.081 157.636 1.00 27.16 ? 158 PHE A CD2 1 
ATOM   550  C CE1 . PHE A 1 158 ? 144.153 147.122 155.268 1.00 29.27 ? 158 PHE A CE1 1 
ATOM   551  C CE2 . PHE A 1 158 ? 145.924 146.868 156.851 1.00 28.29 ? 158 PHE A CE2 1 
ATOM   552  C CZ  . PHE A 1 158 ? 145.444 147.390 155.668 1.00 29.87 ? 158 PHE A CZ  1 
ATOM   553  N N   . SER A 1 159 ? 140.343 144.465 160.060 1.00 30.25 ? 159 SER A N   1 
ATOM   554  C CA  . SER A 1 159 ? 139.500 143.528 160.796 1.00 27.89 ? 159 SER A CA  1 
ATOM   555  C C   . SER A 1 159 ? 138.038 143.630 160.374 1.00 32.59 ? 159 SER A C   1 
ATOM   556  O O   . SER A 1 159 ? 137.362 142.604 160.225 1.00 38.16 ? 159 SER A O   1 
ATOM   557  C CB  . SER A 1 159 ? 139.652 143.764 162.295 1.00 26.06 ? 159 SER A CB  1 
ATOM   558  O OG  . SER A 1 159 ? 141.017 143.746 162.665 1.00 31.60 ? 159 SER A OG  1 
ATOM   559  N N   . THR A 1 160 ? 137.534 144.850 160.156 1.00 29.86 ? 160 THR A N   1 
ATOM   560  C CA  . THR A 1 160 ? 136.175 145.017 159.656 1.00 27.01 ? 160 THR A CA  1 
ATOM   561  C C   . THR A 1 160 ? 136.053 144.506 158.227 1.00 32.62 ? 160 THR A C   1 
ATOM   562  O O   . THR A 1 160 ? 135.008 143.968 157.843 1.00 37.51 ? 160 THR A O   1 
ATOM   563  C CB  . THR A 1 160 ? 135.766 146.488 159.738 1.00 31.74 ? 160 THR A CB  1 
ATOM   564  O OG1 . THR A 1 160 ? 136.154 147.019 161.010 1.00 35.71 ? 160 THR A OG1 1 
ATOM   565  C CG2 . THR A 1 160 ? 134.264 146.643 159.580 1.00 31.97 ? 160 THR A CG2 1 
ATOM   566  N N   . ALA A 1 161 ? 137.124 144.641 157.436 1.00 29.49 ? 161 ALA A N   1 
ATOM   567  C CA  . ALA A 1 161 ? 137.144 144.079 156.091 1.00 29.85 ? 161 ALA A CA  1 
ATOM   568  C C   . ALA A 1 161 ? 137.031 142.563 156.125 1.00 32.21 ? 161 ALA A C   1 
ATOM   569  O O   . ALA A 1 161 ? 136.245 141.977 155.374 1.00 33.37 ? 161 ALA A O   1 
ATOM   570  C CB  . ALA A 1 161 ? 138.421 144.508 155.370 1.00 32.79 ? 161 ALA A CB  1 
ATOM   571  N N   . SER A 1 162 ? 137.778 141.917 157.025 1.00 30.21 ? 162 SER A N   1 
ATOM   572  C CA  . SER A 1 162 ? 137.711 140.464 157.161 1.00 22.77 ? 162 SER A CA  1 
ATOM   573  C C   . SER A 1 162 ? 136.337 140.002 157.642 1.00 27.41 ? 162 SER A C   1 
ATOM   574  O O   . SER A 1 162 ? 135.772 139.042 157.104 1.00 41.29 ? 162 SER A O   1 
ATOM   575  C CB  . SER A 1 162 ? 138.805 139.985 158.112 1.00 27.70 ? 162 SER A CB  1 
ATOM   576  O OG  . SER A 1 162 ? 138.882 138.573 158.123 1.00 39.94 ? 162 SER A OG  1 
ATOM   577  N N   . ILE A 1 163 ? 135.769 140.701 158.632 1.00 23.93 ? 163 ILE A N   1 
ATOM   578  C CA  . ILE A 1 163 ? 134.476 140.303 159.196 1.00 29.21 ? 163 ILE A CA  1 
ATOM   579  C C   . ILE A 1 163 ? 133.358 140.477 158.170 1.00 27.87 ? 163 ILE A C   1 
ATOM   580  O O   . ILE A 1 163 ? 132.507 139.593 157.998 1.00 30.35 ? 163 ILE A O   1 
ATOM   581  C CB  . ILE A 1 163 ? 134.194 141.086 160.492 1.00 27.27 ? 163 ILE A CB  1 
ATOM   582  C CG1 . ILE A 1 163 ? 135.145 140.638 161.598 1.00 27.03 ? 163 ILE A CG1 1 
ATOM   583  C CG2 . ILE A 1 163 ? 132.766 140.889 160.957 1.00 25.19 ? 163 ILE A CG2 1 
ATOM   584  C CD1 . ILE A 1 163 ? 135.316 141.653 162.695 1.00 23.91 ? 163 ILE A CD1 1 
ATOM   585  N N   . MET A 1 164 ? 133.364 141.598 157.440 1.00 23.10 ? 164 MET A N   1 
ATOM   586  C CA  . MET A 1 164 ? 132.348 141.805 156.413 1.00 22.05 ? 164 MET A CA  1 
ATOM   587  C C   . MET A 1 164 ? 132.558 140.889 155.213 1.00 25.06 ? 164 MET A C   1 
ATOM   588  O O   . MET A 1 164 ? 131.585 140.537 154.537 1.00 26.77 ? 164 MET A O   1 
ATOM   589  C CB  . MET A 1 164 ? 132.332 143.267 155.975 1.00 30.98 ? 164 MET A CB  1 
ATOM   590  C CG  . MET A 1 164 ? 131.790 144.215 157.027 1.00 30.51 ? 164 MET A CG  1 
ATOM   591  S SD  . MET A 1 164 ? 129.993 144.299 157.022 1.00 47.95 ? 164 MET A SD  1 
ATOM   592  C CE  . MET A 1 164 ? 129.694 145.197 158.540 1.00 25.32 ? 164 MET A CE  1 
ATOM   593  N N   . HIS A 1 165 ? 133.805 140.476 154.951 1.00 32.74 ? 165 HIS A N   1 
ATOM   594  C CA  . HIS A 1 165 ? 134.066 139.449 153.947 1.00 31.74 ? 165 HIS A CA  1 
ATOM   595  C C   . HIS A 1 165 ? 133.399 138.133 154.320 1.00 30.59 ? 165 HIS A C   1 
ATOM   596  O O   . HIS A 1 165 ? 132.742 137.501 153.484 1.00 34.89 ? 165 HIS A O   1 
ATOM   597  C CB  . HIS A 1 165 ? 135.573 139.242 153.794 1.00 33.06 ? 165 HIS A CB  1 
ATOM   598  C CG  . HIS A 1 165 ? 136.226 140.158 152.808 1.00 35.62 ? 165 HIS A CG  1 
ATOM   599  N ND1 . HIS A 1 165 ? 136.466 141.489 153.071 1.00 40.17 ? 165 HIS A ND1 1 
ATOM   600  C CD2 . HIS A 1 165 ? 136.724 139.925 151.572 1.00 34.65 ? 165 HIS A CD2 1 
ATOM   601  C CE1 . HIS A 1 165 ? 137.065 142.041 152.032 1.00 35.14 ? 165 HIS A CE1 1 
ATOM   602  N NE2 . HIS A 1 165 ? 137.231 141.113 151.107 1.00 39.22 ? 165 HIS A NE2 1 
ATOM   603  N N   . LEU A 1 166 ? 133.545 137.715 155.582 1.00 30.57 ? 166 LEU A N   1 
ATOM   604  C CA  . LEU A 1 166 ? 132.922 136.466 156.021 1.00 28.42 ? 166 LEU A CA  1 
ATOM   605  C C   . LEU A 1 166 ? 131.399 136.573 156.045 1.00 29.15 ? 166 LEU A C   1 
ATOM   606  O O   . LEU A 1 166 ? 130.697 135.606 155.718 1.00 25.41 ? 166 LEU A O   1 
ATOM   607  C CB  . LEU A 1 166 ? 133.454 136.056 157.393 1.00 28.26 ? 166 LEU A CB  1 
ATOM   608  C CG  . LEU A 1 166 ? 134.972 135.952 157.535 1.00 25.56 ? 166 LEU A CG  1 
ATOM   609  C CD1 . LEU A 1 166 ? 135.378 135.465 158.909 1.00 27.99 ? 166 LEU A CD1 1 
ATOM   610  C CD2 . LEU A 1 166 ? 135.557 135.072 156.460 1.00 24.23 ? 166 LEU A CD2 1 
ATOM   611  N N   . CYS A 1 167 ? 130.874 137.747 156.409 1.00 29.14 ? 167 CYS A N   1 
ATOM   612  C CA  . CYS A 1 167 ? 129.427 137.966 156.401 1.00 20.99 ? 167 CYS A CA  1 
ATOM   613  C C   . CYS A 1 167 ? 128.855 137.904 154.987 1.00 23.61 ? 167 CYS A C   1 
ATOM   614  O O   . CYS A 1 167 ? 127.808 137.284 154.755 1.00 25.98 ? 167 CYS A O   1 
ATOM   615  C CB  . CYS A 1 167 ? 129.105 139.310 157.053 1.00 23.24 ? 167 CYS A CB  1 
ATOM   616  S SG  . CYS A 1 167 ? 127.367 139.762 157.025 1.00 31.21 ? 167 CYS A SG  1 
ATOM   617  N N   . ALA A 1 168 ? 129.542 138.527 154.024 1.00 23.69 ? 168 ALA A N   1 
ATOM   618  C CA  . ALA A 1 168 ? 129.081 138.498 152.641 1.00 16.21 ? 168 ALA A CA  1 
ATOM   619  C C   . ALA A 1 168 ? 129.208 137.105 152.042 1.00 20.65 ? 168 ALA A C   1 
ATOM   620  O O   . ALA A 1 168 ? 128.370 136.697 151.231 1.00 25.61 ? 168 ALA A O   1 
ATOM   621  C CB  . ALA A 1 168 ? 129.859 139.515 151.810 1.00 24.18 ? 168 ALA A CB  1 
ATOM   622  N N   . ILE A 1 169 ? 130.245 136.358 152.437 1.00 27.62 ? 169 ILE A N   1 
ATOM   623  C CA  . ILE A 1 169 ? 130.402 134.979 151.980 1.00 22.74 ? 169 ILE A CA  1 
ATOM   624  C C   . ILE A 1 169 ? 129.273 134.104 152.513 1.00 23.01 ? 169 ILE A C   1 
ATOM   625  O O   . ILE A 1 169 ? 128.709 133.285 151.776 1.00 28.05 ? 169 ILE A O   1 
ATOM   626  C CB  . ILE A 1 169 ? 131.795 134.451 152.377 1.00 19.78 ? 169 ILE A CB  1 
ATOM   627  C CG1 . ILE A 1 169 ? 132.837 134.928 151.369 1.00 23.62 ? 169 ILE A CG1 1 
ATOM   628  C CG2 . ILE A 1 169 ? 131.834 132.937 152.469 1.00 20.76 ? 169 ILE A CG2 1 
ATOM   629  C CD1 . ILE A 1 169 ? 134.243 134.574 151.740 1.00 20.40 ? 169 ILE A CD1 1 
ATOM   630  N N   . SER A 1 170 ? 128.896 134.293 153.784 1.00 23.88 ? 170 SER A N   1 
ATOM   631  C CA  . SER A 1 170 ? 127.779 133.542 154.359 1.00 18.59 ? 170 SER A CA  1 
ATOM   632  C C   . SER A 1 170 ? 126.452 133.880 153.684 1.00 21.38 ? 170 SER A C   1 
ATOM   633  O O   . SER A 1 170 ? 125.644 132.983 153.410 1.00 29.92 ? 170 SER A O   1 
ATOM   634  C CB  . SER A 1 170 ? 127.690 133.807 155.859 1.00 22.93 ? 170 SER A CB  1 
ATOM   635  O OG  . SER A 1 170 ? 126.720 132.973 156.463 1.00 32.28 ? 170 SER A OG  1 
ATOM   636  N N   . LEU A 1 171 ? 126.217 135.166 153.399 1.00 24.63 ? 171 LEU A N   1 
ATOM   637  C CA  . LEU A 1 171 ? 124.994 135.565 152.702 1.00 23.13 ? 171 LEU A CA  1 
ATOM   638  C C   . LEU A 1 171 ? 124.947 135.014 151.279 1.00 30.62 ? 171 LEU A C   1 
ATOM   639  O O   . LEU A 1 171 ? 123.892 134.553 150.821 1.00 36.14 ? 171 LEU A O   1 
ATOM   640  C CB  . LEU A 1 171 ? 124.872 137.086 152.685 1.00 22.67 ? 171 LEU A CB  1 
ATOM   641  C CG  . LEU A 1 171 ? 124.241 137.731 153.915 1.00 27.68 ? 171 LEU A CG  1 
ATOM   642  C CD1 . LEU A 1 171 ? 124.808 139.118 154.126 1.00 23.84 ? 171 LEU A CD1 1 
ATOM   643  C CD2 . LEU A 1 171 ? 122.735 137.789 153.752 1.00 29.97 ? 171 LEU A CD2 1 
ATOM   644  N N   . ASP A 1 172 ? 126.091 135.048 150.592 1.00 24.79 ? 172 ASP A N   1 
ATOM   645  C CA  . ASP A 1 172 ? 126.148 134.525 149.199 1.00 16.94 ? 172 ASP A CA  1 
ATOM   646  C C   . ASP A 1 172 ? 125.904 133.012 149.230 1.00 27.51 ? 172 ASP A C   1 
ATOM   647  O O   . ASP A 1 172 ? 125.162 132.518 148.354 1.00 26.91 ? 172 ASP A O   1 
ATOM   648  C CB  . ASP A 1 172 ? 127.444 134.921 148.509 1.00 22.03 ? 172 ASP A CB  1 
ATOM   649  C CG  . ASP A 1 172 ? 127.350 135.079 146.999 1.00 33.03 ? 172 ASP A CG  1 
ATOM   650  O OD1 . ASP A 1 172 ? 126.243 134.879 146.455 1.00 34.17 ? 172 ASP A OD1 1 
ATOM   651  O OD2 . ASP A 1 172 ? 128.386 135.397 146.378 1.00 41.51 ? 172 ASP A OD2 1 
ATOM   652  N N   . ARG A 1 173 ? 126.491 132.309 150.205 1.00 28.67 ? 173 ARG A N   1 
ATOM   653  C CA  . ARG A 1 173 ? 126.267 130.871 150.324 1.00 15.43 ? 173 ARG A CA  1 
ATOM   654  C C   . ARG A 1 173 ? 124.808 130.548 150.609 1.00 18.58 ? 173 ARG A C   1 
ATOM   655  O O   . ARG A 1 173 ? 124.281 129.568 150.073 1.00 32.67 ? 173 ARG A O   1 
ATOM   656  C CB  . ARG A 1 173 ? 127.153 130.276 151.414 1.00 14.90 ? 173 ARG A CB  1 
ATOM   657  C CG  . ARG A 1 173 ? 128.582 130.032 150.989 1.00 20.71 ? 173 ARG A CG  1 
ATOM   658  C CD  . ARG A 1 173 ? 129.410 129.504 152.146 1.00 26.77 ? 173 ARG A CD  1 
ATOM   659  N NE  . ARG A 1 173 ? 130.821 129.391 151.799 1.00 31.19 ? 173 ARG A NE  1 
ATOM   660  C CZ  . ARG A 1 173 ? 131.774 129.029 152.646 1.00 26.99 ? 173 ARG A CZ  1 
ATOM   661  N NH1 . ARG A 1 173 ? 131.506 128.748 153.909 1.00 25.13 ? 173 ARG A NH1 1 
ATOM   662  N NH2 . ARG A 1 173 ? 133.029 128.948 152.214 1.00 20.98 ? 173 ARG A NH2 1 
ATOM   663  N N   . TYR A 1 174 ? 124.141 131.356 151.439 1.00 14.56 ? 174 TYR A N   1 
ATOM   664  C CA  . TYR A 1 174 ? 122.718 131.139 151.690 1.00 13.29 ? 174 TYR A CA  1 
ATOM   665  C C   . TYR A 1 174 ? 121.887 131.349 150.428 1.00 20.93 ? 174 TYR A C   1 
ATOM   666  O O   . TYR A 1 174 ? 120.957 130.581 150.158 1.00 26.31 ? 174 TYR A O   1 
ATOM   667  C CB  . TYR A 1 174 ? 122.221 132.056 152.804 1.00 15.96 ? 174 TYR A CB  1 
ATOM   668  C CG  . TYR A 1 174 ? 120.715 132.089 152.899 1.00 15.34 ? 174 TYR A CG  1 
ATOM   669  C CD1 . TYR A 1 174 ? 119.996 130.950 153.233 1.00 20.44 ? 174 TYR A CD1 1 
ATOM   670  C CD2 . TYR A 1 174 ? 120.011 133.253 152.634 1.00 20.72 ? 174 TYR A CD2 1 
ATOM   671  C CE1 . TYR A 1 174 ? 118.623 130.972 153.308 1.00 22.01 ? 174 TYR A CE1 1 
ATOM   672  C CE2 . TYR A 1 174 ? 118.636 133.285 152.709 1.00 23.55 ? 174 TYR A CE2 1 
ATOM   673  C CZ  . TYR A 1 174 ? 117.949 132.142 153.047 1.00 24.91 ? 174 TYR A CZ  1 
ATOM   674  O OH  . TYR A 1 174 ? 116.578 132.170 153.123 1.00 30.59 ? 174 TYR A OH  1 
ATOM   675  N N   . VAL A 1 175 ? 122.209 132.381 149.642 1.00 28.36 ? 175 VAL A N   1 
ATOM   676  C CA  . VAL A 1 175 ? 121.467 132.613 148.401 1.00 26.38 ? 175 VAL A CA  1 
ATOM   677  C C   . VAL A 1 175 ? 121.764 131.517 147.377 1.00 24.09 ? 175 VAL A C   1 
ATOM   678  O O   . VAL A 1 175 ? 120.857 131.023 146.698 1.00 20.65 ? 175 VAL A O   1 
ATOM   679  C CB  . VAL A 1 175 ? 121.766 134.021 147.851 1.00 23.99 ? 175 VAL A CB  1 
ATOM   680  C CG1 . VAL A 1 175 ? 121.037 134.261 146.543 1.00 23.22 ? 175 VAL A CG1 1 
ATOM   681  C CG2 . VAL A 1 175 ? 121.333 135.071 148.850 1.00 26.54 ? 175 VAL A CG2 1 
ATOM   682  N N   . ALA A 1 176 ? 123.015 131.079 147.287 1.00 25.80 ? 176 ALA A N   1 
ATOM   683  C CA  . ALA A 1 176 ? 123.397 130.034 146.340 1.00 21.59 ? 176 ALA A CA  1 
ATOM   684  C C   . ALA A 1 176 ? 123.016 128.653 146.790 1.00 20.26 ? 176 ALA A C   1 
ATOM   685  O O   . ALA A 1 176 ? 123.193 127.726 145.999 1.00 29.60 ? 176 ALA A O   1 
ATOM   686  C CB  . ALA A 1 176 ? 124.903 130.086 146.083 1.00 25.77 ? 176 ALA A CB  1 
ATOM   687  N N   . ILE A 1 177 ? 122.531 128.456 148.012 1.00 22.11 ? 177 ILE A N   1 
ATOM   688  C CA  . ILE A 1 177 ? 122.130 127.130 148.462 1.00 19.07 ? 177 ILE A CA  1 
ATOM   689  C C   . ILE A 1 177 ? 120.606 127.041 148.532 1.00 23.74 ? 177 ILE A C   1 
ATOM   690  O O   . ILE A 1 177 ? 120.019 126.009 148.181 1.00 22.87 ? 177 ILE A O   1 
ATOM   691  C CB  . ILE A 1 177 ? 122.823 126.812 149.803 1.00 11.18 ? 177 ILE A CB  1 
ATOM   692  C CG1 . ILE A 1 177 ? 124.216 126.241 149.533 1.00 4.21  ? 177 ILE A CG1 1 
ATOM   693  C CG2 . ILE A 1 177 ? 122.019 125.865 150.674 1.00 20.16 ? 177 ILE A CG2 1 
ATOM   694  C CD1 . ILE A 1 177 ? 125.008 125.936 150.775 1.00 18.02 ? 177 ILE A CD1 1 
ATOM   695  N N   . GLN A 1 178 ? 119.951 128.137 148.935 1.00 22.88 ? 178 GLN A N   1 
ATOM   696  C CA  . GLN A 1 178 ? 118.492 128.140 149.050 1.00 23.15 ? 178 GLN A CA  1 
ATOM   697  C C   . GLN A 1 178 ? 117.803 128.031 147.692 1.00 29.71 ? 178 GLN A C   1 
ATOM   698  O O   . GLN A 1 178 ? 116.931 127.177 147.503 1.00 32.24 ? 178 GLN A O   1 
ATOM   699  C CB  . GLN A 1 178 ? 118.030 129.402 149.777 1.00 28.35 ? 178 GLN A CB  1 
ATOM   700  C CG  . GLN A 1 178 ? 116.530 129.651 149.711 1.00 27.61 ? 178 GLN A CG  1 
ATOM   701  C CD  . GLN A 1 178 ? 115.720 128.636 150.494 1.00 38.42 ? 178 GLN A CD  1 
ATOM   702  O OE1 . GLN A 1 178 ? 116.207 128.039 151.454 1.00 40.41 ? 178 GLN A OE1 1 
ATOM   703  N NE2 . GLN A 1 178 ? 114.473 128.437 150.087 1.00 39.11 ? 178 GLN A NE2 1 
ATOM   704  N N   . ASN A 1 179 ? 118.176 128.879 146.736 1.00 34.70 ? 179 ASN A N   1 
ATOM   705  C CA  . ASN A 1 179 ? 117.615 128.841 145.383 1.00 32.57 ? 179 ASN A CA  1 
ATOM   706  C C   . ASN A 1 179 ? 118.733 128.872 144.350 1.00 31.00 ? 179 ASN A C   1 
ATOM   707  O O   . ASN A 1 179 ? 119.132 129.936 143.865 1.00 34.08 ? 179 ASN A O   1 
ATOM   708  C CB  . ASN A 1 179 ? 116.595 129.967 145.180 1.00 30.19 ? 179 ASN A CB  1 
ATOM   709  C CG  . ASN A 1 179 ? 117.010 131.279 145.829 1.00 37.18 ? 179 ASN A CG  1 
ATOM   710  O OD1 . ASN A 1 179 ? 118.179 131.644 145.862 1.00 38.98 ? 179 ASN A OD1 1 
ATOM   711  N ND2 . ASN A 1 179 ? 116.028 131.996 146.361 1.00 38.90 ? 179 ASN A ND2 1 
ATOM   712  N N   . PRO A 1 180 ? 119.257 127.700 143.974 1.00 25.28 ? 180 PRO A N   1 
ATOM   713  C CA  . PRO A 1 180 ? 120.452 127.667 143.118 1.00 25.39 ? 180 PRO A CA  1 
ATOM   714  C C   . PRO A 1 180 ? 120.211 128.100 141.684 1.00 29.16 ? 180 PRO A C   1 
ATOM   715  O O   . PRO A 1 180 ? 121.169 128.480 141.000 1.00 36.82 ? 180 PRO A O   1 
ATOM   716  C CB  . PRO A 1 180 ? 120.882 126.195 143.187 1.00 27.26 ? 180 PRO A CB  1 
ATOM   717  C CG  . PRO A 1 180 ? 120.186 125.637 144.379 1.00 25.76 ? 180 PRO A CG  1 
ATOM   718  C CD  . PRO A 1 180 ? 118.884 126.353 144.427 1.00 26.49 ? 180 PRO A CD  1 
ATOM   719  N N   . ILE A 1 181 ? 118.973 128.042 141.195 1.00 27.74 ? 181 ILE A N   1 
ATOM   720  C CA  . ILE A 1 181 ? 118.700 128.455 139.821 1.00 21.08 ? 181 ILE A CA  1 
ATOM   721  C C   . ILE A 1 181 ? 118.778 129.972 139.698 1.00 32.66 ? 181 ILE A C   1 
ATOM   722  O O   . ILE A 1 181 ? 119.463 130.506 138.818 1.00 42.81 ? 181 ILE A O   1 
ATOM   723  C CB  . ILE A 1 181 ? 117.334 127.922 139.356 1.00 24.42 ? 181 ILE A CB  1 
ATOM   724  C CG1 . ILE A 1 181 ? 117.369 126.403 139.225 1.00 33.11 ? 181 ILE A CG1 1 
ATOM   725  C CG2 . ILE A 1 181 ? 116.945 128.529 138.029 1.00 30.05 ? 181 ILE A CG2 1 
ATOM   726  C CD1 . ILE A 1 181 ? 116.009 125.786 139.034 1.00 32.99 ? 181 ILE A CD1 1 
ATOM   727  N N   . HIS A 1 182 ? 118.101 130.688 140.599 1.00 42.21 ? 182 HIS A N   1 
ATOM   728  C CA  . HIS A 1 182 ? 118.043 132.144 140.508 1.00 37.97 ? 182 HIS A CA  1 
ATOM   729  C C   . HIS A 1 182 ? 119.341 132.808 140.942 1.00 31.46 ? 182 HIS A C   1 
ATOM   730  O O   . HIS A 1 182 ? 119.569 133.971 140.601 1.00 41.56 ? 182 HIS A O   1 
ATOM   731  C CB  . HIS A 1 182 ? 116.878 132.680 141.340 1.00 35.95 ? 182 HIS A CB  1 
ATOM   732  C CG  . HIS A 1 182 ? 115.577 131.993 141.065 1.00 46.73 ? 182 HIS A CG  1 
ATOM   733  N ND1 . HIS A 1 182 ? 115.057 131.023 141.895 1.00 48.04 ? 182 HIS A ND1 1 
ATOM   734  C CD2 . HIS A 1 182 ? 114.696 132.126 140.046 1.00 44.56 ? 182 HIS A CD2 1 
ATOM   735  C CE1 . HIS A 1 182 ? 113.909 130.593 141.403 1.00 41.76 ? 182 HIS A CE1 1 
ATOM   736  N NE2 . HIS A 1 182 ? 113.667 131.246 140.281 1.00 44.94 ? 182 HIS A NE2 1 
ATOM   737  N N   . HIS A 1 183 ? 120.188 132.107 141.695 1.00 26.99 ? 183 HIS A N   1 
ATOM   738  C CA  . HIS A 1 183 ? 121.517 132.627 141.988 1.00 26.21 ? 183 HIS A CA  1 
ATOM   739  C C   . HIS A 1 183 ? 122.411 132.552 140.759 1.00 29.88 ? 183 HIS A C   1 
ATOM   740  O O   . HIS A 1 183 ? 123.108 133.514 140.424 1.00 38.19 ? 183 HIS A O   1 
ATOM   741  C CB  . HIS A 1 183 ? 122.139 131.859 143.153 1.00 28.24 ? 183 HIS A CB  1 
ATOM   742  C CG  . HIS A 1 183 ? 123.551 132.254 143.452 1.00 31.37 ? 183 HIS A CG  1 
ATOM   743  N ND1 . HIS A 1 183 ? 124.636 131.630 142.878 1.00 36.01 ? 183 HIS A ND1 1 
ATOM   744  C CD2 . HIS A 1 183 ? 124.055 133.209 144.268 1.00 32.80 ? 183 HIS A CD2 1 
ATOM   745  C CE1 . HIS A 1 183 ? 125.749 132.184 143.325 1.00 33.34 ? 183 HIS A CE1 1 
ATOM   746  N NE2 . HIS A 1 183 ? 125.424 133.143 144.172 1.00 33.48 ? 183 HIS A NE2 1 
ATOM   747  N N   . SER A 1 184 ? 122.392 131.411 140.062 1.00 37.08 ? 184 SER A N   1 
ATOM   748  C CA  . SER A 1 184 ? 123.240 131.242 138.886 1.00 40.23 ? 184 SER A CA  1 
ATOM   749  C C   . SER A 1 184 ? 122.718 132.033 137.695 1.00 40.99 ? 184 SER A C   1 
ATOM   750  O O   . SER A 1 184 ? 123.462 132.279 136.740 1.00 42.34 ? 184 SER A O   1 
ATOM   751  C CB  . SER A 1 184 ? 123.355 129.761 138.530 1.00 39.68 ? 184 SER A CB  1 
ATOM   752  O OG  . SER A 1 184 ? 123.822 129.008 139.634 1.00 44.65 ? 184 SER A OG  1 
ATOM   753  N N   . ARG A 1 185 ? 121.441 132.422 137.726 1.00 44.59 ? 185 ARG A N   1 
ATOM   754  C CA  . ARG A 1 185 ? 120.900 133.298 136.693 1.00 43.88 ? 185 ARG A CA  1 
ATOM   755  C C   . ARG A 1 185 ? 121.506 134.695 136.779 1.00 45.02 ? 185 ARG A C   1 
ATOM   756  O O   . ARG A 1 185 ? 121.778 135.320 135.748 1.00 49.91 ? 185 ARG A O   1 
ATOM   757  C CB  . ARG A 1 185 ? 119.375 133.338 136.815 1.00 41.19 ? 185 ARG A CB  1 
ATOM   758  C CG  . ARG A 1 185 ? 118.668 134.408 136.007 1.00 41.22 ? 185 ARG A CG  1 
ATOM   759  C CD  . ARG A 1 185 ? 117.162 134.182 135.989 1.00 44.50 ? 185 ARG A CD  1 
ATOM   760  N NE  . ARG A 1 185 ? 116.814 132.777 136.169 1.00 44.45 ? 185 ARG A NE  1 
ATOM   761  C CZ  . ARG A 1 185 ? 116.464 131.960 135.184 1.00 47.66 ? 185 ARG A CZ  1 
ATOM   762  N NH1 . ARG A 1 185 ? 116.394 132.378 133.932 1.00 51.72 ? 185 ARG A NH1 1 
ATOM   763  N NH2 . ARG A 1 185 ? 116.180 130.692 135.463 1.00 42.00 ? 185 ARG A NH2 1 
ATOM   764  N N   . PHE A 1 186 ? 121.760 135.183 137.993 1.00 47.46 ? 186 PHE A N   1 
ATOM   765  C CA  . PHE A 1 186 ? 122.319 136.513 138.207 1.00 48.18 ? 186 PHE A CA  1 
ATOM   766  C C   . PHE A 1 186 ? 123.807 136.511 138.531 1.00 48.36 ? 186 PHE A C   1 
ATOM   767  O O   . PHE A 1 186 ? 124.342 137.565 138.892 1.00 46.17 ? 186 PHE A O   1 
ATOM   768  C CB  . PHE A 1 186 ? 121.576 137.247 139.340 1.00 47.28 ? 186 PHE A CB  1 
ATOM   769  C CG  . PHE A 1 186 ? 120.219 137.818 138.959 1.00 52.84 ? 186 PHE A CG  1 
ATOM   770  C CD1 . PHE A 1 186 ? 119.501 137.368 137.857 1.00 49.35 ? 186 PHE A CD1 1 
ATOM   771  C CD2 . PHE A 1 186 ? 119.663 138.822 139.737 1.00 52.06 ? 186 PHE A CD2 1 
ATOM   772  C CE1 . PHE A 1 186 ? 118.266 137.908 137.541 1.00 49.40 ? 186 PHE A CE1 1 
ATOM   773  C CE2 . PHE A 1 186 ? 118.429 139.368 139.426 1.00 51.50 ? 186 PHE A CE2 1 
ATOM   774  C CZ  . PHE A 1 186 ? 117.731 138.910 138.327 1.00 52.76 ? 186 PHE A CZ  1 
ATOM   775  N N   . ASN A 1 187 ? 124.495 135.375 138.415 1.00 54.58 ? 187 ASN A N   1 
ATOM   776  C CA  . ASN A 1 187 ? 125.873 135.254 138.897 1.00 54.16 ? 187 ASN A CA  1 
ATOM   777  C C   . ASN A 1 187 ? 126.914 135.743 137.899 1.00 51.60 ? 187 ASN A C   1 
ATOM   778  O O   . ASN A 1 187 ? 127.663 134.942 137.336 1.00 53.05 ? 187 ASN A O   1 
ATOM   779  C CB  . ASN A 1 187 ? 126.148 133.803 139.287 1.00 52.84 ? 187 ASN A CB  1 
ATOM   780  N N   . SER A 1 188 ? 126.989 137.050 137.668 1.00 49.71 ? 188 SER A N   1 
ATOM   781  C CA  . SER A 1 188 ? 128.037 137.590 136.818 1.00 52.53 ? 188 SER A CA  1 
ATOM   782  C C   . SER A 1 188 ? 129.294 137.875 137.638 1.00 52.41 ? 188 SER A C   1 
ATOM   783  O O   . SER A 1 188 ? 129.375 137.574 138.831 1.00 51.21 ? 188 SER A O   1 
ATOM   784  C CB  . SER A 1 188 ? 127.558 138.865 136.124 1.00 49.61 ? 188 SER A CB  1 
ATOM   785  N N   . ARG A 1 189 ? 130.298 138.451 136.971 1.00 53.37 ? 189 ARG A N   1 
ATOM   786  C CA  . ARG A 1 189 ? 131.450 138.990 137.686 1.00 53.09 ? 189 ARG A CA  1 
ATOM   787  C C   . ARG A 1 189 ? 131.130 140.335 138.323 1.00 58.98 ? 189 ARG A C   1 
ATOM   788  O O   . ARG A 1 189 ? 131.864 140.786 139.215 1.00 61.45 ? 189 ARG A O   1 
ATOM   789  C CB  . ARG A 1 189 ? 132.643 139.120 136.741 1.00 52.08 ? 189 ARG A CB  1 
ATOM   790  N N   . THR A 1 190 ? 130.040 140.976 137.885 1.00 61.58 ? 190 THR A N   1 
ATOM   791  C CA  . THR A 1 190 ? 129.550 142.180 138.546 1.00 62.15 ? 190 THR A CA  1 
ATOM   792  C C   . THR A 1 190 ? 129.106 141.891 139.972 1.00 62.40 ? 190 THR A C   1 
ATOM   793  O O   . THR A 1 190 ? 129.187 142.775 140.829 1.00 62.22 ? 190 THR A O   1 
ATOM   794  C CB  . THR A 1 190 ? 128.394 142.788 137.754 1.00 60.47 ? 190 THR A CB  1 
ATOM   795  O OG1 . THR A 1 190 ? 127.270 141.901 137.790 1.00 58.35 ? 190 THR A OG1 1 
ATOM   796  C CG2 . THR A 1 190 ? 128.804 143.011 136.309 1.00 61.65 ? 190 THR A CG2 1 
ATOM   797  N N   . LYS A 1 191 ? 128.646 140.663 140.238 1.00 52.93 ? 191 LYS A N   1 
ATOM   798  C CA  . LYS A 1 191 ? 128.357 140.211 141.596 1.00 50.28 ? 191 LYS A CA  1 
ATOM   799  C C   . LYS A 1 191 ? 129.590 140.309 142.487 1.00 49.32 ? 191 LYS A C   1 
ATOM   800  O O   . LYS A 1 191 ? 129.543 140.896 143.573 1.00 51.93 ? 191 LYS A O   1 
ATOM   801  C CB  . LYS A 1 191 ? 127.846 138.769 141.556 1.00 55.69 ? 191 LYS A CB  1 
ATOM   802  C CG  . LYS A 1 191 ? 127.543 138.156 142.914 1.00 53.86 ? 191 LYS A CG  1 
ATOM   803  C CD  . LYS A 1 191 ? 126.096 138.374 143.314 1.00 55.66 ? 191 LYS A CD  1 
ATOM   804  C CE  . LYS A 1 191 ? 125.173 137.464 142.522 1.00 53.17 ? 191 LYS A CE  1 
ATOM   805  N NZ  . LYS A 1 191 ? 123.761 137.564 142.975 1.00 53.02 ? 191 LYS A NZ  1 
ATOM   806  N N   . ALA A 1 192 ? 130.716 139.763 142.016 1.00 50.70 ? 192 ALA A N   1 
ATOM   807  C CA  . ALA A 1 192 ? 131.948 139.779 142.800 1.00 50.30 ? 192 ALA A CA  1 
ATOM   808  C C   . ALA A 1 192 ? 132.494 141.189 142.957 1.00 51.10 ? 192 ALA A C   1 
ATOM   809  O O   . ALA A 1 192 ? 132.953 141.563 144.044 1.00 60.54 ? 192 ALA A O   1 
ATOM   810  C CB  . ALA A 1 192 ? 133.000 138.884 142.153 1.00 53.60 ? 192 ALA A CB  1 
ATOM   811  N N   . PHE A 1 193 ? 132.444 141.990 141.888 1.00 53.87 ? 193 PHE A N   1 
ATOM   812  C CA  . PHE A 1 193 ? 132.984 143.344 141.976 1.00 60.26 ? 193 PHE A CA  1 
ATOM   813  C C   . PHE A 1 193 ? 132.119 144.239 142.862 1.00 58.08 ? 193 PHE A C   1 
ATOM   814  O O   . PHE A 1 193 ? 132.650 145.041 143.640 1.00 53.96 ? 193 PHE A O   1 
ATOM   815  C CB  . PHE A 1 193 ? 133.153 143.937 140.579 1.00 59.87 ? 193 PHE A CB  1 
ATOM   816  C CG  . PHE A 1 193 ? 134.271 143.308 139.793 1.00 60.32 ? 193 PHE A CG  1 
ATOM   817  C CD1 . PHE A 1 193 ? 135.503 143.080 140.387 1.00 58.63 ? 193 PHE A CD1 1 
ATOM   818  C CD2 . PHE A 1 193 ? 134.097 142.956 138.464 1.00 59.68 ? 193 PHE A CD2 1 
ATOM   819  C CE1 . PHE A 1 193 ? 136.538 142.502 139.673 1.00 57.46 ? 193 PHE A CE1 1 
ATOM   820  C CE2 . PHE A 1 193 ? 135.132 142.378 137.743 1.00 60.17 ? 193 PHE A CE2 1 
ATOM   821  C CZ  . PHE A 1 193 ? 136.352 142.153 138.350 1.00 57.78 ? 193 PHE A CZ  1 
ATOM   822  N N   . LEU A 1 194 ? 130.794 144.079 142.805 1.00 50.48 ? 194 LEU A N   1 
ATOM   823  C CA  . LEU A 1 194 ? 129.918 144.840 143.688 1.00 52.67 ? 194 LEU A CA  1 
ATOM   824  C C   . LEU A 1 194 ? 130.041 144.375 145.134 1.00 54.28 ? 194 LEU A C   1 
ATOM   825  O O   . LEU A 1 194 ? 129.942 145.191 146.053 1.00 50.46 ? 194 LEU A O   1 
ATOM   826  C CB  . LEU A 1 194 ? 128.468 144.739 143.212 1.00 52.61 ? 194 LEU A CB  1 
ATOM   827  C CG  . LEU A 1 194 ? 127.910 145.925 142.419 1.00 54.06 ? 194 LEU A CG  1 
ATOM   828  C CD1 . LEU A 1 194 ? 128.631 146.098 141.091 1.00 52.02 ? 194 LEU A CD1 1 
ATOM   829  C CD2 . LEU A 1 194 ? 126.414 145.772 142.203 1.00 51.20 ? 194 LEU A CD2 1 
ATOM   830  N N   . LYS A 1 195 ? 130.275 143.076 145.357 1.00 54.78 ? 195 LYS A N   1 
ATOM   831  C CA  . LYS A 1 195 ? 130.471 142.577 146.716 1.00 47.73 ? 195 LYS A CA  1 
ATOM   832  C C   . LYS A 1 195 ? 131.762 143.114 147.323 1.00 43.76 ? 195 LYS A C   1 
ATOM   833  O O   . LYS A 1 195 ? 131.781 143.534 148.487 1.00 51.19 ? 195 LYS A O   1 
ATOM   834  C CB  . LYS A 1 195 ? 130.470 141.049 146.721 1.00 42.23 ? 195 LYS A CB  1 
ATOM   835  N N   . ILE A 1 196 ? 132.847 143.121 146.538 1.00 34.83 ? 196 ILE A N   1 
ATOM   836  C CA  . ILE A 1 196 ? 134.125 143.664 147.002 1.00 36.49 ? 196 ILE A CA  1 
ATOM   837  C C   . ILE A 1 196 ? 134.008 145.162 147.266 1.00 44.89 ? 196 ILE A C   1 
ATOM   838  O O   . ILE A 1 196 ? 134.495 145.667 148.291 1.00 50.27 ? 196 ILE A O   1 
ATOM   839  C CB  . ILE A 1 196 ? 135.236 143.345 145.983 1.00 38.25 ? 196 ILE A CB  1 
ATOM   840  C CG1 . ILE A 1 196 ? 135.585 141.860 146.025 1.00 44.58 ? 196 ILE A CG1 1 
ATOM   841  C CG2 . ILE A 1 196 ? 136.490 144.157 146.246 1.00 40.88 ? 196 ILE A CG2 1 
ATOM   842  C CD1 . ILE A 1 196 ? 136.500 141.426 144.906 1.00 47.42 ? 196 ILE A CD1 1 
ATOM   843  N N   . ILE A 1 197 ? 133.320 145.881 146.368 1.00 46.28 ? 197 ILE A N   1 
ATOM   844  C CA  . ILE A 1 197 ? 133.104 147.319 146.524 1.00 47.58 ? 197 ILE A CA  1 
ATOM   845  C C   . ILE A 1 197 ? 132.288 147.607 147.781 1.00 43.90 ? 197 ILE A C   1 
ATOM   846  O O   . ILE A 1 197 ? 132.621 148.508 148.558 1.00 42.85 ? 197 ILE A O   1 
ATOM   847  C CB  . ILE A 1 197 ? 132.440 147.892 145.255 1.00 46.24 ? 197 ILE A CB  1 
ATOM   848  C CG1 . ILE A 1 197 ? 133.502 148.208 144.198 1.00 46.84 ? 197 ILE A CG1 1 
ATOM   849  C CG2 . ILE A 1 197 ? 131.592 149.130 145.546 1.00 44.31 ? 197 ILE A CG2 1 
ATOM   850  C CD1 . ILE A 1 197 ? 134.395 149.373 144.554 1.00 45.26 ? 197 ILE A CD1 1 
ATOM   851  N N   . ALA A 1 198 ? 131.250 146.800 148.029 1.00 40.58 ? 198 ALA A N   1 
ATOM   852  C CA  . ALA A 1 198 ? 130.391 147.004 149.191 1.00 43.70 ? 198 ALA A CA  1 
ATOM   853  C C   . ALA A 1 198 ? 131.133 146.743 150.497 1.00 41.86 ? 198 ALA A C   1 
ATOM   854  O O   . ALA A 1 198 ? 131.046 147.545 151.435 1.00 40.92 ? 198 ALA A O   1 
ATOM   855  C CB  . ALA A 1 198 ? 129.155 146.110 149.090 1.00 44.43 ? 198 ALA A CB  1 
ATOM   856  N N   . VAL A 1 199 ? 131.889 145.640 150.571 1.00 38.99 ? 199 VAL A N   1 
ATOM   857  C CA  . VAL A 1 199 ? 132.562 145.326 151.831 1.00 33.13 ? 199 VAL A CA  1 
ATOM   858  C C   . VAL A 1 199 ? 133.716 146.292 152.102 1.00 36.81 ? 199 VAL A C   1 
ATOM   859  O O   . VAL A 1 199 ? 133.929 146.691 153.253 1.00 43.23 ? 199 VAL A O   1 
ATOM   860  C CB  . VAL A 1 199 ? 133.004 143.845 151.890 1.00 30.68 ? 199 VAL A CB  1 
ATOM   861  C CG1 . VAL A 1 199 ? 131.798 142.935 151.759 1.00 34.41 ? 199 VAL A CG1 1 
ATOM   862  C CG2 . VAL A 1 199 ? 134.048 143.496 150.845 1.00 35.25 ? 199 VAL A CG2 1 
ATOM   863  N N   . TRP A 1 200 ? 134.430 146.750 151.065 1.00 33.42 ? 200 TRP A N   1 
ATOM   864  C CA  . TRP A 1 200 ? 135.509 147.697 151.320 1.00 34.19 ? 200 TRP A CA  1 
ATOM   865  C C   . TRP A 1 200 ? 134.993 149.109 151.572 1.00 37.81 ? 200 TRP A C   1 
ATOM   866  O O   . TRP A 1 200 ? 135.594 149.846 152.363 1.00 32.36 ? 200 TRP A O   1 
ATOM   867  C CB  . TRP A 1 200 ? 136.507 147.671 150.167 1.00 32.91 ? 200 TRP A CB  1 
ATOM   868  C CG  . TRP A 1 200 ? 137.455 146.527 150.283 1.00 35.56 ? 200 TRP A CG  1 
ATOM   869  C CD1 . TRP A 1 200 ? 137.442 145.377 149.555 1.00 37.10 ? 200 TRP A CD1 1 
ATOM   870  C CD2 . TRP A 1 200 ? 138.549 146.409 151.200 1.00 39.76 ? 200 TRP A CD2 1 
ATOM   871  N NE1 . TRP A 1 200 ? 138.466 144.552 149.953 1.00 36.66 ? 200 TRP A NE1 1 
ATOM   872  C CE2 . TRP A 1 200 ? 139.161 145.164 150.962 1.00 40.15 ? 200 TRP A CE2 1 
ATOM   873  C CE3 . TRP A 1 200 ? 139.075 147.238 152.195 1.00 33.23 ? 200 TRP A CE3 1 
ATOM   874  C CZ2 . TRP A 1 200 ? 140.270 144.729 151.680 1.00 36.91 ? 200 TRP A CZ2 1 
ATOM   875  C CZ3 . TRP A 1 200 ? 140.176 146.803 152.907 1.00 29.84 ? 200 TRP A CZ3 1 
ATOM   876  C CH2 . TRP A 1 200 ? 140.761 145.561 152.646 1.00 33.88 ? 200 TRP A CH2 1 
ATOM   877  N N   . THR A 1 201 ? 133.872 149.491 150.949 1.00 40.30 ? 201 THR A N   1 
ATOM   878  C CA  . THR A 1 201 ? 133.235 150.768 151.252 1.00 40.72 ? 201 THR A CA  1 
ATOM   879  C C   . THR A 1 201 ? 132.717 150.791 152.684 1.00 43.55 ? 201 THR A C   1 
ATOM   880  O O   . THR A 1 201 ? 132.872 151.791 153.395 1.00 45.66 ? 201 THR A O   1 
ATOM   881  C CB  . THR A 1 201 ? 132.101 151.023 150.255 1.00 43.64 ? 201 THR A CB  1 
ATOM   882  O OG1 . THR A 1 201 ? 132.636 151.064 148.927 1.00 50.95 ? 201 THR A OG1 1 
ATOM   883  C CG2 . THR A 1 201 ? 131.394 152.340 150.541 1.00 42.42 ? 201 THR A CG2 1 
ATOM   884  N N   . ILE A 1 202 ? 132.125 149.679 153.133 1.00 44.29 ? 202 ILE A N   1 
ATOM   885  C CA  . ILE A 1 202 ? 131.642 149.578 154.508 1.00 39.40 ? 202 ILE A CA  1 
ATOM   886  C C   . ILE A 1 202 ? 132.813 149.619 155.488 1.00 34.13 ? 202 ILE A C   1 
ATOM   887  O O   . ILE A 1 202 ? 132.764 150.315 156.510 1.00 34.10 ? 202 ILE A O   1 
ATOM   888  C CB  . ILE A 1 202 ? 130.786 148.306 154.669 1.00 42.27 ? 202 ILE A CB  1 
ATOM   889  C CG1 . ILE A 1 202 ? 129.359 148.571 154.175 1.00 40.51 ? 202 ILE A CG1 1 
ATOM   890  C CG2 . ILE A 1 202 ? 130.784 147.804 156.110 1.00 41.02 ? 202 ILE A CG2 1 
ATOM   891  C CD1 . ILE A 1 202 ? 128.333 147.527 154.581 1.00 38.79 ? 202 ILE A CD1 1 
ATOM   892  N N   . SER A 1 203 ? 133.901 148.912 155.164 1.00 34.70 ? 203 SER A N   1 
ATOM   893  C CA  . SER A 1 203 ? 135.069 148.883 156.040 1.00 34.71 ? 203 SER A CA  1 
ATOM   894  C C   . SER A 1 203 ? 135.759 150.240 156.123 1.00 38.81 ? 203 SER A C   1 
ATOM   895  O O   . SER A 1 203 ? 136.327 150.580 157.167 1.00 40.16 ? 203 SER A O   1 
ATOM   896  C CB  . SER A 1 203 ? 136.048 147.822 155.548 1.00 40.36 ? 203 SER A CB  1 
ATOM   897  O OG  . SER A 1 203 ? 135.348 146.660 155.145 1.00 38.71 ? 203 SER A OG  1 
ATOM   898  N N   . VAL A 1 204 ? 135.736 151.018 155.038 1.00 48.31 ? 204 VAL A N   1 
ATOM   899  C CA  . VAL A 1 204 ? 136.253 152.384 155.088 1.00 50.89 ? 204 VAL A CA  1 
ATOM   900  C C   . VAL A 1 204 ? 135.321 153.283 155.898 1.00 49.32 ? 204 VAL A C   1 
ATOM   901  O O   . VAL A 1 204 ? 135.768 154.057 156.754 1.00 42.36 ? 204 VAL A O   1 
ATOM   902  C CB  . VAL A 1 204 ? 136.477 152.918 153.660 1.00 47.27 ? 204 VAL A CB  1 
ATOM   903  C CG1 . VAL A 1 204 ? 136.606 154.432 153.643 1.00 47.57 ? 204 VAL A CG1 1 
ATOM   904  C CG2 . VAL A 1 204 ? 137.720 152.292 153.062 1.00 49.35 ? 204 VAL A CG2 1 
ATOM   905  N N   . GLY A 1 205 ? 134.009 153.167 155.668 1.00 49.83 ? 205 GLY A N   1 
ATOM   906  C CA  . GLY A 1 205 ? 133.071 154.111 156.258 1.00 47.54 ? 205 GLY A CA  1 
ATOM   907  C C   . GLY A 1 205 ? 132.862 153.916 157.748 1.00 50.13 ? 205 GLY A C   1 
ATOM   908  O O   . GLY A 1 205 ? 132.607 154.878 158.475 1.00 53.61 ? 205 GLY A O   1 
ATOM   909  N N   . ILE A 1 206 ? 132.942 152.669 158.221 1.00 47.88 ? 206 ILE A N   1 
ATOM   910  C CA  . ILE A 1 206 ? 132.831 152.413 159.657 1.00 45.58 ? 206 ILE A CA  1 
ATOM   911  C C   . ILE A 1 206 ? 134.068 152.931 160.383 1.00 46.49 ? 206 ILE A C   1 
ATOM   912  O O   . ILE A 1 206 ? 133.971 153.538 161.458 1.00 50.93 ? 206 ILE A O   1 
ATOM   913  C CB  . ILE A 1 206 ? 132.585 150.912 159.917 1.00 45.27 ? 206 ILE A CB  1 
ATOM   914  C CG1 . ILE A 1 206 ? 131.226 150.489 159.352 1.00 46.48 ? 206 ILE A CG1 1 
ATOM   915  C CG2 . ILE A 1 206 ? 132.654 150.576 161.395 1.00 43.93 ? 206 ILE A CG2 1 
ATOM   916  C CD1 . ILE A 1 206 ? 130.057 151.282 159.882 1.00 46.96 ? 206 ILE A CD1 1 
ATOM   917  N N   . SER A 1 207 ? 135.241 152.761 159.777 1.00 40.17 ? 207 SER A N   1 
ATOM   918  C CA  . SER A 1 207 ? 136.492 153.194 160.382 1.00 39.99 ? 207 SER A CA  1 
ATOM   919  C C   . SER A 1 207 ? 136.774 154.679 160.191 1.00 50.53 ? 207 SER A C   1 
ATOM   920  O O   . SER A 1 207 ? 137.851 155.132 160.591 1.00 57.09 ? 207 SER A O   1 
ATOM   921  C CB  . SER A 1 207 ? 137.651 152.387 159.805 1.00 39.26 ? 207 SER A CB  1 
ATOM   922  O OG  . SER A 1 207 ? 137.361 151.004 159.824 1.00 50.25 ? 207 SER A OG  1 
ATOM   923  N N   . MET A 1 208 ? 135.845 155.428 159.592 1.00 54.78 ? 208 MET A N   1 
ATOM   924  C CA  . MET A 1 208 ? 136.082 156.835 159.263 1.00 53.92 ? 208 MET A CA  1 
ATOM   925  C C   . MET A 1 208 ? 136.405 157.775 160.435 1.00 49.19 ? 208 MET A C   1 
ATOM   926  O O   . MET A 1 208 ? 137.251 158.662 160.228 1.00 50.06 ? 208 MET A O   1 
ATOM   927  C CB  . MET A 1 208 ? 134.886 157.376 158.459 1.00 48.66 ? 208 MET A CB  1 
ATOM   928  N N   . PRO A 1 209 ? 135.800 157.691 161.635 1.00 41.51 ? 209 PRO A N   1 
ATOM   929  C CA  . PRO A 1 209 ? 136.205 158.652 162.678 1.00 44.14 ? 209 PRO A CA  1 
ATOM   930  C C   . PRO A 1 209 ? 137.542 158.353 163.340 1.00 47.46 ? 209 PRO A C   1 
ATOM   931  O O   . PRO A 1 209 ? 137.932 159.093 164.251 1.00 52.43 ? 209 PRO A O   1 
ATOM   932  C CB  . PRO A 1 209 ? 135.058 158.570 163.694 1.00 48.22 ? 209 PRO A CB  1 
ATOM   933  C CG  . PRO A 1 209 ? 133.917 158.065 162.932 1.00 48.32 ? 209 PRO A CG  1 
ATOM   934  C CD  . PRO A 1 209 ? 134.528 157.052 162.028 1.00 43.94 ? 209 PRO A CD  1 
ATOM   935  N N   . ILE A 1 210 ? 138.255 157.299 162.934 1.00 48.41 ? 210 ILE A N   1 
ATOM   936  C CA  . ILE A 1 210 ? 139.541 156.987 163.570 1.00 46.94 ? 210 ILE A CA  1 
ATOM   937  C C   . ILE A 1 210 ? 140.653 157.966 163.205 1.00 47.96 ? 210 ILE A C   1 
ATOM   938  O O   . ILE A 1 210 ? 141.239 158.553 164.125 1.00 51.22 ? 210 ILE A O   1 
ATOM   939  C CB  . ILE A 1 210 ? 139.915 155.519 163.323 1.00 44.52 ? 210 ILE A CB  1 
ATOM   940  N N   . PRO A 1 211 ? 141.021 158.207 161.900 1.00 52.24 ? 211 PRO A N   1 
ATOM   941  C CA  . PRO A 1 211 ? 142.228 159.019 161.672 1.00 52.75 ? 211 PRO A CA  1 
ATOM   942  C C   . PRO A 1 211 ? 142.022 160.527 161.743 1.00 49.66 ? 211 PRO A C   1 
ATOM   943  O O   . PRO A 1 211 ? 142.971 161.255 162.049 1.00 50.02 ? 211 PRO A O   1 
ATOM   944  C CB  . PRO A 1 211 ? 142.672 158.595 160.269 1.00 55.31 ? 211 PRO A CB  1 
ATOM   945  C CG  . PRO A 1 211 ? 141.433 158.244 159.577 1.00 54.98 ? 211 PRO A CG  1 
ATOM   946  C CD  . PRO A 1 211 ? 140.417 157.822 160.603 1.00 51.02 ? 211 PRO A CD  1 
ATOM   947  N N   . VAL A 1 212 ? 140.815 161.014 161.446 1.00 55.25 ? 212 VAL A N   1 
ATOM   948  C CA  . VAL A 1 212 ? 140.574 162.455 161.469 1.00 57.72 ? 212 VAL A CA  1 
ATOM   949  C C   . VAL A 1 212 ? 140.526 162.983 162.897 1.00 59.62 ? 212 VAL A C   1 
ATOM   950  O O   . VAL A 1 212 ? 140.940 164.118 163.161 1.00 58.56 ? 212 VAL A O   1 
ATOM   951  C CB  . VAL A 1 212 ? 139.289 162.805 160.690 1.00 56.12 ? 212 VAL A CB  1 
ATOM   952  C CG1 . VAL A 1 212 ? 139.551 162.762 159.195 1.00 55.12 ? 212 VAL A CG1 1 
ATOM   953  C CG2 . VAL A 1 212 ? 138.154 161.859 161.054 1.00 52.91 ? 212 VAL A CG2 1 
ATOM   954  N N   . PHE A 1 213 ? 140.032 162.178 163.838 1.00 54.84 ? 213 PHE A N   1 
ATOM   955  C CA  . PHE A 1 213 ? 139.861 162.598 165.220 1.00 53.84 ? 213 PHE A CA  1 
ATOM   956  C C   . PHE A 1 213 ? 140.938 162.037 166.141 1.00 52.17 ? 213 PHE A C   1 
ATOM   957  O O   . PHE A 1 213 ? 140.777 162.072 167.364 1.00 57.05 ? 213 PHE A O   1 
ATOM   958  C CB  . PHE A 1 213 ? 138.475 162.196 165.728 1.00 52.11 ? 213 PHE A CB  1 
ATOM   959  C CG  . PHE A 1 213 ? 137.345 162.718 164.890 1.00 50.60 ? 213 PHE A CG  1 
ATOM   960  C CD1 . PHE A 1 213 ? 137.375 164.007 164.383 1.00 55.61 ? 213 PHE A CD1 1 
ATOM   961  C CD2 . PHE A 1 213 ? 136.248 161.920 164.615 1.00 53.00 ? 213 PHE A CD2 1 
ATOM   962  C CE1 . PHE A 1 213 ? 136.333 164.487 163.611 1.00 56.15 ? 213 PHE A CE1 1 
ATOM   963  C CE2 . PHE A 1 213 ? 135.201 162.395 163.844 1.00 55.29 ? 213 PHE A CE2 1 
ATOM   964  C CZ  . PHE A 1 213 ? 135.245 163.680 163.342 1.00 56.88 ? 213 PHE A CZ  1 
ATOM   965  N N   . GLY A 1 214 ? 142.024 161.513 165.585 1.00 49.09 ? 214 GLY A N   1 
ATOM   966  C CA  . GLY A 1 214 ? 143.061 160.943 166.418 1.00 51.18 ? 214 GLY A CA  1 
ATOM   967  C C   . GLY A 1 214 ? 144.440 161.532 166.210 1.00 55.58 ? 214 GLY A C   1 
ATOM   968  O O   . GLY A 1 214 ? 145.284 161.467 167.109 1.00 54.52 ? 214 GLY A O   1 
ATOM   969  N N   . LEU A 1 215 ? 144.691 162.093 165.024 1.00 59.88 ? 215 LEU A N   1 
ATOM   970  C CA  . LEU A 1 215 ? 146.025 162.597 164.714 1.00 56.61 ? 215 LEU A CA  1 
ATOM   971  C C   . LEU A 1 215 ? 146.324 163.889 165.463 1.00 59.36 ? 215 LEU A C   1 
ATOM   972  O O   . LEU A 1 215 ? 147.425 164.062 165.997 1.00 61.52 ? 215 LEU A O   1 
ATOM   973  C CB  . LEU A 1 215 ? 146.173 162.802 163.209 1.00 54.29 ? 215 LEU A CB  1 
ATOM   974  C CG  . LEU A 1 215 ? 146.497 161.537 162.418 1.00 53.86 ? 215 LEU A CG  1 
ATOM   975  C CD1 . LEU A 1 215 ? 146.174 161.723 160.949 1.00 57.49 ? 215 LEU A CD1 1 
ATOM   976  C CD2 . LEU A 1 215 ? 147.952 161.174 162.605 1.00 54.26 ? 215 LEU A CD2 1 
ATOM   977  N N   . GLN A 1 216 ? 145.361 164.805 165.515 1.00 60.47 ? 216 GLN A N   1 
ATOM   978  C CA  . GLN A 1 216 ? 145.527 166.020 166.300 1.00 62.76 ? 216 GLN A CA  1 
ATOM   979  C C   . GLN A 1 216 ? 145.040 165.854 167.731 1.00 63.16 ? 216 GLN A C   1 
ATOM   980  O O   . GLN A 1 216 ? 145.583 166.490 168.642 1.00 61.47 ? 216 GLN A O   1 
ATOM   981  C CB  . GLN A 1 216 ? 144.788 167.184 165.636 1.00 63.46 ? 216 GLN A CB  1 
ATOM   982  N N   . ASP A 1 217 ? 144.034 165.007 167.948 1.00 64.60 ? 217 ASP A N   1 
ATOM   983  C CA  . ASP A 1 217 ? 143.494 164.765 169.280 1.00 64.19 ? 217 ASP A CA  1 
ATOM   984  C C   . ASP A 1 217 ? 144.034 163.458 169.847 1.00 65.39 ? 217 ASP A C   1 
ATOM   985  O O   . ASP A 1 217 ? 143.431 162.398 169.658 1.00 66.26 ? 217 ASP A O   1 
ATOM   986  C CB  . ASP A 1 217 ? 141.967 164.735 169.231 1.00 65.39 ? 217 ASP A CB  1 
ATOM   987  N N   . ASP A 1 218 ? 145.171 163.521 170.545 1.00 63.18 ? 218 ASP A N   1 
ATOM   988  C CA  . ASP A 1 218 ? 145.805 162.302 171.035 1.00 62.20 ? 218 ASP A CA  1 
ATOM   989  C C   . ASP A 1 218 ? 145.106 161.746 172.268 1.00 59.84 ? 218 ASP A C   1 
ATOM   990  O O   . ASP A 1 218 ? 145.345 160.594 172.646 1.00 60.45 ? 218 ASP A O   1 
ATOM   991  C CB  . ASP A 1 218 ? 147.280 162.567 171.344 1.00 60.12 ? 218 ASP A CB  1 
ATOM   992  N N   . SER A 1 219 ? 144.246 162.540 172.909 1.00 60.52 ? 219 SER A N   1 
ATOM   993  C CA  . SER A 1 219 ? 143.597 162.101 174.139 1.00 61.12 ? 219 SER A CA  1 
ATOM   994  C C   . SER A 1 219 ? 142.536 161.035 173.896 1.00 56.13 ? 219 SER A C   1 
ATOM   995  O O   . SER A 1 219 ? 142.223 160.270 174.815 1.00 54.75 ? 219 SER A O   1 
ATOM   996  C CB  . SER A 1 219 ? 142.972 163.298 174.858 1.00 59.68 ? 219 SER A CB  1 
ATOM   997  N N   . LYS A 1 220 ? 141.974 160.966 172.689 1.00 56.94 ? 220 LYS A N   1 
ATOM   998  C CA  . LYS A 1 220 ? 140.945 159.978 172.396 1.00 58.57 ? 220 LYS A CA  1 
ATOM   999  C C   . LYS A 1 220 ? 141.513 158.652 171.909 1.00 62.17 ? 220 LYS A C   1 
ATOM   1000 O O   . LYS A 1 220 ? 140.758 157.683 171.783 1.00 59.50 ? 220 LYS A O   1 
ATOM   1001 C CB  . LYS A 1 220 ? 139.969 160.529 171.354 1.00 54.65 ? 220 LYS A CB  1 
ATOM   1002 N N   . VAL A 1 221 ? 142.815 158.583 171.630 1.00 64.90 ? 221 VAL A N   1 
ATOM   1003 C CA  . VAL A 1 221 ? 143.423 157.361 171.113 1.00 61.22 ? 221 VAL A CA  1 
ATOM   1004 C C   . VAL A 1 221 ? 144.652 156.988 171.933 1.00 59.78 ? 221 VAL A C   1 
ATOM   1005 O O   . VAL A 1 221 ? 145.555 156.306 171.438 1.00 58.05 ? 221 VAL A O   1 
ATOM   1006 C CB  . VAL A 1 221 ? 143.779 157.504 169.622 1.00 58.38 ? 221 VAL A CB  1 
ATOM   1007 C CG1 . VAL A 1 221 ? 142.550 157.269 168.757 1.00 54.77 ? 221 VAL A CG1 1 
ATOM   1008 C CG2 . VAL A 1 221 ? 144.370 158.873 169.350 1.00 61.04 ? 221 VAL A CG2 1 
ATOM   1009 N N   . PHE A 1 222 ? 144.702 157.439 173.183 1.00 67.18 ? 222 PHE A N   1 
ATOM   1010 C CA  . PHE A 1 222 ? 145.739 157.041 174.124 1.00 67.24 ? 222 PHE A CA  1 
ATOM   1011 C C   . PHE A 1 222 ? 145.112 156.747 175.477 1.00 70.66 ? 222 PHE A C   1 
ATOM   1012 O O   . PHE A 1 222 ? 144.140 157.395 175.875 1.00 71.48 ? 222 PHE A O   1 
ATOM   1013 C CB  . PHE A 1 222 ? 146.808 158.123 174.295 1.00 69.52 ? 222 PHE A CB  1 
ATOM   1014 C CG  . PHE A 1 222 ? 147.993 157.966 173.387 1.00 69.38 ? 222 PHE A CG  1 
ATOM   1015 C CD1 . PHE A 1 222 ? 147.953 158.433 172.084 1.00 70.40 ? 222 PHE A CD1 1 
ATOM   1016 C CD2 . PHE A 1 222 ? 149.157 157.367 173.846 1.00 66.82 ? 222 PHE A CD2 1 
ATOM   1017 C CE1 . PHE A 1 222 ? 149.048 158.301 171.256 1.00 70.27 ? 222 PHE A CE1 1 
ATOM   1018 C CE2 . PHE A 1 222 ? 150.255 157.229 173.020 1.00 66.22 ? 222 PHE A CE2 1 
ATOM   1019 C CZ  . PHE A 1 222 ? 150.200 157.695 171.724 1.00 67.99 ? 222 PHE A CZ  1 
ATOM   1020 N N   . LYS A 1 223 ? 145.680 155.776 176.185 1.00 75.05 ? 223 LYS A N   1 
ATOM   1021 C CA  . LYS A 1 223 ? 145.258 155.455 177.541 1.00 75.61 ? 223 LYS A CA  1 
ATOM   1022 C C   . LYS A 1 223 ? 146.483 155.061 178.349 1.00 76.43 ? 223 LYS A C   1 
ATOM   1023 O O   . LYS A 1 223 ? 147.032 153.973 178.145 1.00 76.36 ? 223 LYS A O   1 
ATOM   1024 C CB  . LYS A 1 223 ? 144.223 154.326 177.553 1.00 76.80 ? 223 LYS A CB  1 
ATOM   1025 N N   . GLU A 1 224 ? 146.893 155.956 179.259 1.00 77.67 ? 224 GLU A N   1 
ATOM   1026 C CA  . GLU A 1 224 ? 148.073 155.798 180.123 1.00 77.31 ? 224 GLU A CA  1 
ATOM   1027 C C   . GLU A 1 224 ? 149.349 155.550 179.318 1.00 76.42 ? 224 GLU A C   1 
ATOM   1028 O O   . GLU A 1 224 ? 150.181 154.718 179.686 1.00 76.30 ? 224 GLU A O   1 
ATOM   1029 C CB  . GLU A 1 224 ? 147.865 154.693 181.165 1.00 76.06 ? 224 GLU A CB  1 
ATOM   1030 N N   . GLY A 1 225 ? 149.513 156.277 178.216 1.00 77.78 ? 225 GLY A N   1 
ATOM   1031 C CA  . GLY A 1 225 ? 150.714 156.159 177.414 1.00 78.47 ? 225 GLY A CA  1 
ATOM   1032 C C   . GLY A 1 225 ? 150.780 154.950 176.511 1.00 79.99 ? 225 GLY A C   1 
ATOM   1033 O O   . GLY A 1 225 ? 151.878 154.552 176.113 1.00 82.25 ? 225 GLY A O   1 
ATOM   1034 N N   . SER A 1 226 ? 149.642 154.349 176.176 1.00 77.45 ? 226 SER A N   1 
ATOM   1035 C CA  . SER A 1 226 ? 149.589 153.212 175.271 1.00 77.75 ? 226 SER A CA  1 
ATOM   1036 C C   . SER A 1 226 ? 148.491 153.437 174.243 1.00 78.26 ? 226 SER A C   1 
ATOM   1037 O O   . SER A 1 226 ? 147.504 154.126 174.514 1.00 79.87 ? 226 SER A O   1 
ATOM   1038 C CB  . SER A 1 226 ? 149.336 151.902 176.026 1.00 76.72 ? 226 SER A CB  1 
ATOM   1039 O OG  . SER A 1 226 ? 148.019 151.860 176.545 1.00 77.61 ? 226 SER A OG  1 
ATOM   1040 N N   . CYS A 1 227 ? 148.669 152.856 173.058 1.00 67.22 ? 227 CYS A N   1 
ATOM   1041 C CA  . CYS A 1 227 ? 147.666 152.986 172.009 1.00 65.71 ? 227 CYS A CA  1 
ATOM   1042 C C   . CYS A 1 227 ? 146.454 152.129 172.338 1.00 65.28 ? 227 CYS A C   1 
ATOM   1043 O O   . CYS A 1 227 ? 146.526 150.897 172.305 1.00 68.25 ? 227 CYS A O   1 
ATOM   1044 C CB  . CYS A 1 227 ? 148.241 152.588 170.654 1.00 62.11 ? 227 CYS A CB  1 
ATOM   1045 S SG  . CYS A 1 227 ? 149.202 153.867 169.839 1.00 79.04 ? 227 CYS A SG  1 
ATOM   1046 N N   . LEU A 1 228 ? 145.343 152.784 172.650 1.00 55.38 ? 228 LEU A N   1 
ATOM   1047 C CA  . LEU A 1 228 ? 144.084 152.100 172.889 1.00 50.22 ? 228 LEU A CA  1 
ATOM   1048 C C   . LEU A 1 228 ? 142.960 153.058 172.535 1.00 53.85 ? 228 LEU A C   1 
ATOM   1049 O O   . LEU A 1 228 ? 143.133 154.278 172.553 1.00 56.54 ? 228 LEU A O   1 
ATOM   1050 C CB  . LEU A 1 228 ? 143.964 151.628 174.341 1.00 49.38 ? 228 LEU A CB  1 
ATOM   1051 N N   . LEU A 1 229 ? 141.805 152.490 172.203 1.00 52.72 ? 229 LEU A N   1 
ATOM   1052 C CA  . LEU A 1 229 ? 140.635 153.310 171.927 1.00 52.24 ? 229 LEU A CA  1 
ATOM   1053 C C   . LEU A 1 229 ? 139.992 153.771 173.226 1.00 57.64 ? 229 LEU A C   1 
ATOM   1054 O O   . LEU A 1 229 ? 139.123 153.085 173.774 1.00 56.88 ? 229 LEU A O   1 
ATOM   1055 C CB  . LEU A 1 229 ? 139.625 152.544 171.076 1.00 47.70 ? 229 LEU A CB  1 
ATOM   1056 C CG  . LEU A 1 229 ? 139.883 152.540 169.574 1.00 47.50 ? 229 LEU A CG  1 
ATOM   1057 C CD1 . LEU A 1 229 ? 138.868 151.669 168.867 1.00 51.23 ? 229 LEU A CD1 1 
ATOM   1058 C CD2 . LEU A 1 229 ? 139.836 153.953 169.036 1.00 52.06 ? 229 LEU A CD2 1 
ATOM   1059 N N   . ALA A 1 230 ? 140.421 154.929 173.733 1.00 55.05 ? 230 ALA A N   1 
ATOM   1060 C CA  . ALA A 1 230 ? 139.841 155.464 174.957 1.00 52.59 ? 230 ALA A CA  1 
ATOM   1061 C C   . ALA A 1 230 ? 138.438 156.010 174.741 1.00 56.94 ? 230 ALA A C   1 
ATOM   1062 O O   . ALA A 1 230 ? 137.661 156.081 175.698 1.00 59.33 ? 230 ALA A O   1 
ATOM   1063 C CB  . ALA A 1 230 ? 140.740 156.556 175.534 1.00 51.63 ? 230 ALA A CB  1 
ATOM   1064 N N   . ASP A 1 231 ? 138.095 156.393 173.511 1.00 53.64 ? 231 ASP A N   1 
ATOM   1065 C CA  . ASP A 1 231 ? 136.764 156.910 173.197 1.00 53.65 ? 231 ASP A CA  1 
ATOM   1066 C C   . ASP A 1 231 ? 135.791 155.737 173.145 1.00 50.84 ? 231 ASP A C   1 
ATOM   1067 O O   . ASP A 1 231 ? 135.607 155.080 172.118 1.00 44.77 ? 231 ASP A O   1 
ATOM   1068 C CB  . ASP A 1 231 ? 136.783 157.680 171.882 1.00 52.27 ? 231 ASP A CB  1 
ATOM   1069 N N   . ASP A 1 232 ? 135.149 155.477 174.289 1.00 46.99 ? 232 ASP A N   1 
ATOM   1070 C CA  . ASP A 1 232 ? 134.249 154.332 174.400 1.00 46.91 ? 232 ASP A CA  1 
ATOM   1071 C C   . ASP A 1 232 ? 132.955 154.549 173.628 1.00 50.34 ? 232 ASP A C   1 
ATOM   1072 O O   . ASP A 1 232 ? 132.276 153.575 173.270 1.00 53.52 ? 232 ASP A O   1 
ATOM   1073 C CB  . ASP A 1 232 ? 133.948 154.045 175.871 1.00 42.65 ? 232 ASP A CB  1 
ATOM   1074 N N   . ASN A 1 233 ? 132.597 155.810 173.368 1.00 45.05 ? 233 ASN A N   1 
ATOM   1075 C CA  . ASN A 1 233 ? 131.436 156.103 172.536 1.00 44.57 ? 233 ASN A CA  1 
ATOM   1076 C C   . ASN A 1 233 ? 131.658 155.655 171.100 1.00 46.40 ? 233 ASN A C   1 
ATOM   1077 O O   . ASN A 1 233 ? 130.702 155.287 170.408 1.00 43.32 ? 233 ASN A O   1 
ATOM   1078 C CB  . ASN A 1 233 ? 131.116 157.597 172.588 1.00 46.04 ? 233 ASN A CB  1 
ATOM   1079 N N   . PHE A 1 234 ? 132.907 155.688 170.633 1.00 49.59 ? 234 PHE A N   1 
ATOM   1080 C CA  . PHE A 1 234 ? 133.248 155.028 169.379 1.00 52.67 ? 234 PHE A CA  1 
ATOM   1081 C C   . PHE A 1 234 ? 133.210 153.513 169.530 1.00 50.67 ? 234 PHE A C   1 
ATOM   1082 O O   . PHE A 1 234 ? 132.744 152.815 168.628 1.00 45.20 ? 234 PHE A O   1 
ATOM   1083 C CB  . PHE A 1 234 ? 134.630 155.481 168.896 1.00 50.36 ? 234 PHE A CB  1 
ATOM   1084 C CG  . PHE A 1 234 ? 135.113 154.765 167.655 1.00 54.36 ? 234 PHE A CG  1 
ATOM   1085 C CD1 . PHE A 1 234 ? 134.291 154.618 166.542 1.00 51.76 ? 234 PHE A CD1 1 
ATOM   1086 C CD2 . PHE A 1 234 ? 136.393 154.235 167.608 1.00 52.83 ? 234 PHE A CD2 1 
ATOM   1087 C CE1 . PHE A 1 234 ? 134.739 153.952 165.414 1.00 46.61 ? 234 PHE A CE1 1 
ATOM   1088 C CE2 . PHE A 1 234 ? 136.846 153.573 166.481 1.00 52.13 ? 234 PHE A CE2 1 
ATOM   1089 C CZ  . PHE A 1 234 ? 136.019 153.432 165.385 1.00 46.86 ? 234 PHE A CZ  1 
ATOM   1090 N N   . VAL A 1 235 ? 133.684 152.998 170.673 1.00 45.25 ? 235 VAL A N   1 
ATOM   1091 C CA  . VAL A 1 235 ? 133.913 151.562 170.841 1.00 36.06 ? 235 VAL A CA  1 
ATOM   1092 C C   . VAL A 1 235 ? 132.602 150.788 170.820 1.00 33.72 ? 235 VAL A C   1 
ATOM   1093 O O   . VAL A 1 235 ? 132.473 149.790 170.100 1.00 44.89 ? 235 VAL A O   1 
ATOM   1094 C CB  . VAL A 1 235 ? 134.701 151.299 172.138 1.00 38.86 ? 235 VAL A CB  1 
ATOM   1095 C CG1 . VAL A 1 235 ? 134.700 149.824 172.486 1.00 34.03 ? 235 VAL A CG1 1 
ATOM   1096 C CG2 . VAL A 1 235 ? 136.120 151.793 171.996 1.00 40.56 ? 235 VAL A CG2 1 
ATOM   1097 N N   . LEU A 1 236 ? 131.601 151.259 171.569 1.00 29.97 ? 236 LEU A N   1 
ATOM   1098 C CA  . LEU A 1 236 ? 130.330 150.544 171.689 1.00 36.86 ? 236 LEU A CA  1 
ATOM   1099 C C   . LEU A 1 236 ? 129.572 150.510 170.362 1.00 38.97 ? 236 LEU A C   1 
ATOM   1100 O O   . LEU A 1 236 ? 129.166 149.438 169.890 1.00 36.83 ? 236 LEU A O   1 
ATOM   1101 C CB  . LEU A 1 236 ? 129.482 151.194 172.788 1.00 35.16 ? 236 LEU A CB  1 
ATOM   1102 C CG  . LEU A 1 236 ? 128.422 150.358 173.508 1.00 37.93 ? 236 LEU A CG  1 
ATOM   1103 C CD1 . LEU A 1 236 ? 128.337 150.784 174.959 1.00 35.30 ? 236 LEU A CD1 1 
ATOM   1104 C CD2 . LEU A 1 236 ? 127.062 150.497 172.846 1.00 39.15 ? 236 LEU A CD2 1 
ATOM   1105 N N   . ILE A 1 237 ? 129.423 151.675 169.725 1.00 40.22 ? 237 ILE A N   1 
ATOM   1106 C CA  . ILE A 1 237 ? 128.711 151.758 168.455 1.00 37.70 ? 237 ILE A CA  1 
ATOM   1107 C C   . ILE A 1 237 ? 129.482 151.060 167.342 1.00 41.56 ? 237 ILE A C   1 
ATOM   1108 O O   . ILE A 1 237 ? 128.875 150.416 166.479 1.00 39.74 ? 237 ILE A O   1 
ATOM   1109 C CB  . ILE A 1 237 ? 128.422 153.228 168.100 1.00 38.58 ? 237 ILE A CB  1 
ATOM   1110 N N   . GLY A 1 238 ? 130.816 151.153 167.350 1.00 42.77 ? 238 GLY A N   1 
ATOM   1111 C CA  . GLY A 1 238 ? 131.611 150.502 166.324 1.00 36.11 ? 238 GLY A CA  1 
ATOM   1112 C C   . GLY A 1 238 ? 131.585 148.991 166.427 1.00 31.28 ? 238 GLY A C   1 
ATOM   1113 O O   . GLY A 1 238 ? 131.547 148.298 165.411 1.00 31.85 ? 238 GLY A O   1 
ATOM   1114 N N   . SER A 1 239 ? 131.600 148.459 167.655 1.00 26.65 ? 239 SER A N   1 
ATOM   1115 C CA  . SER A 1 239 ? 131.408 147.024 167.838 1.00 18.27 ? 239 SER A CA  1 
ATOM   1116 C C   . SER A 1 239 ? 130.012 146.603 167.410 1.00 27.59 ? 239 SER A C   1 
ATOM   1117 O O   . SER A 1 239 ? 129.835 145.524 166.830 1.00 37.82 ? 239 SER A O   1 
ATOM   1118 C CB  . SER A 1 239 ? 131.657 146.632 169.293 1.00 20.36 ? 239 SER A CB  1 
ATOM   1119 O OG  . SER A 1 239 ? 133.023 146.769 169.636 1.00 31.86 ? 239 SER A OG  1 
ATOM   1120 N N   . PHE A 1 240 ? 129.015 147.459 167.660 1.00 27.86 ? 240 PHE A N   1 
ATOM   1121 C CA  . PHE A 1 240 ? 127.639 147.151 167.276 1.00 33.38 ? 240 PHE A CA  1 
ATOM   1122 C C   . PHE A 1 240 ? 127.470 147.078 165.759 1.00 35.60 ? 240 PHE A C   1 
ATOM   1123 O O   . PHE A 1 240 ? 126.729 146.229 165.251 1.00 36.11 ? 240 PHE A O   1 
ATOM   1124 C CB  . PHE A 1 240 ? 126.693 148.188 167.874 1.00 35.90 ? 240 PHE A CB  1 
ATOM   1125 C CG  . PHE A 1 240 ? 125.244 147.860 167.690 1.00 39.82 ? 240 PHE A CG  1 
ATOM   1126 C CD1 . PHE A 1 240 ? 124.644 146.874 168.456 1.00 35.53 ? 240 PHE A CD1 1 
ATOM   1127 C CD2 . PHE A 1 240 ? 124.477 148.546 166.760 1.00 39.94 ? 240 PHE A CD2 1 
ATOM   1128 C CE1 . PHE A 1 240 ? 123.307 146.571 168.293 1.00 36.44 ? 240 PHE A CE1 1 
ATOM   1129 C CE2 . PHE A 1 240 ? 123.138 148.250 166.591 1.00 36.89 ? 240 PHE A CE2 1 
ATOM   1130 C CZ  . PHE A 1 240 ? 122.552 147.261 167.359 1.00 36.01 ? 240 PHE A CZ  1 
ATOM   1131 N N   . VAL A 1 241 ? 128.138 147.958 165.015 1.00 36.69 ? 241 VAL A N   1 
ATOM   1132 C CA  . VAL A 1 241 ? 127.984 147.904 163.560 1.00 31.26 ? 241 VAL A CA  1 
ATOM   1133 C C   . VAL A 1 241 ? 128.999 146.965 162.916 1.00 29.26 ? 241 VAL A C   1 
ATOM   1134 O O   . VAL A 1 241 ? 128.800 146.533 161.777 1.00 30.73 ? 241 VAL A O   1 
ATOM   1135 C CB  . VAL A 1 241 ? 128.081 149.293 162.904 1.00 38.43 ? 241 VAL A CB  1 
ATOM   1136 C CG1 . VAL A 1 241 ? 126.786 150.084 163.094 1.00 38.80 ? 241 VAL A CG1 1 
ATOM   1137 C CG2 . VAL A 1 241 ? 129.335 150.043 163.333 1.00 32.65 ? 241 VAL A CG2 1 
ATOM   1138 N N   . SER A 1 242 ? 130.088 146.635 163.615 1.00 36.70 ? 242 SER A N   1 
ATOM   1139 C CA  . SER A 1 242 ? 131.183 145.921 162.976 1.00 38.50 ? 242 SER A CA  1 
ATOM   1140 C C   . SER A 1 242 ? 131.141 144.429 163.262 1.00 32.14 ? 242 SER A C   1 
ATOM   1141 O O   . SER A 1 242 ? 131.559 143.633 162.416 1.00 24.81 ? 242 SER A O   1 
ATOM   1142 C CB  . SER A 1 242 ? 132.518 146.510 163.436 1.00 28.76 ? 242 SER A CB  1 
ATOM   1143 O OG  . SER A 1 242 ? 133.605 145.907 162.763 1.00 31.88 ? 242 SER A OG  1 
ATOM   1144 N N   . PHE A 1 243 ? 130.670 144.022 164.440 1.00 20.01 ? 243 PHE A N   1 
ATOM   1145 C CA  . PHE A 1 243 ? 130.685 142.598 164.734 1.00 14.63 ? 243 PHE A CA  1 
ATOM   1146 C C   . PHE A 1 243 ? 129.302 142.062 165.063 1.00 27.99 ? 243 PHE A C   1 
ATOM   1147 O O   . PHE A 1 243 ? 128.922 141.000 164.564 1.00 44.70 ? 243 PHE A O   1 
ATOM   1148 C CB  . PHE A 1 243 ? 131.646 142.298 165.882 1.00 16.01 ? 243 PHE A CB  1 
ATOM   1149 C CG  . PHE A 1 243 ? 131.703 140.846 166.262 1.00 24.71 ? 243 PHE A CG  1 
ATOM   1150 C CD1 . PHE A 1 243 ? 132.330 139.926 165.440 1.00 29.39 ? 243 PHE A CD1 1 
ATOM   1151 C CD2 . PHE A 1 243 ? 131.140 140.403 167.449 1.00 26.47 ? 243 PHE A CD2 1 
ATOM   1152 C CE1 . PHE A 1 243 ? 132.388 138.590 165.787 1.00 22.02 ? 243 PHE A CE1 1 
ATOM   1153 C CE2 . PHE A 1 243 ? 131.196 139.067 167.802 1.00 29.29 ? 243 PHE A CE2 1 
ATOM   1154 C CZ  . PHE A 1 243 ? 131.824 138.160 166.969 1.00 22.92 ? 243 PHE A CZ  1 
ATOM   1155 N N   . PHE A 1 244 ? 128.536 142.782 165.883 1.00 13.26 ? 244 PHE A N   1 
ATOM   1156 C CA  . PHE A 1 244 ? 127.333 142.185 166.455 1.00 23.15 ? 244 PHE A CA  1 
ATOM   1157 C C   . PHE A 1 244 ? 126.169 142.153 165.469 1.00 30.68 ? 244 PHE A C   1 
ATOM   1158 O O   . PHE A 1 244 ? 125.375 141.206 165.489 1.00 31.19 ? 244 PHE A O   1 
ATOM   1159 C CB  . PHE A 1 244 ? 126.962 142.914 167.741 1.00 20.33 ? 244 PHE A CB  1 
ATOM   1160 C CG  . PHE A 1 244 ? 127.730 142.426 168.933 1.00 22.48 ? 244 PHE A CG  1 
ATOM   1161 C CD1 . PHE A 1 244 ? 127.290 141.332 169.656 1.00 28.03 ? 244 PHE A CD1 1 
ATOM   1162 C CD2 . PHE A 1 244 ? 128.921 143.029 169.299 1.00 27.65 ? 244 PHE A CD2 1 
ATOM   1163 C CE1 . PHE A 1 244 ? 128.007 140.870 170.743 1.00 31.39 ? 244 PHE A CE1 1 
ATOM   1164 C CE2 . PHE A 1 244 ? 129.643 142.568 170.381 1.00 21.50 ? 244 PHE A CE2 1 
ATOM   1165 C CZ  . PHE A 1 244 ? 129.185 141.491 171.103 1.00 23.43 ? 244 PHE A CZ  1 
ATOM   1166 N N   . ILE A 1 245 ? 126.056 143.143 164.591 1.00 30.36 ? 245 ILE A N   1 
ATOM   1167 C CA  . ILE A 1 245 ? 125.081 143.057 163.503 1.00 23.98 ? 245 ILE A CA  1 
ATOM   1168 C C   . ILE A 1 245 ? 125.552 142.077 162.424 1.00 17.98 ? 245 ILE A C   1 
ATOM   1169 O O   . ILE A 1 245 ? 124.705 141.338 161.898 1.00 16.07 ? 245 ILE A O   1 
ATOM   1170 C CB  . ILE A 1 245 ? 124.749 144.446 162.927 1.00 25.52 ? 245 ILE A CB  1 
ATOM   1171 N N   . PRO A 1 246 ? 126.852 141.993 162.050 1.00 24.87 ? 246 PRO A N   1 
ATOM   1172 C CA  . PRO A 1 246 ? 127.285 140.806 161.288 1.00 17.98 ? 246 PRO A CA  1 
ATOM   1173 C C   . PRO A 1 246 ? 127.073 139.480 161.995 1.00 19.98 ? 246 PRO A C   1 
ATOM   1174 O O   . PRO A 1 246 ? 126.775 138.491 161.324 1.00 33.70 ? 246 PRO A O   1 
ATOM   1175 C CB  . PRO A 1 246 ? 128.771 141.079 161.046 1.00 20.76 ? 246 PRO A CB  1 
ATOM   1176 C CG  . PRO A 1 246 ? 128.843 142.497 160.924 1.00 28.10 ? 246 PRO A CG  1 
ATOM   1177 C CD  . PRO A 1 246 ? 127.885 143.048 161.931 1.00 32.62 ? 246 PRO A CD  1 
ATOM   1178 N N   . LEU A 1 247 ? 127.218 139.424 163.322 1.00 5.82  ? 247 LEU A N   1 
ATOM   1179 C CA  . LEU A 1 247 ? 126.964 138.173 164.030 1.00 11.29 ? 247 LEU A CA  1 
ATOM   1180 C C   . LEU A 1 247 ? 125.493 137.785 163.959 1.00 24.45 ? 247 LEU A C   1 
ATOM   1181 O O   . LEU A 1 247 ? 125.165 136.620 163.710 1.00 31.56 ? 247 LEU A O   1 
ATOM   1182 C CB  . LEU A 1 247 ? 127.415 138.278 165.484 1.00 11.77 ? 247 LEU A CB  1 
ATOM   1183 C CG  . LEU A 1 247 ? 127.317 136.994 166.304 1.00 20.69 ? 247 LEU A CG  1 
ATOM   1184 C CD1 . LEU A 1 247 ? 128.298 135.962 165.786 1.00 20.66 ? 247 LEU A CD1 1 
ATOM   1185 C CD2 . LEU A 1 247 ? 127.561 137.276 167.773 1.00 20.58 ? 247 LEU A CD2 1 
ATOM   1186 N N   . THR A 1 248 ? 124.589 138.754 164.129 1.00 23.27 ? 248 THR A N   1 
ATOM   1187 C CA  . THR A 1 248 ? 123.167 138.443 164.033 1.00 19.25 ? 248 THR A CA  1 
ATOM   1188 C C   . THR A 1 248 ? 122.709 138.242 162.593 1.00 21.00 ? 248 THR A C   1 
ATOM   1189 O O   . THR A 1 248 ? 121.612 137.718 162.378 1.00 23.22 ? 248 THR A O   1 
ATOM   1190 C CB  . THR A 1 248 ? 122.328 139.528 164.723 1.00 20.15 ? 248 THR A CB  1 
ATOM   1191 O OG1 . THR A 1 248 ? 121.088 138.963 165.163 1.00 22.82 ? 248 THR A OG1 1 
ATOM   1192 C CG2 . THR A 1 248 ? 122.040 140.701 163.797 1.00 17.92 ? 248 THR A CG2 1 
ATOM   1193 N N   . ILE A 1 249 ? 123.513 138.639 161.603 1.00 27.86 ? 249 ILE A N   1 
ATOM   1194 C CA  . ILE A 1 249 ? 123.211 138.257 160.225 1.00 21.44 ? 249 ILE A CA  1 
ATOM   1195 C C   . ILE A 1 249 ? 123.691 136.835 159.948 1.00 19.18 ? 249 ILE A C   1 
ATOM   1196 O O   . ILE A 1 249 ? 122.950 136.014 159.393 1.00 31.93 ? 249 ILE A O   1 
ATOM   1197 C CB  . ILE A 1 249 ? 123.814 139.272 159.237 1.00 24.84 ? 249 ILE A CB  1 
ATOM   1198 C CG1 . ILE A 1 249 ? 122.961 140.538 159.195 1.00 27.23 ? 249 ILE A CG1 1 
ATOM   1199 C CG2 . ILE A 1 249 ? 123.927 138.694 157.837 1.00 18.72 ? 249 ILE A CG2 1 
ATOM   1200 C CD1 . ILE A 1 249 ? 123.645 141.699 158.522 1.00 28.18 ? 249 ILE A CD1 1 
ATOM   1201 N N   . MET A 1 250 ? 124.926 136.514 160.351 1.00 13.23 ? 250 MET A N   1 
ATOM   1202 C CA  . MET A 1 250 ? 125.486 135.209 160.012 1.00 17.36 ? 250 MET A CA  1 
ATOM   1203 C C   . MET A 1 250 ? 124.874 134.077 160.824 1.00 20.98 ? 250 MET A C   1 
ATOM   1204 O O   . MET A 1 250 ? 124.834 132.946 160.338 1.00 29.42 ? 250 MET A O   1 
ATOM   1205 C CB  . MET A 1 250 ? 127.007 135.186 160.160 1.00 18.26 ? 250 MET A CB  1 
ATOM   1206 C CG  . MET A 1 250 ? 127.754 136.190 159.305 1.00 27.38 ? 250 MET A CG  1 
ATOM   1207 S SD  . MET A 1 250 ? 129.526 136.186 159.630 1.00 51.69 ? 250 MET A SD  1 
ATOM   1208 C CE  . MET A 1 250 ? 129.817 134.436 159.877 1.00 20.90 ? 250 MET A CE  1 
ATOM   1209 N N   . VAL A 1 251 ? 124.376 134.348 162.035 1.00 10.85 ? 251 VAL A N   1 
ATOM   1210 C CA  . VAL A 1 251 ? 123.652 133.314 162.775 1.00 17.44 ? 251 VAL A CA  1 
ATOM   1211 C C   . VAL A 1 251 ? 122.358 132.945 162.054 1.00 19.68 ? 251 VAL A C   1 
ATOM   1212 O O   . VAL A 1 251 ? 122.044 131.759 161.884 1.00 20.12 ? 251 VAL A O   1 
ATOM   1213 C CB  . VAL A 1 251 ? 123.400 133.772 164.225 1.00 18.55 ? 251 VAL A CB  1 
ATOM   1214 C CG1 . VAL A 1 251 ? 122.313 132.945 164.887 1.00 22.95 ? 251 VAL A CG1 1 
ATOM   1215 C CG2 . VAL A 1 251 ? 124.675 133.659 165.035 1.00 16.98 ? 251 VAL A CG2 1 
ATOM   1216 N N   . ILE A 1 252 ? 121.625 133.949 161.565 1.00 17.41 ? 252 ILE A N   1 
ATOM   1217 C CA  . ILE A 1 252 ? 120.381 133.704 160.838 1.00 22.75 ? 252 ILE A CA  1 
ATOM   1218 C C   . ILE A 1 252 ? 120.650 133.006 159.506 1.00 24.13 ? 252 ILE A C   1 
ATOM   1219 O O   . ILE A 1 252 ? 119.952 132.050 159.145 1.00 25.03 ? 252 ILE A O   1 
ATOM   1220 C CB  . ILE A 1 252 ? 119.608 135.025 160.657 1.00 21.50 ? 252 ILE A CB  1 
ATOM   1221 C CG1 . ILE A 1 252 ? 119.066 135.509 162.000 1.00 23.69 ? 252 ILE A CG1 1 
ATOM   1222 C CG2 . ILE A 1 252 ? 118.459 134.873 159.680 1.00 21.95 ? 252 ILE A CG2 1 
ATOM   1223 C CD1 . ILE A 1 252 ? 118.420 136.871 161.935 1.00 24.66 ? 252 ILE A CD1 1 
ATOM   1224 N N   . THR A 1 253 ? 121.681 133.438 158.770 1.00 20.54 ? 253 THR A N   1 
ATOM   1225 C CA  . THR A 1 253 ? 121.959 132.805 157.481 1.00 10.04 ? 253 THR A CA  1 
ATOM   1226 C C   . THR A 1 253 ? 122.522 131.399 157.650 1.00 19.06 ? 253 THR A C   1 
ATOM   1227 O O   . THR A 1 253 ? 122.227 130.518 156.839 1.00 26.82 ? 253 THR A O   1 
ATOM   1228 C CB  . THR A 1 253 ? 122.909 133.651 156.640 1.00 14.15 ? 253 THR A CB  1 
ATOM   1229 O OG1 . THR A 1 253 ? 124.136 133.848 157.346 1.00 27.84 ? 253 THR A OG1 1 
ATOM   1230 C CG2 . THR A 1 253 ? 122.281 134.990 156.314 1.00 25.81 ? 253 THR A CG2 1 
ATOM   1231 N N   . TYR A 1 254 ? 123.306 131.154 158.705 1.00 20.66 ? 254 TYR A N   1 
ATOM   1232 C CA  . TYR A 1 254 ? 123.779 129.802 158.983 1.00 14.86 ? 254 TYR A CA  1 
ATOM   1233 C C   . TYR A 1 254 ? 122.632 128.887 159.380 1.00 20.64 ? 254 TYR A C   1 
ATOM   1234 O O   . TYR A 1 254 ? 122.570 127.732 158.942 1.00 35.98 ? 254 TYR A O   1 
ATOM   1235 C CB  . TYR A 1 254 ? 124.835 129.829 160.084 1.00 16.27 ? 254 TYR A CB  1 
ATOM   1236 C CG  . TYR A 1 254 ? 125.211 128.460 160.593 1.00 20.72 ? 254 TYR A CG  1 
ATOM   1237 C CD1 . TYR A 1 254 ? 125.935 127.582 159.801 1.00 30.49 ? 254 TYR A CD1 1 
ATOM   1238 C CD2 . TYR A 1 254 ? 124.847 128.047 161.867 1.00 21.54 ? 254 TYR A CD2 1 
ATOM   1239 C CE1 . TYR A 1 254 ? 126.288 126.326 160.262 1.00 27.34 ? 254 TYR A CE1 1 
ATOM   1240 C CE2 . TYR A 1 254 ? 125.193 126.793 162.336 1.00 25.63 ? 254 TYR A CE2 1 
ATOM   1241 C CZ  . TYR A 1 254 ? 125.914 125.938 161.528 1.00 28.17 ? 254 TYR A CZ  1 
ATOM   1242 O OH  . TYR A 1 254 ? 126.264 124.690 161.985 1.00 27.98 ? 254 TYR A OH  1 
ATOM   1243 N N   . PHE A 1 255 ? 121.707 129.393 160.204 1.00 16.95 ? 255 PHE A N   1 
ATOM   1244 C CA  . PHE A 1 255 ? 120.551 128.603 160.615 1.00 26.51 ? 255 PHE A CA  1 
ATOM   1245 C C   . PHE A 1 255 ? 119.656 128.273 159.427 1.00 29.44 ? 255 PHE A C   1 
ATOM   1246 O O   . PHE A 1 255 ? 119.214 127.130 159.270 1.00 29.41 ? 255 PHE A O   1 
ATOM   1247 C CB  . PHE A 1 255 ? 119.768 129.353 161.692 1.00 25.21 ? 255 PHE A CB  1 
ATOM   1248 C CG  . PHE A 1 255 ? 118.449 128.726 162.031 1.00 25.75 ? 255 PHE A CG  1 
ATOM   1249 C CD1 . PHE A 1 255 ? 118.388 127.445 162.554 1.00 31.61 ? 255 PHE A CD1 1 
ATOM   1250 C CD2 . PHE A 1 255 ? 117.267 129.420 161.830 1.00 26.07 ? 255 PHE A CD2 1 
ATOM   1251 C CE1 . PHE A 1 255 ? 117.171 126.866 162.868 1.00 34.43 ? 255 PHE A CE1 1 
ATOM   1252 C CE2 . PHE A 1 255 ? 116.047 128.849 162.140 1.00 31.87 ? 255 PHE A CE2 1 
ATOM   1253 C CZ  . PHE A 1 255 ? 116.000 127.570 162.660 1.00 33.27 ? 255 PHE A CZ  1 
ATOM   1254 N N   . LEU A 1 256 ? 119.422 129.247 158.546 1.00 21.63 ? 256 LEU A N   1 
ATOM   1255 C CA  . LEU A 1 256 ? 118.568 128.988 157.393 1.00 15.02 ? 256 LEU A CA  1 
ATOM   1256 C C   . LEU A 1 256 ? 119.286 128.188 156.311 1.00 20.85 ? 256 LEU A C   1 
ATOM   1257 O O   . LEU A 1 256 ? 118.628 127.530 155.499 1.00 35.91 ? 256 LEU A O   1 
ATOM   1258 C CB  . LEU A 1 256 ? 118.033 130.300 156.827 1.00 20.44 ? 256 LEU A CB  1 
ATOM   1259 C CG  . LEU A 1 256 ? 117.109 131.087 157.757 1.00 24.29 ? 256 LEU A CG  1 
ATOM   1260 C CD1 . LEU A 1 256 ? 116.583 132.328 157.063 1.00 23.85 ? 256 LEU A CD1 1 
ATOM   1261 C CD2 . LEU A 1 256 ? 115.970 130.220 158.248 1.00 25.53 ? 256 LEU A CD2 1 
ATOM   1262 N N   . THR A 1 257 ? 120.620 128.210 156.280 1.00 20.89 ? 257 THR A N   1 
ATOM   1263 C CA  . THR A 1 257 ? 121.346 127.373 155.331 1.00 15.03 ? 257 THR A CA  1 
ATOM   1264 C C   . THR A 1 257 ? 121.364 125.921 155.793 1.00 18.85 ? 257 THR A C   1 
ATOM   1265 O O   . THR A 1 257 ? 121.279 124.998 154.975 1.00 30.45 ? 257 THR A O   1 
ATOM   1266 C CB  . THR A 1 257 ? 122.766 127.904 155.140 1.00 18.80 ? 257 THR A CB  1 
ATOM   1267 O OG1 . THR A 1 257 ? 122.717 129.311 154.887 1.00 30.99 ? 257 THR A OG1 1 
ATOM   1268 C CG2 . THR A 1 257 ? 123.431 127.236 153.959 1.00 18.81 ? 257 THR A CG2 1 
ATOM   1269 N N   . ILE A 1 258 ? 121.470 125.699 157.106 1.00 14.07 ? 258 ILE A N   1 
ATOM   1270 C CA  . ILE A 1 258 ? 121.318 124.350 157.646 1.00 12.42 ? 258 ILE A CA  1 
ATOM   1271 C C   . ILE A 1 258 ? 119.881 123.867 157.466 1.00 24.28 ? 258 ILE A C   1 
ATOM   1272 O O   . ILE A 1 258 ? 119.637 122.695 157.147 1.00 29.01 ? 258 ILE A O   1 
ATOM   1273 C CB  . ILE A 1 258 ? 121.770 124.320 159.119 1.00 20.37 ? 258 ILE A CB  1 
ATOM   1274 C CG1 . ILE A 1 258 ? 123.276 124.564 159.209 1.00 23.11 ? 258 ILE A CG1 1 
ATOM   1275 C CG2 . ILE A 1 258 ? 121.444 123.000 159.791 1.00 30.91 ? 258 ILE A CG2 1 
ATOM   1276 C CD1 . ILE A 1 258 ? 124.108 123.517 158.523 1.00 19.96 ? 258 ILE A CD1 1 
ATOM   1277 N N   . LYS A 1 259 ? 118.911 124.772 157.617 1.00 22.14 ? 259 LYS A N   1 
ATOM   1278 C CA  . LYS A 1 259 ? 117.515 124.441 157.355 1.00 19.83 ? 259 LYS A CA  1 
ATOM   1279 C C   . LYS A 1 259 ? 117.248 124.158 155.881 1.00 23.14 ? 259 LYS A C   1 
ATOM   1280 O O   . LYS A 1 259 ? 116.325 123.400 155.566 1.00 28.65 ? 259 LYS A O   1 
ATOM   1281 C CB  . LYS A 1 259 ? 116.618 125.582 157.836 1.00 21.98 ? 259 LYS A CB  1 
ATOM   1282 C CG  . LYS A 1 259 ? 115.197 125.177 158.172 1.00 25.61 ? 259 LYS A CG  1 
ATOM   1283 C CD  . LYS A 1 259 ? 114.437 126.338 158.790 1.00 32.08 ? 259 LYS A CD  1 
ATOM   1284 C CE  . LYS A 1 259 ? 113.181 125.862 159.496 1.00 33.09 ? 259 LYS A CE  1 
ATOM   1285 N NZ  . LYS A 1 259 ? 112.179 125.322 158.541 1.00 30.76 ? 259 LYS A NZ  1 
ATOM   1286 N N   . SER A 1 260 ? 118.025 124.752 154.975 1.00 20.95 ? 260 SER A N   1 
ATOM   1287 C CA  . SER A 1 260 ? 117.867 124.506 153.548 1.00 14.49 ? 260 SER A CA  1 
ATOM   1288 C C   . SER A 1 260 ? 118.675 123.317 153.050 1.00 22.81 ? 260 SER A C   1 
ATOM   1289 O O   . SER A 1 260 ? 118.461 122.873 151.917 1.00 25.98 ? 260 SER A O   1 
ATOM   1290 C CB  . SER A 1 260 ? 118.262 125.751 152.751 1.00 18.62 ? 260 SER A CB  1 
ATOM   1291 O OG  . SER A 1 260 ? 117.758 125.682 151.431 1.00 26.18 ? 260 SER A OG  1 
ATOM   1292 N N   . LEU A 1 261 ? 119.599 122.802 153.855 1.00 19.28 ? 261 LEU A N   1 
ATOM   1293 C CA  . LEU A 1 261 ? 120.316 121.574 153.541 1.00 15.89 ? 261 LEU A CA  1 
ATOM   1294 C C   . LEU A 1 261 ? 119.748 120.366 154.267 1.00 21.94 ? 261 LEU A C   1 
ATOM   1295 O O   . LEU A 1 261 ? 120.513 119.484 154.669 1.00 27.49 ? 261 LEU A O   1 
ATOM   1296 C CB  . LEU A 1 261 ? 121.804 121.727 153.868 1.00 17.88 ? 261 LEU A CB  1 
ATOM   1297 C CG  . LEU A 1 261 ? 122.636 122.601 152.928 1.00 17.30 ? 261 LEU A CG  1 
ATOM   1298 C CD1 . LEU A 1 261 ? 124.110 122.455 153.235 1.00 16.28 ? 261 LEU A CD1 1 
ATOM   1299 C CD2 . LEU A 1 261 ? 122.367 122.231 151.484 1.00 14.09 ? 261 LEU A CD2 1 
ATOM   1300 N N   . GLN A 1 262 ? 118.435 120.317 154.459 1.00 30.13 ? 262 GLN A N   1 
ATOM   1301 C CA  . GLN A 1 262 ? 117.793 119.198 155.132 1.00 34.34 ? 262 GLN A CA  1 
ATOM   1302 C C   . GLN A 1 262 ? 116.614 118.684 154.314 1.00 26.19 ? 262 GLN A C   1 
ATOM   1303 O O   . GLN A 1 262 ? 116.108 119.380 153.434 1.00 24.13 ? 262 GLN A O   1 
ATOM   1304 C CB  . GLN A 1 262 ? 117.328 119.607 156.531 1.00 31.29 ? 262 GLN A CB  1 
ATOM   1305 N N   . GLN A 1 313 ? 122.358 110.992 145.150 1.00 41.82 ? 313 GLN A N   1 
ATOM   1306 C CA  . GLN A 1 313 ? 123.460 110.861 146.098 1.00 47.84 ? 313 GLN A CA  1 
ATOM   1307 C C   . GLN A 1 313 ? 123.946 112.228 146.575 1.00 51.42 ? 313 GLN A C   1 
ATOM   1308 O O   . GLN A 1 313 ? 125.053 112.360 147.100 1.00 51.49 ? 313 GLN A O   1 
ATOM   1309 C CB  . GLN A 1 313 ? 124.612 110.069 145.473 1.00 51.50 ? 313 GLN A CB  1 
ATOM   1310 C CG  . GLN A 1 313 ? 125.282 110.745 144.286 1.00 48.67 ? 313 GLN A CG  1 
ATOM   1311 C CD  . GLN A 1 313 ? 126.761 110.444 144.211 1.00 48.78 ? 313 GLN A CD  1 
ATOM   1312 O OE1 . GLN A 1 313 ? 127.163 109.333 143.867 1.00 47.49 ? 313 GLN A OE1 1 
ATOM   1313 N NE2 . GLN A 1 313 ? 127.583 111.432 144.541 1.00 49.49 ? 313 GLN A NE2 1 
ATOM   1314 N N   . SER A 1 314 ? 123.094 113.244 146.407 1.00 51.41 ? 314 SER A N   1 
ATOM   1315 C CA  . SER A 1 314 ? 123.429 114.585 146.876 1.00 48.33 ? 314 SER A CA  1 
ATOM   1316 C C   . SER A 1 314 ? 123.392 114.677 148.397 1.00 46.12 ? 314 SER A C   1 
ATOM   1317 O O   . SER A 1 314 ? 123.992 115.592 148.978 1.00 44.93 ? 314 SER A O   1 
ATOM   1318 C CB  . SER A 1 314 ? 122.474 115.605 146.261 1.00 47.66 ? 314 SER A CB  1 
ATOM   1319 O OG  . SER A 1 314 ? 121.133 115.312 146.610 1.00 47.47 ? 314 SER A OG  1 
ATOM   1320 N N   . ILE A 1 315 ? 122.695 113.742 149.052 1.00 44.30 ? 315 ILE A N   1 
ATOM   1321 C CA  . ILE A 1 315 ? 122.601 113.708 150.507 1.00 41.11 ? 315 ILE A CA  1 
ATOM   1322 C C   . ILE A 1 315 ? 123.943 113.424 151.164 1.00 40.38 ? 315 ILE A C   1 
ATOM   1323 O O   . ILE A 1 315 ? 124.147 113.787 152.324 1.00 47.39 ? 315 ILE A O   1 
ATOM   1324 C CB  . ILE A 1 315 ? 121.552 112.666 150.946 1.00 37.93 ? 315 ILE A CB  1 
ATOM   1325 N N   . SER A 1 316 ? 124.864 112.769 150.458 1.00 35.96 ? 316 SER A N   1 
ATOM   1326 C CA  . SER A 1 316 ? 126.201 112.573 151.003 1.00 35.62 ? 316 SER A CA  1 
ATOM   1327 C C   . SER A 1 316 ? 127.030 113.849 150.927 1.00 38.13 ? 316 SER A C   1 
ATOM   1328 O O   . SER A 1 316 ? 127.810 114.137 151.840 1.00 46.08 ? 316 SER A O   1 
ATOM   1329 C CB  . SER A 1 316 ? 126.906 111.435 150.269 1.00 44.47 ? 316 SER A CB  1 
ATOM   1330 O OG  . SER A 1 316 ? 127.804 111.937 149.296 1.00 44.31 ? 316 SER A OG  1 
ATOM   1331 N N   . ASN A 1 317 ? 126.880 114.623 149.847 1.00 37.69 ? 317 ASN A N   1 
ATOM   1332 C CA  . ASN A 1 317 ? 127.653 115.854 149.704 1.00 39.28 ? 317 ASN A CA  1 
ATOM   1333 C C   . ASN A 1 317 ? 127.109 116.958 150.602 1.00 35.56 ? 317 ASN A C   1 
ATOM   1334 O O   . ASN A 1 317 ? 127.859 117.846 151.034 1.00 35.33 ? 317 ASN A O   1 
ATOM   1335 C CB  . ASN A 1 317 ? 127.655 116.310 148.246 1.00 40.62 ? 317 ASN A CB  1 
ATOM   1336 C CG  . ASN A 1 317 ? 128.279 115.292 147.317 1.00 42.76 ? 317 ASN A CG  1 
ATOM   1337 O OD1 . ASN A 1 317 ? 127.585 114.475 146.714 1.00 41.77 ? 317 ASN A OD1 1 
ATOM   1338 N ND2 . ASN A 1 317 ? 129.598 115.340 147.192 1.00 43.91 ? 317 ASN A ND2 1 
ATOM   1339 N N   . GLU A 1 318 ? 125.804 116.923 150.888 1.00 33.07 ? 318 GLU A N   1 
ATOM   1340 C CA  . GLU A 1 318 ? 125.217 117.919 151.779 1.00 32.34 ? 318 GLU A CA  1 
ATOM   1341 C C   . GLU A 1 318 ? 125.726 117.776 153.208 1.00 36.67 ? 318 GLU A C   1 
ATOM   1342 O O   . GLU A 1 318 ? 125.829 118.776 153.923 1.00 44.58 ? 318 GLU A O   1 
ATOM   1343 C CB  . GLU A 1 318 ? 123.693 117.828 151.747 1.00 32.93 ? 318 GLU A CB  1 
ATOM   1344 C CG  . GLU A 1 318 ? 123.072 118.384 150.481 1.00 34.14 ? 318 GLU A CG  1 
ATOM   1345 C CD  . GLU A 1 318 ? 121.592 118.084 150.382 1.00 40.52 ? 318 GLU A CD  1 
ATOM   1346 O OE1 . GLU A 1 318 ? 121.106 117.231 151.154 1.00 40.39 ? 318 GLU A OE1 1 
ATOM   1347 O OE2 . GLU A 1 318 ? 120.915 118.698 149.533 1.00 39.20 ? 318 GLU A OE2 1 
ATOM   1348 N N   . GLN A 1 319 ? 126.077 116.558 153.633 1.00 32.94 ? 319 GLN A N   1 
ATOM   1349 C CA  . GLN A 1 319 ? 126.661 116.381 154.960 1.00 35.37 ? 319 GLN A CA  1 
ATOM   1350 C C   . GLN A 1 319 ? 128.058 116.985 155.045 1.00 38.77 ? 319 GLN A C   1 
ATOM   1351 O O   . GLN A 1 319 ? 128.414 117.587 156.065 1.00 44.25 ? 319 GLN A O   1 
ATOM   1352 C CB  . GLN A 1 319 ? 126.697 114.901 155.338 1.00 36.52 ? 319 GLN A CB  1 
ATOM   1353 C CG  . GLN A 1 319 ? 125.338 114.225 155.343 1.00 37.62 ? 319 GLN A CG  1 
ATOM   1354 C CD  . GLN A 1 319 ? 124.281 115.037 156.065 1.00 40.47 ? 319 GLN A CD  1 
ATOM   1355 O OE1 . GLN A 1 319 ? 124.429 115.366 157.242 1.00 41.29 ? 319 GLN A OE1 1 
ATOM   1356 N NE2 . GLN A 1 319 ? 123.207 115.369 155.359 1.00 36.78 ? 319 GLN A NE2 1 
ATOM   1357 N N   . LYS A 1 320 ? 128.860 116.840 153.985 1.00 28.02 ? 320 LYS A N   1 
ATOM   1358 C CA  . LYS A 1 320 ? 130.181 117.465 153.966 1.00 27.03 ? 320 LYS A CA  1 
ATOM   1359 C C   . LYS A 1 320 ? 130.071 118.984 153.923 1.00 33.80 ? 320 LYS A C   1 
ATOM   1360 O O   . LYS A 1 320 ? 130.853 119.689 154.577 1.00 34.11 ? 320 LYS A O   1 
ATOM   1361 C CB  . LYS A 1 320 ? 130.991 116.951 152.777 1.00 22.09 ? 320 LYS A CB  1 
ATOM   1362 N N   . ALA A 1 321 ? 129.089 119.502 153.176 1.00 32.42 ? 321 ALA A N   1 
ATOM   1363 C CA  . ALA A 1 321 ? 128.844 120.942 153.152 1.00 24.54 ? 321 ALA A CA  1 
ATOM   1364 C C   . ALA A 1 321 ? 128.404 121.452 154.519 1.00 27.11 ? 321 ALA A C   1 
ATOM   1365 O O   . ALA A 1 321 ? 128.839 122.521 154.962 1.00 35.61 ? 321 ALA A O   1 
ATOM   1366 C CB  . ALA A 1 321 ? 127.799 121.281 152.092 1.00 22.92 ? 321 ALA A CB  1 
ATOM   1367 N N   . CYS A 1 322 ? 127.552 120.685 155.210 1.00 23.12 ? 322 CYS A N   1 
ATOM   1368 C CA  . CYS A 1 322 ? 127.105 121.056 156.551 1.00 26.50 ? 322 CYS A CA  1 
ATOM   1369 C C   . CYS A 1 322 ? 128.256 121.042 157.549 1.00 28.30 ? 322 CYS A C   1 
ATOM   1370 O O   . CYS A 1 322 ? 128.347 121.925 158.409 1.00 36.17 ? 322 CYS A O   1 
ATOM   1371 C CB  . CYS A 1 322 ? 125.995 120.113 157.013 1.00 24.35 ? 322 CYS A CB  1 
ATOM   1372 S SG  . CYS A 1 322 ? 124.349 120.511 156.396 1.00 28.02 ? 322 CYS A SG  1 
ATOM   1373 N N   . LYS A 1 323 ? 129.144 120.048 157.446 1.00 25.06 ? 323 LYS A N   1 
ATOM   1374 C CA  . LYS A 1 323 ? 130.290 119.967 158.348 1.00 26.63 ? 323 LYS A CA  1 
ATOM   1375 C C   . LYS A 1 323 ? 131.256 121.126 158.124 1.00 27.24 ? 323 LYS A C   1 
ATOM   1376 O O   . LYS A 1 323 ? 131.769 121.712 159.086 1.00 27.93 ? 323 LYS A O   1 
ATOM   1377 C CB  . LYS A 1 323 ? 131.004 118.628 158.168 1.00 22.25 ? 323 LYS A CB  1 
ATOM   1378 N N   . VAL A 1 324 ? 131.499 121.482 156.857 1.00 24.15 ? 324 VAL A N   1 
ATOM   1379 C CA  . VAL A 1 324 ? 132.386 122.604 156.552 1.00 21.01 ? 324 VAL A CA  1 
ATOM   1380 C C   . VAL A 1 324 ? 131.774 123.923 157.020 1.00 22.36 ? 324 VAL A C   1 
ATOM   1381 O O   . VAL A 1 324 ? 132.468 124.765 157.610 1.00 39.77 ? 324 VAL A O   1 
ATOM   1382 C CB  . VAL A 1 324 ? 132.721 122.614 155.047 1.00 24.61 ? 324 VAL A CB  1 
ATOM   1383 C CG1 . VAL A 1 324 ? 133.348 123.932 154.619 1.00 23.97 ? 324 VAL A CG1 1 
ATOM   1384 C CG2 . VAL A 1 324 ? 133.662 121.467 154.720 1.00 28.73 ? 324 VAL A CG2 1 
ATOM   1385 N N   . LEU A 1 325 ? 130.461 124.103 156.810 1.00 15.91 ? 325 LEU A N   1 
ATOM   1386 C CA  . LEU A 1 325 ? 129.776 125.309 157.271 1.00 24.32 ? 325 LEU A CA  1 
ATOM   1387 C C   . LEU A 1 325 ? 129.804 125.428 158.790 1.00 27.03 ? 325 LEU A C   1 
ATOM   1388 O O   . LEU A 1 325 ? 130.037 126.519 159.326 1.00 28.74 ? 325 LEU A O   1 
ATOM   1389 C CB  . LEU A 1 325 ? 128.331 125.321 156.773 1.00 23.17 ? 325 LEU A CB  1 
ATOM   1390 C CG  . LEU A 1 325 ? 128.066 125.801 155.347 1.00 29.55 ? 325 LEU A CG  1 
ATOM   1391 C CD1 . LEU A 1 325 ? 126.648 125.463 154.927 1.00 21.76 ? 325 LEU A CD1 1 
ATOM   1392 C CD2 . LEU A 1 325 ? 128.310 127.292 155.241 1.00 33.55 ? 325 LEU A CD2 1 
ATOM   1393 N N   . GLY A 1 326 ? 129.597 124.318 159.497 1.00 23.36 ? 326 GLY A N   1 
ATOM   1394 C CA  . GLY A 1 326 ? 129.660 124.310 160.945 1.00 22.17 ? 326 GLY A CA  1 
ATOM   1395 C C   . GLY A 1 326 ? 131.034 124.628 161.496 1.00 24.23 ? 326 GLY A C   1 
ATOM   1396 O O   . GLY A 1 326 ? 131.151 125.434 162.428 1.00 27.31 ? 326 GLY A O   1 
ATOM   1397 N N   . ILE A 1 327 ? 132.073 124.019 160.906 1.00 23.43 ? 327 ILE A N   1 
ATOM   1398 C CA  . ILE A 1 327 ? 133.449 124.272 161.335 1.00 21.24 ? 327 ILE A CA  1 
ATOM   1399 C C   . ILE A 1 327 ? 133.816 125.734 161.114 1.00 18.80 ? 327 ILE A C   1 
ATOM   1400 O O   . ILE A 1 327 ? 134.354 126.393 162.011 1.00 29.87 ? 327 ILE A O   1 
ATOM   1401 C CB  . ILE A 1 327 ? 134.423 123.326 160.606 1.00 23.98 ? 327 ILE A CB  1 
ATOM   1402 C CG1 . ILE A 1 327 ? 134.326 121.911 161.173 1.00 29.17 ? 327 ILE A CG1 1 
ATOM   1403 C CG2 . ILE A 1 327 ? 135.858 123.820 160.708 1.00 16.13 ? 327 ILE A CG2 1 
ATOM   1404 C CD1 . ILE A 1 327 ? 134.884 120.850 160.250 1.00 26.50 ? 327 ILE A CD1 1 
ATOM   1405 N N   . VAL A 1 328 ? 133.460 126.277 159.944 1.00 15.79 ? 328 VAL A N   1 
ATOM   1406 C CA  . VAL A 1 328 ? 133.800 127.657 159.606 1.00 16.17 ? 328 VAL A CA  1 
ATOM   1407 C C   . VAL A 1 328 ? 133.063 128.648 160.508 1.00 23.37 ? 328 VAL A C   1 
ATOM   1408 O O   . VAL A 1 328 ? 133.675 129.582 161.049 1.00 26.18 ? 328 VAL A O   1 
ATOM   1409 C CB  . VAL A 1 328 ? 133.517 127.900 158.112 1.00 14.14 ? 328 VAL A CB  1 
ATOM   1410 C CG1 . VAL A 1 328 ? 133.324 129.369 157.816 1.00 20.66 ? 328 VAL A CG1 1 
ATOM   1411 C CG2 . VAL A 1 328 ? 134.649 127.340 157.275 1.00 14.43 ? 328 VAL A CG2 1 
ATOM   1412 N N   . PHE A 1 329 ? 131.761 128.435 160.729 1.00 22.64 ? 329 PHE A N   1 
ATOM   1413 C CA  . PHE A 1 329 ? 130.973 129.358 161.542 1.00 23.66 ? 329 PHE A CA  1 
ATOM   1414 C C   . PHE A 1 329 ? 131.407 129.335 163.004 1.00 24.80 ? 329 PHE A C   1 
ATOM   1415 O O   . PHE A 1 329 ? 131.611 130.391 163.620 1.00 24.45 ? 329 PHE A O   1 
ATOM   1416 C CB  . PHE A 1 329 ? 129.488 129.019 161.422 1.00 18.81 ? 329 PHE A CB  1 
ATOM   1417 C CG  . PHE A 1 329 ? 128.626 129.714 162.431 1.00 23.31 ? 329 PHE A CG  1 
ATOM   1418 C CD1 . PHE A 1 329 ? 128.473 131.089 162.405 1.00 28.63 ? 329 PHE A CD1 1 
ATOM   1419 C CD2 . PHE A 1 329 ? 127.969 128.990 163.411 1.00 23.30 ? 329 PHE A CD2 1 
ATOM   1420 C CE1 . PHE A 1 329 ? 127.679 131.728 163.336 1.00 23.74 ? 329 PHE A CE1 1 
ATOM   1421 C CE2 . PHE A 1 329 ? 127.174 129.624 164.344 1.00 23.37 ? 329 PHE A CE2 1 
ATOM   1422 C CZ  . PHE A 1 329 ? 127.030 130.993 164.307 1.00 21.60 ? 329 PHE A CZ  1 
ATOM   1423 N N   . PHE A 1 330 ? 131.575 128.140 163.577 1.00 25.00 ? 330 PHE A N   1 
ATOM   1424 C CA  . PHE A 1 330 ? 131.935 128.074 164.987 1.00 22.51 ? 330 PHE A CA  1 
ATOM   1425 C C   . PHE A 1 330 ? 133.384 128.471 165.219 1.00 26.35 ? 330 PHE A C   1 
ATOM   1426 O O   . PHE A 1 330 ? 133.704 129.021 166.278 1.00 31.88 ? 330 PHE A O   1 
ATOM   1427 C CB  . PHE A 1 330 ? 131.641 126.684 165.539 1.00 19.41 ? 330 PHE A CB  1 
ATOM   1428 C CG  . PHE A 1 330 ? 130.196 126.483 165.894 1.00 24.04 ? 330 PHE A CG  1 
ATOM   1429 C CD1 . PHE A 1 330 ? 129.645 127.138 166.983 1.00 26.15 ? 330 PHE A CD1 1 
ATOM   1430 C CD2 . PHE A 1 330 ? 129.384 125.667 165.125 1.00 27.42 ? 330 PHE A CD2 1 
ATOM   1431 C CE1 . PHE A 1 330 ? 128.316 126.968 167.309 1.00 21.76 ? 330 PHE A CE1 1 
ATOM   1432 C CE2 . PHE A 1 330 ? 128.054 125.492 165.445 1.00 26.76 ? 330 PHE A CE2 1 
ATOM   1433 C CZ  . PHE A 1 330 ? 127.520 126.144 166.539 1.00 28.23 ? 330 PHE A CZ  1 
ATOM   1434 N N   . LEU A 1 331 ? 134.262 128.260 164.234 1.00 23.22 ? 331 LEU A N   1 
ATOM   1435 C CA  . LEU A 1 331 ? 135.619 128.774 164.327 1.00 18.15 ? 331 LEU A CA  1 
ATOM   1436 C C   . LEU A 1 331 ? 135.663 130.294 164.258 1.00 23.66 ? 331 LEU A C   1 
ATOM   1437 O O   . LEU A 1 331 ? 136.460 130.902 164.979 1.00 31.86 ? 331 LEU A O   1 
ATOM   1438 C CB  . LEU A 1 331 ? 136.472 128.152 163.222 1.00 18.18 ? 331 LEU A CB  1 
ATOM   1439 C CG  . LEU A 1 331 ? 137.940 128.544 163.098 1.00 23.35 ? 331 LEU A CG  1 
ATOM   1440 C CD1 . LEU A 1 331 ? 138.777 127.291 162.944 1.00 29.65 ? 331 LEU A CD1 1 
ATOM   1441 C CD2 . LEU A 1 331 ? 138.139 129.465 161.906 1.00 25.74 ? 331 LEU A CD2 1 
ATOM   1442 N N   . PHE A 1 332 ? 134.819 130.916 163.425 1.00 19.29 ? 332 PHE A N   1 
ATOM   1443 C CA  . PHE A 1 332 ? 134.719 132.374 163.402 1.00 18.26 ? 332 PHE A CA  1 
ATOM   1444 C C   . PHE A 1 332 ? 134.224 132.913 164.738 1.00 21.47 ? 332 PHE A C   1 
ATOM   1445 O O   . PHE A 1 332 ? 134.756 133.906 165.254 1.00 21.29 ? 332 PHE A O   1 
ATOM   1446 C CB  . PHE A 1 332 ? 133.785 132.812 162.272 1.00 21.64 ? 332 PHE A CB  1 
ATOM   1447 C CG  . PHE A 1 332 ? 133.188 134.187 162.458 1.00 27.26 ? 332 PHE A CG  1 
ATOM   1448 C CD1 . PHE A 1 332 ? 133.949 135.318 162.221 1.00 24.62 ? 332 PHE A CD1 1 
ATOM   1449 C CD2 . PHE A 1 332 ? 131.865 134.350 162.845 1.00 28.94 ? 332 PHE A CD2 1 
ATOM   1450 C CE1 . PHE A 1 332 ? 133.413 136.583 162.375 1.00 20.32 ? 332 PHE A CE1 1 
ATOM   1451 C CE2 . PHE A 1 332 ? 131.326 135.616 163.006 1.00 30.32 ? 332 PHE A CE2 1 
ATOM   1452 C CZ  . PHE A 1 332 ? 132.102 136.731 162.768 1.00 19.83 ? 332 PHE A CZ  1 
ATOM   1453 N N   . VAL A 1 333 ? 133.203 132.261 165.306 1.00 27.61 ? 333 VAL A N   1 
ATOM   1454 C CA  . VAL A 1 333 ? 132.626 132.702 166.577 1.00 32.51 ? 333 VAL A CA  1 
ATOM   1455 C C   . VAL A 1 333 ? 133.644 132.567 167.707 1.00 30.44 ? 333 VAL A C   1 
ATOM   1456 O O   . VAL A 1 333 ? 133.827 133.488 168.512 1.00 22.70 ? 333 VAL A O   1 
ATOM   1457 C CB  . VAL A 1 333 ? 131.330 131.922 166.870 1.00 25.50 ? 333 VAL A CB  1 
ATOM   1458 C CG1 . VAL A 1 333 ? 130.892 132.097 168.312 1.00 20.61 ? 333 VAL A CG1 1 
ATOM   1459 C CG2 . VAL A 1 333 ? 130.228 132.377 165.935 1.00 26.85 ? 333 VAL A CG2 1 
ATOM   1460 N N   . VAL A 1 334 ? 134.359 131.439 167.750 1.00 31.02 ? 334 VAL A N   1 
ATOM   1461 C CA  . VAL A 1 334 ? 135.381 131.218 168.766 1.00 23.29 ? 334 VAL A CA  1 
ATOM   1462 C C   . VAL A 1 334 ? 136.573 132.161 168.599 1.00 28.16 ? 334 VAL A C   1 
ATOM   1463 O O   . VAL A 1 334 ? 137.113 132.652 169.597 1.00 29.49 ? 334 VAL A O   1 
ATOM   1464 C CB  . VAL A 1 334 ? 135.778 129.725 168.727 1.00 23.77 ? 334 VAL A CB  1 
ATOM   1465 C CG1 . VAL A 1 334 ? 137.183 129.469 169.262 1.00 25.62 ? 334 VAL A CG1 1 
ATOM   1466 C CG2 . VAL A 1 334 ? 134.764 128.900 169.497 1.00 28.62 ? 334 VAL A CG2 1 
ATOM   1467 N N   . MET A 1 335 ? 136.970 132.476 167.364 1.00 29.36 ? 335 MET A N   1 
ATOM   1468 C CA  . MET A 1 335 ? 138.139 133.325 167.161 1.00 26.92 ? 335 MET A CA  1 
ATOM   1469 C C   . MET A 1 335 ? 137.846 134.796 167.448 1.00 28.75 ? 335 MET A C   1 
ATOM   1470 O O   . MET A 1 335 ? 138.669 135.484 168.058 1.00 30.69 ? 335 MET A O   1 
ATOM   1471 C CB  . MET A 1 335 ? 138.666 133.152 165.738 1.00 25.44 ? 335 MET A CB  1 
ATOM   1472 N N   . TRP A 1 336 ? 136.684 135.302 167.024 1.00 32.65 ? 336 TRP A N   1 
ATOM   1473 C CA  . TRP A 1 336 ? 136.439 136.737 167.158 1.00 31.70 ? 336 TRP A CA  1 
ATOM   1474 C C   . TRP A 1 336 ? 135.593 137.112 168.370 1.00 39.20 ? 336 TRP A C   1 
ATOM   1475 O O   . TRP A 1 336 ? 135.735 138.220 168.895 1.00 33.91 ? 336 TRP A O   1 
ATOM   1476 C CB  . TRP A 1 336 ? 135.765 137.283 165.896 1.00 24.69 ? 336 TRP A CB  1 
ATOM   1477 C CG  . TRP A 1 336 ? 136.686 137.548 164.750 1.00 28.07 ? 336 TRP A CG  1 
ATOM   1478 C CD1 . TRP A 1 336 ? 136.660 136.948 163.531 1.00 34.42 ? 336 TRP A CD1 1 
ATOM   1479 C CD2 . TRP A 1 336 ? 137.742 138.515 164.697 1.00 32.34 ? 336 TRP A CD2 1 
ATOM   1480 N NE1 . TRP A 1 336 ? 137.645 137.460 162.727 1.00 34.40 ? 336 TRP A NE1 1 
ATOM   1481 C CE2 . TRP A 1 336 ? 138.324 138.426 163.419 1.00 33.45 ? 336 TRP A CE2 1 
ATOM   1482 C CE3 . TRP A 1 336 ? 138.259 139.440 165.610 1.00 34.77 ? 336 TRP A CE3 1 
ATOM   1483 C CZ2 . TRP A 1 336 ? 139.397 139.224 163.030 1.00 32.41 ? 336 TRP A CZ2 1 
ATOM   1484 C CZ3 . TRP A 1 336 ? 139.326 140.231 165.222 1.00 32.58 ? 336 TRP A CZ3 1 
ATOM   1485 C CH2 . TRP A 1 336 ? 139.882 140.118 163.944 1.00 34.28 ? 336 TRP A CH2 1 
ATOM   1486 N N   . CYS A 1 337 ? 134.712 136.221 168.821 1.00 42.22 ? 337 CYS A N   1 
ATOM   1487 C CA  . CYS A 1 337 ? 133.703 136.604 169.805 1.00 36.34 ? 337 CYS A CA  1 
ATOM   1488 C C   . CYS A 1 337 ? 134.194 136.885 171.231 1.00 35.79 ? 337 CYS A C   1 
ATOM   1489 O O   . CYS A 1 337 ? 133.537 137.705 171.893 1.00 38.16 ? 337 CYS A O   1 
ATOM   1490 C CB  . CYS A 1 337 ? 132.596 135.538 169.836 1.00 31.44 ? 337 CYS A CB  1 
ATOM   1491 S SG  . CYS A 1 337 ? 130.987 136.165 170.371 1.00 41.83 ? 337 CYS A SG  1 
ATOM   1492 N N   . PRO A 1 338 ? 135.236 136.233 171.795 1.00 35.12 ? 338 PRO A N   1 
ATOM   1493 C CA  . PRO A 1 338 ? 135.722 136.691 173.114 1.00 35.46 ? 338 PRO A CA  1 
ATOM   1494 C C   . PRO A 1 338 ? 136.208 138.129 173.159 1.00 36.06 ? 338 PRO A C   1 
ATOM   1495 O O   . PRO A 1 338 ? 135.923 138.835 174.140 1.00 42.16 ? 338 PRO A O   1 
ATOM   1496 C CB  . PRO A 1 338 ? 136.861 135.712 173.418 1.00 33.74 ? 338 PRO A CB  1 
ATOM   1497 C CG  . PRO A 1 338 ? 136.425 134.479 172.802 1.00 36.55 ? 338 PRO A CG  1 
ATOM   1498 C CD  . PRO A 1 338 ? 135.759 134.878 171.521 1.00 33.70 ? 338 PRO A CD  1 
ATOM   1499 N N   . PHE A 1 339 ? 136.905 138.588 172.114 1.00 32.59 ? 339 PHE A N   1 
ATOM   1500 C CA  . PHE A 1 339 ? 137.484 139.928 172.127 1.00 37.49 ? 339 PHE A CA  1 
ATOM   1501 C C   . PHE A 1 339 ? 136.405 141.002 172.118 1.00 35.43 ? 339 PHE A C   1 
ATOM   1502 O O   . PHE A 1 339 ? 136.483 141.971 172.876 1.00 40.83 ? 339 PHE A O   1 
ATOM   1503 C CB  . PHE A 1 339 ? 138.433 140.113 170.942 1.00 38.47 ? 339 PHE A CB  1 
ATOM   1504 C CG  . PHE A 1 339 ? 138.750 141.551 170.644 1.00 32.65 ? 339 PHE A CG  1 
ATOM   1505 C CD1 . PHE A 1 339 ? 139.528 142.298 171.511 1.00 25.35 ? 339 PHE A CD1 1 
ATOM   1506 C CD2 . PHE A 1 339 ? 138.263 142.157 169.497 1.00 32.23 ? 339 PHE A CD2 1 
ATOM   1507 C CE1 . PHE A 1 339 ? 139.811 143.622 171.239 1.00 26.29 ? 339 PHE A CE1 1 
ATOM   1508 C CE2 . PHE A 1 339 ? 138.542 143.479 169.225 1.00 33.84 ? 339 PHE A CE2 1 
ATOM   1509 C CZ  . PHE A 1 339 ? 139.319 144.211 170.095 1.00 31.30 ? 339 PHE A CZ  1 
ATOM   1510 N N   . PHE A 1 340 ? 135.370 140.830 171.295 1.00 21.33 ? 340 PHE A N   1 
ATOM   1511 C CA  . PHE A 1 340 ? 134.331 141.850 171.219 1.00 24.57 ? 340 PHE A CA  1 
ATOM   1512 C C   . PHE A 1 340 ? 133.427 141.836 172.444 1.00 27.42 ? 340 PHE A C   1 
ATOM   1513 O O   . PHE A 1 340 ? 132.960 142.898 172.875 1.00 33.32 ? 340 PHE A O   1 
ATOM   1514 C CB  . PHE A 1 340 ? 133.515 141.671 169.944 1.00 22.03 ? 340 PHE A CB  1 
ATOM   1515 C CG  . PHE A 1 340 ? 134.150 142.289 168.739 1.00 27.53 ? 340 PHE A CG  1 
ATOM   1516 C CD1 . PHE A 1 340 ? 133.883 143.603 168.399 1.00 26.23 ? 340 PHE A CD1 1 
ATOM   1517 C CD2 . PHE A 1 340 ? 135.033 141.564 167.958 1.00 33.71 ? 340 PHE A CD2 1 
ATOM   1518 C CE1 . PHE A 1 340 ? 134.469 144.176 167.294 1.00 26.27 ? 340 PHE A CE1 1 
ATOM   1519 C CE2 . PHE A 1 340 ? 135.626 142.133 166.852 1.00 32.15 ? 340 PHE A CE2 1 
ATOM   1520 C CZ  . PHE A 1 340 ? 135.342 143.440 166.520 1.00 29.51 ? 340 PHE A CZ  1 
ATOM   1521 N N   . ILE A 1 341 ? 133.195 140.658 173.029 1.00 28.52 ? 341 ILE A N   1 
ATOM   1522 C CA  . ILE A 1 341 ? 132.393 140.564 174.245 1.00 25.36 ? 341 ILE A CA  1 
ATOM   1523 C C   . ILE A 1 341 ? 133.104 141.249 175.406 1.00 29.94 ? 341 ILE A C   1 
ATOM   1524 O O   . ILE A 1 341 ? 132.510 142.075 176.113 1.00 33.86 ? 341 ILE A O   1 
ATOM   1525 C CB  . ILE A 1 341 ? 132.065 139.091 174.558 1.00 28.11 ? 341 ILE A CB  1 
ATOM   1526 C CG1 . ILE A 1 341 ? 130.918 138.604 173.669 1.00 31.35 ? 341 ILE A CG1 1 
ATOM   1527 C CG2 . ILE A 1 341 ? 131.722 138.888 176.029 1.00 32.83 ? 341 ILE A CG2 1 
ATOM   1528 C CD1 . ILE A 1 341 ? 129.589 139.254 173.968 1.00 31.84 ? 341 ILE A CD1 1 
ATOM   1529 N N   . THR A 1 342 ? 134.402 140.969 175.585 1.00 34.00 ? 342 THR A N   1 
ATOM   1530 C CA  . THR A 1 342 ? 135.121 141.641 176.664 1.00 33.49 ? 342 THR A CA  1 
ATOM   1531 C C   . THR A 1 342 ? 135.397 143.109 176.337 1.00 31.46 ? 342 THR A C   1 
ATOM   1532 O O   . THR A 1 342 ? 135.520 143.928 177.253 1.00 32.63 ? 342 THR A O   1 
ATOM   1533 C CB  . THR A 1 342 ? 136.411 140.886 177.009 1.00 32.13 ? 342 THR A CB  1 
ATOM   1534 O OG1 . THR A 1 342 ? 136.903 141.347 178.272 1.00 43.76 ? 342 THR A OG1 1 
ATOM   1535 C CG2 . THR A 1 342 ? 137.485 141.079 175.965 1.00 25.67 ? 342 THR A CG2 1 
ATOM   1536 N N   . ASN A 1 343 ? 135.394 143.479 175.052 1.00 28.20 ? 343 ASN A N   1 
ATOM   1537 C CA  . ASN A 1 343 ? 135.582 144.873 174.673 1.00 25.84 ? 343 ASN A CA  1 
ATOM   1538 C C   . ASN A 1 343 ? 134.351 145.707 174.999 1.00 30.81 ? 343 ASN A C   1 
ATOM   1539 O O   . ASN A 1 343 ? 134.471 146.845 175.466 1.00 34.00 ? 343 ASN A O   1 
ATOM   1540 C CB  . ASN A 1 343 ? 135.912 144.949 173.184 1.00 30.33 ? 343 ASN A CB  1 
ATOM   1541 C CG  . ASN A 1 343 ? 136.434 146.297 172.770 1.00 35.90 ? 343 ASN A CG  1 
ATOM   1542 O OD1 . ASN A 1 343 ? 137.269 146.890 173.450 1.00 41.15 ? 343 ASN A OD1 1 
ATOM   1543 N ND2 . ASN A 1 343 ? 135.960 146.785 171.632 1.00 33.73 ? 343 ASN A ND2 1 
ATOM   1544 N N   . ILE A 1 344 ? 133.158 145.163 174.748 1.00 34.16 ? 344 ILE A N   1 
ATOM   1545 C CA  . ILE A 1 344 ? 131.932 145.855 175.138 1.00 33.72 ? 344 ILE A CA  1 
ATOM   1546 C C   . ILE A 1 344 ? 131.773 145.850 176.657 1.00 34.34 ? 344 ILE A C   1 
ATOM   1547 O O   . ILE A 1 344 ? 131.377 146.860 177.255 1.00 36.17 ? 344 ILE A O   1 
ATOM   1548 C CB  . ILE A 1 344 ? 130.721 145.242 174.404 1.00 29.78 ? 344 ILE A CB  1 
ATOM   1549 C CG1 . ILE A 1 344 ? 130.623 145.843 172.997 1.00 31.65 ? 344 ILE A CG1 1 
ATOM   1550 C CG2 . ILE A 1 344 ? 129.414 145.418 175.181 1.00 29.92 ? 344 ILE A CG2 1 
ATOM   1551 C CD1 . ILE A 1 344 ? 129.307 145.600 172.288 1.00 33.28 ? 344 ILE A CD1 1 
ATOM   1552 N N   . MET A 1 345 ? 132.137 144.739 177.312 1.00 32.12 ? 345 MET A N   1 
ATOM   1553 C CA  . MET A 1 345 ? 132.020 144.663 178.767 1.00 30.59 ? 345 MET A CA  1 
ATOM   1554 C C   . MET A 1 345 ? 133.026 145.573 179.468 1.00 31.66 ? 345 MET A C   1 
ATOM   1555 O O   . MET A 1 345 ? 132.848 145.911 180.643 1.00 34.91 ? 345 MET A O   1 
ATOM   1556 C CB  . MET A 1 345 ? 132.191 143.218 179.231 1.00 30.55 ? 345 MET A CB  1 
ATOM   1557 N N   . ALA A 1 346 ? 134.102 145.958 178.774 1.00 34.92 ? 346 ALA A N   1 
ATOM   1558 C CA  . ALA A 1 346 ? 135.000 146.978 179.306 1.00 37.85 ? 346 ALA A CA  1 
ATOM   1559 C C   . ALA A 1 346 ? 134.307 148.330 179.414 1.00 35.05 ? 346 ALA A C   1 
ATOM   1560 O O   . ALA A 1 346 ? 134.472 149.042 180.411 1.00 35.42 ? 346 ALA A O   1 
ATOM   1561 C CB  . ALA A 1 346 ? 136.245 147.090 178.428 1.00 38.01 ? 346 ALA A CB  1 
ATOM   1562 N N   . VAL A 1 347 ? 133.528 148.702 178.398 1.00 37.06 ? 347 VAL A N   1 
ATOM   1563 C CA  . VAL A 1 347 ? 132.862 150.000 178.422 1.00 38.88 ? 347 VAL A CA  1 
ATOM   1564 C C   . VAL A 1 347 ? 131.601 149.954 179.275 1.00 37.46 ? 347 VAL A C   1 
ATOM   1565 O O   . VAL A 1 347 ? 131.170 150.986 179.802 1.00 40.51 ? 347 VAL A O   1 
ATOM   1566 C CB  . VAL A 1 347 ? 132.550 150.470 176.992 1.00 32.08 ? 347 VAL A CB  1 
ATOM   1567 N N   . ILE A 1 348 ? 130.981 148.781 179.410 1.00 32.33 ? 348 ILE A N   1 
ATOM   1568 C CA  . ILE A 1 348 ? 129.807 148.656 180.269 1.00 33.04 ? 348 ILE A CA  1 
ATOM   1569 C C   . ILE A 1 348 ? 130.202 148.762 181.737 1.00 39.79 ? 348 ILE A C   1 
ATOM   1570 O O   . ILE A 1 348 ? 129.499 149.388 182.539 1.00 42.52 ? 348 ILE A O   1 
ATOM   1571 C CB  . ILE A 1 348 ? 129.065 147.341 179.976 1.00 35.74 ? 348 ILE A CB  1 
ATOM   1572 N N   . CYS A 1 349 ? 131.325 148.158 182.113 1.00 39.44 ? 349 CYS A N   1 
ATOM   1573 C CA  . CYS A 1 349 ? 131.800 148.209 183.491 1.00 37.79 ? 349 CYS A CA  1 
ATOM   1574 C C   . CYS A 1 349 ? 132.507 149.528 183.785 1.00 40.68 ? 349 CYS A C   1 
ATOM   1575 O O   . CYS A 1 349 ? 133.157 149.678 184.819 1.00 40.35 ? 349 CYS A O   1 
ATOM   1576 C CB  . CYS A 1 349 ? 132.740 147.038 183.780 1.00 33.26 ? 349 CYS A CB  1 
ATOM   1577 S SG  . CYS A 1 349 ? 131.926 145.428 183.819 1.00 42.04 ? 349 CYS A SG  1 
ATOM   1578 N N   . ASP A 1 356 ? 142.311 145.182 186.592 1.00 45.65 ? 356 ASP A N   1 
ATOM   1579 C CA  . ASP A 1 356 ? 143.185 145.056 185.434 1.00 44.29 ? 356 ASP A CA  1 
ATOM   1580 C C   . ASP A 1 356 ? 143.053 143.678 184.799 1.00 48.88 ? 356 ASP A C   1 
ATOM   1581 O O   . ASP A 1 356 ? 143.892 143.274 183.997 1.00 51.83 ? 356 ASP A O   1 
ATOM   1582 C CB  . ASP A 1 356 ? 144.639 145.316 185.827 1.00 43.33 ? 356 ASP A CB  1 
ATOM   1583 N N   . VAL A 1 357 ? 142.001 142.951 185.181 1.00 47.17 ? 357 VAL A N   1 
ATOM   1584 C CA  . VAL A 1 357 ? 141.737 141.648 184.577 1.00 44.45 ? 357 VAL A CA  1 
ATOM   1585 C C   . VAL A 1 357 ? 141.245 141.813 183.146 1.00 43.82 ? 357 VAL A C   1 
ATOM   1586 O O   . VAL A 1 357 ? 141.549 140.991 182.271 1.00 42.17 ? 357 VAL A O   1 
ATOM   1587 C CB  . VAL A 1 357 ? 140.732 140.855 185.432 1.00 44.33 ? 357 VAL A CB  1 
ATOM   1588 N N   . ILE A 1 358 ? 140.471 142.873 182.892 1.00 46.73 ? 358 ILE A N   1 
ATOM   1589 C CA  . ILE A 1 358 ? 139.898 143.107 181.567 1.00 47.07 ? 358 ILE A CA  1 
ATOM   1590 C C   . ILE A 1 358 ? 140.996 143.416 180.554 1.00 50.70 ? 358 ILE A C   1 
ATOM   1591 O O   . ILE A 1 358 ? 140.990 142.898 179.431 1.00 55.23 ? 358 ILE A O   1 
ATOM   1592 C CB  . ILE A 1 358 ? 138.851 144.235 181.635 1.00 48.84 ? 358 ILE A CB  1 
ATOM   1593 C CG1 . ILE A 1 358 ? 137.691 143.835 182.552 1.00 50.56 ? 358 ILE A CG1 1 
ATOM   1594 C CG2 . ILE A 1 358 ? 138.333 144.592 180.251 1.00 46.38 ? 358 ILE A CG2 1 
ATOM   1595 C CD1 . ILE A 1 358 ? 136.754 142.797 181.959 1.00 48.91 ? 358 ILE A CD1 1 
ATOM   1596 N N   . GLY A 1 359 ? 141.969 144.245 180.947 1.00 42.71 ? 359 GLY A N   1 
ATOM   1597 C CA  . GLY A 1 359 ? 143.082 144.551 180.061 1.00 43.54 ? 359 GLY A CA  1 
ATOM   1598 C C   . GLY A 1 359 ? 143.979 143.360 179.783 1.00 46.76 ? 359 GLY A C   1 
ATOM   1599 O O   . GLY A 1 359 ? 144.440 143.174 178.651 1.00 49.78 ? 359 GLY A O   1 
ATOM   1600 N N   . ALA A 1 360 ? 144.219 142.526 180.797 1.00 46.06 ? 360 ALA A N   1 
ATOM   1601 C CA  . ALA A 1 360 ? 145.015 141.320 180.598 1.00 48.60 ? 360 ALA A CA  1 
ATOM   1602 C C   . ALA A 1 360 ? 144.284 140.293 179.744 1.00 48.42 ? 360 ALA A C   1 
ATOM   1603 O O   . ALA A 1 360 ? 144.928 139.514 179.034 1.00 43.61 ? 360 ALA A O   1 
ATOM   1604 C CB  . ALA A 1 360 ? 145.397 140.713 181.946 1.00 48.41 ? 360 ALA A CB  1 
ATOM   1605 N N   . LEU A 1 361 ? 142.949 140.262 179.808 1.00 42.88 ? 361 LEU A N   1 
ATOM   1606 C CA  . LEU A 1 361 ? 142.192 139.409 178.898 1.00 37.38 ? 361 LEU A CA  1 
ATOM   1607 C C   . LEU A 1 361 ? 142.232 139.952 177.476 1.00 41.05 ? 361 LEU A C   1 
ATOM   1608 O O   . LEU A 1 361 ? 142.363 139.185 176.515 1.00 48.90 ? 361 LEU A O   1 
ATOM   1609 C CB  . LEU A 1 361 ? 140.747 139.269 179.374 1.00 36.52 ? 361 LEU A CB  1 
ATOM   1610 C CG  . LEU A 1 361 ? 140.489 138.326 180.547 1.00 43.55 ? 361 LEU A CG  1 
ATOM   1611 C CD1 . LEU A 1 361 ? 139.000 138.155 180.767 1.00 44.79 ? 361 LEU A CD1 1 
ATOM   1612 C CD2 . LEU A 1 361 ? 141.156 136.983 180.317 1.00 42.34 ? 361 LEU A CD2 1 
ATOM   1613 N N   . LEU A 1 362 ? 142.118 141.277 177.328 1.00 32.06 ? 362 LEU A N   1 
ATOM   1614 C CA  . LEU A 1 362 ? 142.122 141.909 176.010 1.00 31.83 ? 362 LEU A CA  1 
ATOM   1615 C C   . LEU A 1 362 ? 143.458 141.736 175.308 1.00 34.03 ? 362 LEU A C   1 
ATOM   1616 O O   . LEU A 1 362 ? 143.508 141.580 174.082 1.00 38.46 ? 362 LEU A O   1 
ATOM   1617 C CB  . LEU A 1 362 ? 141.798 143.396 176.146 1.00 31.16 ? 362 LEU A CB  1 
ATOM   1618 C CG  . LEU A 1 362 ? 140.336 143.807 176.246 1.00 37.26 ? 362 LEU A CG  1 
ATOM   1619 C CD1 . LEU A 1 362 ? 140.227 145.178 176.877 1.00 37.84 ? 362 LEU A CD1 1 
ATOM   1620 C CD2 . LEU A 1 362 ? 139.734 143.822 174.866 1.00 39.82 ? 362 LEU A CD2 1 
ATOM   1621 N N   . ASN A 1 363 ? 144.549 141.741 176.081 1.00 34.85 ? 363 ASN A N   1 
ATOM   1622 C CA  . ASN A 1 363 ? 145.894 141.663 175.525 1.00 37.20 ? 363 ASN A CA  1 
ATOM   1623 C C   . ASN A 1 363 ? 146.140 140.326 174.824 1.00 39.94 ? 363 ASN A C   1 
ATOM   1624 O O   . ASN A 1 363 ? 146.890 140.278 173.845 1.00 41.97 ? 363 ASN A O   1 
ATOM   1625 C CB  . ASN A 1 363 ? 146.897 141.898 176.664 1.00 41.51 ? 363 ASN A CB  1 
ATOM   1626 C CG  . ASN A 1 363 ? 148.286 142.302 176.183 1.00 41.60 ? 363 ASN A CG  1 
ATOM   1627 O OD1 . ASN A 1 363 ? 148.679 142.051 175.051 1.00 41.78 ? 363 ASN A OD1 1 
ATOM   1628 N ND2 . ASN A 1 363 ? 149.040 142.937 177.070 1.00 40.92 ? 363 ASN A ND2 1 
ATOM   1629 N N   . VAL A 1 364 ? 145.485 139.255 175.258 1.00 34.63 ? 364 VAL A N   1 
ATOM   1630 C CA  . VAL A 1 364 ? 145.605 137.957 174.599 1.00 34.02 ? 364 VAL A CA  1 
ATOM   1631 C C   . VAL A 1 364 ? 144.434 137.690 173.657 1.00 34.85 ? 364 VAL A C   1 
ATOM   1632 O O   . VAL A 1 364 ? 144.571 136.943 172.688 1.00 38.22 ? 364 VAL A O   1 
ATOM   1633 C CB  . VAL A 1 364 ? 145.780 136.827 175.641 1.00 36.60 ? 364 VAL A CB  1 
ATOM   1634 C CG1 . VAL A 1 364 ? 146.851 137.204 176.647 1.00 39.33 ? 364 VAL A CG1 1 
ATOM   1635 C CG2 . VAL A 1 364 ? 144.480 136.511 176.365 1.00 39.28 ? 364 VAL A CG2 1 
ATOM   1636 N N   . PHE A 1 365 ? 143.280 138.327 173.887 1.00 31.64 ? 365 PHE A N   1 
ATOM   1637 C CA  . PHE A 1 365 ? 142.156 138.127 172.981 1.00 28.76 ? 365 PHE A CA  1 
ATOM   1638 C C   . PHE A 1 365 ? 142.340 138.874 171.669 1.00 34.38 ? 365 PHE A C   1 
ATOM   1639 O O   . PHE A 1 365 ? 141.737 138.487 170.662 1.00 34.80 ? 365 PHE A O   1 
ATOM   1640 C CB  . PHE A 1 365 ? 140.846 138.548 173.649 1.00 31.75 ? 365 PHE A CB  1 
ATOM   1641 C CG  . PHE A 1 365 ? 140.360 137.588 174.702 1.00 34.70 ? 365 PHE A CG  1 
ATOM   1642 C CD1 . PHE A 1 365 ? 140.870 136.301 174.786 1.00 30.64 ? 365 PHE A CD1 1 
ATOM   1643 C CD2 . PHE A 1 365 ? 139.386 137.976 175.608 1.00 37.54 ? 365 PHE A CD2 1 
ATOM   1644 C CE1 . PHE A 1 365 ? 140.420 135.423 175.755 1.00 34.40 ? 365 PHE A CE1 1 
ATOM   1645 C CE2 . PHE A 1 365 ? 138.932 137.103 176.579 1.00 36.17 ? 365 PHE A CE2 1 
ATOM   1646 C CZ  . PHE A 1 365 ? 139.449 135.826 176.651 1.00 37.61 ? 365 PHE A CZ  1 
ATOM   1647 N N   . VAL A 1 366 ? 143.158 139.933 171.661 1.00 35.00 ? 366 VAL A N   1 
ATOM   1648 C CA  . VAL A 1 366 ? 143.543 140.574 170.405 1.00 28.39 ? 366 VAL A CA  1 
ATOM   1649 C C   . VAL A 1 366 ? 144.342 139.605 169.540 1.00 34.59 ? 366 VAL A C   1 
ATOM   1650 O O   . VAL A 1 366 ? 144.079 139.459 168.339 1.00 38.31 ? 366 VAL A O   1 
ATOM   1651 C CB  . VAL A 1 366 ? 144.323 141.872 170.691 1.00 27.53 ? 366 VAL A CB  1 
ATOM   1652 C CG1 . VAL A 1 366 ? 145.122 142.315 169.485 1.00 33.37 ? 366 VAL A CG1 1 
ATOM   1653 C CG2 . VAL A 1 366 ? 143.373 142.972 171.094 1.00 34.85 ? 366 VAL A CG2 1 
ATOM   1654 N N   . TRP A 1 367 ? 145.298 138.895 170.143 1.00 36.22 ? 367 TRP A N   1 
ATOM   1655 C CA  . TRP A 1 367 ? 146.102 137.943 169.383 1.00 33.03 ? 367 TRP A CA  1 
ATOM   1656 C C   . TRP A 1 367 ? 145.314 136.689 169.026 1.00 33.16 ? 367 TRP A C   1 
ATOM   1657 O O   . TRP A 1 367 ? 145.643 136.019 168.041 1.00 37.39 ? 367 TRP A O   1 
ATOM   1658 C CB  . TRP A 1 367 ? 147.360 137.579 170.163 1.00 35.01 ? 367 TRP A CB  1 
ATOM   1659 C CG  . TRP A 1 367 ? 148.433 138.599 170.037 1.00 37.98 ? 367 TRP A CG  1 
ATOM   1660 C CD1 . TRP A 1 367 ? 148.733 139.585 170.925 1.00 40.91 ? 367 TRP A CD1 1 
ATOM   1661 C CD2 . TRP A 1 367 ? 149.352 138.742 168.952 1.00 37.54 ? 367 TRP A CD2 1 
ATOM   1662 N NE1 . TRP A 1 367 ? 149.786 140.334 170.463 1.00 43.12 ? 367 TRP A NE1 1 
ATOM   1663 C CE2 . TRP A 1 367 ? 150.184 139.836 169.252 1.00 41.71 ? 367 TRP A CE2 1 
ATOM   1664 C CE3 . TRP A 1 367 ? 149.554 138.050 167.755 1.00 34.45 ? 367 TRP A CE3 1 
ATOM   1665 C CZ2 . TRP A 1 367 ? 151.203 140.253 168.400 1.00 34.67 ? 367 TRP A CZ2 1 
ATOM   1666 C CZ3 . TRP A 1 367 ? 150.564 138.466 166.913 1.00 37.69 ? 367 TRP A CZ3 1 
ATOM   1667 C CH2 . TRP A 1 367 ? 151.375 139.557 167.238 1.00 33.70 ? 367 TRP A CH2 1 
ATOM   1668 N N   . ILE A 1 368 ? 144.300 136.339 169.822 1.00 35.21 ? 368 ILE A N   1 
ATOM   1669 C CA  . ILE A 1 368 ? 143.355 135.304 169.401 1.00 35.39 ? 368 ILE A CA  1 
ATOM   1670 C C   . ILE A 1 368 ? 142.576 135.773 168.178 1.00 32.63 ? 368 ILE A C   1 
ATOM   1671 O O   . ILE A 1 368 ? 142.362 135.009 167.228 1.00 34.70 ? 368 ILE A O   1 
ATOM   1672 C CB  . ILE A 1 368 ? 142.429 134.908 170.571 1.00 36.96 ? 368 ILE A CB  1 
ATOM   1673 C CG1 . ILE A 1 368 ? 143.219 134.160 171.645 1.00 35.37 ? 368 ILE A CG1 1 
ATOM   1674 C CG2 . ILE A 1 368 ? 141.269 134.041 170.112 1.00 29.77 ? 368 ILE A CG2 1 
ATOM   1675 C CD1 . ILE A 1 368 ? 143.894 132.909 171.145 1.00 32.15 ? 368 ILE A CD1 1 
ATOM   1676 N N   . GLY A 1 369 ? 142.175 137.044 168.164 1.00 30.23 ? 369 GLY A N   1 
ATOM   1677 C CA  . GLY A 1 369 ? 141.550 137.644 167.000 1.00 30.33 ? 369 GLY A CA  1 
ATOM   1678 C C   . GLY A 1 369 ? 142.450 137.712 165.780 1.00 34.45 ? 369 GLY A C   1 
ATOM   1679 O O   . GLY A 1 369 ? 141.974 137.607 164.647 1.00 37.51 ? 369 GLY A O   1 
ATOM   1680 N N   . TYR A 1 370 ? 143.756 137.887 165.998 1.00 38.30 ? 370 TYR A N   1 
ATOM   1681 C CA  . TYR A 1 370 ? 144.699 137.883 164.882 1.00 34.23 ? 370 TYR A CA  1 
ATOM   1682 C C   . TYR A 1 370 ? 144.916 136.475 164.344 1.00 35.84 ? 370 TYR A C   1 
ATOM   1683 O O   . TYR A 1 370 ? 145.346 136.302 163.199 1.00 39.57 ? 370 TYR A O   1 
ATOM   1684 C CB  . TYR A 1 370 ? 146.037 138.486 165.309 1.00 33.70 ? 370 TYR A CB  1 
ATOM   1685 C CG  . TYR A 1 370 ? 146.036 139.982 165.520 1.00 34.15 ? 370 TYR A CG  1 
ATOM   1686 C CD1 . TYR A 1 370 ? 145.008 140.777 165.034 1.00 31.87 ? 370 TYR A CD1 1 
ATOM   1687 C CD2 . TYR A 1 370 ? 147.077 140.599 166.200 1.00 38.51 ? 370 TYR A CD2 1 
ATOM   1688 C CE1 . TYR A 1 370 ? 145.016 142.142 165.228 1.00 33.54 ? 370 TYR A CE1 1 
ATOM   1689 C CE2 . TYR A 1 370 ? 147.092 141.959 166.398 1.00 34.26 ? 370 TYR A CE2 1 
ATOM   1690 C CZ  . TYR A 1 370 ? 146.062 142.723 165.912 1.00 35.31 ? 370 TYR A CZ  1 
ATOM   1691 O OH  . TYR A 1 370 ? 146.080 144.079 166.112 1.00 43.57 ? 370 TYR A OH  1 
ATOM   1692 N N   . LEU A 1 371 ? 144.639 135.456 165.161 1.00 38.32 ? 371 LEU A N   1 
ATOM   1693 C CA  . LEU A 1 371 ? 144.817 134.076 164.719 1.00 35.34 ? 371 LEU A CA  1 
ATOM   1694 C C   . LEU A 1 371 ? 143.767 133.667 163.698 1.00 33.90 ? 371 LEU A C   1 
ATOM   1695 O O   . LEU A 1 371 ? 143.970 132.694 162.967 1.00 38.50 ? 371 LEU A O   1 
ATOM   1696 C CB  . LEU A 1 371 ? 144.778 133.128 165.917 1.00 37.20 ? 371 LEU A CB  1 
ATOM   1697 C CG  . LEU A 1 371 ? 145.616 131.851 165.837 1.00 37.13 ? 371 LEU A CG  1 
ATOM   1698 C CD1 . LEU A 1 371 ? 147.054 132.160 165.495 1.00 35.58 ? 371 LEU A CD1 1 
ATOM   1699 C CD2 . LEU A 1 371 ? 145.534 131.089 167.148 1.00 35.76 ? 371 LEU A CD2 1 
ATOM   1700 N N   . SER A 1 372 ? 142.641 134.384 163.642 1.00 31.78 ? 372 SER A N   1 
ATOM   1701 C CA  . SER A 1 372 ? 141.614 134.088 162.648 1.00 32.15 ? 372 SER A CA  1 
ATOM   1702 C C   . SER A 1 372 ? 142.109 134.383 161.239 1.00 36.33 ? 372 SER A C   1 
ATOM   1703 O O   . SER A 1 372 ? 141.764 133.671 160.291 1.00 37.81 ? 372 SER A O   1 
ATOM   1704 C CB  . SER A 1 372 ? 140.351 134.892 162.946 1.00 31.88 ? 372 SER A CB  1 
ATOM   1705 O OG  . SER A 1 372 ? 139.238 134.368 162.248 1.00 30.84 ? 372 SER A OG  1 
ATOM   1706 N N   . SER A 1 373 ? 142.942 135.413 161.088 1.00 37.25 ? 373 SER A N   1 
ATOM   1707 C CA  . SER A 1 373 ? 143.443 135.814 159.780 1.00 35.44 ? 373 SER A CA  1 
ATOM   1708 C C   . SER A 1 373 ? 144.478 134.854 159.211 1.00 38.05 ? 373 SER A C   1 
ATOM   1709 O O   . SER A 1 373 ? 144.799 134.957 158.023 1.00 41.63 ? 373 SER A O   1 
ATOM   1710 C CB  . SER A 1 373 ? 144.032 137.217 159.868 1.00 35.34 ? 373 SER A CB  1 
ATOM   1711 O OG  . SER A 1 373 ? 143.015 138.165 160.138 1.00 39.80 ? 373 SER A OG  1 
ATOM   1712 N N   . ALA A 1 374 ? 145.016 133.940 160.020 1.00 36.91 ? 374 ALA A N   1 
ATOM   1713 C CA  . ALA A 1 374 ? 145.883 132.897 159.487 1.00 37.10 ? 374 ALA A CA  1 
ATOM   1714 C C   . ALA A 1 374 ? 145.105 131.620 159.198 1.00 37.33 ? 374 ALA A C   1 
ATOM   1715 O O   . ALA A 1 374 ? 145.538 130.797 158.386 1.00 37.90 ? 374 ALA A O   1 
ATOM   1716 C CB  . ALA A 1 374 ? 147.025 132.610 160.460 1.00 36.40 ? 374 ALA A CB  1 
ATOM   1717 N N   . VAL A 1 375 ? 143.959 131.440 159.855 1.00 32.75 ? 375 VAL A N   1 
ATOM   1718 C CA  . VAL A 1 375 ? 143.175 130.224 159.674 1.00 25.66 ? 375 VAL A CA  1 
ATOM   1719 C C   . VAL A 1 375 ? 142.179 130.380 158.526 1.00 27.55 ? 375 VAL A C   1 
ATOM   1720 O O   . VAL A 1 375 ? 141.907 129.408 157.808 1.00 45.70 ? 375 VAL A O   1 
ATOM   1721 C CB  . VAL A 1 375 ? 142.502 129.851 161.010 1.00 26.39 ? 375 VAL A CB  1 
ATOM   1722 C CG1 . VAL A 1 375 ? 141.618 128.633 160.883 1.00 29.43 ? 375 VAL A CG1 1 
ATOM   1723 C CG2 . VAL A 1 375 ? 143.558 129.568 162.055 1.00 32.22 ? 375 VAL A CG2 1 
ATOM   1724 N N   . ASN A 1 376 ? 141.673 131.599 158.300 1.00 25.69 ? 376 ASN A N   1 
ATOM   1725 C CA  . ASN A 1 376 ? 140.713 131.877 157.226 1.00 34.85 ? 376 ASN A CA  1 
ATOM   1726 C C   . ASN A 1 376 ? 141.179 131.497 155.818 1.00 40.43 ? 376 ASN A C   1 
ATOM   1727 O O   . ASN A 1 376 ? 140.328 131.083 155.017 1.00 38.74 ? 376 ASN A O   1 
ATOM   1728 C CB  . ASN A 1 376 ? 140.281 133.352 157.274 1.00 32.00 ? 376 ASN A CB  1 
ATOM   1729 C CG  . ASN A 1 376 ? 139.309 133.644 158.397 1.00 42.72 ? 376 ASN A CG  1 
ATOM   1730 O OD1 . ASN A 1 376 ? 138.620 132.750 158.888 1.00 49.65 ? 376 ASN A OD1 1 
ATOM   1731 N ND2 . ASN A 1 376 ? 139.240 134.906 158.804 1.00 34.41 ? 376 ASN A ND2 1 
ATOM   1732 N N   . PRO A 1 377 ? 142.456 131.641 155.423 1.00 38.88 ? 377 PRO A N   1 
ATOM   1733 C CA  . PRO A 1 377 ? 142.881 130.969 154.182 1.00 31.37 ? 377 PRO A CA  1 
ATOM   1734 C C   . PRO A 1 377 ? 142.787 129.454 154.216 1.00 33.36 ? 377 PRO A C   1 
ATOM   1735 O O   . PRO A 1 377 ? 142.520 128.840 153.179 1.00 38.06 ? 377 PRO A O   1 
ATOM   1736 C CB  . PRO A 1 377 ? 144.330 131.426 154.029 1.00 33.77 ? 377 PRO A CB  1 
ATOM   1737 C CG  . PRO A 1 377 ? 144.333 132.733 154.603 1.00 39.55 ? 377 PRO A CG  1 
ATOM   1738 C CD  . PRO A 1 377 ? 143.456 132.660 155.801 1.00 38.36 ? 377 PRO A CD  1 
ATOM   1739 N N   . LEU A 1 378 ? 143.011 128.827 155.370 1.00 29.71 ? 378 LEU A N   1 
ATOM   1740 C CA  . LEU A 1 378 ? 143.046 127.370 155.416 1.00 27.80 ? 378 LEU A CA  1 
ATOM   1741 C C   . LEU A 1 378 ? 141.644 126.778 155.363 1.00 25.19 ? 378 LEU A C   1 
ATOM   1742 O O   . LEU A 1 378 ? 141.359 125.899 154.545 1.00 34.16 ? 378 LEU A O   1 
ATOM   1743 C CB  . LEU A 1 378 ? 143.792 126.900 156.665 1.00 28.85 ? 378 LEU A CB  1 
ATOM   1744 C CG  . LEU A 1 378 ? 145.203 127.461 156.838 1.00 30.73 ? 378 LEU A CG  1 
ATOM   1745 C CD1 . LEU A 1 378 ? 145.854 126.895 158.085 1.00 34.68 ? 378 LEU A CD1 1 
ATOM   1746 C CD2 . LEU A 1 378 ? 146.049 127.165 155.614 1.00 30.83 ? 378 LEU A CD2 1 
ATOM   1747 N N   . VAL A 1 379 ? 140.741 127.263 156.217 1.00 21.05 ? 379 VAL A N   1 
ATOM   1748 C CA  . VAL A 1 379 ? 139.426 126.640 156.316 1.00 23.46 ? 379 VAL A CA  1 
ATOM   1749 C C   . VAL A 1 379 ? 138.512 127.014 155.153 1.00 28.08 ? 379 VAL A C   1 
ATOM   1750 O O   . VAL A 1 379 ? 137.445 126.411 154.994 1.00 34.65 ? 379 VAL A O   1 
ATOM   1751 C CB  . VAL A 1 379 ? 138.767 126.990 157.661 1.00 30.74 ? 379 VAL A CB  1 
ATOM   1752 C CG1 . VAL A 1 379 ? 139.513 126.316 158.799 1.00 29.33 ? 379 VAL A CG1 1 
ATOM   1753 C CG2 . VAL A 1 379 ? 138.720 128.493 157.858 1.00 37.17 ? 379 VAL A CG2 1 
ATOM   1754 N N   . TYR A 1 380 ? 138.895 127.991 154.332 1.00 28.89 ? 380 TYR A N   1 
ATOM   1755 C CA  . TYR A 1 380 ? 138.096 128.358 153.170 1.00 35.89 ? 380 TYR A CA  1 
ATOM   1756 C C   . TYR A 1 380 ? 138.642 127.804 151.860 1.00 39.99 ? 380 TYR A C   1 
ATOM   1757 O O   . TYR A 1 380 ? 137.977 127.949 150.829 1.00 41.85 ? 380 TYR A O   1 
ATOM   1758 C CB  . TYR A 1 380 ? 137.986 129.881 153.065 1.00 34.47 ? 380 TYR A CB  1 
ATOM   1759 C CG  . TYR A 1 380 ? 136.902 130.490 153.924 1.00 38.62 ? 380 TYR A CG  1 
ATOM   1760 C CD1 . TYR A 1 380 ? 135.601 130.595 153.453 1.00 41.62 ? 380 TYR A CD1 1 
ATOM   1761 C CD2 . TYR A 1 380 ? 137.180 130.977 155.194 1.00 29.51 ? 380 TYR A CD2 1 
ATOM   1762 C CE1 . TYR A 1 380 ? 134.604 131.155 154.227 1.00 35.94 ? 380 TYR A CE1 1 
ATOM   1763 C CE2 . TYR A 1 380 ? 136.190 131.538 155.975 1.00 27.54 ? 380 TYR A CE2 1 
ATOM   1764 C CZ  . TYR A 1 380 ? 134.905 131.625 155.484 1.00 31.31 ? 380 TYR A CZ  1 
ATOM   1765 O OH  . TYR A 1 380 ? 133.911 132.185 156.249 1.00 27.78 ? 380 TYR A OH  1 
ATOM   1766 N N   . THR A 1 381 ? 139.824 127.189 151.861 1.00 43.75 ? 381 THR A N   1 
ATOM   1767 C CA  . THR A 1 381 ? 140.413 126.671 150.628 1.00 37.79 ? 381 THR A CA  1 
ATOM   1768 C C   . THR A 1 381 ? 140.715 125.181 150.675 1.00 41.02 ? 381 THR A C   1 
ATOM   1769 O O   . THR A 1 381 ? 140.597 124.511 149.648 1.00 48.80 ? 381 THR A O   1 
ATOM   1770 C CB  . THR A 1 381 ? 141.709 127.415 150.281 1.00 38.88 ? 381 THR A CB  1 
ATOM   1771 O OG1 . THR A 1 381 ? 142.654 127.252 151.344 1.00 42.27 ? 381 THR A OG1 1 
ATOM   1772 C CG2 . THR A 1 381 ? 141.449 128.888 150.051 1.00 40.43 ? 381 THR A CG2 1 
ATOM   1773 N N   . LEU A 1 382 ? 141.102 124.644 151.835 1.00 37.33 ? 382 LEU A N   1 
ATOM   1774 C CA  . LEU A 1 382 ? 141.562 123.261 151.908 1.00 37.90 ? 382 LEU A CA  1 
ATOM   1775 C C   . LEU A 1 382 ? 140.440 122.239 151.776 1.00 41.17 ? 382 LEU A C   1 
ATOM   1776 O O   . LEU A 1 382 ? 140.732 121.047 151.642 1.00 41.90 ? 382 LEU A O   1 
ATOM   1777 C CB  . LEU A 1 382 ? 142.321 123.022 153.212 1.00 39.38 ? 382 LEU A CB  1 
ATOM   1778 C CG  . LEU A 1 382 ? 143.645 123.772 153.365 1.00 41.82 ? 382 LEU A CG  1 
ATOM   1779 C CD1 . LEU A 1 382 ? 144.319 123.400 154.672 1.00 40.95 ? 382 LEU A CD1 1 
ATOM   1780 C CD2 . LEU A 1 382 ? 144.563 123.506 152.187 1.00 39.16 ? 382 LEU A CD2 1 
ATOM   1781 N N   . PHE A 1 383 ? 139.175 122.665 151.803 1.00 43.79 ? 383 PHE A N   1 
ATOM   1782 C CA  . PHE A 1 383 ? 138.082 121.754 151.482 1.00 46.51 ? 383 PHE A CA  1 
ATOM   1783 C C   . PHE A 1 383 ? 138.033 121.418 149.997 1.00 49.35 ? 383 PHE A C   1 
ATOM   1784 O O   . PHE A 1 383 ? 137.391 120.434 149.615 1.00 50.69 ? 383 PHE A O   1 
ATOM   1785 C CB  . PHE A 1 383 ? 136.748 122.354 151.926 1.00 47.73 ? 383 PHE A CB  1 
ATOM   1786 N N   . ASN A 1 384 ? 138.692 122.212 149.156 1.00 55.56 ? 384 ASN A N   1 
ATOM   1787 C CA  . ASN A 1 384 ? 138.765 121.982 147.719 1.00 54.55 ? 384 ASN A CA  1 
ATOM   1788 C C   . ASN A 1 384 ? 140.153 121.447 147.396 1.00 53.84 ? 384 ASN A C   1 
ATOM   1789 O O   . ASN A 1 384 ? 141.157 122.056 147.777 1.00 53.79 ? 384 ASN A O   1 
ATOM   1790 C CB  . ASN A 1 384 ? 138.483 123.274 146.950 1.00 52.28 ? 384 ASN A CB  1 
ATOM   1791 C CG  . ASN A 1 384 ? 137.870 123.022 145.594 1.00 56.42 ? 384 ASN A CG  1 
ATOM   1792 O OD1 . ASN A 1 384 ? 136.967 122.198 145.453 1.00 54.87 ? 384 ASN A OD1 1 
ATOM   1793 N ND2 . ASN A 1 384 ? 138.347 123.743 144.587 1.00 56.80 ? 384 ASN A ND2 1 
ATOM   1794 N N   . LYS A 1 385 ? 140.206 120.316 146.687 1.00 61.23 ? 385 LYS A N   1 
ATOM   1795 C CA  . LYS A 1 385 ? 141.475 119.630 146.455 1.00 62.75 ? 385 LYS A CA  1 
ATOM   1796 C C   . LYS A 1 385 ? 142.366 120.352 145.453 1.00 61.86 ? 385 LYS A C   1 
ATOM   1797 O O   . LYS A 1 385 ? 143.559 120.038 145.367 1.00 60.22 ? 385 LYS A O   1 
ATOM   1798 C CB  . LYS A 1 385 ? 141.217 118.201 145.976 1.00 59.98 ? 385 LYS A CB  1 
ATOM   1799 N N   . THR A 1 386 ? 141.817 121.304 144.693 1.00 59.09 ? 386 THR A N   1 
ATOM   1800 C CA  . THR A 1 386 ? 142.625 122.053 143.737 1.00 60.94 ? 386 THR A CA  1 
ATOM   1801 C C   . THR A 1 386 ? 143.606 122.978 144.448 1.00 60.02 ? 386 THR A C   1 
ATOM   1802 O O   . THR A 1 386 ? 144.713 123.220 143.952 1.00 58.57 ? 386 THR A O   1 
ATOM   1803 C CB  . THR A 1 386 ? 141.719 122.848 142.799 1.00 61.87 ? 386 THR A CB  1 
ATOM   1804 O OG1 . THR A 1 386 ? 140.517 122.107 142.556 1.00 59.32 ? 386 THR A OG1 1 
ATOM   1805 C CG2 . THR A 1 386 ? 142.421 123.108 141.475 1.00 61.82 ? 386 THR A CG2 1 
ATOM   1806 N N   . TYR A 1 387 ? 143.216 123.508 145.610 1.00 51.81 ? 387 TYR A N   1 
ATOM   1807 C CA  . TYR A 1 387 ? 144.138 124.321 146.396 1.00 52.01 ? 387 TYR A CA  1 
ATOM   1808 C C   . TYR A 1 387 ? 145.228 123.473 147.034 1.00 53.49 ? 387 TYR A C   1 
ATOM   1809 O O   . TYR A 1 387 ? 146.367 123.932 147.172 1.00 54.71 ? 387 TYR A O   1 
ATOM   1810 C CB  . TYR A 1 387 ? 143.377 125.091 147.472 1.00 52.58 ? 387 TYR A CB  1 
ATOM   1811 C CG  . TYR A 1 387 ? 142.718 126.354 146.975 1.00 50.41 ? 387 TYR A CG  1 
ATOM   1812 C CD1 . TYR A 1 387 ? 143.450 127.519 146.798 1.00 47.65 ? 387 TYR A CD1 1 
ATOM   1813 C CD2 . TYR A 1 387 ? 141.360 126.383 146.694 1.00 55.73 ? 387 TYR A CD2 1 
ATOM   1814 C CE1 . TYR A 1 387 ? 142.850 128.675 146.347 1.00 47.91 ? 387 TYR A CE1 1 
ATOM   1815 C CE2 . TYR A 1 387 ? 140.751 127.534 146.244 1.00 55.84 ? 387 TYR A CE2 1 
ATOM   1816 C CZ  . TYR A 1 387 ? 141.501 128.675 146.074 1.00 49.25 ? 387 TYR A CZ  1 
ATOM   1817 O OH  . TYR A 1 387 ? 140.893 129.822 145.628 1.00 47.76 ? 387 TYR A OH  1 
ATOM   1818 N N   . ARG A 1 388 ? 144.898 122.244 147.437 1.00 57.26 ? 388 ARG A N   1 
ATOM   1819 C CA  . ARG A 1 388 ? 145.901 121.352 148.006 1.00 59.20 ? 388 ARG A CA  1 
ATOM   1820 C C   . ARG A 1 388 ? 146.861 120.833 146.944 1.00 61.70 ? 388 ARG A C   1 
ATOM   1821 O O   . ARG A 1 388 ? 148.033 120.578 147.241 1.00 58.42 ? 388 ARG A O   1 
ATOM   1822 C CB  . ARG A 1 388 ? 145.217 120.188 148.720 1.00 55.56 ? 388 ARG A CB  1 
ATOM   1823 C CG  . ARG A 1 388 ? 144.249 120.624 149.798 1.00 55.61 ? 388 ARG A CG  1 
ATOM   1824 C CD  . ARG A 1 388 ? 143.807 119.456 150.652 1.00 57.21 ? 388 ARG A CD  1 
ATOM   1825 N NE  . ARG A 1 388 ? 142.402 119.135 150.443 1.00 58.32 ? 388 ARG A NE  1 
ATOM   1826 C CZ  . ARG A 1 388 ? 141.915 117.903 150.399 1.00 61.19 ? 388 ARG A CZ  1 
ATOM   1827 N NH1 . ARG A 1 388 ? 142.698 116.846 150.538 1.00 61.21 ? 388 ARG A NH1 1 
ATOM   1828 N NH2 . ARG A 1 388 ? 140.611 117.727 150.214 1.00 58.96 ? 388 ARG A NH2 1 
ATOM   1829 N N   . SER A 1 389 ? 146.386 120.671 145.706 1.00 66.61 ? 389 SER A N   1 
ATOM   1830 C CA  . SER A 1 389 ? 147.267 120.237 144.628 1.00 65.02 ? 389 SER A CA  1 
ATOM   1831 C C   . SER A 1 389 ? 148.175 121.364 144.152 1.00 65.78 ? 389 SER A C   1 
ATOM   1832 O O   . SER A 1 389 ? 149.184 121.104 143.487 1.00 66.52 ? 389 SER A O   1 
ATOM   1833 C CB  . SER A 1 389 ? 146.442 119.693 143.462 1.00 60.53 ? 389 SER A CB  1 
ATOM   1834 N N   . ALA A 1 390 ? 147.838 122.609 144.472 1.00 60.19 ? 390 ALA A N   1 
ATOM   1835 C CA  . ALA A 1 390 ? 148.667 123.746 144.093 1.00 64.03 ? 390 ALA A CA  1 
ATOM   1836 C C   . ALA A 1 390 ? 149.818 123.929 145.077 1.00 66.06 ? 390 ALA A C   1 
ATOM   1837 O O   . ALA A 1 390 ? 149.800 124.835 145.911 1.00 65.09 ? 390 ALA A O   1 
ATOM   1838 C CB  . ALA A 1 390 ? 147.828 125.010 144.014 1.00 64.33 ? 390 ALA A CB  1 
ATOM   1839 N N   . THR B 2 4   ? 148.030 162.794 117.957 1.00 74.37 ? 4   THR B N   1 
ATOM   1840 C CA  . THR B 2 4   ? 148.350 162.075 116.730 1.00 74.95 ? 4   THR B CA  1 
ATOM   1841 C C   . THR B 2 4   ? 147.367 160.933 116.503 1.00 73.68 ? 4   THR B C   1 
ATOM   1842 O O   . THR B 2 4   ? 147.769 159.792 116.276 1.00 72.33 ? 4   THR B O   1 
ATOM   1843 C CB  . THR B 2 4   ? 149.781 161.510 116.760 1.00 76.13 ? 4   THR B CB  1 
ATOM   1844 O OG1 . THR B 2 4   ? 149.913 160.596 117.856 1.00 76.96 ? 4   THR B OG1 1 
ATOM   1845 C CG2 . THR B 2 4   ? 150.801 162.633 116.904 1.00 74.86 ? 4   THR B CG2 1 
ATOM   1846 N N   . VAL B 2 5   ? 146.076 161.253 116.576 1.00 64.94 ? 5   VAL B N   1 
ATOM   1847 C CA  . VAL B 2 5   ? 144.997 160.301 116.338 1.00 61.97 ? 5   VAL B CA  1 
ATOM   1848 C C   . VAL B 2 5   ? 144.015 160.939 115.369 1.00 56.80 ? 5   VAL B C   1 
ATOM   1849 O O   . VAL B 2 5   ? 143.659 162.113 115.521 1.00 53.72 ? 5   VAL B O   1 
ATOM   1850 C CB  . VAL B 2 5   ? 144.289 159.895 117.646 1.00 55.47 ? 5   VAL B CB  1 
ATOM   1851 C CG1 . VAL B 2 5   ? 142.972 159.175 117.356 1.00 49.03 ? 5   VAL B CG1 1 
ATOM   1852 C CG2 . VAL B 2 5   ? 145.202 159.022 118.489 1.00 57.51 ? 5   VAL B CG2 1 
ATOM   1853 N N   . SER B 2 6   ? 143.586 160.170 114.374 1.00 41.62 ? 6   SER B N   1 
ATOM   1854 C CA  . SER B 2 6   ? 142.641 160.658 113.385 1.00 41.74 ? 6   SER B CA  1 
ATOM   1855 C C   . SER B 2 6   ? 141.220 160.596 113.938 1.00 39.13 ? 6   SER B C   1 
ATOM   1856 O O   . SER B 2 6   ? 140.886 159.768 114.790 1.00 35.57 ? 6   SER B O   1 
ATOM   1857 C CB  . SER B 2 6   ? 142.768 159.852 112.097 1.00 42.47 ? 6   SER B CB  1 
ATOM   1858 O OG  . SER B 2 6   ? 142.839 158.467 112.376 1.00 40.07 ? 6   SER B OG  1 
ATOM   1859 N N   . ALA B 2 7   ? 140.369 161.499 113.447 1.00 31.54 ? 7   ALA B N   1 
ATOM   1860 C CA  . ALA B 2 7   ? 138.971 161.508 113.862 1.00 31.79 ? 7   ALA B CA  1 
ATOM   1861 C C   . ALA B 2 7   ? 138.254 160.231 113.451 1.00 28.40 ? 7   ALA B C   1 
ATOM   1862 O O   . ALA B 2 7   ? 137.372 159.751 114.177 1.00 29.20 ? 7   ALA B O   1 
ATOM   1863 C CB  . ALA B 2 7   ? 138.263 162.720 113.267 1.00 38.30 ? 7   ALA B CB  1 
ATOM   1864 N N   . GLU B 2 8   ? 138.602 159.675 112.291 1.00 32.03 ? 8   GLU B N   1 
ATOM   1865 C CA  . GLU B 2 8   ? 137.966 158.438 111.855 1.00 28.17 ? 8   GLU B CA  1 
ATOM   1866 C C   . GLU B 2 8   ? 138.321 157.283 112.780 1.00 28.91 ? 8   GLU B C   1 
ATOM   1867 O O   . GLU B 2 8   ? 137.488 156.410 113.036 1.00 35.58 ? 8   GLU B O   1 
ATOM   1868 C CB  . GLU B 2 8   ? 138.352 158.120 110.413 1.00 20.78 ? 8   GLU B CB  1 
ATOM   1869 C CG  . GLU B 2 8   ? 138.162 159.284 109.461 1.00 20.27 ? 8   GLU B CG  1 
ATOM   1870 C CD  . GLU B 2 8   ? 137.909 158.835 108.041 1.00 28.69 ? 8   GLU B CD  1 
ATOM   1871 O OE1 . GLU B 2 8   ? 138.695 159.202 107.144 1.00 26.04 ? 8   GLU B OE1 1 
ATOM   1872 O OE2 . GLU B 2 8   ? 136.919 158.110 107.819 1.00 37.81 ? 8   GLU B OE2 1 
ATOM   1873 N N   . ASP B 2 9   ? 139.548 157.264 113.303 1.00 32.89 ? 9   ASP B N   1 
ATOM   1874 C CA  . ASP B 2 9   ? 139.906 156.229 114.268 1.00 37.43 ? 9   ASP B CA  1 
ATOM   1875 C C   . ASP B 2 9   ? 139.147 156.410 115.577 1.00 37.58 ? 9   ASP B C   1 
ATOM   1876 O O   . ASP B 2 9   ? 138.739 155.427 116.205 1.00 33.30 ? 9   ASP B O   1 
ATOM   1877 C CB  . ASP B 2 9   ? 141.412 156.230 114.517 1.00 36.40 ? 9   ASP B CB  1 
ATOM   1878 C CG  . ASP B 2 9   ? 141.987 154.833 114.598 1.00 39.57 ? 9   ASP B CG  1 
ATOM   1879 O OD1 . ASP B 2 9   ? 141.307 153.940 115.145 1.00 36.02 ? 9   ASP B OD1 1 
ATOM   1880 O OD2 . ASP B 2 9   ? 143.118 154.626 114.111 1.00 41.95 ? 9   ASP B OD2 1 
ATOM   1881 N N   . LYS B 2 10  ? 138.954 157.662 116.006 1.00 36.16 ? 10  LYS B N   1 
ATOM   1882 C CA  . LYS B 2 10  ? 138.113 157.926 117.171 1.00 30.87 ? 10  LYS B CA  1 
ATOM   1883 C C   . LYS B 2 10  ? 136.713 157.363 116.966 1.00 34.12 ? 10  LYS B C   1 
ATOM   1884 O O   . LYS B 2 10  ? 136.171 156.672 117.838 1.00 34.93 ? 10  LYS B O   1 
ATOM   1885 C CB  . LYS B 2 10  ? 138.024 159.433 117.430 1.00 30.87 ? 10  LYS B CB  1 
ATOM   1886 C CG  . LYS B 2 10  ? 139.004 159.986 118.452 1.00 32.54 ? 10  LYS B CG  1 
ATOM   1887 C CD  . LYS B 2 10  ? 138.896 161.508 118.530 1.00 32.16 ? 10  LYS B CD  1 
ATOM   1888 C CE  . LYS B 2 10  ? 140.109 162.199 117.924 1.00 37.48 ? 10  LYS B CE  1 
ATOM   1889 N NZ  . LYS B 2 10  ? 139.929 163.676 117.833 1.00 37.43 ? 10  LYS B NZ  1 
ATOM   1890 N N   . ALA B 2 11  ? 136.119 157.645 115.806 1.00 27.97 ? 11  ALA B N   1 
ATOM   1891 C CA  . ALA B 2 11  ? 134.758 157.194 115.543 1.00 24.69 ? 11  ALA B CA  1 
ATOM   1892 C C   . ALA B 2 11  ? 134.689 155.677 115.424 1.00 23.87 ? 11  ALA B C   1 
ATOM   1893 O O   . ALA B 2 11  ? 133.709 155.059 115.851 1.00 27.46 ? 11  ALA B O   1 
ATOM   1894 C CB  . ALA B 2 11  ? 134.227 157.856 114.276 1.00 28.65 ? 11  ALA B CB  1 
ATOM   1895 N N   . ALA B 2 12  ? 135.718 155.058 114.842 1.00 25.54 ? 12  ALA B N   1 
ATOM   1896 C CA  . ALA B 2 12  ? 135.742 153.603 114.742 1.00 26.53 ? 12  ALA B CA  1 
ATOM   1897 C C   . ALA B 2 12  ? 135.860 152.961 116.117 1.00 27.37 ? 12  ALA B C   1 
ATOM   1898 O O   . ALA B 2 12  ? 135.223 151.937 116.390 1.00 33.53 ? 12  ALA B O   1 
ATOM   1899 C CB  . ALA B 2 12  ? 136.894 153.159 113.843 1.00 27.70 ? 12  ALA B CB  1 
ATOM   1900 N N   . ALA B 2 13  ? 136.673 153.547 116.998 1.00 35.79 ? 13  ALA B N   1 
ATOM   1901 C CA  . ALA B 2 13  ? 136.756 153.050 118.367 1.00 35.63 ? 13  ALA B CA  1 
ATOM   1902 C C   . ALA B 2 13  ? 135.421 153.197 119.082 1.00 31.25 ? 13  ALA B C   1 
ATOM   1903 O O   . ALA B 2 13  ? 135.008 152.305 119.830 1.00 24.47 ? 13  ALA B O   1 
ATOM   1904 C CB  . ALA B 2 13  ? 137.855 153.790 119.127 1.00 37.88 ? 13  ALA B CB  1 
ATOM   1905 N N   . GLU B 2 14  ? 134.734 154.323 118.871 1.00 36.76 ? 14  GLU B N   1 
ATOM   1906 C CA  . GLU B 2 14  ? 133.410 154.505 119.463 1.00 34.84 ? 14  GLU B CA  1 
ATOM   1907 C C   . GLU B 2 14  ? 132.427 153.461 118.944 1.00 31.30 ? 14  GLU B C   1 
ATOM   1908 O O   . GLU B 2 14  ? 131.618 152.919 119.708 1.00 31.15 ? 14  GLU B O   1 
ATOM   1909 C CB  . GLU B 2 14  ? 132.904 155.918 119.166 1.00 34.38 ? 14  GLU B CB  1 
ATOM   1910 C CG  . GLU B 2 14  ? 131.806 156.430 120.114 1.00 36.67 ? 14  GLU B CG  1 
ATOM   1911 C CD  . GLU B 2 14  ? 130.400 156.430 119.516 1.00 38.98 ? 14  GLU B CD  1 
ATOM   1912 O OE1 . GLU B 2 14  ? 130.244 156.414 118.277 1.00 37.87 ? 14  GLU B OE1 1 
ATOM   1913 O OE2 . GLU B 2 14  ? 129.433 156.454 120.306 1.00 35.68 ? 14  GLU B OE2 1 
ATOM   1914 N N   . ARG B 2 15  ? 132.483 153.169 117.643 1.00 33.32 ? 15  ARG B N   1 
ATOM   1915 C CA  . ARG B 2 15  ? 131.629 152.135 117.067 1.00 29.07 ? 15  ARG B CA  1 
ATOM   1916 C C   . ARG B 2 15  ? 131.925 150.776 117.685 1.00 33.62 ? 15  ARG B C   1 
ATOM   1917 O O   . ARG B 2 15  ? 131.006 150.001 117.967 1.00 41.10 ? 15  ARG B O   1 
ATOM   1918 C CB  . ARG B 2 15  ? 131.823 152.094 115.548 1.00 31.63 ? 15  ARG B CB  1 
ATOM   1919 C CG  . ARG B 2 15  ? 130.991 151.049 114.798 1.00 30.23 ? 15  ARG B CG  1 
ATOM   1920 C CD  . ARG B 2 15  ? 131.402 150.966 113.340 1.00 28.08 ? 15  ARG B CD  1 
ATOM   1921 N NE  . ARG B 2 15  ? 130.923 149.745 112.701 1.00 22.76 ? 15  ARG B NE  1 
ATOM   1922 C CZ  . ARG B 2 15  ? 129.707 149.573 112.199 1.00 27.58 ? 15  ARG B CZ  1 
ATOM   1923 N NH1 . ARG B 2 15  ? 128.782 150.519 112.265 1.00 33.90 ? 15  ARG B NH1 1 
ATOM   1924 N NH2 . ARG B 2 15  ? 129.406 148.417 111.618 1.00 22.44 ? 15  ARG B NH2 1 
ATOM   1925 N N   . SER B 2 16  ? 133.206 150.460 117.879 1.00 36.51 ? 16  SER B N   1 
ATOM   1926 C CA  . SER B 2 16  ? 133.562 149.188 118.500 1.00 34.89 ? 16  SER B CA  1 
ATOM   1927 C C   . SER B 2 16  ? 133.088 149.129 119.946 1.00 40.89 ? 16  SER B C   1 
ATOM   1928 O O   . SER B 2 16  ? 132.667 148.072 120.424 1.00 39.88 ? 16  SER B O   1 
ATOM   1929 C CB  . SER B 2 16  ? 135.069 148.967 118.426 1.00 37.32 ? 16  SER B CB  1 
ATOM   1930 O OG  . SER B 2 16  ? 135.481 148.000 119.373 1.00 33.33 ? 16  SER B OG  1 
ATOM   1931 N N   . LYS B 2 17  ? 133.159 150.254 120.663 1.00 48.69 ? 17  LYS B N   1 
ATOM   1932 C CA  . LYS B 2 17  ? 132.612 150.302 122.016 1.00 44.85 ? 17  LYS B CA  1 
ATOM   1933 C C   . LYS B 2 17  ? 131.115 150.029 122.008 1.00 41.42 ? 17  LYS B C   1 
ATOM   1934 O O   . LYS B 2 17  ? 130.607 149.293 122.861 1.00 44.99 ? 17  LYS B O   1 
ATOM   1935 C CB  . LYS B 2 17  ? 132.884 151.664 122.657 1.00 44.79 ? 17  LYS B CB  1 
ATOM   1936 C CG  . LYS B 2 17  ? 134.324 151.916 123.072 1.00 40.86 ? 17  LYS B CG  1 
ATOM   1937 C CD  . LYS B 2 17  ? 134.429 153.215 123.856 1.00 42.47 ? 17  LYS B CD  1 
ATOM   1938 C CE  . LYS B 2 17  ? 135.869 153.574 124.177 1.00 49.90 ? 17  LYS B CE  1 
ATOM   1939 N NZ  . LYS B 2 17  ? 136.640 153.986 122.971 1.00 51.49 ? 17  LYS B NZ  1 
ATOM   1940 N N   . MET B 2 18  ? 130.391 150.624 121.059 1.00 43.28 ? 18  MET B N   1 
ATOM   1941 C CA  . MET B 2 18  ? 128.951 150.393 120.974 1.00 38.83 ? 18  MET B CA  1 
ATOM   1942 C C   . MET B 2 18  ? 128.648 148.938 120.634 1.00 37.00 ? 18  MET B C   1 
ATOM   1943 O O   . MET B 2 18  ? 127.697 148.350 121.164 1.00 47.03 ? 18  MET B O   1 
ATOM   1944 C CB  . MET B 2 18  ? 128.329 151.328 119.934 1.00 45.41 ? 18  MET B CB  1 
ATOM   1945 C CG  . MET B 2 18  ? 127.675 152.580 120.528 1.00 50.16 ? 18  MET B CG  1 
ATOM   1946 S SD  . MET B 2 18  ? 126.575 153.479 119.410 1.00 69.15 ? 18  MET B SD  1 
ATOM   1947 C CE  . MET B 2 18  ? 125.367 152.233 118.965 1.00 48.85 ? 18  MET B CE  1 
ATOM   1948 N N   . ILE B 2 19  ? 129.449 148.339 119.751 1.00 38.00 ? 19  ILE B N   1 
ATOM   1949 C CA  . ILE B 2 19  ? 129.263 146.930 119.411 1.00 45.24 ? 19  ILE B CA  1 
ATOM   1950 C C   . ILE B 2 19  ? 129.526 146.057 120.631 1.00 44.52 ? 19  ILE B C   1 
ATOM   1951 O O   . ILE B 2 19  ? 128.814 145.076 120.874 1.00 47.70 ? 19  ILE B O   1 
ATOM   1952 C CB  . ILE B 2 19  ? 130.166 146.541 118.222 1.00 42.33 ? 19  ILE B CB  1 
ATOM   1953 C CG1 . ILE B 2 19  ? 129.619 147.156 116.930 1.00 40.47 ? 19  ILE B CG1 1 
ATOM   1954 C CG2 . ILE B 2 19  ? 130.260 145.013 118.093 1.00 37.83 ? 19  ILE B CG2 1 
ATOM   1955 C CD1 . ILE B 2 19  ? 130.563 147.084 115.749 1.00 39.18 ? 19  ILE B CD1 1 
ATOM   1956 N N   . ASP B 2 20  ? 130.560 146.388 121.407 1.00 43.97 ? 20  ASP B N   1 
ATOM   1957 C CA  . ASP B 2 20  ? 130.835 145.647 122.633 1.00 45.60 ? 20  ASP B CA  1 
ATOM   1958 C C   . ASP B 2 20  ? 129.688 145.787 123.625 1.00 49.89 ? 20  ASP B C   1 
ATOM   1959 O O   . ASP B 2 20  ? 129.334 144.825 124.310 1.00 46.10 ? 20  ASP B O   1 
ATOM   1960 C CB  . ASP B 2 20  ? 132.141 146.137 123.268 1.00 48.93 ? 20  ASP B CB  1 
ATOM   1961 C CG  . ASP B 2 20  ? 133.363 145.341 122.823 1.00 48.02 ? 20  ASP B CG  1 
ATOM   1962 O OD1 . ASP B 2 20  ? 133.238 144.147 122.482 1.00 48.29 ? 20  ASP B OD1 1 
ATOM   1963 O OD2 . ASP B 2 20  ? 134.467 145.922 122.819 1.00 46.30 ? 20  ASP B OD2 1 
ATOM   1964 N N   . LYS B 2 21  ? 129.109 146.984 123.726 1.00 58.22 ? 21  LYS B N   1 
ATOM   1965 C CA  . LYS B 2 21  ? 127.958 147.190 124.602 1.00 54.24 ? 21  LYS B CA  1 
ATOM   1966 C C   . LYS B 2 21  ? 126.784 146.320 124.173 1.00 50.44 ? 21  LYS B C   1 
ATOM   1967 O O   . LYS B 2 21  ? 126.123 145.687 125.007 1.00 55.93 ? 21  LYS B O   1 
ATOM   1968 C CB  . LYS B 2 21  ? 127.577 148.675 124.603 1.00 56.96 ? 21  LYS B CB  1 
ATOM   1969 C CG  . LYS B 2 21  ? 126.302 149.043 125.362 1.00 56.83 ? 21  LYS B CG  1 
ATOM   1970 C CD  . LYS B 2 21  ? 125.093 149.177 124.434 1.00 58.22 ? 21  LYS B CD  1 
ATOM   1971 C CE  . LYS B 2 21  ? 123.837 149.572 125.195 1.00 59.89 ? 21  LYS B CE  1 
ATOM   1972 N NZ  . LYS B 2 21  ? 122.877 150.313 124.328 1.00 59.80 ? 21  LYS B NZ  1 
ATOM   1973 N N   . ASN B 2 22  ? 126.508 146.277 122.868 1.00 49.56 ? 22  ASN B N   1 
ATOM   1974 C CA  . ASN B 2 22  ? 125.401 145.461 122.381 1.00 53.21 ? 22  ASN B CA  1 
ATOM   1975 C C   . ASN B 2 22  ? 125.664 143.979 122.619 1.00 51.99 ? 22  ASN B C   1 
ATOM   1976 O O   . ASN B 2 22  ? 124.755 143.232 122.998 1.00 55.22 ? 22  ASN B O   1 
ATOM   1977 C CB  . ASN B 2 22  ? 125.161 145.730 120.897 1.00 55.48 ? 22  ASN B CB  1 
ATOM   1978 C CG  . ASN B 2 22  ? 123.891 145.079 120.387 1.00 56.10 ? 22  ASN B CG  1 
ATOM   1979 O OD1 . ASN B 2 22  ? 122.871 145.067 121.076 1.00 55.70 ? 22  ASN B OD1 1 
ATOM   1980 N ND2 . ASN B 2 22  ? 123.941 144.541 119.174 1.00 57.83 ? 22  ASN B ND2 1 
ATOM   1981 N N   . LEU B 2 23  ? 126.906 143.537 122.404 1.00 52.51 ? 23  LEU B N   1 
ATOM   1982 C CA  . LEU B 2 23  ? 127.257 142.144 122.668 1.00 48.55 ? 23  LEU B CA  1 
ATOM   1983 C C   . LEU B 2 23  ? 127.125 141.816 124.148 1.00 54.77 ? 23  LEU B C   1 
ATOM   1984 O O   . LEU B 2 23  ? 126.648 140.736 124.510 1.00 52.51 ? 23  LEU B O   1 
ATOM   1985 C CB  . LEU B 2 23  ? 128.682 141.856 122.188 1.00 47.84 ? 23  LEU B CB  1 
ATOM   1986 C CG  . LEU B 2 23  ? 128.937 141.749 120.682 1.00 48.28 ? 23  LEU B CG  1 
ATOM   1987 C CD1 . LEU B 2 23  ? 130.421 141.552 120.420 1.00 49.16 ? 23  LEU B CD1 1 
ATOM   1988 C CD2 . LEU B 2 23  ? 128.139 140.616 120.059 1.00 45.80 ? 23  LEU B CD2 1 
ATOM   1989 N N   . ARG B 2 24  ? 127.550 142.736 125.018 1.00 59.78 ? 24  ARG B N   1 
ATOM   1990 C CA  . ARG B 2 24  ? 127.391 142.548 126.456 1.00 55.12 ? 24  ARG B CA  1 
ATOM   1991 C C   . ARG B 2 24  ? 125.924 142.387 126.822 1.00 53.96 ? 24  ARG B C   1 
ATOM   1992 O O   . ARG B 2 24  ? 125.556 141.472 127.564 1.00 52.67 ? 24  ARG B O   1 
ATOM   1993 C CB  . ARG B 2 24  ? 127.994 143.739 127.205 1.00 59.37 ? 24  ARG B CB  1 
ATOM   1994 C CG  . ARG B 2 24  ? 129.511 143.722 127.326 1.00 60.56 ? 24  ARG B CG  1 
ATOM   1995 C CD  . ARG B 2 24  ? 130.067 145.080 127.764 1.00 58.26 ? 24  ARG B CD  1 
ATOM   1996 N NE  . ARG B 2 24  ? 129.186 145.764 128.711 1.00 61.94 ? 24  ARG B NE  1 
ATOM   1997 C CZ  . ARG B 2 24  ? 128.828 147.045 128.672 1.00 64.85 ? 24  ARG B CZ  1 
ATOM   1998 N NH1 . ARG B 2 24  ? 129.311 147.887 127.770 1.00 60.76 ? 24  ARG B NH1 1 
ATOM   1999 N NH2 . ARG B 2 24  ? 127.967 147.501 129.578 1.00 63.87 ? 24  ARG B NH2 1 
ATOM   2000 N N   . GLU B 2 25  ? 125.070 143.274 126.304 1.00 60.09 ? 25  GLU B N   1 
ATOM   2001 C CA  . GLU B 2 25  ? 123.647 143.215 126.627 1.00 60.68 ? 25  GLU B CA  1 
ATOM   2002 C C   . GLU B 2 25  ? 123.026 141.913 126.131 1.00 57.52 ? 25  GLU B C   1 
ATOM   2003 O O   . GLU B 2 25  ? 122.278 141.247 126.859 1.00 62.17 ? 25  GLU B O   1 
ATOM   2004 C CB  . GLU B 2 25  ? 122.932 144.426 126.023 1.00 61.44 ? 25  GLU B CB  1 
ATOM   2005 C CG  . GLU B 2 25  ? 121.413 144.381 126.108 1.00 63.48 ? 25  GLU B CG  1 
ATOM   2006 C CD  . GLU B 2 25  ? 120.779 145.728 125.824 1.00 63.32 ? 25  GLU B CD  1 
ATOM   2007 O OE1 . GLU B 2 25  ? 121.369 146.512 125.052 1.00 58.90 ? 25  GLU B OE1 1 
ATOM   2008 O OE2 . GLU B 2 25  ? 119.691 146.004 126.373 1.00 61.07 ? 25  GLU B OE2 1 
ATOM   2009 N N   . ASP B 2 26  ? 123.338 141.528 124.892 1.00 53.50 ? 26  ASP B N   1 
ATOM   2010 C CA  . ASP B 2 26  ? 122.761 140.313 124.327 1.00 53.34 ? 26  ASP B CA  1 
ATOM   2011 C C   . ASP B 2 26  ? 123.235 139.073 125.078 1.00 57.60 ? 26  ASP B C   1 
ATOM   2012 O O   . ASP B 2 26  ? 122.442 138.166 125.351 1.00 60.91 ? 26  ASP B O   1 
ATOM   2013 C CB  . ASP B 2 26  ? 123.110 140.213 122.842 1.00 55.82 ? 26  ASP B CB  1 
ATOM   2014 C CG  . ASP B 2 26  ? 122.310 139.145 122.123 1.00 57.54 ? 26  ASP B CG  1 
ATOM   2015 O OD1 . ASP B 2 26  ? 121.487 138.466 122.772 1.00 56.48 ? 26  ASP B OD1 1 
ATOM   2016 O OD2 . ASP B 2 26  ? 122.502 138.989 120.899 1.00 55.84 ? 26  ASP B OD2 1 
ATOM   2017 N N   . GLY B 2 27  ? 124.523 139.012 125.418 1.00 58.33 ? 27  GLY B N   1 
ATOM   2018 C CA  . GLY B 2 27  ? 125.023 137.872 126.167 1.00 57.96 ? 27  GLY B CA  1 
ATOM   2019 C C   . GLY B 2 27  ? 124.464 137.809 127.574 1.00 60.66 ? 27  GLY B C   1 
ATOM   2020 O O   . GLY B 2 27  ? 124.194 136.724 128.096 1.00 62.58 ? 27  GLY B O   1 
ATOM   2021 N N   . GLU B 2 28  ? 124.295 138.969 128.212 1.00 66.60 ? 28  GLU B N   1 
ATOM   2022 C CA  . GLU B 2 28  ? 123.673 139.014 129.528 1.00 64.41 ? 28  GLU B CA  1 
ATOM   2023 C C   . GLU B 2 28  ? 122.250 138.479 129.466 1.00 62.91 ? 28  GLU B C   1 
ATOM   2024 O O   . GLU B 2 28  ? 121.828 137.713 130.339 1.00 62.90 ? 28  GLU B O   1 
ATOM   2025 C CB  . GLU B 2 28  ? 123.684 140.452 130.049 1.00 65.76 ? 28  GLU B CB  1 
ATOM   2026 C CG  . GLU B 2 28  ? 123.449 140.601 131.542 1.00 68.49 ? 28  GLU B CG  1 
ATOM   2027 C CD  . GLU B 2 28  ? 124.637 140.155 132.375 1.00 70.85 ? 28  GLU B CD  1 
ATOM   2028 O OE1 . GLU B 2 28  ? 125.784 140.244 131.888 1.00 67.19 ? 28  GLU B OE1 1 
ATOM   2029 O OE2 . GLU B 2 28  ? 124.422 139.714 133.524 1.00 73.25 ? 28  GLU B OE2 1 
ATOM   2030 N N   . LYS B 2 29  ? 121.500 138.869 128.433 1.00 63.56 ? 29  LYS B N   1 
ATOM   2031 C CA  . LYS B 2 29  ? 120.137 138.372 128.283 1.00 64.31 ? 29  LYS B CA  1 
ATOM   2032 C C   . LYS B 2 29  ? 120.115 136.878 127.978 1.00 60.59 ? 29  LYS B C   1 
ATOM   2033 O O   . LYS B 2 29  ? 119.238 136.158 128.468 1.00 62.13 ? 29  LYS B O   1 
ATOM   2034 C CB  . LYS B 2 29  ? 119.414 139.189 127.201 1.00 64.10 ? 29  LYS B CB  1 
ATOM   2035 C CG  . LYS B 2 29  ? 118.117 138.602 126.621 1.00 61.16 ? 29  LYS B CG  1 
ATOM   2036 C CD  . LYS B 2 29  ? 118.324 137.713 125.390 1.00 62.46 ? 29  LYS B CD  1 
ATOM   2037 C CE  . LYS B 2 29  ? 117.054 136.954 125.047 1.00 66.20 ? 29  LYS B CE  1 
ATOM   2038 N NZ  . LYS B 2 29  ? 117.245 136.041 123.889 1.00 68.05 ? 29  LYS B NZ  1 
ATOM   2039 N N   . ALA B 2 30  ? 121.062 136.393 127.173 1.00 59.13 ? 30  ALA B N   1 
ATOM   2040 C CA  . ALA B 2 30  ? 121.026 135.011 126.706 1.00 61.93 ? 30  ALA B CA  1 
ATOM   2041 C C   . ALA B 2 30  ? 121.377 133.991 127.782 1.00 63.36 ? 30  ALA B C   1 
ATOM   2042 O O   . ALA B 2 30  ? 121.077 132.806 127.606 1.00 60.43 ? 30  ALA B O   1 
ATOM   2043 C CB  . ALA B 2 30  ? 121.979 134.834 125.523 1.00 66.28 ? 30  ALA B CB  1 
ATOM   2044 N N   . ARG B 2 31  ? 122.011 134.406 128.880 1.00 67.50 ? 31  ARG B N   1 
ATOM   2045 C CA  . ARG B 2 31  ? 122.410 133.449 129.907 1.00 67.01 ? 31  ARG B CA  1 
ATOM   2046 C C   . ARG B 2 31  ? 121.242 133.012 130.785 1.00 64.39 ? 31  ARG B C   1 
ATOM   2047 O O   . ARG B 2 31  ? 121.343 131.971 131.442 1.00 61.57 ? 31  ARG B O   1 
ATOM   2048 C CB  . ARG B 2 31  ? 123.513 134.058 130.781 1.00 66.21 ? 31  ARG B CB  1 
ATOM   2049 C CG  . ARG B 2 31  ? 124.103 133.104 131.848 1.00 64.70 ? 31  ARG B CG  1 
ATOM   2050 C CD  . ARG B 2 31  ? 125.203 133.694 132.758 1.00 67.75 ? 31  ARG B CD  1 
ATOM   2051 N NE  . ARG B 2 31  ? 125.256 135.150 132.876 1.00 70.23 ? 31  ARG B NE  1 
ATOM   2052 C CZ  . ARG B 2 31  ? 124.284 135.918 133.355 1.00 67.72 ? 31  ARG B CZ  1 
ATOM   2053 N NH1 . ARG B 2 31  ? 123.142 135.407 133.793 1.00 65.82 ? 31  ARG B NH1 1 
ATOM   2054 N NH2 . ARG B 2 31  ? 124.464 137.233 133.405 1.00 66.63 ? 31  ARG B NH2 1 
ATOM   2055 N N   . ARG B 2 32  ? 120.174 133.804 130.857 1.00 60.44 ? 32  ARG B N   1 
ATOM   2056 C CA  . ARG B 2 32  ? 119.080 133.488 131.817 1.00 59.29 ? 32  ARG B CA  1 
ATOM   2057 C C   . ARG B 2 32  ? 118.513 132.074 131.609 1.00 61.32 ? 32  ARG B C   1 
ATOM   2058 O O   . ARG B 2 32  ? 118.178 131.431 132.625 1.00 65.05 ? 32  ARG B O   1 
ATOM   2059 C CB  . ARG B 2 32  ? 117.986 134.551 131.676 1.00 62.64 ? 32  ARG B CB  1 
ATOM   2060 C CG  . ARG B 2 32  ? 118.557 135.961 131.713 1.00 62.11 ? 32  ARG B CG  1 
ATOM   2061 C CD  . ARG B 2 32  ? 117.485 137.030 131.570 1.00 60.57 ? 32  ARG B CD  1 
ATOM   2062 N NE  . ARG B 2 32  ? 116.579 137.091 132.723 1.00 66.54 ? 32  ARG B NE  1 
ATOM   2063 C CZ  . ARG B 2 32  ? 116.933 137.407 133.963 1.00 65.54 ? 32  ARG B CZ  1 
ATOM   2064 N NH1 . ARG B 2 32  ? 118.133 137.902 134.209 1.00 66.54 ? 32  ARG B NH1 1 
ATOM   2065 N NH2 . ARG B 2 32  ? 116.077 137.238 134.955 1.00 60.55 ? 32  ARG B NH2 1 
ATOM   2066 N N   . THR B 2 33  ? 118.448 131.580 130.372 1.00 54.46 ? 33  THR B N   1 
ATOM   2067 C CA  . THR B 2 33  ? 117.786 130.313 130.101 1.00 54.09 ? 33  THR B CA  1 
ATOM   2068 C C   . THR B 2 33  ? 118.757 129.144 130.234 1.00 51.79 ? 33  THR B C   1 
ATOM   2069 O O   . THR B 2 33  ? 119.965 129.277 130.030 1.00 53.18 ? 33  THR B O   1 
ATOM   2070 C CB  . THR B 2 33  ? 117.167 130.314 128.705 1.00 50.36 ? 33  THR B CB  1 
ATOM   2071 O OG1 . THR B 2 33  ? 116.265 129.209 128.594 1.00 52.99 ? 33  THR B OG1 1 
ATOM   2072 C CG2 . THR B 2 33  ? 118.239 130.204 127.626 1.00 50.88 ? 33  THR B CG2 1 
ATOM   2073 N N   . LEU B 2 34  ? 118.199 127.986 130.575 1.00 46.12 ? 34  LEU B N   1 
ATOM   2074 C CA  . LEU B 2 34  ? 118.943 126.747 130.737 1.00 43.28 ? 34  LEU B CA  1 
ATOM   2075 C C   . LEU B 2 34  ? 118.799 125.905 129.476 1.00 46.57 ? 34  LEU B C   1 
ATOM   2076 O O   . LEU B 2 34  ? 117.855 126.069 128.699 1.00 48.79 ? 34  LEU B O   1 
ATOM   2077 C CB  . LEU B 2 34  ? 118.435 125.963 131.955 1.00 39.84 ? 34  LEU B CB  1 
ATOM   2078 C CG  . LEU B 2 34  ? 118.804 126.406 133.383 1.00 42.69 ? 34  LEU B CG  1 
ATOM   2079 C CD1 . LEU B 2 34  ? 118.794 125.209 134.315 1.00 45.69 ? 34  LEU B CD1 1 
ATOM   2080 C CD2 . LEU B 2 34  ? 120.142 127.134 133.498 1.00 45.12 ? 34  LEU B CD2 1 
ATOM   2081 N N   . ARG B 2 35  ? 119.746 124.987 129.290 1.00 43.68 ? 35  ARG B N   1 
ATOM   2082 C CA  . ARG B 2 35  ? 119.890 124.235 128.052 1.00 41.07 ? 35  ARG B CA  1 
ATOM   2083 C C   . ARG B 2 35  ? 119.917 122.745 128.350 1.00 45.28 ? 35  ARG B C   1 
ATOM   2084 O O   . ARG B 2 35  ? 120.547 122.307 129.317 1.00 45.98 ? 35  ARG B O   1 
ATOM   2085 C CB  . ARG B 2 35  ? 121.169 124.646 127.323 1.00 42.23 ? 35  ARG B CB  1 
ATOM   2086 C CG  . ARG B 2 35  ? 121.269 124.139 125.894 1.00 49.34 ? 35  ARG B CG  1 
ATOM   2087 C CD  . ARG B 2 35  ? 122.280 124.927 125.057 1.00 49.65 ? 35  ARG B CD  1 
ATOM   2088 N NE  . ARG B 2 35  ? 121.898 126.324 124.856 1.00 49.47 ? 35  ARG B NE  1 
ATOM   2089 C CZ  . ARG B 2 35  ? 122.342 127.364 125.556 1.00 50.80 ? 35  ARG B CZ  1 
ATOM   2090 N NH1 . ARG B 2 35  ? 123.197 127.224 126.559 1.00 46.71 ? 35  ARG B NH1 1 
ATOM   2091 N NH2 . ARG B 2 35  ? 121.907 128.583 125.247 1.00 48.61 ? 35  ARG B NH2 1 
ATOM   2092 N N   . LEU B 2 36  ? 119.231 121.972 127.508 1.00 41.19 ? 36  LEU B N   1 
ATOM   2093 C CA  . LEU B 2 36  ? 119.112 120.530 127.667 1.00 36.77 ? 36  LEU B CA  1 
ATOM   2094 C C   . LEU B 2 36  ? 119.306 119.860 126.316 1.00 38.04 ? 36  LEU B C   1 
ATOM   2095 O O   . LEU B 2 36  ? 118.963 120.426 125.275 1.00 45.69 ? 36  LEU B O   1 
ATOM   2096 C CB  . LEU B 2 36  ? 117.747 120.143 128.249 1.00 37.19 ? 36  LEU B CB  1 
ATOM   2097 C CG  . LEU B 2 36  ? 117.449 120.667 129.653 1.00 33.92 ? 36  LEU B CG  1 
ATOM   2098 C CD1 . LEU B 2 36  ? 115.970 120.560 129.963 1.00 35.25 ? 36  LEU B CD1 1 
ATOM   2099 C CD2 . LEU B 2 36  ? 118.263 119.909 130.684 1.00 38.81 ? 36  LEU B CD2 1 
ATOM   2100 N N   . LEU B 2 37  ? 119.856 118.649 126.345 1.00 32.12 ? 37  LEU B N   1 
ATOM   2101 C CA  . LEU B 2 37  ? 120.093 117.846 125.151 1.00 32.38 ? 37  LEU B CA  1 
ATOM   2102 C C   . LEU B 2 37  ? 119.347 116.529 125.303 1.00 32.29 ? 37  LEU B C   1 
ATOM   2103 O O   . LEU B 2 37  ? 119.735 115.684 126.116 1.00 44.32 ? 37  LEU B O   1 
ATOM   2104 C CB  . LEU B 2 37  ? 121.590 117.609 124.944 1.00 35.05 ? 37  LEU B CB  1 
ATOM   2105 C CG  . LEU B 2 37  ? 122.044 116.427 124.080 1.00 35.90 ? 37  LEU B CG  1 
ATOM   2106 C CD1 . LEU B 2 37  ? 121.454 116.531 122.687 1.00 37.91 ? 37  LEU B CD1 1 
ATOM   2107 C CD2 . LEU B 2 37  ? 123.557 116.375 123.998 1.00 37.69 ? 37  LEU B CD2 1 
ATOM   2108 N N   . LEU B 2 38  ? 118.293 116.350 124.513 1.00 30.35 ? 38  LEU B N   1 
ATOM   2109 C CA  . LEU B 2 38  ? 117.463 115.154 124.556 1.00 30.90 ? 38  LEU B CA  1 
ATOM   2110 C C   . LEU B 2 38  ? 117.908 114.224 123.437 1.00 36.17 ? 38  LEU B C   1 
ATOM   2111 O O   . LEU B 2 38  ? 118.011 114.646 122.281 1.00 49.46 ? 38  LEU B O   1 
ATOM   2112 C CB  . LEU B 2 38  ? 115.983 115.515 124.413 1.00 36.25 ? 38  LEU B CB  1 
ATOM   2113 C CG  . LEU B 2 38  ? 114.984 114.419 124.023 1.00 32.22 ? 38  LEU B CG  1 
ATOM   2114 C CD1 . LEU B 2 38  ? 115.000 113.318 125.058 1.00 37.63 ? 38  LEU B CD1 1 
ATOM   2115 C CD2 . LEU B 2 38  ? 113.586 114.986 123.888 1.00 34.27 ? 38  LEU B CD2 1 
ATOM   2116 N N   . LEU B 2 39  ? 118.170 112.964 123.777 1.00 33.77 ? 39  LEU B N   1 
ATOM   2117 C CA  . LEU B 2 39  ? 118.586 111.976 122.792 1.00 41.98 ? 39  LEU B CA  1 
ATOM   2118 C C   . LEU B 2 39  ? 118.193 110.583 123.253 1.00 38.83 ? 39  LEU B C   1 
ATOM   2119 O O   . LEU B 2 39  ? 118.222 110.287 124.450 1.00 33.68 ? 39  LEU B O   1 
ATOM   2120 C CB  . LEU B 2 39  ? 120.098 112.055 122.535 1.00 40.50 ? 39  LEU B CB  1 
ATOM   2121 C CG  . LEU B 2 39  ? 121.059 112.154 123.725 1.00 35.39 ? 39  LEU B CG  1 
ATOM   2122 C CD1 . LEU B 2 39  ? 121.133 110.860 124.522 1.00 36.02 ? 39  LEU B CD1 1 
ATOM   2123 C CD2 . LEU B 2 39  ? 122.443 112.558 123.238 1.00 39.99 ? 39  LEU B CD2 1 
ATOM   2124 N N   . GLY B 2 40  ? 117.815 109.744 122.301 1.00 47.79 ? 40  GLY B N   1 
ATOM   2125 C CA  . GLY B 2 40  ? 117.492 108.359 122.585 1.00 43.02 ? 40  GLY B CA  1 
ATOM   2126 C C   . GLY B 2 40  ? 117.774 107.510 121.367 1.00 45.18 ? 40  GLY B C   1 
ATOM   2127 O O   . GLY B 2 40  ? 117.891 108.015 120.248 1.00 40.85 ? 40  GLY B O   1 
ATOM   2128 N N   . ALA B 2 41  ? 117.896 106.203 121.596 1.00 64.52 ? 41  ALA B N   1 
ATOM   2129 C CA  . ALA B 2 41  ? 118.255 105.289 120.519 1.00 69.92 ? 41  ALA B CA  1 
ATOM   2130 C C   . ALA B 2 41  ? 117.196 105.274 119.423 1.00 67.91 ? 41  ALA B C   1 
ATOM   2131 O O   . ALA B 2 41  ? 117.439 105.754 118.311 1.00 68.22 ? 41  ALA B O   1 
ATOM   2132 C CB  . ALA B 2 41  ? 118.462 103.877 121.070 1.00 63.90 ? 41  ALA B CB  1 
ATOM   2133 N N   . ASP B 2 42  ? 116.014 104.752 119.738 1.00 61.07 ? 42  ASP B N   1 
ATOM   2134 C CA  . ASP B 2 42  ? 114.886 104.674 118.815 1.00 58.78 ? 42  ASP B CA  1 
ATOM   2135 C C   . ASP B 2 42  ? 113.731 104.051 119.586 1.00 63.49 ? 42  ASP B C   1 
ATOM   2136 O O   . ASP B 2 42  ? 113.915 103.524 120.688 1.00 62.69 ? 42  ASP B O   1 
ATOM   2137 C CB  . ASP B 2 42  ? 115.185 103.850 117.555 1.00 62.59 ? 42  ASP B CB  1 
ATOM   2138 C CG  . ASP B 2 42  ? 114.292 104.225 116.387 1.00 63.60 ? 42  ASP B CG  1 
ATOM   2139 O OD1 . ASP B 2 42  ? 113.241 104.859 116.617 1.00 61.16 ? 42  ASP B OD1 1 
ATOM   2140 O OD2 . ASP B 2 42  ? 114.638 103.878 115.239 1.00 64.40 ? 42  ASP B OD2 1 
ATOM   2141 N N   . ASN B 2 43  ? 112.534 104.125 118.991 1.00 62.33 ? 43  ASN B N   1 
ATOM   2142 C CA  . ASN B 2 43  ? 111.294 103.533 119.501 1.00 62.36 ? 43  ASN B CA  1 
ATOM   2143 C C   . ASN B 2 43  ? 111.079 103.783 120.991 1.00 59.26 ? 43  ASN B C   1 
ATOM   2144 O O   . ASN B 2 43  ? 110.507 102.940 121.690 1.00 61.46 ? 43  ASN B O   1 
ATOM   2145 C CB  . ASN B 2 43  ? 111.253 102.023 119.208 1.00 61.56 ? 43  ASN B CB  1 
ATOM   2146 C CG  . ASN B 2 43  ? 112.261 101.225 120.021 1.00 59.53 ? 43  ASN B CG  1 
ATOM   2147 O OD1 . ASN B 2 43  ? 113.411 101.059 119.614 1.00 56.90 ? 43  ASN B OD1 1 
ATOM   2148 N ND2 . ASN B 2 43  ? 111.832 100.726 121.174 1.00 57.56 ? 43  ASN B ND2 1 
ATOM   2149 N N   . SER B 2 44  ? 111.515 104.949 121.474 1.00 42.24 ? 44  SER B N   1 
ATOM   2150 C CA  . SER B 2 44  ? 111.433 105.310 122.880 1.00 37.30 ? 44  SER B CA  1 
ATOM   2151 C C   . SER B 2 44  ? 110.419 106.405 123.170 1.00 40.78 ? 44  SER B C   1 
ATOM   2152 O O   . SER B 2 44  ? 110.177 106.699 124.345 1.00 42.47 ? 44  SER B O   1 
ATOM   2153 C CB  . SER B 2 44  ? 112.809 105.764 123.389 1.00 39.30 ? 44  SER B CB  1 
ATOM   2154 O OG  . SER B 2 44  ? 113.438 106.617 122.450 1.00 39.32 ? 44  SER B OG  1 
ATOM   2155 N N   . GLY B 2 45  ? 109.821 107.010 122.149 1.00 45.66 ? 45  GLY B N   1 
ATOM   2156 C CA  . GLY B 2 45  ? 108.878 108.091 122.380 1.00 43.76 ? 45  GLY B CA  1 
ATOM   2157 C C   . GLY B 2 45  ? 109.513 109.305 123.019 1.00 40.34 ? 45  GLY B C   1 
ATOM   2158 O O   . GLY B 2 45  ? 108.883 109.965 123.855 1.00 40.97 ? 45  GLY B O   1 
ATOM   2159 N N   . LYS B 2 46  ? 110.755 109.619 122.642 1.00 40.11 ? 46  LYS B N   1 
ATOM   2160 C CA  . LYS B 2 46  ? 111.429 110.781 123.207 1.00 43.25 ? 46  LYS B CA  1 
ATOM   2161 C C   . LYS B 2 46  ? 110.740 112.086 122.835 1.00 44.61 ? 46  LYS B C   1 
ATOM   2162 O O   . LYS B 2 46  ? 110.904 113.082 123.546 1.00 47.83 ? 46  LYS B O   1 
ATOM   2163 C CB  . LYS B 2 46  ? 112.893 110.826 122.758 1.00 39.22 ? 46  LYS B CB  1 
ATOM   2164 C CG  . LYS B 2 46  ? 113.116 110.803 121.255 1.00 35.63 ? 46  LYS B CG  1 
ATOM   2165 C CD  . LYS B 2 46  ? 114.587 110.988 120.927 1.00 36.27 ? 46  LYS B CD  1 
ATOM   2166 C CE  . LYS B 2 46  ? 114.816 111.093 119.432 1.00 40.16 ? 46  LYS B CE  1 
ATOM   2167 N NZ  . LYS B 2 46  ? 116.224 111.450 119.111 1.00 41.35 ? 46  LYS B NZ  1 
ATOM   2168 N N   . SER B 2 47  ? 109.979 112.108 121.740 1.00 46.27 ? 47  SER B N   1 
ATOM   2169 C CA  . SER B 2 47  ? 109.264 113.322 121.366 1.00 51.18 ? 47  SER B CA  1 
ATOM   2170 C C   . SER B 2 47  ? 108.173 113.667 122.370 1.00 53.96 ? 47  SER B C   1 
ATOM   2171 O O   . SER B 2 47  ? 107.955 114.848 122.663 1.00 50.20 ? 47  SER B O   1 
ATOM   2172 C CB  . SER B 2 47  ? 108.664 113.161 119.970 1.00 52.89 ? 47  SER B CB  1 
ATOM   2173 O OG  . SER B 2 47  ? 108.078 111.881 119.815 1.00 52.76 ? 47  SER B OG  1 
ATOM   2174 N N   . THR B 2 48  ? 107.488 112.659 122.914 1.00 48.90 ? 48  THR B N   1 
ATOM   2175 C CA  . THR B 2 48  ? 106.315 112.861 123.756 1.00 48.57 ? 48  THR B CA  1 
ATOM   2176 C C   . THR B 2 48  ? 106.672 112.995 125.236 1.00 50.55 ? 48  THR B C   1 
ATOM   2177 O O   . THR B 2 48  ? 105.817 112.780 126.101 1.00 51.38 ? 48  THR B O   1 
ATOM   2178 C CB  . THR B 2 48  ? 105.330 111.709 123.552 1.00 48.39 ? 48  THR B CB  1 
ATOM   2179 O OG1 . THR B 2 48  ? 105.374 111.280 122.186 1.00 48.53 ? 48  THR B OG1 1 
ATOM   2180 C CG2 . THR B 2 48  ? 103.899 112.136 123.882 1.00 52.00 ? 48  THR B CG2 1 
ATOM   2181 N N   . ILE B 2 49  ? 107.920 113.342 125.549 1.00 47.84 ? 49  ILE B N   1 
ATOM   2182 C CA  . ILE B 2 49  ? 108.314 113.523 126.945 1.00 47.11 ? 49  ILE B CA  1 
ATOM   2183 C C   . ILE B 2 49  ? 107.562 114.697 127.561 1.00 54.03 ? 49  ILE B C   1 
ATOM   2184 O O   . ILE B 2 49  ? 107.010 114.592 128.662 1.00 51.01 ? 49  ILE B O   1 
ATOM   2185 C CB  . ILE B 2 49  ? 109.840 113.712 127.053 1.00 42.74 ? 49  ILE B CB  1 
ATOM   2186 C CG1 . ILE B 2 49  ? 110.593 112.437 126.645 1.00 40.02 ? 49  ILE B CG1 1 
ATOM   2187 C CG2 . ILE B 2 49  ? 110.234 114.119 128.466 1.00 41.87 ? 49  ILE B CG2 1 
ATOM   2188 C CD1 . ILE B 2 49  ? 110.481 111.267 127.617 1.00 41.15 ? 49  ILE B CD1 1 
ATOM   2189 N N   . VAL B 2 50  ? 107.532 115.827 126.858 1.00 63.02 ? 50  VAL B N   1 
ATOM   2190 C CA  . VAL B 2 50  ? 106.780 117.012 127.260 1.00 56.11 ? 50  VAL B CA  1 
ATOM   2191 C C   . VAL B 2 50  ? 105.920 117.411 126.071 1.00 58.30 ? 50  VAL B C   1 
ATOM   2192 O O   . VAL B 2 50  ? 106.441 117.638 124.971 1.00 60.22 ? 50  VAL B O   1 
ATOM   2193 C CB  . VAL B 2 50  ? 107.696 118.164 127.691 1.00 52.56 ? 50  VAL B CB  1 
ATOM   2194 C CG1 . VAL B 2 50  ? 106.899 119.225 128.435 1.00 56.11 ? 50  VAL B CG1 1 
ATOM   2195 C CG2 . VAL B 2 50  ? 108.840 117.643 128.548 1.00 49.81 ? 50  VAL B CG2 1 
ATOM   2196 N N   . LYS B 2 51  ? 104.609 117.502 126.291 1.00 68.83 ? 51  LYS B N   1 
ATOM   2197 C CA  . LYS B 2 51  ? 103.640 117.773 125.237 1.00 72.14 ? 51  LYS B CA  1 
ATOM   2198 C C   . LYS B 2 51  ? 102.700 118.925 125.548 1.00 71.29 ? 51  LYS B C   1 
ATOM   2199 O O   . LYS B 2 51  ? 102.205 119.563 124.616 1.00 69.72 ? 51  LYS B O   1 
ATOM   2200 C CB  . LYS B 2 51  ? 102.802 116.515 124.956 1.00 70.88 ? 51  LYS B CB  1 
ATOM   2201 C CG  . LYS B 2 51  ? 102.326 115.796 126.211 1.00 69.31 ? 51  LYS B CG  1 
ATOM   2202 C CD  . LYS B 2 51  ? 101.195 114.821 125.913 1.00 68.90 ? 51  LYS B CD  1 
ATOM   2203 C CE  . LYS B 2 51  ? 99.842  115.515 125.830 1.00 70.09 ? 51  LYS B CE  1 
ATOM   2204 N NZ  . LYS B 2 51  ? 99.380  116.023 127.152 1.00 70.20 ? 51  LYS B NZ  1 
ATOM   2205 N N   . GLN B 2 52  ? 102.433 119.205 126.826 1.00 76.77 ? 52  GLN B N   1 
ATOM   2206 C CA  . GLN B 2 52  ? 101.555 120.318 127.169 1.00 76.91 ? 52  GLN B CA  1 
ATOM   2207 C C   . GLN B 2 52  ? 102.151 121.647 126.724 1.00 76.38 ? 52  GLN B C   1 
ATOM   2208 O O   . GLN B 2 52  ? 101.436 122.514 126.205 1.00 74.09 ? 52  GLN B O   1 
ATOM   2209 C CB  . GLN B 2 52  ? 101.289 120.328 128.675 1.00 74.13 ? 52  GLN B CB  1 
ATOM   2210 N N   . MET B 2 53  ? 103.457 121.821 126.912 1.00 75.84 ? 53  MET B N   1 
ATOM   2211 C CA  . MET B 2 53  ? 104.167 123.047 126.571 1.00 77.03 ? 53  MET B CA  1 
ATOM   2212 C C   . MET B 2 53  ? 105.055 122.796 125.360 1.00 77.67 ? 53  MET B C   1 
ATOM   2213 O O   . MET B 2 53  ? 105.795 121.808 125.321 1.00 71.43 ? 53  MET B O   1 
ATOM   2214 C CB  . MET B 2 53  ? 105.010 123.531 127.751 1.00 73.08 ? 53  MET B CB  1 
ATOM   2215 C CG  . MET B 2 53  ? 104.212 123.758 129.023 1.00 74.10 ? 53  MET B CG  1 
ATOM   2216 S SD  . MET B 2 53  ? 104.235 122.329 130.121 1.00 75.61 ? 53  MET B SD  1 
ATOM   2217 C CE  . MET B 2 53  ? 105.685 122.684 131.108 1.00 68.41 ? 53  MET B CE  1 
ATOM   2218 N N   . ARG B 2 54  ? 104.975 123.687 124.377 1.00 90.14 ? 54  ARG B N   1 
ATOM   2219 C CA  . ARG B 2 54  ? 105.805 123.586 123.184 1.00 88.88 ? 54  ARG B CA  1 
ATOM   2220 C C   . ARG B 2 54  ? 105.777 124.905 122.416 1.00 86.77 ? 54  ARG B C   1 
ATOM   2221 O O   . ARG B 2 54  ? 104.849 125.700 122.559 1.00 87.46 ? 54  ARG B O   1 
ATOM   2222 C CB  . ARG B 2 54  ? 105.330 122.429 122.296 1.00 87.31 ? 54  ARG B CB  1 
ATOM   2223 C CG  . ARG B 2 54  ? 105.763 122.530 120.831 1.00 88.60 ? 54  ARG B CG  1 
ATOM   2224 C CD  . ARG B 2 54  ? 105.737 121.183 120.122 1.00 87.14 ? 54  ARG B CD  1 
ATOM   2225 N NE  . ARG B 2 54  ? 106.545 121.198 118.907 1.00 88.72 ? 54  ARG B NE  1 
ATOM   2226 C CZ  . ARG B 2 54  ? 107.862 121.030 118.862 1.00 87.25 ? 54  ARG B CZ  1 
ATOM   2227 N NH1 . ARG B 2 54  ? 108.581 120.846 119.959 1.00 86.19 ? 54  ARG B NH1 1 
ATOM   2228 N NH2 . ARG B 2 54  ? 108.477 121.053 117.683 1.00 87.45 ? 54  ARG B NH2 1 
ATOM   2229 N N   . THR B 2 66  ? 115.098 123.166 108.383 1.00 79.41 ? 66  THR B N   1 
ATOM   2230 C CA  . THR B 2 66  ? 115.685 122.958 109.702 1.00 81.52 ? 66  THR B CA  1 
ATOM   2231 C C   . THR B 2 66  ? 115.652 121.480 110.075 1.00 79.07 ? 66  THR B C   1 
ATOM   2232 O O   . THR B 2 66  ? 115.348 121.122 111.212 1.00 79.91 ? 66  THR B O   1 
ATOM   2233 C CB  . THR B 2 66  ? 114.948 123.775 110.784 1.00 82.80 ? 66  THR B CB  1 
ATOM   2234 O OG1 . THR B 2 66  ? 113.589 123.331 110.886 1.00 83.16 ? 66  THR B OG1 1 
ATOM   2235 C CG2 . THR B 2 66  ? 114.971 125.258 110.444 1.00 79.17 ? 66  THR B CG2 1 
ATOM   2236 N N   . SER B 2 67  ? 115.967 120.621 109.104 1.00 71.36 ? 67  SER B N   1 
ATOM   2237 C CA  . SER B 2 67  ? 115.942 119.184 109.352 1.00 73.45 ? 67  SER B CA  1 
ATOM   2238 C C   . SER B 2 67  ? 117.053 118.753 110.301 1.00 73.32 ? 67  SER B C   1 
ATOM   2239 O O   . SER B 2 67  ? 116.874 117.801 111.070 1.00 69.23 ? 67  SER B O   1 
ATOM   2240 C CB  . SER B 2 67  ? 116.055 118.425 108.030 1.00 72.81 ? 67  SER B CB  1 
ATOM   2241 O OG  . SER B 2 67  ? 117.287 118.702 107.387 1.00 71.89 ? 67  SER B OG  1 
ATOM   2242 N N   . GLY B 2 68  ? 118.202 119.430 110.258 1.00 72.10 ? 68  GLY B N   1 
ATOM   2243 C CA  . GLY B 2 68  ? 119.334 119.002 111.064 1.00 72.28 ? 68  GLY B CA  1 
ATOM   2244 C C   . GLY B 2 68  ? 119.095 119.133 112.556 1.00 74.37 ? 68  GLY B C   1 
ATOM   2245 O O   . GLY B 2 68  ? 119.576 118.312 113.342 1.00 73.47 ? 68  GLY B O   1 
ATOM   2246 N N   . ILE B 2 69  ? 118.355 120.163 112.967 1.00 71.00 ? 69  ILE B N   1 
ATOM   2247 C CA  . ILE B 2 69  ? 118.166 120.506 114.372 1.00 69.09 ? 69  ILE B CA  1 
ATOM   2248 C C   . ILE B 2 69  ? 116.675 120.610 114.660 1.00 68.43 ? 69  ILE B C   1 
ATOM   2249 O O   . ILE B 2 69  ? 115.909 121.135 113.845 1.00 69.81 ? 69  ILE B O   1 
ATOM   2250 C CB  . ILE B 2 69  ? 118.892 121.824 114.726 1.00 68.27 ? 69  ILE B CB  1 
ATOM   2251 C CG1 . ILE B 2 69  ? 118.978 122.023 116.243 1.00 65.75 ? 69  ILE B CG1 1 
ATOM   2252 C CG2 . ILE B 2 69  ? 118.195 123.021 114.083 1.00 69.40 ? 69  ILE B CG2 1 
ATOM   2253 C CD1 . ILE B 2 69  ? 120.001 121.144 116.923 1.00 64.40 ? 69  ILE B CD1 1 
ATOM   2254 N N   . PHE B 2 70  ? 116.268 120.092 115.819 1.00 61.98 ? 70  PHE B N   1 
ATOM   2255 C CA  . PHE B 2 70  ? 114.914 120.238 116.336 1.00 62.97 ? 70  PHE B CA  1 
ATOM   2256 C C   . PHE B 2 70  ? 114.985 120.965 117.669 1.00 62.74 ? 70  PHE B C   1 
ATOM   2257 O O   . PHE B 2 70  ? 115.855 120.675 118.495 1.00 64.45 ? 70  PHE B O   1 
ATOM   2258 C CB  . PHE B 2 70  ? 114.227 118.879 116.507 1.00 58.42 ? 70  PHE B CB  1 
ATOM   2259 N N   . GLU B 2 71  ? 114.068 121.909 117.872 1.00 63.89 ? 71  GLU B N   1 
ATOM   2260 C CA  . GLU B 2 71  ? 114.079 122.798 119.026 1.00 60.88 ? 71  GLU B CA  1 
ATOM   2261 C C   . GLU B 2 71  ? 112.746 122.708 119.749 1.00 64.70 ? 71  GLU B C   1 
ATOM   2262 O O   . GLU B 2 71  ? 111.704 122.490 119.124 1.00 66.10 ? 71  GLU B O   1 
ATOM   2263 C CB  . GLU B 2 71  ? 114.344 124.262 118.618 1.00 64.37 ? 71  GLU B CB  1 
ATOM   2264 C CG  . GLU B 2 71  ? 115.546 124.491 117.692 1.00 65.13 ? 71  GLU B CG  1 
ATOM   2265 C CD  . GLU B 2 71  ? 115.416 125.763 116.874 1.00 65.27 ? 71  GLU B CD  1 
ATOM   2266 O OE1 . GLU B 2 71  ? 116.284 126.651 117.007 1.00 64.01 ? 71  GLU B OE1 1 
ATOM   2267 O OE2 . GLU B 2 71  ? 114.446 125.873 116.095 1.00 61.19 ? 71  GLU B OE2 1 
ATOM   2268 N N   . THR B 2 72  ? 112.787 122.871 121.069 1.00 66.13 ? 72  THR B N   1 
ATOM   2269 C CA  . THR B 2 72  ? 111.586 122.889 121.893 1.00 64.66 ? 72  THR B CA  1 
ATOM   2270 C C   . THR B 2 72  ? 111.840 123.793 123.088 1.00 64.34 ? 72  THR B C   1 
ATOM   2271 O O   . THR B 2 72  ? 112.863 123.656 123.765 1.00 64.32 ? 72  THR B O   1 
ATOM   2272 C CB  . THR B 2 72  ? 111.204 121.477 122.356 1.00 61.28 ? 72  THR B CB  1 
ATOM   2273 O OG1 . THR B 2 72  ? 110.661 120.744 121.251 1.00 66.49 ? 72  THR B OG1 1 
ATOM   2274 C CG2 . THR B 2 72  ? 110.169 121.523 123.476 1.00 62.75 ? 72  THR B CG2 1 
ATOM   2275 N N   . LYS B 2 73  ? 110.910 124.710 123.338 1.00 64.55 ? 73  LYS B N   1 
ATOM   2276 C CA  . LYS B 2 73  ? 111.020 125.693 124.407 1.00 64.26 ? 73  LYS B CA  1 
ATOM   2277 C C   . LYS B 2 73  ? 109.814 125.571 125.325 1.00 63.93 ? 73  LYS B C   1 
ATOM   2278 O O   . LYS B 2 73  ? 108.669 125.634 124.865 1.00 67.22 ? 73  LYS B O   1 
ATOM   2279 C CB  . LYS B 2 73  ? 111.106 127.111 123.838 1.00 62.42 ? 73  LYS B CB  1 
ATOM   2280 C CG  . LYS B 2 73  ? 111.920 127.220 122.554 1.00 61.41 ? 73  LYS B CG  1 
ATOM   2281 C CD  . LYS B 2 73  ? 112.544 128.596 122.394 1.00 61.92 ? 73  LYS B CD  1 
ATOM   2282 C CE  . LYS B 2 73  ? 113.505 128.635 121.218 1.00 61.51 ? 73  LYS B CE  1 
ATOM   2283 N NZ  . LYS B 2 73  ? 112.808 128.377 119.928 1.00 59.86 ? 73  LYS B NZ  1 
ATOM   2284 N N   . PHE B 2 74  ? 110.074 125.394 126.619 1.00 55.72 ? 74  PHE B N   1 
ATOM   2285 C CA  . PHE B 2 74  ? 109.025 125.296 127.621 1.00 57.49 ? 74  PHE B CA  1 
ATOM   2286 C C   . PHE B 2 74  ? 109.491 125.976 128.899 1.00 57.47 ? 74  PHE B C   1 
ATOM   2287 O O   . PHE B 2 74  ? 110.691 126.058 129.174 1.00 56.59 ? 74  PHE B O   1 
ATOM   2288 C CB  . PHE B 2 74  ? 108.638 123.829 127.880 1.00 57.54 ? 74  PHE B CB  1 
ATOM   2289 C CG  . PHE B 2 74  ? 109.682 123.038 128.616 1.00 54.20 ? 74  PHE B CG  1 
ATOM   2290 C CD1 . PHE B 2 74  ? 110.747 122.474 127.936 1.00 53.72 ? 74  PHE B CD1 1 
ATOM   2291 C CD2 . PHE B 2 74  ? 109.590 122.840 129.982 1.00 53.25 ? 74  PHE B CD2 1 
ATOM   2292 C CE1 . PHE B 2 74  ? 111.704 121.739 128.607 1.00 52.65 ? 74  PHE B CE1 1 
ATOM   2293 C CE2 . PHE B 2 74  ? 110.546 122.107 130.656 1.00 53.56 ? 74  PHE B CE2 1 
ATOM   2294 C CZ  . PHE B 2 74  ? 111.602 121.556 129.968 1.00 52.55 ? 74  PHE B CZ  1 
ATOM   2295 N N   . GLN B 2 75  ? 108.524 126.469 129.671 1.00 59.28 ? 75  GLN B N   1 
ATOM   2296 C CA  . GLN B 2 75  ? 108.776 127.219 130.894 1.00 55.84 ? 75  GLN B CA  1 
ATOM   2297 C C   . GLN B 2 75  ? 108.065 126.543 132.055 1.00 58.68 ? 75  GLN B C   1 
ATOM   2298 O O   . GLN B 2 75  ? 106.939 126.057 131.899 1.00 61.21 ? 75  GLN B O   1 
ATOM   2299 C CB  . GLN B 2 75  ? 108.292 128.667 130.766 1.00 57.33 ? 75  GLN B CB  1 
ATOM   2300 C CG  . GLN B 2 75  ? 108.369 129.464 132.066 1.00 59.74 ? 75  GLN B CG  1 
ATOM   2301 C CD  . GLN B 2 75  ? 108.506 130.958 131.843 1.00 62.09 ? 75  GLN B CD  1 
ATOM   2302 O OE1 . GLN B 2 75  ? 109.594 131.462 131.571 1.00 55.95 ? 75  GLN B OE1 1 
ATOM   2303 N NE2 . GLN B 2 75  ? 107.396 131.678 131.973 1.00 64.77 ? 75  GLN B NE2 1 
ATOM   2304 N N   . VAL B 2 76  ? 108.723 126.508 133.210 1.00 54.05 ? 76  VAL B N   1 
ATOM   2305 C CA  . VAL B 2 76  ? 108.103 126.065 134.454 1.00 55.59 ? 76  VAL B CA  1 
ATOM   2306 C C   . VAL B 2 76  ? 108.637 126.935 135.585 1.00 54.46 ? 76  VAL B C   1 
ATOM   2307 O O   . VAL B 2 76  ? 109.850 127.003 135.808 1.00 52.10 ? 76  VAL B O   1 
ATOM   2308 C CB  . VAL B 2 76  ? 108.349 124.566 134.733 1.00 51.96 ? 76  VAL B CB  1 
ATOM   2309 C CG1 . VAL B 2 76  ? 109.837 124.241 134.860 1.00 51.38 ? 76  VAL B CG1 1 
ATOM   2310 C CG2 . VAL B 2 76  ? 107.595 124.132 135.981 1.00 51.42 ? 76  VAL B CG2 1 
ATOM   2311 N N   . ASP B 2 77  ? 107.724 127.609 136.286 1.00 53.43 ? 77  ASP B N   1 
ATOM   2312 C CA  . ASP B 2 77  ? 108.056 128.510 137.392 1.00 53.17 ? 77  ASP B CA  1 
ATOM   2313 C C   . ASP B 2 77  ? 109.049 129.567 136.888 1.00 55.41 ? 77  ASP B C   1 
ATOM   2314 O O   . ASP B 2 77  ? 110.150 129.738 137.414 1.00 53.99 ? 77  ASP B O   1 
ATOM   2315 C CB  . ASP B 2 77  ? 108.583 127.696 138.592 1.00 53.91 ? 77  ASP B CB  1 
ATOM   2316 C CG  . ASP B 2 77  ? 109.092 128.548 139.770 1.00 57.12 ? 77  ASP B CG  1 
ATOM   2317 O OD1 . ASP B 2 77  ? 109.000 129.792 139.751 1.00 60.31 ? 77  ASP B OD1 1 
ATOM   2318 O OD2 . ASP B 2 77  ? 109.502 127.938 140.782 1.00 56.49 ? 77  ASP B OD2 1 
ATOM   2319 N N   . LYS B 2 78  ? 108.684 130.224 135.787 1.00 60.69 ? 78  LYS B N   1 
ATOM   2320 C CA  . LYS B 2 78  ? 109.418 131.383 135.286 1.00 62.82 ? 78  LYS B CA  1 
ATOM   2321 C C   . LYS B 2 78  ? 110.837 131.068 134.813 1.00 65.53 ? 78  LYS B C   1 
ATOM   2322 O O   . LYS B 2 78  ? 111.626 131.995 134.602 1.00 65.49 ? 78  LYS B O   1 
ATOM   2323 C CB  . LYS B 2 78  ? 109.475 132.462 136.369 1.00 56.85 ? 78  LYS B CB  1 
ATOM   2324 N N   . VAL B 2 79  ? 111.175 129.787 134.645 1.00 61.25 ? 79  VAL B N   1 
ATOM   2325 C CA  . VAL B 2 79  ? 112.499 129.386 134.170 1.00 56.56 ? 79  VAL B CA  1 
ATOM   2326 C C   . VAL B 2 79  ? 112.367 128.809 132.767 1.00 57.31 ? 79  VAL B C   1 
ATOM   2327 O O   . VAL B 2 79  ? 111.557 127.907 132.530 1.00 51.47 ? 79  VAL B O   1 
ATOM   2328 C CB  . VAL B 2 79  ? 113.140 128.366 135.127 1.00 51.32 ? 79  VAL B CB  1 
ATOM   2329 C CG1 . VAL B 2 79  ? 114.619 128.184 134.802 1.00 53.31 ? 79  VAL B CG1 1 
ATOM   2330 C CG2 . VAL B 2 79  ? 112.962 128.795 136.573 1.00 53.60 ? 79  VAL B CG2 1 
ATOM   2331 N N   . ASN B 2 80  ? 113.178 129.315 131.840 1.00 57.14 ? 80  ASN B N   1 
ATOM   2332 C CA  . ASN B 2 80  ? 113.140 128.904 130.442 1.00 51.72 ? 80  ASN B CA  1 
ATOM   2333 C C   . ASN B 2 80  ? 114.101 127.746 130.202 1.00 51.56 ? 80  ASN B C   1 
ATOM   2334 O O   . ASN B 2 80  ? 115.249 127.782 130.657 1.00 59.49 ? 80  ASN B O   1 
ATOM   2335 C CB  . ASN B 2 80  ? 113.504 130.070 129.521 1.00 53.47 ? 80  ASN B CB  1 
ATOM   2336 C CG  . ASN B 2 80  ? 112.605 131.271 129.709 1.00 55.40 ? 80  ASN B CG  1 
ATOM   2337 O OD1 . ASN B 2 80  ? 111.383 131.160 129.641 1.00 56.70 ? 80  ASN B OD1 1 
ATOM   2338 N ND2 . ASN B 2 80  ? 113.207 132.433 129.940 1.00 53.31 ? 80  ASN B ND2 1 
ATOM   2339 N N   . PHE B 2 81  ? 113.628 126.728 129.482 1.00 44.44 ? 81  PHE B N   1 
ATOM   2340 C CA  . PHE B 2 81  ? 114.436 125.591 129.060 1.00 47.58 ? 81  PHE B CA  1 
ATOM   2341 C C   . PHE B 2 81  ? 114.389 125.480 127.543 1.00 49.13 ? 81  PHE B C   1 
ATOM   2342 O O   . PHE B 2 81  ? 113.310 125.555 126.949 1.00 50.09 ? 81  PHE B O   1 
ATOM   2343 C CB  . PHE B 2 81  ? 113.928 124.283 129.678 1.00 52.17 ? 81  PHE B CB  1 
ATOM   2344 C CG  . PHE B 2 81  ? 114.133 124.184 131.162 1.00 48.83 ? 81  PHE B CG  1 
ATOM   2345 C CD1 . PHE B 2 81  ? 115.357 123.811 131.683 1.00 47.90 ? 81  PHE B CD1 1 
ATOM   2346 C CD2 . PHE B 2 81  ? 113.092 124.444 132.035 1.00 50.40 ? 81  PHE B CD2 1 
ATOM   2347 C CE1 . PHE B 2 81  ? 115.542 123.712 133.046 1.00 49.09 ? 81  PHE B CE1 1 
ATOM   2348 C CE2 . PHE B 2 81  ? 113.273 124.347 133.397 1.00 48.29 ? 81  PHE B CE2 1 
ATOM   2349 C CZ  . PHE B 2 81  ? 114.499 123.981 133.903 1.00 46.64 ? 81  PHE B CZ  1 
ATOM   2350 N N   . HIS B 2 82  ? 115.555 125.307 126.923 1.00 51.45 ? 82  HIS B N   1 
ATOM   2351 C CA  . HIS B 2 82  ? 115.667 124.933 125.517 1.00 49.86 ? 82  HIS B CA  1 
ATOM   2352 C C   . HIS B 2 82  ? 116.141 123.491 125.432 1.00 48.63 ? 82  HIS B C   1 
ATOM   2353 O O   . HIS B 2 82  ? 117.266 123.178 125.835 1.00 52.34 ? 82  HIS B O   1 
ATOM   2354 C CB  . HIS B 2 82  ? 116.635 125.838 124.745 1.00 53.36 ? 82  HIS B CB  1 
ATOM   2355 C CG  . HIS B 2 82  ? 116.280 127.293 124.777 1.00 60.63 ? 82  HIS B CG  1 
ATOM   2356 N ND1 . HIS B 2 82  ? 116.127 127.992 125.956 1.00 62.36 ? 82  HIS B ND1 1 
ATOM   2357 C CD2 . HIS B 2 82  ? 116.034 128.177 123.784 1.00 57.14 ? 82  HIS B CD2 1 
ATOM   2358 C CE1 . HIS B 2 82  ? 115.810 129.246 125.684 1.00 54.14 ? 82  HIS B CE1 1 
ATOM   2359 N NE2 . HIS B 2 82  ? 115.748 129.385 124.373 1.00 55.93 ? 82  HIS B NE2 1 
ATOM   2360 N N   . MET B 2 83  ? 115.282 122.622 124.907 1.00 45.89 ? 83  MET B N   1 
ATOM   2361 C CA  . MET B 2 83  ? 115.573 121.205 124.751 1.00 48.06 ? 83  MET B CA  1 
ATOM   2362 C C   . MET B 2 83  ? 115.894 120.941 123.289 1.00 48.10 ? 83  MET B C   1 
ATOM   2363 O O   . MET B 2 83  ? 115.065 121.204 122.413 1.00 54.69 ? 83  MET B O   1 
ATOM   2364 C CB  . MET B 2 83  ? 114.385 120.359 125.210 1.00 50.51 ? 83  MET B CB  1 
ATOM   2365 C CG  . MET B 2 83  ? 114.563 118.859 124.997 1.00 48.09 ? 83  MET B CG  1 
ATOM   2366 S SD  . MET B 2 83  ? 113.477 117.725 125.912 1.00 54.33 ? 83  MET B SD  1 
ATOM   2367 C CE  . MET B 2 83  ? 112.393 118.785 126.870 1.00 47.18 ? 83  MET B CE  1 
ATOM   2368 N N   . PHE B 2 84  ? 117.089 120.416 123.034 1.00 46.85 ? 84  PHE B N   1 
ATOM   2369 C CA  . PHE B 2 84  ? 117.624 120.275 121.687 1.00 50.37 ? 84  PHE B CA  1 
ATOM   2370 C C   . PHE B 2 84  ? 117.644 118.804 121.301 1.00 49.89 ? 84  PHE B C   1 
ATOM   2371 O O   . PHE B 2 84  ? 118.299 117.993 121.965 1.00 58.73 ? 84  PHE B O   1 
ATOM   2372 C CB  . PHE B 2 84  ? 119.039 120.861 121.607 1.00 40.27 ? 84  PHE B CB  1 
ATOM   2373 C CG  . PHE B 2 84  ? 119.083 122.371 121.598 1.00 43.97 ? 84  PHE B CG  1 
ATOM   2374 C CD1 . PHE B 2 84  ? 118.307 123.115 120.719 1.00 53.06 ? 84  PHE B CD1 1 
ATOM   2375 C CD2 . PHE B 2 84  ? 119.897 123.046 122.490 1.00 47.13 ? 84  PHE B CD2 1 
ATOM   2376 C CE1 . PHE B 2 84  ? 118.351 124.495 120.727 1.00 56.05 ? 84  PHE B CE1 1 
ATOM   2377 C CE2 . PHE B 2 84  ? 119.942 124.428 122.500 1.00 52.39 ? 84  PHE B CE2 1 
ATOM   2378 C CZ  . PHE B 2 84  ? 119.169 125.150 121.618 1.00 53.50 ? 84  PHE B CZ  1 
ATOM   2379 N N   . ASP B 2 85  ? 116.928 118.469 120.230 1.00 46.81 ? 85  ASP B N   1 
ATOM   2380 C CA  . ASP B 2 85  ? 116.881 117.118 119.687 1.00 48.65 ? 85  ASP B CA  1 
ATOM   2381 C C   . ASP B 2 85  ? 117.353 117.162 118.243 1.00 54.03 ? 85  ASP B C   1 
ATOM   2382 O O   . ASP B 2 85  ? 116.950 118.049 117.484 1.00 60.07 ? 85  ASP B O   1 
ATOM   2383 C CB  . ASP B 2 85  ? 115.467 116.536 119.766 1.00 51.04 ? 85  ASP B CB  1 
ATOM   2384 C CG  . ASP B 2 85  ? 115.345 115.205 119.053 1.00 53.78 ? 85  ASP B CG  1 
ATOM   2385 O OD1 . ASP B 2 85  ? 116.344 114.456 119.010 1.00 52.95 ? 85  ASP B OD1 1 
ATOM   2386 O OD2 . ASP B 2 85  ? 114.248 114.905 118.536 1.00 52.46 ? 85  ASP B OD2 1 
ATOM   2387 N N   . VAL B 2 86  ? 118.206 116.210 117.872 1.00 60.89 ? 86  VAL B N   1 
ATOM   2388 C CA  . VAL B 2 86  ? 118.762 116.109 116.526 1.00 63.29 ? 86  VAL B CA  1 
ATOM   2389 C C   . VAL B 2 86  ? 118.329 114.771 115.946 1.00 64.25 ? 86  VAL B C   1 
ATOM   2390 O O   . VAL B 2 86  ? 118.658 113.714 116.501 1.00 69.35 ? 86  VAL B O   1 
ATOM   2391 C CB  . VAL B 2 86  ? 120.294 116.238 116.534 1.00 64.15 ? 86  VAL B CB  1 
ATOM   2392 C CG1 . VAL B 2 86  ? 120.875 115.844 115.188 1.00 62.84 ? 86  VAL B CG1 1 
ATOM   2393 C CG2 . VAL B 2 86  ? 120.708 117.655 116.891 1.00 60.98 ? 86  VAL B CG2 1 
ATOM   2394 N N   . GLY B 2 87  ? 117.597 114.818 114.833 1.00 60.54 ? 87  GLY B N   1 
ATOM   2395 C CA  . GLY B 2 87  ? 117.111 113.625 114.162 1.00 59.78 ? 87  GLY B CA  1 
ATOM   2396 C C   . GLY B 2 87  ? 117.608 113.461 112.738 1.00 60.66 ? 87  GLY B C   1 
ATOM   2397 O O   . GLY B 2 87  ? 117.284 112.464 112.086 1.00 57.54 ? 87  GLY B O   1 
ATOM   2398 N N   . GLY B 2 88  ? 118.389 114.419 112.243 1.00 69.13 ? 88  GLY B N   1 
ATOM   2399 C CA  . GLY B 2 88  ? 118.899 114.400 110.888 1.00 67.73 ? 88  GLY B CA  1 
ATOM   2400 C C   . GLY B 2 88  ? 120.312 113.881 110.732 1.00 66.41 ? 88  GLY B C   1 
ATOM   2401 O O   . GLY B 2 88  ? 120.916 114.102 109.676 1.00 66.62 ? 88  GLY B O   1 
ATOM   2402 N N   . GLN B 2 89  ? 120.856 113.199 111.737 1.00 69.90 ? 89  GLN B N   1 
ATOM   2403 C CA  . GLN B 2 89  ? 122.224 112.700 111.727 1.00 70.44 ? 89  GLN B CA  1 
ATOM   2404 C C   . GLN B 2 89  ? 122.233 111.182 111.613 1.00 71.56 ? 89  GLN B C   1 
ATOM   2405 O O   . GLN B 2 89  ? 121.206 110.510 111.745 1.00 72.45 ? 89  GLN B O   1 
ATOM   2406 C CB  . GLN B 2 89  ? 122.971 113.145 112.991 1.00 68.18 ? 89  GLN B CB  1 
ATOM   2407 C CG  . GLN B 2 89  ? 123.214 114.645 113.081 1.00 69.95 ? 89  GLN B CG  1 
ATOM   2408 C CD  . GLN B 2 89  ? 124.127 115.166 111.989 1.00 69.26 ? 89  GLN B CD  1 
ATOM   2409 O OE1 . GLN B 2 89  ? 125.132 114.541 111.652 1.00 70.95 ? 89  GLN B OE1 1 
ATOM   2410 N NE2 . GLN B 2 89  ? 123.778 116.317 111.427 1.00 66.64 ? 89  GLN B NE2 1 
ATOM   2411 N N   . ARG B 2 90  ? 123.424 110.648 111.364 1.00 76.30 ? 90  ARG B N   1 
ATOM   2412 C CA  . ARG B 2 90  ? 123.625 109.221 111.182 1.00 74.73 ? 90  ARG B CA  1 
ATOM   2413 C C   . ARG B 2 90  ? 123.716 108.546 112.550 1.00 76.00 ? 90  ARG B C   1 
ATOM   2414 O O   . ARG B 2 90  ? 123.538 109.179 113.594 1.00 74.09 ? 90  ARG B O   1 
ATOM   2415 C CB  . ARG B 2 90  ? 124.871 108.988 110.330 1.00 74.79 ? 90  ARG B CB  1 
ATOM   2416 C CG  . ARG B 2 90  ? 124.820 109.719 108.996 1.00 78.46 ? 90  ARG B CG  1 
ATOM   2417 C CD  . ARG B 2 90  ? 125.601 109.013 107.899 1.00 77.79 ? 90  ARG B CD  1 
ATOM   2418 N NE  . ARG B 2 90  ? 127.028 108.951 108.194 1.00 74.35 ? 90  ARG B NE  1 
ATOM   2419 C CZ  . ARG B 2 90  ? 127.935 108.352 107.433 1.00 74.74 ? 90  ARG B CZ  1 
ATOM   2420 N NH1 . ARG B 2 90  ? 127.610 107.759 106.295 1.00 73.62 ? 90  ARG B NH1 1 
ATOM   2421 N NH2 . ARG B 2 90  ? 129.208 108.356 107.820 1.00 76.61 ? 90  ARG B NH2 1 
ATOM   2422 N N   . ASP B 2 91  ? 123.996 107.241 112.559 1.00 74.92 ? 91  ASP B N   1 
ATOM   2423 C CA  . ASP B 2 91  ? 124.106 106.519 113.821 1.00 74.71 ? 91  ASP B CA  1 
ATOM   2424 C C   . ASP B 2 91  ? 125.354 106.924 114.597 1.00 70.24 ? 91  ASP B C   1 
ATOM   2425 O O   . ASP B 2 91  ? 125.345 106.909 115.833 1.00 65.32 ? 91  ASP B O   1 
ATOM   2426 C CB  . ASP B 2 91  ? 124.109 105.013 113.561 1.00 72.50 ? 91  ASP B CB  1 
ATOM   2427 N N   . GLU B 2 92  ? 126.425 107.285 113.897 1.00 74.93 ? 92  GLU B N   1 
ATOM   2428 C CA  . GLU B 2 92  ? 127.691 107.645 114.523 1.00 74.89 ? 92  GLU B CA  1 
ATOM   2429 C C   . GLU B 2 92  ? 127.666 109.134 114.848 1.00 75.52 ? 92  GLU B C   1 
ATOM   2430 O O   . GLU B 2 92  ? 127.605 109.968 113.938 1.00 74.97 ? 92  GLU B O   1 
ATOM   2431 C CB  . GLU B 2 92  ? 128.847 107.291 113.583 1.00 74.64 ? 92  GLU B CB  1 
ATOM   2432 C CG  . GLU B 2 92  ? 130.207 107.955 113.825 1.00 74.35 ? 92  GLU B CG  1 
ATOM   2433 C CD  . GLU B 2 92  ? 130.683 107.964 115.270 1.00 73.26 ? 92  GLU B CD  1 
ATOM   2434 O OE1 . GLU B 2 92  ? 130.080 107.303 116.141 1.00 66.10 ? 92  GLU B OE1 1 
ATOM   2435 O OE2 . GLU B 2 92  ? 131.713 108.614 115.523 1.00 73.06 ? 92  GLU B OE2 1 
ATOM   2436 N N   . ARG B 2 93  ? 127.719 109.465 116.144 1.00 64.51 ? 93  ARG B N   1 
ATOM   2437 C CA  . ARG B 2 93  ? 127.496 110.825 116.628 1.00 61.44 ? 93  ARG B CA  1 
ATOM   2438 C C   . ARG B 2 93  ? 128.684 111.372 117.415 1.00 59.16 ? 93  ARG B C   1 
ATOM   2439 O O   . ARG B 2 93  ? 128.516 112.266 118.243 1.00 57.56 ? 93  ARG B O   1 
ATOM   2440 C CB  . ARG B 2 93  ? 126.230 110.887 117.489 1.00 57.65 ? 93  ARG B CB  1 
ATOM   2441 C CG  . ARG B 2 93  ? 126.257 110.021 118.767 1.00 57.97 ? 93  ARG B CG  1 
ATOM   2442 C CD  . ARG B 2 93  ? 125.214 110.460 119.805 1.00 59.46 ? 93  ARG B CD  1 
ATOM   2443 N NE  . ARG B 2 93  ? 123.937 109.764 119.675 1.00 59.11 ? 93  ARG B NE  1 
ATOM   2444 C CZ  . ARG B 2 93  ? 123.578 108.674 120.346 1.00 59.01 ? 93  ARG B CZ  1 
ATOM   2445 N NH1 . ARG B 2 93  ? 124.392 108.077 121.205 1.00 57.19 ? 93  ARG B NH1 1 
ATOM   2446 N NH2 . ARG B 2 93  ? 122.366 108.164 120.149 1.00 59.73 ? 93  ARG B NH2 1 
ATOM   2447 N N   . ARG B 2 94  ? 129.892 110.868 117.173 1.00 61.88 ? 94  ARG B N   1 
ATOM   2448 C CA  . ARG B 2 94  ? 131.027 111.266 117.997 1.00 62.91 ? 94  ARG B CA  1 
ATOM   2449 C C   . ARG B 2 94  ? 131.590 112.635 117.635 1.00 61.31 ? 94  ARG B C   1 
ATOM   2450 O O   . ARG B 2 94  ? 132.419 113.151 118.392 1.00 63.86 ? 94  ARG B O   1 
ATOM   2451 C CB  . ARG B 2 94  ? 132.144 110.225 117.901 1.00 64.48 ? 94  ARG B CB  1 
ATOM   2452 N N   . LYS B 2 95  ? 131.166 113.236 116.523 1.00 52.43 ? 95  LYS B N   1 
ATOM   2453 C CA  . LYS B 2 95  ? 131.746 114.483 116.031 1.00 56.30 ? 95  LYS B CA  1 
ATOM   2454 C C   . LYS B 2 95  ? 130.875 115.707 116.262 1.00 58.37 ? 95  LYS B C   1 
ATOM   2455 O O   . LYS B 2 95  ? 131.410 116.785 116.523 1.00 58.00 ? 95  LYS B O   1 
ATOM   2456 C CB  . LYS B 2 95  ? 132.056 114.362 114.533 1.00 52.90 ? 95  LYS B CB  1 
ATOM   2457 C CG  . LYS B 2 95  ? 133.262 113.480 114.177 1.00 54.69 ? 95  LYS B CG  1 
ATOM   2458 C CD  . LYS B 2 95  ? 134.581 114.010 114.749 1.00 51.48 ? 95  LYS B CD  1 
ATOM   2459 C CE  . LYS B 2 95  ? 135.766 113.181 114.295 1.00 53.24 ? 95  LYS B CE  1 
ATOM   2460 N NZ  . LYS B 2 95  ? 137.039 113.621 114.932 1.00 49.54 ? 95  LYS B NZ  1 
ATOM   2461 N N   . TRP B 2 96  ? 129.553 115.584 116.174 1.00 55.18 ? 96  TRP B N   1 
ATOM   2462 C CA  . TRP B 2 96  ? 128.660 116.698 116.466 1.00 55.60 ? 96  TRP B CA  1 
ATOM   2463 C C   . TRP B 2 96  ? 128.254 116.768 117.936 1.00 60.09 ? 96  TRP B C   1 
ATOM   2464 O O   . TRP B 2 96  ? 127.505 117.674 118.310 1.00 62.33 ? 96  TRP B O   1 
ATOM   2465 C CB  . TRP B 2 96  ? 127.411 116.631 115.580 1.00 56.08 ? 96  TRP B CB  1 
ATOM   2466 C CG  . TRP B 2 96  ? 126.509 115.473 115.850 1.00 56.87 ? 96  TRP B CG  1 
ATOM   2467 C CD1 . TRP B 2 96  ? 126.579 114.236 115.284 1.00 61.48 ? 96  TRP B CD1 1 
ATOM   2468 C CD2 . TRP B 2 96  ? 125.393 115.442 116.747 1.00 57.88 ? 96  TRP B CD2 1 
ATOM   2469 N NE1 . TRP B 2 96  ? 125.575 113.436 115.770 1.00 64.48 ? 96  TRP B NE1 1 
ATOM   2470 C CE2 . TRP B 2 96  ? 124.835 114.152 116.673 1.00 62.28 ? 96  TRP B CE2 1 
ATOM   2471 C CE3 . TRP B 2 96  ? 124.812 116.378 117.606 1.00 57.10 ? 96  TRP B CE3 1 
ATOM   2472 C CZ2 . TRP B 2 96  ? 123.727 113.773 117.426 1.00 59.03 ? 96  TRP B CZ2 1 
ATOM   2473 C CZ3 . TRP B 2 96  ? 123.711 116.001 118.353 1.00 59.16 ? 96  TRP B CZ3 1 
ATOM   2474 C CH2 . TRP B 2 96  ? 123.181 114.709 118.258 1.00 58.41 ? 96  TRP B CH2 1 
ATOM   2475 N N   . ILE B 2 97  ? 128.736 115.844 118.775 1.00 58.90 ? 97  ILE B N   1 
ATOM   2476 C CA  . ILE B 2 97  ? 128.454 115.879 120.209 1.00 51.97 ? 97  ILE B CA  1 
ATOM   2477 C C   . ILE B 2 97  ? 129.461 116.713 120.991 1.00 49.96 ? 97  ILE B C   1 
ATOM   2478 O O   . ILE B 2 97  ? 129.210 117.016 122.168 1.00 53.16 ? 97  ILE B O   1 
ATOM   2479 C CB  . ILE B 2 97  ? 128.379 114.445 120.789 1.00 55.09 ? 97  ILE B CB  1 
ATOM   2480 C CG1 . ILE B 2 97  ? 127.314 114.346 121.888 1.00 52.33 ? 97  ILE B CG1 1 
ATOM   2481 C CG2 . ILE B 2 97  ? 129.745 113.943 121.294 1.00 60.80 ? 97  ILE B CG2 1 
ATOM   2482 C CD1 . ILE B 2 97  ? 125.884 114.406 121.387 1.00 54.30 ? 97  ILE B CD1 1 
ATOM   2483 N N   . GLN B 2 98  ? 130.590 117.092 120.385 1.00 50.04 ? 98  GLN B N   1 
ATOM   2484 C CA  . GLN B 2 98  ? 131.532 117.965 121.078 1.00 55.32 ? 98  GLN B CA  1 
ATOM   2485 C C   . GLN B 2 98  ? 130.922 119.326 121.382 1.00 58.10 ? 98  GLN B C   1 
ATOM   2486 O O   . GLN B 2 98  ? 131.348 119.995 122.330 1.00 56.84 ? 98  GLN B O   1 
ATOM   2487 C CB  . GLN B 2 98  ? 132.803 118.151 120.250 1.00 57.04 ? 98  GLN B CB  1 
ATOM   2488 C CG  . GLN B 2 98  ? 133.665 116.914 120.107 1.00 56.52 ? 98  GLN B CG  1 
ATOM   2489 C CD  . GLN B 2 98  ? 134.333 116.827 118.754 1.00 55.97 ? 98  GLN B CD  1 
ATOM   2490 O OE1 . GLN B 2 98  ? 133.726 116.407 117.776 1.00 53.66 ? 98  GLN B OE1 1 
ATOM   2491 N NE2 . GLN B 2 98  ? 135.595 117.234 118.693 1.00 59.30 ? 98  GLN B NE2 1 
ATOM   2492 N N   . CYS B 2 99  ? 129.940 119.758 120.588 1.00 57.87 ? 99  CYS B N   1 
ATOM   2493 C CA  . CYS B 2 99  ? 129.312 121.052 120.825 1.00 52.67 ? 99  CYS B CA  1 
ATOM   2494 C C   . CYS B 2 99  ? 128.581 121.075 122.160 1.00 54.34 ? 99  CYS B C   1 
ATOM   2495 O O   . CYS B 2 99  ? 128.623 122.077 122.883 1.00 55.95 ? 99  CYS B O   1 
ATOM   2496 C CB  . CYS B 2 99  ? 128.350 121.380 119.683 1.00 52.62 ? 99  CYS B CB  1 
ATOM   2497 S SG  . CYS B 2 99  ? 129.052 121.161 118.030 1.00 60.26 ? 99  CYS B SG  1 
ATOM   2498 N N   . PHE B 2 100 ? 127.905 119.978 122.504 1.00 47.89 ? 100 PHE B N   1 
ATOM   2499 C CA  . PHE B 2 100 ? 127.077 119.913 123.708 1.00 41.90 ? 100 PHE B CA  1 
ATOM   2500 C C   . PHE B 2 100 ? 127.938 119.454 124.880 1.00 44.01 ? 100 PHE B C   1 
ATOM   2501 O O   . PHE B 2 100 ? 127.905 118.297 125.304 1.00 53.12 ? 100 PHE B O   1 
ATOM   2502 C CB  . PHE B 2 100 ? 125.893 118.983 123.487 1.00 44.99 ? 100 PHE B CB  1 
ATOM   2503 C CG  . PHE B 2 100 ? 125.047 119.351 122.305 1.00 48.22 ? 100 PHE B CG  1 
ATOM   2504 C CD1 . PHE B 2 100 ? 123.999 120.241 122.437 1.00 51.15 ? 100 PHE B CD1 1 
ATOM   2505 C CD2 . PHE B 2 100 ? 125.294 118.796 121.064 1.00 46.80 ? 100 PHE B CD2 1 
ATOM   2506 C CE1 . PHE B 2 100 ? 123.220 120.575 121.353 1.00 49.95 ? 100 PHE B CE1 1 
ATOM   2507 C CE2 . PHE B 2 100 ? 124.518 119.127 119.977 1.00 43.45 ? 100 PHE B CE2 1 
ATOM   2508 C CZ  . PHE B 2 100 ? 123.481 120.016 120.120 1.00 44.25 ? 100 PHE B CZ  1 
ATOM   2509 N N   . ASN B 2 101 ? 128.730 120.393 125.403 1.00 42.44 ? 101 ASN B N   1 
ATOM   2510 C CA  . ASN B 2 101 ? 129.540 120.167 126.594 1.00 45.08 ? 101 ASN B CA  1 
ATOM   2511 C C   . ASN B 2 101 ? 129.272 121.182 127.695 1.00 48.22 ? 101 ASN B C   1 
ATOM   2512 O O   . ASN B 2 101 ? 129.725 120.970 128.826 1.00 49.38 ? 101 ASN B O   1 
ATOM   2513 C CB  . ASN B 2 101 ? 131.035 120.195 126.251 1.00 45.47 ? 101 ASN B CB  1 
ATOM   2514 C CG  . ASN B 2 101 ? 131.371 121.242 125.221 1.00 53.52 ? 101 ASN B CG  1 
ATOM   2515 O OD1 . ASN B 2 101 ? 130.527 122.057 124.849 1.00 56.27 ? 101 ASN B OD1 1 
ATOM   2516 N ND2 . ASN B 2 101 ? 132.607 121.236 124.759 1.00 51.53 ? 101 ASN B ND2 1 
ATOM   2517 N N   . ASP B 2 102 ? 128.559 122.272 127.401 1.00 45.80 ? 102 ASP B N   1 
ATOM   2518 C CA  . ASP B 2 102 ? 128.171 123.263 128.399 1.00 49.20 ? 102 ASP B CA  1 
ATOM   2519 C C   . ASP B 2 102 ? 126.680 123.229 128.717 1.00 50.30 ? 102 ASP B C   1 
ATOM   2520 O O   . ASP B 2 102 ? 126.199 124.093 129.458 1.00 51.36 ? 102 ASP B O   1 
ATOM   2521 C CB  . ASP B 2 102 ? 128.584 124.669 127.939 1.00 51.27 ? 102 ASP B CB  1 
ATOM   2522 C CG  . ASP B 2 102 ? 128.038 125.034 126.564 1.00 52.86 ? 102 ASP B CG  1 
ATOM   2523 O OD1 . ASP B 2 102 ? 127.068 124.403 126.095 1.00 48.82 ? 102 ASP B OD1 1 
ATOM   2524 O OD2 . ASP B 2 102 ? 128.594 125.966 125.945 1.00 54.25 ? 102 ASP B OD2 1 
ATOM   2525 N N   . VAL B 2 103 ? 125.936 122.260 128.183 1.00 43.53 ? 103 VAL B N   1 
ATOM   2526 C CA  . VAL B 2 103 ? 124.511 122.143 128.473 1.00 41.17 ? 103 VAL B CA  1 
ATOM   2527 C C   . VAL B 2 103 ? 124.344 121.734 129.928 1.00 44.33 ? 103 VAL B C   1 
ATOM   2528 O O   . VAL B 2 103 ? 125.266 121.180 130.538 1.00 41.18 ? 103 VAL B O   1 
ATOM   2529 C CB  . VAL B 2 103 ? 123.817 121.139 127.532 1.00 37.03 ? 103 VAL B CB  1 
ATOM   2530 C CG1 . VAL B 2 103 ? 123.965 121.581 126.090 1.00 41.64 ? 103 VAL B CG1 1 
ATOM   2531 C CG2 . VAL B 2 103 ? 124.354 119.722 127.728 1.00 36.34 ? 103 VAL B CG2 1 
ATOM   2532 N N   . THR B 2 104 ? 123.169 122.009 130.497 1.00 41.57 ? 104 THR B N   1 
ATOM   2533 C CA  . THR B 2 104 ? 122.923 121.669 131.893 1.00 35.34 ? 104 THR B CA  1 
ATOM   2534 C C   . THR B 2 104 ? 122.939 120.161 132.109 1.00 39.84 ? 104 THR B C   1 
ATOM   2535 O O   . THR B 2 104 ? 123.612 119.664 133.018 1.00 36.21 ? 104 THR B O   1 
ATOM   2536 C CB  . THR B 2 104 ? 121.584 122.253 132.347 1.00 30.25 ? 104 THR B CB  1 
ATOM   2537 O OG1 . THR B 2 104 ? 121.488 123.617 131.924 1.00 40.19 ? 104 THR B OG1 1 
ATOM   2538 C CG2 . THR B 2 104 ? 121.455 122.187 133.861 1.00 32.40 ? 104 THR B CG2 1 
ATOM   2539 N N   . ALA B 2 105 ? 122.210 119.418 131.280 1.00 35.80 ? 105 ALA B N   1 
ATOM   2540 C CA  . ALA B 2 105 ? 122.076 117.984 131.478 1.00 29.92 ? 105 ALA B CA  1 
ATOM   2541 C C   . ALA B 2 105 ? 121.581 117.343 130.194 1.00 27.43 ? 105 ALA B C   1 
ATOM   2542 O O   . ALA B 2 105 ? 120.830 117.952 129.430 1.00 40.05 ? 105 ALA B O   1 
ATOM   2543 C CB  . ALA B 2 105 ? 121.111 117.669 132.624 1.00 35.70 ? 105 ALA B CB  1 
ATOM   2544 N N   . ILE B 2 106 ? 122.012 116.109 129.973 1.00 25.11 ? 106 ILE B N   1 
ATOM   2545 C CA  . ILE B 2 106 ? 121.542 115.283 128.870 1.00 25.13 ? 106 ILE B CA  1 
ATOM   2546 C C   . ILE B 2 106 ? 120.355 114.476 129.362 1.00 26.63 ? 106 ILE B C   1 
ATOM   2547 O O   . ILE B 2 106 ? 120.376 113.946 130.479 1.00 48.20 ? 106 ILE B O   1 
ATOM   2548 C CB  . ILE B 2 106 ? 122.662 114.359 128.353 1.00 27.95 ? 106 ILE B CB  1 
ATOM   2549 C CG1 . ILE B 2 106 ? 123.747 115.178 127.652 1.00 30.47 ? 106 ILE B CG1 1 
ATOM   2550 C CG2 . ILE B 2 106 ? 122.093 113.303 127.411 1.00 38.04 ? 106 ILE B CG2 1 
ATOM   2551 C CD1 . ILE B 2 106 ? 125.064 114.455 127.509 1.00 32.89 ? 106 ILE B CD1 1 
ATOM   2552 N N   . ILE B 2 107 ? 119.317 114.382 128.536 1.00 17.06 ? 107 ILE B N   1 
ATOM   2553 C CA  . ILE B 2 107 ? 118.139 113.572 128.827 1.00 21.52 ? 107 ILE B CA  1 
ATOM   2554 C C   . ILE B 2 107 ? 118.225 112.317 127.974 1.00 34.17 ? 107 ILE B C   1 
ATOM   2555 O O   . ILE B 2 107 ? 118.332 112.401 126.746 1.00 50.86 ? 107 ILE B O   1 
ATOM   2556 C CB  . ILE B 2 107 ? 116.833 114.337 128.553 1.00 18.58 ? 107 ILE B CB  1 
ATOM   2557 C CG1 . ILE B 2 107 ? 116.751 115.570 129.461 1.00 27.63 ? 107 ILE B CG1 1 
ATOM   2558 C CG2 . ILE B 2 107 ? 115.632 113.396 128.757 1.00 25.92 ? 107 ILE B CG2 1 
ATOM   2559 C CD1 . ILE B 2 107 ? 115.579 116.482 129.186 1.00 32.36 ? 107 ILE B CD1 1 
ATOM   2560 N N   . PHE B 2 108 ? 118.177 111.159 128.626 1.00 29.37 ? 108 PHE B N   1 
ATOM   2561 C CA  . PHE B 2 108 ? 118.237 109.865 127.964 1.00 28.31 ? 108 PHE B CA  1 
ATOM   2562 C C   . PHE B 2 108 ? 116.907 109.156 128.164 1.00 34.39 ? 108 PHE B C   1 
ATOM   2563 O O   . PHE B 2 108 ? 116.425 109.047 129.296 1.00 46.30 ? 108 PHE B O   1 
ATOM   2564 C CB  . PHE B 2 108 ? 119.382 109.020 128.521 1.00 31.28 ? 108 PHE B CB  1 
ATOM   2565 C CG  . PHE B 2 108 ? 119.961 108.057 127.530 1.00 37.26 ? 108 PHE B CG  1 
ATOM   2566 C CD1 . PHE B 2 108 ? 119.269 106.917 127.165 1.00 35.46 ? 108 PHE B CD1 1 
ATOM   2567 C CD2 . PHE B 2 108 ? 121.199 108.294 126.962 1.00 43.40 ? 108 PHE B CD2 1 
ATOM   2568 C CE1 . PHE B 2 108 ? 119.804 106.031 126.253 1.00 39.50 ? 108 PHE B CE1 1 
ATOM   2569 C CE2 . PHE B 2 108 ? 121.736 107.412 126.049 1.00 44.68 ? 108 PHE B CE2 1 
ATOM   2570 C CZ  . PHE B 2 108 ? 121.038 106.279 125.694 1.00 43.37 ? 108 PHE B CZ  1 
ATOM   2571 N N   . VAL B 2 109 ? 116.320 108.683 127.068 1.00 31.52 ? 109 VAL B N   1 
ATOM   2572 C CA  . VAL B 2 109 ? 115.036 107.994 127.082 1.00 29.59 ? 109 VAL B CA  1 
ATOM   2573 C C   . VAL B 2 109 ? 115.225 106.628 126.441 1.00 37.20 ? 109 VAL B C   1 
ATOM   2574 O O   . VAL B 2 109 ? 115.791 106.525 125.348 1.00 46.01 ? 109 VAL B O   1 
ATOM   2575 C CB  . VAL B 2 109 ? 113.951 108.792 126.336 1.00 28.24 ? 109 VAL B CB  1 
ATOM   2576 C CG1 . VAL B 2 109 ? 112.567 108.271 126.688 1.00 34.16 ? 109 VAL B CG1 1 
ATOM   2577 C CG2 . VAL B 2 109 ? 114.067 110.268 126.662 1.00 32.96 ? 109 VAL B CG2 1 
ATOM   2578 N N   . VAL B 2 110 ? 114.754 105.585 127.124 1.00 34.34 ? 110 VAL B N   1 
ATOM   2579 C CA  . VAL B 2 110 ? 114.796 104.220 126.621 1.00 38.84 ? 110 VAL B CA  1 
ATOM   2580 C C   . VAL B 2 110 ? 113.430 103.588 126.840 1.00 39.10 ? 110 VAL B C   1 
ATOM   2581 O O   . VAL B 2 110 ? 112.680 103.968 127.739 1.00 44.06 ? 110 VAL B O   1 
ATOM   2582 C CB  . VAL B 2 110 ? 115.898 103.381 127.298 1.00 41.07 ? 110 VAL B CB  1 
ATOM   2583 C CG1 . VAL B 2 110 ? 117.217 104.125 127.271 1.00 40.47 ? 110 VAL B CG1 1 
ATOM   2584 C CG2 . VAL B 2 110 ? 115.510 103.035 128.724 1.00 40.05 ? 110 VAL B CG2 1 
ATOM   2585 N N   . ASP B 2 111 ? 113.119 102.600 126.005 1.00 37.10 ? 111 ASP B N   1 
ATOM   2586 C CA  . ASP B 2 111 ? 111.867 101.855 126.081 1.00 44.51 ? 111 ASP B CA  1 
ATOM   2587 C C   . ASP B 2 111 ? 112.174 100.488 126.675 1.00 54.08 ? 111 ASP B C   1 
ATOM   2588 O O   . ASP B 2 111 ? 112.786 99.642  126.014 1.00 57.20 ? 111 ASP B O   1 
ATOM   2589 C CB  . ASP B 2 111 ? 111.220 101.723 124.704 1.00 47.90 ? 111 ASP B CB  1 
ATOM   2590 N N   . SER B 2 112 ? 111.752 100.274 127.918 1.00 58.12 ? 112 SER B N   1 
ATOM   2591 C CA  . SER B 2 112 ? 111.925 98.990  128.579 1.00 53.38 ? 112 SER B CA  1 
ATOM   2592 C C   . SER B 2 112 ? 110.911 97.949  128.125 1.00 53.86 ? 112 SER B C   1 
ATOM   2593 O O   . SER B 2 112 ? 111.014 96.789  128.535 1.00 59.25 ? 112 SER B O   1 
ATOM   2594 C CB  . SER B 2 112 ? 111.826 99.164  130.096 1.00 48.74 ? 112 SER B CB  1 
ATOM   2595 O OG  . SER B 2 112 ? 110.677 99.914  130.442 1.00 56.96 ? 112 SER B OG  1 
ATOM   2596 N N   . SER B 2 113 ? 109.933 98.332  127.301 1.00 59.32 ? 113 SER B N   1 
ATOM   2597 C CA  . SER B 2 113 ? 108.965 97.364  126.800 1.00 63.49 ? 113 SER B CA  1 
ATOM   2598 C C   . SER B 2 113 ? 109.634 96.318  125.917 1.00 65.06 ? 113 SER B C   1 
ATOM   2599 O O   . SER B 2 113 ? 109.338 95.123  126.028 1.00 66.88 ? 113 SER B O   1 
ATOM   2600 C CB  . SER B 2 113 ? 107.863 98.086  126.029 1.00 65.29 ? 113 SER B CB  1 
ATOM   2601 O OG  . SER B 2 113 ? 107.046 98.839  126.905 1.00 64.91 ? 113 SER B OG  1 
ATOM   2602 N N   . ASP B 2 114 ? 110.536 96.747  125.038 1.00 70.39 ? 114 ASP B N   1 
ATOM   2603 C CA  . ASP B 2 114 ? 111.208 95.850  124.105 1.00 75.96 ? 114 ASP B CA  1 
ATOM   2604 C C   . ASP B 2 114 ? 112.497 95.337  124.735 1.00 76.94 ? 114 ASP B C   1 
ATOM   2605 O O   . ASP B 2 114 ? 113.443 96.105  124.940 1.00 72.91 ? 114 ASP B O   1 
ATOM   2606 C CB  . ASP B 2 114 ? 111.500 96.567  122.788 1.00 75.29 ? 114 ASP B CB  1 
ATOM   2607 C CG  . ASP B 2 114 ? 110.239 96.900  122.014 1.00 76.11 ? 114 ASP B CG  1 
ATOM   2608 O OD1 . ASP B 2 114 ? 109.332 96.043  121.954 1.00 74.85 ? 114 ASP B OD1 1 
ATOM   2609 O OD2 . ASP B 2 114 ? 110.155 98.018  121.464 1.00 75.09 ? 114 ASP B OD2 1 
ATOM   2610 N N   . TYR B 2 115 ? 112.531 94.041  125.037 1.00 77.80 ? 115 TYR B N   1 
ATOM   2611 C CA  . TYR B 2 115 ? 113.698 93.411  125.636 1.00 75.17 ? 115 TYR B CA  1 
ATOM   2612 C C   . TYR B 2 115 ? 114.748 92.997  124.614 1.00 75.86 ? 115 TYR B C   1 
ATOM   2613 O O   . TYR B 2 115 ? 115.905 92.786  124.991 1.00 73.22 ? 115 TYR B O   1 
ATOM   2614 C CB  . TYR B 2 115 ? 113.274 92.175  126.431 1.00 73.39 ? 115 TYR B CB  1 
ATOM   2615 C CG  . TYR B 2 115 ? 112.391 92.474  127.618 1.00 71.93 ? 115 TYR B CG  1 
ATOM   2616 C CD1 . TYR B 2 115 ? 112.928 92.931  128.811 1.00 72.02 ? 115 TYR B CD1 1 
ATOM   2617 C CD2 . TYR B 2 115 ? 111.017 92.298  127.543 1.00 71.20 ? 115 TYR B CD2 1 
ATOM   2618 C CE1 . TYR B 2 115 ? 112.123 93.201  129.898 1.00 72.19 ? 115 TYR B CE1 1 
ATOM   2619 C CE2 . TYR B 2 115 ? 110.204 92.566  128.622 1.00 73.45 ? 115 TYR B CE2 1 
ATOM   2620 C CZ  . TYR B 2 115 ? 110.762 93.017  129.797 1.00 74.36 ? 115 TYR B CZ  1 
ATOM   2621 O OH  . TYR B 2 115 ? 109.953 93.286  130.875 1.00 74.47 ? 115 TYR B OH  1 
ATOM   2622 N N   . ASN B 2 116 ? 114.378 92.875  123.337 1.00 80.52 ? 116 ASN B N   1 
ATOM   2623 C CA  . ASN B 2 116 ? 115.321 92.402  122.331 1.00 81.49 ? 116 ASN B CA  1 
ATOM   2624 C C   . ASN B 2 116 ? 116.461 93.384  122.102 1.00 80.31 ? 116 ASN B C   1 
ATOM   2625 O O   . ASN B 2 116 ? 117.568 92.961  121.751 1.00 78.01 ? 116 ASN B O   1 
ATOM   2626 C CB  . ASN B 2 116 ? 114.596 92.140  121.011 1.00 80.28 ? 116 ASN B CB  1 
ATOM   2627 C CG  . ASN B 2 116 ? 113.519 91.079  121.135 1.00 80.06 ? 116 ASN B CG  1 
ATOM   2628 O OD1 . ASN B 2 116 ? 113.745 90.011  121.704 1.00 78.51 ? 116 ASN B OD1 1 
ATOM   2629 N ND2 . ASN B 2 116 ? 112.341 91.369  120.596 1.00 80.64 ? 116 ASN B ND2 1 
ATOM   2630 N N   . ARG B 2 117 ? 116.218 94.684  122.301 1.00 74.74 ? 117 ARG B N   1 
ATOM   2631 C CA  . ARG B 2 117 ? 117.201 95.731  122.041 1.00 73.53 ? 117 ARG B CA  1 
ATOM   2632 C C   . ARG B 2 117 ? 117.538 96.516  123.306 1.00 70.57 ? 117 ARG B C   1 
ATOM   2633 O O   . ARG B 2 117 ? 117.910 97.689  123.233 1.00 69.48 ? 117 ARG B O   1 
ATOM   2634 C CB  . ARG B 2 117 ? 116.709 96.682  120.950 1.00 71.90 ? 117 ARG B CB  1 
ATOM   2635 C CG  . ARG B 2 117 ? 115.412 97.409  121.270 1.00 70.92 ? 117 ARG B CG  1 
ATOM   2636 C CD  . ARG B 2 117 ? 114.742 97.911  120.006 1.00 71.86 ? 117 ARG B CD  1 
ATOM   2637 N NE  . ARG B 2 117 ? 113.819 96.923  119.458 1.00 73.16 ? 117 ARG B NE  1 
ATOM   2638 C CZ  . ARG B 2 117 ? 113.423 96.865  118.192 1.00 73.66 ? 117 ARG B CZ  1 
ATOM   2639 N NH1 . ARG B 2 117 ? 113.827 97.749  117.292 1.00 71.76 ? 117 ARG B NH1 1 
ATOM   2640 N NH2 . ARG B 2 117 ? 112.593 95.895  117.819 1.00 72.24 ? 117 ARG B NH2 1 
ATOM   2641 N N   . LEU B 2 118 ? 117.417 95.886  124.476 1.00 64.82 ? 118 LEU B N   1 
ATOM   2642 C CA  . LEU B 2 118 ? 117.875 96.536  125.700 1.00 64.92 ? 118 LEU B CA  1 
ATOM   2643 C C   . LEU B 2 118 ? 119.391 96.660  125.733 1.00 61.94 ? 118 LEU B C   1 
ATOM   2644 O O   . LEU B 2 118 ? 119.922 97.670  126.207 1.00 61.85 ? 118 LEU B O   1 
ATOM   2645 C CB  . LEU B 2 118 ? 117.400 95.771  126.935 1.00 66.76 ? 118 LEU B CB  1 
ATOM   2646 C CG  . LEU B 2 118 ? 116.029 96.124  127.510 1.00 65.65 ? 118 LEU B CG  1 
ATOM   2647 C CD1 . LEU B 2 118 ? 115.591 95.066  128.507 1.00 65.91 ? 118 LEU B CD1 1 
ATOM   2648 C CD2 . LEU B 2 118 ? 116.056 97.491  128.168 1.00 63.03 ? 118 LEU B CD2 1 
ATOM   2649 N N   . GLN B 2 119 ? 120.102 95.639  125.249 1.00 55.43 ? 119 GLN B N   1 
ATOM   2650 C CA  . GLN B 2 119 ? 121.559 95.673  125.302 1.00 56.67 ? 119 GLN B CA  1 
ATOM   2651 C C   . GLN B 2 119 ? 122.110 96.803  124.444 1.00 57.71 ? 119 GLN B C   1 
ATOM   2652 O O   . GLN B 2 119 ? 123.133 97.405  124.785 1.00 55.85 ? 119 GLN B O   1 
ATOM   2653 C CB  . GLN B 2 119 ? 122.141 94.326  124.855 1.00 59.54 ? 119 GLN B CB  1 
ATOM   2654 C CG  . GLN B 2 119 ? 122.520 93.346  125.979 1.00 61.22 ? 119 GLN B CG  1 
ATOM   2655 C CD  . GLN B 2 119 ? 123.510 93.915  126.986 1.00 60.25 ? 119 GLN B CD  1 
ATOM   2656 O OE1 . GLN B 2 119 ? 124.084 94.984  126.776 1.00 54.13 ? 119 GLN B OE1 1 
ATOM   2657 N NE2 . GLN B 2 119 ? 123.709 93.202  128.088 1.00 60.65 ? 119 GLN B NE2 1 
ATOM   2658 N N   . GLU B 2 120 ? 121.443 97.109  123.330 1.00 58.10 ? 120 GLU B N   1 
ATOM   2659 C CA  . GLU B 2 120 ? 121.874 98.230  122.501 1.00 57.94 ? 120 GLU B CA  1 
ATOM   2660 C C   . GLU B 2 120 ? 121.779 99.547  123.261 1.00 59.06 ? 120 GLU B C   1 
ATOM   2661 O O   . GLU B 2 120 ? 122.707 100.364 123.222 1.00 55.36 ? 120 GLU B O   1 
ATOM   2662 C CB  . GLU B 2 120 ? 121.033 98.289  121.226 1.00 55.20 ? 120 GLU B CB  1 
ATOM   2663 N N   . ALA B 2 121 ? 120.670 99.767  123.972 1.00 56.70 ? 121 ALA B N   1 
ATOM   2664 C CA  . ALA B 2 121 ? 120.520 101.001 124.736 1.00 51.90 ? 121 ALA B CA  1 
ATOM   2665 C C   . ALA B 2 121 ? 121.506 101.048 125.895 1.00 51.15 ? 121 ALA B C   1 
ATOM   2666 O O   . ALA B 2 121 ? 122.023 102.117 126.239 1.00 50.14 ? 121 ALA B O   1 
ATOM   2667 C CB  . ALA B 2 121 ? 119.083 101.138 125.238 1.00 45.25 ? 121 ALA B CB  1 
ATOM   2668 N N   . LEU B 2 122 ? 121.776 99.899  126.515 1.00 51.55 ? 122 LEU B N   1 
ATOM   2669 C CA  . LEU B 2 122 ? 122.766 99.859  127.588 1.00 50.69 ? 122 LEU B CA  1 
ATOM   2670 C C   . LEU B 2 122 ? 124.156 100.206 127.063 1.00 52.62 ? 122 LEU B C   1 
ATOM   2671 O O   . LEU B 2 122 ? 124.905 100.951 127.705 1.00 50.32 ? 122 LEU B O   1 
ATOM   2672 C CB  . LEU B 2 122 ? 122.768 98.479  128.252 1.00 53.42 ? 122 LEU B CB  1 
ATOM   2673 C CG  . LEU B 2 122 ? 121.830 98.177  129.433 1.00 50.83 ? 122 LEU B CG  1 
ATOM   2674 C CD1 . LEU B 2 122 ? 122.385 98.801  130.677 1.00 53.04 ? 122 LEU B CD1 1 
ATOM   2675 C CD2 . LEU B 2 122 ? 120.376 98.612  129.223 1.00 50.19 ? 122 LEU B CD2 1 
ATOM   2676 N N   . ASN B 2 123 ? 124.520 99.678  125.892 1.00 56.53 ? 123 ASN B N   1 
ATOM   2677 C CA  . ASN B 2 123 ? 125.807 100.022 125.293 1.00 54.51 ? 123 ASN B CA  1 
ATOM   2678 C C   . ASN B 2 123 ? 125.857 101.497 124.916 1.00 51.65 ? 123 ASN B C   1 
ATOM   2679 O O   . ASN B 2 123 ? 126.904 102.144 125.042 1.00 49.98 ? 123 ASN B O   1 
ATOM   2680 C CB  . ASN B 2 123 ? 126.070 99.146  124.067 1.00 55.64 ? 123 ASN B CB  1 
ATOM   2681 C CG  . ASN B 2 123 ? 126.318 97.691  124.425 1.00 56.50 ? 123 ASN B CG  1 
ATOM   2682 O OD1 . ASN B 2 123 ? 125.611 96.798  123.962 1.00 53.97 ? 123 ASN B OD1 1 
ATOM   2683 N ND2 . ASN B 2 123 ? 127.337 97.446  125.242 1.00 55.96 ? 123 ASN B ND2 1 
ATOM   2684 N N   . ASP B 2 124 ? 124.738 102.044 124.440 1.00 47.61 ? 124 ASP B N   1 
ATOM   2685 C CA  . ASP B 2 124 ? 124.693 103.465 124.116 1.00 46.57 ? 124 ASP B CA  1 
ATOM   2686 C C   . ASP B 2 124 ? 124.903 104.304 125.372 1.00 47.12 ? 124 ASP B C   1 
ATOM   2687 O O   . ASP B 2 124 ? 125.614 105.318 125.352 1.00 49.14 ? 124 ASP B O   1 
ATOM   2688 C CB  . ASP B 2 124 ? 123.362 103.803 123.444 1.00 49.25 ? 124 ASP B CB  1 
ATOM   2689 C CG  . ASP B 2 124 ? 123.282 105.248 122.998 1.00 50.46 ? 124 ASP B CG  1 
ATOM   2690 O OD1 . ASP B 2 124 ? 124.324 105.935 122.991 1.00 50.97 ? 124 ASP B OD1 1 
ATOM   2691 O OD2 . ASP B 2 124 ? 122.176 105.696 122.632 1.00 50.12 ? 124 ASP B OD2 1 
ATOM   2692 N N   . PHE B 2 125 ? 124.286 103.888 126.481 1.00 41.21 ? 125 PHE B N   1 
ATOM   2693 C CA  . PHE B 2 125 ? 124.509 104.572 127.750 1.00 48.21 ? 125 PHE B CA  1 
ATOM   2694 C C   . PHE B 2 125 ? 125.962 104.455 128.187 1.00 48.06 ? 125 PHE B C   1 
ATOM   2695 O O   . PHE B 2 125 ? 126.529 105.415 128.713 1.00 46.01 ? 125 PHE B O   1 
ATOM   2696 C CB  . PHE B 2 125 ? 123.579 104.016 128.828 1.00 45.30 ? 125 PHE B CB  1 
ATOM   2697 C CG  . PHE B 2 125 ? 123.435 104.918 130.022 1.00 39.95 ? 125 PHE B CG  1 
ATOM   2698 C CD1 . PHE B 2 125 ? 124.387 104.923 131.026 1.00 35.86 ? 125 PHE B CD1 1 
ATOM   2699 C CD2 . PHE B 2 125 ? 122.355 105.775 130.131 1.00 45.73 ? 125 PHE B CD2 1 
ATOM   2700 C CE1 . PHE B 2 125 ? 124.260 105.755 132.117 1.00 41.71 ? 125 PHE B CE1 1 
ATOM   2701 C CE2 . PHE B 2 125 ? 122.224 106.611 131.223 1.00 45.55 ? 125 PHE B CE2 1 
ATOM   2702 C CZ  . PHE B 2 125 ? 123.177 106.600 132.215 1.00 41.16 ? 125 PHE B CZ  1 
ATOM   2703 N N   . LYS B 2 126 ? 126.577 103.284 127.995 1.00 53.49 ? 126 LYS B N   1 
ATOM   2704 C CA  . LYS B 2 126 ? 128.004 103.150 128.284 1.00 51.75 ? 126 LYS B CA  1 
ATOM   2705 C C   . LYS B 2 126 ? 128.818 104.156 127.483 1.00 51.48 ? 126 LYS B C   1 
ATOM   2706 O O   . LYS B 2 126 ? 129.687 104.846 128.032 1.00 52.47 ? 126 LYS B O   1 
ATOM   2707 C CB  . LYS B 2 126 ? 128.495 101.732 127.972 1.00 55.69 ? 126 LYS B CB  1 
ATOM   2708 C CG  . LYS B 2 126 ? 127.913 100.621 128.837 1.00 55.66 ? 126 LYS B CG  1 
ATOM   2709 C CD  . LYS B 2 126 ? 128.846 100.251 129.998 1.00 53.59 ? 126 LYS B CD  1 
ATOM   2710 C CE  . LYS B 2 126 ? 130.073 99.445  129.573 1.00 54.63 ? 126 LYS B CE  1 
ATOM   2711 N NZ  . LYS B 2 126 ? 131.121 99.493  130.631 1.00 50.75 ? 126 LYS B NZ  1 
ATOM   2712 N N   . SER B 2 127 ? 128.531 104.263 126.185 1.00 49.24 ? 127 SER B N   1 
ATOM   2713 C CA  . SER B 2 127 ? 129.308 105.144 125.322 1.00 48.20 ? 127 SER B CA  1 
ATOM   2714 C C   . SER B 2 127 ? 129.143 106.601 125.729 1.00 50.51 ? 127 SER B C   1 
ATOM   2715 O O   . SER B 2 127 ? 130.113 107.368 125.717 1.00 51.20 ? 127 SER B O   1 
ATOM   2716 C CB  . SER B 2 127 ? 128.894 104.953 123.864 1.00 46.94 ? 127 SER B CB  1 
ATOM   2717 O OG  . SER B 2 127 ? 127.486 104.981 123.732 1.00 47.78 ? 127 SER B OG  1 
ATOM   2718 N N   . ILE B 2 128 ? 127.923 107.005 126.089 1.00 47.17 ? 128 ILE B N   1 
ATOM   2719 C CA  . ILE B 2 128 ? 127.704 108.407 126.436 1.00 48.49 ? 128 ILE B CA  1 
ATOM   2720 C C   . ILE B 2 128 ? 128.247 108.712 127.830 1.00 41.80 ? 128 ILE B C   1 
ATOM   2721 O O   . ILE B 2 128 ? 128.698 109.831 128.099 1.00 44.44 ? 128 ILE B O   1 
ATOM   2722 C CB  . ILE B 2 128 ? 126.212 108.775 126.292 1.00 47.66 ? 128 ILE B CB  1 
ATOM   2723 C CG1 . ILE B 2 128 ? 126.077 110.258 125.939 1.00 46.77 ? 128 ILE B CG1 1 
ATOM   2724 C CG2 . ILE B 2 128 ? 125.415 108.450 127.554 1.00 44.97 ? 128 ILE B CG2 1 
ATOM   2725 C CD1 . ILE B 2 128 ? 124.668 110.696 125.686 1.00 44.57 ? 128 ILE B CD1 1 
ATOM   2726 N N   . TRP B 2 129 ? 128.217 107.732 128.737 1.00 37.27 ? 129 TRP B N   1 
ATOM   2727 C CA  . TRP B 2 129 ? 128.784 107.937 130.066 1.00 41.58 ? 129 TRP B CA  1 
ATOM   2728 C C   . TRP B 2 129 ? 130.295 108.093 129.988 1.00 48.62 ? 129 TRP B C   1 
ATOM   2729 O O   . TRP B 2 129 ? 130.867 109.004 130.597 1.00 45.71 ? 129 TRP B O   1 
ATOM   2730 C CB  . TRP B 2 129 ? 128.438 106.753 130.973 1.00 43.83 ? 129 TRP B CB  1 
ATOM   2731 C CG  . TRP B 2 129 ? 128.305 107.022 132.458 1.00 42.08 ? 129 TRP B CG  1 
ATOM   2732 C CD1 . TRP B 2 129 ? 128.768 106.222 133.462 1.00 46.01 ? 129 TRP B CD1 1 
ATOM   2733 C CD2 . TRP B 2 129 ? 127.574 108.081 133.104 1.00 43.22 ? 129 TRP B CD2 1 
ATOM   2734 N NE1 . TRP B 2 129 ? 128.431 106.744 134.683 1.00 49.55 ? 129 TRP B NE1 1 
ATOM   2735 C CE2 . TRP B 2 129 ? 127.691 107.880 134.493 1.00 46.82 ? 129 TRP B CE2 1 
ATOM   2736 C CE3 . TRP B 2 129 ? 126.852 109.187 132.645 1.00 43.86 ? 129 TRP B CE3 1 
ATOM   2737 C CZ2 . TRP B 2 129 ? 127.121 108.743 135.423 1.00 44.92 ? 129 TRP B CZ2 1 
ATOM   2738 C CZ3 . TRP B 2 129 ? 126.292 110.045 133.573 1.00 42.09 ? 129 TRP B CZ3 1 
ATOM   2739 C CH2 . TRP B 2 129 ? 126.424 109.814 134.944 1.00 41.53 ? 129 TRP B CH2 1 
ATOM   2740 N N   . ASN B 2 130 ? 130.960 107.210 129.237 1.00 61.73 ? 130 ASN B N   1 
ATOM   2741 C CA  . ASN B 2 130 ? 132.416 107.176 129.170 1.00 58.30 ? 130 ASN B CA  1 
ATOM   2742 C C   . ASN B 2 130 ? 132.982 108.088 128.087 1.00 58.40 ? 130 ASN B C   1 
ATOM   2743 O O   . ASN B 2 130 ? 134.129 107.898 127.664 1.00 59.45 ? 130 ASN B O   1 
ATOM   2744 C CB  . ASN B 2 130 ? 132.893 105.740 128.950 1.00 55.32 ? 130 ASN B CB  1 
ATOM   2745 C CG  . ASN B 2 130 ? 132.200 104.750 129.861 1.00 56.24 ? 130 ASN B CG  1 
ATOM   2746 O OD1 . ASN B 2 130 ? 132.020 105.005 131.052 1.00 54.62 ? 130 ASN B OD1 1 
ATOM   2747 N ND2 . ASN B 2 130 ? 131.811 103.606 129.308 1.00 53.90 ? 130 ASN B ND2 1 
ATOM   2748 N N   . ASN B 2 131 ? 132.215 109.069 127.621 1.00 53.92 ? 131 ASN B N   1 
ATOM   2749 C CA  . ASN B 2 131 ? 132.731 109.999 126.634 1.00 49.70 ? 131 ASN B CA  1 
ATOM   2750 C C   . ASN B 2 131 ? 133.807 110.881 127.259 1.00 54.20 ? 131 ASN B C   1 
ATOM   2751 O O   . ASN B 2 131 ? 133.842 111.102 128.473 1.00 54.53 ? 131 ASN B O   1 
ATOM   2752 C CB  . ASN B 2 131 ? 131.605 110.857 126.062 1.00 51.90 ? 131 ASN B CB  1 
ATOM   2753 C CG  . ASN B 2 131 ? 131.964 111.466 124.723 1.00 54.57 ? 131 ASN B CG  1 
ATOM   2754 O OD1 . ASN B 2 131 ? 132.920 112.232 124.615 1.00 51.52 ? 131 ASN B OD1 1 
ATOM   2755 N ND2 . ASN B 2 131 ? 131.200 111.123 123.693 1.00 52.55 ? 131 ASN B ND2 1 
ATOM   2756 N N   . ARG B 2 132 ? 134.698 111.388 126.409 1.00 58.30 ? 132 ARG B N   1 
ATOM   2757 C CA  . ARG B 2 132 ? 135.813 112.202 126.876 1.00 57.93 ? 132 ARG B CA  1 
ATOM   2758 C C   . ARG B 2 132 ? 135.443 113.674 127.019 1.00 57.13 ? 132 ARG B C   1 
ATOM   2759 O O   . ARG B 2 132 ? 136.028 114.378 127.849 1.00 58.64 ? 132 ARG B O   1 
ATOM   2760 C CB  . ARG B 2 132 ? 137.016 112.020 125.938 1.00 58.82 ? 132 ARG B CB  1 
ATOM   2761 C CG  . ARG B 2 132 ? 136.921 112.655 124.530 1.00 56.12 ? 132 ARG B CG  1 
ATOM   2762 C CD  . ARG B 2 132 ? 138.290 113.047 123.976 1.00 57.85 ? 132 ARG B CD  1 
ATOM   2763 N NE  . ARG B 2 132 ? 138.982 114.026 124.813 1.00 64.15 ? 132 ARG B NE  1 
ATOM   2764 C CZ  . ARG B 2 132 ? 140.300 114.159 124.917 1.00 61.68 ? 132 ARG B CZ  1 
ATOM   2765 N NH1 . ARG B 2 132 ? 141.139 113.403 124.224 1.00 57.20 ? 132 ARG B NH1 1 
ATOM   2766 N NH2 . ARG B 2 132 ? 140.793 115.085 125.735 1.00 61.28 ? 132 ARG B NH2 1 
ATOM   2767 N N   . TRP B 2 133 ? 134.485 114.152 126.229 1.00 52.51 ? 133 TRP B N   1 
ATOM   2768 C CA  . TRP B 2 133 ? 134.017 115.528 126.306 1.00 55.52 ? 133 TRP B CA  1 
ATOM   2769 C C   . TRP B 2 133 ? 132.848 115.714 127.265 1.00 56.59 ? 133 TRP B C   1 
ATOM   2770 O O   . TRP B 2 133 ? 132.446 116.857 127.503 1.00 55.28 ? 133 TRP B O   1 
ATOM   2771 C CB  . TRP B 2 133 ? 133.615 116.017 124.912 1.00 57.18 ? 133 TRP B CB  1 
ATOM   2772 C CG  . TRP B 2 133 ? 134.710 115.870 123.916 1.00 57.62 ? 133 TRP B CG  1 
ATOM   2773 C CD1 . TRP B 2 133 ? 134.716 115.069 122.815 1.00 57.50 ? 133 TRP B CD1 1 
ATOM   2774 C CD2 . TRP B 2 133 ? 135.973 116.541 123.934 1.00 56.32 ? 133 TRP B CD2 1 
ATOM   2775 N NE1 . TRP B 2 133 ? 135.906 115.202 122.141 1.00 55.59 ? 133 TRP B NE1 1 
ATOM   2776 C CE2 . TRP B 2 133 ? 136.696 116.100 122.810 1.00 53.74 ? 133 TRP B CE2 1 
ATOM   2777 C CE3 . TRP B 2 133 ? 136.563 117.472 124.793 1.00 55.15 ? 133 TRP B CE3 1 
ATOM   2778 C CZ2 . TRP B 2 133 ? 137.978 116.559 122.521 1.00 51.83 ? 133 TRP B CZ2 1 
ATOM   2779 C CZ3 . TRP B 2 133 ? 137.834 117.926 124.506 1.00 51.96 ? 133 TRP B CZ3 1 
ATOM   2780 C CH2 . TRP B 2 133 ? 138.529 117.470 123.380 1.00 51.92 ? 133 TRP B CH2 1 
ATOM   2781 N N   . LEU B 2 134 ? 132.301 114.632 127.821 1.00 55.70 ? 134 LEU B N   1 
ATOM   2782 C CA  . LEU B 2 134 ? 131.155 114.673 128.721 1.00 52.97 ? 134 LEU B CA  1 
ATOM   2783 C C   . LEU B 2 134 ? 131.524 114.137 130.101 1.00 54.49 ? 134 LEU B C   1 
ATOM   2784 O O   . LEU B 2 134 ? 130.754 113.409 130.729 1.00 49.38 ? 134 LEU B O   1 
ATOM   2785 C CB  . LEU B 2 134 ? 129.986 113.885 128.137 1.00 49.02 ? 134 LEU B CB  1 
ATOM   2786 C CG  . LEU B 2 134 ? 129.598 114.202 126.688 1.00 45.98 ? 134 LEU B CG  1 
ATOM   2787 C CD1 . LEU B 2 134 ? 128.393 113.382 126.269 1.00 48.70 ? 134 LEU B CD1 1 
ATOM   2788 C CD2 . LEU B 2 134 ? 129.308 115.682 126.505 1.00 44.04 ? 134 LEU B CD2 1 
ATOM   2789 N N   . ARG B 2 135 ? 132.709 114.501 130.588 1.00 58.47 ? 135 ARG B N   1 
ATOM   2790 C CA  . ARG B 2 135 ? 133.156 114.144 131.929 1.00 56.91 ? 135 ARG B CA  1 
ATOM   2791 C C   . ARG B 2 135 ? 132.641 115.095 133.004 1.00 58.30 ? 135 ARG B C   1 
ATOM   2792 O O   . ARG B 2 135 ? 132.974 114.909 134.178 1.00 59.41 ? 135 ARG B O   1 
ATOM   2793 C CB  . ARG B 2 135 ? 134.694 114.101 131.983 1.00 57.24 ? 135 ARG B CB  1 
ATOM   2794 C CG  . ARG B 2 135 ? 135.327 112.774 131.574 1.00 60.19 ? 135 ARG B CG  1 
ATOM   2795 C CD  . ARG B 2 135 ? 136.650 112.539 132.331 1.00 57.89 ? 135 ARG B CD  1 
ATOM   2796 N NE  . ARG B 2 135 ? 137.314 111.288 131.980 1.00 58.90 ? 135 ARG B NE  1 
ATOM   2797 C CZ  . ARG B 2 135 ? 137.751 110.959 130.771 1.00 62.94 ? 135 ARG B CZ  1 
ATOM   2798 N NH1 . ARG B 2 135 ? 137.766 111.829 129.775 1.00 62.77 ? 135 ARG B NH1 1 
ATOM   2799 N NH2 . ARG B 2 135 ? 138.210 109.729 130.563 1.00 61.60 ? 135 ARG B NH2 1 
ATOM   2800 N N   . THR B 2 136 ? 131.849 116.108 132.635 1.00 54.30 ? 136 THR B N   1 
ATOM   2801 C CA  . THR B 2 136 ? 131.281 117.054 133.586 1.00 50.81 ? 136 THR B CA  1 
ATOM   2802 C C   . THR B 2 136 ? 129.775 117.232 133.455 1.00 49.36 ? 136 THR B C   1 
ATOM   2803 O O   . THR B 2 136 ? 129.201 118.007 134.229 1.00 52.74 ? 136 THR B O   1 
ATOM   2804 C CB  . THR B 2 136 ? 131.944 118.434 133.438 1.00 51.83 ? 136 THR B CB  1 
ATOM   2805 O OG1 . THR B 2 136 ? 131.239 119.204 132.457 1.00 54.18 ? 136 THR B OG1 1 
ATOM   2806 C CG2 . THR B 2 136 ? 133.407 118.305 133.028 1.00 52.62 ? 136 THR B CG2 1 
ATOM   2807 N N   . ILE B 2 137 ? 129.120 116.548 132.519 1.00 40.54 ? 137 ILE B N   1 
ATOM   2808 C CA  . ILE B 2 137 ? 127.677 116.661 132.330 1.00 37.11 ? 137 ILE B CA  1 
ATOM   2809 C C   . ILE B 2 137 ? 127.012 115.485 133.032 1.00 37.65 ? 137 ILE B C   1 
ATOM   2810 O O   . ILE B 2 137 ? 127.426 114.334 132.861 1.00 45.31 ? 137 ILE B O   1 
ATOM   2811 C CB  . ILE B 2 137 ? 127.311 116.705 130.837 1.00 38.10 ? 137 ILE B CB  1 
ATOM   2812 C CG1 . ILE B 2 137 ? 127.382 118.149 130.345 1.00 39.86 ? 137 ILE B CG1 1 
ATOM   2813 C CG2 . ILE B 2 137 ? 125.889 116.154 130.576 1.00 43.26 ? 137 ILE B CG2 1 
ATOM   2814 C CD1 . ILE B 2 137 ? 127.501 118.303 128.848 1.00 41.26 ? 137 ILE B CD1 1 
ATOM   2815 N N   . SER B 2 138 ? 125.984 115.780 133.820 1.00 31.61 ? 138 SER B N   1 
ATOM   2816 C CA  . SER B 2 138 ? 125.152 114.753 134.418 1.00 34.34 ? 138 SER B CA  1 
ATOM   2817 C C   . SER B 2 138 ? 123.994 114.417 133.485 1.00 25.12 ? 138 SER B C   1 
ATOM   2818 O O   . SER B 2 138 ? 123.544 115.246 132.691 1.00 40.94 ? 138 SER B O   1 
ATOM   2819 C CB  . SER B 2 138 ? 124.623 115.216 135.773 1.00 42.20 ? 138 SER B CB  1 
ATOM   2820 O OG  . SER B 2 138 ? 123.398 115.905 135.627 1.00 41.29 ? 138 SER B OG  1 
ATOM   2821 N N   . VAL B 2 139 ? 123.511 113.182 133.593 1.00 22.59 ? 139 VAL B N   1 
ATOM   2822 C CA  . VAL B 2 139 ? 122.501 112.635 132.696 1.00 27.67 ? 139 VAL B CA  1 
ATOM   2823 C C   . VAL B 2 139 ? 121.222 112.399 133.482 1.00 27.80 ? 139 VAL B C   1 
ATOM   2824 O O   . VAL B 2 139 ? 121.262 111.934 134.624 1.00 42.12 ? 139 VAL B O   1 
ATOM   2825 C CB  . VAL B 2 139 ? 122.982 111.325 132.037 1.00 37.24 ? 139 VAL B CB  1 
ATOM   2826 C CG1 . VAL B 2 139 ? 121.866 110.699 131.216 1.00 31.81 ? 139 VAL B CG1 1 
ATOM   2827 C CG2 . VAL B 2 139 ? 124.207 111.581 131.168 1.00 37.58 ? 139 VAL B CG2 1 
ATOM   2828 N N   . ILE B 2 140 ? 120.090 112.729 132.867 1.00 25.94 ? 140 ILE B N   1 
ATOM   2829 C CA  . ILE B 2 140 ? 118.769 112.454 133.420 1.00 26.48 ? 140 ILE B CA  1 
ATOM   2830 C C   . ILE B 2 140 ? 118.171 111.300 132.631 1.00 28.72 ? 140 ILE B C   1 
ATOM   2831 O O   . ILE B 2 140 ? 117.831 111.455 131.452 1.00 41.11 ? 140 ILE B O   1 
ATOM   2832 C CB  . ILE B 2 140 ? 117.866 113.698 133.357 1.00 25.38 ? 140 ILE B CB  1 
ATOM   2833 C CG1 . ILE B 2 140 ? 118.392 114.792 134.291 1.00 24.45 ? 140 ILE B CG1 1 
ATOM   2834 C CG2 . ILE B 2 140 ? 116.435 113.332 133.715 1.00 28.09 ? 140 ILE B CG2 1 
ATOM   2835 C CD1 . ILE B 2 140 ? 117.871 116.175 133.975 1.00 30.54 ? 140 ILE B CD1 1 
ATOM   2836 N N   . LEU B 2 141 ? 118.032 110.148 133.278 1.00 28.60 ? 141 LEU B N   1 
ATOM   2837 C CA  . LEU B 2 141 ? 117.628 108.914 132.621 1.00 27.61 ? 141 LEU B CA  1 
ATOM   2838 C C   . LEU B 2 141 ? 116.127 108.720 132.758 1.00 29.50 ? 141 LEU B C   1 
ATOM   2839 O O   . LEU B 2 141 ? 115.573 108.838 133.855 1.00 45.03 ? 141 LEU B O   1 
ATOM   2840 C CB  . LEU B 2 141 ? 118.373 107.715 133.217 1.00 36.32 ? 141 LEU B CB  1 
ATOM   2841 C CG  . LEU B 2 141 ? 118.051 106.323 132.667 1.00 34.51 ? 141 LEU B CG  1 
ATOM   2842 C CD1 . LEU B 2 141 ? 118.444 106.213 131.205 1.00 37.20 ? 141 LEU B CD1 1 
ATOM   2843 C CD2 . LEU B 2 141 ? 118.755 105.265 133.491 1.00 35.90 ? 141 LEU B CD2 1 
ATOM   2844 N N   . PHE B 2 142 ? 115.480 108.416 131.636 1.00 22.63 ? 142 PHE B N   1 
ATOM   2845 C CA  . PHE B 2 142 ? 114.049 108.160 131.572 1.00 30.79 ? 142 PHE B CA  1 
ATOM   2846 C C   . PHE B 2 142 ? 113.817 106.735 131.094 1.00 35.08 ? 142 PHE B C   1 
ATOM   2847 O O   . PHE B 2 142 ? 114.472 106.273 130.155 1.00 35.84 ? 142 PHE B O   1 
ATOM   2848 C CB  . PHE B 2 142 ? 113.359 109.145 130.627 1.00 38.17 ? 142 PHE B CB  1 
ATOM   2849 C CG  . PHE B 2 142 ? 112.858 110.386 131.303 1.00 32.52 ? 142 PHE B CG  1 
ATOM   2850 C CD1 . PHE B 2 142 ? 113.713 111.196 132.025 1.00 30.59 ? 142 PHE B CD1 1 
ATOM   2851 C CD2 . PHE B 2 142 ? 111.532 110.752 131.199 1.00 32.13 ? 142 PHE B CD2 1 
ATOM   2852 C CE1 . PHE B 2 142 ? 113.247 112.338 132.642 1.00 27.79 ? 142 PHE B CE1 1 
ATOM   2853 C CE2 . PHE B 2 142 ? 111.064 111.890 131.814 1.00 37.83 ? 142 PHE B CE2 1 
ATOM   2854 C CZ  . PHE B 2 142 ? 111.923 112.685 132.534 1.00 31.93 ? 142 PHE B CZ  1 
ATOM   2855 N N   . LEU B 2 143 ? 112.882 106.044 131.743 1.00 38.77 ? 143 LEU B N   1 
ATOM   2856 C CA  . LEU B 2 143 ? 112.527 104.665 131.418 1.00 39.09 ? 143 LEU B CA  1 
ATOM   2857 C C   . LEU B 2 143 ? 111.077 104.664 130.952 1.00 39.76 ? 143 LEU B C   1 
ATOM   2858 O O   . LEU B 2 143 ? 110.160 104.508 131.764 1.00 44.95 ? 143 LEU B O   1 
ATOM   2859 C CB  . LEU B 2 143 ? 112.724 103.752 132.627 1.00 39.63 ? 143 LEU B CB  1 
ATOM   2860 C CG  . LEU B 2 143 ? 114.144 103.700 133.203 1.00 40.79 ? 143 LEU B CG  1 
ATOM   2861 C CD1 . LEU B 2 143 ? 114.132 103.125 134.604 1.00 40.92 ? 143 LEU B CD1 1 
ATOM   2862 C CD2 . LEU B 2 143 ? 115.069 102.898 132.312 1.00 42.62 ? 143 LEU B CD2 1 
ATOM   2863 N N   . ASN B 2 144 ? 110.875 104.824 129.649 1.00 38.95 ? 144 ASN B N   1 
ATOM   2864 C CA  . ASN B 2 144 ? 109.562 105.081 129.076 1.00 37.43 ? 144 ASN B CA  1 
ATOM   2865 C C   . ASN B 2 144 ? 108.758 103.797 128.917 1.00 41.19 ? 144 ASN B C   1 
ATOM   2866 O O   . ASN B 2 144 ? 109.292 102.686 128.948 1.00 41.59 ? 144 ASN B O   1 
ATOM   2867 C CB  . ASN B 2 144 ? 109.692 105.767 127.713 1.00 33.77 ? 144 ASN B CB  1 
ATOM   2868 C CG  . ASN B 2 144 ? 109.612 107.271 127.810 1.00 36.24 ? 144 ASN B CG  1 
ATOM   2869 O OD1 . ASN B 2 144 ? 110.014 107.862 128.810 1.00 42.60 ? 144 ASN B OD1 1 
ATOM   2870 N ND2 . ASN B 2 144 ? 109.089 107.902 126.767 1.00 35.98 ? 144 ASN B ND2 1 
ATOM   2871 N N   . LYS B 2 145 ? 107.447 103.976 128.744 1.00 49.64 ? 145 LYS B N   1 
ATOM   2872 C CA  . LYS B 2 145 ? 106.516 102.910 128.376 1.00 52.52 ? 145 LYS B CA  1 
ATOM   2873 C C   . LYS B 2 145 ? 106.526 101.785 129.417 1.00 51.50 ? 145 LYS B C   1 
ATOM   2874 O O   . LYS B 2 145 ? 106.771 100.616 129.119 1.00 51.21 ? 145 LYS B O   1 
ATOM   2875 C CB  . LYS B 2 145 ? 106.844 102.369 126.979 1.00 50.51 ? 145 LYS B CB  1 
ATOM   2876 C CG  . LYS B 2 145 ? 106.588 103.364 125.861 1.00 50.07 ? 145 LYS B CG  1 
ATOM   2877 C CD  . LYS B 2 145 ? 106.809 102.735 124.496 1.00 50.46 ? 145 LYS B CD  1 
ATOM   2878 C CE  . LYS B 2 145 ? 106.648 103.755 123.383 1.00 50.24 ? 145 LYS B CE  1 
ATOM   2879 N NZ  . LYS B 2 145 ? 107.153 103.243 122.081 1.00 47.85 ? 145 LYS B NZ  1 
ATOM   2880 N N   . GLN B 2 146 ? 106.242 102.178 130.659 1.00 52.45 ? 146 GLN B N   1 
ATOM   2881 C CA  . GLN B 2 146 ? 106.147 101.194 131.731 1.00 55.11 ? 146 GLN B CA  1 
ATOM   2882 C C   . GLN B 2 146 ? 104.821 100.441 131.698 1.00 58.55 ? 146 GLN B C   1 
ATOM   2883 O O   . GLN B 2 146 ? 104.748 99.306  132.184 1.00 62.23 ? 146 GLN B O   1 
ATOM   2884 C CB  . GLN B 2 146 ? 106.366 101.873 133.088 1.00 52.62 ? 146 GLN B CB  1 
ATOM   2885 C CG  . GLN B 2 146 ? 105.325 102.912 133.501 1.00 56.10 ? 146 GLN B CG  1 
ATOM   2886 C CD  . GLN B 2 146 ? 105.429 103.278 134.971 1.00 58.69 ? 146 GLN B CD  1 
ATOM   2887 O OE1 . GLN B 2 146 ? 105.638 102.417 135.825 1.00 56.48 ? 146 GLN B OE1 1 
ATOM   2888 N NE2 . GLN B 2 146 ? 105.286 104.563 135.272 1.00 56.10 ? 146 GLN B NE2 1 
ATOM   2889 N N   . ASP B 2 147 ? 103.772 101.037 131.122 1.00 58.85 ? 147 ASP B N   1 
ATOM   2890 C CA  . ASP B 2 147 ? 102.499 100.327 131.021 1.00 59.25 ? 147 ASP B CA  1 
ATOM   2891 C C   . ASP B 2 147 ? 102.630 99.088  130.147 1.00 62.15 ? 147 ASP B C   1 
ATOM   2892 O O   . ASP B 2 147 ? 102.140 98.012  130.511 1.00 63.14 ? 147 ASP B O   1 
ATOM   2893 C CB  . ASP B 2 147 ? 101.405 101.239 130.461 1.00 61.14 ? 147 ASP B CB  1 
ATOM   2894 C CG  . ASP B 2 147 ? 101.365 102.595 131.130 1.00 62.62 ? 147 ASP B CG  1 
ATOM   2895 O OD1 . ASP B 2 147 ? 101.719 102.686 132.323 1.00 60.56 ? 147 ASP B OD1 1 
ATOM   2896 O OD2 . ASP B 2 147 ? 100.969 103.568 130.455 1.00 62.03 ? 147 ASP B OD2 1 
ATOM   2897 N N   . LEU B 2 148 ? 103.286 99.222  128.991 1.00 64.42 ? 148 LEU B N   1 
ATOM   2898 C CA  . LEU B 2 148 ? 103.466 98.080  128.102 1.00 64.77 ? 148 LEU B CA  1 
ATOM   2899 C C   . LEU B 2 148 ? 104.320 97.006  128.762 1.00 67.51 ? 148 LEU B C   1 
ATOM   2900 O O   . LEU B 2 148 ? 104.074 95.809  128.580 1.00 68.44 ? 148 LEU B O   1 
ATOM   2901 C CB  . LEU B 2 148 ? 104.092 98.534  126.785 1.00 58.44 ? 148 LEU B CB  1 
ATOM   2902 N N   . LEU B 2 149 ? 105.328 97.418  129.533 1.00 63.59 ? 149 LEU B N   1 
ATOM   2903 C CA  . LEU B 2 149 ? 106.114 96.463  130.307 1.00 63.97 ? 149 LEU B CA  1 
ATOM   2904 C C   . LEU B 2 149 ? 105.230 95.715  131.297 1.00 65.17 ? 149 LEU B C   1 
ATOM   2905 O O   . LEU B 2 149 ? 105.364 94.497  131.474 1.00 64.95 ? 149 LEU B O   1 
ATOM   2906 C CB  . LEU B 2 149 ? 107.246 97.196  131.030 1.00 60.53 ? 149 LEU B CB  1 
ATOM   2907 C CG  . LEU B 2 149 ? 108.018 96.456  132.125 1.00 56.87 ? 149 LEU B CG  1 
ATOM   2908 C CD1 . LEU B 2 149 ? 109.500 96.762  132.023 1.00 58.19 ? 149 LEU B CD1 1 
ATOM   2909 C CD2 . LEU B 2 149 ? 107.499 96.839  133.501 1.00 58.08 ? 149 LEU B CD2 1 
ATOM   2910 N N   . ALA B 2 150 ? 104.320 96.436  131.957 1.00 64.49 ? 150 ALA B N   1 
ATOM   2911 C CA  . ALA B 2 150 ? 103.407 95.795  132.897 1.00 63.21 ? 150 ALA B CA  1 
ATOM   2912 C C   . ALA B 2 150 ? 102.523 94.769  132.198 1.00 62.20 ? 150 ALA B C   1 
ATOM   2913 O O   . ALA B 2 150 ? 102.357 93.646  132.691 1.00 62.38 ? 150 ALA B O   1 
ATOM   2914 C CB  . ALA B 2 150 ? 102.549 96.847  133.598 1.00 58.91 ? 150 ALA B CB  1 
ATOM   2915 N N   . GLU B 2 151 ? 101.956 95.125  131.041 1.00 64.41 ? 151 GLU B N   1 
ATOM   2916 C CA  . GLU B 2 151 ? 101.104 94.159  130.343 1.00 67.36 ? 151 GLU B CA  1 
ATOM   2917 C C   . GLU B 2 151 ? 101.915 92.958  129.877 1.00 67.76 ? 151 GLU B C   1 
ATOM   2918 O O   . GLU B 2 151 ? 101.452 91.815  129.971 1.00 65.64 ? 151 GLU B O   1 
ATOM   2919 C CB  . GLU B 2 151 ? 100.363 94.771  129.145 1.00 69.04 ? 151 GLU B CB  1 
ATOM   2920 C CG  . GLU B 2 151 ? 100.004 96.238  129.209 1.00 67.40 ? 151 GLU B CG  1 
ATOM   2921 C CD  . GLU B 2 151 ? 98.987  96.630  128.157 1.00 67.41 ? 151 GLU B CD  1 
ATOM   2922 O OE1 . GLU B 2 151 ? 99.328  96.592  126.956 1.00 66.12 ? 151 GLU B OE1 1 
ATOM   2923 O OE2 . GLU B 2 151 ? 97.847  96.976  128.530 1.00 68.59 ? 151 GLU B OE2 1 
ATOM   2924 N N   . LYS B 2 152 ? 103.131 93.192  129.378 1.00 70.99 ? 152 LYS B N   1 
ATOM   2925 C CA  . LYS B 2 152 ? 103.946 92.086  128.890 1.00 73.27 ? 152 LYS B CA  1 
ATOM   2926 C C   . LYS B 2 152 ? 104.317 91.129  130.016 1.00 73.67 ? 152 LYS B C   1 
ATOM   2927 O O   . LYS B 2 152 ? 104.237 89.907  129.846 1.00 70.57 ? 152 LYS B O   1 
ATOM   2928 C CB  . LYS B 2 152 ? 105.204 92.621  128.207 1.00 69.39 ? 152 LYS B CB  1 
ATOM   2929 C CG  . LYS B 2 152 ? 105.907 91.587  127.325 1.00 70.72 ? 152 LYS B CG  1 
ATOM   2930 C CD  . LYS B 2 152 ? 106.889 92.201  126.327 1.00 72.50 ? 152 LYS B CD  1 
ATOM   2931 C CE  . LYS B 2 152 ? 106.194 92.971  125.208 1.00 73.10 ? 152 LYS B CE  1 
ATOM   2932 N NZ  . LYS B 2 152 ? 107.156 93.423  124.165 1.00 70.85 ? 152 LYS B NZ  1 
ATOM   2933 N N   . VAL B 2 153 ? 104.717 91.658  131.175 1.00 70.58 ? 153 VAL B N   1 
ATOM   2934 C CA  . VAL B 2 153 ? 105.125 90.777  132.266 1.00 72.48 ? 153 VAL B CA  1 
ATOM   2935 C C   . VAL B 2 153 ? 103.911 90.089  132.885 1.00 72.67 ? 153 VAL B C   1 
ATOM   2936 O O   . VAL B 2 153 ? 104.012 88.956  133.371 1.00 70.91 ? 153 VAL B O   1 
ATOM   2937 C CB  . VAL B 2 153 ? 105.957 91.548  133.311 1.00 67.97 ? 153 VAL B CB  1 
ATOM   2938 C CG1 . VAL B 2 153 ? 105.111 92.541  134.080 1.00 66.36 ? 153 VAL B CG1 1 
ATOM   2939 C CG2 . VAL B 2 153 ? 106.645 90.579  134.265 1.00 67.98 ? 153 VAL B CG2 1 
ATOM   2940 N N   . LEU B 2 154 ? 102.747 90.749  132.882 1.00 73.73 ? 154 LEU B N   1 
ATOM   2941 C CA  . LEU B 2 154 ? 101.540 90.091  133.376 1.00 70.54 ? 154 LEU B CA  1 
ATOM   2942 C C   . LEU B 2 154 ? 101.023 89.030  132.414 1.00 70.26 ? 154 LEU B C   1 
ATOM   2943 O O   . LEU B 2 154 ? 100.350 88.091  132.853 1.00 70.83 ? 154 LEU B O   1 
ATOM   2944 C CB  . LEU B 2 154 ? 100.435 91.117  133.641 1.00 69.43 ? 154 LEU B CB  1 
ATOM   2945 C CG  . LEU B 2 154 ? 100.282 91.573  135.094 1.00 70.54 ? 154 LEU B CG  1 
ATOM   2946 C CD1 . LEU B 2 154 ? 101.387 92.541  135.479 1.00 70.51 ? 154 LEU B CD1 1 
ATOM   2947 C CD2 . LEU B 2 154 ? 98.915  92.204  135.313 1.00 68.88 ? 154 LEU B CD2 1 
ATOM   2948 N N   . ALA B 2 155 ? 101.311 89.159  131.116 1.00 71.61 ? 155 ALA B N   1 
ATOM   2949 C CA  . ALA B 2 155 ? 100.882 88.143  130.161 1.00 75.77 ? 155 ALA B CA  1 
ATOM   2950 C C   . ALA B 2 155 ? 101.546 86.802  130.449 1.00 75.72 ? 155 ALA B C   1 
ATOM   2951 O O   . ALA B 2 155 ? 100.913 85.747  130.322 1.00 74.17 ? 155 ALA B O   1 
ATOM   2952 C CB  . ALA B 2 155 ? 101.193 88.599  128.736 1.00 74.43 ? 155 ALA B CB  1 
ATOM   2953 N N   . GLY B 2 156 ? 102.819 86.822  130.836 1.00 72.06 ? 156 GLY B N   1 
ATOM   2954 C CA  . GLY B 2 156 ? 103.535 85.598  131.131 1.00 72.12 ? 156 GLY B CA  1 
ATOM   2955 C C   . GLY B 2 156 ? 104.087 84.874  129.926 1.00 75.00 ? 156 GLY B C   1 
ATOM   2956 O O   . GLY B 2 156 ? 104.517 83.724  130.055 1.00 74.22 ? 156 GLY B O   1 
ATOM   2957 N N   . LYS B 2 157 ? 104.092 85.509  128.754 1.00 76.93 ? 157 LYS B N   1 
ATOM   2958 C CA  . LYS B 2 157 ? 104.642 84.896  127.550 1.00 76.23 ? 157 LYS B CA  1 
ATOM   2959 C C   . LYS B 2 157 ? 106.160 85.045  127.502 1.00 77.04 ? 157 LYS B C   1 
ATOM   2960 O O   . LYS B 2 157 ? 106.887 84.050  127.416 1.00 76.39 ? 157 LYS B O   1 
ATOM   2961 C CB  . LYS B 2 157 ? 103.999 85.519  126.305 1.00 74.32 ? 157 LYS B CB  1 
ATOM   2962 N N   . SER B 2 158 ? 106.648 86.280  127.558 1.00 81.82 ? 158 SER B N   1 
ATOM   2963 C CA  . SER B 2 158 ? 108.082 86.520  127.531 1.00 82.42 ? 158 SER B CA  1 
ATOM   2964 C C   . SER B 2 158 ? 108.713 86.155  128.870 1.00 83.11 ? 158 SER B C   1 
ATOM   2965 O O   . SER B 2 158 ? 108.103 86.304  129.932 1.00 80.85 ? 158 SER B O   1 
ATOM   2966 C CB  . SER B 2 158 ? 108.373 87.983  127.203 1.00 80.86 ? 158 SER B CB  1 
ATOM   2967 O OG  . SER B 2 158 ? 107.921 88.833  128.241 1.00 81.47 ? 158 SER B OG  1 
ATOM   2968 N N   . LYS B 2 159 ? 109.954 85.673  128.803 1.00 89.40 ? 159 LYS B N   1 
ATOM   2969 C CA  . LYS B 2 159 ? 110.733 85.302  129.975 1.00 88.30 ? 159 LYS B CA  1 
ATOM   2970 C C   . LYS B 2 159 ? 112.041 86.080  129.976 1.00 87.13 ? 159 LYS B C   1 
ATOM   2971 O O   . LYS B 2 159 ? 112.702 86.219  128.943 1.00 85.33 ? 159 LYS B O   1 
ATOM   2972 C CB  . LYS B 2 159 ? 111.007 83.787  130.008 1.00 87.77 ? 159 LYS B CB  1 
ATOM   2973 C CG  . LYS B 2 159 ? 111.761 83.247  128.788 1.00 86.03 ? 159 LYS B CG  1 
ATOM   2974 C CD  . LYS B 2 159 ? 112.004 81.735  128.847 1.00 86.87 ? 159 LYS B CD  1 
ATOM   2975 C CE  . LYS B 2 159 ? 110.716 80.915  128.831 1.00 88.67 ? 159 LYS B CE  1 
ATOM   2976 N NZ  . LYS B 2 159 ? 110.992 79.452  128.791 1.00 87.56 ? 159 LYS B NZ  1 
ATOM   2977 N N   . ILE B 2 160 ? 112.408 86.584  131.151 1.00 81.93 ? 160 ILE B N   1 
ATOM   2978 C CA  . ILE B 2 160 ? 113.600 87.415  131.272 1.00 82.25 ? 160 ILE B CA  1 
ATOM   2979 C C   . ILE B 2 160 ? 114.866 86.572  131.406 1.00 82.91 ? 160 ILE B C   1 
ATOM   2980 O O   . ILE B 2 160 ? 115.959 87.050  131.086 1.00 82.16 ? 160 ILE B O   1 
ATOM   2981 C CB  . ILE B 2 160 ? 113.471 88.390  132.460 1.00 83.68 ? 160 ILE B CB  1 
ATOM   2982 C CG1 . ILE B 2 160 ? 112.079 89.043  132.516 1.00 82.07 ? 160 ILE B CG1 1 
ATOM   2983 C CG2 . ILE B 2 160 ? 114.568 89.453  132.404 1.00 81.89 ? 160 ILE B CG2 1 
ATOM   2984 C CD1 . ILE B 2 160 ? 111.681 89.807  131.261 1.00 80.23 ? 160 ILE B CD1 1 
ATOM   2985 N N   . GLU B 2 161 ? 114.746 85.328  131.876 1.00 89.34 ? 161 GLU B N   1 
ATOM   2986 C CA  . GLU B 2 161 ? 115.924 84.481  132.031 1.00 90.58 ? 161 GLU B CA  1 
ATOM   2987 C C   . GLU B 2 161 ? 116.579 84.178  130.689 1.00 91.01 ? 161 GLU B C   1 
ATOM   2988 O O   . GLU B 2 161 ? 117.797 83.968  130.629 1.00 89.27 ? 161 GLU B O   1 
ATOM   2989 C CB  . GLU B 2 161 ? 115.542 83.180  132.738 1.00 87.81 ? 161 GLU B CB  1 
ATOM   2990 N N   . ASP B 2 162 ? 115.795 84.148  129.608 1.00 87.24 ? 162 ASP B N   1 
ATOM   2991 C CA  . ASP B 2 162 ? 116.361 83.879  128.290 1.00 86.73 ? 162 ASP B CA  1 
ATOM   2992 C C   . ASP B 2 162 ? 117.346 84.966  127.879 1.00 85.81 ? 162 ASP B C   1 
ATOM   2993 O O   . ASP B 2 162 ? 118.417 84.669  127.336 1.00 86.18 ? 162 ASP B O   1 
ATOM   2994 C CB  . ASP B 2 162 ? 115.240 83.753  127.258 1.00 85.08 ? 162 ASP B CB  1 
ATOM   2995 C CG  . ASP B 2 162 ? 115.753 83.372  125.882 1.00 83.98 ? 162 ASP B CG  1 
ATOM   2996 O OD1 . ASP B 2 162 ? 116.846 82.772  125.797 1.00 84.31 ? 162 ASP B OD1 1 
ATOM   2997 O OD2 . ASP B 2 162 ? 115.063 83.671  124.885 1.00 81.97 ? 162 ASP B OD2 1 
ATOM   2998 N N   . TYR B 2 163 ? 117.005 86.229  128.132 1.00 82.38 ? 163 TYR B N   1 
ATOM   2999 C CA  . TYR B 2 163 ? 117.878 87.355  127.819 1.00 81.16 ? 163 TYR B CA  1 
ATOM   3000 C C   . TYR B 2 163 ? 118.876 87.648  128.930 1.00 79.31 ? 163 TYR B C   1 
ATOM   3001 O O   . TYR B 2 163 ? 120.068 87.819  128.654 1.00 80.71 ? 163 TYR B O   1 
ATOM   3002 C CB  . TYR B 2 163 ? 117.061 88.627  127.545 1.00 79.38 ? 163 TYR B CB  1 
ATOM   3003 C CG  . TYR B 2 163 ? 115.874 88.461  126.615 1.00 83.42 ? 163 TYR B CG  1 
ATOM   3004 C CD1 . TYR B 2 163 ? 114.650 87.998  127.083 1.00 83.72 ? 163 TYR B CD1 1 
ATOM   3005 C CD2 . TYR B 2 163 ? 115.966 88.818  125.277 1.00 79.50 ? 163 TYR B CD2 1 
ATOM   3006 C CE1 . TYR B 2 163 ? 113.565 87.861  126.238 1.00 82.81 ? 163 TYR B CE1 1 
ATOM   3007 C CE2 . TYR B 2 163 ? 114.886 88.684  124.424 1.00 78.32 ? 163 TYR B CE2 1 
ATOM   3008 C CZ  . TYR B 2 163 ? 113.688 88.208  124.911 1.00 81.04 ? 163 TYR B CZ  1 
ATOM   3009 O OH  . TYR B 2 163 ? 112.609 88.075  124.069 1.00 80.00 ? 163 TYR B OH  1 
ATOM   3010 N N   . PHE B 2 164 ? 118.412 87.705  130.174 1.00 78.69 ? 164 PHE B N   1 
ATOM   3011 C CA  . PHE B 2 164 ? 119.243 88.048  131.329 1.00 79.73 ? 164 PHE B CA  1 
ATOM   3012 C C   . PHE B 2 164 ? 119.285 86.867  132.291 1.00 81.09 ? 164 PHE B C   1 
ATOM   3013 O O   . PHE B 2 164 ? 118.332 86.686  133.074 1.00 76.44 ? 164 PHE B O   1 
ATOM   3014 C CB  . PHE B 2 164 ? 118.685 89.284  132.033 1.00 79.20 ? 164 PHE B CB  1 
ATOM   3015 C CG  . PHE B 2 164 ? 118.735 90.530  131.197 1.00 79.92 ? 164 PHE B CG  1 
ATOM   3016 C CD1 . PHE B 2 164 ? 119.851 91.349  131.214 1.00 79.30 ? 164 PHE B CD1 1 
ATOM   3017 C CD2 . PHE B 2 164 ? 117.664 90.883  130.394 1.00 79.78 ? 164 PHE B CD2 1 
ATOM   3018 C CE1 . PHE B 2 164 ? 119.898 92.496  130.444 1.00 77.57 ? 164 PHE B CE1 1 
ATOM   3019 C CE2 . PHE B 2 164 ? 117.706 92.028  129.623 1.00 79.48 ? 164 PHE B CE2 1 
ATOM   3020 C CZ  . PHE B 2 164 ? 118.824 92.835  129.649 1.00 77.75 ? 164 PHE B CZ  1 
ATOM   3021 N N   . PRO B 2 165 ? 120.332 86.029  132.289 1.00 89.09 ? 165 PRO B N   1 
ATOM   3022 C CA  . PRO B 2 165 ? 120.355 84.904  133.241 1.00 88.59 ? 165 PRO B CA  1 
ATOM   3023 C C   . PRO B 2 165 ? 120.389 85.332  134.699 1.00 86.91 ? 165 PRO B C   1 
ATOM   3024 O O   . PRO B 2 165 ? 120.023 84.529  135.567 1.00 84.54 ? 165 PRO B O   1 
ATOM   3025 C CB  . PRO B 2 165 ? 121.630 84.132  132.860 1.00 87.12 ? 165 PRO B CB  1 
ATOM   3026 C CG  . PRO B 2 165 ? 122.048 84.655  131.534 1.00 85.07 ? 165 PRO B CG  1 
ATOM   3027 C CD  . PRO B 2 165 ? 121.539 86.049  131.444 1.00 86.52 ? 165 PRO B CD  1 
ATOM   3028 N N   . GLU B 2 166 ? 120.809 86.560  134.998 1.00 86.26 ? 166 GLU B N   1 
ATOM   3029 C CA  . GLU B 2 166 ? 120.905 87.025  136.375 1.00 86.08 ? 166 GLU B CA  1 
ATOM   3030 C C   . GLU B 2 166 ? 119.552 87.362  136.991 1.00 85.72 ? 166 GLU B C   1 
ATOM   3031 O O   . GLU B 2 166 ? 119.485 87.578  138.206 1.00 85.08 ? 166 GLU B O   1 
ATOM   3032 C CB  . GLU B 2 166 ? 121.819 88.252  136.448 1.00 84.20 ? 166 GLU B CB  1 
ATOM   3033 C CG  . GLU B 2 166 ? 123.271 87.976  136.071 1.00 85.31 ? 166 GLU B CG  1 
ATOM   3034 C CD  . GLU B 2 166 ? 123.983 87.082  137.069 1.00 87.34 ? 166 GLU B CD  1 
ATOM   3035 O OE1 . GLU B 2 166 ? 123.657 87.149  138.272 1.00 87.93 ? 166 GLU B OE1 1 
ATOM   3036 O OE2 . GLU B 2 166 ? 124.871 86.311  136.648 1.00 86.58 ? 166 GLU B OE2 1 
ATOM   3037 N N   . PHE B 2 167 ? 118.479 87.417  136.198 1.00 79.89 ? 167 PHE B N   1 
ATOM   3038 C CA  . PHE B 2 167 ? 117.159 87.681  136.757 1.00 80.47 ? 167 PHE B CA  1 
ATOM   3039 C C   . PHE B 2 167 ? 116.586 86.471  137.484 1.00 82.26 ? 167 PHE B C   1 
ATOM   3040 O O   . PHE B 2 167 ? 115.766 86.645  138.392 1.00 78.47 ? 167 PHE B O   1 
ATOM   3041 C CB  . PHE B 2 167 ? 116.195 88.122  135.654 1.00 76.19 ? 167 PHE B CB  1 
ATOM   3042 C CG  . PHE B 2 167 ? 114.833 88.510  136.158 1.00 77.66 ? 167 PHE B CG  1 
ATOM   3043 C CD1 . PHE B 2 167 ? 114.603 89.780  136.658 1.00 74.83 ? 167 PHE B CD1 1 
ATOM   3044 C CD2 . PHE B 2 167 ? 113.783 87.607  136.135 1.00 79.88 ? 167 PHE B CD2 1 
ATOM   3045 C CE1 . PHE B 2 167 ? 113.353 90.142  137.124 1.00 74.86 ? 167 PHE B CE1 1 
ATOM   3046 C CE2 . PHE B 2 167 ? 112.531 87.964  136.601 1.00 77.08 ? 167 PHE B CE2 1 
ATOM   3047 C CZ  . PHE B 2 167 ? 112.317 89.233  137.096 1.00 74.09 ? 167 PHE B CZ  1 
ATOM   3048 N N   . ALA B 2 168 ? 116.991 85.255  137.102 1.00 83.36 ? 168 ALA B N   1 
ATOM   3049 C CA  . ALA B 2 168 ? 116.446 84.058  137.736 1.00 81.04 ? 168 ALA B CA  1 
ATOM   3050 C C   . ALA B 2 168 ? 116.766 84.027  139.224 1.00 81.14 ? 168 ALA B C   1 
ATOM   3051 O O   . ALA B 2 168 ? 115.903 83.689  140.044 1.00 78.32 ? 168 ALA B O   1 
ATOM   3052 C CB  . ALA B 2 168 ? 116.988 82.807  137.046 1.00 79.68 ? 168 ALA B CB  1 
ATOM   3053 N N   . ARG B 2 169 ? 117.998 84.378  139.589 1.00 82.17 ? 169 ARG B N   1 
ATOM   3054 C CA  . ARG B 2 169 ? 118.417 84.514  140.982 1.00 81.47 ? 169 ARG B CA  1 
ATOM   3055 C C   . ARG B 2 169 ? 118.634 85.997  141.254 1.00 80.89 ? 169 ARG B C   1 
ATOM   3056 O O   . ARG B 2 169 ? 119.681 86.553  140.903 1.00 80.09 ? 169 ARG B O   1 
ATOM   3057 C CB  . ARG B 2 169 ? 119.677 83.698  141.277 1.00 82.34 ? 169 ARG B CB  1 
ATOM   3058 C CG  . ARG B 2 169 ? 120.766 83.744  140.195 1.00 81.34 ? 169 ARG B CG  1 
ATOM   3059 C CD  . ARG B 2 169 ? 122.118 83.202  140.673 1.00 82.61 ? 169 ARG B CD  1 
ATOM   3060 N NE  . ARG B 2 169 ? 122.596 83.832  141.901 1.00 83.93 ? 169 ARG B NE  1 
ATOM   3061 C CZ  . ARG B 2 169 ? 123.040 85.079  141.993 1.00 81.96 ? 169 ARG B CZ  1 
ATOM   3062 N NH1 . ARG B 2 169 ? 123.104 85.878  140.938 1.00 79.41 ? 169 ARG B NH1 1 
ATOM   3063 N NH2 . ARG B 2 169 ? 123.430 85.541  143.178 1.00 79.84 ? 169 ARG B NH2 1 
ATOM   3064 N N   . TYR B 2 170 ? 117.639 86.632  141.871 1.00 76.72 ? 170 TYR B N   1 
ATOM   3065 C CA  . TYR B 2 170 ? 117.673 88.051  142.191 1.00 75.30 ? 170 TYR B CA  1 
ATOM   3066 C C   . TYR B 2 170 ? 117.256 88.251  143.639 1.00 74.91 ? 170 TYR B C   1 
ATOM   3067 O O   . TYR B 2 170 ? 116.401 87.532  144.162 1.00 75.84 ? 170 TYR B O   1 
ATOM   3068 C CB  . TYR B 2 170 ? 116.746 88.857  141.261 1.00 72.66 ? 170 TYR B CB  1 
ATOM   3069 C CG  . TYR B 2 170 ? 116.878 90.362  141.376 1.00 75.27 ? 170 TYR B CG  1 
ATOM   3070 C CD1 . TYR B 2 170 ? 118.110 90.991  141.243 1.00 74.85 ? 170 TYR B CD1 1 
ATOM   3071 C CD2 . TYR B 2 170 ? 115.764 91.153  141.620 1.00 74.05 ? 170 TYR B CD2 1 
ATOM   3072 C CE1 . TYR B 2 170 ? 118.227 92.363  141.349 1.00 70.98 ? 170 TYR B CE1 1 
ATOM   3073 C CE2 . TYR B 2 170 ? 115.872 92.525  141.727 1.00 73.86 ? 170 TYR B CE2 1 
ATOM   3074 C CZ  . TYR B 2 170 ? 117.105 93.124  141.591 1.00 71.54 ? 170 TYR B CZ  1 
ATOM   3075 O OH  . TYR B 2 170 ? 117.217 94.490  141.698 1.00 70.93 ? 170 TYR B OH  1 
ATOM   3076 N N   . THR B 2 171 ? 117.868 89.242  144.280 1.00 74.52 ? 171 THR B N   1 
ATOM   3077 C CA  . THR B 2 171 ? 117.603 89.536  145.681 1.00 76.41 ? 171 THR B CA  1 
ATOM   3078 C C   . THR B 2 171 ? 116.315 90.340  145.797 1.00 74.53 ? 171 THR B C   1 
ATOM   3079 O O   . THR B 2 171 ? 116.073 91.256  145.004 1.00 71.89 ? 171 THR B O   1 
ATOM   3080 C CB  . THR B 2 171 ? 118.769 90.306  146.303 1.00 76.47 ? 171 THR B CB  1 
ATOM   3081 O OG1 . THR B 2 171 ? 120.000 89.632  146.014 1.00 76.20 ? 171 THR B OG1 1 
ATOM   3082 C CG2 . THR B 2 171 ? 118.599 90.417  147.815 1.00 76.05 ? 171 THR B CG2 1 
ATOM   3083 N N   . THR B 2 172 ? 115.496 89.992  146.778 1.00 73.91 ? 172 THR B N   1 
ATOM   3084 C CA  . THR B 2 172 ? 114.240 90.699  146.981 1.00 74.63 ? 172 THR B CA  1 
ATOM   3085 C C   . THR B 2 172 ? 114.529 92.132  147.429 1.00 74.57 ? 172 THR B C   1 
ATOM   3086 O O   . THR B 2 172 ? 115.278 92.327  148.394 1.00 73.61 ? 172 THR B O   1 
ATOM   3087 C CB  . THR B 2 172 ? 113.388 89.985  148.029 1.00 75.10 ? 172 THR B CB  1 
ATOM   3088 O OG1 . THR B 2 172 ? 114.144 89.822  149.237 1.00 76.93 ? 172 THR B OG1 1 
ATOM   3089 C CG2 . THR B 2 172 ? 112.948 88.619  147.523 1.00 71.53 ? 172 THR B CG2 1 
ATOM   3090 N N   . PRO B 2 173 ? 113.962 93.168  146.768 1.00 69.81 ? 173 PRO B N   1 
ATOM   3091 C CA  . PRO B 2 173 ? 114.236 94.545  147.221 1.00 70.76 ? 173 PRO B CA  1 
ATOM   3092 C C   . PRO B 2 173 ? 113.398 94.930  148.438 1.00 71.33 ? 173 PRO B C   1 
ATOM   3093 O O   . PRO B 2 173 ? 112.525 95.802  148.384 1.00 69.73 ? 173 PRO B O   1 
ATOM   3094 C CB  . PRO B 2 173 ? 113.897 95.370  145.973 1.00 67.10 ? 173 PRO B CB  1 
ATOM   3095 C CG  . PRO B 2 173 ? 112.795 94.624  145.341 1.00 66.72 ? 173 PRO B CG  1 
ATOM   3096 C CD  . PRO B 2 173 ? 113.072 93.166  145.589 1.00 65.01 ? 173 PRO B CD  1 
ATOM   3097 N N   . GLU B 2 174 ? 113.660 94.257  149.562 1.00 68.97 ? 174 GLU B N   1 
ATOM   3098 C CA  . GLU B 2 174 ? 112.895 94.514  150.778 1.00 69.04 ? 174 GLU B CA  1 
ATOM   3099 C C   . GLU B 2 174 ? 113.137 95.924  151.302 1.00 68.55 ? 174 GLU B C   1 
ATOM   3100 O O   . GLU B 2 174 ? 112.192 96.610  151.711 1.00 64.74 ? 174 GLU B O   1 
ATOM   3101 C CB  . GLU B 2 174 ? 113.251 93.480  151.846 1.00 67.07 ? 174 GLU B CB  1 
ATOM   3102 N N   . ASP B 2 175 ? 114.395 96.372  151.305 1.00 73.35 ? 175 ASP B N   1 
ATOM   3103 C CA  . ASP B 2 175 ? 114.704 97.704  151.818 1.00 75.12 ? 175 ASP B CA  1 
ATOM   3104 C C   . ASP B 2 175 ? 114.060 98.789  150.964 1.00 77.18 ? 175 ASP B C   1 
ATOM   3105 O O   . ASP B 2 175 ? 113.516 99.765  151.493 1.00 75.82 ? 175 ASP B O   1 
ATOM   3106 C CB  . ASP B 2 175 ? 116.218 97.902  151.881 1.00 75.05 ? 175 ASP B CB  1 
ATOM   3107 C CG  . ASP B 2 175 ? 116.611 99.191  152.581 1.00 75.80 ? 175 ASP B CG  1 
ATOM   3108 O OD1 . ASP B 2 175 ? 115.749 99.798  153.251 1.00 74.49 ? 175 ASP B OD1 1 
ATOM   3109 O OD2 . ASP B 2 175 ? 117.785 99.598  152.461 1.00 75.15 ? 175 ASP B OD2 1 
ATOM   3110 N N   . ALA B 2 176 ? 114.112 98.638  149.643 1.00 73.78 ? 176 ALA B N   1 
ATOM   3111 C CA  . ALA B 2 176 ? 113.512 99.624  148.758 1.00 71.39 ? 176 ALA B CA  1 
ATOM   3112 C C   . ALA B 2 176 ? 111.996 99.625  148.910 1.00 71.77 ? 176 ALA B C   1 
ATOM   3113 O O   . ALA B 2 176 ? 111.346 98.576  148.910 1.00 71.42 ? 176 ALA B O   1 
ATOM   3114 C CB  . ALA B 2 176 ? 113.891 99.338  147.306 1.00 69.67 ? 176 ALA B CB  1 
ATOM   3115 N N   . THR B 2 177 ? 111.432 100.826 149.035 1.00 70.84 ? 177 THR B N   1 
ATOM   3116 C CA  . THR B 2 177 ? 110.001 100.981 149.247 1.00 71.15 ? 177 THR B CA  1 
ATOM   3117 C C   . THR B 2 177 ? 109.288 100.906 147.899 1.00 69.64 ? 177 THR B C   1 
ATOM   3118 O O   . THR B 2 177 ? 109.649 101.665 146.986 1.00 67.11 ? 177 THR B O   1 
ATOM   3119 C CB  . THR B 2 177 ? 109.699 102.308 149.929 1.00 70.33 ? 177 THR B CB  1 
ATOM   3120 O OG1 . THR B 2 177 ? 110.267 103.383 149.169 1.00 67.31 ? 177 THR B OG1 1 
ATOM   3121 C CG2 . THR B 2 177 ? 110.268 102.327 151.342 1.00 67.76 ? 177 THR B CG2 1 
ATOM   3122 N N   . PRO B 2 178 ? 108.290 100.037 147.716 1.00 75.27 ? 178 PRO B N   1 
ATOM   3123 C CA  . PRO B 2 178 ? 107.589 100.005 146.432 1.00 73.68 ? 178 PRO B CA  1 
ATOM   3124 C C   . PRO B 2 178 ? 106.440 101.000 146.406 1.00 73.07 ? 178 PRO B C   1 
ATOM   3125 O O   . PRO B 2 178 ? 106.082 101.608 147.416 1.00 71.59 ? 178 PRO B O   1 
ATOM   3126 C CB  . PRO B 2 178 ? 107.084 98.562  146.353 1.00 73.10 ? 178 PRO B CB  1 
ATOM   3127 C CG  . PRO B 2 178 ? 106.950 98.120  147.816 1.00 73.60 ? 178 PRO B CG  1 
ATOM   3128 C CD  . PRO B 2 178 ? 107.533 99.222  148.685 1.00 73.40 ? 178 PRO B CD  1 
ATOM   3129 N N   . GLU B 2 179 ? 105.863 101.166 145.221 1.00 75.48 ? 179 GLU B N   1 
ATOM   3130 C CA  . GLU B 2 179 ? 104.679 101.999 145.103 1.00 77.43 ? 179 GLU B CA  1 
ATOM   3131 C C   . GLU B 2 179 ? 103.526 101.343 145.862 1.00 78.42 ? 179 GLU B C   1 
ATOM   3132 O O   . GLU B 2 179 ? 103.412 100.111 145.865 1.00 74.02 ? 179 GLU B O   1 
ATOM   3133 C CB  . GLU B 2 179 ? 104.301 102.197 143.635 1.00 73.19 ? 179 GLU B CB  1 
ATOM   3134 N N   . PRO B 2 180 ? 102.645 102.122 146.513 1.00 86.93 ? 180 PRO B N   1 
ATOM   3135 C CA  . PRO B 2 180 ? 101.621 101.487 147.353 1.00 85.30 ? 180 PRO B CA  1 
ATOM   3136 C C   . PRO B 2 180 ? 100.560 100.786 146.523 1.00 82.70 ? 180 PRO B C   1 
ATOM   3137 O O   . PRO B 2 180 ? 99.679  101.428 145.943 1.00 82.35 ? 180 PRO B O   1 
ATOM   3138 C CB  . PRO B 2 180 ? 101.040 102.664 148.142 1.00 84.06 ? 180 PRO B CB  1 
ATOM   3139 C CG  . PRO B 2 180 ? 101.199 103.824 147.231 1.00 83.52 ? 180 PRO B CG  1 
ATOM   3140 C CD  . PRO B 2 180 ? 102.470 103.585 146.455 1.00 83.62 ? 180 PRO B CD  1 
ATOM   3141 N N   . GLY B 2 181 ? 100.649 99.460  146.466 1.00 75.95 ? 181 GLY B N   1 
ATOM   3142 C CA  . GLY B 2 181 ? 99.740  98.654  145.676 1.00 76.42 ? 181 GLY B CA  1 
ATOM   3143 C C   . GLY B 2 181 ? 100.314 98.396  144.300 1.00 73.69 ? 181 GLY B C   1 
ATOM   3144 O O   . GLY B 2 181 ? 100.270 99.273  143.432 1.00 73.51 ? 181 GLY B O   1 
ATOM   3145 N N   . GLU B 2 182 ? 100.854 97.200  144.083 1.00 70.36 ? 182 GLU B N   1 
ATOM   3146 C CA  . GLU B 2 182 ? 101.467 96.852  142.808 1.00 70.55 ? 182 GLU B CA  1 
ATOM   3147 C C   . GLU B 2 182 ? 101.819 95.374  142.833 1.00 70.37 ? 182 GLU B C   1 
ATOM   3148 O O   . GLU B 2 182 ? 101.746 94.726  143.881 1.00 68.81 ? 182 GLU B O   1 
ATOM   3149 C CB  . GLU B 2 182 ? 102.728 97.686  142.524 1.00 72.43 ? 182 GLU B CB  1 
ATOM   3150 C CG  . GLU B 2 182 ? 102.958 97.983  141.050 1.00 69.81 ? 182 GLU B CG  1 
ATOM   3151 C CD  . GLU B 2 182 ? 103.990 99.071  140.831 1.00 70.45 ? 182 GLU B CD  1 
ATOM   3152 O OE1 . GLU B 2 182 ? 104.905 99.204  141.671 1.00 67.91 ? 182 GLU B OE1 1 
ATOM   3153 O OE2 . GLU B 2 182 ? 103.887 99.796  139.819 1.00 71.09 ? 182 GLU B OE2 1 
ATOM   3154 N N   . ASP B 2 183 ? 102.199 94.856  141.674 1.00 70.84 ? 183 ASP B N   1 
ATOM   3155 C CA  . ASP B 2 183 ? 102.546 93.447  141.566 1.00 71.34 ? 183 ASP B CA  1 
ATOM   3156 C C   . ASP B 2 183 ? 104.013 93.241  141.953 1.00 70.03 ? 183 ASP B C   1 
ATOM   3157 O O   . ASP B 2 183 ? 104.884 93.970  141.452 1.00 64.91 ? 183 ASP B O   1 
ATOM   3158 C CB  . ASP B 2 183 ? 102.291 92.956  140.146 1.00 70.75 ? 183 ASP B CB  1 
ATOM   3159 C CG  . ASP B 2 183 ? 102.889 91.595  139.887 1.00 69.40 ? 183 ASP B CG  1 
ATOM   3160 O OD1 . ASP B 2 183 ? 104.092 91.536  139.574 1.00 72.02 ? 183 ASP B OD1 1 
ATOM   3161 O OD2 . ASP B 2 183 ? 102.160 90.587  139.996 1.00 66.18 ? 183 ASP B OD2 1 
ATOM   3162 N N   . PRO B 2 184 ? 104.335 92.283  142.838 1.00 73.77 ? 184 PRO B N   1 
ATOM   3163 C CA  . PRO B 2 184 ? 105.755 92.070  143.175 1.00 72.29 ? 184 PRO B CA  1 
ATOM   3164 C C   . PRO B 2 184 ? 106.627 91.693  141.990 1.00 73.13 ? 184 PRO B C   1 
ATOM   3165 O O   . PRO B 2 184 ? 107.791 92.103  141.950 1.00 72.05 ? 184 PRO B O   1 
ATOM   3166 C CB  . PRO B 2 184 ? 105.708 90.939  144.213 1.00 73.62 ? 184 PRO B CB  1 
ATOM   3167 C CG  . PRO B 2 184 ? 104.354 90.989  144.776 1.00 73.82 ? 184 PRO B CG  1 
ATOM   3168 C CD  . PRO B 2 184 ? 103.465 91.416  143.657 1.00 74.76 ? 184 PRO B CD  1 
ATOM   3169 N N   . ARG B 2 185 ? 106.116 90.922  141.027 1.00 72.29 ? 185 ARG B N   1 
ATOM   3170 C CA  . ARG B 2 185 ? 106.936 90.563  139.872 1.00 70.82 ? 185 ARG B CA  1 
ATOM   3171 C C   . ARG B 2 185 ? 107.239 91.791  139.019 1.00 71.11 ? 185 ARG B C   1 
ATOM   3172 O O   . ARG B 2 185 ? 108.365 91.957  138.532 1.00 70.27 ? 185 ARG B O   1 
ATOM   3173 C CB  . ARG B 2 185 ? 106.234 89.480  139.048 1.00 71.65 ? 185 ARG B CB  1 
ATOM   3174 C CG  . ARG B 2 185 ? 107.117 88.781  138.024 1.00 73.21 ? 185 ARG B CG  1 
ATOM   3175 C CD  . ARG B 2 185 ? 106.360 87.751  137.163 1.00 72.61 ? 185 ARG B CD  1 
ATOM   3176 N NE  . ARG B 2 185 ? 105.318 87.011  137.875 1.00 72.42 ? 185 ARG B NE  1 
ATOM   3177 C CZ  . ARG B 2 185 ? 104.041 87.367  137.977 1.00 71.99 ? 185 ARG B CZ  1 
ATOM   3178 N NH1 . ARG B 2 185 ? 103.578 88.481  137.428 1.00 71.54 ? 185 ARG B NH1 1 
ATOM   3179 N NH2 . ARG B 2 185 ? 103.203 86.583  138.649 1.00 72.52 ? 185 ARG B NH2 1 
ATOM   3180 N N   . VAL B 2 186 ? 106.248 92.670  138.841 1.00 72.20 ? 186 VAL B N   1 
ATOM   3181 C CA  . VAL B 2 186 ? 106.466 93.915  138.106 1.00 70.89 ? 186 VAL B CA  1 
ATOM   3182 C C   . VAL B 2 186 ? 107.504 94.771  138.820 1.00 66.61 ? 186 VAL B C   1 
ATOM   3183 O O   . VAL B 2 186 ? 108.403 95.350  138.193 1.00 65.42 ? 186 VAL B O   1 
ATOM   3184 C CB  . VAL B 2 186 ? 105.138 94.679  137.934 1.00 69.85 ? 186 VAL B CB  1 
ATOM   3185 C CG1 . VAL B 2 186 ? 105.388 96.066  137.352 1.00 66.84 ? 186 VAL B CG1 1 
ATOM   3186 C CG2 . VAL B 2 186 ? 104.165 93.909  137.043 1.00 68.97 ? 186 VAL B CG2 1 
ATOM   3187 N N   . THR B 2 187 ? 107.379 94.879  140.145 1.00 64.31 ? 187 THR B N   1 
ATOM   3188 C CA  . THR B 2 187 ? 108.333 95.669  140.916 1.00 65.26 ? 187 THR B CA  1 
ATOM   3189 C C   . THR B 2 187 ? 109.738 95.089  140.802 1.00 63.55 ? 187 THR B C   1 
ATOM   3190 O O   . THR B 2 187 ? 110.715 95.828  140.629 1.00 64.35 ? 187 THR B O   1 
ATOM   3191 C CB  . THR B 2 187 ? 107.885 95.728  142.377 1.00 69.89 ? 187 THR B CB  1 
ATOM   3192 O OG1 . THR B 2 187 ? 106.568 96.289  142.449 1.00 71.00 ? 187 THR B OG1 1 
ATOM   3193 C CG2 . THR B 2 187 ? 108.822 96.588  143.200 1.00 64.71 ? 187 THR B CG2 1 
ATOM   3194 N N   . ARG B 2 188 ? 109.853 93.762  140.884 1.00 67.22 ? 188 ARG B N   1 
ATOM   3195 C CA  . ARG B 2 188 ? 111.145 93.102  140.749 1.00 69.30 ? 188 ARG B CA  1 
ATOM   3196 C C   . ARG B 2 188 ? 111.764 93.394  139.389 1.00 70.56 ? 188 ARG B C   1 
ATOM   3197 O O   . ARG B 2 188 ? 112.942 93.752  139.296 1.00 65.33 ? 188 ARG B O   1 
ATOM   3198 C CB  . ARG B 2 188 ? 110.964 91.595  140.953 1.00 71.88 ? 188 ARG B CB  1 
ATOM   3199 C CG  . ARG B 2 188 ? 112.244 90.784  141.124 1.00 72.35 ? 188 ARG B CG  1 
ATOM   3200 C CD  . ARG B 2 188 ? 111.951 89.304  140.905 1.00 71.67 ? 188 ARG B CD  1 
ATOM   3201 N NE  . ARG B 2 188 ? 113.046 88.431  141.315 1.00 71.26 ? 188 ARG B NE  1 
ATOM   3202 C CZ  . ARG B 2 188 ? 113.190 87.165  140.936 1.00 73.68 ? 188 ARG B CZ  1 
ATOM   3203 N NH1 . ARG B 2 188 ? 112.334 86.582  140.109 1.00 73.40 ? 188 ARG B NH1 1 
ATOM   3204 N NH2 . ARG B 2 188 ? 114.217 86.462  141.403 1.00 72.47 ? 188 ARG B NH2 1 
ATOM   3205 N N   . ALA B 2 189 ? 110.970 93.276  138.321 1.00 69.94 ? 189 ALA B N   1 
ATOM   3206 C CA  . ALA B 2 189 ? 111.501 93.485  136.977 1.00 65.63 ? 189 ALA B CA  1 
ATOM   3207 C C   . ALA B 2 189 ? 111.951 94.927  136.769 1.00 65.32 ? 189 ALA B C   1 
ATOM   3208 O O   . ALA B 2 189 ? 113.049 95.176  136.251 1.00 64.91 ? 189 ALA B O   1 
ATOM   3209 C CB  . ALA B 2 189 ? 110.451 93.102  135.935 1.00 63.01 ? 189 ALA B CB  1 
ATOM   3210 N N   . LYS B 2 190 ? 111.117 95.895  137.160 1.00 62.63 ? 190 LYS B N   1 
ATOM   3211 C CA  . LYS B 2 190 ? 111.473 97.288  136.912 1.00 59.03 ? 190 LYS B CA  1 
ATOM   3212 C C   . LYS B 2 190 ? 112.663 97.715  137.766 1.00 56.90 ? 190 LYS B C   1 
ATOM   3213 O O   . LYS B 2 190 ? 113.550 98.433  137.284 1.00 54.95 ? 190 LYS B O   1 
ATOM   3214 C CB  . LYS B 2 190 ? 110.266 98.199  137.146 1.00 57.86 ? 190 LYS B CB  1 
ATOM   3215 C CG  . LYS B 2 190 ? 109.794 98.289  138.578 1.00 60.64 ? 190 LYS B CG  1 
ATOM   3216 C CD  . LYS B 2 190 ? 108.344 98.761  138.692 1.00 62.90 ? 190 LYS B CD  1 
ATOM   3217 C CE  . LYS B 2 190 ? 108.084 100.103 138.013 1.00 59.28 ? 190 LYS B CE  1 
ATOM   3218 N NZ  . LYS B 2 190 ? 106.663 100.518 138.165 1.00 58.21 ? 190 LYS B NZ  1 
ATOM   3219 N N   . TYR B 2 191 ? 112.722 97.271  139.026 1.00 62.43 ? 191 TYR B N   1 
ATOM   3220 C CA  . TYR B 2 191 ? 113.896 97.572  139.836 1.00 61.28 ? 191 TYR B CA  1 
ATOM   3221 C C   . TYR B 2 191 ? 115.138 96.886  139.288 1.00 62.11 ? 191 TYR B C   1 
ATOM   3222 O O   . TYR B 2 191 ? 116.237 97.438  139.379 1.00 59.44 ? 191 TYR B O   1 
ATOM   3223 C CB  . TYR B 2 191 ? 113.663 97.172  141.292 1.00 63.45 ? 191 TYR B CB  1 
ATOM   3224 C CG  . TYR B 2 191 ? 113.027 98.259  142.130 1.00 61.24 ? 191 TYR B CG  1 
ATOM   3225 C CD1 . TYR B 2 191 ? 113.736 99.405  142.466 1.00 58.18 ? 191 TYR B CD1 1 
ATOM   3226 C CD2 . TYR B 2 191 ? 111.725 98.143  142.582 1.00 61.24 ? 191 TYR B CD2 1 
ATOM   3227 C CE1 . TYR B 2 191 ? 113.165 100.398 143.229 1.00 58.79 ? 191 TYR B CE1 1 
ATOM   3228 C CE2 . TYR B 2 191 ? 111.145 99.134  143.347 1.00 62.89 ? 191 TYR B CE2 1 
ATOM   3229 C CZ  . TYR B 2 191 ? 111.869 100.259 143.667 1.00 62.69 ? 191 TYR B CZ  1 
ATOM   3230 O OH  . TYR B 2 191 ? 111.295 101.250 144.430 1.00 65.48 ? 191 TYR B OH  1 
ATOM   3231 N N   . PHE B 2 192 ? 114.993 95.687  138.718 1.00 62.69 ? 192 PHE B N   1 
ATOM   3232 C CA  . PHE B 2 192 ? 116.146 95.019  138.121 1.00 62.80 ? 192 PHE B CA  1 
ATOM   3233 C C   . PHE B 2 192 ? 116.676 95.828  136.943 1.00 63.25 ? 192 PHE B C   1 
ATOM   3234 O O   . PHE B 2 192 ? 117.890 96.012  136.804 1.00 62.12 ? 192 PHE B O   1 
ATOM   3235 C CB  . PHE B 2 192 ? 115.755 93.599  137.689 1.00 63.06 ? 192 PHE B CB  1 
ATOM   3236 C CG  . PHE B 2 192 ? 116.519 93.069  136.496 1.00 62.04 ? 192 PHE B CG  1 
ATOM   3237 C CD1 . PHE B 2 192 ? 117.904 92.940  136.522 1.00 61.66 ? 192 PHE B CD1 1 
ATOM   3238 C CD2 . PHE B 2 192 ? 115.844 92.701  135.345 1.00 64.29 ? 192 PHE B CD2 1 
ATOM   3239 C CE1 . PHE B 2 192 ? 118.588 92.460  135.429 1.00 64.10 ? 192 PHE B CE1 1 
ATOM   3240 C CE2 . PHE B 2 192 ? 116.528 92.218  134.249 1.00 66.63 ? 192 PHE B CE2 1 
ATOM   3241 C CZ  . PHE B 2 192 ? 117.901 92.098  134.292 1.00 67.80 ? 192 PHE B CZ  1 
ATOM   3242 N N   . ILE B 2 193 ? 115.779 96.316  136.084 1.00 65.55 ? 193 ILE B N   1 
ATOM   3243 C CA  . ILE B 2 193 ? 116.206 97.114  134.934 1.00 60.54 ? 193 ILE B CA  1 
ATOM   3244 C C   . ILE B 2 193 ? 116.893 98.391  135.410 1.00 56.24 ? 193 ILE B C   1 
ATOM   3245 O O   . ILE B 2 193 ? 117.966 98.775  134.914 1.00 49.67 ? 193 ILE B O   1 
ATOM   3246 C CB  . ILE B 2 193 ? 115.001 97.424  134.025 1.00 56.36 ? 193 ILE B CB  1 
ATOM   3247 C CG1 . ILE B 2 193 ? 114.520 96.148  133.324 1.00 55.82 ? 193 ILE B CG1 1 
ATOM   3248 C CG2 . ILE B 2 193 ? 115.361 98.500  132.996 1.00 59.08 ? 193 ILE B CG2 1 
ATOM   3249 C CD1 . ILE B 2 193 ? 113.133 96.253  132.715 1.00 54.78 ? 193 ILE B CD1 1 
ATOM   3250 N N   . ARG B 2 194 ? 116.282 99.066  136.386 1.00 49.03 ? 194 ARG B N   1 
ATOM   3251 C CA  . ARG B 2 194 ? 116.845 100.313 136.888 1.00 46.00 ? 194 ARG B CA  1 
ATOM   3252 C C   . ARG B 2 194 ? 118.205 100.081 137.534 1.00 51.67 ? 194 ARG B C   1 
ATOM   3253 O O   . ARG B 2 194 ? 119.126 100.884 137.356 1.00 55.94 ? 194 ARG B O   1 
ATOM   3254 C CB  . ARG B 2 194 ? 115.874 100.954 137.879 1.00 51.65 ? 194 ARG B CB  1 
ATOM   3255 C CG  . ARG B 2 194 ? 116.312 102.311 138.398 1.00 49.76 ? 194 ARG B CG  1 
ATOM   3256 C CD  . ARG B 2 194 ? 115.202 102.972 139.193 1.00 48.63 ? 194 ARG B CD  1 
ATOM   3257 N NE  . ARG B 2 194 ? 115.739 103.854 140.229 1.00 47.48 ? 194 ARG B NE  1 
ATOM   3258 C CZ  . ARG B 2 194 ? 115.404 103.862 141.516 1.00 49.36 ? 194 ARG B CZ  1 
ATOM   3259 N NH1 . ARG B 2 194 ? 114.474 103.059 142.010 1.00 47.85 ? 194 ARG B NH1 1 
ATOM   3260 N NH2 . ARG B 2 194 ? 116.015 104.713 142.335 1.00 50.20 ? 194 ARG B NH2 1 
ATOM   3261 N N   . LYS B 2 195 ? 118.353 98.986  138.285 1.00 58.58 ? 195 LYS B N   1 
ATOM   3262 C CA  . LYS B 2 195 ? 119.640 98.668  138.891 1.00 57.07 ? 195 LYS B CA  1 
ATOM   3263 C C   . LYS B 2 195 ? 120.675 98.303  137.840 1.00 57.75 ? 195 LYS B C   1 
ATOM   3264 O O   . LYS B 2 195 ? 121.861 98.588  138.019 1.00 51.98 ? 195 LYS B O   1 
ATOM   3265 C CB  . LYS B 2 195 ? 119.481 97.524  139.892 1.00 53.43 ? 195 LYS B CB  1 
ATOM   3266 N N   . GLU B 2 196 ? 120.252 97.669  136.744 1.00 59.40 ? 196 GLU B N   1 
ATOM   3267 C CA  . GLU B 2 196 ? 121.178 97.396  135.651 1.00 57.37 ? 196 GLU B CA  1 
ATOM   3268 C C   . GLU B 2 196 ? 121.715 98.693  135.064 1.00 55.31 ? 196 GLU B C   1 
ATOM   3269 O O   . GLU B 2 196 ? 122.911 98.804  134.768 1.00 53.56 ? 196 GLU B O   1 
ATOM   3270 C CB  . GLU B 2 196 ? 120.485 96.566  134.570 1.00 57.25 ? 196 GLU B CB  1 
ATOM   3271 C CG  . GLU B 2 196 ? 121.428 95.769  133.674 1.00 57.29 ? 196 GLU B CG  1 
ATOM   3272 C CD  . GLU B 2 196 ? 122.121 94.634  134.406 1.00 60.88 ? 196 GLU B CD  1 
ATOM   3273 O OE1 . GLU B 2 196 ? 121.499 93.562  134.568 1.00 59.69 ? 196 GLU B OE1 1 
ATOM   3274 O OE2 . GLU B 2 196 ? 123.286 94.813  134.818 1.00 59.50 ? 196 GLU B OE2 1 
ATOM   3275 N N   . PHE B 2 197 ? 120.842 99.685  134.883 1.00 50.26 ? 197 PHE B N   1 
ATOM   3276 C CA  . PHE B 2 197 ? 121.313 100.991 134.419 1.00 46.87 ? 197 PHE B CA  1 
ATOM   3277 C C   . PHE B 2 197 ? 122.227 101.651 135.451 1.00 49.68 ? 197 PHE B C   1 
ATOM   3278 O O   . PHE B 2 197 ? 123.284 102.199 135.106 1.00 48.78 ? 197 PHE B O   1 
ATOM   3279 C CB  . PHE B 2 197 ? 120.123 101.900 134.110 1.00 46.82 ? 197 PHE B CB  1 
ATOM   3280 C CG  . PHE B 2 197 ? 119.676 101.852 132.676 1.00 45.00 ? 197 PHE B CG  1 
ATOM   3281 C CD1 . PHE B 2 197 ? 120.371 102.531 131.693 1.00 41.62 ? 197 PHE B CD1 1 
ATOM   3282 C CD2 . PHE B 2 197 ? 118.552 101.130 132.316 1.00 47.86 ? 197 PHE B CD2 1 
ATOM   3283 C CE1 . PHE B 2 197 ? 119.954 102.487 130.380 1.00 42.45 ? 197 PHE B CE1 1 
ATOM   3284 C CE2 . PHE B 2 197 ? 118.133 101.082 131.007 1.00 42.09 ? 197 PHE B CE2 1 
ATOM   3285 C CZ  . PHE B 2 197 ? 118.834 101.760 130.038 1.00 44.85 ? 197 PHE B CZ  1 
ATOM   3286 N N   . VAL B 2 198 ? 121.842 101.594 136.728 1.00 54.22 ? 198 VAL B N   1 
ATOM   3287 C CA  . VAL B 2 198 ? 122.588 102.296 137.769 1.00 56.08 ? 198 VAL B CA  1 
ATOM   3288 C C   . VAL B 2 198 ? 123.956 101.659 137.983 1.00 55.91 ? 198 VAL B C   1 
ATOM   3289 O O   . VAL B 2 198 ? 124.906 102.337 138.391 1.00 54.44 ? 198 VAL B O   1 
ATOM   3290 C CB  . VAL B 2 198 ? 121.769 102.339 139.075 1.00 53.97 ? 198 VAL B CB  1 
ATOM   3291 C CG1 . VAL B 2 198 ? 122.635 102.789 140.249 1.00 53.35 ? 198 VAL B CG1 1 
ATOM   3292 C CG2 . VAL B 2 198 ? 120.577 103.272 138.923 1.00 46.85 ? 198 VAL B CG2 1 
ATOM   3293 N N   . ASP B 2 199 ? 124.081 100.353 137.741 1.00 57.48 ? 199 ASP B N   1 
ATOM   3294 C CA  . ASP B 2 199 ? 125.381 99.708  137.879 1.00 60.42 ? 199 ASP B CA  1 
ATOM   3295 C C   . ASP B 2 199 ? 126.385 100.292 136.897 1.00 57.34 ? 199 ASP B C   1 
ATOM   3296 O O   . ASP B 2 199 ? 127.529 100.574 137.264 1.00 55.27 ? 199 ASP B O   1 
ATOM   3297 C CB  . ASP B 2 199 ? 125.245 98.199  137.676 1.00 61.07 ? 199 ASP B CB  1 
ATOM   3298 C CG  . ASP B 2 199 ? 126.371 97.420  138.326 1.00 61.61 ? 199 ASP B CG  1 
ATOM   3299 O OD1 . ASP B 2 199 ? 127.466 97.992  138.494 1.00 63.16 ? 199 ASP B OD1 1 
ATOM   3300 O OD2 . ASP B 2 199 ? 126.160 96.238  138.664 1.00 59.50 ? 199 ASP B OD2 1 
ATOM   3301 N N   . ILE B 2 200 ? 125.972 100.491 135.646 1.00 55.28 ? 200 ILE B N   1 
ATOM   3302 C CA  . ILE B 2 200 ? 126.841 101.145 134.676 1.00 52.96 ? 200 ILE B CA  1 
ATOM   3303 C C   . ILE B 2 200 ? 127.050 102.599 135.058 1.00 48.74 ? 200 ILE B C   1 
ATOM   3304 O O   . ILE B 2 200 ? 128.113 103.179 134.799 1.00 49.25 ? 200 ILE B O   1 
ATOM   3305 C CB  . ILE B 2 200 ? 126.256 101.006 133.262 1.00 53.29 ? 200 ILE B CB  1 
ATOM   3306 C CG1 . ILE B 2 200 ? 126.335 99.540  132.834 1.00 55.41 ? 200 ILE B CG1 1 
ATOM   3307 C CG2 . ILE B 2 200 ? 127.003 101.932 132.282 1.00 50.19 ? 200 ILE B CG2 1 
ATOM   3308 C CD1 . ILE B 2 200 ? 125.571 99.226  131.609 1.00 54.86 ? 200 ILE B CD1 1 
ATOM   3309 N N   . SER B 2 201 ? 126.027 103.224 135.644 1.00 46.26 ? 201 SER B N   1 
ATOM   3310 C CA  . SER B 2 201 ? 126.171 104.615 136.058 1.00 49.39 ? 201 SER B CA  1 
ATOM   3311 C C   . SER B 2 201 ? 127.284 104.767 137.089 1.00 52.98 ? 201 SER B C   1 
ATOM   3312 O O   . SER B 2 201 ? 128.089 105.703 137.011 1.00 54.05 ? 201 SER B O   1 
ATOM   3313 C CB  . SER B 2 201 ? 124.853 105.137 136.625 1.00 49.67 ? 201 SER B CB  1 
ATOM   3314 O OG  . SER B 2 201 ? 125.022 106.409 137.218 1.00 50.68 ? 201 SER B OG  1 
ATOM   3315 N N   . THR B 2 202 ? 127.355 103.843 138.047 1.00 59.37 ? 202 THR B N   1 
ATOM   3316 C CA  . THR B 2 202 ? 128.280 103.931 139.170 1.00 58.94 ? 202 THR B CA  1 
ATOM   3317 C C   . THR B 2 202 ? 129.557 103.115 138.985 1.00 57.75 ? 202 THR B C   1 
ATOM   3318 O O   . THR B 2 202 ? 130.433 103.174 139.852 1.00 56.08 ? 202 THR B O   1 
ATOM   3319 C CB  . THR B 2 202 ? 127.578 103.484 140.459 1.00 58.56 ? 202 THR B CB  1 
ATOM   3320 O OG1 . THR B 2 202 ? 128.364 103.873 141.591 1.00 55.13 ? 202 THR B OG1 1 
ATOM   3321 C CG2 . THR B 2 202 ? 127.381 101.966 140.485 1.00 54.68 ? 202 THR B CG2 1 
ATOM   3322 N N   . ALA B 2 203 ? 129.688 102.357 137.891 1.00 61.99 ? 203 ALA B N   1 
ATOM   3323 C CA  . ALA B 2 203 ? 130.879 101.533 137.697 1.00 61.19 ? 203 ALA B CA  1 
ATOM   3324 C C   . ALA B 2 203 ? 132.136 102.387 137.597 1.00 61.50 ? 203 ALA B C   1 
ATOM   3325 O O   . ALA B 2 203 ? 133.209 101.989 138.066 1.00 63.59 ? 203 ALA B O   1 
ATOM   3326 C CB  . ALA B 2 203 ? 130.716 100.665 136.449 1.00 56.11 ? 203 ALA B CB  1 
ATOM   3327 N N   . SER B 2 204 ? 132.028 103.561 136.972 1.00 57.73 ? 204 SER B N   1 
ATOM   3328 C CA  . SER B 2 204 ? 133.178 104.455 136.886 1.00 60.83 ? 204 SER B CA  1 
ATOM   3329 C C   . SER B 2 204 ? 133.634 104.896 138.272 1.00 62.88 ? 204 SER B C   1 
ATOM   3330 O O   . SER B 2 204 ? 134.837 104.957 138.549 1.00 63.59 ? 204 SER B O   1 
ATOM   3331 C CB  . SER B 2 204 ? 132.835 105.668 136.022 1.00 58.46 ? 204 SER B CB  1 
ATOM   3332 O OG  . SER B 2 204 ? 133.785 106.705 136.198 1.00 59.80 ? 204 SER B OG  1 
ATOM   3333 N N   . GLY B 2 205 ? 132.687 105.205 139.155 1.00 62.17 ? 205 GLY B N   1 
ATOM   3334 C CA  . GLY B 2 205 ? 133.028 105.609 140.509 1.00 61.38 ? 205 GLY B CA  1 
ATOM   3335 C C   . GLY B 2 205 ? 133.797 106.907 140.588 1.00 59.87 ? 205 GLY B C   1 
ATOM   3336 O O   . GLY B 2 205 ? 134.505 107.143 141.573 1.00 56.25 ? 205 GLY B O   1 
ATOM   3337 N N   . ASP B 2 206 ? 133.678 107.763 139.572 1.00 60.86 ? 206 ASP B N   1 
ATOM   3338 C CA  . ASP B 2 206 ? 134.395 109.033 139.583 1.00 59.60 ? 206 ASP B CA  1 
ATOM   3339 C C   . ASP B 2 206 ? 133.754 110.019 140.553 1.00 61.11 ? 206 ASP B C   1 
ATOM   3340 O O   . ASP B 2 206 ? 134.453 110.719 141.296 1.00 60.27 ? 206 ASP B O   1 
ATOM   3341 C CB  . ASP B 2 206 ? 134.437 109.615 138.171 1.00 56.05 ? 206 ASP B CB  1 
ATOM   3342 N N   . GLY B 2 207 ? 132.423 110.094 140.555 1.00 61.07 ? 207 GLY B N   1 
ATOM   3343 C CA  . GLY B 2 207 ? 131.700 111.000 141.422 1.00 59.01 ? 207 GLY B CA  1 
ATOM   3344 C C   . GLY B 2 207 ? 131.567 112.417 140.905 1.00 58.33 ? 207 GLY B C   1 
ATOM   3345 O O   . GLY B 2 207 ? 130.886 113.228 141.545 1.00 55.96 ? 207 GLY B O   1 
ATOM   3346 N N   . ARG B 2 208 ? 132.194 112.742 139.773 1.00 61.69 ? 208 ARG B N   1 
ATOM   3347 C CA  . ARG B 2 208 ? 132.091 114.088 139.218 1.00 59.96 ? 208 ARG B CA  1 
ATOM   3348 C C   . ARG B 2 208 ? 130.661 114.415 138.806 1.00 57.50 ? 208 ARG B C   1 
ATOM   3349 O O   . ARG B 2 208 ? 130.187 115.535 139.027 1.00 56.98 ? 208 ARG B O   1 
ATOM   3350 C CB  . ARG B 2 208 ? 133.036 114.223 138.026 1.00 63.78 ? 208 ARG B CB  1 
ATOM   3351 C CG  . ARG B 2 208 ? 134.477 114.565 138.410 1.00 62.97 ? 208 ARG B CG  1 
ATOM   3352 C CD  . ARG B 2 208 ? 135.362 114.807 137.188 1.00 59.84 ? 208 ARG B CD  1 
ATOM   3353 N NE  . ARG B 2 208 ? 135.145 113.790 136.165 1.00 63.03 ? 208 ARG B NE  1 
ATOM   3354 C CZ  . ARG B 2 208 ? 135.486 112.514 136.291 1.00 62.10 ? 208 ARG B CZ  1 
ATOM   3355 N NH1 . ARG B 2 208 ? 136.166 112.075 137.340 1.00 61.20 ? 208 ARG B NH1 1 
ATOM   3356 N NH2 . ARG B 2 208 ? 135.136 111.652 135.341 1.00 61.82 ? 208 ARG B NH2 1 
ATOM   3357 N N   . HIS B 2 209 ? 129.964 113.452 138.205 1.00 51.60 ? 209 HIS B N   1 
ATOM   3358 C CA  . HIS B 2 209 ? 128.585 113.619 137.769 1.00 49.87 ? 209 HIS B CA  1 
ATOM   3359 C C   . HIS B 2 209 ? 127.828 112.333 138.057 1.00 49.27 ? 209 HIS B C   1 
ATOM   3360 O O   . HIS B 2 209 ? 128.426 111.262 138.187 1.00 57.60 ? 209 HIS B O   1 
ATOM   3361 C CB  . HIS B 2 209 ? 128.499 113.964 136.277 1.00 45.96 ? 209 HIS B CB  1 
ATOM   3362 C CG  . HIS B 2 209 ? 129.390 113.130 135.410 1.00 48.67 ? 209 HIS B CG  1 
ATOM   3363 N ND1 . HIS B 2 209 ? 128.926 112.064 134.672 1.00 48.07 ? 209 HIS B ND1 1 
ATOM   3364 C CD2 . HIS B 2 209 ? 130.718 113.207 135.162 1.00 51.12 ? 209 HIS B CD2 1 
ATOM   3365 C CE1 . HIS B 2 209 ? 129.929 111.519 134.008 1.00 47.66 ? 209 HIS B CE1 1 
ATOM   3366 N NE2 . HIS B 2 209 ? 131.028 112.194 134.288 1.00 50.30 ? 209 HIS B NE2 1 
ATOM   3367 N N   . ILE B 2 210 ? 126.502 112.448 138.152 1.00 33.42 ? 210 ILE B N   1 
ATOM   3368 C CA  . ILE B 2 210 ? 125.642 111.354 138.583 1.00 38.02 ? 210 ILE B CA  1 
ATOM   3369 C C   . ILE B 2 210 ? 124.482 111.224 137.603 1.00 34.80 ? 210 ILE B C   1 
ATOM   3370 O O   . ILE B 2 210 ? 124.323 112.024 136.682 1.00 35.93 ? 210 ILE B O   1 
ATOM   3371 C CB  . ILE B 2 210 ? 125.122 111.552 140.026 1.00 42.25 ? 210 ILE B CB  1 
ATOM   3372 C CG1 . ILE B 2 210 ? 124.561 112.968 140.224 1.00 41.70 ? 210 ILE B CG1 1 
ATOM   3373 C CG2 . ILE B 2 210 ? 126.247 111.292 141.024 1.00 41.09 ? 210 ILE B CG2 1 
ATOM   3374 C CD1 . ILE B 2 210 ? 124.006 113.226 141.613 1.00 41.51 ? 210 ILE B CD1 1 
ATOM   3375 N N   . CYS B 2 211 ? 123.676 110.185 137.813 1.00 36.12 ? 211 CYS B N   1 
ATOM   3376 C CA  . CYS B 2 211 ? 122.526 109.873 136.979 1.00 30.46 ? 211 CYS B CA  1 
ATOM   3377 C C   . CYS B 2 211 ? 121.250 110.005 137.800 1.00 36.35 ? 211 CYS B C   1 
ATOM   3378 O O   . CYS B 2 211 ? 121.244 109.759 139.010 1.00 45.79 ? 211 CYS B O   1 
ATOM   3379 C CB  . CYS B 2 211 ? 122.635 108.458 136.401 1.00 30.37 ? 211 CYS B CB  1 
ATOM   3380 S SG  . CYS B 2 211 ? 121.239 107.956 135.377 1.00 41.43 ? 211 CYS B SG  1 
ATOM   3381 N N   . TYR B 2 212 ? 120.168 110.394 137.126 1.00 32.13 ? 212 TYR B N   1 
ATOM   3382 C CA  . TYR B 2 212 ? 118.871 110.654 137.754 1.00 32.87 ? 212 TYR B CA  1 
ATOM   3383 C C   . TYR B 2 212 ? 117.821 109.771 137.091 1.00 33.58 ? 212 TYR B C   1 
ATOM   3384 O O   . TYR B 2 212 ? 117.165 110.196 136.131 1.00 41.49 ? 212 TYR B O   1 
ATOM   3385 C CB  . TYR B 2 212 ? 118.488 112.127 137.634 1.00 24.53 ? 212 TYR B CB  1 
ATOM   3386 C CG  . TYR B 2 212 ? 119.421 113.066 138.359 1.00 25.55 ? 212 TYR B CG  1 
ATOM   3387 C CD1 . TYR B 2 212 ? 120.601 113.496 137.773 1.00 35.46 ? 212 TYR B CD1 1 
ATOM   3388 C CD2 . TYR B 2 212 ? 119.115 113.531 139.629 1.00 26.93 ? 212 TYR B CD2 1 
ATOM   3389 C CE1 . TYR B 2 212 ? 121.454 114.355 138.433 1.00 30.12 ? 212 TYR B CE1 1 
ATOM   3390 C CE2 . TYR B 2 212 ? 119.961 114.390 140.296 1.00 33.60 ? 212 TYR B CE2 1 
ATOM   3391 C CZ  . TYR B 2 212 ? 121.130 114.798 139.693 1.00 33.21 ? 212 TYR B CZ  1 
ATOM   3392 O OH  . TYR B 2 212 ? 121.978 115.655 140.352 1.00 33.50 ? 212 TYR B OH  1 
ATOM   3393 N N   . PRO B 2 213 ? 117.629 108.538 137.565 1.00 28.13 ? 213 PRO B N   1 
ATOM   3394 C CA  . PRO B 2 213 ? 116.632 107.673 136.927 1.00 32.00 ? 213 PRO B CA  1 
ATOM   3395 C C   . PRO B 2 213 ? 115.213 108.102 137.259 1.00 34.90 ? 213 PRO B C   1 
ATOM   3396 O O   . PRO B 2 213 ? 114.929 108.625 138.339 1.00 42.93 ? 213 PRO B O   1 
ATOM   3397 C CB  . PRO B 2 213 ? 116.941 106.282 137.490 1.00 39.10 ? 213 PRO B CB  1 
ATOM   3398 C CG  . PRO B 2 213 ? 117.852 106.487 138.654 1.00 39.44 ? 213 PRO B CG  1 
ATOM   3399 C CD  . PRO B 2 213 ? 118.153 107.936 138.803 1.00 29.50 ? 213 PRO B CD  1 
ATOM   3400 N N   . HIS B 2 214 ? 114.317 107.874 136.301 1.00 27.59 ? 214 HIS B N   1 
ATOM   3401 C CA  . HIS B 2 214 ? 112.906 108.196 136.457 1.00 29.28 ? 214 HIS B CA  1 
ATOM   3402 C C   . HIS B 2 214 ? 112.086 107.183 135.674 1.00 30.75 ? 214 HIS B C   1 
ATOM   3403 O O   . HIS B 2 214 ? 112.507 106.692 134.625 1.00 35.07 ? 214 HIS B O   1 
ATOM   3404 C CB  . HIS B 2 214 ? 112.592 109.615 135.974 1.00 33.16 ? 214 HIS B CB  1 
ATOM   3405 C CG  . HIS B 2 214 ? 113.113 110.694 136.870 1.00 29.26 ? 214 HIS B CG  1 
ATOM   3406 N ND1 . HIS B 2 214 ? 112.348 111.272 137.859 1.00 31.26 ? 214 HIS B ND1 1 
ATOM   3407 C CD2 . HIS B 2 214 ? 114.316 111.312 136.916 1.00 26.62 ? 214 HIS B CD2 1 
ATOM   3408 C CE1 . HIS B 2 214 ? 113.060 112.194 138.481 1.00 36.44 ? 214 HIS B CE1 1 
ATOM   3409 N NE2 . HIS B 2 214 ? 114.259 112.238 137.928 1.00 28.30 ? 214 HIS B NE2 1 
ATOM   3410 N N   . PHE B 2 215 ? 110.898 106.886 136.193 1.00 34.16 ? 215 PHE B N   1 
ATOM   3411 C CA  . PHE B 2 215 ? 109.940 106.002 135.546 1.00 41.04 ? 215 PHE B CA  1 
ATOM   3412 C C   . PHE B 2 215 ? 108.833 106.845 134.934 1.00 41.10 ? 215 PHE B C   1 
ATOM   3413 O O   . PHE B 2 215 ? 108.251 107.698 135.610 1.00 45.30 ? 215 PHE B O   1 
ATOM   3414 C CB  . PHE B 2 215 ? 109.348 105.000 136.540 1.00 45.94 ? 215 PHE B CB  1 
ATOM   3415 C CG  . PHE B 2 215 ? 110.335 103.983 137.037 1.00 48.90 ? 215 PHE B CG  1 
ATOM   3416 C CD1 . PHE B 2 215 ? 110.815 102.993 136.195 1.00 44.39 ? 215 PHE B CD1 1 
ATOM   3417 C CD2 . PHE B 2 215 ? 110.778 104.011 138.348 1.00 44.44 ? 215 PHE B CD2 1 
ATOM   3418 C CE1 . PHE B 2 215 ? 111.718 102.056 136.650 1.00 44.26 ? 215 PHE B CE1 1 
ATOM   3419 C CE2 . PHE B 2 215 ? 111.682 103.077 138.807 1.00 44.86 ? 215 PHE B CE2 1 
ATOM   3420 C CZ  . PHE B 2 215 ? 112.153 102.098 137.957 1.00 47.05 ? 215 PHE B CZ  1 
ATOM   3421 N N   . THR B 2 216 ? 108.541 106.595 133.658 1.00 39.45 ? 216 THR B N   1 
ATOM   3422 C CA  . THR B 2 216 ? 107.643 107.435 132.879 1.00 42.07 ? 216 THR B CA  1 
ATOM   3423 C C   . THR B 2 216 ? 106.512 106.604 132.300 1.00 41.82 ? 216 THR B C   1 
ATOM   3424 O O   . THR B 2 216 ? 106.735 105.508 131.781 1.00 47.59 ? 216 THR B O   1 
ATOM   3425 C CB  . THR B 2 216 ? 108.390 108.136 131.743 1.00 43.31 ? 216 THR B CB  1 
ATOM   3426 O OG1 . THR B 2 216 ? 109.498 108.862 132.282 1.00 39.72 ? 216 THR B OG1 1 
ATOM   3427 C CG2 . THR B 2 216 ? 107.470 109.092 131.001 1.00 48.45 ? 216 THR B CG2 1 
ATOM   3428 N N   . CYS B 2 217 ? 105.302 107.145 132.383 1.00 52.45 ? 217 CYS B N   1 
ATOM   3429 C CA  . CYS B 2 217 ? 104.114 106.537 131.815 1.00 57.53 ? 217 CYS B CA  1 
ATOM   3430 C C   . CYS B 2 217 ? 103.933 107.021 130.378 1.00 58.37 ? 217 CYS B C   1 
ATOM   3431 O O   . CYS B 2 217 ? 104.502 108.030 129.958 1.00 55.56 ? 217 CYS B O   1 
ATOM   3432 C CB  . CYS B 2 217 ? 102.894 106.874 132.676 1.00 61.66 ? 217 CYS B CB  1 
ATOM   3433 S SG  . CYS B 2 217 ? 101.390 105.976 132.254 1.00 64.68 ? 217 CYS B SG  1 
ATOM   3434 N N   . ALA B 2 218 ? 103.132 106.280 129.610 1.00 67.43 ? 218 ALA B N   1 
ATOM   3435 C CA  . ALA B 2 218 ? 102.843 106.699 128.242 1.00 71.03 ? 218 ALA B CA  1 
ATOM   3436 C C   . ALA B 2 218 ? 102.100 108.029 128.223 1.00 68.93 ? 218 ALA B C   1 
ATOM   3437 O O   . ALA B 2 218 ? 102.424 108.915 127.423 1.00 61.62 ? 218 ALA B O   1 
ATOM   3438 C CB  . ALA B 2 218 ? 102.033 105.620 127.523 1.00 68.36 ? 218 ALA B CB  1 
ATOM   3439 N N   . VAL B 2 219 ? 101.111 108.183 129.096 1.00 69.04 ? 219 VAL B N   1 
ATOM   3440 C CA  . VAL B 2 219 ? 100.374 109.434 129.269 1.00 67.47 ? 219 VAL B CA  1 
ATOM   3441 C C   . VAL B 2 219 ? 100.748 109.938 130.657 1.00 64.32 ? 219 VAL B C   1 
ATOM   3442 O O   . VAL B 2 219 ? 100.293 109.410 131.676 1.00 64.97 ? 219 VAL B O   1 
ATOM   3443 C CB  . VAL B 2 219 ? 98.860  109.246 129.109 1.00 67.49 ? 219 VAL B CB  1 
ATOM   3444 C CG1 . VAL B 2 219 ? 98.054  110.285 129.910 1.00 65.54 ? 219 VAL B CG1 1 
ATOM   3445 C CG2 . VAL B 2 219 ? 98.478  109.300 127.638 1.00 66.61 ? 219 VAL B CG2 1 
ATOM   3446 N N   . ASP B 2 220 ? 101.606 110.956 130.703 1.00 59.87 ? 220 ASP B N   1 
ATOM   3447 C CA  . ASP B 2 220 ? 102.052 111.569 131.949 1.00 62.02 ? 220 ASP B CA  1 
ATOM   3448 C C   . ASP B 2 220 ? 101.973 113.077 131.786 1.00 60.49 ? 220 ASP B C   1 
ATOM   3449 O O   . ASP B 2 220 ? 102.736 113.661 131.009 1.00 60.53 ? 220 ASP B O   1 
ATOM   3450 C CB  . ASP B 2 220 ? 103.477 111.133 132.302 1.00 60.95 ? 220 ASP B CB  1 
ATOM   3451 C CG  . ASP B 2 220 ? 103.801 111.331 133.769 1.00 59.86 ? 220 ASP B CG  1 
ATOM   3452 O OD1 . ASP B 2 220 ? 103.101 112.123 134.433 1.00 56.96 ? 220 ASP B OD1 1 
ATOM   3453 O OD2 . ASP B 2 220 ? 104.755 110.691 134.259 1.00 59.43 ? 220 ASP B OD2 1 
ATOM   3454 N N   . THR B 2 221 ? 101.052 113.704 132.517 1.00 57.72 ? 221 THR B N   1 
ATOM   3455 C CA  . THR B 2 221 ? 100.836 115.138 132.365 1.00 58.36 ? 221 THR B CA  1 
ATOM   3456 C C   . THR B 2 221 ? 102.048 115.950 132.798 1.00 58.44 ? 221 THR B C   1 
ATOM   3457 O O   . THR B 2 221 ? 102.393 116.933 132.133 1.00 59.58 ? 221 THR B O   1 
ATOM   3458 C CB  . THR B 2 221 ? 99.606  115.582 133.163 1.00 59.98 ? 221 THR B CB  1 
ATOM   3459 O OG1 . THR B 2 221 ? 99.880  115.492 134.566 1.00 58.37 ? 221 THR B OG1 1 
ATOM   3460 C CG2 . THR B 2 221 ? 98.389  114.728 132.818 1.00 58.50 ? 221 THR B CG2 1 
ATOM   3461 N N   . GLU B 2 222 ? 102.710 115.552 133.886 1.00 54.00 ? 222 GLU B N   1 
ATOM   3462 C CA  . GLU B 2 222 ? 103.807 116.318 134.474 1.00 51.99 ? 222 GLU B CA  1 
ATOM   3463 C C   . GLU B 2 222 ? 105.125 115.598 134.201 1.00 50.51 ? 222 GLU B C   1 
ATOM   3464 O O   . GLU B 2 222 ? 105.339 114.473 134.660 1.00 52.25 ? 222 GLU B O   1 
ATOM   3465 C CB  . GLU B 2 222 ? 103.587 116.558 135.973 1.00 52.29 ? 222 GLU B CB  1 
ATOM   3466 C CG  . GLU B 2 222 ? 103.068 115.383 136.841 1.00 57.71 ? 222 GLU B CG  1 
ATOM   3467 C CD  . GLU B 2 222 ? 104.143 114.407 137.282 1.00 54.95 ? 222 GLU B CD  1 
ATOM   3468 O OE1 . GLU B 2 222 ? 103.795 113.250 137.595 1.00 52.89 ? 222 GLU B OE1 1 
ATOM   3469 O OE2 . GLU B 2 222 ? 105.331 114.789 137.325 1.00 51.25 ? 222 GLU B OE2 1 
ATOM   3470 N N   . ASN B 2 223 ? 105.983 116.238 133.407 1.00 45.79 ? 223 ASN B N   1 
ATOM   3471 C CA  . ASN B 2 223 ? 107.365 115.810 133.230 1.00 42.89 ? 223 ASN B CA  1 
ATOM   3472 C C   . ASN B 2 223 ? 108.357 116.957 133.306 1.00 40.07 ? 223 ASN B C   1 
ATOM   3473 O O   . ASN B 2 223 ? 109.538 116.702 133.555 1.00 41.36 ? 223 ASN B O   1 
ATOM   3474 C CB  . ASN B 2 223 ? 107.541 115.092 131.883 1.00 47.35 ? 223 ASN B CB  1 
ATOM   3475 C CG  . ASN B 2 223 ? 107.715 113.589 132.031 1.00 48.32 ? 223 ASN B CG  1 
ATOM   3476 O OD1 . ASN B 2 223 ? 108.407 113.113 132.930 1.00 46.42 ? 223 ASN B OD1 1 
ATOM   3477 N ND2 . ASN B 2 223 ? 107.086 112.834 131.138 1.00 44.35 ? 223 ASN B ND2 1 
ATOM   3478 N N   . ALA B 2 224 ? 107.929 118.205 133.103 1.00 40.66 ? 224 ALA B N   1 
ATOM   3479 C CA  . ALA B 2 224 ? 108.828 119.341 133.241 1.00 44.67 ? 224 ALA B CA  1 
ATOM   3480 C C   . ALA B 2 224 ? 109.209 119.590 134.692 1.00 46.29 ? 224 ALA B C   1 
ATOM   3481 O O   . ALA B 2 224 ? 110.313 120.072 134.962 1.00 46.75 ? 224 ALA B O   1 
ATOM   3482 C CB  . ALA B 2 224 ? 108.183 120.595 132.653 1.00 49.04 ? 224 ALA B CB  1 
ATOM   3483 N N   . ARG B 2 225 ? 108.313 119.281 135.633 1.00 45.67 ? 225 ARG B N   1 
ATOM   3484 C CA  . ARG B 2 225 ? 108.641 119.446 137.045 1.00 41.52 ? 225 ARG B CA  1 
ATOM   3485 C C   . ARG B 2 225 ? 109.796 118.541 137.448 1.00 41.58 ? 225 ARG B C   1 
ATOM   3486 O O   . ARG B 2 225 ? 110.666 118.944 138.228 1.00 43.77 ? 225 ARG B O   1 
ATOM   3487 C CB  . ARG B 2 225 ? 107.408 119.162 137.906 1.00 40.33 ? 225 ARG B CB  1 
ATOM   3488 C CG  . ARG B 2 225 ? 107.558 119.370 139.427 1.00 40.45 ? 225 ARG B CG  1 
ATOM   3489 C CD  . ARG B 2 225 ? 108.331 120.623 139.850 1.00 44.35 ? 225 ARG B CD  1 
ATOM   3490 N NE  . ARG B 2 225 ? 107.592 121.849 139.569 1.00 43.65 ? 225 ARG B NE  1 
ATOM   3491 C CZ  . ARG B 2 225 ? 107.939 123.057 139.995 1.00 43.13 ? 225 ARG B CZ  1 
ATOM   3492 N NH1 . ARG B 2 225 ? 109.020 123.253 140.734 1.00 41.43 ? 225 ARG B NH1 1 
ATOM   3493 N NH2 . ARG B 2 225 ? 107.178 124.099 139.672 1.00 43.48 ? 225 ARG B NH2 1 
ATOM   3494 N N   . ARG B 2 226 ? 109.818 117.311 136.931 1.00 35.37 ? 226 ARG B N   1 
ATOM   3495 C CA  . ARG B 2 226 ? 110.923 116.407 137.226 1.00 36.31 ? 226 ARG B CA  1 
ATOM   3496 C C   . ARG B 2 226 ? 112.244 116.978 136.726 1.00 44.17 ? 226 ARG B C   1 
ATOM   3497 O O   . ARG B 2 226 ? 113.240 116.999 137.461 1.00 49.54 ? 226 ARG B O   1 
ATOM   3498 C CB  . ARG B 2 226 ? 110.660 115.043 136.592 1.00 34.81 ? 226 ARG B CB  1 
ATOM   3499 C CG  . ARG B 2 226 ? 109.356 114.397 137.028 1.00 42.21 ? 226 ARG B CG  1 
ATOM   3500 C CD  . ARG B 2 226 ? 109.306 112.928 136.639 1.00 45.58 ? 226 ARG B CD  1 
ATOM   3501 N NE  . ARG B 2 226 ? 108.045 112.300 137.019 1.00 46.20 ? 226 ARG B NE  1 
ATOM   3502 C CZ  . ARG B 2 226 ? 107.811 110.994 137.000 1.00 43.31 ? 226 ARG B CZ  1 
ATOM   3503 N NH1 . ARG B 2 226 ? 108.737 110.125 136.623 1.00 46.91 ? 226 ARG B NH1 1 
ATOM   3504 N NH2 . ARG B 2 226 ? 106.615 110.544 137.369 1.00 38.08 ? 226 ARG B NH2 1 
ATOM   3505 N N   . ILE B 2 227 ? 112.265 117.465 135.484 1.00 40.02 ? 227 ILE B N   1 
ATOM   3506 C CA  . ILE B 2 227 ? 113.489 118.036 134.932 1.00 32.43 ? 227 ILE B CA  1 
ATOM   3507 C C   . ILE B 2 227 ? 113.900 119.268 135.723 1.00 34.62 ? 227 ILE B C   1 
ATOM   3508 O O   . ILE B 2 227 ? 115.091 119.519 135.927 1.00 40.83 ? 227 ILE B O   1 
ATOM   3509 C CB  . ILE B 2 227 ? 113.311 118.358 133.436 1.00 30.60 ? 227 ILE B CB  1 
ATOM   3510 C CG1 . ILE B 2 227 ? 113.056 117.069 132.638 1.00 35.75 ? 227 ILE B CG1 1 
ATOM   3511 C CG2 . ILE B 2 227 ? 114.544 119.113 132.925 1.00 32.91 ? 227 ILE B CG2 1 
ATOM   3512 C CD1 . ILE B 2 227 ? 112.660 117.282 131.185 1.00 36.91 ? 227 ILE B CD1 1 
ATOM   3513 N N   . PHE B 2 228 ? 112.926 120.058 136.178 1.00 39.21 ? 228 PHE B N   1 
ATOM   3514 C CA  . PHE B 2 228 ? 113.246 121.237 136.973 1.00 42.37 ? 228 PHE B CA  1 
ATOM   3515 C C   . PHE B 2 228 ? 113.891 120.843 138.296 1.00 37.39 ? 228 PHE B C   1 
ATOM   3516 O O   . PHE B 2 228 ? 114.895 121.434 138.708 1.00 40.55 ? 228 PHE B O   1 
ATOM   3517 C CB  . PHE B 2 228 ? 111.975 122.063 137.210 1.00 45.00 ? 228 PHE B CB  1 
ATOM   3518 C CG  . PHE B 2 228 ? 112.200 123.410 137.878 1.00 42.64 ? 228 PHE B CG  1 
ATOM   3519 C CD1 . PHE B 2 228 ? 113.437 124.045 137.877 1.00 42.62 ? 228 PHE B CD1 1 
ATOM   3520 C CD2 . PHE B 2 228 ? 111.139 124.053 138.489 1.00 43.41 ? 228 PHE B CD2 1 
ATOM   3521 C CE1 . PHE B 2 228 ? 113.605 125.269 138.488 1.00 44.91 ? 228 PHE B CE1 1 
ATOM   3522 C CE2 . PHE B 2 228 ? 111.308 125.277 139.102 1.00 43.44 ? 228 PHE B CE2 1 
ATOM   3523 C CZ  . PHE B 2 228 ? 112.539 125.886 139.098 1.00 45.43 ? 228 PHE B CZ  1 
ATOM   3524 N N   . ASN B 2 229 ? 113.333 119.843 138.974 1.00 31.62 ? 229 ASN B N   1 
ATOM   3525 C CA  . ASN B 2 229 ? 113.859 119.421 140.265 1.00 37.05 ? 229 ASN B CA  1 
ATOM   3526 C C   . ASN B 2 229 ? 115.186 118.684 140.155 1.00 37.11 ? 229 ASN B C   1 
ATOM   3527 O O   . ASN B 2 229 ? 115.911 118.614 141.152 1.00 44.27 ? 229 ASN B O   1 
ATOM   3528 C CB  . ASN B 2 229 ? 112.843 118.544 141.000 1.00 35.13 ? 229 ASN B CB  1 
ATOM   3529 C CG  . ASN B 2 229 ? 111.470 119.174 141.065 1.00 35.73 ? 229 ASN B CG  1 
ATOM   3530 O OD1 . ASN B 2 229 ? 111.323 120.385 140.907 1.00 38.91 ? 229 ASN B OD1 1 
ATOM   3531 N ND2 . ASN B 2 229 ? 110.453 118.356 141.306 1.00 33.80 ? 229 ASN B ND2 1 
ATOM   3532 N N   . ASP B 2 230 ? 115.522 118.133 138.990 1.00 28.41 ? 230 ASP B N   1 
ATOM   3533 C CA  . ASP B 2 230 ? 116.864 117.596 138.768 1.00 28.14 ? 230 ASP B CA  1 
ATOM   3534 C C   . ASP B 2 230 ? 117.872 118.652 138.343 1.00 35.89 ? 230 ASP B C   1 
ATOM   3535 O O   . ASP B 2 230 ? 119.033 118.587 138.750 1.00 37.33 ? 230 ASP B O   1 
ATOM   3536 C CB  . ASP B 2 230 ? 116.839 116.477 137.723 1.00 33.05 ? 230 ASP B CB  1 
ATOM   3537 C CG  . ASP B 2 230 ? 115.673 115.535 137.908 1.00 42.31 ? 230 ASP B CG  1 
ATOM   3538 O OD1 . ASP B 2 230 ? 115.341 115.225 139.071 1.00 42.91 ? 230 ASP B OD1 1 
ATOM   3539 O OD2 . ASP B 2 230 ? 115.076 115.116 136.895 1.00 38.21 ? 230 ASP B OD2 1 
ATOM   3540 N N   . CYS B 2 231 ? 117.462 119.644 137.550 1.00 37.06 ? 231 CYS B N   1 
ATOM   3541 C CA  . CYS B 2 231 ? 118.379 120.718 137.184 1.00 33.87 ? 231 CYS B CA  1 
ATOM   3542 C C   . CYS B 2 231 ? 118.698 121.602 138.382 1.00 42.51 ? 231 CYS B C   1 
ATOM   3543 O O   . CYS B 2 231 ? 119.826 122.093 138.518 1.00 46.80 ? 231 CYS B O   1 
ATOM   3544 C CB  . CYS B 2 231 ? 117.789 121.543 136.045 1.00 29.21 ? 231 CYS B CB  1 
ATOM   3545 S SG  . CYS B 2 231 ? 117.796 120.691 134.456 1.00 39.93 ? 231 CYS B SG  1 
ATOM   3546 N N   . LYS B 2 232 ? 117.718 121.819 139.264 1.00 39.32 ? 232 LYS B N   1 
ATOM   3547 C CA  . LYS B 2 232 ? 117.993 122.547 140.497 1.00 30.66 ? 232 LYS B CA  1 
ATOM   3548 C C   . LYS B 2 232 ? 119.021 121.805 141.338 1.00 32.37 ? 232 LYS B C   1 
ATOM   3549 O O   . LYS B 2 232 ? 119.942 122.418 141.886 1.00 36.54 ? 232 LYS B O   1 
ATOM   3550 C CB  . LYS B 2 232 ? 116.696 122.757 141.280 1.00 33.00 ? 232 LYS B CB  1 
ATOM   3551 C CG  . LYS B 2 232 ? 116.844 123.578 142.568 1.00 32.16 ? 232 LYS B CG  1 
ATOM   3552 C CD  . LYS B 2 232 ? 115.554 123.674 143.392 1.00 37.50 ? 232 LYS B CD  1 
ATOM   3553 C CE  . LYS B 2 232 ? 114.366 124.258 142.631 1.00 37.98 ? 232 LYS B CE  1 
ATOM   3554 N NZ  . LYS B 2 232 ? 113.138 124.256 143.471 1.00 40.79 ? 232 LYS B NZ  1 
ATOM   3555 N N   . ASP B 2 233 ? 118.885 120.481 141.443 1.00 29.33 ? 233 ASP B N   1 
ATOM   3556 C CA  . ASP B 2 233 ? 119.870 119.689 142.171 1.00 29.18 ? 233 ASP B CA  1 
ATOM   3557 C C   . ASP B 2 233 ? 121.238 119.771 141.508 1.00 32.27 ? 233 ASP B C   1 
ATOM   3558 O O   . ASP B 2 233 ? 122.261 119.847 142.196 1.00 43.10 ? 233 ASP B O   1 
ATOM   3559 C CB  . ASP B 2 233 ? 119.405 118.236 142.262 1.00 32.96 ? 233 ASP B CB  1 
ATOM   3560 C CG  . ASP B 2 233 ? 120.150 117.445 143.322 1.00 38.55 ? 233 ASP B CG  1 
ATOM   3561 O OD1 . ASP B 2 233 ? 121.244 117.873 143.744 1.00 35.00 ? 233 ASP B OD1 1 
ATOM   3562 O OD2 . ASP B 2 233 ? 119.637 116.384 143.735 1.00 43.09 ? 233 ASP B OD2 1 
ATOM   3563 N N   . ILE B 2 234 ? 121.274 119.751 140.175 1.00 24.61 ? 234 ILE B N   1 
ATOM   3564 C CA  . ILE B 2 234 ? 122.546 119.827 139.458 1.00 29.39 ? 234 ILE B CA  1 
ATOM   3565 C C   . ILE B 2 234 ? 123.244 121.145 139.765 1.00 34.33 ? 234 ILE B C   1 
ATOM   3566 O O   . ILE B 2 234 ? 124.442 121.183 140.074 1.00 34.72 ? 234 ILE B O   1 
ATOM   3567 C CB  . ILE B 2 234 ? 122.308 119.652 137.947 1.00 29.37 ? 234 ILE B CB  1 
ATOM   3568 C CG1 . ILE B 2 234 ? 122.040 118.181 137.631 1.00 37.88 ? 234 ILE B CG1 1 
ATOM   3569 C CG2 . ILE B 2 234 ? 123.513 120.144 137.136 1.00 30.28 ? 234 ILE B CG2 1 
ATOM   3570 C CD1 . ILE B 2 234 ? 121.368 117.953 136.300 1.00 32.77 ? 234 ILE B CD1 1 
ATOM   3571 N N   . ILE B 2 235 ? 122.499 122.248 139.690 1.00 35.40 ? 235 ILE B N   1 
ATOM   3572 C CA  . ILE B 2 235 ? 123.094 123.559 139.924 1.00 33.05 ? 235 ILE B CA  1 
ATOM   3573 C C   . ILE B 2 235 ? 123.496 123.709 141.386 1.00 35.56 ? 235 ILE B C   1 
ATOM   3574 O O   . ILE B 2 235 ? 124.529 124.312 141.698 1.00 37.04 ? 235 ILE B O   1 
ATOM   3575 C CB  . ILE B 2 235 ? 122.129 124.672 139.474 1.00 29.75 ? 235 ILE B CB  1 
ATOM   3576 C CG1 . ILE B 2 235 ? 121.905 124.585 137.956 1.00 26.84 ? 235 ILE B CG1 1 
ATOM   3577 C CG2 . ILE B 2 235 ? 122.680 126.039 139.899 1.00 41.74 ? 235 ILE B CG2 1 
ATOM   3578 C CD1 . ILE B 2 235 ? 120.851 125.521 137.408 1.00 31.23 ? 235 ILE B CD1 1 
ATOM   3579 N N   . LEU B 2 236 ? 122.694 123.167 142.305 1.00 31.08 ? 236 LEU B N   1 
ATOM   3580 C CA  . LEU B 2 236 ? 123.052 123.214 143.717 1.00 28.50 ? 236 LEU B CA  1 
ATOM   3581 C C   . LEU B 2 236 ? 124.340 122.447 143.978 1.00 36.62 ? 236 LEU B C   1 
ATOM   3582 O O   . LEU B 2 236 ? 125.197 122.901 144.743 1.00 43.44 ? 236 LEU B O   1 
ATOM   3583 C CB  . LEU B 2 236 ? 121.912 122.651 144.563 1.00 31.19 ? 236 LEU B CB  1 
ATOM   3584 C CG  . LEU B 2 236 ? 122.090 122.721 146.081 1.00 33.94 ? 236 LEU B CG  1 
ATOM   3585 C CD1 . LEU B 2 236 ? 120.802 123.183 146.740 1.00 38.37 ? 236 LEU B CD1 1 
ATOM   3586 C CD2 . LEU B 2 236 ? 122.522 121.380 146.648 1.00 38.10 ? 236 LEU B CD2 1 
ATOM   3587 N N   . GLN B 2 237 ? 124.493 121.278 143.352 1.00 30.72 ? 237 GLN B N   1 
ATOM   3588 C CA  . GLN B 2 237 ? 125.719 120.508 143.522 1.00 35.08 ? 237 GLN B CA  1 
ATOM   3589 C C   . GLN B 2 237 ? 126.913 121.244 142.933 1.00 40.17 ? 237 GLN B C   1 
ATOM   3590 O O   . GLN B 2 237 ? 128.008 121.228 143.508 1.00 42.00 ? 237 GLN B O   1 
ATOM   3591 C CB  . GLN B 2 237 ? 125.566 119.130 142.881 1.00 33.12 ? 237 GLN B CB  1 
ATOM   3592 C CG  . GLN B 2 237 ? 124.642 118.192 143.640 1.00 38.42 ? 237 GLN B CG  1 
ATOM   3593 C CD  . GLN B 2 237 ? 125.209 117.764 144.978 1.00 37.83 ? 237 GLN B CD  1 
ATOM   3594 O OE1 . GLN B 2 237 ? 126.414 117.554 145.116 1.00 36.74 ? 237 GLN B OE1 1 
ATOM   3595 N NE2 . GLN B 2 237 ? 124.341 117.634 145.973 1.00 35.67 ? 237 GLN B NE2 1 
ATOM   3596 N N   . MET B 2 238 ? 126.724 121.897 141.784 1.00 38.31 ? 238 MET B N   1 
ATOM   3597 C CA  . MET B 2 238 ? 127.812 122.681 141.206 1.00 36.95 ? 238 MET B CA  1 
ATOM   3598 C C   . MET B 2 238 ? 128.219 123.820 142.132 1.00 38.49 ? 238 MET B C   1 
ATOM   3599 O O   . MET B 2 238 ? 129.413 124.080 142.321 1.00 42.06 ? 238 MET B O   1 
ATOM   3600 C CB  . MET B 2 238 ? 127.404 123.228 139.839 1.00 37.90 ? 238 MET B CB  1 
ATOM   3601 C CG  . MET B 2 238 ? 127.596 122.235 138.699 1.00 39.65 ? 238 MET B CG  1 
ATOM   3602 S SD  . MET B 2 238 ? 126.878 122.709 137.105 1.00 47.73 ? 238 MET B SD  1 
ATOM   3603 C CE  . MET B 2 238 ? 126.701 124.488 137.247 1.00 35.94 ? 238 MET B CE  1 
ATOM   3604 N N   . ASN B 2 239 ? 127.238 124.512 142.717 1.00 38.84 ? 239 ASN B N   1 
ATOM   3605 C CA  . ASN B 2 239 ? 127.549 125.594 143.645 1.00 35.75 ? 239 ASN B CA  1 
ATOM   3606 C C   . ASN B 2 239 ? 128.268 125.068 144.881 1.00 36.65 ? 239 ASN B C   1 
ATOM   3607 O O   . ASN B 2 239 ? 129.233 125.682 145.354 1.00 42.86 ? 239 ASN B O   1 
ATOM   3608 C CB  . ASN B 2 239 ? 126.269 126.330 144.041 1.00 35.42 ? 239 ASN B CB  1 
ATOM   3609 C CG  . ASN B 2 239 ? 125.653 127.090 142.883 1.00 36.05 ? 239 ASN B CG  1 
ATOM   3610 O OD1 . ASN B 2 239 ? 126.262 127.230 141.824 1.00 36.50 ? 239 ASN B OD1 1 
ATOM   3611 N ND2 . ASN B 2 239 ? 124.439 127.588 143.080 1.00 38.82 ? 239 ASN B ND2 1 
ATOM   3612 N N   . LEU B 2 240 ? 127.817 123.929 145.415 1.00 32.53 ? 240 LEU B N   1 
ATOM   3613 C CA  . LEU B 2 240 ? 128.487 123.334 146.569 1.00 36.85 ? 240 LEU B CA  1 
ATOM   3614 C C   . LEU B 2 240 ? 129.931 122.988 146.241 1.00 39.42 ? 240 LEU B C   1 
ATOM   3615 O O   . LEU B 2 240 ? 130.834 123.216 147.055 1.00 45.62 ? 240 LEU B O   1 
ATOM   3616 C CB  . LEU B 2 240 ? 127.748 122.077 147.032 1.00 32.92 ? 240 LEU B CB  1 
ATOM   3617 C CG  . LEU B 2 240 ? 126.788 122.208 148.214 1.00 34.39 ? 240 LEU B CG  1 
ATOM   3618 C CD1 . LEU B 2 240 ? 125.624 123.137 147.901 1.00 34.61 ? 240 LEU B CD1 1 
ATOM   3619 C CD2 . LEU B 2 240 ? 126.282 120.836 148.628 1.00 36.27 ? 240 LEU B CD2 1 
ATOM   3620 N N   . ARG B 2 241 ? 130.169 122.429 145.055 1.00 42.23 ? 241 ARG B N   1 
ATOM   3621 C CA  . ARG B 2 241 ? 131.529 122.075 144.668 1.00 45.37 ? 241 ARG B CA  1 
ATOM   3622 C C   . ARG B 2 241 ? 132.396 123.316 144.498 1.00 40.64 ? 241 ARG B C   1 
ATOM   3623 O O   . ARG B 2 241 ? 133.557 123.330 144.924 1.00 41.01 ? 241 ARG B O   1 
ATOM   3624 C CB  . ARG B 2 241 ? 131.499 121.249 143.381 1.00 48.27 ? 241 ARG B CB  1 
ATOM   3625 C CG  . ARG B 2 241 ? 132.842 121.104 142.680 1.00 46.31 ? 241 ARG B CG  1 
ATOM   3626 C CD  . ARG B 2 241 ? 132.830 119.987 141.641 1.00 45.30 ? 241 ARG B CD  1 
ATOM   3627 N NE  . ARG B 2 241 ? 131.604 119.963 140.845 1.00 43.89 ? 241 ARG B NE  1 
ATOM   3628 C CZ  . ARG B 2 241 ? 130.553 119.176 141.052 1.00 45.44 ? 241 ARG B CZ  1 
ATOM   3629 N NH1 . ARG B 2 241 ? 130.505 118.316 142.059 1.00 44.38 ? 241 ARG B NH1 1 
ATOM   3630 N NH2 . ARG B 2 241 ? 129.514 119.256 140.226 1.00 45.70 ? 241 ARG B NH2 1 
ATOM   3631 N N   . GLU B 2 242 ? 131.856 124.367 143.881 1.00 40.02 ? 242 GLU B N   1 
ATOM   3632 C CA  . GLU B 2 242 ? 132.637 125.562 143.590 1.00 40.84 ? 242 GLU B CA  1 
ATOM   3633 C C   . GLU B 2 242 ? 132.860 126.445 144.811 1.00 42.75 ? 242 GLU B C   1 
ATOM   3634 O O   . GLU B 2 242 ? 133.787 127.262 144.797 1.00 46.76 ? 242 GLU B O   1 
ATOM   3635 C CB  . GLU B 2 242 ? 131.961 126.371 142.470 1.00 43.18 ? 242 GLU B CB  1 
ATOM   3636 C CG  . GLU B 2 242 ? 131.100 127.560 142.914 1.00 43.23 ? 242 GLU B CG  1 
ATOM   3637 C CD  . GLU B 2 242 ? 130.286 128.146 141.777 1.00 48.00 ? 242 GLU B CD  1 
ATOM   3638 O OE1 . GLU B 2 242 ? 130.332 127.594 140.658 1.00 45.82 ? 242 GLU B OE1 1 
ATOM   3639 O OE2 . GLU B 2 242 ? 129.599 129.163 142.003 1.00 49.16 ? 242 GLU B OE2 1 
ATOM   3640 N N   . TYR B 2 243 ? 132.043 126.313 145.855 1.00 42.56 ? 243 TYR B N   1 
ATOM   3641 C CA  . TYR B 2 243 ? 132.214 127.091 147.075 1.00 37.89 ? 243 TYR B CA  1 
ATOM   3642 C C   . TYR B 2 243 ? 133.156 126.422 148.075 1.00 39.39 ? 243 TYR B C   1 
ATOM   3643 O O   . TYR B 2 243 ? 133.274 126.896 149.209 1.00 47.04 ? 243 TYR B O   1 
ATOM   3644 C CB  . TYR B 2 243 ? 130.851 127.354 147.725 1.00 38.95 ? 243 TYR B CB  1 
ATOM   3645 C CG  . TYR B 2 243 ? 130.325 128.745 147.464 1.00 39.00 ? 243 TYR B CG  1 
ATOM   3646 C CD1 . TYR B 2 243 ? 130.769 129.826 148.212 1.00 43.43 ? 243 TYR B CD1 1 
ATOM   3647 C CD2 . TYR B 2 243 ? 129.389 128.979 146.468 1.00 38.55 ? 243 TYR B CD2 1 
ATOM   3648 C CE1 . TYR B 2 243 ? 130.294 131.100 147.976 1.00 41.99 ? 243 TYR B CE1 1 
ATOM   3649 C CE2 . TYR B 2 243 ? 128.908 130.250 146.225 1.00 41.03 ? 243 TYR B CE2 1 
ATOM   3650 C CZ  . TYR B 2 243 ? 129.364 131.306 146.982 1.00 41.43 ? 243 TYR B CZ  1 
ATOM   3651 O OH  . TYR B 2 243 ? 128.890 132.576 146.747 1.00 40.09 ? 243 TYR B OH  1 
ATOM   3652 N N   . ASN B 2 244 ? 133.836 125.344 147.678 1.00 39.55 ? 244 ASN B N   1 
ATOM   3653 C CA  . ASN B 2 244 ? 134.790 124.629 148.523 1.00 42.11 ? 244 ASN B CA  1 
ATOM   3654 C C   . ASN B 2 244 ? 134.125 123.952 149.717 1.00 42.45 ? 244 ASN B C   1 
ATOM   3655 O O   . ASN B 2 244 ? 134.796 123.648 150.709 1.00 47.85 ? 244 ASN B O   1 
ATOM   3656 C CB  . ASN B 2 244 ? 135.911 125.556 149.010 1.00 39.52 ? 244 ASN B CB  1 
ATOM   3657 C CG  . ASN B 2 244 ? 136.442 126.457 147.912 1.00 40.11 ? 244 ASN B CG  1 
ATOM   3658 O OD1 . ASN B 2 244 ? 136.923 125.982 146.884 1.00 40.51 ? 244 ASN B OD1 1 
ATOM   3659 N ND2 . ASN B 2 244 ? 136.355 127.764 148.123 1.00 39.58 ? 244 ASN B ND2 1 
ATOM   3660 N N   . LEU B 2 245 ? 132.816 123.699 149.643 1.00 31.39 ? 245 LEU B N   1 
ATOM   3661 C CA  . LEU B 2 245 ? 132.121 122.952 150.684 1.00 38.37 ? 245 LEU B CA  1 
ATOM   3662 C C   . LEU B 2 245 ? 132.131 121.447 150.445 1.00 42.43 ? 245 LEU B C   1 
ATOM   3663 O O   . LEU B 2 245 ? 131.594 120.708 151.278 1.00 44.90 ? 245 LEU B O   1 
ATOM   3664 C CB  . LEU B 2 245 ? 130.671 123.432 150.812 1.00 40.06 ? 245 LEU B CB  1 
ATOM   3665 C CG  . LEU B 2 245 ? 130.397 124.932 150.693 1.00 34.64 ? 245 LEU B CG  1 
ATOM   3666 C CD1 . LEU B 2 245 ? 128.904 125.197 150.696 1.00 34.06 ? 245 LEU B CD1 1 
ATOM   3667 C CD2 . LEU B 2 245 ? 131.079 125.689 151.818 1.00 42.19 ? 245 LEU B CD2 1 
ATOM   3668 N N   . VAL B 2 246 ? 132.710 120.978 149.341 1.00 46.04 ? 246 VAL B N   1 
ATOM   3669 C CA  . VAL B 2 246 ? 132.830 119.548 149.072 1.00 49.39 ? 246 VAL B CA  1 
ATOM   3670 C C   . VAL B 2 246 ? 134.191 119.269 148.445 1.00 54.62 ? 246 VAL B C   1 
ATOM   3671 O O   . VAL B 2 246 ? 134.754 120.112 147.747 1.00 53.06 ? 246 VAL B O   1 
ATOM   3672 C CB  . VAL B 2 246 ? 131.692 119.046 148.160 1.00 46.47 ? 246 VAL B CB  1 
ATOM   3673 C CG1 . VAL B 2 246 ? 131.943 117.599 147.738 1.00 45.74 ? 246 VAL B CG1 1 
ATOM   3674 C CG2 . VAL B 2 246 ? 130.345 119.181 148.862 1.00 48.86 ? 246 VAL B CG2 1 
ATOM   3675 O OXT . VAL B 2 246 ? 134.763 118.192 148.619 1.00 55.82 ? 246 VAL B OXT 1 
ATOM   3676 N N   . GLU C 3 21  ? 129.742 86.214  90.182  1.00 83.80 ? 3   GLU C N   1 
ATOM   3677 C CA  . GLU C 3 21  ? 129.831 87.415  89.362  1.00 85.68 ? 3   GLU C CA  1 
ATOM   3678 C C   . GLU C 3 21  ? 130.587 88.504  90.118  1.00 86.15 ? 3   GLU C C   1 
ATOM   3679 O O   . GLU C 3 21  ? 131.633 88.973  89.667  1.00 84.00 ? 3   GLU C O   1 
ATOM   3680 C CB  . GLU C 3 21  ? 128.429 87.898  88.967  1.00 85.99 ? 3   GLU C CB  1 
ATOM   3681 C CG  . GLU C 3 21  ? 128.396 89.126  88.055  1.00 85.86 ? 3   GLU C CG  1 
ATOM   3682 C CD  . GLU C 3 21  ? 129.014 88.864  86.694  1.00 87.16 ? 3   GLU C CD  1 
ATOM   3683 O OE1 . GLU C 3 21  ? 129.081 87.686  86.285  1.00 87.45 ? 3   GLU C OE1 1 
ATOM   3684 O OE2 . GLU C 3 21  ? 129.434 89.838  86.034  1.00 86.63 ? 3   GLU C OE2 1 
ATOM   3685 N N   . LEU C 3 22  ? 130.047 88.903  91.272  1.00 82.18 ? 4   LEU C N   1 
ATOM   3686 C CA  . LEU C 3 22  ? 130.704 89.925  92.081  1.00 80.49 ? 4   LEU C CA  1 
ATOM   3687 C C   . LEU C 3 22  ? 132.047 89.442  92.617  1.00 81.00 ? 4   LEU C C   1 
ATOM   3688 O O   . LEU C 3 22  ? 132.937 90.260  92.878  1.00 78.36 ? 4   LEU C O   1 
ATOM   3689 C CB  . LEU C 3 22  ? 129.795 90.342  93.237  1.00 78.84 ? 4   LEU C CB  1 
ATOM   3690 N N   . ASP C 3 23  ? 132.209 88.129  92.796  1.00 88.31 ? 5   ASP C N   1 
ATOM   3691 C CA  . ASP C 3 23  ? 133.487 87.598  93.259  1.00 88.18 ? 5   ASP C CA  1 
ATOM   3692 C C   . ASP C 3 23  ? 134.594 87.874  92.250  1.00 88.58 ? 5   ASP C C   1 
ATOM   3693 O O   . ASP C 3 23  ? 135.722 88.206  92.633  1.00 87.22 ? 5   ASP C O   1 
ATOM   3694 C CB  . ASP C 3 23  ? 133.364 86.097  93.524  1.00 87.00 ? 5   ASP C CB  1 
ATOM   3695 C CG  . ASP C 3 23  ? 132.431 85.781  94.678  1.00 87.73 ? 5   ASP C CG  1 
ATOM   3696 O OD1 . ASP C 3 23  ? 132.103 86.703  95.455  1.00 87.75 ? 5   ASP C OD1 1 
ATOM   3697 O OD2 . ASP C 3 23  ? 132.024 84.608  94.809  1.00 87.43 ? 5   ASP C OD2 1 
ATOM   3698 N N   . GLN C 3 24  ? 134.293 87.738  90.956  1.00 80.94 ? 6   GLN C N   1 
ATOM   3699 C CA  . GLN C 3 24  ? 135.281 88.055  89.929  1.00 78.03 ? 6   GLN C CA  1 
ATOM   3700 C C   . GLN C 3 24  ? 135.654 89.533  89.968  1.00 79.28 ? 6   GLN C C   1 
ATOM   3701 O O   . GLN C 3 24  ? 136.828 89.890  89.810  1.00 77.05 ? 6   GLN C O   1 
ATOM   3702 C CB  . GLN C 3 24  ? 134.741 87.671  88.551  1.00 77.91 ? 6   GLN C CB  1 
ATOM   3703 C CG  . GLN C 3 24  ? 135.803 87.565  87.468  1.00 79.82 ? 6   GLN C CG  1 
ATOM   3704 C CD  . GLN C 3 24  ? 135.267 87.909  86.092  1.00 79.49 ? 6   GLN C CD  1 
ATOM   3705 O OE1 . GLN C 3 24  ? 134.993 89.071  85.793  1.00 78.92 ? 6   GLN C OE1 1 
ATOM   3706 N NE2 . GLN C 3 24  ? 135.112 86.897  85.246  1.00 76.82 ? 6   GLN C NE2 1 
ATOM   3707 N N   . LEU C 3 25  ? 134.664 90.406  90.171  1.00 78.60 ? 7   LEU C N   1 
ATOM   3708 C CA  . LEU C 3 25  ? 134.949 91.834  90.274  1.00 78.09 ? 7   LEU C CA  1 
ATOM   3709 C C   . LEU C 3 25  ? 135.833 92.131  91.478  1.00 75.31 ? 7   LEU C C   1 
ATOM   3710 O O   . LEU C 3 25  ? 136.765 92.939  91.388  1.00 71.29 ? 7   LEU C O   1 
ATOM   3711 C CB  . LEU C 3 25  ? 133.644 92.628  90.362  1.00 78.87 ? 7   LEU C CB  1 
ATOM   3712 C CG  . LEU C 3 25  ? 132.588 92.361  89.285  1.00 79.98 ? 7   LEU C CG  1 
ATOM   3713 C CD1 . LEU C 3 25  ? 131.338 93.184  89.555  1.00 76.59 ? 7   LEU C CD1 1 
ATOM   3714 C CD2 . LEU C 3 25  ? 133.136 92.657  87.897  1.00 77.41 ? 7   LEU C CD2 1 
ATOM   3715 N N   . ARG C 3 26  ? 135.556 91.489  92.615  1.00 75.90 ? 8   ARG C N   1 
ATOM   3716 C CA  . ARG C 3 26  ? 136.388 91.688  93.797  1.00 75.41 ? 8   ARG C CA  1 
ATOM   3717 C C   . ARG C 3 26  ? 137.808 91.187  93.563  1.00 74.64 ? 8   ARG C C   1 
ATOM   3718 O O   . ARG C 3 26  ? 138.778 91.825  93.989  1.00 71.26 ? 8   ARG C O   1 
ATOM   3719 C CB  . ARG C 3 26  ? 135.762 90.983  95.000  1.00 72.06 ? 8   ARG C CB  1 
ATOM   3720 N N   . GLN C 3 27  ? 137.949 90.039  92.895  1.00 78.42 ? 9   GLN C N   1 
ATOM   3721 C CA  . GLN C 3 27  ? 139.274 89.509  92.587  1.00 78.41 ? 9   GLN C CA  1 
ATOM   3722 C C   . GLN C 3 27  ? 140.049 90.471  91.693  1.00 79.18 ? 9   GLN C C   1 
ATOM   3723 O O   . GLN C 3 27  ? 141.233 90.745  91.929  1.00 77.07 ? 9   GLN C O   1 
ATOM   3724 C CB  . GLN C 3 27  ? 139.132 88.127  91.935  1.00 75.83 ? 9   GLN C CB  1 
ATOM   3725 C CG  . GLN C 3 27  ? 140.333 87.620  91.127  1.00 77.12 ? 9   GLN C CG  1 
ATOM   3726 C CD  . GLN C 3 27  ? 140.112 86.221  90.586  1.00 79.23 ? 9   GLN C CD  1 
ATOM   3727 O OE1 . GLN C 3 27  ? 139.335 85.443  91.141  1.00 77.27 ? 9   GLN C OE1 1 
ATOM   3728 N NE2 . GLN C 3 27  ? 140.791 85.895  89.493  1.00 79.53 ? 9   GLN C NE2 1 
ATOM   3729 N N   . GLU C 3 28  ? 139.390 90.996  90.657  1.00 79.29 ? 10  GLU C N   1 
ATOM   3730 C CA  . GLU C 3 28  ? 140.041 91.959  89.776  1.00 77.38 ? 10  GLU C CA  1 
ATOM   3731 C C   . GLU C 3 28  ? 140.421 93.229  90.524  1.00 76.34 ? 10  GLU C C   1 
ATOM   3732 O O   . GLU C 3 28  ? 141.509 93.775  90.303  1.00 74.79 ? 10  GLU C O   1 
ATOM   3733 C CB  . GLU C 3 28  ? 139.128 92.293  88.597  1.00 73.10 ? 10  GLU C CB  1 
ATOM   3734 N N   . ALA C 3 29  ? 139.543 93.710  91.407  1.00 77.08 ? 11  ALA C N   1 
ATOM   3735 C CA  . ALA C 3 29  ? 139.850 94.904  92.186  1.00 77.24 ? 11  ALA C CA  1 
ATOM   3736 C C   . ALA C 3 29  ? 141.054 94.677  93.089  1.00 76.03 ? 11  ALA C C   1 
ATOM   3737 O O   . ALA C 3 29  ? 141.925 95.545  93.201  1.00 74.69 ? 11  ALA C O   1 
ATOM   3738 C CB  . ALA C 3 29  ? 138.631 95.315  93.012  1.00 74.61 ? 11  ALA C CB  1 
ATOM   3739 N N   . GLU C 3 30  ? 141.122 93.514  93.741  1.00 74.51 ? 12  GLU C N   1 
ATOM   3740 C CA  . GLU C 3 30  ? 142.264 93.216  94.601  1.00 75.02 ? 12  GLU C CA  1 
ATOM   3741 C C   . GLU C 3 30  ? 143.552 93.124  93.793  1.00 75.91 ? 12  GLU C C   1 
ATOM   3742 O O   . GLU C 3 30  ? 144.600 93.631  94.217  1.00 74.27 ? 12  GLU C O   1 
ATOM   3743 C CB  . GLU C 3 30  ? 142.017 91.916  95.365  1.00 73.74 ? 12  GLU C CB  1 
ATOM   3744 N N   . GLN C 3 31  ? 143.496 92.477  92.625  1.00 77.00 ? 13  GLN C N   1 
ATOM   3745 C CA  . GLN C 3 31  ? 144.684 92.367  91.784  1.00 77.41 ? 13  GLN C CA  1 
ATOM   3746 C C   . GLN C 3 31  ? 145.155 93.744  91.329  1.00 78.45 ? 13  GLN C C   1 
ATOM   3747 O O   . GLN C 3 31  ? 146.358 94.038  91.345  1.00 78.41 ? 13  GLN C O   1 
ATOM   3748 C CB  . GLN C 3 31  ? 144.383 91.466  90.583  1.00 78.25 ? 13  GLN C CB  1 
ATOM   3749 C CG  . GLN C 3 31  ? 145.588 91.094  89.716  1.00 78.67 ? 13  GLN C CG  1 
ATOM   3750 C CD  . GLN C 3 31  ? 146.430 89.988  90.324  1.00 80.65 ? 13  GLN C CD  1 
ATOM   3751 O OE1 . GLN C 3 31  ? 146.528 89.863  91.545  1.00 79.64 ? 13  GLN C OE1 1 
ATOM   3752 N NE2 . GLN C 3 31  ? 147.041 89.174  89.471  1.00 80.49 ? 13  GLN C NE2 1 
ATOM   3753 N N   . LEU C 3 32  ? 144.219 94.610  90.937  1.00 75.39 ? 14  LEU C N   1 
ATOM   3754 C CA  . LEU C 3 32  ? 144.594 95.947  90.490  1.00 75.67 ? 14  LEU C CA  1 
ATOM   3755 C C   . LEU C 3 32  ? 145.122 96.784  91.649  1.00 75.65 ? 14  LEU C C   1 
ATOM   3756 O O   . LEU C 3 32  ? 146.020 97.611  91.464  1.00 74.59 ? 14  LEU C O   1 
ATOM   3757 C CB  . LEU C 3 32  ? 143.395 96.624  89.822  1.00 71.94 ? 14  LEU C CB  1 
ATOM   3758 C CG  . LEU C 3 32  ? 143.409 98.140  89.597  1.00 72.88 ? 14  LEU C CG  1 
ATOM   3759 C CD1 . LEU C 3 32  ? 144.503 98.535  88.616  1.00 71.60 ? 14  LEU C CD1 1 
ATOM   3760 C CD2 . LEU C 3 32  ? 142.055 98.566  89.083  1.00 73.13 ? 14  LEU C CD2 1 
ATOM   3761 N N   . LYS C 3 33  ? 144.570 96.595  92.849  1.00 73.48 ? 15  LYS C N   1 
ATOM   3762 C CA  . LYS C 3 33  ? 145.086 97.293  94.021  1.00 73.57 ? 15  LYS C CA  1 
ATOM   3763 C C   . LYS C 3 33  ? 146.517 96.871  94.318  1.00 75.82 ? 15  LYS C C   1 
ATOM   3764 O O   . LYS C 3 33  ? 147.367 97.710  94.641  1.00 72.79 ? 15  LYS C O   1 
ATOM   3765 C CB  . LYS C 3 33  ? 144.177 97.022  95.222  1.00 74.08 ? 15  LYS C CB  1 
ATOM   3766 C CG  . LYS C 3 33  ? 144.669 97.578  96.562  1.00 75.02 ? 15  LYS C CG  1 
ATOM   3767 C CD  . LYS C 3 33  ? 145.034 99.073  96.543  1.00 73.76 ? 15  LYS C CD  1 
ATOM   3768 C CE  . LYS C 3 33  ? 143.946 99.987  95.956  1.00 74.37 ? 15  LYS C CE  1 
ATOM   3769 N NZ  . LYS C 3 33  ? 142.786 100.132 96.879  1.00 76.33 ? 15  LYS C NZ  1 
ATOM   3770 N N   . ASN C 3 34  ? 146.800 95.571  94.217  1.00 81.27 ? 16  ASN C N   1 
ATOM   3771 C CA  . ASN C 3 34  ? 148.171 95.100  94.390  1.00 82.28 ? 16  ASN C CA  1 
ATOM   3772 C C   . ASN C 3 34  ? 149.087 95.694  93.327  1.00 79.65 ? 16  ASN C C   1 
ATOM   3773 O O   . ASN C 3 34  ? 150.223 96.086  93.622  1.00 77.04 ? 16  ASN C O   1 
ATOM   3774 C CB  . ASN C 3 34  ? 148.211 93.573  94.339  1.00 80.75 ? 16  ASN C CB  1 
ATOM   3775 C CG  . ASN C 3 34  ? 149.543 93.010  94.791  1.00 81.43 ? 16  ASN C CG  1 
ATOM   3776 O OD1 . ASN C 3 34  ? 150.458 93.752  95.145  1.00 83.15 ? 16  ASN C OD1 1 
ATOM   3777 N ND2 . ASN C 3 34  ? 149.659 91.688  94.779  1.00 79.18 ? 16  ASN C ND2 1 
ATOM   3778 N N   . GLN C 3 35  ? 148.608 95.764  92.082  1.00 75.79 ? 17  GLN C N   1 
ATOM   3779 C CA  . GLN C 3 35  ? 149.402 96.366  91.014  1.00 75.88 ? 17  GLN C CA  1 
ATOM   3780 C C   . GLN C 3 35  ? 149.700 97.832  91.307  1.00 74.59 ? 17  GLN C C   1 
ATOM   3781 O O   . GLN C 3 35  ? 150.828 98.297  91.106  1.00 74.11 ? 17  GLN C O   1 
ATOM   3782 C CB  . GLN C 3 35  ? 148.667 96.223  89.679  1.00 76.24 ? 17  GLN C CB  1 
ATOM   3783 C CG  . GLN C 3 35  ? 149.531 96.474  88.442  1.00 78.00 ? 17  GLN C CG  1 
ATOM   3784 C CD  . GLN C 3 35  ? 149.645 97.945  88.073  1.00 78.69 ? 17  GLN C CD  1 
ATOM   3785 O OE1 . GLN C 3 35  ? 148.711 98.724  88.266  1.00 77.14 ? 17  GLN C OE1 1 
ATOM   3786 N NE2 . GLN C 3 35  ? 150.798 98.331  87.538  1.00 75.60 ? 17  GLN C NE2 1 
ATOM   3787 N N   . ILE C 3 36  ? 148.698 98.577  91.780  1.00 72.25 ? 18  ILE C N   1 
ATOM   3788 C CA  . ILE C 3 36  ? 148.893 99.993  92.080  1.00 76.46 ? 18  ILE C CA  1 
ATOM   3789 C C   . ILE C 3 36  ? 149.883 100.159 93.224  1.00 76.17 ? 18  ILE C C   1 
ATOM   3790 O O   . ILE C 3 36  ? 150.747 101.044 93.192  1.00 71.87 ? 18  ILE C O   1 
ATOM   3791 C CB  . ILE C 3 36  ? 147.541 100.664 92.396  1.00 76.39 ? 18  ILE C CB  1 
ATOM   3792 C CG1 . ILE C 3 36  ? 146.706 100.790 91.116  1.00 75.63 ? 18  ILE C CG1 1 
ATOM   3793 C CG2 . ILE C 3 36  ? 147.759 102.044 93.045  1.00 71.58 ? 18  ILE C CG2 1 
ATOM   3794 C CD1 . ILE C 3 36  ? 145.251 101.165 91.351  1.00 77.49 ? 18  ILE C CD1 1 
ATOM   3795 N N   . ARG C 3 37  ? 149.765 99.324  94.259  1.00 75.27 ? 19  ARG C N   1 
ATOM   3796 C CA  . ARG C 3 37  ? 150.696 99.407  95.380  1.00 73.17 ? 19  ARG C CA  1 
ATOM   3797 C C   . ARG C 3 37  ? 152.121 99.108  94.933  1.00 74.88 ? 19  ARG C C   1 
ATOM   3798 O O   . ARG C 3 37  ? 153.064 99.801  95.334  1.00 72.02 ? 19  ARG C O   1 
ATOM   3799 C CB  . ARG C 3 37  ? 150.269 98.444  96.487  1.00 71.93 ? 19  ARG C CB  1 
ATOM   3800 N N   . ASP C 3 38  ? 152.299 98.084  94.094  1.00 73.16 ? 20  ASP C N   1 
ATOM   3801 C CA  . ASP C 3 38  ? 153.634 97.761  93.603  1.00 69.91 ? 20  ASP C CA  1 
ATOM   3802 C C   . ASP C 3 38  ? 154.196 98.892  92.750  1.00 68.22 ? 20  ASP C C   1 
ATOM   3803 O O   . ASP C 3 38  ? 155.376 99.241  92.869  1.00 65.42 ? 20  ASP C O   1 
ATOM   3804 C CB  . ASP C 3 38  ? 153.600 96.458  92.806  1.00 72.53 ? 20  ASP C CB  1 
ATOM   3805 C CG  . ASP C 3 38  ? 154.977 96.024  92.342  1.00 73.71 ? 20  ASP C CG  1 
ATOM   3806 O OD1 . ASP C 3 38  ? 155.776 95.574  93.189  1.00 73.75 ? 20  ASP C OD1 1 
ATOM   3807 O OD2 . ASP C 3 38  ? 155.260 96.134  91.130  1.00 72.70 ? 20  ASP C OD2 1 
ATOM   3808 N N   . ALA C 3 39  ? 153.366 99.477  91.883  1.00 69.56 ? 21  ALA C N   1 
ATOM   3809 C CA  . ALA C 3 39  ? 153.834 100.573 91.041  1.00 71.51 ? 21  ALA C CA  1 
ATOM   3810 C C   . ALA C 3 39  ? 154.215 101.787 91.878  1.00 69.26 ? 21  ALA C C   1 
ATOM   3811 O O   . ALA C 3 39  ? 155.211 102.461 91.591  1.00 69.33 ? 21  ALA C O   1 
ATOM   3812 C CB  . ALA C 3 39  ? 152.760 100.944 90.019  1.00 69.54 ? 21  ALA C CB  1 
ATOM   3813 N N   . ARG C 3 40  ? 153.433 102.082 92.918  1.00 62.22 ? 22  ARG C N   1 
ATOM   3814 C CA  . ARG C 3 40  ? 153.741 103.221 93.773  1.00 61.85 ? 22  ARG C CA  1 
ATOM   3815 C C   . ARG C 3 40  ? 154.993 102.976 94.604  1.00 63.08 ? 22  ARG C C   1 
ATOM   3816 O O   . ARG C 3 40  ? 155.751 103.915 94.869  1.00 64.24 ? 22  ARG C O   1 
ATOM   3817 C CB  . ARG C 3 40  ? 152.552 103.524 94.682  1.00 62.62 ? 22  ARG C CB  1 
ATOM   3818 C CG  . ARG C 3 40  ? 152.770 104.703 95.623  1.00 54.31 ? 22  ARG C CG  1 
ATOM   3819 C CD  . ARG C 3 40  ? 151.475 105.455 95.943  1.00 56.64 ? 22  ARG C CD  1 
ATOM   3820 N NE  . ARG C 3 40  ? 150.305 104.588 96.049  1.00 61.10 ? 22  ARG C NE  1 
ATOM   3821 C CZ  . ARG C 3 40  ? 149.064 105.014 96.248  1.00 62.24 ? 22  ARG C CZ  1 
ATOM   3822 N NH1 . ARG C 3 40  ? 148.779 106.302 96.367  1.00 58.26 ? 22  ARG C NH1 1 
ATOM   3823 N NH2 . ARG C 3 40  ? 148.079 104.123 96.329  1.00 61.18 ? 22  ARG C NH2 1 
ATOM   3824 N N   . LYS C 3 41  ? 155.224 101.731 95.027  1.00 65.31 ? 23  LYS C N   1 
ATOM   3825 C CA  . LYS C 3 41  ? 156.416 101.420 95.808  1.00 65.15 ? 23  LYS C CA  1 
ATOM   3826 C C   . LYS C 3 41  ? 157.667 101.347 94.942  1.00 63.13 ? 23  LYS C C   1 
ATOM   3827 O O   . LYS C 3 41  ? 158.774 101.563 95.446  1.00 60.21 ? 23  LYS C O   1 
ATOM   3828 C CB  . LYS C 3 41  ? 156.222 100.096 96.555  1.00 65.19 ? 23  LYS C CB  1 
ATOM   3829 C CG  . LYS C 3 41  ? 156.912 99.982  97.928  1.00 64.83 ? 23  LYS C CG  1 
ATOM   3830 C CD  . LYS C 3 41  ? 156.599 101.112 98.932  1.00 64.84 ? 23  LYS C CD  1 
ATOM   3831 C CE  . LYS C 3 41  ? 155.119 101.496 98.998  1.00 63.28 ? 23  LYS C CE  1 
ATOM   3832 N NZ  . LYS C 3 41  ? 154.886 102.599 99.968  1.00 61.37 ? 23  LYS C NZ  1 
ATOM   3833 N N   . ALA C 3 42  ? 157.517 101.037 93.652  1.00 66.09 ? 24  ALA C N   1 
ATOM   3834 C CA  . ALA C 3 42  ? 158.679 100.974 92.773  1.00 66.55 ? 24  ALA C CA  1 
ATOM   3835 C C   . ALA C 3 42  ? 159.356 102.331 92.634  1.00 65.18 ? 24  ALA C C   1 
ATOM   3836 O O   . ALA C 3 42  ? 160.573 102.397 92.427  1.00 69.12 ? 24  ALA C O   1 
ATOM   3837 C CB  . ALA C 3 42  ? 158.267 100.447 91.399  1.00 66.31 ? 24  ALA C CB  1 
ATOM   3838 N N   . CYS C 3 43  ? 158.596 103.417 92.747  1.00 61.09 ? 25  CYS C N   1 
ATOM   3839 C CA  . CYS C 3 43  ? 159.130 104.764 92.596  1.00 62.04 ? 25  CYS C CA  1 
ATOM   3840 C C   . CYS C 3 43  ? 159.761 105.309 93.874  1.00 63.44 ? 25  CYS C C   1 
ATOM   3841 O O   . CYS C 3 43  ? 160.288 106.426 93.853  1.00 64.20 ? 25  CYS C O   1 
ATOM   3842 C CB  . CYS C 3 43  ? 158.023 105.713 92.127  1.00 60.71 ? 25  CYS C CB  1 
ATOM   3843 S SG  . CYS C 3 43  ? 157.115 106.517 93.462  1.00 71.12 ? 25  CYS C SG  1 
ATOM   3844 N N   . ALA C 3 44  ? 159.726 104.559 94.976  1.00 63.54 ? 26  ALA C N   1 
ATOM   3845 C CA  . ALA C 3 44  ? 160.358 104.958 96.232  1.00 61.84 ? 26  ALA C CA  1 
ATOM   3846 C C   . ALA C 3 44  ? 161.763 104.368 96.258  1.00 66.34 ? 26  ALA C C   1 
ATOM   3847 O O   . ALA C 3 44  ? 161.935 103.156 96.414  1.00 67.98 ? 26  ALA C O   1 
ATOM   3848 C CB  . ALA C 3 44  ? 159.535 104.490 97.426  1.00 60.85 ? 26  ALA C CB  1 
ATOM   3849 N N   . ASP C 3 45  ? 162.768 105.234 96.110  1.00 68.80 ? 27  ASP C N   1 
ATOM   3850 C CA  . ASP C 3 45  ? 164.172 104.827 96.078  1.00 71.42 ? 27  ASP C CA  1 
ATOM   3851 C C   . ASP C 3 45  ? 164.954 105.407 97.252  1.00 70.28 ? 27  ASP C C   1 
ATOM   3852 O O   . ASP C 3 45  ? 165.715 104.688 97.906  1.00 72.65 ? 27  ASP C O   1 
ATOM   3853 C CB  . ASP C 3 45  ? 164.816 105.240 94.744  1.00 71.02 ? 27  ASP C CB  1 
ATOM   3854 C CG  . ASP C 3 45  ? 164.551 106.691 94.382  1.00 72.90 ? 27  ASP C CG  1 
ATOM   3855 O OD1 . ASP C 3 45  ? 164.175 107.475 95.277  1.00 72.95 ? 27  ASP C OD1 1 
ATOM   3856 O OD2 . ASP C 3 45  ? 164.716 107.047 93.197  1.00 71.21 ? 27  ASP C OD2 1 
ATOM   3857 N N   . ALA C 3 46  ? 164.781 106.700 97.525  1.00 65.97 ? 28  ALA C N   1 
ATOM   3858 C CA  . ALA C 3 46  ? 165.449 107.378 98.629  1.00 65.53 ? 28  ALA C CA  1 
ATOM   3859 C C   . ALA C 3 46  ? 164.420 108.165 99.422  1.00 63.01 ? 28  ALA C C   1 
ATOM   3860 O O   . ALA C 3 46  ? 163.637 108.926 98.846  1.00 64.42 ? 28  ALA C O   1 
ATOM   3861 C CB  . ALA C 3 46  ? 166.551 108.311 98.121  1.00 64.17 ? 28  ALA C CB  1 
ATOM   3862 N N   . THR C 3 47  ? 164.426 107.984 100.739 1.00 65.35 ? 29  THR C N   1 
ATOM   3863 C CA  . THR C 3 47  ? 163.498 108.694 101.601 1.00 67.39 ? 29  THR C CA  1 
ATOM   3864 C C   . THR C 3 47  ? 163.968 110.130 101.821 1.00 65.01 ? 29  THR C C   1 
ATOM   3865 O O   . THR C 3 47  ? 165.144 110.464 101.654 1.00 64.58 ? 29  THR C O   1 
ATOM   3866 C CB  . THR C 3 47  ? 163.348 107.973 102.940 1.00 67.97 ? 29  THR C CB  1 
ATOM   3867 O OG1 . THR C 3 47  ? 164.625 107.873 103.582 1.00 65.69 ? 29  THR C OG1 1 
ATOM   3868 C CG2 . THR C 3 47  ? 162.774 106.579 102.734 1.00 64.63 ? 29  THR C CG2 1 
ATOM   3869 N N   . LEU C 3 48  ? 163.022 110.989 102.210 1.00 50.00 ? 30  LEU C N   1 
ATOM   3870 C CA  . LEU C 3 48  ? 163.332 112.407 102.367 1.00 52.03 ? 30  LEU C CA  1 
ATOM   3871 C C   . LEU C 3 48  ? 164.311 112.638 103.515 1.00 58.07 ? 30  LEU C C   1 
ATOM   3872 O O   . LEU C 3 48  ? 165.069 113.615 103.501 1.00 58.84 ? 30  LEU C O   1 
ATOM   3873 C CB  . LEU C 3 48  ? 162.041 113.199 102.585 1.00 49.90 ? 30  LEU C CB  1 
ATOM   3874 C CG  . LEU C 3 48  ? 162.182 114.718 102.731 1.00 49.29 ? 30  LEU C CG  1 
ATOM   3875 C CD1 . LEU C 3 48  ? 161.163 115.457 101.878 1.00 46.51 ? 30  LEU C CD1 1 
ATOM   3876 C CD2 . LEU C 3 48  ? 162.045 115.127 104.171 1.00 45.72 ? 30  LEU C CD2 1 
ATOM   3877 N N   . SER C 3 49  ? 164.317 111.746 104.511 1.00 63.82 ? 31  SER C N   1 
ATOM   3878 C CA  . SER C 3 49  ? 165.189 111.925 105.668 1.00 62.24 ? 31  SER C CA  1 
ATOM   3879 C C   . SER C 3 49  ? 166.659 111.894 105.271 1.00 61.47 ? 31  SER C C   1 
ATOM   3880 O O   . SER C 3 49  ? 167.428 112.788 105.643 1.00 59.30 ? 31  SER C O   1 
ATOM   3881 C CB  . SER C 3 49  ? 164.908 110.839 106.706 1.00 62.83 ? 31  SER C CB  1 
ATOM   3882 O OG  . SER C 3 49  ? 163.673 111.058 107.360 1.00 59.47 ? 31  SER C OG  1 
ATOM   3883 N N   . GLN C 3 50  ? 167.069 110.876 104.512 1.00 63.86 ? 32  GLN C N   1 
ATOM   3884 C CA  . GLN C 3 50  ? 168.478 110.760 104.150 1.00 67.06 ? 32  GLN C CA  1 
ATOM   3885 C C   . GLN C 3 50  ? 168.893 111.805 103.122 1.00 65.63 ? 32  GLN C C   1 
ATOM   3886 O O   . GLN C 3 50  ? 170.092 112.068 102.979 1.00 65.21 ? 32  GLN C O   1 
ATOM   3887 C CB  . GLN C 3 50  ? 168.829 109.361 103.608 1.00 66.14 ? 32  GLN C CB  1 
ATOM   3888 C CG  . GLN C 3 50  ? 167.865 108.694 102.607 1.00 62.93 ? 32  GLN C CG  1 
ATOM   3889 C CD  . GLN C 3 50  ? 168.000 107.183 102.607 1.00 64.85 ? 32  GLN C CD  1 
ATOM   3890 O OE1 . GLN C 3 50  ? 168.910 106.630 101.990 1.00 64.85 ? 32  GLN C OE1 1 
ATOM   3891 N NE2 . GLN C 3 50  ? 167.096 106.509 103.307 1.00 64.79 ? 32  GLN C NE2 1 
ATOM   3892 N N   . ILE C 3 51  ? 167.942 112.403 102.408 1.00 60.16 ? 33  ILE C N   1 
ATOM   3893 C CA  . ILE C 3 51  ? 168.257 113.487 101.483 1.00 60.21 ? 33  ILE C CA  1 
ATOM   3894 C C   . ILE C 3 51  ? 168.437 114.804 102.225 1.00 63.34 ? 33  ILE C C   1 
ATOM   3895 O O   . ILE C 3 51  ? 169.354 115.571 101.924 1.00 66.88 ? 33  ILE C O   1 
ATOM   3896 C CB  . ILE C 3 51  ? 167.163 113.592 100.399 1.00 57.30 ? 33  ILE C CB  1 
ATOM   3897 C CG1 . ILE C 3 51  ? 167.229 112.379 99.465  1.00 63.62 ? 33  ILE C CG1 1 
ATOM   3898 C CG2 . ILE C 3 51  ? 167.313 114.896 99.602  1.00 57.54 ? 33  ILE C CG2 1 
ATOM   3899 C CD1 . ILE C 3 51  ? 166.005 112.194 98.590  1.00 64.17 ? 33  ILE C CD1 1 
ATOM   3900 N N   . THR C 3 52  ? 167.571 115.083 103.199 1.00 59.67 ? 34  THR C N   1 
ATOM   3901 C CA  . THR C 3 52  ? 167.615 116.322 103.966 1.00 63.80 ? 34  THR C CA  1 
ATOM   3902 C C   . THR C 3 52  ? 168.493 116.226 105.213 1.00 64.57 ? 34  THR C C   1 
ATOM   3903 O O   . THR C 3 52  ? 168.380 117.083 106.098 1.00 62.59 ? 34  THR C O   1 
ATOM   3904 C CB  . THR C 3 52  ? 166.195 116.735 104.364 1.00 57.71 ? 34  THR C CB  1 
ATOM   3905 O OG1 . THR C 3 52  ? 166.201 118.084 104.847 1.00 57.46 ? 34  THR C OG1 1 
ATOM   3906 C CG2 . THR C 3 52  ? 165.647 115.814 105.445 1.00 58.06 ? 34  THR C CG2 1 
ATOM   3907 N N   . ASN C 3 53  ? 169.353 115.208 105.309 1.00 67.27 ? 35  ASN C N   1 
ATOM   3908 C CA  . ASN C 3 53  ? 170.157 115.031 106.514 1.00 67.11 ? 35  ASN C CA  1 
ATOM   3909 C C   . ASN C 3 53  ? 171.136 116.183 106.706 1.00 66.46 ? 35  ASN C C   1 
ATOM   3910 O O   . ASN C 3 53  ? 171.273 116.710 107.816 1.00 64.75 ? 35  ASN C O   1 
ATOM   3911 C CB  . ASN C 3 53  ? 170.905 113.700 106.450 1.00 66.12 ? 35  ASN C CB  1 
ATOM   3912 N N   . ASN C 3 54  ? 171.816 116.593 105.636 1.00 67.52 ? 36  ASN C N   1 
ATOM   3913 C CA  . ASN C 3 54  ? 172.855 117.623 105.722 1.00 69.85 ? 36  ASN C CA  1 
ATOM   3914 C C   . ASN C 3 54  ? 172.257 118.989 105.389 1.00 68.19 ? 36  ASN C C   1 
ATOM   3915 O O   . ASN C 3 54  ? 172.534 119.603 104.358 1.00 67.04 ? 36  ASN C O   1 
ATOM   3916 C CB  . ASN C 3 54  ? 174.030 117.277 104.806 1.00 70.73 ? 36  ASN C CB  1 
ATOM   3917 C CG  . ASN C 3 54  ? 173.613 117.053 103.363 1.00 72.04 ? 36  ASN C CG  1 
ATOM   3918 O OD1 . ASN C 3 54  ? 172.438 117.175 103.016 1.00 68.58 ? 36  ASN C OD1 1 
ATOM   3919 N ND2 . ASN C 3 54  ? 174.580 116.727 102.513 1.00 70.80 ? 36  ASN C ND2 1 
ATOM   3920 N N   . ILE C 3 55  ? 171.414 119.458 106.306 1.00 61.54 ? 37  ILE C N   1 
ATOM   3921 C CA  . ILE C 3 55  ? 170.792 120.774 106.224 1.00 60.29 ? 37  ILE C CA  1 
ATOM   3922 C C   . ILE C 3 55  ? 170.929 121.439 107.584 1.00 61.79 ? 37  ILE C C   1 
ATOM   3923 O O   . ILE C 3 55  ? 170.694 120.802 108.617 1.00 60.68 ? 37  ILE C O   1 
ATOM   3924 C CB  . ILE C 3 55  ? 169.308 120.689 105.814 1.00 58.69 ? 37  ILE C CB  1 
ATOM   3925 C CG1 . ILE C 3 55  ? 169.155 120.095 104.405 1.00 57.64 ? 37  ILE C CG1 1 
ATOM   3926 C CG2 . ILE C 3 55  ? 168.646 122.059 105.913 1.00 57.78 ? 37  ILE C CG2 1 
ATOM   3927 C CD1 . ILE C 3 55  ? 169.698 120.952 103.263 1.00 59.79 ? 37  ILE C CD1 1 
ATOM   3928 N N   . ASP C 3 56  ? 171.314 122.709 107.583 1.00 58.08 ? 38  ASP C N   1 
ATOM   3929 C CA  . ASP C 3 56  ? 171.432 123.442 108.832 1.00 57.15 ? 38  ASP C CA  1 
ATOM   3930 C C   . ASP C 3 56  ? 170.048 123.564 109.471 1.00 55.66 ? 38  ASP C C   1 
ATOM   3931 O O   . ASP C 3 56  ? 169.113 124.037 108.810 1.00 51.21 ? 38  ASP C O   1 
ATOM   3932 C CB  . ASP C 3 56  ? 172.024 124.828 108.582 1.00 57.20 ? 38  ASP C CB  1 
ATOM   3933 C CG  . ASP C 3 56  ? 172.796 125.360 109.775 1.00 59.31 ? 38  ASP C CG  1 
ATOM   3934 O OD1 . ASP C 3 56  ? 172.258 125.324 110.901 1.00 57.09 ? 38  ASP C OD1 1 
ATOM   3935 O OD2 . ASP C 3 56  ? 173.944 125.813 109.585 1.00 59.64 ? 38  ASP C OD2 1 
ATOM   3936 N N   . PRO C 3 57  ? 169.862 123.152 110.730 1.00 54.73 ? 39  PRO C N   1 
ATOM   3937 C CA  . PRO C 3 57  ? 168.526 123.253 111.327 1.00 50.16 ? 39  PRO C CA  1 
ATOM   3938 C C   . PRO C 3 57  ? 168.106 124.701 111.520 1.00 50.71 ? 39  PRO C C   1 
ATOM   3939 O O   . PRO C 3 57  ? 168.915 125.629 111.444 1.00 52.32 ? 39  PRO C O   1 
ATOM   3940 C CB  . PRO C 3 57  ? 168.677 122.535 112.673 1.00 51.15 ? 39  PRO C CB  1 
ATOM   3941 C CG  . PRO C 3 57  ? 170.117 122.622 112.984 1.00 54.19 ? 39  PRO C CG  1 
ATOM   3942 C CD  . PRO C 3 57  ? 170.809 122.517 111.667 1.00 56.20 ? 39  PRO C CD  1 
ATOM   3943 N N   . VAL C 3 58  ? 166.807 124.885 111.781 1.00 50.55 ? 40  VAL C N   1 
ATOM   3944 C CA  . VAL C 3 58  ? 166.276 126.220 112.055 1.00 48.66 ? 40  VAL C CA  1 
ATOM   3945 C C   . VAL C 3 58  ? 166.572 126.669 113.478 1.00 52.03 ? 40  VAL C C   1 
ATOM   3946 O O   . VAL C 3 58  ? 166.287 127.821 113.827 1.00 53.37 ? 40  VAL C O   1 
ATOM   3947 C CB  . VAL C 3 58  ? 164.755 126.261 111.775 1.00 47.74 ? 40  VAL C CB  1 
ATOM   3948 C CG1 . VAL C 3 58  ? 163.970 125.356 112.733 1.00 45.69 ? 40  VAL C CG1 1 
ATOM   3949 C CG2 . VAL C 3 58  ? 164.208 127.689 111.820 1.00 45.49 ? 40  VAL C CG2 1 
ATOM   3950 N N   . GLY C 3 59  ? 167.189 125.819 114.298 1.00 62.25 ? 41  GLY C N   1 
ATOM   3951 C CA  . GLY C 3 59  ? 167.482 126.199 115.665 1.00 62.99 ? 41  GLY C CA  1 
ATOM   3952 C C   . GLY C 3 59  ? 166.237 126.199 116.537 1.00 59.69 ? 41  GLY C C   1 
ATOM   3953 O O   . GLY C 3 59  ? 165.402 125.295 116.477 1.00 58.80 ? 41  GLY C O   1 
ATOM   3954 N N   . ARG C 3 60  ? 166.127 127.236 117.363 1.00 65.82 ? 42  ARG C N   1 
ATOM   3955 C CA  . ARG C 3 60  ? 165.024 127.413 118.296 1.00 68.18 ? 42  ARG C CA  1 
ATOM   3956 C C   . ARG C 3 60  ? 164.357 128.755 118.035 1.00 68.58 ? 42  ARG C C   1 
ATOM   3957 O O   . ARG C 3 60  ? 165.035 129.747 117.750 1.00 70.37 ? 42  ARG C O   1 
ATOM   3958 C CB  . ARG C 3 60  ? 165.517 127.344 119.746 1.00 70.93 ? 42  ARG C CB  1 
ATOM   3959 C CG  . ARG C 3 60  ? 164.414 127.404 120.792 1.00 68.11 ? 42  ARG C CG  1 
ATOM   3960 C CD  . ARG C 3 60  ? 164.849 126.746 122.095 1.00 69.85 ? 42  ARG C CD  1 
ATOM   3961 N NE  . ARG C 3 60  ? 164.356 127.467 123.263 1.00 71.30 ? 42  ARG C NE  1 
ATOM   3962 C CZ  . ARG C 3 60  ? 163.084 127.528 123.638 1.00 71.96 ? 42  ARG C CZ  1 
ATOM   3963 N NH1 . ARG C 3 60  ? 162.127 126.914 122.958 1.00 69.22 ? 42  ARG C NH1 1 
ATOM   3964 N NH2 . ARG C 3 60  ? 162.764 128.223 124.726 1.00 70.90 ? 42  ARG C NH2 1 
ATOM   3965 N N   . ILE C 3 61  ? 163.025 128.777 118.123 1.00 57.83 ? 43  ILE C N   1 
ATOM   3966 C CA  . ILE C 3 61  ? 162.244 129.994 117.955 1.00 60.59 ? 43  ILE C CA  1 
ATOM   3967 C C   . ILE C 3 61  ? 161.244 130.108 119.097 1.00 58.73 ? 43  ILE C C   1 
ATOM   3968 O O   . ILE C 3 61  ? 160.808 129.112 119.678 1.00 53.67 ? 43  ILE C O   1 
ATOM   3969 C CB  . ILE C 3 61  ? 161.519 130.046 116.589 1.00 52.96 ? 43  ILE C CB  1 
ATOM   3970 C CG1 . ILE C 3 61  ? 160.663 128.796 116.357 1.00 48.45 ? 43  ILE C CG1 1 
ATOM   3971 C CG2 . ILE C 3 61  ? 162.535 130.196 115.465 1.00 46.97 ? 43  ILE C CG2 1 
ATOM   3972 C CD1 . ILE C 3 61  ? 159.614 128.975 115.291 1.00 49.33 ? 43  ILE C CD1 1 
ATOM   3973 N N   . GLN C 3 62  ? 160.886 131.351 119.409 1.00 55.78 ? 44  GLN C N   1 
ATOM   3974 C CA  . GLN C 3 62  ? 159.873 131.646 120.412 1.00 53.20 ? 44  GLN C CA  1 
ATOM   3975 C C   . GLN C 3 62  ? 158.989 132.756 119.871 1.00 50.96 ? 44  GLN C C   1 
ATOM   3976 O O   . GLN C 3 62  ? 159.497 133.773 119.390 1.00 46.28 ? 44  GLN C O   1 
ATOM   3977 C CB  . GLN C 3 62  ? 160.509 132.065 121.742 1.00 50.48 ? 44  GLN C CB  1 
ATOM   3978 N N   . MET C 3 63  ? 157.677 132.546 119.939 1.00 38.10 ? 45  MET C N   1 
ATOM   3979 C CA  . MET C 3 63  ? 156.690 133.525 119.507 1.00 33.22 ? 45  MET C CA  1 
ATOM   3980 C C   . MET C 3 63  ? 155.734 133.802 120.654 1.00 34.53 ? 45  MET C C   1 
ATOM   3981 O O   . MET C 3 63  ? 155.161 132.876 121.234 1.00 35.10 ? 45  MET C O   1 
ATOM   3982 C CB  . MET C 3 63  ? 155.912 133.035 118.284 1.00 37.73 ? 45  MET C CB  1 
ATOM   3983 C CG  . MET C 3 63  ? 156.758 132.277 117.275 1.00 45.86 ? 45  MET C CG  1 
ATOM   3984 S SD  . MET C 3 63  ? 155.958 132.095 115.666 1.00 50.23 ? 45  MET C SD  1 
ATOM   3985 C CE  . MET C 3 63  ? 154.518 131.126 116.098 1.00 35.12 ? 45  MET C CE  1 
ATOM   3986 N N   . ARG C 3 64  ? 155.572 135.082 120.973 1.00 34.15 ? 46  ARG C N   1 
ATOM   3987 C CA  . ARG C 3 64  ? 154.700 135.536 122.044 1.00 37.79 ? 46  ARG C CA  1 
ATOM   3988 C C   . ARG C 3 64  ? 153.421 136.101 121.447 1.00 29.80 ? 46  ARG C C   1 
ATOM   3989 O O   . ARG C 3 64  ? 153.454 136.762 120.404 1.00 32.09 ? 46  ARG C O   1 
ATOM   3990 C CB  . ARG C 3 64  ? 155.392 136.601 122.899 1.00 30.17 ? 46  ARG C CB  1 
ATOM   3991 N N   . THR C 3 65  ? 152.296 135.818 122.100 1.00 23.22 ? 47  THR C N   1 
ATOM   3992 C CA  . THR C 3 65  ? 151.024 136.385 121.668 1.00 21.06 ? 47  THR C CA  1 
ATOM   3993 C C   . THR C 3 65  ? 151.104 137.906 121.653 1.00 24.68 ? 47  THR C C   1 
ATOM   3994 O O   . THR C 3 65  ? 151.396 138.538 122.671 1.00 38.39 ? 47  THR C O   1 
ATOM   3995 C CB  . THR C 3 65  ? 149.869 135.931 122.571 1.00 28.29 ? 47  THR C CB  1 
ATOM   3996 O OG1 . THR C 3 65  ? 148.723 136.751 122.316 1.00 26.43 ? 47  THR C OG1 1 
ATOM   3997 C CG2 . THR C 3 65  ? 150.214 136.015 124.063 1.00 35.40 ? 47  THR C CG2 1 
ATOM   3998 N N   . ARG C 3 66  ? 150.854 138.490 120.483 1.00 23.42 ? 48  ARG C N   1 
ATOM   3999 C CA  . ARG C 3 66  ? 150.953 139.931 120.304 1.00 23.74 ? 48  ARG C CA  1 
ATOM   4000 C C   . ARG C 3 66  ? 149.640 140.651 120.555 1.00 29.53 ? 48  ARG C C   1 
ATOM   4001 O O   . ARG C 3 66  ? 149.661 141.801 121.006 1.00 35.54 ? 48  ARG C O   1 
ATOM   4002 C CB  . ARG C 3 66  ? 151.439 140.267 118.889 1.00 20.22 ? 48  ARG C CB  1 
ATOM   4003 C CG  . ARG C 3 66  ? 152.762 139.621 118.496 1.00 27.15 ? 48  ARG C CG  1 
ATOM   4004 C CD  . ARG C 3 66  ? 153.935 140.552 118.714 1.00 36.42 ? 48  ARG C CD  1 
ATOM   4005 N NE  . ARG C 3 66  ? 155.186 139.806 118.803 1.00 35.55 ? 48  ARG C NE  1 
ATOM   4006 C CZ  . ARG C 3 66  ? 156.388 140.272 118.483 1.00 40.05 ? 48  ARG C CZ  1 
ATOM   4007 N NH1 . ARG C 3 66  ? 156.570 141.517 118.073 1.00 40.00 ? 48  ARG C NH1 1 
ATOM   4008 N NH2 . ARG C 3 66  ? 157.441 139.467 118.587 1.00 39.35 ? 48  ARG C NH2 1 
ATOM   4009 N N   . ARG C 3 67  ? 148.507 140.014 120.265 1.00 25.80 ? 49  ARG C N   1 
ATOM   4010 C CA  . ARG C 3 67  ? 147.202 140.589 120.555 1.00 31.12 ? 49  ARG C CA  1 
ATOM   4011 C C   . ARG C 3 67  ? 146.251 139.470 120.946 1.00 25.53 ? 49  ARG C C   1 
ATOM   4012 O O   . ARG C 3 67  ? 146.381 138.329 120.499 1.00 31.11 ? 49  ARG C O   1 
ATOM   4013 C CB  . ARG C 3 67  ? 146.650 141.377 119.361 1.00 31.73 ? 49  ARG C CB  1 
ATOM   4014 C CG  . ARG C 3 67  ? 147.552 142.512 118.905 1.00 38.73 ? 49  ARG C CG  1 
ATOM   4015 C CD  . ARG C 3 67  ? 146.948 143.302 117.761 1.00 32.67 ? 49  ARG C CD  1 
ATOM   4016 N NE  . ARG C 3 67  ? 147.171 144.737 117.901 1.00 36.19 ? 49  ARG C NE  1 
ATOM   4017 C CZ  . ARG C 3 67  ? 148.358 145.331 117.942 1.00 36.86 ? 49  ARG C CZ  1 
ATOM   4018 N NH1 . ARG C 3 67  ? 149.487 144.650 117.811 1.00 30.58 ? 49  ARG C NH1 1 
ATOM   4019 N NH2 . ARG C 3 67  ? 148.417 146.648 118.114 1.00 38.13 ? 49  ARG C NH2 1 
ATOM   4020 N N   . THR C 3 68  ? 145.289 139.817 121.798 1.00 22.28 ? 50  THR C N   1 
ATOM   4021 C CA  . THR C 3 68  ? 144.266 138.881 122.251 1.00 25.47 ? 50  THR C CA  1 
ATOM   4022 C C   . THR C 3 68  ? 142.920 139.557 122.064 1.00 30.68 ? 50  THR C C   1 
ATOM   4023 O O   . THR C 3 68  ? 142.631 140.554 122.731 1.00 34.95 ? 50  THR C O   1 
ATOM   4024 C CB  . THR C 3 68  ? 144.476 138.493 123.715 1.00 35.92 ? 50  THR C CB  1 
ATOM   4025 O OG1 . THR C 3 68  ? 145.703 137.769 123.848 1.00 35.85 ? 50  THR C OG1 1 
ATOM   4026 C CG2 . THR C 3 68  ? 143.330 137.624 124.212 1.00 32.50 ? 50  THR C CG2 1 
ATOM   4027 N N   . LEU C 3 69  ? 142.106 139.017 121.165 1.00 27.31 ? 51  LEU C N   1 
ATOM   4028 C CA  . LEU C 3 69  ? 140.840 139.625 120.775 1.00 31.63 ? 51  LEU C CA  1 
ATOM   4029 C C   . LEU C 3 69  ? 139.723 139.016 121.611 1.00 33.22 ? 51  LEU C C   1 
ATOM   4030 O O   . LEU C 3 69  ? 139.370 137.846 121.431 1.00 24.20 ? 51  LEU C O   1 
ATOM   4031 C CB  . LEU C 3 69  ? 140.588 139.439 119.281 1.00 31.31 ? 51  LEU C CB  1 
ATOM   4032 C CG  . LEU C 3 69  ? 141.730 139.905 118.369 1.00 27.77 ? 51  LEU C CG  1 
ATOM   4033 C CD1 . LEU C 3 69  ? 142.648 138.765 117.978 1.00 27.71 ? 51  LEU C CD1 1 
ATOM   4034 C CD2 . LEU C 3 69  ? 141.188 140.585 117.126 1.00 28.25 ? 51  LEU C CD2 1 
ATOM   4035 N N   . ARG C 3 70  ? 139.175 139.816 122.520 1.00 40.72 ? 52  ARG C N   1 
ATOM   4036 C CA  . ARG C 3 70  ? 138.037 139.451 123.347 1.00 37.07 ? 52  ARG C CA  1 
ATOM   4037 C C   . ARG C 3 70  ? 136.760 140.020 122.745 1.00 36.57 ? 52  ARG C C   1 
ATOM   4038 O O   . ARG C 3 70  ? 136.791 140.928 121.911 1.00 42.48 ? 52  ARG C O   1 
ATOM   4039 C CB  . ARG C 3 70  ? 138.215 139.967 124.779 1.00 35.18 ? 52  ARG C CB  1 
ATOM   4040 C CG  . ARG C 3 70  ? 138.986 139.025 125.687 1.00 37.24 ? 52  ARG C CG  1 
ATOM   4041 C CD  . ARG C 3 70  ? 139.546 139.743 126.905 1.00 39.05 ? 52  ARG C CD  1 
ATOM   4042 N NE  . ARG C 3 70  ? 140.771 140.477 126.593 1.00 39.50 ? 52  ARG C NE  1 
ATOM   4043 C CZ  . ARG C 3 70  ? 142.011 140.054 126.817 1.00 35.27 ? 52  ARG C CZ  1 
ATOM   4044 N NH1 . ARG C 3 70  ? 142.264 138.859 127.330 1.00 38.88 ? 52  ARG C NH1 1 
ATOM   4045 N NH2 . ARG C 3 70  ? 143.030 140.852 126.510 1.00 31.30 ? 52  ARG C NH2 1 
ATOM   4046 N N   . GLY C 3 71  ? 135.631 139.475 123.187 1.00 40.03 ? 53  GLY C N   1 
ATOM   4047 C CA  . GLY C 3 71  ? 134.330 139.891 122.699 1.00 39.88 ? 53  GLY C CA  1 
ATOM   4048 C C   . GLY C 3 71  ? 133.379 138.724 122.542 1.00 36.77 ? 53  GLY C C   1 
ATOM   4049 O O   . GLY C 3 71  ? 132.158 138.895 122.600 1.00 33.01 ? 53  GLY C O   1 
ATOM   4050 N N   . HIS C 3 72  ? 133.930 137.533 122.337 1.00 38.85 ? 54  HIS C N   1 
ATOM   4051 C CA  . HIS C 3 72  ? 133.147 136.311 122.330 1.00 42.51 ? 54  HIS C CA  1 
ATOM   4052 C C   . HIS C 3 72  ? 132.945 135.830 123.760 1.00 49.79 ? 54  HIS C C   1 
ATOM   4053 O O   . HIS C 3 72  ? 133.850 135.908 124.595 1.00 46.86 ? 54  HIS C O   1 
ATOM   4054 C CB  . HIS C 3 72  ? 133.842 135.224 121.506 1.00 46.65 ? 54  HIS C CB  1 
ATOM   4055 C CG  . HIS C 3 72  ? 133.528 135.275 120.041 1.00 46.23 ? 54  HIS C CG  1 
ATOM   4056 N ND1 . HIS C 3 72  ? 132.244 135.399 119.555 1.00 49.06 ? 54  HIS C ND1 1 
ATOM   4057 C CD2 . HIS C 3 72  ? 134.336 135.229 118.956 1.00 35.52 ? 54  HIS C CD2 1 
ATOM   4058 C CE1 . HIS C 3 72  ? 132.275 135.419 118.235 1.00 41.91 ? 54  HIS C CE1 1 
ATOM   4059 N NE2 . HIS C 3 72  ? 133.532 135.319 117.846 1.00 33.10 ? 54  HIS C NE2 1 
ATOM   4060 N N   . LEU C 3 73  ? 131.736 135.340 124.035 1.00 55.56 ? 55  LEU C N   1 
ATOM   4061 C CA  . LEU C 3 73  ? 131.362 134.829 125.350 1.00 50.16 ? 55  LEU C CA  1 
ATOM   4062 C C   . LEU C 3 73  ? 131.152 133.320 125.332 1.00 50.01 ? 55  LEU C C   1 
ATOM   4063 O O   . LEU C 3 73  ? 130.497 132.778 126.228 1.00 53.85 ? 55  LEU C O   1 
ATOM   4064 C CB  . LEU C 3 73  ? 130.096 135.534 125.843 1.00 47.44 ? 55  LEU C CB  1 
ATOM   4065 C CG  . LEU C 3 73  ? 130.162 137.056 126.012 1.00 49.92 ? 55  LEU C CG  1 
ATOM   4066 C CD1 . LEU C 3 73  ? 128.821 137.576 126.485 1.00 50.04 ? 55  LEU C CD1 1 
ATOM   4067 C CD2 . LEU C 3 73  ? 131.257 137.468 126.986 1.00 49.39 ? 55  LEU C CD2 1 
ATOM   4068 N N   . ALA C 3 74  ? 131.699 132.628 124.338 1.00 48.23 ? 56  ALA C N   1 
ATOM   4069 C CA  . ALA C 3 74  ? 131.449 131.207 124.149 1.00 50.30 ? 56  ALA C CA  1 
ATOM   4070 C C   . ALA C 3 74  ? 132.618 130.612 123.372 1.00 51.40 ? 56  ALA C C   1 
ATOM   4071 O O   . ALA C 3 74  ? 133.568 131.315 123.015 1.00 53.40 ? 56  ALA C O   1 
ATOM   4072 C CB  . ALA C 3 74  ? 130.113 130.997 123.433 1.00 50.09 ? 56  ALA C CB  1 
ATOM   4073 N N   . LYS C 3 75  ? 132.541 129.314 123.097 1.00 47.82 ? 57  LYS C N   1 
ATOM   4074 C CA  . LYS C 3 75  ? 133.588 128.643 122.341 1.00 47.62 ? 57  LYS C CA  1 
ATOM   4075 C C   . LYS C 3 75  ? 133.695 129.220 120.936 1.00 51.12 ? 57  LYS C C   1 
ATOM   4076 O O   . LYS C 3 75  ? 132.703 129.644 120.340 1.00 52.55 ? 57  LYS C O   1 
ATOM   4077 C CB  . LYS C 3 75  ? 133.310 127.145 122.244 1.00 47.98 ? 57  LYS C CB  1 
ATOM   4078 C CG  . LYS C 3 75  ? 133.136 126.436 123.573 1.00 50.88 ? 57  LYS C CG  1 
ATOM   4079 C CD  . LYS C 3 75  ? 132.667 124.998 123.383 1.00 54.87 ? 57  LYS C CD  1 
ATOM   4080 C CE  . LYS C 3 75  ? 131.168 124.906 123.108 1.00 52.22 ? 57  LYS C CE  1 
ATOM   4081 N NZ  . LYS C 3 75  ? 130.380 124.850 124.364 1.00 50.85 ? 57  LYS C NZ  1 
ATOM   4082 N N   . ILE C 3 76  ? 134.920 129.228 120.411 1.00 43.94 ? 58  ILE C N   1 
ATOM   4083 C CA  . ILE C 3 76  ? 135.200 129.659 119.046 1.00 41.01 ? 58  ILE C CA  1 
ATOM   4084 C C   . ILE C 3 76  ? 135.532 128.416 118.236 1.00 48.08 ? 58  ILE C C   1 
ATOM   4085 O O   . ILE C 3 76  ? 136.484 127.695 118.558 1.00 51.19 ? 58  ILE C O   1 
ATOM   4086 C CB  . ILE C 3 76  ? 136.366 130.659 119.003 1.00 37.06 ? 58  ILE C CB  1 
ATOM   4087 C CG1 . ILE C 3 76  ? 135.946 131.985 119.638 1.00 40.57 ? 58  ILE C CG1 1 
ATOM   4088 C CG2 . ILE C 3 76  ? 136.809 130.869 117.536 1.00 37.73 ? 58  ILE C CG2 1 
ATOM   4089 C CD1 . ILE C 3 76  ? 137.091 132.969 119.841 1.00 44.82 ? 58  ILE C CD1 1 
ATOM   4090 N N   . TYR C 3 77  ? 134.776 128.186 117.168 1.00 44.94 ? 59  TYR C N   1 
ATOM   4091 C CA  . TYR C 3 77  ? 134.934 127.000 116.338 1.00 42.42 ? 59  TYR C CA  1 
ATOM   4092 C C   . TYR C 3 77  ? 135.776 127.212 115.092 1.00 44.27 ? 59  TYR C C   1 
ATOM   4093 O O   . TYR C 3 77  ? 136.557 126.323 114.746 1.00 49.88 ? 59  TYR C O   1 
ATOM   4094 C CB  . TYR C 3 77  ? 133.565 126.455 115.908 1.00 45.15 ? 59  TYR C CB  1 
ATOM   4095 C CG  . TYR C 3 77  ? 132.705 125.804 116.982 1.00 46.55 ? 59  TYR C CG  1 
ATOM   4096 C CD1 . TYR C 3 77  ? 132.887 126.051 118.341 1.00 45.89 ? 59  TYR C CD1 1 
ATOM   4097 C CD2 . TYR C 3 77  ? 131.693 124.929 116.613 1.00 45.94 ? 59  TYR C CD2 1 
ATOM   4098 C CE1 . TYR C 3 77  ? 132.087 125.436 119.289 1.00 45.44 ? 59  TYR C CE1 1 
ATOM   4099 C CE2 . TYR C 3 77  ? 130.888 124.321 117.553 1.00 48.19 ? 59  TYR C CE2 1 
ATOM   4100 C CZ  . TYR C 3 77  ? 131.090 124.585 118.892 1.00 52.40 ? 59  TYR C CZ  1 
ATOM   4101 O OH  . TYR C 3 77  ? 130.315 123.990 119.859 1.00 58.32 ? 59  TYR C OH  1 
ATOM   4102 N N   . ALA C 3 78  ? 135.652 128.351 114.415 1.00 31.38 ? 60  ALA C N   1 
ATOM   4103 C CA  . ALA C 3 78  ? 136.310 128.522 113.127 1.00 30.59 ? 60  ALA C CA  1 
ATOM   4104 C C   . ALA C 3 78  ? 136.664 129.985 112.915 1.00 36.47 ? 60  ALA C C   1 
ATOM   4105 O O   . ALA C 3 78  ? 136.117 130.880 113.563 1.00 38.93 ? 60  ALA C O   1 
ATOM   4106 C CB  . ALA C 3 78  ? 135.423 128.014 111.989 1.00 31.62 ? 60  ALA C CB  1 
ATOM   4107 N N   . MET C 3 79  ? 137.603 130.207 111.998 1.00 26.94 ? 61  MET C N   1 
ATOM   4108 C CA  . MET C 3 79  ? 138.047 131.545 111.638 1.00 20.70 ? 61  MET C CA  1 
ATOM   4109 C C   . MET C 3 79  ? 138.682 131.489 110.258 1.00 25.61 ? 61  MET C C   1 
ATOM   4110 O O   . MET C 3 79  ? 139.023 130.416 109.756 1.00 31.64 ? 61  MET C O   1 
ATOM   4111 C CB  . MET C 3 79  ? 139.033 132.113 112.667 1.00 18.61 ? 61  MET C CB  1 
ATOM   4112 C CG  . MET C 3 79  ? 140.319 131.311 112.842 1.00 24.46 ? 61  MET C CG  1 
ATOM   4113 S SD  . MET C 3 79  ? 141.641 131.751 111.700 1.00 34.10 ? 61  MET C SD  1 
ATOM   4114 C CE  . MET C 3 79  ? 142.388 133.111 112.575 1.00 22.33 ? 61  MET C CE  1 
ATOM   4115 N N   . HIS C 3 80  ? 138.845 132.664 109.653 1.00 25.75 ? 62  HIS C N   1 
ATOM   4116 C CA  . HIS C 3 80  ? 139.499 132.772 108.350 1.00 22.70 ? 62  HIS C CA  1 
ATOM   4117 C C   . HIS C 3 80  ? 140.093 134.162 108.202 1.00 23.12 ? 62  HIS C C   1 
ATOM   4118 O O   . HIS C 3 80  ? 139.380 135.158 108.347 1.00 26.76 ? 62  HIS C O   1 
ATOM   4119 C CB  . HIS C 3 80  ? 138.518 132.487 107.217 1.00 20.08 ? 62  HIS C CB  1 
ATOM   4120 C CG  . HIS C 3 80  ? 139.176 132.037 105.952 1.00 22.09 ? 62  HIS C CG  1 
ATOM   4121 N ND1 . HIS C 3 80  ? 139.369 132.877 104.878 1.00 28.90 ? 62  HIS C ND1 1 
ATOM   4122 C CD2 . HIS C 3 80  ? 139.697 130.841 105.591 1.00 19.67 ? 62  HIS C CD2 1 
ATOM   4123 C CE1 . HIS C 3 80  ? 139.975 132.218 103.907 1.00 18.93 ? 62  HIS C CE1 1 
ATOM   4124 N NE2 . HIS C 3 80  ? 140.185 130.980 104.314 1.00 20.35 ? 62  HIS C NE2 1 
ATOM   4125 N N   . TRP C 3 81  ? 141.389 134.226 107.912 1.00 27.92 ? 63  TRP C N   1 
ATOM   4126 C CA  . TRP C 3 81  ? 142.048 135.498 107.649 1.00 20.16 ? 63  TRP C CA  1 
ATOM   4127 C C   . TRP C 3 81  ? 141.504 136.137 106.378 1.00 20.73 ? 63  TRP C C   1 
ATOM   4128 O O   . TRP C 3 81  ? 141.146 135.448 105.420 1.00 30.98 ? 63  TRP C O   1 
ATOM   4129 C CB  . TRP C 3 81  ? 143.555 135.297 107.501 1.00 17.71 ? 63  TRP C CB  1 
ATOM   4130 C CG  . TRP C 3 81  ? 144.328 135.399 108.772 1.00 18.52 ? 63  TRP C CG  1 
ATOM   4131 C CD1 . TRP C 3 81  ? 144.981 134.391 109.414 1.00 20.63 ? 63  TRP C CD1 1 
ATOM   4132 C CD2 . TRP C 3 81  ? 144.548 136.579 109.550 1.00 17.66 ? 63  TRP C CD2 1 
ATOM   4133 N NE1 . TRP C 3 81  ? 145.590 134.868 110.546 1.00 26.65 ? 63  TRP C NE1 1 
ATOM   4134 C CE2 . TRP C 3 81  ? 145.339 136.210 110.653 1.00 19.83 ? 63  TRP C CE2 1 
ATOM   4135 C CE3 . TRP C 3 81  ? 144.151 137.911 109.422 1.00 26.23 ? 63  TRP C CE3 1 
ATOM   4136 C CZ2 . TRP C 3 81  ? 145.739 137.123 111.622 1.00 20.52 ? 63  TRP C CZ2 1 
ATOM   4137 C CZ3 . TRP C 3 81  ? 144.548 138.814 110.384 1.00 18.83 ? 63  TRP C CZ3 1 
ATOM   4138 C CH2 . TRP C 3 81  ? 145.334 138.418 111.470 1.00 21.98 ? 63  TRP C CH2 1 
ATOM   4139 N N   . GLY C 3 82  ? 141.451 137.465 106.368 1.00 20.13 ? 64  GLY C N   1 
ATOM   4140 C CA  . GLY C 3 82  ? 141.160 138.177 105.144 1.00 24.14 ? 64  GLY C CA  1 
ATOM   4141 C C   . GLY C 3 82  ? 142.359 138.224 104.218 1.00 33.36 ? 64  GLY C C   1 
ATOM   4142 O O   . GLY C 3 82  ? 143.486 137.897 104.589 1.00 37.67 ? 64  GLY C O   1 
ATOM   4143 N N   . THR C 3 83  ? 142.108 138.644 102.977 1.00 35.58 ? 65  THR C N   1 
ATOM   4144 C CA  . THR C 3 83  ? 143.176 138.723 101.987 1.00 29.78 ? 65  THR C CA  1 
ATOM   4145 C C   . THR C 3 83  ? 144.112 139.897 102.243 1.00 31.52 ? 65  THR C C   1 
ATOM   4146 O O   . THR C 3 83  ? 145.298 139.810 101.908 1.00 30.96 ? 65  THR C O   1 
ATOM   4147 C CB  . THR C 3 83  ? 142.570 138.810 100.578 1.00 28.39 ? 65  THR C CB  1 
ATOM   4148 O OG1 . THR C 3 83  ? 142.210 137.496 100.139 1.00 35.91 ? 65  THR C OG1 1 
ATOM   4149 C CG2 . THR C 3 83  ? 143.550 139.401 99.552  1.00 31.31 ? 65  THR C CG2 1 
ATOM   4150 N N   . ASP C 3 84  ? 143.619 140.980 102.839 1.00 37.81 ? 66  ASP C N   1 
ATOM   4151 C CA  . ASP C 3 84  ? 144.445 142.145 103.133 1.00 35.24 ? 66  ASP C CA  1 
ATOM   4152 C C   . ASP C 3 84  ? 145.285 141.977 104.396 1.00 32.25 ? 66  ASP C C   1 
ATOM   4153 O O   . ASP C 3 84  ? 145.898 142.950 104.845 1.00 35.59 ? 66  ASP C O   1 
ATOM   4154 C CB  . ASP C 3 84  ? 143.579 143.408 103.253 1.00 34.37 ? 66  ASP C CB  1 
ATOM   4155 C CG  . ASP C 3 84  ? 142.474 143.276 104.284 1.00 38.01 ? 66  ASP C CG  1 
ATOM   4156 O OD1 . ASP C 3 84  ? 142.413 142.238 104.973 1.00 39.66 ? 66  ASP C OD1 1 
ATOM   4157 O OD2 . ASP C 3 84  ? 141.666 144.219 104.406 1.00 33.93 ? 66  ASP C OD2 1 
ATOM   4158 N N   . SER C 3 85  ? 145.316 140.780 104.986 1.00 25.08 ? 67  SER C N   1 
ATOM   4159 C CA  . SER C 3 85  ? 146.209 140.431 106.088 1.00 21.33 ? 67  SER C CA  1 
ATOM   4160 C C   . SER C 3 85  ? 145.937 141.231 107.358 1.00 23.73 ? 67  SER C C   1 
ATOM   4161 O O   . SER C 3 85  ? 146.766 141.232 108.271 1.00 33.33 ? 67  SER C O   1 
ATOM   4162 C CB  . SER C 3 85  ? 147.678 140.597 105.674 1.00 34.71 ? 67  SER C CB  1 
ATOM   4163 O OG  . SER C 3 85  ? 148.041 139.617 104.719 1.00 43.93 ? 67  SER C OG  1 
ATOM   4164 N N   . ARG C 3 86  ? 144.785 141.902 107.445 1.00 26.78 ? 68  ARG C N   1 
ATOM   4165 C CA  . ARG C 3 86  ? 144.448 142.735 108.594 1.00 24.65 ? 68  ARG C CA  1 
ATOM   4166 C C   . ARG C 3 86  ? 143.106 142.331 109.187 1.00 26.34 ? 68  ARG C C   1 
ATOM   4167 O O   . ARG C 3 86  ? 142.949 142.298 110.411 1.00 33.69 ? 68  ARG C O   1 
ATOM   4168 C CB  . ARG C 3 86  ? 144.421 144.208 108.187 1.00 24.31 ? 68  ARG C CB  1 
ATOM   4169 C CG  . ARG C 3 86  ? 144.021 145.148 109.306 1.00 26.97 ? 68  ARG C CG  1 
ATOM   4170 C CD  . ARG C 3 86  ? 144.428 146.576 109.002 1.00 32.22 ? 68  ARG C CD  1 
ATOM   4171 N NE  . ARG C 3 86  ? 144.095 147.489 110.089 1.00 30.14 ? 68  ARG C NE  1 
ATOM   4172 C CZ  . ARG C 3 86  ? 144.493 148.752 110.168 1.00 30.42 ? 68  ARG C CZ  1 
ATOM   4173 N NH1 . ARG C 3 86  ? 145.243 149.307 109.227 1.00 32.68 ? 68  ARG C NH1 1 
ATOM   4174 N NH2 . ARG C 3 86  ? 144.129 149.481 111.218 1.00 26.06 ? 68  ARG C NH2 1 
ATOM   4175 N N   . LEU C 3 87  ? 142.138 142.020 108.331 1.00 23.28 ? 69  LEU C N   1 
ATOM   4176 C CA  . LEU C 3 87  ? 140.799 141.645 108.755 1.00 12.96 ? 69  LEU C CA  1 
ATOM   4177 C C   . LEU C 3 87  ? 140.683 140.132 108.866 1.00 16.68 ? 69  LEU C C   1 
ATOM   4178 O O   . LEU C 3 87  ? 141.253 139.388 108.066 1.00 27.88 ? 69  LEU C O   1 
ATOM   4179 C CB  . LEU C 3 87  ? 139.749 142.158 107.770 1.00 15.02 ? 69  LEU C CB  1 
ATOM   4180 C CG  . LEU C 3 87  ? 139.539 143.666 107.667 1.00 15.90 ? 69  LEU C CG  1 
ATOM   4181 C CD1 . LEU C 3 87  ? 138.714 143.976 106.432 1.00 22.45 ? 69  LEU C CD1 1 
ATOM   4182 C CD2 . LEU C 3 87  ? 138.865 144.208 108.909 1.00 22.09 ? 69  LEU C CD2 1 
ATOM   4183 N N   . LEU C 3 88  ? 139.934 139.685 109.871 1.00 20.65 ? 70  LEU C N   1 
ATOM   4184 C CA  . LEU C 3 88  ? 139.589 138.278 110.001 1.00 25.27 ? 70  LEU C CA  1 
ATOM   4185 C C   . LEU C 3 88  ? 138.186 138.174 110.574 1.00 25.81 ? 70  LEU C C   1 
ATOM   4186 O O   . LEU C 3 88  ? 137.674 139.110 111.192 1.00 39.71 ? 70  LEU C O   1 
ATOM   4187 C CB  . LEU C 3 88  ? 140.591 137.507 110.877 1.00 25.20 ? 70  LEU C CB  1 
ATOM   4188 C CG  . LEU C 3 88  ? 140.668 137.740 112.389 1.00 20.73 ? 70  LEU C CG  1 
ATOM   4189 C CD1 . LEU C 3 88  ? 141.363 136.569 113.046 1.00 26.58 ? 70  LEU C CD1 1 
ATOM   4190 C CD2 . LEU C 3 88  ? 141.410 139.013 112.705 1.00 25.84 ? 70  LEU C CD2 1 
ATOM   4191 N N   . VAL C 3 89  ? 137.572 137.016 110.354 1.00 18.46 ? 71  VAL C N   1 
ATOM   4192 C CA  . VAL C 3 89  ? 136.232 136.709 110.834 1.00 23.84 ? 71  VAL C CA  1 
ATOM   4193 C C   . VAL C 3 89  ? 136.322 135.434 111.655 1.00 31.95 ? 71  VAL C C   1 
ATOM   4194 O O   . VAL C 3 89  ? 137.148 134.563 111.365 1.00 43.82 ? 71  VAL C O   1 
ATOM   4195 C CB  . VAL C 3 89  ? 135.227 136.550 109.671 1.00 19.29 ? 71  VAL C CB  1 
ATOM   4196 C CG1 . VAL C 3 89  ? 135.624 135.402 108.743 1.00 24.50 ? 71  VAL C CG1 1 
ATOM   4197 C CG2 . VAL C 3 89  ? 133.825 136.347 110.202 1.00 27.59 ? 71  VAL C CG2 1 
ATOM   4198 N N   . SER C 3 90  ? 135.492 135.332 112.690 1.00 27.35 ? 72  SER C N   1 
ATOM   4199 C CA  . SER C 3 90  ? 135.471 134.168 113.561 1.00 22.49 ? 72  SER C CA  1 
ATOM   4200 C C   . SER C 3 90  ? 134.037 133.848 113.954 1.00 29.90 ? 72  SER C C   1 
ATOM   4201 O O   . SER C 3 90  ? 133.205 134.746 114.104 1.00 35.47 ? 72  SER C O   1 
ATOM   4202 C CB  . SER C 3 90  ? 136.313 134.398 114.815 1.00 26.15 ? 72  SER C CB  1 
ATOM   4203 O OG  . SER C 3 90  ? 135.526 134.941 115.857 1.00 39.13 ? 72  SER C OG  1 
ATOM   4204 N N   . ALA C 3 91  ? 133.765 132.556 114.132 1.00 32.66 ? 73  ALA C N   1 
ATOM   4205 C CA  . ALA C 3 91  ? 132.435 132.046 114.442 1.00 29.84 ? 73  ALA C CA  1 
ATOM   4206 C C   . ALA C 3 91  ? 132.474 131.324 115.779 1.00 36.48 ? 73  ALA C C   1 
ATOM   4207 O O   . ALA C 3 91  ? 133.422 130.583 116.058 1.00 41.57 ? 73  ALA C O   1 
ATOM   4208 C CB  . ALA C 3 91  ? 131.944 131.101 113.348 1.00 36.23 ? 73  ALA C CB  1 
ATOM   4209 N N   . SER C 3 92  ? 131.447 131.543 116.598 1.00 45.05 ? 74  SER C N   1 
ATOM   4210 C CA  . SER C 3 92  ? 131.362 130.999 117.945 1.00 47.01 ? 74  SER C CA  1 
ATOM   4211 C C   . SER C 3 92  ? 130.037 130.273 118.140 1.00 46.98 ? 74  SER C C   1 
ATOM   4212 O O   . SER C 3 92  ? 129.164 130.274 117.270 1.00 45.43 ? 74  SER C O   1 
ATOM   4213 C CB  . SER C 3 92  ? 131.515 132.109 118.990 1.00 45.20 ? 74  SER C CB  1 
ATOM   4214 O OG  . SER C 3 92  ? 131.077 131.675 120.264 1.00 49.99 ? 74  SER C OG  1 
ATOM   4215 N N   . GLN C 3 93  ? 129.896 129.647 119.313 1.00 50.54 ? 75  GLN C N   1 
ATOM   4216 C CA  . GLN C 3 93  ? 128.679 128.901 119.616 1.00 48.07 ? 75  GLN C CA  1 
ATOM   4217 C C   . GLN C 3 93  ? 127.556 129.834 120.059 1.00 50.78 ? 75  GLN C C   1 
ATOM   4218 O O   . GLN C 3 93  ? 126.380 129.467 119.964 1.00 53.74 ? 75  GLN C O   1 
ATOM   4219 C CB  . GLN C 3 93  ? 128.977 127.833 120.683 1.00 48.50 ? 75  GLN C CB  1 
ATOM   4220 C CG  . GLN C 3 93  ? 127.764 127.207 121.429 1.00 54.66 ? 75  GLN C CG  1 
ATOM   4221 C CD  . GLN C 3 93  ? 127.567 127.680 122.869 1.00 52.53 ? 75  GLN C CD  1 
ATOM   4222 O OE1 . GLN C 3 93  ? 128.390 128.392 123.431 1.00 45.85 ? 75  GLN C OE1 1 
ATOM   4223 N NE2 . GLN C 3 93  ? 126.455 127.277 123.470 1.00 56.30 ? 75  GLN C NE2 1 
ATOM   4224 N N   . ASP C 3 94  ? 127.880 131.054 120.499 1.00 45.23 ? 76  ASP C N   1 
ATOM   4225 C CA  . ASP C 3 94  ? 126.838 131.980 120.930 1.00 41.86 ? 76  ASP C CA  1 
ATOM   4226 C C   . ASP C 3 94  ? 125.933 132.437 119.790 1.00 44.02 ? 76  ASP C C   1 
ATOM   4227 O O   . ASP C 3 94  ? 124.879 133.019 120.064 1.00 47.11 ? 76  ASP C O   1 
ATOM   4228 C CB  . ASP C 3 94  ? 127.451 133.208 121.616 1.00 43.81 ? 76  ASP C CB  1 
ATOM   4229 C CG  . ASP C 3 94  ? 128.433 133.955 120.732 1.00 46.97 ? 76  ASP C CG  1 
ATOM   4230 O OD1 . ASP C 3 94  ? 128.700 133.498 119.603 1.00 47.50 ? 76  ASP C OD1 1 
ATOM   4231 O OD2 . ASP C 3 94  ? 128.936 135.010 121.171 1.00 46.21 ? 76  ASP C OD2 1 
ATOM   4232 N N   . GLY C 3 95  ? 126.306 132.190 118.539 1.00 45.72 ? 77  GLY C N   1 
ATOM   4233 C CA  . GLY C 3 95  ? 125.502 132.582 117.403 1.00 44.89 ? 77  GLY C CA  1 
ATOM   4234 C C   . GLY C 3 95  ? 125.849 133.921 116.794 1.00 46.14 ? 77  GLY C C   1 
ATOM   4235 O O   . GLY C 3 95  ? 125.034 134.458 116.035 1.00 48.56 ? 77  GLY C O   1 
ATOM   4236 N N   . LYS C 3 96  ? 127.015 134.480 117.110 1.00 44.15 ? 78  LYS C N   1 
ATOM   4237 C CA  . LYS C 3 96  ? 127.472 135.752 116.566 1.00 38.38 ? 78  LYS C CA  1 
ATOM   4238 C C   . LYS C 3 96  ? 128.690 135.506 115.691 1.00 33.18 ? 78  LYS C C   1 
ATOM   4239 O O   . LYS C 3 96  ? 129.627 134.814 116.104 1.00 33.16 ? 78  LYS C O   1 
ATOM   4240 C CB  . LYS C 3 96  ? 127.809 136.742 117.687 1.00 38.39 ? 78  LYS C CB  1 
ATOM   4241 C CG  . LYS C 3 96  ? 126.609 137.175 118.515 1.00 40.10 ? 78  LYS C CG  1 
ATOM   4242 C CD  . LYS C 3 96  ? 125.911 138.392 117.895 1.00 41.90 ? 78  LYS C CD  1 
ATOM   4243 C CE  . LYS C 3 96  ? 124.472 138.603 118.385 1.00 43.18 ? 78  LYS C CE  1 
ATOM   4244 N NZ  . LYS C 3 96  ? 123.606 137.385 118.382 1.00 39.29 ? 78  LYS C NZ  1 
ATOM   4245 N N   . LEU C 3 97  ? 128.664 136.061 114.482 1.00 34.19 ? 79  LEU C N   1 
ATOM   4246 C CA  . LEU C 3 97  ? 129.786 136.028 113.551 1.00 31.47 ? 79  LEU C CA  1 
ATOM   4247 C C   . LEU C 3 97  ? 130.287 137.456 113.399 1.00 28.89 ? 79  LEU C C   1 
ATOM   4248 O O   . LEU C 3 97  ? 129.620 138.282 112.767 1.00 32.95 ? 79  LEU C O   1 
ATOM   4249 C CB  . LEU C 3 97  ? 129.360 135.444 112.202 1.00 29.77 ? 79  LEU C CB  1 
ATOM   4250 C CG  . LEU C 3 97  ? 130.429 135.285 111.121 1.00 28.77 ? 79  LEU C CG  1 
ATOM   4251 C CD1 . LEU C 3 97  ? 131.235 134.035 111.380 1.00 30.00 ? 79  LEU C CD1 1 
ATOM   4252 C CD2 . LEU C 3 97  ? 129.793 135.222 109.751 1.00 24.32 ? 79  LEU C CD2 1 
ATOM   4253 N N   . ILE C 3 98  ? 131.454 137.742 113.978 1.00 21.68 ? 80  ILE C N   1 
ATOM   4254 C CA  . ILE C 3 98  ? 131.946 139.105 114.140 1.00 28.59 ? 80  ILE C CA  1 
ATOM   4255 C C   . ILE C 3 98  ? 133.348 139.225 113.561 1.00 23.05 ? 80  ILE C C   1 
ATOM   4256 O O   . ILE C 3 98  ? 134.201 138.352 113.749 1.00 23.68 ? 80  ILE C O   1 
ATOM   4257 C CB  . ILE C 3 98  ? 131.889 139.542 115.628 1.00 31.05 ? 80  ILE C CB  1 
ATOM   4258 C CG1 . ILE C 3 98  ? 133.078 139.004 116.437 1.00 30.99 ? 80  ILE C CG1 1 
ATOM   4259 C CG2 . ILE C 3 98  ? 130.549 139.141 116.249 1.00 32.29 ? 80  ILE C CG2 1 
ATOM   4260 C CD1 . ILE C 3 98  ? 132.868 139.110 117.946 1.00 28.93 ? 80  ILE C CD1 1 
ATOM   4261 N N   . ILE C 3 99  ? 133.573 140.326 112.845 1.00 28.32 ? 81  ILE C N   1 
ATOM   4262 C CA  . ILE C 3 99  ? 134.790 140.569 112.076 1.00 30.27 ? 81  ILE C CA  1 
ATOM   4263 C C   . ILE C 3 99  ? 135.673 141.513 112.879 1.00 23.63 ? 81  ILE C C   1 
ATOM   4264 O O   . ILE C 3 99  ? 135.193 142.527 113.399 1.00 26.20 ? 81  ILE C O   1 
ATOM   4265 C CB  . ILE C 3 99  ? 134.474 141.162 110.689 1.00 23.80 ? 81  ILE C CB  1 
ATOM   4266 C CG1 . ILE C 3 99  ? 133.366 140.364 109.988 1.00 20.98 ? 81  ILE C CG1 1 
ATOM   4267 C CG2 . ILE C 3 99  ? 135.730 141.190 109.809 1.00 23.00 ? 81  ILE C CG2 1 
ATOM   4268 C CD1 . ILE C 3 99  ? 133.000 140.890 108.623 1.00 28.64 ? 81  ILE C CD1 1 
ATOM   4269 N N   . TRP C 3 100 ? 136.959 141.186 112.967 1.00 12.41 ? 82  TRP C N   1 
ATOM   4270 C CA  . TRP C 3 100 ? 137.933 141.961 113.719 1.00 21.11 ? 82  TRP C CA  1 
ATOM   4271 C C   . TRP C 3 100 ? 138.800 142.793 112.784 1.00 22.24 ? 82  TRP C C   1 
ATOM   4272 O O   . TRP C 3 100 ? 138.916 142.521 111.587 1.00 30.80 ? 82  TRP C O   1 
ATOM   4273 C CB  . TRP C 3 100 ? 138.825 141.052 114.562 1.00 25.22 ? 82  TRP C CB  1 
ATOM   4274 C CG  . TRP C 3 100 ? 138.113 139.984 115.296 1.00 28.73 ? 82  TRP C CG  1 
ATOM   4275 C CD1 . TRP C 3 100 ? 137.813 138.735 114.843 1.00 35.06 ? 82  TRP C CD1 1 
ATOM   4276 C CD2 . TRP C 3 100 ? 137.616 140.058 116.632 1.00 23.37 ? 82  TRP C CD2 1 
ATOM   4277 N NE1 . TRP C 3 100 ? 137.158 138.026 115.815 1.00 28.49 ? 82  TRP C NE1 1 
ATOM   4278 C CE2 . TRP C 3 100 ? 137.024 138.817 116.925 1.00 20.69 ? 82  TRP C CE2 1 
ATOM   4279 C CE3 . TRP C 3 100 ? 137.612 141.055 117.609 1.00 29.22 ? 82  TRP C CE3 1 
ATOM   4280 C CZ2 . TRP C 3 100 ? 136.438 138.546 118.151 1.00 28.25 ? 82  TRP C CZ2 1 
ATOM   4281 C CZ3 . TRP C 3 100 ? 137.030 140.784 118.824 1.00 27.88 ? 82  TRP C CZ3 1 
ATOM   4282 C CH2 . TRP C 3 100 ? 136.448 139.541 119.086 1.00 30.48 ? 82  TRP C CH2 1 
ATOM   4283 N N   . ASP C 3 101 ? 139.420 143.819 113.363 1.00 24.04 ? 83  ASP C N   1 
ATOM   4284 C CA  . ASP C 3 101 ? 140.504 144.568 112.741 1.00 25.87 ? 83  ASP C CA  1 
ATOM   4285 C C   . ASP C 3 101 ? 141.754 144.291 113.560 1.00 26.65 ? 83  ASP C C   1 
ATOM   4286 O O   . ASP C 3 101 ? 141.867 144.762 114.695 1.00 33.64 ? 83  ASP C O   1 
ATOM   4287 C CB  . ASP C 3 101 ? 140.188 146.064 112.700 1.00 30.16 ? 83  ASP C CB  1 
ATOM   4288 C CG  . ASP C 3 101 ? 141.315 146.885 112.116 1.00 29.62 ? 83  ASP C CG  1 
ATOM   4289 O OD1 . ASP C 3 101 ? 142.177 146.311 111.422 1.00 30.48 ? 83  ASP C OD1 1 
ATOM   4290 O OD2 . ASP C 3 101 ? 141.338 148.111 112.348 1.00 23.20 ? 83  ASP C OD2 1 
ATOM   4291 N N   . SER C 3 102 ? 142.685 143.525 112.987 1.00 20.40 ? 84  SER C N   1 
ATOM   4292 C CA  . SER C 3 102 ? 143.765 142.938 113.777 1.00 19.21 ? 84  SER C CA  1 
ATOM   4293 C C   . SER C 3 102 ? 144.672 144.000 114.385 1.00 35.70 ? 84  SER C C   1 
ATOM   4294 O O   . SER C 3 102 ? 145.024 143.920 115.567 1.00 38.85 ? 84  SER C O   1 
ATOM   4295 C CB  . SER C 3 102 ? 144.586 141.987 112.911 1.00 19.77 ? 84  SER C CB  1 
ATOM   4296 O OG  . SER C 3 102 ? 143.791 140.919 112.443 1.00 28.59 ? 84  SER C OG  1 
ATOM   4297 N N   . TYR C 3 103 ? 145.070 144.999 113.593 1.00 34.30 ? 85  TYR C N   1 
ATOM   4298 C CA  . TYR C 3 103 ? 146.098 145.930 114.050 1.00 27.39 ? 85  TYR C CA  1 
ATOM   4299 C C   . TYR C 3 103 ? 145.624 146.752 115.241 1.00 28.94 ? 85  TYR C C   1 
ATOM   4300 O O   . TYR C 3 103 ? 146.348 146.884 116.234 1.00 33.15 ? 85  TYR C O   1 
ATOM   4301 C CB  . TYR C 3 103 ? 146.525 146.854 112.907 1.00 27.44 ? 85  TYR C CB  1 
ATOM   4302 C CG  . TYR C 3 103 ? 147.227 146.197 111.726 1.00 21.29 ? 85  TYR C CG  1 
ATOM   4303 C CD1 . TYR C 3 103 ? 147.557 144.846 111.720 1.00 24.17 ? 85  TYR C CD1 1 
ATOM   4304 C CD2 . TYR C 3 103 ? 147.574 146.950 110.615 1.00 26.63 ? 85  TYR C CD2 1 
ATOM   4305 C CE1 . TYR C 3 103 ? 148.197 144.272 110.642 1.00 29.82 ? 85  TYR C CE1 1 
ATOM   4306 C CE2 . TYR C 3 103 ? 148.213 146.383 109.534 1.00 29.53 ? 85  TYR C CE2 1 
ATOM   4307 C CZ  . TYR C 3 103 ? 148.523 145.045 109.553 1.00 31.75 ? 85  TYR C CZ  1 
ATOM   4308 O OH  . TYR C 3 103 ? 149.161 144.478 108.475 1.00 34.12 ? 85  TYR C OH  1 
ATOM   4309 N N   . THR C 3 104 ? 144.389 147.262 115.177 1.00 22.25 ? 86  THR C N   1 
ATOM   4310 C CA  . THR C 3 104 ? 143.867 148.123 116.268 1.00 28.56 ? 86  THR C CA  1 
ATOM   4311 C C   . THR C 3 104 ? 142.968 147.320 117.190 1.00 31.21 ? 86  THR C C   1 
ATOM   4312 O O   . THR C 3 104 ? 142.610 147.861 118.261 1.00 26.20 ? 86  THR C O   1 
ATOM   4313 C CB  . THR C 3 104 ? 143.159 149.333 115.660 1.00 28.09 ? 86  THR C CB  1 
ATOM   4314 O OG1 . THR C 3 104 ? 142.429 148.807 114.557 1.00 38.10 ? 86  THR C OG1 1 
ATOM   4315 C CG2 . THR C 3 104 ? 144.131 150.383 115.158 1.00 26.95 ? 86  THR C CG2 1 
ATOM   4316 N N   . THR C 3 105 ? 142.590 146.098 116.802 1.00 30.52 ? 87  THR C N   1 
ATOM   4317 C CA  . THR C 3 105 ? 141.802 145.202 117.649 1.00 30.28 ? 87  THR C CA  1 
ATOM   4318 C C   . THR C 3 105 ? 140.443 145.832 117.965 1.00 33.02 ? 87  THR C C   1 
ATOM   4319 O O   . THR C 3 105 ? 140.064 146.041 119.119 1.00 40.18 ? 87  THR C O   1 
ATOM   4320 C CB  . THR C 3 105 ? 142.582 144.838 118.919 1.00 34.93 ? 87  THR C CB  1 
ATOM   4321 O OG1 . THR C 3 105 ? 143.774 144.135 118.551 1.00 32.75 ? 87  THR C OG1 1 
ATOM   4322 C CG2 . THR C 3 105 ? 141.782 143.898 119.822 1.00 39.62 ? 87  THR C CG2 1 
ATOM   4323 N N   . ASN C 3 106 ? 139.729 146.199 116.903 1.00 28.53 ? 88  ASN C N   1 
ATOM   4324 C CA  . ASN C 3 106 ? 138.343 146.631 116.988 1.00 32.40 ? 88  ASN C CA  1 
ATOM   4325 C C   . ASN C 3 106 ? 137.432 145.524 116.471 1.00 29.82 ? 88  ASN C C   1 
ATOM   4326 O O   . ASN C 3 106 ? 137.862 144.401 116.203 1.00 31.15 ? 88  ASN C O   1 
ATOM   4327 C CB  . ASN C 3 106 ? 138.116 147.924 116.201 1.00 27.12 ? 88  ASN C CB  1 
ATOM   4328 C CG  . ASN C 3 106 ? 139.301 148.852 116.248 1.00 30.09 ? 88  ASN C CG  1 
ATOM   4329 O OD1 . ASN C 3 106 ? 140.176 148.797 115.392 1.00 37.21 ? 88  ASN C OD1 1 
ATOM   4330 N ND2 . ASN C 3 106 ? 139.333 149.719 117.250 1.00 29.14 ? 88  ASN C ND2 1 
ATOM   4331 N N   . LYS C 3 107 ? 136.150 145.851 116.346 1.00 27.18 ? 89  LYS C N   1 
ATOM   4332 C CA  . LYS C 3 107 ? 135.158 144.987 115.722 1.00 27.75 ? 89  LYS C CA  1 
ATOM   4333 C C   . LYS C 3 107 ? 134.501 145.761 114.592 1.00 38.68 ? 89  LYS C C   1 
ATOM   4334 O O   . LYS C 3 107 ? 133.916 146.824 114.822 1.00 50.11 ? 89  LYS C O   1 
ATOM   4335 C CB  . LYS C 3 107 ? 134.112 144.528 116.737 1.00 34.04 ? 89  LYS C CB  1 
ATOM   4336 C CG  . LYS C 3 107 ? 134.688 143.743 117.897 1.00 34.67 ? 89  LYS C CG  1 
ATOM   4337 C CD  . LYS C 3 107 ? 133.591 143.262 118.835 1.00 37.57 ? 89  LYS C CD  1 
ATOM   4338 C CE  . LYS C 3 107 ? 134.140 142.537 120.056 1.00 37.91 ? 89  LYS C CE  1 
ATOM   4339 N NZ  . LYS C 3 107 ? 135.191 143.307 120.779 1.00 42.87 ? 89  LYS C NZ  1 
ATOM   4340 N N   . VAL C 3 108 ? 134.598 145.231 113.380 1.00 23.71 ? 90  VAL C N   1 
ATOM   4341 C CA  . VAL C 3 108 ? 134.074 145.896 112.194 1.00 19.19 ? 90  VAL C CA  1 
ATOM   4342 C C   . VAL C 3 108 ? 132.588 145.622 112.022 1.00 24.30 ? 90  VAL C C   1 
ATOM   4343 O O   . VAL C 3 108 ? 131.815 146.530 111.718 1.00 31.90 ? 90  VAL C O   1 
ATOM   4344 C CB  . VAL C 3 108 ? 134.876 145.466 110.945 1.00 21.08 ? 90  VAL C CB  1 
ATOM   4345 C CG1 . VAL C 3 108 ? 134.544 146.354 109.757 1.00 23.83 ? 90  VAL C CG1 1 
ATOM   4346 C CG2 . VAL C 3 108 ? 136.366 145.508 111.235 1.00 19.57 ? 90  VAL C CG2 1 
ATOM   4347 N N   . HIS C 3 109 ? 132.172 144.373 112.216 1.00 23.67 ? 91  HIS C N   1 
ATOM   4348 C CA  . HIS C 3 109 ? 130.779 143.980 112.069 1.00 24.11 ? 91  HIS C CA  1 
ATOM   4349 C C   . HIS C 3 109 ? 130.431 142.948 113.128 1.00 21.28 ? 91  HIS C C   1 
ATOM   4350 O O   . HIS C 3 109 ? 131.302 142.250 113.649 1.00 26.67 ? 91  HIS C O   1 
ATOM   4351 C CB  . HIS C 3 109 ? 130.493 143.396 110.680 1.00 24.01 ? 91  HIS C CB  1 
ATOM   4352 C CG  . HIS C 3 109 ? 130.581 144.395 109.570 1.00 11.64 ? 91  HIS C CG  1 
ATOM   4353 N ND1 . HIS C 3 109 ? 131.664 144.472 108.723 1.00 15.61 ? 91  HIS C ND1 1 
ATOM   4354 C CD2 . HIS C 3 109 ? 129.719 145.357 109.166 1.00 12.40 ? 91  HIS C CD2 1 
ATOM   4355 C CE1 . HIS C 3 109 ? 131.465 145.437 107.843 1.00 21.97 ? 91  HIS C CE1 1 
ATOM   4356 N NE2 . HIS C 3 109 ? 130.292 145.991 108.091 1.00 22.93 ? 91  HIS C NE2 1 
ATOM   4357 N N   . ALA C 3 110 ? 129.141 142.868 113.441 1.00 21.68 ? 92  ALA C N   1 
ATOM   4358 C CA  . ALA C 3 110 ? 128.589 141.834 114.303 1.00 23.32 ? 92  ALA C CA  1 
ATOM   4359 C C   . ALA C 3 110 ? 127.297 141.346 113.672 1.00 28.54 ? 92  ALA C C   1 
ATOM   4360 O O   . ALA C 3 110 ? 126.319 142.096 113.596 1.00 32.55 ? 92  ALA C O   1 
ATOM   4361 C CB  . ALA C 3 110 ? 128.334 142.359 115.718 1.00 30.53 ? 92  ALA C CB  1 
ATOM   4362 N N   . ILE C 3 111 ? 127.295 140.095 113.227 1.00 29.73 ? 93  ILE C N   1 
ATOM   4363 C CA  . ILE C 3 111 ? 126.231 139.536 112.404 1.00 30.85 ? 93  ILE C CA  1 
ATOM   4364 C C   . ILE C 3 111 ? 125.445 138.548 113.261 1.00 34.67 ? 93  ILE C C   1 
ATOM   4365 O O   . ILE C 3 111 ? 125.982 137.502 113.635 1.00 35.35 ? 93  ILE C O   1 
ATOM   4366 C CB  . ILE C 3 111 ? 126.776 138.843 111.142 1.00 29.19 ? 93  ILE C CB  1 
ATOM   4367 C CG1 . ILE C 3 111 ? 127.661 139.799 110.321 1.00 28.16 ? 93  ILE C CG1 1 
ATOM   4368 C CG2 . ILE C 3 111 ? 125.618 138.308 110.298 1.00 34.20 ? 93  ILE C CG2 1 
ATOM   4369 C CD1 . ILE C 3 111 ? 128.498 139.122 109.261 1.00 30.35 ? 93  ILE C CD1 1 
ATOM   4370 N N   . PRO C 3 112 ? 124.164 138.813 113.608 1.00 41.99 ? 94  PRO C N   1 
ATOM   4371 C CA  . PRO C 3 112 ? 123.412 137.802 114.364 1.00 38.14 ? 94  PRO C CA  1 
ATOM   4372 C C   . PRO C 3 112 ? 123.002 136.634 113.485 1.00 42.48 ? 94  PRO C C   1 
ATOM   4373 O O   . PRO C 3 112 ? 122.485 136.834 112.381 1.00 42.14 ? 94  PRO C O   1 
ATOM   4374 C CB  . PRO C 3 112 ? 122.192 138.572 114.894 1.00 38.42 ? 94  PRO C CB  1 
ATOM   4375 C CG  . PRO C 3 112 ? 122.296 139.965 114.356 1.00 39.94 ? 94  PRO C CG  1 
ATOM   4376 C CD  . PRO C 3 112 ? 123.303 139.959 113.266 1.00 44.23 ? 94  PRO C CD  1 
ATOM   4377 N N   . LEU C 3 113 ? 123.222 135.415 113.969 1.00 50.10 ? 95  LEU C N   1 
ATOM   4378 C CA  . LEU C 3 113 ? 122.987 134.207 113.194 1.00 46.65 ? 95  LEU C CA  1 
ATOM   4379 C C   . LEU C 3 113 ? 121.676 133.553 113.615 1.00 46.68 ? 95  LEU C C   1 
ATOM   4380 O O   . LEU C 3 113 ? 121.331 133.498 114.797 1.00 41.11 ? 95  LEU C O   1 
ATOM   4381 C CB  . LEU C 3 113 ? 124.141 133.222 113.379 1.00 40.69 ? 95  LEU C CB  1 
ATOM   4382 C CG  . LEU C 3 113 ? 125.533 133.760 113.031 1.00 35.34 ? 95  LEU C CG  1 
ATOM   4383 C CD1 . LEU C 3 113 ? 126.632 132.816 113.489 1.00 41.13 ? 95  LEU C CD1 1 
ATOM   4384 C CD2 . LEU C 3 113 ? 125.651 134.018 111.544 1.00 34.82 ? 95  LEU C CD2 1 
ATOM   4385 N N   . ARG C 3 114 ? 120.945 133.046 112.620 1.00 52.34 ? 96  ARG C N   1 
ATOM   4386 C CA  . ARG C 3 114 ? 119.665 132.408 112.906 1.00 57.42 ? 96  ARG C CA  1 
ATOM   4387 C C   . ARG C 3 114 ? 119.870 131.122 113.699 1.00 55.31 ? 96  ARG C C   1 
ATOM   4388 O O   . ARG C 3 114 ? 119.104 130.833 114.626 1.00 55.47 ? 96  ARG C O   1 
ATOM   4389 C CB  . ARG C 3 114 ? 118.905 132.170 111.589 1.00 52.86 ? 96  ARG C CB  1 
ATOM   4390 C CG  . ARG C 3 114 ? 117.701 131.188 111.586 1.00 51.68 ? 96  ARG C CG  1 
ATOM   4391 C CD  . ARG C 3 114 ? 117.564 130.509 110.231 1.00 54.40 ? 96  ARG C CD  1 
ATOM   4392 N NE  . ARG C 3 114 ? 118.490 129.394 110.070 1.00 55.77 ? 96  ARG C NE  1 
ATOM   4393 C CZ  . ARG C 3 114 ? 118.589 128.639 108.983 1.00 55.71 ? 96  ARG C CZ  1 
ATOM   4394 N NH1 . ARG C 3 114 ? 117.803 128.821 107.932 1.00 54.93 ? 96  ARG C NH1 1 
ATOM   4395 N NH2 . ARG C 3 114 ? 119.503 127.674 108.947 1.00 54.04 ? 96  ARG C NH2 1 
ATOM   4396 N N   . SER C 3 115 ? 120.896 130.347 113.358 1.00 54.12 ? 97  SER C N   1 
ATOM   4397 C CA  . SER C 3 115 ? 121.198 129.086 114.026 1.00 55.22 ? 97  SER C CA  1 
ATOM   4398 C C   . SER C 3 115 ? 122.420 129.262 114.916 1.00 48.92 ? 97  SER C C   1 
ATOM   4399 O O   . SER C 3 115 ? 123.440 129.801 114.476 1.00 51.72 ? 97  SER C O   1 
ATOM   4400 C CB  . SER C 3 115 ? 121.452 127.974 113.009 1.00 57.16 ? 97  SER C CB  1 
ATOM   4401 O OG  . SER C 3 115 ? 122.732 128.113 112.423 1.00 59.27 ? 97  SER C OG  1 
ATOM   4402 N N   . SER C 3 116 ? 122.312 128.809 116.165 1.00 49.71 ? 98  SER C N   1 
ATOM   4403 C CA  . SER C 3 116 ? 123.442 128.914 117.081 1.00 54.89 ? 98  SER C CA  1 
ATOM   4404 C C   . SER C 3 116 ? 124.518 127.868 116.796 1.00 55.90 ? 98  SER C C   1 
ATOM   4405 O O   . SER C 3 116 ? 125.640 127.992 117.301 1.00 49.98 ? 98  SER C O   1 
ATOM   4406 C CB  . SER C 3 116 ? 122.952 128.791 118.523 1.00 57.16 ? 98  SER C CB  1 
ATOM   4407 O OG  . SER C 3 116 ? 121.689 129.415 118.680 1.00 60.13 ? 98  SER C OG  1 
ATOM   4408 N N   . TRP C 3 117 ? 124.210 126.844 115.996 1.00 60.45 ? 99  TRP C N   1 
ATOM   4409 C CA  . TRP C 3 117 ? 125.161 125.776 115.685 1.00 54.36 ? 99  TRP C CA  1 
ATOM   4410 C C   . TRP C 3 117 ? 125.923 126.151 114.424 1.00 53.96 ? 99  TRP C C   1 
ATOM   4411 O O   . TRP C 3 117 ? 125.435 125.966 113.309 1.00 49.87 ? 99  TRP C O   1 
ATOM   4412 C CB  . TRP C 3 117 ? 124.434 124.448 115.523 1.00 54.52 ? 99  TRP C CB  1 
ATOM   4413 C CG  . TRP C 3 117 ? 123.413 124.241 116.586 1.00 57.44 ? 99  TRP C CG  1 
ATOM   4414 C CD1 . TRP C 3 117 ? 122.067 124.116 116.421 1.00 53.24 ? 99  TRP C CD1 1 
ATOM   4415 C CD2 . TRP C 3 117 ? 123.655 124.171 117.993 1.00 59.52 ? 99  TRP C CD2 1 
ATOM   4416 N NE1 . TRP C 3 117 ? 121.455 123.964 117.641 1.00 53.30 ? 99  TRP C NE1 1 
ATOM   4417 C CE2 . TRP C 3 117 ? 122.410 123.993 118.622 1.00 57.07 ? 99  TRP C CE2 1 
ATOM   4418 C CE3 . TRP C 3 117 ? 124.806 124.237 118.782 1.00 56.74 ? 99  TRP C CE3 1 
ATOM   4419 C CZ2 . TRP C 3 117 ? 122.284 123.880 120.001 1.00 59.88 ? 99  TRP C CZ2 1 
ATOM   4420 C CZ3 . TRP C 3 117 ? 124.678 124.123 120.149 1.00 56.24 ? 99  TRP C CZ3 1 
ATOM   4421 C CH2 . TRP C 3 117 ? 123.428 123.947 120.747 1.00 60.03 ? 99  TRP C CH2 1 
ATOM   4422 N N   . VAL C 3 118 ? 127.126 126.686 114.610 1.00 56.12 ? 100 VAL C N   1 
ATOM   4423 C CA  . VAL C 3 118 ? 127.984 127.152 113.529 1.00 50.09 ? 100 VAL C CA  1 
ATOM   4424 C C   . VAL C 3 118 ? 129.326 126.459 113.685 1.00 44.47 ? 100 VAL C C   1 
ATOM   4425 O O   . VAL C 3 118 ? 129.898 126.455 114.780 1.00 40.51 ? 100 VAL C O   1 
ATOM   4426 C CB  . VAL C 3 118 ? 128.148 128.684 113.557 1.00 44.41 ? 100 VAL C CB  1 
ATOM   4427 C CG1 . VAL C 3 118 ? 129.104 129.151 112.472 1.00 42.40 ? 100 VAL C CG1 1 
ATOM   4428 C CG2 . VAL C 3 118 ? 126.790 129.373 113.384 1.00 44.36 ? 100 VAL C CG2 1 
ATOM   4429 N N   . MET C 3 119 ? 129.829 125.887 112.589 1.00 46.34 ? 101 MET C N   1 
ATOM   4430 C CA  . MET C 3 119 ? 131.037 125.074 112.619 1.00 47.78 ? 101 MET C CA  1 
ATOM   4431 C C   . MET C 3 119 ? 132.076 125.459 111.572 1.00 44.36 ? 101 MET C C   1 
ATOM   4432 O O   . MET C 3 119 ? 133.220 125.001 111.671 1.00 41.12 ? 101 MET C O   1 
ATOM   4433 C CB  . MET C 3 119 ? 130.657 123.592 112.461 1.00 45.28 ? 101 MET C CB  1 
ATOM   4434 C CG  . MET C 3 119 ? 131.808 122.603 112.659 1.00 45.57 ? 101 MET C CG  1 
ATOM   4435 S SD  . MET C 3 119 ? 131.411 120.833 112.710 1.00 58.00 ? 101 MET C SD  1 
ATOM   4436 C CE  . MET C 3 119 ? 129.619 120.767 112.672 1.00 46.16 ? 101 MET C CE  1 
ATOM   4437 N N   . THR C 3 120 ? 131.733 126.304 110.603 1.00 33.71 ? 102 THR C N   1 
ATOM   4438 C CA  . THR C 3 120 ? 132.695 126.767 109.613 1.00 26.38 ? 102 THR C CA  1 
ATOM   4439 C C   . THR C 3 120 ? 132.368 128.198 109.220 1.00 35.57 ? 102 THR C C   1 
ATOM   4440 O O   . THR C 3 120 ? 131.213 128.625 109.297 1.00 34.65 ? 102 THR C O   1 
ATOM   4441 C CB  . THR C 3 120 ? 132.709 125.878 108.364 1.00 33.45 ? 102 THR C CB  1 
ATOM   4442 O OG1 . THR C 3 120 ? 133.564 126.462 107.374 1.00 41.53 ? 102 THR C OG1 1 
ATOM   4443 C CG2 . THR C 3 120 ? 131.305 125.697 107.788 1.00 33.59 ? 102 THR C CG2 1 
ATOM   4444 N N   . CYS C 3 121 ? 133.398 128.930 108.804 1.00 35.34 ? 103 CYS C N   1 
ATOM   4445 C CA  . CYS C 3 121 ? 133.250 130.282 108.289 1.00 27.37 ? 103 CYS C CA  1 
ATOM   4446 C C   . CYS C 3 121 ? 134.388 130.550 107.316 1.00 28.14 ? 103 CYS C C   1 
ATOM   4447 O O   . CYS C 3 121 ? 135.411 129.860 107.335 1.00 30.57 ? 103 CYS C O   1 
ATOM   4448 C CB  . CYS C 3 121 ? 133.258 131.323 109.411 1.00 14.93 ? 103 CYS C CB  1 
ATOM   4449 S SG  . CYS C 3 121 ? 134.907 131.758 109.983 1.00 21.79 ? 103 CYS C SG  1 
ATOM   4450 N N   . ALA C 3 122 ? 134.200 131.550 106.459 1.00 23.18 ? 104 ALA C N   1 
ATOM   4451 C CA  . ALA C 3 122 ? 135.204 131.881 105.460 1.00 20.13 ? 104 ALA C CA  1 
ATOM   4452 C C   . ALA C 3 122 ? 135.080 133.348 105.082 1.00 21.79 ? 104 ALA C C   1 
ATOM   4453 O O   . ALA C 3 122 ? 134.003 133.941 105.183 1.00 20.10 ? 104 ALA C O   1 
ATOM   4454 C CB  . ALA C 3 122 ? 135.066 130.999 104.217 1.00 21.79 ? 104 ALA C CB  1 
ATOM   4455 N N   . TYR C 3 123 ? 136.200 133.922 104.647 1.00 29.36 ? 105 TYR C N   1 
ATOM   4456 C CA  . TYR C 3 123 ? 136.282 135.306 104.201 1.00 19.09 ? 105 TYR C CA  1 
ATOM   4457 C C   . TYR C 3 123 ? 136.636 135.302 102.723 1.00 24.38 ? 105 TYR C C   1 
ATOM   4458 O O   . TYR C 3 123 ? 137.630 134.686 102.325 1.00 31.92 ? 105 TYR C O   1 
ATOM   4459 C CB  . TYR C 3 123 ? 137.335 136.074 105.002 1.00 15.43 ? 105 TYR C CB  1 
ATOM   4460 C CG  . TYR C 3 123 ? 137.026 137.540 105.197 1.00 21.49 ? 105 TYR C CG  1 
ATOM   4461 C CD1 . TYR C 3 123 ? 137.130 138.440 104.151 1.00 24.60 ? 105 TYR C CD1 1 
ATOM   4462 C CD2 . TYR C 3 123 ? 136.623 138.020 106.431 1.00 25.88 ? 105 TYR C CD2 1 
ATOM   4463 C CE1 . TYR C 3 123 ? 136.844 139.776 104.333 1.00 21.79 ? 105 TYR C CE1 1 
ATOM   4464 C CE2 . TYR C 3 123 ? 136.338 139.351 106.620 1.00 17.86 ? 105 TYR C CE2 1 
ATOM   4465 C CZ  . TYR C 3 123 ? 136.448 140.224 105.569 1.00 16.75 ? 105 TYR C CZ  1 
ATOM   4466 O OH  . TYR C 3 123 ? 136.163 141.555 105.753 1.00 23.92 ? 105 TYR C OH  1 
ATOM   4467 N N   . ALA C 3 124 ? 135.826 135.977 101.912 1.00 24.92 ? 106 ALA C N   1 
ATOM   4468 C CA  . ALA C 3 124 ? 136.016 135.924 100.473 1.00 21.33 ? 106 ALA C CA  1 
ATOM   4469 C C   . ALA C 3 124 ? 137.320 136.620 100.078 1.00 20.96 ? 106 ALA C C   1 
ATOM   4470 O O   . ALA C 3 124 ? 137.749 137.565 100.746 1.00 23.91 ? 106 ALA C O   1 
ATOM   4471 C CB  . ALA C 3 124 ? 134.845 136.582 99.755  1.00 22.24 ? 106 ALA C CB  1 
ATOM   4472 N N   . PRO C 3 125 ? 137.982 136.172 99.000  1.00 22.58 ? 107 PRO C N   1 
ATOM   4473 C CA  . PRO C 3 125 ? 139.220 136.855 98.594  1.00 22.53 ? 107 PRO C CA  1 
ATOM   4474 C C   . PRO C 3 125 ? 138.999 138.298 98.183  1.00 28.00 ? 107 PRO C C   1 
ATOM   4475 O O   . PRO C 3 125 ? 139.875 139.138 98.421  1.00 29.42 ? 107 PRO C O   1 
ATOM   4476 C CB  . PRO C 3 125 ? 139.734 136.009 97.419  1.00 21.59 ? 107 PRO C CB  1 
ATOM   4477 C CG  . PRO C 3 125 ? 138.868 134.807 97.361  1.00 21.78 ? 107 PRO C CG  1 
ATOM   4478 C CD  . PRO C 3 125 ? 137.582 135.169 97.999  1.00 24.91 ? 107 PRO C CD  1 
ATOM   4479 N N   . SER C 3 126 ? 137.855 138.610 97.568  1.00 28.05 ? 108 SER C N   1 
ATOM   4480 C CA  . SER C 3 126 ? 137.561 139.992 97.207  1.00 19.56 ? 108 SER C CA  1 
ATOM   4481 C C   . SER C 3 126 ? 137.406 140.858 98.448  1.00 19.39 ? 108 SER C C   1 
ATOM   4482 O O   . SER C 3 126 ? 137.731 142.051 98.427  1.00 24.37 ? 108 SER C O   1 
ATOM   4483 C CB  . SER C 3 126 ? 136.298 140.050 96.350  1.00 25.21 ? 108 SER C CB  1 
ATOM   4484 O OG  . SER C 3 126 ? 135.275 139.238 96.898  1.00 30.47 ? 108 SER C OG  1 
ATOM   4485 N N   . GLY C 3 127 ? 136.904 140.281 99.529  1.00 24.45 ? 109 GLY C N   1 
ATOM   4486 C CA  . GLY C 3 127 ? 136.773 140.960 100.794 1.00 20.12 ? 109 GLY C CA  1 
ATOM   4487 C C   . GLY C 3 127 ? 135.402 141.530 101.100 1.00 20.83 ? 109 GLY C C   1 
ATOM   4488 O O   . GLY C 3 127 ? 135.262 142.227 102.113 1.00 18.70 ? 109 GLY C O   1 
ATOM   4489 N N   . ASN C 3 128 ? 134.390 141.252 100.266 1.00 19.23 ? 110 ASN C N   1 
ATOM   4490 C CA  . ASN C 3 128 ? 133.051 141.798 100.458 1.00 22.09 ? 110 ASN C CA  1 
ATOM   4491 C C   . ASN C 3 128 ? 131.997 140.704 100.607 1.00 22.10 ? 110 ASN C C   1 
ATOM   4492 O O   . ASN C 3 128 ? 130.811 140.969 100.385 1.00 24.05 ? 110 ASN C O   1 
ATOM   4493 C CB  . ASN C 3 128 ? 132.681 142.724 99.295  1.00 26.84 ? 110 ASN C CB  1 
ATOM   4494 C CG  . ASN C 3 128 ? 132.798 142.048 97.948  1.00 30.26 ? 110 ASN C CG  1 
ATOM   4495 O OD1 . ASN C 3 128 ? 133.176 140.882 97.856  1.00 33.20 ? 110 ASN C OD1 1 
ATOM   4496 N ND2 . ASN C 3 128 ? 132.476 142.781 96.891  1.00 28.90 ? 110 ASN C ND2 1 
ATOM   4497 N N   . TYR C 3 129 ? 132.394 139.489 100.976 1.00 26.56 ? 111 TYR C N   1 
ATOM   4498 C CA  . TYR C 3 129 ? 131.456 138.412 101.248 1.00 32.32 ? 111 TYR C CA  1 
ATOM   4499 C C   . TYR C 3 129 ? 132.026 137.508 102.328 1.00 26.44 ? 111 TYR C C   1 
ATOM   4500 O O   . TYR C 3 129 ? 133.241 137.324 102.431 1.00 29.50 ? 111 TYR C O   1 
ATOM   4501 C CB  . TYR C 3 129 ? 131.139 137.594 99.989  1.00 24.53 ? 111 TYR C CB  1 
ATOM   4502 C CG  . TYR C 3 129 ? 130.148 138.260 99.067  1.00 23.21 ? 111 TYR C CG  1 
ATOM   4503 C CD1 . TYR C 3 129 ? 128.801 138.307 99.387  1.00 23.32 ? 111 TYR C CD1 1 
ATOM   4504 C CD2 . TYR C 3 129 ? 130.558 138.854 97.887  1.00 28.62 ? 111 TYR C CD2 1 
ATOM   4505 C CE1 . TYR C 3 129 ? 127.889 138.917 98.551  1.00 24.68 ? 111 TYR C CE1 1 
ATOM   4506 C CE2 . TYR C 3 129 ? 129.653 139.468 97.045  1.00 33.94 ? 111 TYR C CE2 1 
ATOM   4507 C CZ  . TYR C 3 129 ? 128.321 139.497 97.382  1.00 28.65 ? 111 TYR C CZ  1 
ATOM   4508 O OH  . TYR C 3 129 ? 127.418 140.108 96.546  1.00 27.89 ? 111 TYR C OH  1 
ATOM   4509 N N   . VAL C 3 130 ? 131.127 136.956 103.140 1.00 23.96 ? 112 VAL C N   1 
ATOM   4510 C CA  . VAL C 3 130 ? 131.477 136.046 104.219 1.00 24.95 ? 112 VAL C CA  1 
ATOM   4511 C C   . VAL C 3 130 ? 130.456 134.916 104.228 1.00 27.97 ? 112 VAL C C   1 
ATOM   4512 O O   . VAL C 3 130 ? 129.250 135.136 104.099 1.00 28.55 ? 112 VAL C O   1 
ATOM   4513 C CB  . VAL C 3 130 ? 131.523 136.763 105.587 1.00 22.01 ? 112 VAL C CB  1 
ATOM   4514 C CG1 . VAL C 3 130 ? 131.544 135.765 106.733 1.00 25.11 ? 112 VAL C CG1 1 
ATOM   4515 C CG2 . VAL C 3 130 ? 132.733 137.676 105.660 1.00 18.74 ? 112 VAL C CG2 1 
ATOM   4516 N N   . ALA C 3 131 ? 130.962 133.693 104.385 1.00 26.50 ? 113 ALA C N   1 
ATOM   4517 C CA  . ALA C 3 131 ? 130.150 132.485 104.362 1.00 26.25 ? 113 ALA C CA  1 
ATOM   4518 C C   . ALA C 3 131 ? 130.113 131.860 105.746 1.00 22.23 ? 113 ALA C C   1 
ATOM   4519 O O   . ALA C 3 131 ? 131.031 132.034 106.550 1.00 31.00 ? 113 ALA C O   1 
ATOM   4520 C CB  . ALA C 3 131 ? 130.685 131.467 103.354 1.00 30.01 ? 113 ALA C CB  1 
ATOM   4521 N N   . CYS C 3 132 ? 129.033 131.131 106.014 1.00 28.47 ? 114 CYS C N   1 
ATOM   4522 C CA  . CYS C 3 132 ? 128.802 130.523 107.314 1.00 28.90 ? 114 CYS C CA  1 
ATOM   4523 C C   . CYS C 3 132 ? 128.016 129.233 107.130 1.00 47.12 ? 114 CYS C C   1 
ATOM   4524 O O   . CYS C 3 132 ? 127.108 129.169 106.298 1.00 51.10 ? 114 CYS C O   1 
ATOM   4525 C CB  . CYS C 3 132 ? 128.045 131.489 108.224 1.00 26.73 ? 114 CYS C CB  1 
ATOM   4526 S SG  . CYS C 3 132 ? 128.275 131.226 109.967 1.00 49.35 ? 114 CYS C SG  1 
ATOM   4527 N N   . GLY C 3 133 ? 128.363 128.215 107.912 1.00 43.35 ? 115 GLY C N   1 
ATOM   4528 C CA  . GLY C 3 133 ? 127.701 126.929 107.808 1.00 36.67 ? 115 GLY C CA  1 
ATOM   4529 C C   . GLY C 3 133 ? 127.872 126.128 109.074 1.00 39.94 ? 115 GLY C C   1 
ATOM   4530 O O   . GLY C 3 133 ? 128.867 126.275 109.791 1.00 44.16 ? 115 GLY C O   1 
ATOM   4531 N N   . GLY C 3 134 ? 126.896 125.267 109.350 1.00 47.75 ? 116 GLY C N   1 
ATOM   4532 C CA  . GLY C 3 134 ? 126.937 124.448 110.546 1.00 48.11 ? 116 GLY C CA  1 
ATOM   4533 C C   . GLY C 3 134 ? 125.983 123.272 110.510 1.00 49.44 ? 116 GLY C C   1 
ATOM   4534 O O   . GLY C 3 134 ? 125.787 122.653 109.461 1.00 47.70 ? 116 GLY C O   1 
ATOM   4535 N N   . LEU C 3 135 ? 125.380 122.957 111.658 1.00 55.47 ? 117 LEU C N   1 
ATOM   4536 C CA  . LEU C 3 135 ? 124.478 121.817 111.764 1.00 54.90 ? 117 LEU C CA  1 
ATOM   4537 C C   . LEU C 3 135 ? 123.140 122.038 111.067 1.00 56.15 ? 117 LEU C C   1 
ATOM   4538 O O   . LEU C 3 135 ? 122.365 121.083 110.949 1.00 56.14 ? 117 LEU C O   1 
ATOM   4539 C CB  . LEU C 3 135 ? 124.222 121.480 113.238 1.00 52.91 ? 117 LEU C CB  1 
ATOM   4540 C CG  . LEU C 3 135 ? 125.264 120.628 113.972 1.00 50.31 ? 117 LEU C CG  1 
ATOM   4541 C CD1 . LEU C 3 135 ? 124.949 120.560 115.456 1.00 51.58 ? 117 LEU C CD1 1 
ATOM   4542 C CD2 . LEU C 3 135 ? 125.344 119.228 113.395 1.00 52.22 ? 117 LEU C CD2 1 
ATOM   4543 N N   . ASP C 3 136 ? 122.846 123.253 110.608 1.00 56.58 ? 118 ASP C N   1 
ATOM   4544 C CA  . ASP C 3 136 ? 121.561 123.540 109.969 1.00 58.13 ? 118 ASP C CA  1 
ATOM   4545 C C   . ASP C 3 136 ? 121.531 123.148 108.494 1.00 54.78 ? 118 ASP C C   1 
ATOM   4546 O O   . ASP C 3 136 ? 120.532 123.420 107.821 1.00 53.68 ? 118 ASP C O   1 
ATOM   4547 C CB  . ASP C 3 136 ? 121.168 125.030 110.099 1.00 59.51 ? 118 ASP C CB  1 
ATOM   4548 C CG  . ASP C 3 136 ? 122.332 125.988 109.915 1.00 63.49 ? 118 ASP C CG  1 
ATOM   4549 O OD1 . ASP C 3 136 ? 123.185 126.066 110.823 1.00 63.51 ? 118 ASP C OD1 1 
ATOM   4550 O OD2 . ASP C 3 136 ? 122.390 126.662 108.865 1.00 62.90 ? 118 ASP C OD2 1 
ATOM   4551 N N   . ASN C 3 137 ? 122.601 122.542 107.972 1.00 52.63 ? 119 ASN C N   1 
ATOM   4552 C CA  . ASN C 3 137 ? 122.654 121.987 106.617 1.00 53.88 ? 119 ASN C CA  1 
ATOM   4553 C C   . ASN C 3 137 ? 122.613 123.064 105.534 1.00 55.11 ? 119 ASN C C   1 
ATOM   4554 O O   . ASN C 3 137 ? 122.469 122.740 104.351 1.00 57.57 ? 119 ASN C O   1 
ATOM   4555 C CB  . ASN C 3 137 ? 121.517 120.982 106.377 1.00 58.74 ? 119 ASN C CB  1 
ATOM   4556 C CG  . ASN C 3 137 ? 121.615 119.764 107.270 1.00 61.95 ? 119 ASN C CG  1 
ATOM   4557 O OD1 . ASN C 3 137 ? 122.463 118.905 107.072 1.00 61.89 ? 119 ASN C OD1 1 
ATOM   4558 N ND2 . ASN C 3 137 ? 120.733 119.682 108.256 1.00 56.87 ? 119 ASN C ND2 1 
ATOM   4559 N N   . ILE C 3 138 ? 122.746 124.338 105.906 1.00 48.40 ? 120 ILE C N   1 
ATOM   4560 C CA  . ILE C 3 138 ? 122.578 125.461 104.991 1.00 46.43 ? 120 ILE C CA  1 
ATOM   4561 C C   . ILE C 3 138 ? 123.825 126.330 105.070 1.00 50.88 ? 120 ILE C C   1 
ATOM   4562 O O   . ILE C 3 138 ? 124.271 126.683 106.167 1.00 48.91 ? 120 ILE C O   1 
ATOM   4563 C CB  . ILE C 3 138 ? 121.314 126.277 105.331 1.00 46.19 ? 120 ILE C CB  1 
ATOM   4564 C CG1 . ILE C 3 138 ? 120.070 125.559 104.808 1.00 49.55 ? 120 ILE C CG1 1 
ATOM   4565 C CG2 . ILE C 3 138 ? 121.367 127.685 104.734 1.00 47.31 ? 120 ILE C CG2 1 
ATOM   4566 C CD1 . ILE C 3 138 ? 118.883 125.651 105.736 1.00 46.89 ? 120 ILE C CD1 1 
ATOM   4567 N N   . CYS C 3 139 ? 124.383 126.668 103.910 1.00 45.10 ? 121 CYS C N   1 
ATOM   4568 C CA  . CYS C 3 139 ? 125.489 127.611 103.806 1.00 36.13 ? 121 CYS C CA  1 
ATOM   4569 C C   . CYS C 3 139 ? 124.911 128.994 103.540 1.00 41.08 ? 121 CYS C C   1 
ATOM   4570 O O   . CYS C 3 139 ? 124.282 129.216 102.499 1.00 48.83 ? 121 CYS C O   1 
ATOM   4571 C CB  . CYS C 3 139 ? 126.451 127.212 102.688 1.00 34.55 ? 121 CYS C CB  1 
ATOM   4572 S SG  . CYS C 3 139 ? 128.062 128.018 102.770 1.00 35.37 ? 121 CYS C SG  1 
ATOM   4573 N N   . SER C 3 140 ? 125.122 129.915 104.475 1.00 27.69 ? 122 SER C N   1 
ATOM   4574 C CA  . SER C 3 140 ? 124.606 131.272 104.383 1.00 33.46 ? 122 SER C CA  1 
ATOM   4575 C C   . SER C 3 140 ? 125.737 132.226 104.031 1.00 33.95 ? 122 SER C C   1 
ATOM   4576 O O   . SER C 3 140 ? 126.796 132.207 104.665 1.00 34.50 ? 122 SER C O   1 
ATOM   4577 C CB  . SER C 3 140 ? 123.951 131.695 105.698 1.00 39.44 ? 122 SER C CB  1 
ATOM   4578 O OG  . SER C 3 140 ? 124.747 131.313 106.803 1.00 38.91 ? 122 SER C OG  1 
ATOM   4579 N N   . ILE C 3 141 ? 125.503 133.057 103.018 1.00 38.54 ? 123 ILE C N   1 
ATOM   4580 C CA  . ILE C 3 141 ? 126.484 134.010 102.513 1.00 41.33 ? 123 ILE C CA  1 
ATOM   4581 C C   . ILE C 3 141 ? 126.005 135.408 102.870 1.00 48.74 ? 123 ILE C C   1 
ATOM   4582 O O   . ILE C 3 141 ? 124.843 135.751 102.627 1.00 50.16 ? 123 ILE C O   1 
ATOM   4583 C CB  . ILE C 3 141 ? 126.688 133.864 100.994 1.00 26.71 ? 123 ILE C CB  1 
ATOM   4584 C CG1 . ILE C 3 141 ? 127.443 132.568 100.699 1.00 30.96 ? 123 ILE C CG1 1 
ATOM   4585 C CG2 . ILE C 3 141 ? 127.450 135.065 100.431 1.00 37.82 ? 123 ILE C CG2 1 
ATOM   4586 C CD1 . ILE C 3 141 ? 127.348 132.110 99.266  1.00 40.70 ? 123 ILE C CD1 1 
ATOM   4587 N N   . TYR C 3 142 ? 126.899 136.204 103.452 1.00 32.16 ? 124 TYR C N   1 
ATOM   4588 C CA  . TYR C 3 142 ? 126.596 137.549 103.918 1.00 22.56 ? 124 TYR C CA  1 
ATOM   4589 C C   . TYR C 3 142 ? 127.341 138.576 103.082 1.00 29.64 ? 124 TYR C C   1 
ATOM   4590 O O   . TYR C 3 142 ? 128.548 138.455 102.862 1.00 34.09 ? 124 TYR C O   1 
ATOM   4591 C CB  . TYR C 3 142 ? 126.969 137.708 105.391 1.00 23.73 ? 124 TYR C CB  1 
ATOM   4592 C CG  . TYR C 3 142 ? 126.343 136.666 106.281 1.00 29.13 ? 124 TYR C CG  1 
ATOM   4593 C CD1 . TYR C 3 142 ? 126.983 135.466 106.540 1.00 33.86 ? 124 TYR C CD1 1 
ATOM   4594 C CD2 . TYR C 3 142 ? 125.109 136.888 106.867 1.00 30.07 ? 124 TYR C CD2 1 
ATOM   4595 C CE1 . TYR C 3 142 ? 126.405 134.516 107.353 1.00 31.52 ? 124 TYR C CE1 1 
ATOM   4596 C CE2 . TYR C 3 142 ? 124.529 135.947 107.682 1.00 29.31 ? 124 TYR C CE2 1 
ATOM   4597 C CZ  . TYR C 3 142 ? 125.179 134.761 107.919 1.00 30.95 ? 124 TYR C CZ  1 
ATOM   4598 O OH  . TYR C 3 142 ? 124.596 133.820 108.733 1.00 40.31 ? 124 TYR C OH  1 
ATOM   4599 N N   . ASN C 3 143 ? 126.609 139.583 102.618 1.00 31.80 ? 125 ASN C N   1 
ATOM   4600 C CA  . ASN C 3 143 ? 127.168 140.690 101.858 1.00 24.41 ? 125 ASN C CA  1 
ATOM   4601 C C   . ASN C 3 143 ? 127.581 141.791 102.822 1.00 25.87 ? 125 ASN C C   1 
ATOM   4602 O O   . ASN C 3 143 ? 126.733 142.371 103.506 1.00 36.54 ? 125 ASN C O   1 
ATOM   4603 C CB  . ASN C 3 143 ? 126.146 141.215 100.850 1.00 26.53 ? 125 ASN C CB  1 
ATOM   4604 C CG  . ASN C 3 143 ? 126.678 142.357 100.016 1.00 27.20 ? 125 ASN C CG  1 
ATOM   4605 O OD1 . ASN C 3 143 ? 127.887 142.534 99.882  1.00 32.46 ? 125 ASN C OD1 1 
ATOM   4606 N ND2 . ASN C 3 143 ? 125.772 143.137 99.440  1.00 28.11 ? 125 ASN C ND2 1 
ATOM   4607 N N   . LEU C 3 144 ? 128.881 142.078 102.874 1.00 25.76 ? 126 LEU C N   1 
ATOM   4608 C CA  . LEU C 3 144 ? 129.411 143.049 103.825 1.00 24.33 ? 126 LEU C CA  1 
ATOM   4609 C C   . LEU C 3 144 ? 129.280 144.475 103.301 1.00 22.20 ? 126 LEU C C   1 
ATOM   4610 O O   . LEU C 3 144 ? 128.655 145.324 103.944 1.00 19.69 ? 126 LEU C O   1 
ATOM   4611 C CB  . LEU C 3 144 ? 130.878 142.734 104.136 1.00 23.47 ? 126 LEU C CB  1 
ATOM   4612 C CG  . LEU C 3 144 ? 131.211 141.399 104.805 1.00 17.64 ? 126 LEU C CG  1 
ATOM   4613 C CD1 . LEU C 3 144 ? 132.686 141.372 105.145 1.00 26.01 ? 126 LEU C CD1 1 
ATOM   4614 C CD2 . LEU C 3 144 ? 130.379 141.148 106.050 1.00 20.23 ? 126 LEU C CD2 1 
ATOM   4615 N N   . LYS C 3 145 ? 129.864 144.751 102.139 1.00 25.05 ? 127 LYS C N   1 
ATOM   4616 C CA  . LYS C 3 145 ? 129.828 146.085 101.551 1.00 28.29 ? 127 LYS C CA  1 
ATOM   4617 C C   . LYS C 3 145 ? 128.508 146.251 100.813 1.00 26.46 ? 127 LYS C C   1 
ATOM   4618 O O   . LYS C 3 145 ? 128.265 145.591 99.799  1.00 33.70 ? 127 LYS C O   1 
ATOM   4619 C CB  . LYS C 3 145 ? 131.012 146.309 100.614 1.00 23.95 ? 127 LYS C CB  1 
ATOM   4620 C CG  . LYS C 3 145 ? 132.341 145.813 101.150 1.00 22.40 ? 127 LYS C CG  1 
ATOM   4621 C CD  . LYS C 3 145 ? 133.481 146.217 100.228 1.00 17.87 ? 127 LYS C CD  1 
ATOM   4622 C CE  . LYS C 3 145 ? 134.849 145.844 100.787 1.00 24.30 ? 127 LYS C CE  1 
ATOM   4623 N NZ  . LYS C 3 145 ? 135.071 146.293 102.190 1.00 32.52 ? 127 LYS C NZ  1 
ATOM   4624 N N   . THR C 3 146 ? 127.659 147.134 101.325 1.00 29.96 ? 128 THR C N   1 
ATOM   4625 C CA  . THR C 3 146 ? 126.349 147.381 100.745 1.00 30.35 ? 128 THR C CA  1 
ATOM   4626 C C   . THR C 3 146 ? 125.896 148.762 101.186 1.00 33.68 ? 128 THR C C   1 
ATOM   4627 O O   . THR C 3 146 ? 126.442 149.345 102.124 1.00 37.21 ? 128 THR C O   1 
ATOM   4628 C CB  . THR C 3 146 ? 125.332 146.314 101.168 1.00 30.21 ? 128 THR C CB  1 
ATOM   4629 O OG1 . THR C 3 146 ? 124.017 146.712 100.759 1.00 34.54 ? 128 THR C OG1 1 
ATOM   4630 C CG2 . THR C 3 146 ? 125.344 146.101 102.682 1.00 19.59 ? 128 THR C CG2 1 
ATOM   4631 N N   . ARG C 3 147 ? 124.879 149.277 100.503 1.00 29.69 ? 129 ARG C N   1 
ATOM   4632 C CA  . ARG C 3 147 ? 124.215 150.466 101.001 1.00 25.46 ? 129 ARG C CA  1 
ATOM   4633 C C   . ARG C 3 147 ? 123.526 150.152 102.329 1.00 28.15 ? 129 ARG C C   1 
ATOM   4634 O O   . ARG C 3 147 ? 123.503 149.012 102.797 1.00 33.49 ? 129 ARG C O   1 
ATOM   4635 C CB  . ARG C 3 147 ? 123.217 151.006 99.973  1.00 23.22 ? 129 ARG C CB  1 
ATOM   4636 C CG  . ARG C 3 147 ? 123.799 151.306 98.591  1.00 30.64 ? 129 ARG C CG  1 
ATOM   4637 C CD  . ARG C 3 147 ? 124.684 152.551 98.594  1.00 37.81 ? 129 ARG C CD  1 
ATOM   4638 N NE  . ARG C 3 147 ? 123.923 153.772 98.350  1.00 39.17 ? 129 ARG C NE  1 
ATOM   4639 C CZ  . ARG C 3 147 ? 124.430 154.999 98.358  1.00 34.11 ? 129 ARG C CZ  1 
ATOM   4640 N NH1 . ARG C 3 147 ? 125.712 155.224 98.608  1.00 29.20 ? 129 ARG C NH1 1 
ATOM   4641 N NH2 . ARG C 3 147 ? 123.630 156.032 98.112  1.00 31.59 ? 129 ARG C NH2 1 
ATOM   4642 N N   . GLU C 3 148 ? 123.002 151.206 102.951 1.00 28.22 ? 130 GLU C N   1 
ATOM   4643 C CA  . GLU C 3 148 ? 122.401 151.216 104.287 1.00 29.96 ? 130 GLU C CA  1 
ATOM   4644 C C   . GLU C 3 148 ? 123.193 150.437 105.339 1.00 28.65 ? 130 GLU C C   1 
ATOM   4645 O O   . GLU C 3 148 ? 122.604 149.861 106.258 1.00 26.08 ? 130 GLU C O   1 
ATOM   4646 C CB  . GLU C 3 148 ? 120.937 150.725 104.254 1.00 29.34 ? 130 GLU C CB  1 
ATOM   4647 C CG  . GLU C 3 148 ? 120.619 149.373 103.622 1.00 28.51 ? 130 GLU C CG  1 
ATOM   4648 C CD  . GLU C 3 148 ? 120.226 149.479 102.161 1.00 33.10 ? 130 GLU C CD  1 
ATOM   4649 O OE1 . GLU C 3 148 ? 120.686 150.416 101.480 1.00 40.31 ? 130 GLU C OE1 1 
ATOM   4650 O OE2 . GLU C 3 148 ? 119.452 148.621 101.690 1.00 30.90 ? 130 GLU C OE2 1 
ATOM   4651 N N   . GLY C 3 149 ? 124.517 150.416 105.207 1.00 35.17 ? 131 GLY C N   1 
ATOM   4652 C CA  . GLY C 3 149 ? 125.449 150.103 106.286 1.00 33.67 ? 131 GLY C CA  1 
ATOM   4653 C C   . GLY C 3 149 ? 125.143 148.940 107.207 1.00 35.41 ? 131 GLY C C   1 
ATOM   4654 O O   . GLY C 3 149 ? 125.574 148.957 108.368 1.00 34.17 ? 131 GLY C O   1 
ATOM   4655 N N   . ASN C 3 150 ? 124.408 147.934 106.731 1.00 35.37 ? 132 ASN C N   1 
ATOM   4656 C CA  . ASN C 3 150 ? 124.108 146.750 107.526 1.00 31.73 ? 132 ASN C CA  1 
ATOM   4657 C C   . ASN C 3 150 ? 124.365 145.498 106.700 1.00 36.60 ? 132 ASN C C   1 
ATOM   4658 O O   . ASN C 3 150 ? 124.246 145.507 105.472 1.00 40.75 ? 132 ASN C O   1 
ATOM   4659 C CB  . ASN C 3 150 ? 122.663 146.774 108.062 1.00 31.43 ? 132 ASN C CB  1 
ATOM   4660 C CG  . ASN C 3 150 ? 121.614 146.568 106.980 1.00 39.46 ? 132 ASN C CG  1 
ATOM   4661 O OD1 . ASN C 3 150 ? 121.886 146.693 105.787 1.00 42.11 ? 132 ASN C OD1 1 
ATOM   4662 N ND2 . ASN C 3 150 ? 120.397 146.249 107.403 1.00 40.97 ? 132 ASN C ND2 1 
ATOM   4663 N N   . VAL C 3 151 ? 124.731 144.426 107.393 1.00 30.05 ? 133 VAL C N   1 
ATOM   4664 C CA  . VAL C 3 151 ? 125.079 143.159 106.762 1.00 26.46 ? 133 VAL C CA  1 
ATOM   4665 C C   . VAL C 3 151 ? 123.833 142.290 106.692 1.00 35.30 ? 133 VAL C C   1 
ATOM   4666 O O   . VAL C 3 151 ? 123.389 141.744 107.709 1.00 40.81 ? 133 VAL C O   1 
ATOM   4667 C CB  . VAL C 3 151 ? 126.201 142.453 107.540 1.00 18.80 ? 133 VAL C CB  1 
ATOM   4668 C CG1 . VAL C 3 151 ? 126.621 141.175 106.834 1.00 28.41 ? 133 VAL C CG1 1 
ATOM   4669 C CG2 . VAL C 3 151 ? 127.385 143.391 107.725 1.00 30.37 ? 133 VAL C CG2 1 
ATOM   4670 N N   . ARG C 3 152 ? 123.274 142.153 105.490 1.00 34.17 ? 134 ARG C N   1 
ATOM   4671 C CA  . ARG C 3 152 ? 122.080 141.354 105.256 1.00 35.51 ? 134 ARG C CA  1 
ATOM   4672 C C   . ARG C 3 152 ? 122.461 140.042 104.590 1.00 31.33 ? 134 ARG C C   1 
ATOM   4673 O O   . ARG C 3 152 ? 123.469 139.954 103.885 1.00 38.49 ? 134 ARG C O   1 
ATOM   4674 C CB  . ARG C 3 152 ? 121.051 142.113 104.396 1.00 40.03 ? 134 ARG C CB  1 
ATOM   4675 C CG  . ARG C 3 152 ? 121.514 142.504 102.994 1.00 40.62 ? 134 ARG C CG  1 
ATOM   4676 C CD  . ARG C 3 152 ? 120.345 143.033 102.176 1.00 39.56 ? 134 ARG C CD  1 
ATOM   4677 N NE  . ARG C 3 152 ? 120.749 144.013 101.173 1.00 47.50 ? 134 ARG C NE  1 
ATOM   4678 C CZ  . ARG C 3 152 ? 121.166 145.245 101.439 1.00 43.18 ? 134 ARG C CZ  1 
ATOM   4679 N NH1 . ARG C 3 152 ? 121.246 145.702 102.680 1.00 33.68 ? 134 ARG C NH1 1 
ATOM   4680 N NH2 . ARG C 3 152 ? 121.507 146.044 100.432 1.00 38.21 ? 134 ARG C NH2 1 
ATOM   4681 N N   . VAL C 3 153 ? 121.636 139.020 104.817 1.00 35.03 ? 135 VAL C N   1 
ATOM   4682 C CA  . VAL C 3 153 ? 121.889 137.712 104.230 1.00 38.82 ? 135 VAL C CA  1 
ATOM   4683 C C   . VAL C 3 153 ? 121.749 137.810 102.719 1.00 38.68 ? 135 VAL C C   1 
ATOM   4684 O O   . VAL C 3 153 ? 120.677 138.146 102.199 1.00 42.29 ? 135 VAL C O   1 
ATOM   4685 C CB  . VAL C 3 153 ? 120.924 136.662 104.802 1.00 39.90 ? 135 VAL C CB  1 
ATOM   4686 C CG1 . VAL C 3 153 ? 121.120 135.330 104.080 1.00 33.68 ? 135 VAL C CG1 1 
ATOM   4687 C CG2 . VAL C 3 153 ? 121.119 136.503 106.306 1.00 43.81 ? 135 VAL C CG2 1 
ATOM   4688 N N   . SER C 3 154 ? 122.831 137.509 102.003 1.00 31.32 ? 136 SER C N   1 
ATOM   4689 C CA  . SER C 3 154 ? 122.808 137.515 100.547 1.00 30.00 ? 136 SER C CA  1 
ATOM   4690 C C   . SER C 3 154 ? 122.016 136.328 100.013 1.00 42.92 ? 136 SER C C   1 
ATOM   4691 O O   . SER C 3 154 ? 121.019 136.511 99.310  1.00 43.11 ? 136 SER C O   1 
ATOM   4692 C CB  . SER C 3 154 ? 124.239 137.507 99.994  1.00 26.34 ? 136 SER C CB  1 
ATOM   4693 O OG  . SER C 3 154 ? 124.238 137.509 98.578  1.00 32.86 ? 136 SER C OG  1 
ATOM   4694 N N   . ARG C 3 155 ? 122.430 135.109 100.360 1.00 47.83 ? 137 ARG C N   1 
ATOM   4695 C CA  . ARG C 3 155 ? 121.757 133.894 99.925  1.00 38.37 ? 137 ARG C CA  1 
ATOM   4696 C C   . ARG C 3 155 ? 121.912 132.810 100.980 1.00 42.54 ? 137 ARG C C   1 
ATOM   4697 O O   . ARG C 3 155 ? 122.873 132.807 101.754 1.00 40.23 ? 137 ARG C O   1 
ATOM   4698 C CB  . ARG C 3 155 ? 122.316 133.382 98.597  1.00 31.97 ? 137 ARG C CB  1 
ATOM   4699 C CG  . ARG C 3 155 ? 122.166 134.347 97.438  1.00 35.54 ? 137 ARG C CG  1 
ATOM   4700 C CD  . ARG C 3 155 ? 122.113 133.612 96.121  1.00 43.20 ? 137 ARG C CD  1 
ATOM   4701 N NE  . ARG C 3 155 ? 120.905 132.812 95.955  1.00 48.09 ? 137 ARG C NE  1 
ATOM   4702 C CZ  . ARG C 3 155 ? 119.683 133.301 95.779  1.00 46.17 ? 137 ARG C CZ  1 
ATOM   4703 N NH1 . ARG C 3 155 ? 119.455 134.604 95.711  1.00 42.21 ? 137 ARG C NH1 1 
ATOM   4704 N NH2 . ARG C 3 155 ? 118.661 132.459 95.660  1.00 43.17 ? 137 ARG C NH2 1 
ATOM   4705 N N   . GLU C 3 156 ? 120.953 131.883 100.993 1.00 45.41 ? 138 GLU C N   1 
ATOM   4706 C CA  . GLU C 3 156 ? 120.983 130.688 101.840 1.00 43.48 ? 138 GLU C CA  1 
ATOM   4707 C C   . GLU C 3 156 ? 121.061 129.486 100.904 1.00 44.62 ? 138 GLU C C   1 
ATOM   4708 O O   . GLU C 3 156 ? 120.044 129.050 100.357 1.00 49.60 ? 138 GLU C O   1 
ATOM   4709 C CB  . GLU C 3 156 ? 119.758 130.611 102.748 1.00 43.30 ? 138 GLU C CB  1 
ATOM   4710 C CG  . GLU C 3 156 ? 119.719 131.671 103.845 1.00 46.24 ? 138 GLU C CG  1 
ATOM   4711 C CD  . GLU C 3 156 ? 118.308 132.087 104.241 1.00 49.11 ? 138 GLU C CD  1 
ATOM   4712 O OE1 . GLU C 3 156 ? 117.418 132.155 103.368 1.00 49.90 ? 138 GLU C OE1 1 
ATOM   4713 O OE2 . GLU C 3 156 ? 118.089 132.346 105.443 1.00 46.36 ? 138 GLU C OE2 1 
ATOM   4714 N N   . LEU C 3 157 ? 122.266 128.957 100.714 1.00 33.25 ? 139 LEU C N   1 
ATOM   4715 C CA  . LEU C 3 157 ? 122.463 127.801 99.849  1.00 37.37 ? 139 LEU C CA  1 
ATOM   4716 C C   . LEU C 3 157 ? 122.082 126.534 100.605 1.00 43.47 ? 139 LEU C C   1 
ATOM   4717 O O   . LEU C 3 157 ? 122.573 126.297 101.713 1.00 40.27 ? 139 LEU C O   1 
ATOM   4718 C CB  . LEU C 3 157 ? 123.909 127.727 99.366  1.00 36.46 ? 139 LEU C CB  1 
ATOM   4719 C CG  . LEU C 3 157 ? 124.502 128.991 98.737  1.00 36.64 ? 139 LEU C CG  1 
ATOM   4720 C CD1 . LEU C 3 157 ? 126.004 128.847 98.585  1.00 34.98 ? 139 LEU C CD1 1 
ATOM   4721 C CD2 . LEU C 3 157 ? 123.851 129.282 97.397  1.00 39.13 ? 139 LEU C CD2 1 
ATOM   4722 N N   . ALA C 3 158 ? 121.205 125.729 100.006 1.00 45.34 ? 140 ALA C N   1 
ATOM   4723 C CA  . ALA C 3 158 ? 120.714 124.497 100.605 1.00 39.72 ? 140 ALA C CA  1 
ATOM   4724 C C   . ALA C 3 158 ? 120.778 123.374 99.579  1.00 38.71 ? 140 ALA C C   1 
ATOM   4725 O O   . ALA C 3 158 ? 120.789 123.612 98.369  1.00 37.20 ? 140 ALA C O   1 
ATOM   4726 C CB  . ALA C 3 158 ? 119.277 124.656 101.119 1.00 36.95 ? 140 ALA C CB  1 
ATOM   4727 N N   . GLY C 3 159 ? 120.803 122.141 100.084 1.00 37.11 ? 141 GLY C N   1 
ATOM   4728 C CA  . GLY C 3 159 ? 120.906 120.963 99.242  1.00 39.10 ? 141 GLY C CA  1 
ATOM   4729 C C   . GLY C 3 159 ? 121.824 119.876 99.768  1.00 34.60 ? 141 GLY C C   1 
ATOM   4730 O O   . GLY C 3 159 ? 122.029 118.865 99.091  1.00 29.49 ? 141 GLY C O   1 
ATOM   4731 N N   . HIS C 3 160 ? 122.385 120.064 100.959 1.00 37.58 ? 142 HIS C N   1 
ATOM   4732 C CA  . HIS C 3 160 ? 123.190 119.050 101.623 1.00 37.95 ? 142 HIS C CA  1 
ATOM   4733 C C   . HIS C 3 160 ? 122.331 118.265 102.608 1.00 43.26 ? 142 HIS C C   1 
ATOM   4734 O O   . HIS C 3 160 ? 121.536 118.829 103.363 1.00 41.70 ? 142 HIS C O   1 
ATOM   4735 C CB  . HIS C 3 160 ? 124.371 119.688 102.358 1.00 38.48 ? 142 HIS C CB  1 
ATOM   4736 C CG  . HIS C 3 160 ? 125.541 119.994 101.476 1.00 40.21 ? 142 HIS C CG  1 
ATOM   4737 N ND1 . HIS C 3 160 ? 126.187 119.029 100.733 1.00 45.65 ? 142 HIS C ND1 1 
ATOM   4738 C CD2 . HIS C 3 160 ? 126.194 121.154 101.231 1.00 40.10 ? 142 HIS C CD2 1 
ATOM   4739 C CE1 . HIS C 3 160 ? 127.180 119.583 100.061 1.00 38.09 ? 142 HIS C CE1 1 
ATOM   4740 N NE2 . HIS C 3 160 ? 127.206 120.872 100.346 1.00 38.95 ? 142 HIS C NE2 1 
ATOM   4741 N N   . THR C 3 161 ? 122.505 116.944 102.592 1.00 46.07 ? 143 THR C N   1 
ATOM   4742 C CA  . THR C 3 161 ? 121.777 116.045 103.479 1.00 44.67 ? 143 THR C CA  1 
ATOM   4743 C C   . THR C 3 161 ? 122.519 115.782 104.784 1.00 44.03 ? 143 THR C C   1 
ATOM   4744 O O   . THR C 3 161 ? 122.040 114.997 105.608 1.00 47.92 ? 143 THR C O   1 
ATOM   4745 C CB  . THR C 3 161 ? 121.489 114.716 102.775 1.00 47.70 ? 143 THR C CB  1 
ATOM   4746 O OG1 . THR C 3 161 ? 122.654 113.885 102.818 1.00 50.10 ? 143 THR C OG1 1 
ATOM   4747 C CG2 . THR C 3 161 ? 121.081 114.946 101.324 1.00 46.91 ? 143 THR C CG2 1 
ATOM   4748 N N   . GLY C 3 162 ? 123.682 116.413 104.987 1.00 42.00 ? 144 GLY C N   1 
ATOM   4749 C CA  . GLY C 3 162 ? 124.421 116.278 106.223 1.00 44.05 ? 144 GLY C CA  1 
ATOM   4750 C C   . GLY C 3 162 ? 124.998 117.618 106.630 1.00 46.41 ? 144 GLY C C   1 
ATOM   4751 O O   . GLY C 3 162 ? 124.967 118.584 105.866 1.00 47.14 ? 144 GLY C O   1 
ATOM   4752 N N   . TYR C 3 163 ? 125.510 117.667 107.856 1.00 50.10 ? 145 TYR C N   1 
ATOM   4753 C CA  . TYR C 3 163 ? 125.947 118.938 108.416 1.00 47.87 ? 145 TYR C CA  1 
ATOM   4754 C C   . TYR C 3 163 ? 127.142 119.479 107.644 1.00 44.60 ? 145 TYR C C   1 
ATOM   4755 O O   . TYR C 3 163 ? 128.053 118.732 107.277 1.00 47.84 ? 145 TYR C O   1 
ATOM   4756 C CB  . TYR C 3 163 ? 126.300 118.781 109.895 1.00 49.18 ? 145 TYR C CB  1 
ATOM   4757 C CG  . TYR C 3 163 ? 127.505 117.914 110.177 1.00 47.03 ? 145 TYR C CG  1 
ATOM   4758 C CD1 . TYR C 3 163 ? 127.380 116.540 110.314 1.00 50.10 ? 145 TYR C CD1 1 
ATOM   4759 C CD2 . TYR C 3 163 ? 128.766 118.472 110.321 1.00 50.15 ? 145 TYR C CD2 1 
ATOM   4760 C CE1 . TYR C 3 163 ? 128.477 115.748 110.576 1.00 53.19 ? 145 TYR C CE1 1 
ATOM   4761 C CE2 . TYR C 3 163 ? 129.868 117.688 110.582 1.00 50.66 ? 145 TYR C CE2 1 
ATOM   4762 C CZ  . TYR C 3 163 ? 129.718 116.329 110.712 1.00 50.60 ? 145 TYR C CZ  1 
ATOM   4763 O OH  . TYR C 3 163 ? 130.815 115.542 110.971 1.00 46.22 ? 145 TYR C OH  1 
ATOM   4764 N N   . LEU C 3 164 ? 127.125 120.783 107.391 1.00 41.61 ? 146 LEU C N   1 
ATOM   4765 C CA  . LEU C 3 164 ? 128.225 121.430 106.692 1.00 42.63 ? 146 LEU C CA  1 
ATOM   4766 C C   . LEU C 3 164 ? 129.452 121.495 107.592 1.00 40.46 ? 146 LEU C C   1 
ATOM   4767 O O   . LEU C 3 164 ? 129.358 121.886 108.759 1.00 39.90 ? 146 LEU C O   1 
ATOM   4768 C CB  . LEU C 3 164 ? 127.802 122.830 106.250 1.00 39.77 ? 146 LEU C CB  1 
ATOM   4769 C CG  . LEU C 3 164 ? 128.685 123.654 105.308 1.00 34.55 ? 146 LEU C CG  1 
ATOM   4770 C CD1 . LEU C 3 164 ? 129.348 122.838 104.221 1.00 32.23 ? 146 LEU C CD1 1 
ATOM   4771 C CD2 . LEU C 3 164 ? 127.841 124.741 104.682 1.00 40.62 ? 146 LEU C CD2 1 
ATOM   4772 N N   . SER C 3 165 ? 130.606 121.112 107.043 1.00 29.75 ? 147 SER C N   1 
ATOM   4773 C CA  . SER C 3 165 ? 131.851 121.014 107.796 1.00 28.24 ? 147 SER C CA  1 
ATOM   4774 C C   . SER C 3 165 ? 132.885 122.059 107.415 1.00 27.42 ? 147 SER C C   1 
ATOM   4775 O O   . SER C 3 165 ? 133.671 122.464 108.272 1.00 33.12 ? 147 SER C O   1 
ATOM   4776 C CB  . SER C 3 165 ? 132.472 119.626 107.609 1.00 35.15 ? 147 SER C CB  1 
ATOM   4777 O OG  . SER C 3 165 ? 133.460 119.379 108.592 1.00 35.70 ? 147 SER C OG  1 
ATOM   4778 N N   . CYS C 3 166 ? 132.916 122.494 106.159 1.00 28.16 ? 148 CYS C N   1 
ATOM   4779 C CA  . CYS C 3 166 ? 133.878 123.498 105.729 1.00 20.18 ? 148 CYS C CA  1 
ATOM   4780 C C   . CYS C 3 166 ? 133.360 124.154 104.460 1.00 29.07 ? 148 CYS C C   1 
ATOM   4781 O O   . CYS C 3 166 ? 132.578 123.565 103.711 1.00 51.27 ? 148 CYS C O   1 
ATOM   4782 C CB  . CYS C 3 166 ? 135.263 122.884 105.498 1.00 22.22 ? 148 CYS C CB  1 
ATOM   4783 S SG  . CYS C 3 166 ? 136.575 124.087 105.222 1.00 34.60 ? 148 CYS C SG  1 
ATOM   4784 N N   . CYS C 3 167 ? 133.804 125.387 104.232 1.00 18.11 ? 149 CYS C N   1 
ATOM   4785 C CA  . CYS C 3 167 ? 133.415 126.140 103.050 1.00 19.32 ? 149 CYS C CA  1 
ATOM   4786 C C   . CYS C 3 167 ? 134.536 127.104 102.698 1.00 26.19 ? 149 CYS C C   1 
ATOM   4787 O O   . CYS C 3 167 ? 135.158 127.688 103.588 1.00 36.67 ? 149 CYS C O   1 
ATOM   4788 C CB  . CYS C 3 167 ? 132.107 126.904 103.275 1.00 24.04 ? 149 CYS C CB  1 
ATOM   4789 S SG  . CYS C 3 167 ? 132.124 128.012 104.697 1.00 39.36 ? 149 CYS C SG  1 
ATOM   4790 N N   . ARG C 3 168 ? 134.791 127.259 101.400 1.00 21.19 ? 150 ARG C N   1 
ATOM   4791 C CA  . ARG C 3 168 ? 135.872 128.107 100.921 1.00 14.88 ? 150 ARG C CA  1 
ATOM   4792 C C   . ARG C 3 168 ? 135.447 128.771 99.622  1.00 19.30 ? 150 ARG C C   1 
ATOM   4793 O O   . ARG C 3 168 ? 134.977 128.101 98.702  1.00 32.64 ? 150 ARG C O   1 
ATOM   4794 C CB  . ARG C 3 168 ? 137.156 127.301 100.694 1.00 17.58 ? 150 ARG C CB  1 
ATOM   4795 C CG  . ARG C 3 168 ? 137.862 126.849 101.962 1.00 19.26 ? 150 ARG C CG  1 
ATOM   4796 C CD  . ARG C 3 168 ? 138.450 128.013 102.733 1.00 19.94 ? 150 ARG C CD  1 
ATOM   4797 N NE  . ARG C 3 168 ? 139.330 127.561 103.808 1.00 26.50 ? 150 ARG C NE  1 
ATOM   4798 C CZ  . ARG C 3 168 ? 139.055 127.584 105.109 1.00 32.81 ? 150 ARG C CZ  1 
ATOM   4799 N NH1 . ARG C 3 168 ? 137.882 127.988 105.576 1.00 31.15 ? 150 ARG C NH1 1 
ATOM   4800 N NH2 . ARG C 3 168 ? 139.985 127.183 105.970 1.00 34.48 ? 150 ARG C NH2 1 
ATOM   4801 N N   . PHE C 3 169 ? 135.624 130.086 99.552  1.00 20.28 ? 151 PHE C N   1 
ATOM   4802 C CA  . PHE C 3 169 ? 135.299 130.828 98.343  1.00 22.56 ? 151 PHE C CA  1 
ATOM   4803 C C   . PHE C 3 169 ? 136.321 130.530 97.256  1.00 22.18 ? 151 PHE C C   1 
ATOM   4804 O O   . PHE C 3 169 ? 137.531 130.572 97.499  1.00 31.60 ? 151 PHE C O   1 
ATOM   4805 C CB  . PHE C 3 169 ? 135.269 132.329 98.624  1.00 30.10 ? 151 PHE C CB  1 
ATOM   4806 C CG  . PHE C 3 169 ? 133.957 132.822 99.152  1.00 25.38 ? 151 PHE C CG  1 
ATOM   4807 C CD1 . PHE C 3 169 ? 133.696 132.812 100.507 1.00 22.35 ? 151 PHE C CD1 1 
ATOM   4808 C CD2 . PHE C 3 169 ? 132.986 133.300 98.294  1.00 25.84 ? 151 PHE C CD2 1 
ATOM   4809 C CE1 . PHE C 3 169 ? 132.494 133.266 100.994 1.00 24.02 ? 151 PHE C CE1 1 
ATOM   4810 C CE2 . PHE C 3 169 ? 131.782 133.755 98.777  1.00 26.54 ? 151 PHE C CE2 1 
ATOM   4811 C CZ  . PHE C 3 169 ? 131.536 133.738 100.128 1.00 25.90 ? 151 PHE C CZ  1 
ATOM   4812 N N   . LEU C 3 170 ? 135.831 130.225 96.057  1.00 22.50 ? 152 LEU C N   1 
ATOM   4813 C CA  . LEU C 3 170 ? 136.688 130.108 94.883  1.00 27.41 ? 152 LEU C CA  1 
ATOM   4814 C C   . LEU C 3 170 ? 136.931 131.486 94.276  1.00 39.79 ? 152 LEU C C   1 
ATOM   4815 O O   . LEU C 3 170 ? 138.077 131.928 94.147  1.00 41.78 ? 152 LEU C O   1 
ATOM   4816 C CB  . LEU C 3 170 ? 136.042 129.175 93.852  1.00 29.97 ? 152 LEU C CB  1 
ATOM   4817 C CG  . LEU C 3 170 ? 136.336 127.679 93.959  1.00 33.35 ? 152 LEU C CG  1 
ATOM   4818 C CD1 . LEU C 3 170 ? 135.392 126.910 93.052  1.00 35.32 ? 152 LEU C CD1 1 
ATOM   4819 C CD2 . LEU C 3 170 ? 137.773 127.370 93.608  1.00 32.54 ? 152 LEU C CD2 1 
ATOM   4820 N N   . ASP C 3 171 ? 135.851 132.163 93.889  1.00 42.39 ? 153 ASP C N   1 
ATOM   4821 C CA  . ASP C 3 171 ? 135.870 133.560 93.476  1.00 39.50 ? 153 ASP C CA  1 
ATOM   4822 C C   . ASP C 3 171 ? 134.671 134.264 94.094  1.00 37.56 ? 153 ASP C C   1 
ATOM   4823 O O   . ASP C 3 171 ? 134.047 133.737 95.019  1.00 37.99 ? 153 ASP C O   1 
ATOM   4824 C CB  . ASP C 3 171 ? 135.844 133.701 91.953  1.00 43.11 ? 153 ASP C CB  1 
ATOM   4825 C CG  . ASP C 3 171 ? 136.637 132.625 91.252  1.00 46.65 ? 153 ASP C CG  1 
ATOM   4826 O OD1 . ASP C 3 171 ? 137.873 132.586 91.433  1.00 46.63 ? 153 ASP C OD1 1 
ATOM   4827 O OD2 . ASP C 3 171 ? 136.030 131.823 90.513  1.00 40.13 ? 153 ASP C OD2 1 
ATOM   4828 N N   . ASP C 3 172 ? 134.345 135.456 93.600  1.00 39.61 ? 154 ASP C N   1 
ATOM   4829 C CA  . ASP C 3 172 ? 133.196 136.194 94.104  1.00 39.46 ? 154 ASP C CA  1 
ATOM   4830 C C   . ASP C 3 172 ? 131.877 135.455 93.902  1.00 38.12 ? 154 ASP C C   1 
ATOM   4831 O O   . ASP C 3 172 ? 130.930 135.708 94.656  1.00 40.00 ? 154 ASP C O   1 
ATOM   4832 C CB  . ASP C 3 172 ? 133.128 137.560 93.415  1.00 45.05 ? 154 ASP C CB  1 
ATOM   4833 C CG  . ASP C 3 172 ? 132.378 138.593 94.228  1.00 46.89 ? 154 ASP C CG  1 
ATOM   4834 O OD1 . ASP C 3 172 ? 131.680 138.207 95.185  1.00 44.98 ? 154 ASP C OD1 1 
ATOM   4835 O OD2 . ASP C 3 172 ? 132.482 139.795 93.907  1.00 47.44 ? 154 ASP C OD2 1 
ATOM   4836 N N   . ASN C 3 173 ? 131.800 134.534 92.930  1.00 42.43 ? 155 ASN C N   1 
ATOM   4837 C CA  . ASN C 3 173 ? 130.533 133.972 92.472  1.00 42.41 ? 155 ASN C CA  1 
ATOM   4838 C C   . ASN C 3 173 ? 130.423 132.466 92.712  1.00 45.58 ? 155 ASN C C   1 
ATOM   4839 O O   . ASN C 3 173 ? 129.335 131.906 92.544  1.00 47.65 ? 155 ASN C O   1 
ATOM   4840 C CB  . ASN C 3 173 ? 130.343 134.289 90.984  1.00 39.44 ? 155 ASN C CB  1 
ATOM   4841 C CG  . ASN C 3 173 ? 128.952 133.956 90.478  1.00 43.45 ? 155 ASN C CG  1 
ATOM   4842 O OD1 . ASN C 3 173 ? 128.799 133.238 89.491  1.00 47.85 ? 155 ASN C OD1 1 
ATOM   4843 N ND2 . ASN C 3 173 ? 127.932 134.481 91.145  1.00 45.05 ? 155 ASN C ND2 1 
ATOM   4844 N N   . GLN C 3 174 ? 131.506 131.798 93.123  1.00 40.88 ? 156 GLN C N   1 
ATOM   4845 C CA  . GLN C 3 174 ? 131.498 130.356 93.349  1.00 34.97 ? 156 GLN C CA  1 
ATOM   4846 C C   . GLN C 3 174 ? 132.122 130.039 94.698  1.00 31.84 ? 156 GLN C C   1 
ATOM   4847 O O   . GLN C 3 174 ? 133.053 130.717 95.138  1.00 47.07 ? 156 GLN C O   1 
ATOM   4848 C CB  . GLN C 3 174 ? 132.253 129.572 92.258  1.00 34.59 ? 156 GLN C CB  1 
ATOM   4849 C CG  . GLN C 3 174 ? 132.101 130.069 90.826  1.00 39.57 ? 156 GLN C CG  1 
ATOM   4850 C CD  . GLN C 3 174 ? 133.160 129.491 89.908  1.00 39.33 ? 156 GLN C CD  1 
ATOM   4851 O OE1 . GLN C 3 174 ? 134.335 129.846 90.000  1.00 35.34 ? 156 GLN C OE1 1 
ATOM   4852 N NE2 . GLN C 3 174 ? 132.753 128.583 89.028  1.00 37.20 ? 156 GLN C NE2 1 
ATOM   4853 N N   . ILE C 3 175 ? 131.605 128.994 95.337  1.00 21.55 ? 157 ILE C N   1 
ATOM   4854 C CA  . ILE C 3 175 ? 132.052 128.552 96.653  1.00 17.76 ? 157 ILE C CA  1 
ATOM   4855 C C   . ILE C 3 175 ? 131.984 127.032 96.685  1.00 27.19 ? 157 ILE C C   1 
ATOM   4856 O O   . ILE C 3 175 ? 131.036 126.436 96.165  1.00 47.34 ? 157 ILE C O   1 
ATOM   4857 C CB  . ILE C 3 175 ? 131.197 129.173 97.783  1.00 22.97 ? 157 ILE C CB  1 
ATOM   4858 C CG1 . ILE C 3 175 ? 131.705 128.731 99.157  1.00 30.40 ? 157 ILE C CG1 1 
ATOM   4859 C CG2 . ILE C 3 175 ? 129.720 128.802 97.631  1.00 34.23 ? 157 ILE C CG2 1 
ATOM   4860 C CD1 . ILE C 3 175 ? 131.048 129.450 100.310 1.00 35.93 ? 157 ILE C CD1 1 
ATOM   4861 N N   . VAL C 3 176 ? 132.986 126.408 97.305  1.00 24.39 ? 158 VAL C N   1 
ATOM   4862 C CA  . VAL C 3 176 ? 133.059 124.958 97.455  1.00 22.41 ? 158 VAL C CA  1 
ATOM   4863 C C   . VAL C 3 176 ? 132.764 124.616 98.907  1.00 26.20 ? 158 VAL C C   1 
ATOM   4864 O O   . VAL C 3 176 ? 133.254 125.292 99.818  1.00 40.41 ? 158 VAL C O   1 
ATOM   4865 C CB  . VAL C 3 176 ? 134.426 124.391 97.021  1.00 15.83 ? 158 VAL C CB  1 
ATOM   4866 C CG1 . VAL C 3 176 ? 134.603 124.549 95.527  1.00 29.42 ? 158 VAL C CG1 1 
ATOM   4867 C CG2 . VAL C 3 176 ? 135.584 125.058 97.758  1.00 32.11 ? 158 VAL C CG2 1 
ATOM   4868 N N   . THR C 3 177 ? 131.957 123.579 99.115  1.00 23.96 ? 159 THR C N   1 
ATOM   4869 C CA  . THR C 3 177 ? 131.520 123.155 100.438 1.00 21.33 ? 159 THR C CA  1 
ATOM   4870 C C   . THR C 3 177 ? 131.805 121.674 100.625 1.00 32.40 ? 159 THR C C   1 
ATOM   4871 O O   . THR C 3 177 ? 131.729 120.896 99.671  1.00 47.92 ? 159 THR C O   1 
ATOM   4872 C CB  . THR C 3 177 ? 130.026 123.416 100.633 1.00 23.41 ? 159 THR C CB  1 
ATOM   4873 O OG1 . THR C 3 177 ? 129.305 122.942 99.491  1.00 38.10 ? 159 THR C OG1 1 
ATOM   4874 C CG2 . THR C 3 177 ? 129.762 124.895 100.822 1.00 29.78 ? 159 THR C CG2 1 
ATOM   4875 N N   . SER C 3 178 ? 132.137 121.296 101.857 1.00 15.24 ? 160 SER C N   1 
ATOM   4876 C CA  . SER C 3 178 ? 132.335 119.905 102.245 1.00 15.50 ? 160 SER C CA  1 
ATOM   4877 C C   . SER C 3 178 ? 131.373 119.598 103.380 1.00 25.74 ? 160 SER C C   1 
ATOM   4878 O O   . SER C 3 178 ? 131.464 120.205 104.452 1.00 30.22 ? 160 SER C O   1 
ATOM   4879 C CB  . SER C 3 178 ? 133.777 119.653 102.679 1.00 26.96 ? 160 SER C CB  1 
ATOM   4880 O OG  . SER C 3 178 ? 133.994 120.123 103.995 1.00 33.31 ? 160 SER C OG  1 
ATOM   4881 N N   . SER C 3 179 ? 130.473 118.650 103.153 1.00 37.29 ? 161 SER C N   1 
ATOM   4882 C CA  . SER C 3 179 ? 129.340 118.397 104.029 1.00 37.20 ? 161 SER C CA  1 
ATOM   4883 C C   . SER C 3 179 ? 129.552 117.112 104.821 1.00 37.78 ? 161 SER C C   1 
ATOM   4884 O O   . SER C 3 179 ? 130.512 116.369 104.607 1.00 44.98 ? 161 SER C O   1 
ATOM   4885 C CB  . SER C 3 179 ? 128.054 118.325 103.207 1.00 39.67 ? 161 SER C CB  1 
ATOM   4886 O OG  . SER C 3 179 ? 128.249 117.544 102.043 1.00 42.18 ? 161 SER C OG  1 
ATOM   4887 N N   . GLY C 3 180 ? 128.629 116.860 105.746 1.00 41.18 ? 162 GLY C N   1 
ATOM   4888 C CA  . GLY C 3 180 ? 128.661 115.668 106.569 1.00 45.17 ? 162 GLY C CA  1 
ATOM   4889 C C   . GLY C 3 180 ? 127.768 114.565 106.039 1.00 45.44 ? 162 GLY C C   1 
ATOM   4890 O O   . GLY C 3 180 ? 127.187 113.806 106.819 1.00 49.01 ? 162 GLY C O   1 
ATOM   4891 N N   . ASP C 3 181 ? 127.641 114.476 104.717 1.00 38.46 ? 163 ASP C N   1 
ATOM   4892 C CA  . ASP C 3 181 ? 126.926 113.396 104.048 1.00 42.29 ? 163 ASP C CA  1 
ATOM   4893 C C   . ASP C 3 181 ? 127.800 112.749 102.981 1.00 41.42 ? 163 ASP C C   1 
ATOM   4894 O O   . ASP C 3 181 ? 127.312 112.287 101.949 1.00 37.51 ? 163 ASP C O   1 
ATOM   4895 C CB  . ASP C 3 181 ? 125.618 113.898 103.443 1.00 43.69 ? 163 ASP C CB  1 
ATOM   4896 C CG  . ASP C 3 181 ? 125.836 114.876 102.314 1.00 38.15 ? 163 ASP C CG  1 
ATOM   4897 O OD1 . ASP C 3 181 ? 126.658 115.797 102.479 1.00 38.27 ? 163 ASP C OD1 1 
ATOM   4898 O OD2 . ASP C 3 181 ? 125.187 114.724 101.258 1.00 31.65 ? 163 ASP C OD2 1 
ATOM   4899 N N   . THR C 3 182 ? 129.112 112.716 103.222 1.00 39.81 ? 164 THR C N   1 
ATOM   4900 C CA  . THR C 3 182 ? 130.047 111.964 102.388 1.00 33.26 ? 164 THR C CA  1 
ATOM   4901 C C   . THR C 3 182 ? 130.109 112.532 100.968 1.00 36.97 ? 164 THR C C   1 
ATOM   4902 O O   . THR C 3 182 ? 130.068 111.801 99.978  1.00 44.47 ? 164 THR C O   1 
ATOM   4903 C CB  . THR C 3 182 ? 129.665 110.480 102.377 1.00 40.96 ? 164 THR C CB  1 
ATOM   4904 O OG1 . THR C 3 182 ? 129.394 110.051 103.716 1.00 48.22 ? 164 THR C OG1 1 
ATOM   4905 C CG2 . THR C 3 182 ? 130.776 109.617 101.797 1.00 40.36 ? 164 THR C CG2 1 
ATOM   4906 N N   . THR C 3 183 ? 130.210 113.857 100.871 1.00 31.22 ? 165 THR C N   1 
ATOM   4907 C CA  . THR C 3 183 ? 130.310 114.502 99.568  1.00 36.25 ? 165 THR C CA  1 
ATOM   4908 C C   . THR C 3 183 ? 130.656 115.972 99.744  1.00 33.12 ? 165 THR C C   1 
ATOM   4909 O O   . THR C 3 183 ? 130.365 116.581 100.776 1.00 35.63 ? 165 THR C O   1 
ATOM   4910 C CB  . THR C 3 183 ? 129.011 114.371 98.760  1.00 40.26 ? 165 THR C CB  1 
ATOM   4911 O OG1 . THR C 3 183 ? 129.182 114.993 97.483  1.00 41.31 ? 165 THR C OG1 1 
ATOM   4912 C CG2 . THR C 3 183 ? 127.842 115.036 99.477  1.00 36.94 ? 165 THR C CG2 1 
ATOM   4913 N N   . CYS C 3 184 ? 131.275 116.531 98.703  1.00 31.73 ? 166 CYS C N   1 
ATOM   4914 C CA  . CYS C 3 184 ? 131.528 117.958 98.581  1.00 32.10 ? 166 CYS C CA  1 
ATOM   4915 C C   . CYS C 3 184 ? 130.809 118.472 97.345  1.00 35.84 ? 166 CYS C C   1 
ATOM   4916 O O   . CYS C 3 184 ? 130.475 117.701 96.442  1.00 43.79 ? 166 CYS C O   1 
ATOM   4917 C CB  . CYS C 3 184 ? 133.024 118.273 98.467  1.00 25.00 ? 166 CYS C CB  1 
ATOM   4918 S SG  . CYS C 3 184 ? 134.020 117.728 99.855  1.00 25.05 ? 166 CYS C SG  1 
ATOM   4919 N N   . ALA C 3 185 ? 130.572 119.781 97.312  1.00 26.52 ? 167 ALA C N   1 
ATOM   4920 C CA  . ALA C 3 185 ? 129.865 120.416 96.211  1.00 27.24 ? 167 ALA C CA  1 
ATOM   4921 C C   . ALA C 3 185 ? 130.552 121.721 95.848  1.00 24.88 ? 167 ALA C C   1 
ATOM   4922 O O   . ALA C 3 185 ? 131.291 122.294 96.651  1.00 38.42 ? 167 ALA C O   1 
ATOM   4923 C CB  . ALA C 3 185 ? 128.398 120.683 96.564  1.00 32.49 ? 167 ALA C CB  1 
ATOM   4924 N N   . LEU C 3 186 ? 130.309 122.172 94.619  1.00 25.28 ? 168 LEU C N   1 
ATOM   4925 C CA  . LEU C 3 186 ? 130.759 123.469 94.131  1.00 24.82 ? 168 LEU C CA  1 
ATOM   4926 C C   . LEU C 3 186 ? 129.525 124.244 93.699  1.00 29.89 ? 168 LEU C C   1 
ATOM   4927 O O   . LEU C 3 186 ? 128.858 123.863 92.732  1.00 42.41 ? 168 LEU C O   1 
ATOM   4928 C CB  . LEU C 3 186 ? 131.750 123.301 92.971  1.00 23.95 ? 168 LEU C CB  1 
ATOM   4929 C CG  . LEU C 3 186 ? 132.509 124.493 92.363  1.00 29.51 ? 168 LEU C CG  1 
ATOM   4930 C CD1 . LEU C 3 186 ? 133.481 123.975 91.315  1.00 31.66 ? 168 LEU C CD1 1 
ATOM   4931 C CD2 . LEU C 3 186 ? 131.619 125.561 91.738  1.00 32.70 ? 168 LEU C CD2 1 
ATOM   4932 N N   . TRP C 3 187 ? 129.234 125.332 94.402  1.00 22.93 ? 169 TRP C N   1 
ATOM   4933 C CA  . TRP C 3 187 ? 128.016 126.099 94.201  1.00 27.61 ? 169 TRP C CA  1 
ATOM   4934 C C   . TRP C 3 187 ? 128.274 127.275 93.271  1.00 30.56 ? 169 TRP C C   1 
ATOM   4935 O O   . TRP C 3 187 ? 129.404 127.743 93.115  1.00 42.63 ? 169 TRP C O   1 
ATOM   4936 C CB  . TRP C 3 187 ? 127.462 126.617 95.532  1.00 28.22 ? 169 TRP C CB  1 
ATOM   4937 C CG  . TRP C 3 187 ? 127.189 125.554 96.541  1.00 30.02 ? 169 TRP C CG  1 
ATOM   4938 C CD1 . TRP C 3 187 ? 128.099 124.916 97.328  1.00 26.85 ? 169 TRP C CD1 1 
ATOM   4939 C CD2 . TRP C 3 187 ? 125.911 125.009 96.883  1.00 36.15 ? 169 TRP C CD2 1 
ATOM   4940 N NE1 . TRP C 3 187 ? 127.469 124.005 98.136  1.00 32.99 ? 169 TRP C NE1 1 
ATOM   4941 C CE2 . TRP C 3 187 ? 126.124 124.043 97.882  1.00 31.57 ? 169 TRP C CE2 1 
ATOM   4942 C CE3 . TRP C 3 187 ? 124.607 125.243 96.439  1.00 38.60 ? 169 TRP C CE3 1 
ATOM   4943 C CZ2 . TRP C 3 187 ? 125.085 123.312 98.444  1.00 31.90 ? 169 TRP C CZ2 1 
ATOM   4944 C CZ3 . TRP C 3 187 ? 123.577 124.518 96.998  1.00 35.37 ? 169 TRP C CZ3 1 
ATOM   4945 C CH2 . TRP C 3 187 ? 123.822 123.563 97.990  1.00 35.49 ? 169 TRP C CH2 1 
ATOM   4946 N N   . ASP C 3 188 ? 127.196 127.738 92.642  1.00 34.53 ? 170 ASP C N   1 
ATOM   4947 C CA  . ASP C 3 188 ? 127.171 129.004 91.920  1.00 39.48 ? 170 ASP C CA  1 
ATOM   4948 C C   . ASP C 3 188 ? 126.197 129.913 92.649  1.00 40.70 ? 170 ASP C C   1 
ATOM   4949 O O   . ASP C 3 188 ? 125.015 129.580 92.778  1.00 49.94 ? 170 ASP C O   1 
ATOM   4950 C CB  . ASP C 3 188 ? 126.756 128.807 90.460  1.00 44.69 ? 170 ASP C CB  1 
ATOM   4951 C CG  . ASP C 3 188 ? 126.943 130.057 89.625  1.00 43.72 ? 170 ASP C CG  1 
ATOM   4952 O OD1 . ASP C 3 188 ? 127.349 131.097 90.182  1.00 41.62 ? 170 ASP C OD1 1 
ATOM   4953 O OD2 . ASP C 3 188 ? 126.688 129.999 88.405  1.00 44.16 ? 170 ASP C OD2 1 
ATOM   4954 N N   . ILE C 3 189 ? 126.693 131.053 93.129  1.00 34.55 ? 171 ILE C N   1 
ATOM   4955 C CA  . ILE C 3 189 ? 125.916 131.862 94.065  1.00 38.92 ? 171 ILE C CA  1 
ATOM   4956 C C   . ILE C 3 189 ? 124.707 132.478 93.370  1.00 42.61 ? 171 ILE C C   1 
ATOM   4957 O O   . ILE C 3 189 ? 123.579 132.387 93.864  1.00 42.02 ? 171 ILE C O   1 
ATOM   4958 C CB  . ILE C 3 189 ? 126.806 132.935 94.719  1.00 41.29 ? 171 ILE C CB  1 
ATOM   4959 C CG1 . ILE C 3 189 ? 127.915 132.274 95.554  1.00 41.36 ? 171 ILE C CG1 1 
ATOM   4960 C CG2 . ILE C 3 189 ? 125.950 133.868 95.580  1.00 40.75 ? 171 ILE C CG2 1 
ATOM   4961 C CD1 . ILE C 3 189 ? 129.019 133.214 95.990  1.00 36.52 ? 171 ILE C CD1 1 
ATOM   4962 N N   . GLU C 3 190 ? 124.917 133.098 92.205  1.00 46.58 ? 172 GLU C N   1 
ATOM   4963 C CA  . GLU C 3 190 ? 123.830 133.825 91.551  1.00 45.12 ? 172 GLU C CA  1 
ATOM   4964 C C   . GLU C 3 190 ? 122.682 132.894 91.176  1.00 51.79 ? 172 GLU C C   1 
ATOM   4965 O O   . GLU C 3 190 ? 121.510 133.222 91.395  1.00 54.33 ? 172 GLU C O   1 
ATOM   4966 C CB  . GLU C 3 190 ? 124.353 134.558 90.313  1.00 44.94 ? 172 GLU C CB  1 
ATOM   4967 C CG  . GLU C 3 190 ? 123.390 135.587 89.721  1.00 48.38 ? 172 GLU C CG  1 
ATOM   4968 C CD  . GLU C 3 190 ? 123.123 136.763 90.643  1.00 51.54 ? 172 GLU C CD  1 
ATOM   4969 O OE1 . GLU C 3 190 ? 123.795 136.874 91.689  1.00 51.11 ? 172 GLU C OE1 1 
ATOM   4970 O OE2 . GLU C 3 190 ? 122.232 137.578 90.320  1.00 52.27 ? 172 GLU C OE2 1 
ATOM   4971 N N   . THR C 3 191 ? 122.995 131.726 90.614  1.00 49.41 ? 173 THR C N   1 
ATOM   4972 C CA  . THR C 3 191 ? 121.944 130.751 90.340  1.00 47.81 ? 173 THR C CA  1 
ATOM   4973 C C   . THR C 3 191 ? 121.418 130.147 91.635  1.00 45.70 ? 173 THR C C   1 
ATOM   4974 O O   . THR C 3 191 ? 120.226 129.839 91.748  1.00 47.35 ? 173 THR C O   1 
ATOM   4975 C CB  . THR C 3 191 ? 122.456 129.651 89.408  1.00 49.58 ? 173 THR C CB  1 
ATOM   4976 O OG1 . THR C 3 191 ? 123.363 128.800 90.118  1.00 46.74 ? 173 THR C OG1 1 
ATOM   4977 C CG2 . THR C 3 191 ? 123.155 130.248 88.190  1.00 44.44 ? 173 THR C CG2 1 
ATOM   4978 N N   . GLY C 3 192 ? 122.291 129.976 92.625  1.00 45.39 ? 174 GLY C N   1 
ATOM   4979 C CA  . GLY C 3 192 ? 121.878 129.450 93.909  1.00 44.63 ? 174 GLY C CA  1 
ATOM   4980 C C   . GLY C 3 192 ? 121.734 127.949 93.969  1.00 47.86 ? 174 GLY C C   1 
ATOM   4981 O O   . GLY C 3 192 ? 121.131 127.439 94.918  1.00 50.10 ? 174 GLY C O   1 
ATOM   4982 N N   . GLN C 3 193 ? 122.268 127.224 92.986  1.00 47.78 ? 175 GLN C N   1 
ATOM   4983 C CA  . GLN C 3 193 ? 122.163 125.773 92.931  1.00 49.78 ? 175 GLN C CA  1 
ATOM   4984 C C   . GLN C 3 193 ? 123.519 125.192 92.562  1.00 46.08 ? 175 GLN C C   1 
ATOM   4985 O O   . GLN C 3 193 ? 124.346 125.854 91.929  1.00 42.48 ? 175 GLN C O   1 
ATOM   4986 C CB  . GLN C 3 193 ? 121.102 125.294 91.919  1.00 47.37 ? 175 GLN C CB  1 
ATOM   4987 C CG  . GLN C 3 193 ? 121.095 126.006 90.553  1.00 46.74 ? 175 GLN C CG  1 
ATOM   4988 C CD  . GLN C 3 193 ? 119.755 125.916 89.841  1.00 48.05 ? 175 GLN C CD  1 
ATOM   4989 O OE1 . GLN C 3 193 ? 118.700 125.844 90.472  1.00 47.49 ? 175 GLN C OE1 1 
ATOM   4990 N NE2 . GLN C 3 193 ? 119.794 125.921 88.515  1.00 46.10 ? 175 GLN C NE2 1 
ATOM   4991 N N   . GLN C 3 194 ? 123.735 123.942 92.966  1.00 38.39 ? 176 GLN C N   1 
ATOM   4992 C CA  . GLN C 3 194 ? 125.012 123.286 92.735  1.00 34.23 ? 176 GLN C CA  1 
ATOM   4993 C C   . GLN C 3 194 ? 125.284 123.139 91.243  1.00 37.20 ? 176 GLN C C   1 
ATOM   4994 O O   . GLN C 3 194 ? 124.374 122.913 90.441  1.00 47.07 ? 176 GLN C O   1 
ATOM   4995 C CB  . GLN C 3 194 ? 125.027 121.909 93.396  1.00 29.80 ? 176 GLN C CB  1 
ATOM   4996 C CG  . GLN C 3 194 ? 124.883 121.947 94.901  1.00 38.61 ? 176 GLN C CG  1 
ATOM   4997 C CD  . GLN C 3 194 ? 124.923 120.568 95.524  1.00 39.47 ? 176 GLN C CD  1 
ATOM   4998 O OE1 . GLN C 3 194 ? 125.821 119.776 95.245  1.00 40.62 ? 176 GLN C OE1 1 
ATOM   4999 N NE2 . GLN C 3 194 ? 123.947 120.273 96.375  1.00 38.42 ? 176 GLN C NE2 1 
ATOM   5000 N N   . THR C 3 195 ? 126.561 123.281 90.879  1.00 27.94 ? 177 THR C N   1 
ATOM   5001 C CA  . THR C 3 195 ? 127.040 123.004 89.532  1.00 36.65 ? 177 THR C CA  1 
ATOM   5002 C C   . THR C 3 195 ? 127.953 121.791 89.461  1.00 36.67 ? 177 THR C C   1 
ATOM   5003 O O   . THR C 3 195 ? 128.256 121.335 88.353  1.00 40.70 ? 177 THR C O   1 
ATOM   5004 C CB  . THR C 3 195 ? 127.791 124.217 88.963  1.00 26.81 ? 177 THR C CB  1 
ATOM   5005 O OG1 . THR C 3 195 ? 129.049 124.361 89.631  1.00 23.45 ? 177 THR C OG1 1 
ATOM   5006 C CG2 . THR C 3 195 ? 126.974 125.483 89.140  1.00 33.52 ? 177 THR C CG2 1 
ATOM   5007 N N   . THR C 3 196 ? 128.406 121.265 90.595  1.00 32.90 ? 178 THR C N   1 
ATOM   5008 C CA  . THR C 3 196 ? 129.184 120.037 90.621  1.00 29.82 ? 178 THR C CA  1 
ATOM   5009 C C   . THR C 3 196 ? 128.979 119.383 91.977  1.00 29.64 ? 178 THR C C   1 
ATOM   5010 O O   . THR C 3 196 ? 128.724 120.072 92.967  1.00 37.85 ? 178 THR C O   1 
ATOM   5011 C CB  . THR C 3 196 ? 130.674 120.303 90.370  1.00 32.20 ? 178 THR C CB  1 
ATOM   5012 O OG1 . THR C 3 196 ? 130.831 121.095 89.186  1.00 33.32 ? 178 THR C OG1 1 
ATOM   5013 C CG2 . THR C 3 196 ? 131.436 119.000 90.202  1.00 33.59 ? 178 THR C CG2 1 
ATOM   5014 N N   . THR C 3 197 ? 129.072 118.056 92.010  1.00 23.75 ? 179 THR C N   1 
ATOM   5015 C CA  . THR C 3 197 ? 128.935 117.286 93.239  1.00 28.16 ? 179 THR C CA  1 
ATOM   5016 C C   . THR C 3 197 ? 130.049 116.255 93.280  1.00 31.49 ? 179 THR C C   1 
ATOM   5017 O O   . THR C 3 197 ? 130.098 115.356 92.435  1.00 36.82 ? 179 THR C O   1 
ATOM   5018 C CB  . THR C 3 197 ? 127.566 116.606 93.321  1.00 35.59 ? 179 THR C CB  1 
ATOM   5019 O OG1 . THR C 3 197 ? 126.549 117.522 92.901  1.00 41.20 ? 179 THR C OG1 1 
ATOM   5020 C CG2 . THR C 3 197 ? 127.271 116.160 94.744  1.00 28.45 ? 179 THR C CG2 1 
ATOM   5021 N N   . PHE C 3 198 ? 130.943 116.396 94.252  1.00 28.24 ? 180 PHE C N   1 
ATOM   5022 C CA  . PHE C 3 198 ? 132.040 115.461 94.454  1.00 36.00 ? 180 PHE C CA  1 
ATOM   5023 C C   . PHE C 3 198 ? 131.596 114.380 95.429  1.00 40.53 ? 180 PHE C C   1 
ATOM   5024 O O   . PHE C 3 198 ? 131.366 114.661 96.610  1.00 37.33 ? 180 PHE C O   1 
ATOM   5025 C CB  . PHE C 3 198 ? 133.266 116.193 94.989  1.00 35.16 ? 180 PHE C CB  1 
ATOM   5026 C CG  . PHE C 3 198 ? 133.583 117.459 94.253  1.00 33.80 ? 180 PHE C CG  1 
ATOM   5027 C CD1 . PHE C 3 198 ? 134.277 117.434 93.059  1.00 29.15 ? 180 PHE C CD1 1 
ATOM   5028 C CD2 . PHE C 3 198 ? 133.180 118.676 94.760  1.00 33.88 ? 180 PHE C CD2 1 
ATOM   5029 C CE1 . PHE C 3 198 ? 134.562 118.603 92.391  1.00 29.23 ? 180 PHE C CE1 1 
ATOM   5030 C CE2 . PHE C 3 198 ? 133.462 119.844 94.094  1.00 34.86 ? 180 PHE C CE2 1 
ATOM   5031 C CZ  . PHE C 3 198 ? 134.153 119.807 92.908  1.00 33.99 ? 180 PHE C CZ  1 
ATOM   5032 N N   . THR C 3 199 ? 131.478 113.147 94.935  1.00 42.52 ? 181 THR C N   1 
ATOM   5033 C CA  . THR C 3 199 ? 130.983 112.017 95.728  1.00 42.62 ? 181 THR C CA  1 
ATOM   5034 C C   . THR C 3 199 ? 131.896 110.820 95.453  1.00 42.63 ? 181 THR C C   1 
ATOM   5035 O O   . THR C 3 199 ? 131.629 110.000 94.572  1.00 42.55 ? 181 THR C O   1 
ATOM   5036 C CB  . THR C 3 199 ? 129.511 111.722 95.423  1.00 39.78 ? 181 THR C CB  1 
ATOM   5037 O OG1 . THR C 3 199 ? 129.094 110.556 96.143  1.00 40.50 ? 181 THR C OG1 1 
ATOM   5038 C CG2 . THR C 3 199 ? 129.230 111.524 93.916  1.00 35.07 ? 181 THR C CG2 1 
ATOM   5039 N N   . GLY C 3 200 ? 132.992 110.749 96.206  1.00 35.35 ? 182 GLY C N   1 
ATOM   5040 C CA  . GLY C 3 200 ? 133.930 109.644 96.134  1.00 32.05 ? 182 GLY C CA  1 
ATOM   5041 C C   . GLY C 3 200 ? 134.260 109.035 97.482  1.00 32.60 ? 182 GLY C C   1 
ATOM   5042 O O   . GLY C 3 200 ? 134.756 107.907 97.551  1.00 32.16 ? 182 GLY C O   1 
ATOM   5043 N N   . HIS C 3 201 ? 133.998 109.768 98.561  1.00 32.10 ? 183 HIS C N   1 
ATOM   5044 C CA  . HIS C 3 201 ? 134.328 109.296 99.894  1.00 33.05 ? 183 HIS C CA  1 
ATOM   5045 C C   . HIS C 3 201 ? 133.342 108.219 100.335 1.00 35.60 ? 183 HIS C C   1 
ATOM   5046 O O   . HIS C 3 201 ? 132.305 107.992 99.706  1.00 39.33 ? 183 HIS C O   1 
ATOM   5047 C CB  . HIS C 3 201 ? 134.329 110.459 100.887 1.00 36.40 ? 183 HIS C CB  1 
ATOM   5048 C CG  . HIS C 3 201 ? 135.622 111.212 100.935 1.00 34.75 ? 183 HIS C CG  1 
ATOM   5049 N ND1 . HIS C 3 201 ? 136.787 110.659 101.419 1.00 33.22 ? 183 HIS C ND1 1 
ATOM   5050 C CD2 . HIS C 3 201 ? 135.933 112.474 100.559 1.00 31.62 ? 183 HIS C CD2 1 
ATOM   5051 C CE1 . HIS C 3 201 ? 137.760 111.548 101.340 1.00 35.00 ? 183 HIS C CE1 1 
ATOM   5052 N NE2 . HIS C 3 201 ? 137.269 112.658 100.820 1.00 33.34 ? 183 HIS C NE2 1 
ATOM   5053 N N   . THR C 3 202 ? 133.690 107.543 101.433 1.00 36.64 ? 184 THR C N   1 
ATOM   5054 C CA  . THR C 3 202 ? 132.823 106.565 102.072 1.00 38.60 ? 184 THR C CA  1 
ATOM   5055 C C   . THR C 3 202 ? 132.465 106.931 103.503 1.00 39.08 ? 184 THR C C   1 
ATOM   5056 O O   . THR C 3 202 ? 131.538 106.330 104.059 1.00 36.82 ? 184 THR C O   1 
ATOM   5057 C CB  . THR C 3 202 ? 133.481 105.176 102.069 1.00 39.15 ? 184 THR C CB  1 
ATOM   5058 O OG1 . THR C 3 202 ? 134.414 105.082 103.151 1.00 42.52 ? 184 THR C OG1 1 
ATOM   5059 C CG2 . THR C 3 202 ? 134.210 104.928 100.757 1.00 38.15 ? 184 THR C CG2 1 
ATOM   5060 N N   . GLY C 3 203 ? 133.167 107.889 104.111 1.00 45.70 ? 185 GLY C N   1 
ATOM   5061 C CA  . GLY C 3 203 ? 132.864 108.375 105.436 1.00 43.04 ? 185 GLY C CA  1 
ATOM   5062 C C   . GLY C 3 203 ? 132.473 109.843 105.414 1.00 39.61 ? 185 GLY C C   1 
ATOM   5063 O O   . GLY C 3 203 ? 132.285 110.452 104.359 1.00 42.34 ? 185 GLY C O   1 
ATOM   5064 N N   . ASP C 3 204 ? 132.350 110.398 106.615 1.00 41.04 ? 186 ASP C N   1 
ATOM   5065 C CA  . ASP C 3 204 ? 132.035 111.813 106.756 1.00 42.59 ? 186 ASP C CA  1 
ATOM   5066 C C   . ASP C 3 204 ? 133.205 112.664 106.281 1.00 42.86 ? 186 ASP C C   1 
ATOM   5067 O O   . ASP C 3 204 ? 134.363 112.352 106.566 1.00 46.65 ? 186 ASP C O   1 
ATOM   5068 C CB  . ASP C 3 204 ? 131.716 112.130 108.215 1.00 42.65 ? 186 ASP C CB  1 
ATOM   5069 C CG  . ASP C 3 204 ? 130.662 113.194 108.357 1.00 45.58 ? 186 ASP C CG  1 
ATOM   5070 O OD1 . ASP C 3 204 ? 129.560 113.014 107.804 1.00 46.82 ? 186 ASP C OD1 1 
ATOM   5071 O OD2 . ASP C 3 204 ? 130.940 114.216 109.013 1.00 46.12 ? 186 ASP C OD2 1 
ATOM   5072 N N   . VAL C 3 205 ? 132.899 113.747 105.560 1.00 33.47 ? 187 VAL C N   1 
ATOM   5073 C CA  . VAL C 3 205 ? 133.913 114.695 105.105 1.00 29.30 ? 187 VAL C CA  1 
ATOM   5074 C C   . VAL C 3 205 ? 134.030 115.809 106.133 1.00 36.47 ? 187 VAL C C   1 
ATOM   5075 O O   . VAL C 3 205 ? 133.032 116.456 106.474 1.00 43.32 ? 187 VAL C O   1 
ATOM   5076 C CB  . VAL C 3 205 ? 133.568 115.261 103.719 1.00 30.87 ? 187 VAL C CB  1 
ATOM   5077 C CG1 . VAL C 3 205 ? 134.766 116.002 103.146 1.00 27.86 ? 187 VAL C CG1 1 
ATOM   5078 C CG2 . VAL C 3 205 ? 133.116 114.150 102.790 1.00 36.44 ? 187 VAL C CG2 1 
ATOM   5079 N N   . MET C 3 206 ? 135.252 116.047 106.613 1.00 37.24 ? 188 MET C N   1 
ATOM   5080 C CA  . MET C 3 206 ? 135.496 116.928 107.747 1.00 36.64 ? 188 MET C CA  1 
ATOM   5081 C C   . MET C 3 206 ? 136.254 118.199 107.403 1.00 39.55 ? 188 MET C C   1 
ATOM   5082 O O   . MET C 3 206 ? 136.210 119.149 108.187 1.00 38.75 ? 188 MET C O   1 
ATOM   5083 C CB  . MET C 3 206 ? 136.282 116.182 108.832 1.00 32.63 ? 188 MET C CB  1 
ATOM   5084 C CG  . MET C 3 206 ? 135.447 115.249 109.689 1.00 32.58 ? 188 MET C CG  1 
ATOM   5085 S SD  . MET C 3 206 ? 135.763 115.467 111.445 1.00 59.22 ? 188 MET C SD  1 
ATOM   5086 C CE  . MET C 3 206 ? 134.665 116.832 111.813 1.00 44.39 ? 188 MET C CE  1 
ATOM   5087 N N   . SER C 3 207 ? 136.952 118.250 106.270 1.00 33.39 ? 189 SER C N   1 
ATOM   5088 C CA  . SER C 3 207 ? 137.818 119.377 105.964 1.00 19.23 ? 189 SER C CA  1 
ATOM   5089 C C   . SER C 3 207 ? 137.949 119.549 104.458 1.00 25.32 ? 189 SER C C   1 
ATOM   5090 O O   . SER C 3 207 ? 137.427 118.750 103.677 1.00 36.73 ? 189 SER C O   1 
ATOM   5091 C CB  . SER C 3 207 ? 139.200 119.192 106.586 1.00 24.91 ? 189 SER C CB  1 
ATOM   5092 O OG  . SER C 3 207 ? 140.089 120.186 106.122 1.00 36.61 ? 189 SER C OG  1 
ATOM   5093 N N   . LEU C 3 208 ? 138.645 120.612 104.061 1.00 29.00 ? 190 LEU C N   1 
ATOM   5094 C CA  . LEU C 3 208 ? 138.802 120.962 102.657 1.00 27.33 ? 190 LEU C CA  1 
ATOM   5095 C C   . LEU C 3 208 ? 139.827 122.082 102.549 1.00 25.41 ? 190 LEU C C   1 
ATOM   5096 O O   . LEU C 3 208 ? 139.946 122.906 103.458 1.00 31.75 ? 190 LEU C O   1 
ATOM   5097 C CB  . LEU C 3 208 ? 137.455 121.380 102.055 1.00 15.07 ? 190 LEU C CB  1 
ATOM   5098 C CG  . LEU C 3 208 ? 137.420 122.123 100.719 1.00 16.16 ? 190 LEU C CG  1 
ATOM   5099 C CD1 . LEU C 3 208 ? 136.219 121.667 99.918  1.00 28.88 ? 190 LEU C CD1 1 
ATOM   5100 C CD2 . LEU C 3 208 ? 137.357 123.629 100.918 1.00 25.59 ? 190 LEU C CD2 1 
ATOM   5101 N N   . SER C 3 209 ? 140.565 122.108 101.440 1.00 18.29 ? 191 SER C N   1 
ATOM   5102 C CA  . SER C 3 209 ? 141.569 123.139 101.218 1.00 17.32 ? 191 SER C CA  1 
ATOM   5103 C C   . SER C 3 209 ? 141.783 123.342 99.727  1.00 22.12 ? 191 SER C C   1 
ATOM   5104 O O   . SER C 3 209 ? 142.160 122.409 99.016  1.00 23.34 ? 191 SER C O   1 
ATOM   5105 C CB  . SER C 3 209 ? 142.901 122.774 101.873 1.00 20.55 ? 191 SER C CB  1 
ATOM   5106 O OG  . SER C 3 209 ? 143.945 123.577 101.356 1.00 30.02 ? 191 SER C OG  1 
ATOM   5107 N N   . LEU C 3 210 ? 141.568 124.573 99.269  1.00 30.85 ? 192 LEU C N   1 
ATOM   5108 C CA  . LEU C 3 210 ? 141.795 124.939 97.882  1.00 31.96 ? 192 LEU C CA  1 
ATOM   5109 C C   . LEU C 3 210 ? 143.298 124.988 97.608  1.00 29.12 ? 192 LEU C C   1 
ATOM   5110 O O   . LEU C 3 210 ? 144.120 124.835 98.513  1.00 32.46 ? 192 LEU C O   1 
ATOM   5111 C CB  . LEU C 3 210 ? 141.130 126.281 97.579  1.00 29.81 ? 192 LEU C CB  1 
ATOM   5112 C CG  . LEU C 3 210 ? 139.601 126.277 97.500  1.00 27.64 ? 192 LEU C CG  1 
ATOM   5113 C CD1 . LEU C 3 210 ? 139.067 127.699 97.524  1.00 32.33 ? 192 LEU C CD1 1 
ATOM   5114 C CD2 . LEU C 3 210 ? 139.107 125.545 96.264  1.00 20.53 ? 192 LEU C CD2 1 
ATOM   5115 N N   . ALA C 3 211 ? 143.660 125.204 96.346  1.00 19.24 ? 193 ALA C N   1 
ATOM   5116 C CA  . ALA C 3 211 ? 145.042 125.311 95.906  1.00 21.13 ? 193 ALA C CA  1 
ATOM   5117 C C   . ALA C 3 211 ? 145.347 126.749 95.517  1.00 33.55 ? 193 ALA C C   1 
ATOM   5118 O O   . ALA C 3 211 ? 144.426 127.519 95.229  1.00 41.11 ? 193 ALA C O   1 
ATOM   5119 C CB  . ALA C 3 211 ? 145.324 124.394 94.710  1.00 21.13 ? 193 ALA C CB  1 
ATOM   5120 N N   . PRO C 3 212 ? 146.627 127.151 95.514  1.00 29.94 ? 194 PRO C N   1 
ATOM   5121 C CA  . PRO C 3 212 ? 146.941 128.526 95.082  1.00 34.30 ? 194 PRO C CA  1 
ATOM   5122 C C   . PRO C 3 212 ? 146.511 128.826 93.657  1.00 33.46 ? 194 PRO C C   1 
ATOM   5123 O O   . PRO C 3 212 ? 146.081 129.949 93.367  1.00 31.77 ? 194 PRO C O   1 
ATOM   5124 C CB  . PRO C 3 212 ? 148.466 128.601 95.240  1.00 33.52 ? 194 PRO C CB  1 
ATOM   5125 C CG  . PRO C 3 212 ? 148.808 127.529 96.199  1.00 33.20 ? 194 PRO C CG  1 
ATOM   5126 C CD  . PRO C 3 212 ? 147.845 126.428 95.921  1.00 24.10 ? 194 PRO C CD  1 
ATOM   5127 N N   . ASP C 3 213 ? 146.614 127.851 92.754  1.00 26.46 ? 195 ASP C N   1 
ATOM   5128 C CA  . ASP C 3 213 ? 146.188 128.053 91.375  1.00 27.25 ? 195 ASP C CA  1 
ATOM   5129 C C   . ASP C 3 213 ? 144.674 128.057 91.221  1.00 26.95 ? 195 ASP C C   1 
ATOM   5130 O O   . ASP C 3 213 ? 144.176 128.564 90.211  1.00 29.81 ? 195 ASP C O   1 
ATOM   5131 C CB  . ASP C 3 213 ? 146.791 126.976 90.466  1.00 37.88 ? 195 ASP C CB  1 
ATOM   5132 C CG  . ASP C 3 213 ? 146.390 125.570 90.870  1.00 36.87 ? 195 ASP C CG  1 
ATOM   5133 O OD1 . ASP C 3 213 ? 147.091 124.967 91.710  1.00 36.07 ? 195 ASP C OD1 1 
ATOM   5134 O OD2 . ASP C 3 213 ? 145.377 125.066 90.345  1.00 29.60 ? 195 ASP C OD2 1 
ATOM   5135 N N   . THR C 3 214 ? 143.936 127.512 92.188  1.00 30.64 ? 196 THR C N   1 
ATOM   5136 C CA  . THR C 3 214 ? 142.475 127.535 92.185  1.00 29.33 ? 196 THR C CA  1 
ATOM   5137 C C   . THR C 3 214 ? 141.920 126.765 90.984  1.00 33.32 ? 196 THR C C   1 
ATOM   5138 O O   . THR C 3 214 ? 140.976 127.189 90.316  1.00 37.64 ? 196 THR C O   1 
ATOM   5139 C CB  . THR C 3 214 ? 141.964 128.980 92.203  1.00 41.06 ? 196 THR C CB  1 
ATOM   5140 O OG1 . THR C 3 214 ? 142.772 129.762 93.090  1.00 35.72 ? 196 THR C OG1 1 
ATOM   5141 C CG2 . THR C 3 214 ? 140.520 129.042 92.669  1.00 38.30 ? 196 THR C CG2 1 
ATOM   5142 N N   . ARG C 3 215 ? 142.538 125.611 90.722  1.00 38.96 ? 197 ARG C N   1 
ATOM   5143 C CA  . ARG C 3 215 ? 142.084 124.694 89.682  1.00 34.20 ? 197 ARG C CA  1 
ATOM   5144 C C   . ARG C 3 215 ? 141.899 123.270 90.176  1.00 32.19 ? 197 ARG C C   1 
ATOM   5145 O O   . ARG C 3 215 ? 141.264 122.479 89.472  1.00 39.33 ? 197 ARG C O   1 
ATOM   5146 C CB  . ARG C 3 215 ? 143.069 124.686 88.504  1.00 32.34 ? 197 ARG C CB  1 
ATOM   5147 N N   . LEU C 3 216 ? 142.421 122.911 91.346  1.00 29.45 ? 198 LEU C N   1 
ATOM   5148 C CA  . LEU C 3 216 ? 142.203 121.596 91.928  1.00 30.53 ? 198 LEU C CA  1 
ATOM   5149 C C   . LEU C 3 216 ? 142.408 121.708 93.430  1.00 27.51 ? 198 LEU C C   1 
ATOM   5150 O O   . LEU C 3 216 ? 143.333 122.389 93.876  1.00 30.08 ? 198 LEU C O   1 
ATOM   5151 C CB  . LEU C 3 216 ? 143.149 120.553 91.311  1.00 21.65 ? 198 LEU C CB  1 
ATOM   5152 C CG  . LEU C 3 216 ? 144.593 120.421 91.798  1.00 28.85 ? 198 LEU C CG  1 
ATOM   5153 C CD1 . LEU C 3 216 ? 145.237 119.220 91.135  1.00 30.35 ? 198 LEU C CD1 1 
ATOM   5154 C CD2 . LEU C 3 216 ? 145.389 121.680 91.511  1.00 38.84 ? 198 LEU C CD2 1 
ATOM   5155 N N   . PHE C 3 217 ? 141.544 121.047 94.199  1.00 27.01 ? 199 PHE C N   1 
ATOM   5156 C CA  . PHE C 3 217 ? 141.577 121.107 95.654  1.00 24.81 ? 199 PHE C CA  1 
ATOM   5157 C C   . PHE C 3 217 ? 141.632 119.700 96.229  1.00 26.98 ? 199 PHE C C   1 
ATOM   5158 O O   . PHE C 3 217 ? 141.570 118.707 95.501  1.00 42.58 ? 199 PHE C O   1 
ATOM   5159 C CB  . PHE C 3 217 ? 140.364 121.871 96.208  1.00 20.83 ? 199 PHE C CB  1 
ATOM   5160 C CG  . PHE C 3 217 ? 139.071 121.106 96.151  1.00 27.34 ? 199 PHE C CG  1 
ATOM   5161 C CD1 . PHE C 3 217 ? 138.338 121.048 94.982  1.00 31.16 ? 199 PHE C CD1 1 
ATOM   5162 C CD2 . PHE C 3 217 ? 138.573 120.473 97.275  1.00 32.36 ? 199 PHE C CD2 1 
ATOM   5163 C CE1 . PHE C 3 217 ? 137.145 120.357 94.931  1.00 33.48 ? 199 PHE C CE1 1 
ATOM   5164 C CE2 . PHE C 3 217 ? 137.381 119.780 97.226  1.00 25.00 ? 199 PHE C CE2 1 
ATOM   5165 C CZ  . PHE C 3 217 ? 136.668 119.723 96.055  1.00 26.65 ? 199 PHE C CZ  1 
ATOM   5166 N N   . VAL C 3 218 ? 141.764 119.634 97.553  1.00 18.62 ? 200 VAL C N   1 
ATOM   5167 C CA  . VAL C 3 218 ? 141.861 118.380 98.289  1.00 22.30 ? 200 VAL C CA  1 
ATOM   5168 C C   . VAL C 3 218 ? 140.839 118.400 99.413  1.00 25.10 ? 200 VAL C C   1 
ATOM   5169 O O   . VAL C 3 218 ? 140.334 119.458 99.800  1.00 44.49 ? 200 VAL C O   1 
ATOM   5170 C CB  . VAL C 3 218 ? 143.281 118.130 98.850  1.00 27.00 ? 200 VAL C CB  1 
ATOM   5171 C CG1 . VAL C 3 218 ? 144.277 117.936 97.716  1.00 29.55 ? 200 VAL C CG1 1 
ATOM   5172 C CG2 . VAL C 3 218 ? 143.725 119.270 99.771  1.00 28.61 ? 200 VAL C CG2 1 
ATOM   5173 N N   . SER C 3 219 ? 140.532 117.215 99.935  1.00 6.67  ? 201 SER C N   1 
ATOM   5174 C CA  . SER C 3 219 ? 139.541 117.056 100.986 1.00 16.20 ? 201 SER C CA  1 
ATOM   5175 C C   . SER C 3 219 ? 139.997 115.989 101.969 1.00 27.32 ? 201 SER C C   1 
ATOM   5176 O O   . SER C 3 219 ? 140.869 115.172 101.664 1.00 32.65 ? 201 SER C O   1 
ATOM   5177 C CB  . SER C 3 219 ? 138.176 116.678 100.409 1.00 26.99 ? 201 SER C CB  1 
ATOM   5178 O OG  . SER C 3 219 ? 137.271 116.329 101.440 1.00 29.22 ? 201 SER C OG  1 
ATOM   5179 N N   . GLY C 3 220 ? 139.397 116.016 103.156 1.00 27.97 ? 202 GLY C N   1 
ATOM   5180 C CA  . GLY C 3 220 ? 139.693 115.063 104.208 1.00 29.50 ? 202 GLY C CA  1 
ATOM   5181 C C   . GLY C 3 220 ? 138.426 114.510 104.819 1.00 32.05 ? 202 GLY C C   1 
ATOM   5182 O O   . GLY C 3 220 ? 137.472 115.262 105.039 1.00 38.32 ? 202 GLY C O   1 
ATOM   5183 N N   . ALA C 3 221 ? 138.397 113.209 105.096 1.00 29.57 ? 203 ALA C N   1 
ATOM   5184 C CA  . ALA C 3 221 ? 137.201 112.532 105.578 1.00 35.17 ? 203 ALA C CA  1 
ATOM   5185 C C   . ALA C 3 221 ? 137.527 111.670 106.794 1.00 31.54 ? 203 ALA C C   1 
ATOM   5186 O O   . ALA C 3 221 ? 138.686 111.510 107.183 1.00 29.42 ? 203 ALA C O   1 
ATOM   5187 C CB  . ALA C 3 221 ? 136.573 111.702 104.457 1.00 31.91 ? 203 ALA C CB  1 
ATOM   5188 N N   . CYS C 3 222 ? 136.477 111.110 107.395 1.00 41.01 ? 204 CYS C N   1 
ATOM   5189 C CA  . CYS C 3 222 ? 136.611 110.270 108.576 1.00 42.38 ? 204 CYS C CA  1 
ATOM   5190 C C   . CYS C 3 222 ? 137.038 108.844 108.258 1.00 41.94 ? 204 CYS C C   1 
ATOM   5191 O O   . CYS C 3 222 ? 137.283 108.070 109.189 1.00 40.38 ? 204 CYS C O   1 
ATOM   5192 C CB  . CYS C 3 222 ? 135.294 110.232 109.358 1.00 42.82 ? 204 CYS C CB  1 
ATOM   5193 S SG  . CYS C 3 222 ? 134.981 111.689 110.374 1.00 38.39 ? 204 CYS C SG  1 
ATOM   5194 N N   . ASP C 3 223 ? 137.135 108.474 106.979 1.00 37.29 ? 205 ASP C N   1 
ATOM   5195 C CA  . ASP C 3 223 ? 137.599 107.150 106.587 1.00 35.33 ? 205 ASP C CA  1 
ATOM   5196 C C   . ASP C 3 223 ? 139.121 107.062 106.499 1.00 38.58 ? 205 ASP C C   1 
ATOM   5197 O O   . ASP C 3 223 ? 139.640 106.116 105.896 1.00 47.52 ? 205 ASP C O   1 
ATOM   5198 C CB  . ASP C 3 223 ? 136.961 106.732 105.254 1.00 33.06 ? 205 ASP C CB  1 
ATOM   5199 C CG  . ASP C 3 223 ? 137.225 107.716 104.122 1.00 34.95 ? 205 ASP C CG  1 
ATOM   5200 O OD1 . ASP C 3 223 ? 138.393 108.078 103.880 1.00 38.17 ? 205 ASP C OD1 1 
ATOM   5201 O OD2 . ASP C 3 223 ? 136.248 108.130 103.466 1.00 36.44 ? 205 ASP C OD2 1 
ATOM   5202 N N   . ALA C 3 224 ? 139.843 108.018 107.089 1.00 24.84 ? 206 ALA C N   1 
ATOM   5203 C CA  . ALA C 3 224 ? 141.304 108.009 107.100 1.00 27.38 ? 206 ALA C CA  1 
ATOM   5204 C C   . ALA C 3 224 ? 141.869 108.027 105.683 1.00 29.63 ? 206 ALA C C   1 
ATOM   5205 O O   . ALA C 3 224 ? 142.762 107.250 105.341 1.00 33.37 ? 206 ALA C O   1 
ATOM   5206 C CB  . ALA C 3 224 ? 141.841 106.807 107.881 1.00 33.58 ? 206 ALA C CB  1 
ATOM   5207 N N   . SER C 3 225 ? 141.337 108.917 104.849 1.00 28.27 ? 207 SER C N   1 
ATOM   5208 C CA  . SER C 3 225 ? 141.800 109.051 103.476 1.00 36.29 ? 207 SER C CA  1 
ATOM   5209 C C   . SER C 3 225 ? 141.534 110.470 102.999 1.00 30.96 ? 207 SER C C   1 
ATOM   5210 O O   . SER C 3 225 ? 140.521 111.072 103.361 1.00 30.00 ? 207 SER C O   1 
ATOM   5211 C CB  . SER C 3 225 ? 141.107 108.045 102.551 1.00 37.80 ? 207 SER C CB  1 
ATOM   5212 O OG  . SER C 3 225 ? 139.917 108.587 102.008 1.00 30.37 ? 207 SER C OG  1 
ATOM   5213 N N   . ALA C 3 226 ? 142.455 110.993 102.194 1.00 25.06 ? 208 ALA C N   1 
ATOM   5214 C CA  . ALA C 3 226 ? 142.330 112.302 101.573 1.00 20.65 ? 208 ALA C CA  1 
ATOM   5215 C C   . ALA C 3 226 ? 142.332 112.148 100.060 1.00 28.00 ? 208 ALA C C   1 
ATOM   5216 O O   . ALA C 3 226 ? 143.092 111.353 99.502  1.00 39.65 ? 208 ALA C O   1 
ATOM   5217 C CB  . ALA C 3 226 ? 143.468 113.228 102.005 1.00 24.03 ? 208 ALA C CB  1 
ATOM   5218 N N   . LYS C 3 227 ? 141.471 112.921 99.402  1.00 27.97 ? 209 LYS C N   1 
ATOM   5219 C CA  . LYS C 3 227 ? 141.243 112.824 97.968  1.00 32.83 ? 209 LYS C CA  1 
ATOM   5220 C C   . LYS C 3 227 ? 141.568 114.152 97.306  1.00 29.77 ? 209 LYS C C   1 
ATOM   5221 O O   . LYS C 3 227 ? 141.221 115.218 97.819  1.00 40.07 ? 209 LYS C O   1 
ATOM   5222 C CB  . LYS C 3 227 ? 139.790 112.435 97.672  1.00 34.97 ? 209 LYS C CB  1 
ATOM   5223 C CG  . LYS C 3 227 ? 139.439 111.016 98.081  1.00 36.27 ? 209 LYS C CG  1 
ATOM   5224 C CD  . LYS C 3 227 ? 138.186 110.526 97.371  1.00 36.30 ? 209 LYS C CD  1 
ATOM   5225 C CE  . LYS C 3 227 ? 137.726 109.155 97.854  1.00 32.41 ? 209 LYS C CE  1 
ATOM   5226 N NZ  . LYS C 3 227 ? 138.815 108.290 98.384  1.00 35.12 ? 209 LYS C NZ  1 
ATOM   5227 N N   . LEU C 3 228 ? 142.230 114.075 96.155  1.00 20.83 ? 210 LEU C N   1 
ATOM   5228 C CA  . LEU C 3 228 ? 142.618 115.243 95.369  1.00 28.76 ? 210 LEU C CA  1 
ATOM   5229 C C   . LEU C 3 228 ? 141.604 115.398 94.245  1.00 33.22 ? 210 LEU C C   1 
ATOM   5230 O O   . LEU C 3 228 ? 141.648 114.655 93.259  1.00 41.55 ? 210 LEU C O   1 
ATOM   5231 C CB  . LEU C 3 228 ? 144.036 115.079 94.822  1.00 35.84 ? 210 LEU C CB  1 
ATOM   5232 C CG  . LEU C 3 228 ? 144.568 116.096 93.805  1.00 33.00 ? 210 LEU C CG  1 
ATOM   5233 C CD1 . LEU C 3 228 ? 144.851 117.432 94.464  1.00 32.28 ? 210 LEU C CD1 1 
ATOM   5234 C CD2 . LEU C 3 228 ? 145.809 115.546 93.134  1.00 30.38 ? 210 LEU C CD2 1 
ATOM   5235 N N   . TRP C 3 229 ? 140.702 116.363 94.388  1.00 25.34 ? 211 TRP C N   1 
ATOM   5236 C CA  . TRP C 3 229 ? 139.634 116.548 93.423  1.00 27.20 ? 211 TRP C CA  1 
ATOM   5237 C C   . TRP C 3 229 ? 140.056 117.517 92.325  1.00 26.98 ? 211 TRP C C   1 
ATOM   5238 O O   . TRP C 3 229 ? 141.137 118.102 92.357  1.00 38.92 ? 211 TRP C O   1 
ATOM   5239 C CB  . TRP C 3 229 ? 138.366 117.045 94.106  1.00 31.92 ? 211 TRP C CB  1 
ATOM   5240 C CG  . TRP C 3 229 ? 137.870 116.119 95.136  1.00 31.08 ? 211 TRP C CG  1 
ATOM   5241 C CD1 . TRP C 3 229 ? 138.213 116.090 96.453  1.00 32.78 ? 211 TRP C CD1 1 
ATOM   5242 C CD2 . TRP C 3 229 ? 136.995 115.015 94.923  1.00 30.04 ? 211 TRP C CD2 1 
ATOM   5243 N NE1 . TRP C 3 229 ? 137.564 115.061 97.087  1.00 33.40 ? 211 TRP C NE1 1 
ATOM   5244 C CE2 . TRP C 3 229 ? 136.814 114.381 96.164  1.00 31.37 ? 211 TRP C CE2 1 
ATOM   5245 C CE3 . TRP C 3 229 ? 136.335 114.509 93.802  1.00 32.42 ? 211 TRP C CE3 1 
ATOM   5246 C CZ2 . TRP C 3 229 ? 135.998 113.271 96.317  1.00 37.71 ? 211 TRP C CZ2 1 
ATOM   5247 C CZ3 . TRP C 3 229 ? 135.525 113.410 93.955  1.00 44.41 ? 211 TRP C CZ3 1 
ATOM   5248 C CH2 . TRP C 3 229 ? 135.364 112.801 95.202  1.00 46.09 ? 211 TRP C CH2 1 
ATOM   5249 N N   . ASP C 3 230 ? 139.185 117.669 91.331  1.00 37.55 ? 212 ASP C N   1 
ATOM   5250 C CA  . ASP C 3 230 ? 139.338 118.646 90.264  1.00 38.12 ? 212 ASP C CA  1 
ATOM   5251 C C   . ASP C 3 230 ? 138.030 119.408 90.128  1.00 40.71 ? 212 ASP C C   1 
ATOM   5252 O O   . ASP C 3 230 ? 136.951 118.810 90.163  1.00 45.20 ? 212 ASP C O   1 
ATOM   5253 C CB  . ASP C 3 230 ? 139.702 117.970 88.940  1.00 42.81 ? 212 ASP C CB  1 
ATOM   5254 C CG  . ASP C 3 230 ? 140.098 118.961 87.864  1.00 44.36 ? 212 ASP C CG  1 
ATOM   5255 O OD1 . ASP C 3 230 ? 140.051 120.182 88.119  1.00 43.34 ? 212 ASP C OD1 1 
ATOM   5256 O OD2 . ASP C 3 230 ? 140.463 118.516 86.757  1.00 44.39 ? 212 ASP C OD2 1 
ATOM   5257 N N   . VAL C 3 231 ? 138.128 120.729 89.970  1.00 37.10 ? 213 VAL C N   1 
ATOM   5258 C CA  . VAL C 3 231 ? 136.929 121.563 89.940  1.00 44.13 ? 213 VAL C CA  1 
ATOM   5259 C C   . VAL C 3 231 ? 136.327 121.693 88.544  1.00 48.10 ? 213 VAL C C   1 
ATOM   5260 O O   . VAL C 3 231 ? 135.158 122.085 88.422  1.00 48.78 ? 213 VAL C O   1 
ATOM   5261 C CB  . VAL C 3 231 ? 137.195 122.973 90.505  1.00 37.24 ? 213 VAL C CB  1 
ATOM   5262 C CG1 . VAL C 3 231 ? 137.372 122.910 92.014  1.00 31.50 ? 213 VAL C CG1 1 
ATOM   5263 C CG2 . VAL C 3 231 ? 138.398 123.640 89.844  1.00 40.86 ? 213 VAL C CG2 1 
ATOM   5264 N N   . ARG C 3 232 ? 137.081 121.375 87.491  1.00 53.76 ? 214 ARG C N   1 
ATOM   5265 C CA  . ARG C 3 232 ? 136.540 121.465 86.139  1.00 51.63 ? 214 ARG C CA  1 
ATOM   5266 C C   . ARG C 3 232 ? 135.656 120.262 85.824  1.00 49.33 ? 214 ARG C C   1 
ATOM   5267 O O   . ARG C 3 232 ? 134.461 120.411 85.547  1.00 51.95 ? 214 ARG C O   1 
ATOM   5268 C CB  . ARG C 3 232 ? 137.676 121.583 85.115  1.00 49.66 ? 214 ARG C CB  1 
ATOM   5269 C CG  . ARG C 3 232 ? 138.767 122.590 85.471  1.00 49.82 ? 214 ARG C CG  1 
ATOM   5270 C CD  . ARG C 3 232 ? 138.207 123.991 85.640  1.00 51.47 ? 214 ARG C CD  1 
ATOM   5271 N NE  . ARG C 3 232 ? 139.263 124.993 85.733  1.00 53.13 ? 214 ARG C NE  1 
ATOM   5272 C CZ  . ARG C 3 232 ? 139.081 126.261 86.081  1.00 55.32 ? 214 ARG C CZ  1 
ATOM   5273 N NH1 . ARG C 3 232 ? 137.883 126.734 86.392  1.00 56.65 ? 214 ARG C NH1 1 
ATOM   5274 N NH2 . ARG C 3 232 ? 140.130 127.078 86.123  1.00 51.12 ? 214 ARG C NH2 1 
ATOM   5275 N N   . GLU C 3 233 ? 136.226 119.057 85.870  1.00 54.57 ? 215 GLU C N   1 
ATOM   5276 C CA  . GLU C 3 233 ? 135.451 117.852 85.595  1.00 58.11 ? 215 GLU C CA  1 
ATOM   5277 C C   . GLU C 3 233 ? 134.603 117.455 86.797  1.00 57.43 ? 215 GLU C C   1 
ATOM   5278 O O   . GLU C 3 233 ? 133.375 117.352 86.698  1.00 58.36 ? 215 GLU C O   1 
ATOM   5279 C CB  . GLU C 3 233 ? 136.380 116.702 85.196  1.00 58.35 ? 215 GLU C CB  1 
ATOM   5280 C CG  . GLU C 3 233 ? 136.996 116.845 83.809  1.00 58.96 ? 215 GLU C CG  1 
ATOM   5281 C CD  . GLU C 3 233 ? 138.206 117.761 83.776  1.00 61.57 ? 215 GLU C CD  1 
ATOM   5282 O OE1 . GLU C 3 233 ? 138.608 118.271 84.841  1.00 59.29 ? 215 GLU C OE1 1 
ATOM   5283 O OE2 . GLU C 3 233 ? 138.757 117.972 82.675  1.00 61.52 ? 215 GLU C OE2 1 
ATOM   5284 N N   . GLY C 3 234 ? 135.247 117.225 87.938  1.00 50.32 ? 216 GLY C N   1 
ATOM   5285 C CA  . GLY C 3 234 ? 134.571 116.775 89.139  1.00 50.92 ? 216 GLY C CA  1 
ATOM   5286 C C   . GLY C 3 234 ? 134.833 115.314 89.431  1.00 47.70 ? 216 GLY C C   1 
ATOM   5287 O O   . GLY C 3 234 ? 133.994 114.633 90.028  1.00 48.28 ? 216 GLY C O   1 
ATOM   5288 N N   . MET C 3 235 ? 135.999 114.826 89.013  1.00 47.07 ? 217 MET C N   1 
ATOM   5289 C CA  . MET C 3 235 ? 136.404 113.440 89.194  1.00 54.10 ? 217 MET C CA  1 
ATOM   5290 C C   . MET C 3 235 ? 137.640 113.389 90.079  1.00 52.39 ? 217 MET C C   1 
ATOM   5291 O O   . MET C 3 235 ? 138.580 114.166 89.894  1.00 48.00 ? 217 MET C O   1 
ATOM   5292 C CB  . MET C 3 235 ? 136.686 112.745 87.845  1.00 47.67 ? 217 MET C CB  1 
ATOM   5293 C CG  . MET C 3 235 ? 137.644 113.474 86.884  1.00 48.82 ? 217 MET C CG  1 
ATOM   5294 S SD  . MET C 3 235 ? 139.410 113.171 87.141  1.00 59.91 ? 217 MET C SD  1 
ATOM   5295 C CE  . MET C 3 235 ? 139.542 111.393 86.977  1.00 48.49 ? 217 MET C CE  1 
ATOM   5296 N N   . CYS C 3 236 ? 137.619 112.487 91.056  1.00 45.32 ? 218 CYS C N   1 
ATOM   5297 C CA  . CYS C 3 236 ? 138.781 112.280 91.906  1.00 37.18 ? 218 CYS C CA  1 
ATOM   5298 C C   . CYS C 3 236 ? 139.971 111.822 91.074  1.00 44.28 ? 218 CYS C C   1 
ATOM   5299 O O   . CYS C 3 236 ? 139.859 110.908 90.254  1.00 52.52 ? 218 CYS C O   1 
ATOM   5300 C CB  . CYS C 3 236 ? 138.474 111.241 92.980  1.00 34.78 ? 218 CYS C CB  1 
ATOM   5301 S SG  . CYS C 3 236 ? 139.896 110.819 94.001  1.00 49.97 ? 218 CYS C SG  1 
ATOM   5302 N N   . ARG C 3 237 ? 141.119 112.460 91.297  1.00 33.52 ? 219 ARG C N   1 
ATOM   5303 C CA  . ARG C 3 237 ? 142.352 112.128 90.594  1.00 37.70 ? 219 ARG C CA  1 
ATOM   5304 C C   . ARG C 3 237 ? 143.256 111.203 91.392  1.00 36.54 ? 219 ARG C C   1 
ATOM   5305 O O   . ARG C 3 237 ? 143.789 110.241 90.836  1.00 40.98 ? 219 ARG C O   1 
ATOM   5306 C CB  . ARG C 3 237 ? 143.129 113.400 90.233  1.00 38.76 ? 219 ARG C CB  1 
ATOM   5307 C CG  . ARG C 3 237 ? 142.278 114.550 89.731  1.00 39.74 ? 219 ARG C CG  1 
ATOM   5308 C CD  . ARG C 3 237 ? 143.135 115.718 89.267  1.00 43.41 ? 219 ARG C CD  1 
ATOM   5309 N NE  . ARG C 3 237 ? 143.812 115.451 88.001  1.00 40.25 ? 219 ARG C NE  1 
ATOM   5310 C CZ  . ARG C 3 237 ? 145.050 114.987 87.864  1.00 44.83 ? 219 ARG C CZ  1 
ATOM   5311 N NH1 . ARG C 3 237 ? 145.811 114.699 88.910  1.00 45.55 ? 219 ARG C NH1 1 
ATOM   5312 N NH2 . ARG C 3 237 ? 145.540 114.806 86.642  1.00 46.30 ? 219 ARG C NH2 1 
ATOM   5313 N N   . GLN C 3 238 ? 143.461 111.484 92.677  1.00 29.29 ? 220 GLN C N   1 
ATOM   5314 C CA  . GLN C 3 238 ? 144.371 110.713 93.510  1.00 34.75 ? 220 GLN C CA  1 
ATOM   5315 C C   . GLN C 3 238 ? 143.783 110.565 94.904  1.00 36.13 ? 220 GLN C C   1 
ATOM   5316 O O   . GLN C 3 238 ? 143.017 111.415 95.364  1.00 42.07 ? 220 GLN C O   1 
ATOM   5317 C CB  . GLN C 3 238 ? 145.751 111.377 93.593  1.00 36.61 ? 220 GLN C CB  1 
ATOM   5318 C CG  . GLN C 3 238 ? 146.550 111.330 92.292  1.00 43.73 ? 220 GLN C CG  1 
ATOM   5319 C CD  . GLN C 3 238 ? 147.778 112.237 92.284  1.00 38.35 ? 220 GLN C CD  1 
ATOM   5320 O OE1 . GLN C 3 238 ? 148.185 112.717 91.228  1.00 33.72 ? 220 GLN C OE1 1 
ATOM   5321 N NE2 . GLN C 3 238 ? 148.383 112.458 93.448  1.00 39.89 ? 220 GLN C NE2 1 
ATOM   5322 N N   . THR C 3 239 ? 144.151 109.472 95.568  1.00 29.45 ? 221 THR C N   1 
ATOM   5323 C CA  . THR C 3 239 ? 143.749 109.194 96.938  1.00 25.92 ? 221 THR C CA  1 
ATOM   5324 C C   . THR C 3 239 ? 144.976 108.800 97.744  1.00 32.78 ? 221 THR C C   1 
ATOM   5325 O O   . THR C 3 239 ? 145.839 108.067 97.254  1.00 44.11 ? 221 THR C O   1 
ATOM   5326 C CB  . THR C 3 239 ? 142.706 108.077 97.003  1.00 32.52 ? 221 THR C CB  1 
ATOM   5327 O OG1 . THR C 3 239 ? 141.660 108.342 96.062  1.00 37.98 ? 221 THR C OG1 1 
ATOM   5328 C CG2 . THR C 3 239 ? 142.112 107.975 98.401  1.00 27.34 ? 221 THR C CG2 1 
ATOM   5329 N N   . PHE C 3 240 ? 145.044 109.295 98.978  1.00 32.07 ? 222 PHE C N   1 
ATOM   5330 C CA  . PHE C 3 240 ? 146.159 109.048 99.882  1.00 35.05 ? 222 PHE C CA  1 
ATOM   5331 C C   . PHE C 3 240 ? 145.632 108.419 101.161 1.00 33.95 ? 222 PHE C C   1 
ATOM   5332 O O   . PHE C 3 240 ? 144.875 109.055 101.901 1.00 21.58 ? 222 PHE C O   1 
ATOM   5333 C CB  . PHE C 3 240 ? 146.905 110.343 100.205 1.00 30.19 ? 222 PHE C CB  1 
ATOM   5334 C CG  . PHE C 3 240 ? 147.287 111.142 98.995  1.00 23.92 ? 222 PHE C CG  1 
ATOM   5335 C CD1 . PHE C 3 240 ? 146.419 112.073 98.460  1.00 24.09 ? 222 PHE C CD1 1 
ATOM   5336 C CD2 . PHE C 3 240 ? 148.522 110.972 98.402  1.00 32.07 ? 222 PHE C CD2 1 
ATOM   5337 C CE1 . PHE C 3 240 ? 146.772 112.811 97.356  1.00 29.34 ? 222 PHE C CE1 1 
ATOM   5338 C CE2 . PHE C 3 240 ? 148.878 111.709 97.297  1.00 32.98 ? 222 PHE C CE2 1 
ATOM   5339 C CZ  . PHE C 3 240 ? 148.002 112.630 96.775  1.00 30.74 ? 222 PHE C CZ  1 
ATOM   5340 N N   . THR C 3 241 ? 146.044 107.179 101.420 1.00 38.69 ? 223 THR C N   1 
ATOM   5341 C CA  . THR C 3 241 ? 145.635 106.433 102.607 1.00 40.56 ? 223 THR C CA  1 
ATOM   5342 C C   . THR C 3 241 ? 146.890 106.039 103.371 1.00 46.10 ? 223 THR C C   1 
ATOM   5343 O O   . THR C 3 241 ? 147.574 105.081 102.997 1.00 47.62 ? 223 THR C O   1 
ATOM   5344 C CB  . THR C 3 241 ? 144.813 105.199 102.233 1.00 40.46 ? 223 THR C CB  1 
ATOM   5345 O OG1 . THR C 3 241 ? 143.836 105.552 101.247 1.00 43.28 ? 223 THR C OG1 1 
ATOM   5346 C CG2 . THR C 3 241 ? 144.106 104.636 103.458 1.00 37.09 ? 223 THR C CG2 1 
ATOM   5347 N N   . GLY C 3 242 ? 147.197 106.789 104.426 1.00 33.71 ? 224 GLY C N   1 
ATOM   5348 C CA  . GLY C 3 242 ? 148.291 106.460 105.317 1.00 29.83 ? 224 GLY C CA  1 
ATOM   5349 C C   . GLY C 3 242 ? 147.988 106.745 106.775 1.00 37.26 ? 224 GLY C C   1 
ATOM   5350 O O   . GLY C 3 242 ? 148.879 106.632 107.623 1.00 41.49 ? 224 GLY C O   1 
ATOM   5351 N N   . HIS C 3 243 ? 146.742 107.096 107.086 1.00 31.17 ? 225 HIS C N   1 
ATOM   5352 C CA  . HIS C 3 243 ? 146.324 107.457 108.430 1.00 29.52 ? 225 HIS C CA  1 
ATOM   5353 C C   . HIS C 3 243 ? 145.603 106.288 109.086 1.00 33.22 ? 225 HIS C C   1 
ATOM   5354 O O   . HIS C 3 243 ? 144.887 105.524 108.433 1.00 35.27 ? 225 HIS C O   1 
ATOM   5355 C CB  . HIS C 3 243 ? 145.408 108.684 108.404 1.00 31.63 ? 225 HIS C CB  1 
ATOM   5356 C CG  . HIS C 3 243 ? 146.137 109.983 108.543 1.00 32.68 ? 225 HIS C CG  1 
ATOM   5357 N ND1 . HIS C 3 243 ? 146.590 110.457 109.754 1.00 34.43 ? 225 HIS C ND1 1 
ATOM   5358 C CD2 . HIS C 3 243 ? 146.497 110.905 107.620 1.00 37.32 ? 225 HIS C CD2 1 
ATOM   5359 C CE1 . HIS C 3 243 ? 147.195 111.617 109.573 1.00 32.20 ? 225 HIS C CE1 1 
ATOM   5360 N NE2 . HIS C 3 243 ? 147.154 111.911 108.286 1.00 39.91 ? 225 HIS C NE2 1 
ATOM   5361 N N   . GLU C 3 244 ? 145.804 106.159 110.395 1.00 41.71 ? 226 GLU C N   1 
ATOM   5362 C CA  . GLU C 3 244 ? 145.174 105.116 111.192 1.00 37.00 ? 226 GLU C CA  1 
ATOM   5363 C C   . GLU C 3 244 ? 143.839 105.549 111.781 1.00 37.94 ? 226 GLU C C   1 
ATOM   5364 O O   . GLU C 3 244 ? 143.241 104.784 112.543 1.00 42.27 ? 226 GLU C O   1 
ATOM   5365 C CB  . GLU C 3 244 ? 146.115 104.684 112.330 1.00 40.59 ? 226 GLU C CB  1 
ATOM   5366 C CG  . GLU C 3 244 ? 147.398 103.903 111.952 1.00 41.12 ? 226 GLU C CG  1 
ATOM   5367 C CD  . GLU C 3 244 ? 147.282 103.009 110.725 1.00 42.10 ? 226 GLU C CD  1 
ATOM   5368 O OE1 . GLU C 3 244 ? 146.253 102.316 110.576 1.00 38.11 ? 226 GLU C OE1 1 
ATOM   5369 O OE2 . GLU C 3 244 ? 148.225 103.002 109.906 1.00 40.04 ? 226 GLU C OE2 1 
ATOM   5370 N N   . SER C 3 245 ? 143.353 106.746 111.458 1.00 35.53 ? 227 SER C N   1 
ATOM   5371 C CA  . SER C 3 245 ? 142.062 107.196 111.950 1.00 37.12 ? 227 SER C CA  1 
ATOM   5372 C C   . SER C 3 245 ? 141.638 108.433 111.169 1.00 36.75 ? 227 SER C C   1 
ATOM   5373 O O   . SER C 3 245 ? 142.315 108.867 110.234 1.00 39.90 ? 227 SER C O   1 
ATOM   5374 C CB  . SER C 3 245 ? 142.115 107.476 113.453 1.00 37.36 ? 227 SER C CB  1 
ATOM   5375 O OG  . SER C 3 245 ? 141.074 108.354 113.838 1.00 41.30 ? 227 SER C OG  1 
ATOM   5376 N N   . ASP C 3 246 ? 140.494 108.987 111.562 1.00 38.21 ? 228 ASP C N   1 
ATOM   5377 C CA  . ASP C 3 246 ? 139.908 110.128 110.868 1.00 38.30 ? 228 ASP C CA  1 
ATOM   5378 C C   . ASP C 3 246 ? 140.855 111.322 110.862 1.00 31.51 ? 228 ASP C C   1 
ATOM   5379 O O   . ASP C 3 246 ? 141.491 111.643 111.869 1.00 38.47 ? 228 ASP C O   1 
ATOM   5380 C CB  . ASP C 3 246 ? 138.588 110.537 111.526 1.00 41.14 ? 228 ASP C CB  1 
ATOM   5381 C CG  . ASP C 3 246 ? 138.701 110.694 113.026 1.00 42.39 ? 228 ASP C CG  1 
ATOM   5382 O OD1 . ASP C 3 246 ? 139.804 110.470 113.559 1.00 45.58 ? 228 ASP C OD1 1 
ATOM   5383 O OD2 . ASP C 3 246 ? 137.690 111.032 113.672 1.00 43.51 ? 228 ASP C OD2 1 
ATOM   5384 N N   . ILE C 3 247 ? 140.933 111.993 109.711 1.00 31.92 ? 229 ILE C N   1 
ATOM   5385 C CA  . ILE C 3 247 ? 141.768 113.179 109.547 1.00 38.65 ? 229 ILE C CA  1 
ATOM   5386 C C   . ILE C 3 247 ? 140.894 114.411 109.746 1.00 35.96 ? 229 ILE C C   1 
ATOM   5387 O O   . ILE C 3 247 ? 139.839 114.552 109.116 1.00 41.87 ? 229 ILE C O   1 
ATOM   5388 C CB  . ILE C 3 247 ? 142.520 113.159 108.191 1.00 26.41 ? 229 ILE C CB  1 
ATOM   5389 C CG1 . ILE C 3 247 ? 141.771 113.787 107.001 1.00 28.44 ? 229 ILE C CG1 1 
ATOM   5390 C CG2 . ILE C 3 247 ? 142.922 111.728 107.832 1.00 27.61 ? 229 ILE C CG2 1 
ATOM   5391 C CD1 . ILE C 3 247 ? 142.692 114.021 105.827 1.00 36.88 ? 229 ILE C CD1 1 
ATOM   5392 N N   . ASN C 3 248 ? 141.328 115.295 110.648 1.00 40.35 ? 230 ASN C N   1 
ATOM   5393 C CA  . ASN C 3 248 ? 140.519 116.410 111.117 1.00 37.17 ? 230 ASN C CA  1 
ATOM   5394 C C   . ASN C 3 248 ? 140.742 117.706 110.355 1.00 41.89 ? 230 ASN C C   1 
ATOM   5395 O O   . ASN C 3 248 ? 139.809 118.509 110.263 1.00 40.58 ? 230 ASN C O   1 
ATOM   5396 C CB  . ASN C 3 248 ? 140.805 116.682 112.606 1.00 33.96 ? 230 ASN C CB  1 
ATOM   5397 C CG  . ASN C 3 248 ? 139.744 116.115 113.544 1.00 39.62 ? 230 ASN C CG  1 
ATOM   5398 O OD1 . ASN C 3 248 ? 138.677 115.667 113.127 1.00 48.20 ? 230 ASN C OD1 1 
ATOM   5399 N ND2 . ASN C 3 248 ? 140.045 116.142 114.836 1.00 31.83 ? 230 ASN C ND2 1 
ATOM   5400 N N   . ALA C 3 249 ? 141.939 117.938 109.821 1.00 34.99 ? 231 ALA C N   1 
ATOM   5401 C CA  . ALA C 3 249 ? 142.242 119.196 109.154 1.00 21.66 ? 231 ALA C CA  1 
ATOM   5402 C C   . ALA C 3 249 ? 143.280 118.961 108.071 1.00 23.67 ? 231 ALA C C   1 
ATOM   5403 O O   . ALA C 3 249 ? 144.088 118.031 108.145 1.00 36.34 ? 231 ALA C O   1 
ATOM   5404 C CB  . ALA C 3 249 ? 142.741 120.245 110.146 1.00 23.85 ? 231 ALA C CB  1 
ATOM   5405 N N   . ILE C 3 250 ? 143.258 119.837 107.067 1.00 8.65  ? 232 ILE C N   1 
ATOM   5406 C CA  . ILE C 3 250 ? 144.103 119.703 105.889 1.00 16.85 ? 232 ILE C CA  1 
ATOM   5407 C C   . ILE C 3 250 ? 144.486 121.095 105.410 1.00 27.35 ? 232 ILE C C   1 
ATOM   5408 O O   . ILE C 3 250 ? 143.716 122.050 105.538 1.00 28.79 ? 232 ILE C O   1 
ATOM   5409 C CB  . ILE C 3 250 ? 143.389 118.889 104.780 1.00 18.79 ? 232 ILE C CB  1 
ATOM   5410 C CG1 . ILE C 3 250 ? 144.404 118.236 103.842 1.00 21.15 ? 232 ILE C CG1 1 
ATOM   5411 C CG2 . ILE C 3 250 ? 142.421 119.756 103.985 1.00 19.86 ? 232 ILE C CG2 1 
ATOM   5412 C CD1 . ILE C 3 250 ? 143.791 117.211 102.927 1.00 22.64 ? 232 ILE C CD1 1 
ATOM   5413 N N   . CYS C 3 251 ? 145.693 121.201 104.860 1.00 25.87 ? 233 CYS C N   1 
ATOM   5414 C CA  . CYS C 3 251 ? 146.242 122.434 104.316 1.00 7.87  ? 233 CYS C CA  1 
ATOM   5415 C C   . CYS C 3 251 ? 146.702 122.170 102.890 1.00 20.16 ? 233 CYS C C   1 
ATOM   5416 O O   . CYS C 3 251 ? 146.339 121.166 102.278 1.00 32.28 ? 233 CYS C O   1 
ATOM   5417 C CB  . CYS C 3 251 ? 147.398 122.960 105.171 1.00 12.63 ? 233 CYS C CB  1 
ATOM   5418 S SG  . CYS C 3 251 ? 147.825 124.672 104.805 1.00 39.30 ? 233 CYS C SG  1 
ATOM   5419 N N   . PHE C 3 252 ? 147.464 123.110 102.338 1.00 26.64 ? 234 PHE C N   1 
ATOM   5420 C CA  . PHE C 3 252 ? 148.068 122.936 101.024 1.00 14.89 ? 234 PHE C CA  1 
ATOM   5421 C C   . PHE C 3 252 ? 149.423 123.625 101.028 1.00 24.19 ? 234 PHE C C   1 
ATOM   5422 O O   . PHE C 3 252 ? 149.529 124.777 101.456 1.00 32.40 ? 234 PHE C O   1 
ATOM   5423 C CB  . PHE C 3 252 ? 147.178 123.515 99.920  1.00 15.50 ? 234 PHE C CB  1 
ATOM   5424 C CG  . PHE C 3 252 ? 147.092 122.650 98.696  1.00 26.38 ? 234 PHE C CG  1 
ATOM   5425 C CD1 . PHE C 3 252 ? 148.097 122.664 97.748  1.00 34.53 ? 234 PHE C CD1 1 
ATOM   5426 C CD2 . PHE C 3 252 ? 146.010 121.815 98.500  1.00 23.33 ? 234 PHE C CD2 1 
ATOM   5427 C CE1 . PHE C 3 252 ? 148.018 121.866 96.626  1.00 26.94 ? 234 PHE C CE1 1 
ATOM   5428 C CE2 . PHE C 3 252 ? 145.929 121.019 97.381  1.00 14.79 ? 234 PHE C CE2 1 
ATOM   5429 C CZ  . PHE C 3 252 ? 146.933 121.043 96.445  1.00 11.11 ? 234 PHE C CZ  1 
ATOM   5430 N N   . PHE C 3 253 ? 150.448 122.919 100.564 1.00 23.05 ? 235 PHE C N   1 
ATOM   5431 C CA  . PHE C 3 253 ? 151.775 123.501 100.494 1.00 25.99 ? 235 PHE C CA  1 
ATOM   5432 C C   . PHE C 3 253 ? 151.757 124.681 99.515  1.00 35.94 ? 235 PHE C C   1 
ATOM   5433 O O   . PHE C 3 253 ? 151.136 124.589 98.453  1.00 41.52 ? 235 PHE C O   1 
ATOM   5434 C CB  . PHE C 3 253 ? 152.783 122.450 100.038 1.00 27.42 ? 235 PHE C CB  1 
ATOM   5435 C CG  . PHE C 3 253 ? 154.203 122.754 100.421 1.00 29.65 ? 235 PHE C CG  1 
ATOM   5436 C CD1 . PHE C 3 253 ? 154.680 122.423 101.671 1.00 35.47 ? 235 PHE C CD1 1 
ATOM   5437 C CD2 . PHE C 3 253 ? 155.066 123.346 99.524  1.00 26.39 ? 235 PHE C CD2 1 
ATOM   5438 C CE1 . PHE C 3 253 ? 155.984 122.691 102.023 1.00 31.55 ? 235 PHE C CE1 1 
ATOM   5439 C CE2 . PHE C 3 253 ? 156.370 123.618 99.870  1.00 25.48 ? 235 PHE C CE2 1 
ATOM   5440 C CZ  . PHE C 3 253 ? 156.829 123.289 101.120 1.00 24.22 ? 235 PHE C CZ  1 
ATOM   5441 N N   . PRO C 3 254 ? 152.403 125.812 99.849  1.00 34.23 ? 236 PRO C N   1 
ATOM   5442 C CA  . PRO C 3 254 ? 152.326 126.972 98.938  1.00 30.70 ? 236 PRO C CA  1 
ATOM   5443 C C   . PRO C 3 254 ? 152.865 126.702 97.545  1.00 29.25 ? 236 PRO C C   1 
ATOM   5444 O O   . PRO C 3 254 ? 152.429 127.350 96.586  1.00 27.83 ? 236 PRO C O   1 
ATOM   5445 C CB  . PRO C 3 254 ? 153.154 128.041 99.662  1.00 28.17 ? 236 PRO C CB  1 
ATOM   5446 C CG  . PRO C 3 254 ? 153.127 127.650 101.072 1.00 20.29 ? 236 PRO C CG  1 
ATOM   5447 C CD  . PRO C 3 254 ? 153.159 126.162 101.067 1.00 29.88 ? 236 PRO C CD  1 
ATOM   5448 N N   . ASN C 3 255 ? 153.805 125.766 97.404  1.00 30.74 ? 237 ASN C N   1 
ATOM   5449 C CA  . ASN C 3 255 ? 154.261 125.357 96.079  1.00 32.65 ? 237 ASN C CA  1 
ATOM   5450 C C   . ASN C 3 255 ? 153.113 124.795 95.250  1.00 33.05 ? 237 ASN C C   1 
ATOM   5451 O O   . ASN C 3 255 ? 153.127 124.888 94.017  1.00 37.44 ? 237 ASN C O   1 
ATOM   5452 C CB  . ASN C 3 255 ? 155.380 124.324 96.213  1.00 35.25 ? 237 ASN C CB  1 
ATOM   5453 C CG  . ASN C 3 255 ? 156.033 123.990 94.890  1.00 37.90 ? 237 ASN C CG  1 
ATOM   5454 O OD1 . ASN C 3 255 ? 155.989 122.847 94.437  1.00 39.40 ? 237 ASN C OD1 1 
ATOM   5455 N ND2 . ASN C 3 255 ? 156.649 124.984 94.264  1.00 35.63 ? 237 ASN C ND2 1 
ATOM   5456 N N   . GLY C 3 256 ? 152.114 124.210 95.905  1.00 27.25 ? 238 GLY C N   1 
ATOM   5457 C CA  . GLY C 3 256 ? 150.972 123.636 95.228  1.00 24.39 ? 238 GLY C CA  1 
ATOM   5458 C C   . GLY C 3 256 ? 151.127 122.193 94.806  1.00 31.08 ? 238 GLY C C   1 
ATOM   5459 O O   . GLY C 3 256 ? 150.243 121.677 94.113  1.00 42.11 ? 238 GLY C O   1 
ATOM   5460 N N   . ASN C 3 257 ? 152.218 121.524 95.202  1.00 30.08 ? 239 ASN C N   1 
ATOM   5461 C CA  . ASN C 3 257 ? 152.470 120.132 94.846  1.00 35.35 ? 239 ASN C CA  1 
ATOM   5462 C C   . ASN C 3 257 ? 152.588 119.248 96.084  1.00 32.73 ? 239 ASN C C   1 
ATOM   5463 O O   . ASN C 3 257 ? 153.188 118.171 96.016  1.00 40.11 ? 239 ASN C O   1 
ATOM   5464 C CB  . ASN C 3 257 ? 153.746 120.021 93.999  1.00 38.31 ? 239 ASN C CB  1 
ATOM   5465 C CG  . ASN C 3 257 ? 153.619 120.654 92.604  1.00 42.19 ? 239 ASN C CG  1 
ATOM   5466 O OD1 . ASN C 3 257 ? 154.627 121.087 92.045  1.00 41.16 ? 239 ASN C OD1 1 
ATOM   5467 N ND2 . ASN C 3 257 ? 152.416 120.680 92.024  1.00 39.22 ? 239 ASN C ND2 1 
ATOM   5468 N N   . ALA C 3 258 ? 152.028 119.673 97.213  1.00 27.96 ? 240 ALA C N   1 
ATOM   5469 C CA  . ALA C 3 258 ? 152.045 118.867 98.423  1.00 25.69 ? 240 ALA C CA  1 
ATOM   5470 C C   . ALA C 3 258 ? 151.032 119.448 99.393  1.00 27.46 ? 240 ALA C C   1 
ATOM   5471 O O   . ALA C 3 258 ? 150.554 120.570 99.217  1.00 36.83 ? 240 ALA C O   1 
ATOM   5472 C CB  . ALA C 3 258 ? 153.439 118.823 99.054  1.00 25.59 ? 240 ALA C CB  1 
ATOM   5473 N N   . PHE C 3 259 ? 150.706 118.668 100.418 1.00 23.52 ? 241 PHE C N   1 
ATOM   5474 C CA  . PHE C 3 259 ? 149.799 119.130 101.456 1.00 28.85 ? 241 PHE C CA  1 
ATOM   5475 C C   . PHE C 3 259 ? 150.039 118.330 102.726 1.00 29.40 ? 241 PHE C C   1 
ATOM   5476 O O   . PHE C 3 259 ? 150.697 117.287 102.715 1.00 38.86 ? 241 PHE C O   1 
ATOM   5477 C CB  . PHE C 3 259 ? 148.338 119.029 101.014 1.00 25.93 ? 241 PHE C CB  1 
ATOM   5478 C CG  . PHE C 3 259 ? 147.890 117.640 100.688 1.00 28.35 ? 241 PHE C CG  1 
ATOM   5479 C CD1 . PHE C 3 259 ? 148.061 117.122 99.420  1.00 29.51 ? 241 PHE C CD1 1 
ATOM   5480 C CD2 . PHE C 3 259 ? 147.274 116.859 101.647 1.00 27.70 ? 241 PHE C CD2 1 
ATOM   5481 C CE1 . PHE C 3 259 ? 147.640 115.849 99.123  1.00 29.59 ? 241 PHE C CE1 1 
ATOM   5482 C CE2 . PHE C 3 259 ? 146.856 115.587 101.353 1.00 23.80 ? 241 PHE C CE2 1 
ATOM   5483 C CZ  . PHE C 3 259 ? 147.036 115.084 100.094 1.00 22.69 ? 241 PHE C CZ  1 
ATOM   5484 N N   . ALA C 3 260 ? 149.492 118.840 103.829 1.00 14.54 ? 242 ALA C N   1 
ATOM   5485 C CA  . ALA C 3 260 ? 149.662 118.255 105.150 1.00 11.40 ? 242 ALA C CA  1 
ATOM   5486 C C   . ALA C 3 260 ? 148.304 117.963 105.764 1.00 21.08 ? 242 ALA C C   1 
ATOM   5487 O O   . ALA C 3 260 ? 147.400 118.801 105.715 1.00 36.71 ? 242 ALA C O   1 
ATOM   5488 C CB  . ALA C 3 260 ? 150.454 119.183 106.068 1.00 28.68 ? 242 ALA C CB  1 
ATOM   5489 N N   . THR C 3 261 ? 148.175 116.776 106.352 1.00 22.41 ? 243 THR C N   1 
ATOM   5490 C CA  . THR C 3 261 ? 146.945 116.314 106.978 1.00 21.36 ? 243 THR C CA  1 
ATOM   5491 C C   . THR C 3 261 ? 147.154 116.183 108.480 1.00 27.40 ? 243 THR C C   1 
ATOM   5492 O O   . THR C 3 261 ? 148.289 116.079 108.955 1.00 41.57 ? 243 THR C O   1 
ATOM   5493 C CB  . THR C 3 261 ? 146.507 114.963 106.407 1.00 28.00 ? 243 THR C CB  1 
ATOM   5494 O OG1 . THR C 3 261 ? 147.617 114.060 106.417 1.00 36.37 ? 243 THR C OG1 1 
ATOM   5495 C CG2 . THR C 3 261 ? 146.006 115.117 104.982 1.00 28.77 ? 243 THR C CG2 1 
ATOM   5496 N N   . GLY C 3 262 ? 146.049 116.193 109.222 1.00 20.42 ? 244 GLY C N   1 
ATOM   5497 C CA  . GLY C 3 262 ? 146.091 116.036 110.664 1.00 34.32 ? 244 GLY C CA  1 
ATOM   5498 C C   . GLY C 3 262 ? 144.950 115.191 111.189 1.00 30.95 ? 244 GLY C C   1 
ATOM   5499 O O   . GLY C 3 262 ? 143.784 115.504 110.939 1.00 28.42 ? 244 GLY C O   1 
ATOM   5500 N N   . SER C 3 263 ? 145.274 114.127 111.922 1.00 27.62 ? 245 SER C N   1 
ATOM   5501 C CA  . SER C 3 263 ? 144.309 113.169 112.439 1.00 25.07 ? 245 SER C CA  1 
ATOM   5502 C C   . SER C 3 263 ? 144.341 113.152 113.961 1.00 32.27 ? 245 SER C C   1 
ATOM   5503 O O   . SER C 3 263 ? 145.155 113.830 114.595 1.00 52.30 ? 245 SER C O   1 
ATOM   5504 C CB  . SER C 3 263 ? 144.597 111.784 111.859 1.00 39.00 ? 245 SER C CB  1 
ATOM   5505 O OG  . SER C 3 263 ? 145.836 111.290 112.336 1.00 42.15 ? 245 SER C OG  1 
ATOM   5506 N N   . ASP C 3 264 ? 143.446 112.358 114.556 1.00 29.50 ? 246 ASP C N   1 
ATOM   5507 C CA  . ASP C 3 264 ? 143.375 112.232 116.006 1.00 37.56 ? 246 ASP C CA  1 
ATOM   5508 C C   . ASP C 3 264 ? 144.348 111.191 116.556 1.00 45.53 ? 246 ASP C C   1 
ATOM   5509 O O   . ASP C 3 264 ? 144.237 110.807 117.728 1.00 53.51 ? 246 ASP C O   1 
ATOM   5510 C CB  . ASP C 3 264 ? 141.946 111.911 116.449 1.00 35.71 ? 246 ASP C CB  1 
ATOM   5511 C CG  . ASP C 3 264 ? 141.463 110.562 115.961 1.00 41.14 ? 246 ASP C CG  1 
ATOM   5512 O OD1 . ASP C 3 264 ? 142.156 109.923 115.144 1.00 46.91 ? 246 ASP C OD1 1 
ATOM   5513 O OD2 . ASP C 3 264 ? 140.376 110.134 116.401 1.00 41.90 ? 246 ASP C OD2 1 
ATOM   5514 N N   . ASP C 3 265 ? 145.293 110.720 115.743 1.00 39.52 ? 247 ASP C N   1 
ATOM   5515 C CA  . ASP C 3 265 ? 146.350 109.824 116.189 1.00 43.02 ? 247 ASP C CA  1 
ATOM   5516 C C   . ASP C 3 265 ? 147.581 110.587 116.675 1.00 44.82 ? 247 ASP C C   1 
ATOM   5517 O O   . ASP C 3 265 ? 148.605 109.967 116.976 1.00 43.92 ? 247 ASP C O   1 
ATOM   5518 C CB  . ASP C 3 265 ? 146.725 108.864 115.052 1.00 38.46 ? 247 ASP C CB  1 
ATOM   5519 C CG  . ASP C 3 265 ? 147.579 107.689 115.520 1.00 47.19 ? 247 ASP C CG  1 
ATOM   5520 O OD1 . ASP C 3 265 ? 147.445 107.270 116.689 1.00 46.46 ? 247 ASP C OD1 1 
ATOM   5521 O OD2 . ASP C 3 265 ? 148.386 107.184 114.712 1.00 45.98 ? 247 ASP C OD2 1 
ATOM   5522 N N   . ALA C 3 266 ? 147.499 111.918 116.771 1.00 37.05 ? 248 ALA C N   1 
ATOM   5523 C CA  . ALA C 3 266 ? 148.628 112.753 117.175 1.00 40.62 ? 248 ALA C CA  1 
ATOM   5524 C C   . ALA C 3 266 ? 149.773 112.672 116.172 1.00 43.35 ? 248 ALA C C   1 
ATOM   5525 O O   . ALA C 3 266 ? 150.945 112.746 116.550 1.00 49.92 ? 248 ALA C O   1 
ATOM   5526 C CB  . ALA C 3 266 ? 149.128 112.378 118.573 1.00 48.96 ? 248 ALA C CB  1 
ATOM   5527 N N   . THR C 3 267 ? 149.445 112.515 114.889 1.00 34.37 ? 249 THR C N   1 
ATOM   5528 C CA  . THR C 3 267 ? 150.438 112.403 113.828 1.00 32.36 ? 249 THR C CA  1 
ATOM   5529 C C   . THR C 3 267 ? 149.982 113.216 112.629 1.00 33.80 ? 249 THR C C   1 
ATOM   5530 O O   . THR C 3 267 ? 148.947 112.910 112.028 1.00 42.41 ? 249 THR C O   1 
ATOM   5531 C CB  . THR C 3 267 ? 150.654 110.943 113.417 1.00 32.44 ? 249 THR C CB  1 
ATOM   5532 O OG1 . THR C 3 267 ? 149.420 110.387 112.947 1.00 40.73 ? 249 THR C OG1 1 
ATOM   5533 C CG2 . THR C 3 267 ? 151.162 110.123 114.592 1.00 33.83 ? 249 THR C CG2 1 
ATOM   5534 N N   . CYS C 3 268 ? 150.748 114.248 112.287 1.00 30.18 ? 250 CYS C N   1 
ATOM   5535 C CA  . CYS C 3 268 ? 150.606 114.928 111.010 1.00 30.00 ? 250 CYS C CA  1 
ATOM   5536 C C   . CYS C 3 268 ? 151.432 114.199 109.962 1.00 35.26 ? 250 CYS C C   1 
ATOM   5537 O O   . CYS C 3 268 ? 152.458 113.589 110.271 1.00 42.67 ? 250 CYS C O   1 
ATOM   5538 C CB  . CYS C 3 268 ? 151.061 116.384 111.102 1.00 24.40 ? 250 CYS C CB  1 
ATOM   5539 S SG  . CYS C 3 268 ? 149.896 117.489 111.912 1.00 29.73 ? 250 CYS C SG  1 
ATOM   5540 N N   . ARG C 3 269 ? 150.969 114.262 108.716 1.00 27.54 ? 251 ARG C N   1 
ATOM   5541 C CA  . ARG C 3 269 ? 151.630 113.603 107.600 1.00 27.23 ? 251 ARG C CA  1 
ATOM   5542 C C   . ARG C 3 269 ? 151.719 114.574 106.437 1.00 25.52 ? 251 ARG C C   1 
ATOM   5543 O O   . ARG C 3 269 ? 150.826 115.403 106.249 1.00 24.10 ? 251 ARG C O   1 
ATOM   5544 C CB  . ARG C 3 269 ? 150.877 112.340 107.174 1.00 29.01 ? 251 ARG C CB  1 
ATOM   5545 C CG  . ARG C 3 269 ? 151.211 111.113 107.997 1.00 28.28 ? 251 ARG C CG  1 
ATOM   5546 C CD  . ARG C 3 269 ? 150.366 109.925 107.580 1.00 29.89 ? 251 ARG C CD  1 
ATOM   5547 N NE  . ARG C 3 269 ? 150.773 108.694 108.249 1.00 30.40 ? 251 ARG C NE  1 
ATOM   5548 C CZ  . ARG C 3 269 ? 150.452 108.358 109.493 1.00 34.52 ? 251 ARG C CZ  1 
ATOM   5549 N NH1 . ARG C 3 269 ? 149.718 109.146 110.262 1.00 35.53 ? 251 ARG C NH1 1 
ATOM   5550 N NH2 . ARG C 3 269 ? 150.877 107.194 109.977 1.00 32.35 ? 251 ARG C NH2 1 
ATOM   5551 N N   . LEU C 3 270 ? 152.796 114.466 105.664 1.00 32.50 ? 252 LEU C N   1 
ATOM   5552 C CA  . LEU C 3 270 ? 153.020 115.289 104.483 1.00 36.49 ? 252 LEU C CA  1 
ATOM   5553 C C   . LEU C 3 270 ? 152.886 114.408 103.249 1.00 41.40 ? 252 LEU C C   1 
ATOM   5554 O O   . LEU C 3 270 ? 153.612 113.417 103.110 1.00 38.78 ? 252 LEU C O   1 
ATOM   5555 C CB  . LEU C 3 270 ? 154.404 115.945 104.533 1.00 29.15 ? 252 LEU C CB  1 
ATOM   5556 C CG  . LEU C 3 270 ? 154.901 116.733 103.316 1.00 26.65 ? 252 LEU C CG  1 
ATOM   5557 C CD1 . LEU C 3 270 ? 154.067 117.979 103.119 1.00 22.81 ? 252 LEU C CD1 1 
ATOM   5558 C CD2 . LEU C 3 270 ? 156.363 117.095 103.474 1.00 32.49 ? 252 LEU C CD2 1 
ATOM   5559 N N   . PHE C 3 271 ? 151.967 114.775 102.358 1.00 27.90 ? 253 PHE C N   1 
ATOM   5560 C CA  . PHE C 3 271 ? 151.709 114.044 101.127 1.00 13.53 ? 253 PHE C CA  1 
ATOM   5561 C C   . PHE C 3 271 ? 152.103 114.898 99.933  1.00 20.27 ? 253 PHE C C   1 
ATOM   5562 O O   . PHE C 3 271 ? 152.059 116.129 99.990  1.00 31.14 ? 253 PHE C O   1 
ATOM   5563 C CB  . PHE C 3 271 ? 150.236 113.655 100.999 1.00 21.87 ? 253 PHE C CB  1 
ATOM   5564 C CG  . PHE C 3 271 ? 149.767 112.690 102.044 1.00 25.32 ? 253 PHE C CG  1 
ATOM   5565 C CD1 . PHE C 3 271 ? 150.085 111.348 101.954 1.00 31.30 ? 253 PHE C CD1 1 
ATOM   5566 C CD2 . PHE C 3 271 ? 148.985 113.116 103.099 1.00 21.06 ? 253 PHE C CD2 1 
ATOM   5567 C CE1 . PHE C 3 271 ? 149.650 110.458 102.906 1.00 30.11 ? 253 PHE C CE1 1 
ATOM   5568 C CE2 . PHE C 3 271 ? 148.547 112.227 104.051 1.00 23.75 ? 253 PHE C CE2 1 
ATOM   5569 C CZ  . PHE C 3 271 ? 148.879 110.897 103.954 1.00 31.95 ? 253 PHE C CZ  1 
ATOM   5570 N N   . ASP C 3 272 ? 152.490 114.228 98.851  1.00 29.13 ? 254 ASP C N   1 
ATOM   5571 C CA  . ASP C 3 272 ? 152.859 114.877 97.601  1.00 36.68 ? 254 ASP C CA  1 
ATOM   5572 C C   . ASP C 3 272 ? 151.874 114.480 96.512  1.00 36.17 ? 254 ASP C C   1 
ATOM   5573 O O   . ASP C 3 272 ? 151.369 113.354 96.496  1.00 29.07 ? 254 ASP C O   1 
ATOM   5574 C CB  . ASP C 3 272 ? 154.281 114.501 97.185  1.00 38.90 ? 254 ASP C CB  1 
ATOM   5575 C CG  . ASP C 3 272 ? 154.841 115.423 96.117  1.00 44.58 ? 254 ASP C CG  1 
ATOM   5576 O OD1 . ASP C 3 272 ? 154.160 115.651 95.095  1.00 41.62 ? 254 ASP C OD1 1 
ATOM   5577 O OD2 . ASP C 3 272 ? 155.962 115.936 96.309  1.00 49.20 ? 254 ASP C OD2 1 
ATOM   5578 N N   . LEU C 3 273 ? 151.609 115.417 95.601  1.00 32.47 ? 255 LEU C N   1 
ATOM   5579 C CA  . LEU C 3 273 ? 150.654 115.162 94.529  1.00 28.17 ? 255 LEU C CA  1 
ATOM   5580 C C   . LEU C 3 273 ? 151.303 114.400 93.382  1.00 36.36 ? 255 LEU C C   1 
ATOM   5581 O O   . LEU C 3 273 ? 150.718 113.453 92.843  1.00 47.00 ? 255 LEU C O   1 
ATOM   5582 C CB  . LEU C 3 273 ? 150.065 116.480 94.032  1.00 33.71 ? 255 LEU C CB  1 
ATOM   5583 C CG  . LEU C 3 273 ? 148.857 117.001 94.808  1.00 35.34 ? 255 LEU C CG  1 
ATOM   5584 C CD1 . LEU C 3 273 ? 149.248 117.447 96.200  1.00 31.56 ? 255 LEU C CD1 1 
ATOM   5585 C CD2 . LEU C 3 273 ? 148.212 118.141 94.044  1.00 37.26 ? 255 LEU C CD2 1 
ATOM   5586 N N   . ARG C 3 274 ? 152.512 114.802 92.985  1.00 40.76 ? 256 ARG C N   1 
ATOM   5587 C CA  . ARG C 3 274 ? 153.161 114.154 91.852  1.00 48.04 ? 256 ARG C CA  1 
ATOM   5588 C C   . ARG C 3 274 ? 153.669 112.765 92.224  1.00 50.02 ? 256 ARG C C   1 
ATOM   5589 O O   . ARG C 3 274 ? 153.483 111.805 91.467  1.00 46.03 ? 256 ARG C O   1 
ATOM   5590 C CB  . ARG C 3 274 ? 154.302 115.027 91.334  1.00 51.08 ? 256 ARG C CB  1 
ATOM   5591 C CG  . ARG C 3 274 ? 153.883 116.451 90.975  1.00 52.91 ? 256 ARG C CG  1 
ATOM   5592 C CD  . ARG C 3 274 ? 155.046 117.256 90.415  1.00 48.30 ? 256 ARG C CD  1 
ATOM   5593 N NE  . ARG C 3 274 ? 155.681 118.089 91.430  1.00 47.64 ? 256 ARG C NE  1 
ATOM   5594 C CZ  . ARG C 3 274 ? 156.731 118.872 91.217  1.00 54.12 ? 256 ARG C CZ  1 
ATOM   5595 N NH1 . ARG C 3 274 ? 157.312 118.952 90.028  1.00 51.60 ? 256 ARG C NH1 1 
ATOM   5596 N NH2 . ARG C 3 274 ? 157.217 119.592 92.224  1.00 52.03 ? 256 ARG C NH2 1 
ATOM   5597 N N   . ALA C 3 275 ? 154.310 112.634 93.389  1.00 53.92 ? 257 ALA C N   1 
ATOM   5598 C CA  . ALA C 3 275 ? 154.820 111.335 93.813  1.00 52.59 ? 257 ALA C CA  1 
ATOM   5599 C C   . ALA C 3 275 ? 153.710 110.383 94.238  1.00 52.35 ? 257 ALA C C   1 
ATOM   5600 O O   . ALA C 3 275 ? 153.924 109.167 94.230  1.00 57.16 ? 257 ALA C O   1 
ATOM   5601 C CB  . ALA C 3 275 ? 155.817 111.503 94.960  1.00 52.49 ? 257 ALA C CB  1 
ATOM   5602 N N   . ASP C 3 276 ? 152.544 110.902 94.623  1.00 48.90 ? 258 ASP C N   1 
ATOM   5603 C CA  . ASP C 3 276 ? 151.358 110.120 94.957  1.00 47.00 ? 258 ASP C CA  1 
ATOM   5604 C C   . ASP C 3 276 ? 151.528 109.300 96.232  1.00 50.84 ? 258 ASP C C   1 
ATOM   5605 O O   . ASP C 3 276 ? 150.771 108.345 96.451  1.00 53.21 ? 258 ASP C O   1 
ATOM   5606 C CB  . ASP C 3 276 ? 150.965 109.195 93.796  1.00 44.56 ? 258 ASP C CB  1 
ATOM   5607 C CG  . ASP C 3 276 ? 149.528 108.713 93.886  1.00 49.18 ? 258 ASP C CG  1 
ATOM   5608 O OD1 . ASP C 3 276 ? 148.608 109.525 93.659  1.00 54.49 ? 258 ASP C OD1 1 
ATOM   5609 O OD2 . ASP C 3 276 ? 149.321 107.519 94.188  1.00 50.77 ? 258 ASP C OD2 1 
ATOM   5610 N N   . GLN C 3 277 ? 152.492 109.639 97.088  1.00 43.14 ? 259 GLN C N   1 
ATOM   5611 C CA  . GLN C 3 277 ? 152.758 108.863 98.291  1.00 42.13 ? 259 GLN C CA  1 
ATOM   5612 C C   . GLN C 3 277 ? 153.209 109.782 99.418  1.00 39.86 ? 259 GLN C C   1 
ATOM   5613 O O   . GLN C 3 277 ? 153.691 110.894 99.196  1.00 49.42 ? 259 GLN C O   1 
ATOM   5614 C CB  . GLN C 3 277 ? 153.788 107.755 98.010  1.00 45.84 ? 259 GLN C CB  1 
ATOM   5615 C CG  . GLN C 3 277 ? 155.207 108.214 97.671  1.00 44.36 ? 259 GLN C CG  1 
ATOM   5616 C CD  . GLN C 3 277 ? 156.260 107.390 98.378  1.00 46.30 ? 259 GLN C CD  1 
ATOM   5617 O OE1 . GLN C 3 277 ? 156.748 106.398 97.841  1.00 52.05 ? 259 GLN C OE1 1 
ATOM   5618 N NE2 . GLN C 3 277 ? 156.617 107.796 99.590  1.00 44.24 ? 259 GLN C NE2 1 
ATOM   5619 N N   . GLU C 3 278 ? 153.035 109.292 100.642 1.00 34.37 ? 260 GLU C N   1 
ATOM   5620 C CA  . GLU C 3 278 ? 153.453 110.016 101.832 1.00 35.88 ? 260 GLU C CA  1 
ATOM   5621 C C   . GLU C 3 278 ? 154.962 110.234 101.831 1.00 35.10 ? 260 GLU C C   1 
ATOM   5622 O O   . GLU C 3 278 ? 155.735 109.376 101.398 1.00 40.73 ? 260 GLU C O   1 
ATOM   5623 C CB  . GLU C 3 278 ? 153.039 109.240 103.082 1.00 35.60 ? 260 GLU C CB  1 
ATOM   5624 C CG  . GLU C 3 278 ? 153.182 109.994 104.389 1.00 38.96 ? 260 GLU C CG  1 
ATOM   5625 C CD  . GLU C 3 278 ? 152.958 109.098 105.588 1.00 42.39 ? 260 GLU C CD  1 
ATOM   5626 O OE1 . GLU C 3 278 ? 152.120 108.179 105.494 1.00 36.90 ? 260 GLU C OE1 1 
ATOM   5627 O OE2 . GLU C 3 278 ? 153.629 109.299 106.618 1.00 42.09 ? 260 GLU C OE2 1 
ATOM   5628 N N   . LEU C 3 279 ? 155.375 111.398 102.331 1.00 32.61 ? 261 LEU C N   1 
ATOM   5629 C CA  . LEU C 3 279 ? 156.779 111.782 102.406 1.00 38.56 ? 261 LEU C CA  1 
ATOM   5630 C C   . LEU C 3 279 ? 157.321 111.764 103.827 1.00 40.57 ? 261 LEU C C   1 
ATOM   5631 O O   . LEU C 3 279 ? 158.361 111.149 104.081 1.00 38.98 ? 261 LEU C O   1 
ATOM   5632 C CB  . LEU C 3 279 ? 156.970 113.178 101.800 1.00 37.64 ? 261 LEU C CB  1 
ATOM   5633 C CG  . LEU C 3 279 ? 157.395 113.193 100.330 1.00 36.93 ? 261 LEU C CG  1 
ATOM   5634 C CD1 . LEU C 3 279 ? 157.104 114.544 99.701  1.00 37.62 ? 261 LEU C CD1 1 
ATOM   5635 C CD2 . LEU C 3 279 ? 158.867 112.844 100.183 1.00 43.34 ? 261 LEU C CD2 1 
ATOM   5636 N N   . MET C 3 280 ? 156.642 112.428 104.761 1.00 37.25 ? 262 MET C N   1 
ATOM   5637 C CA  . MET C 3 280 ? 157.084 112.481 106.149 1.00 36.64 ? 262 MET C CA  1 
ATOM   5638 C C   . MET C 3 280 ? 155.876 112.482 107.069 1.00 37.29 ? 262 MET C C   1 
ATOM   5639 O O   . MET C 3 280 ? 154.789 112.937 106.703 1.00 42.07 ? 262 MET C O   1 
ATOM   5640 C CB  . MET C 3 280 ? 157.945 113.720 106.427 1.00 31.15 ? 262 MET C CB  1 
ATOM   5641 C CG  . MET C 3 280 ? 159.029 113.512 107.483 1.00 39.04 ? 262 MET C CG  1 
ATOM   5642 S SD  . MET C 3 280 ? 160.509 114.494 107.217 1.00 64.09 ? 262 MET C SD  1 
ATOM   5643 C CE  . MET C 3 280 ? 161.690 113.199 106.861 1.00 42.95 ? 262 MET C CE  1 
ATOM   5644 N N   . THR C 3 281 ? 156.093 111.961 108.276 1.00 31.58 ? 263 THR C N   1 
ATOM   5645 C CA  . THR C 3 281 ? 155.106 111.959 109.343 1.00 32.66 ? 263 THR C CA  1 
ATOM   5646 C C   . THR C 3 281 ? 155.712 112.604 110.580 1.00 25.61 ? 263 THR C C   1 
ATOM   5647 O O   . THR C 3 281 ? 156.865 112.343 110.931 1.00 27.60 ? 263 THR C O   1 
ATOM   5648 C CB  . THR C 3 281 ? 154.619 110.536 109.675 1.00 33.68 ? 263 THR C CB  1 
ATOM   5649 O OG1 . THR C 3 281 ? 153.621 110.595 110.700 1.00 32.00 ? 263 THR C OG1 1 
ATOM   5650 C CG2 . THR C 3 281 ? 155.769 109.639 110.136 1.00 39.05 ? 263 THR C CG2 1 
ATOM   5651 N N   . TYR C 3 282 ? 154.921 113.448 111.238 1.00 19.70 ? 264 TYR C N   1 
ATOM   5652 C CA  . TYR C 3 282 ? 155.357 114.208 112.403 1.00 27.23 ? 264 TYR C CA  1 
ATOM   5653 C C   . TYR C 3 282 ? 154.701 113.628 113.646 1.00 31.17 ? 264 TYR C C   1 
ATOM   5654 O O   . TYR C 3 282 ? 153.503 113.828 113.865 1.00 34.01 ? 264 TYR C O   1 
ATOM   5655 C CB  . TYR C 3 282 ? 155.007 115.688 112.250 1.00 34.54 ? 264 TYR C CB  1 
ATOM   5656 C CG  . TYR C 3 282 ? 155.405 116.269 110.915 1.00 34.51 ? 264 TYR C CG  1 
ATOM   5657 C CD1 . TYR C 3 282 ? 156.731 116.526 110.629 1.00 34.31 ? 264 TYR C CD1 1 
ATOM   5658 C CD2 . TYR C 3 282 ? 154.458 116.578 109.953 1.00 31.48 ? 264 TYR C CD2 1 
ATOM   5659 C CE1 . TYR C 3 282 ? 157.113 117.056 109.420 1.00 32.48 ? 264 TYR C CE1 1 
ATOM   5660 C CE2 . TYR C 3 282 ? 154.829 117.113 108.737 1.00 28.03 ? 264 TYR C CE2 1 
ATOM   5661 C CZ  . TYR C 3 282 ? 156.160 117.350 108.478 1.00 30.53 ? 264 TYR C CZ  1 
ATOM   5662 O OH  . TYR C 3 282 ? 156.545 117.884 107.272 1.00 34.45 ? 264 TYR C OH  1 
ATOM   5663 N N   . SER C 3 283 ? 155.491 112.936 114.465 1.00 42.40 ? 265 SER C N   1 
ATOM   5664 C CA  . SER C 3 283 ? 154.973 112.246 115.637 1.00 42.97 ? 265 SER C CA  1 
ATOM   5665 C C   . SER C 3 283 ? 155.984 112.349 116.768 1.00 45.02 ? 265 SER C C   1 
ATOM   5666 O O   . SER C 3 283 ? 157.185 112.509 116.541 1.00 49.06 ? 265 SER C O   1 
ATOM   5667 C CB  . SER C 3 283 ? 154.671 110.777 115.327 1.00 46.04 ? 265 SER C CB  1 
ATOM   5668 O OG  . SER C 3 283 ? 155.869 110.039 115.166 1.00 43.46 ? 265 SER C OG  1 
ATOM   5669 N N   . HIS C 3 284 ? 155.474 112.252 117.994 1.00 55.39 ? 266 HIS C N   1 
ATOM   5670 C CA  . HIS C 3 284 ? 156.308 112.252 119.186 1.00 56.33 ? 266 HIS C CA  1 
ATOM   5671 C C   . HIS C 3 284 ? 155.575 111.487 120.279 1.00 61.28 ? 266 HIS C C   1 
ATOM   5672 O O   . HIS C 3 284 ? 154.343 111.460 120.328 1.00 63.21 ? 266 HIS C O   1 
ATOM   5673 C CB  . HIS C 3 284 ? 156.643 113.679 119.633 1.00 58.14 ? 266 HIS C CB  1 
ATOM   5674 C CG  . HIS C 3 284 ? 157.851 113.771 120.513 1.00 64.57 ? 266 HIS C CG  1 
ATOM   5675 N ND1 . HIS C 3 284 ? 157.771 113.783 121.889 1.00 64.91 ? 266 HIS C ND1 1 
ATOM   5676 C CD2 . HIS C 3 284 ? 159.168 113.861 120.213 1.00 61.58 ? 266 HIS C CD2 1 
ATOM   5677 C CE1 . HIS C 3 284 ? 158.987 113.873 122.398 1.00 62.34 ? 266 HIS C CE1 1 
ATOM   5678 N NE2 . HIS C 3 284 ? 159.853 113.922 121.403 1.00 62.36 ? 266 HIS C NE2 1 
ATOM   5679 N N   . ASP C 3 285 ? 156.349 110.865 121.167 1.00 73.33 ? 267 ASP C N   1 
ATOM   5680 C CA  . ASP C 3 285 ? 155.782 109.993 122.190 1.00 74.65 ? 267 ASP C CA  1 
ATOM   5681 C C   . ASP C 3 285 ? 155.096 110.758 123.312 1.00 70.40 ? 267 ASP C C   1 
ATOM   5682 O O   . ASP C 3 285 ? 154.150 110.237 123.914 1.00 70.30 ? 267 ASP C O   1 
ATOM   5683 C CB  . ASP C 3 285 ? 156.875 109.100 122.784 1.00 75.99 ? 267 ASP C CB  1 
ATOM   5684 C CG  . ASP C 3 285 ? 157.444 108.121 121.773 1.00 75.81 ? 267 ASP C CG  1 
ATOM   5685 O OD1 . ASP C 3 285 ? 156.705 107.712 120.853 1.00 71.25 ? 267 ASP C OD1 1 
ATOM   5686 O OD2 . ASP C 3 285 ? 158.633 107.761 121.899 1.00 73.77 ? 267 ASP C OD2 1 
ATOM   5687 N N   . ASN C 3 286 ? 155.546 111.978 123.612 1.00 68.78 ? 268 ASN C N   1 
ATOM   5688 C CA  . ASN C 3 286 ? 154.943 112.740 124.701 1.00 73.56 ? 268 ASN C CA  1 
ATOM   5689 C C   . ASN C 3 286 ? 153.512 113.165 124.390 1.00 71.60 ? 268 ASN C C   1 
ATOM   5690 O O   . ASN C 3 286 ? 152.768 113.521 125.312 1.00 69.08 ? 268 ASN C O   1 
ATOM   5691 C CB  . ASN C 3 286 ? 155.796 113.969 125.017 1.00 70.77 ? 268 ASN C CB  1 
ATOM   5692 C CG  . ASN C 3 286 ? 157.157 113.605 125.575 1.00 72.29 ? 268 ASN C CG  1 
ATOM   5693 O OD1 . ASN C 3 286 ? 157.350 112.516 126.115 1.00 73.34 ? 268 ASN C OD1 1 
ATOM   5694 N ND2 . ASN C 3 286 ? 158.108 114.523 125.458 1.00 70.43 ? 268 ASN C ND2 1 
ATOM   5695 N N   . ILE C 3 287 ? 153.108 113.137 123.120 1.00 65.04 ? 269 ILE C N   1 
ATOM   5696 C CA  . ILE C 3 287 ? 151.778 113.567 122.693 1.00 66.49 ? 269 ILE C CA  1 
ATOM   5697 C C   . ILE C 3 287 ? 151.029 112.354 122.160 1.00 65.72 ? 269 ILE C C   1 
ATOM   5698 O O   . ILE C 3 287 ? 151.541 111.624 121.302 1.00 63.40 ? 269 ILE C O   1 
ATOM   5699 C CB  . ILE C 3 287 ? 151.846 114.688 121.639 1.00 61.79 ? 269 ILE C CB  1 
ATOM   5700 C CG1 . ILE C 3 287 ? 152.911 114.396 120.575 1.00 56.53 ? 269 ILE C CG1 1 
ATOM   5701 C CG2 . ILE C 3 287 ? 152.115 116.032 122.312 1.00 61.27 ? 269 ILE C CG2 1 
ATOM   5702 C CD1 . ILE C 3 287 ? 152.844 115.303 119.372 1.00 56.48 ? 269 ILE C CD1 1 
ATOM   5703 N N   . ILE C 3 288 ? 149.824 112.132 122.685 1.00 68.13 ? 270 ILE C N   1 
ATOM   5704 C CA  . ILE C 3 288 ? 148.954 111.044 122.249 1.00 66.62 ? 270 ILE C CA  1 
ATOM   5705 C C   . ILE C 3 288 ? 147.545 111.570 121.991 1.00 67.58 ? 270 ILE C C   1 
ATOM   5706 O O   . ILE C 3 288 ? 146.595 110.786 121.886 1.00 67.91 ? 270 ILE C O   1 
ATOM   5707 C CB  . ILE C 3 288 ? 148.934 109.908 123.290 1.00 69.47 ? 270 ILE C CB  1 
ATOM   5708 C CG1 . ILE C 3 288 ? 148.690 110.464 124.700 1.00 68.69 ? 270 ILE C CG1 1 
ATOM   5709 C CG2 . ILE C 3 288 ? 150.245 109.134 123.250 1.00 67.13 ? 270 ILE C CG2 1 
ATOM   5710 C CD1 . ILE C 3 288 ? 148.362 109.404 125.732 1.00 67.70 ? 270 ILE C CD1 1 
ATOM   5711 N N   . CYS C 3 289 ? 147.399 112.890 121.873 1.00 57.81 ? 271 CYS C N   1 
ATOM   5712 C CA  . CYS C 3 289 ? 146.102 113.539 121.775 1.00 58.37 ? 271 CYS C CA  1 
ATOM   5713 C C   . CYS C 3 289 ? 145.848 113.987 120.339 1.00 59.48 ? 271 CYS C C   1 
ATOM   5714 O O   . CYS C 3 289 ? 146.734 113.966 119.484 1.00 63.27 ? 271 CYS C O   1 
ATOM   5715 C CB  . CYS C 3 289 ? 146.035 114.717 122.744 1.00 55.19 ? 271 CYS C CB  1 
ATOM   5716 S SG  . CYS C 3 289 ? 147.454 115.812 122.641 1.00 64.78 ? 271 CYS C SG  1 
ATOM   5717 N N   . GLY C 3 290 ? 144.614 114.415 120.075 1.00 50.72 ? 272 GLY C N   1 
ATOM   5718 C CA  . GLY C 3 290 ? 144.197 114.689 118.718 1.00 45.13 ? 272 GLY C CA  1 
ATOM   5719 C C   . GLY C 3 290 ? 144.689 116.021 118.182 1.00 43.01 ? 272 GLY C C   1 
ATOM   5720 O O   . GLY C 3 290 ? 145.215 116.856 118.913 1.00 46.76 ? 272 GLY C O   1 
ATOM   5721 N N   . ILE C 3 291 ? 144.498 116.200 116.875 1.00 33.23 ? 273 ILE C N   1 
ATOM   5722 C CA  . ILE C 3 291 ? 144.943 117.380 116.140 1.00 28.65 ? 273 ILE C CA  1 
ATOM   5723 C C   . ILE C 3 291 ? 143.722 118.025 115.502 1.00 29.01 ? 273 ILE C C   1 
ATOM   5724 O O   . ILE C 3 291 ? 142.905 117.335 114.883 1.00 40.08 ? 273 ILE C O   1 
ATOM   5725 C CB  . ILE C 3 291 ? 145.992 117.019 115.072 1.00 19.73 ? 273 ILE C CB  1 
ATOM   5726 C CG1 . ILE C 3 291 ? 147.281 116.542 115.746 1.00 31.73 ? 273 ILE C CG1 1 
ATOM   5727 C CG2 . ILE C 3 291 ? 146.260 118.216 114.163 1.00 17.83 ? 273 ILE C CG2 1 
ATOM   5728 C CD1 . ILE C 3 291 ? 148.239 115.824 114.827 1.00 37.41 ? 273 ILE C CD1 1 
ATOM   5729 N N   . THR C 3 292 ? 143.606 119.347 115.651 1.00 22.40 ? 274 THR C N   1 
ATOM   5730 C CA  . THR C 3 292 ? 142.435 120.089 115.205 1.00 31.62 ? 274 THR C CA  1 
ATOM   5731 C C   . THR C 3 292 ? 142.679 120.970 113.990 1.00 34.89 ? 274 THR C C   1 
ATOM   5732 O O   . THR C 3 292 ? 141.735 121.212 113.231 1.00 36.20 ? 274 THR C O   1 
ATOM   5733 C CB  . THR C 3 292 ? 141.912 120.978 116.340 1.00 28.28 ? 274 THR C CB  1 
ATOM   5734 O OG1 . THR C 3 292 ? 143.011 121.650 116.964 1.00 38.77 ? 274 THR C OG1 1 
ATOM   5735 C CG2 . THR C 3 292 ? 141.184 120.149 117.370 1.00 30.87 ? 274 THR C CG2 1 
ATOM   5736 N N   . SER C 3 293 ? 143.899 121.462 113.790 1.00 25.97 ? 275 SER C N   1 
ATOM   5737 C CA  . SER C 3 293 ? 144.171 122.385 112.698 1.00 22.46 ? 275 SER C CA  1 
ATOM   5738 C C   . SER C 3 293 ? 145.646 122.318 112.343 1.00 27.38 ? 275 SER C C   1 
ATOM   5739 O O   . SER C 3 293 ? 146.487 122.106 113.218 1.00 37.94 ? 275 SER C O   1 
ATOM   5740 C CB  . SER C 3 293 ? 143.788 123.819 113.077 1.00 33.19 ? 275 SER C CB  1 
ATOM   5741 O OG  . SER C 3 293 ? 142.445 123.887 113.516 1.00 37.72 ? 275 SER C OG  1 
ATOM   5742 N N   . VAL C 3 294 ? 145.945 122.492 111.056 1.00 12.93 ? 276 VAL C N   1 
ATOM   5743 C CA  . VAL C 3 294 ? 147.311 122.592 110.565 1.00 16.85 ? 276 VAL C CA  1 
ATOM   5744 C C   . VAL C 3 294 ? 147.364 123.705 109.531 1.00 22.41 ? 276 VAL C C   1 
ATOM   5745 O O   . VAL C 3 294 ? 146.392 123.977 108.823 1.00 22.79 ? 276 VAL C O   1 
ATOM   5746 C CB  . VAL C 3 294 ? 147.826 121.271 109.953 1.00 23.69 ? 276 VAL C CB  1 
ATOM   5747 C CG1 . VAL C 3 294 ? 147.682 120.131 110.942 1.00 25.69 ? 276 VAL C CG1 1 
ATOM   5748 C CG2 . VAL C 3 294 ? 147.097 120.957 108.658 1.00 27.03 ? 276 VAL C CG2 1 
ATOM   5749 N N   . SER C 3 295 ? 148.521 124.358 109.457 1.00 23.97 ? 277 SER C N   1 
ATOM   5750 C CA  . SER C 3 295 ? 148.754 125.388 108.458 1.00 22.64 ? 277 SER C CA  1 
ATOM   5751 C C   . SER C 3 295 ? 150.247 125.484 108.196 1.00 20.45 ? 277 SER C C   1 
ATOM   5752 O O   . SER C 3 295 ? 151.063 125.057 109.015 1.00 26.99 ? 277 SER C O   1 
ATOM   5753 C CB  . SER C 3 295 ? 148.207 126.746 108.899 1.00 26.20 ? 277 SER C CB  1 
ATOM   5754 O OG  . SER C 3 295 ? 146.841 126.653 109.257 1.00 31.13 ? 277 SER C OG  1 
ATOM   5755 N N   . PHE C 3 296 ? 150.585 126.050 107.045 1.00 20.01 ? 278 PHE C N   1 
ATOM   5756 C CA  . PHE C 3 296 ? 151.958 126.195 106.594 1.00 21.35 ? 278 PHE C CA  1 
ATOM   5757 C C   . PHE C 3 296 ? 152.400 127.646 106.730 1.00 27.58 ? 278 PHE C C   1 
ATOM   5758 O O   . PHE C 3 296 ? 151.590 128.574 106.735 1.00 32.85 ? 278 PHE C O   1 
ATOM   5759 C CB  . PHE C 3 296 ? 152.091 125.737 105.141 1.00 23.64 ? 278 PHE C CB  1 
ATOM   5760 C CG  . PHE C 3 296 ? 152.449 124.291 104.989 1.00 21.95 ? 278 PHE C CG  1 
ATOM   5761 C CD1 . PHE C 3 296 ? 153.743 123.859 105.196 1.00 28.07 ? 278 PHE C CD1 1 
ATOM   5762 C CD2 . PHE C 3 296 ? 151.490 123.362 104.638 1.00 18.83 ? 278 PHE C CD2 1 
ATOM   5763 C CE1 . PHE C 3 296 ? 154.072 122.529 105.053 1.00 25.56 ? 278 PHE C CE1 1 
ATOM   5764 C CE2 . PHE C 3 296 ? 151.815 122.033 104.496 1.00 22.77 ? 278 PHE C CE2 1 
ATOM   5765 C CZ  . PHE C 3 296 ? 153.106 121.617 104.702 1.00 14.84 ? 278 PHE C CZ  1 
ATOM   5766 N N   . SER C 3 297 ? 153.710 127.832 106.839 1.00 31.82 ? 279 SER C N   1 
ATOM   5767 C CA  . SER C 3 297 ? 154.289 129.162 106.872 1.00 27.61 ? 279 SER C CA  1 
ATOM   5768 C C   . SER C 3 297 ? 154.402 129.691 105.445 1.00 29.92 ? 279 SER C C   1 
ATOM   5769 O O   . SER C 3 297 ? 154.017 129.027 104.481 1.00 38.00 ? 279 SER C O   1 
ATOM   5770 C CB  . SER C 3 297 ? 155.641 129.131 107.578 1.00 28.22 ? 279 SER C CB  1 
ATOM   5771 O OG  . SER C 3 297 ? 156.413 130.266 107.246 1.00 26.83 ? 279 SER C OG  1 
ATOM   5772 N N   . LYS C 3 298 ? 154.925 130.910 105.301 1.00 25.19 ? 280 LYS C N   1 
ATOM   5773 C CA  . LYS C 3 298 ? 154.980 131.537 103.983 1.00 24.77 ? 280 LYS C CA  1 
ATOM   5774 C C   . LYS C 3 298 ? 155.880 130.754 103.034 1.00 30.49 ? 280 LYS C C   1 
ATOM   5775 O O   . LYS C 3 298 ? 155.532 130.547 101.866 1.00 35.01 ? 280 LYS C O   1 
ATOM   5776 C CB  . LYS C 3 298 ? 155.457 132.986 104.114 1.00 38.57 ? 280 LYS C CB  1 
ATOM   5777 C CG  . LYS C 3 298 ? 155.486 133.783 102.808 1.00 37.03 ? 280 LYS C CG  1 
ATOM   5778 C CD  . LYS C 3 298 ? 154.094 133.903 102.184 1.00 33.96 ? 280 LYS C CD  1 
ATOM   5779 C CE  . LYS C 3 298 ? 154.010 134.931 101.054 1.00 32.68 ? 280 LYS C CE  1 
ATOM   5780 N NZ  . LYS C 3 298 ? 154.686 136.231 101.325 1.00 28.41 ? 280 LYS C NZ  1 
ATOM   5781 N N   . SER C 3 299 ? 157.017 130.270 103.545 1.00 34.52 ? 281 SER C N   1 
ATOM   5782 C CA  . SER C 3 299 ? 157.970 129.501 102.698 1.00 33.10 ? 281 SER C CA  1 
ATOM   5783 C C   . SER C 3 299 ? 157.694 127.995 102.805 1.00 32.69 ? 281 SER C C   1 
ATOM   5784 O O   . SER C 3 299 ? 158.348 127.226 102.066 1.00 37.67 ? 281 SER C O   1 
ATOM   5785 C CB  . SER C 3 299 ? 159.399 129.810 103.063 1.00 38.70 ? 281 SER C CB  1 
ATOM   5786 O OG  . SER C 3 299 ? 159.706 129.323 104.362 1.00 46.63 ? 281 SER C OG  1 
ATOM   5787 N N   . GLY C 3 300 ? 156.773 127.587 103.684 1.00 34.58 ? 282 GLY C N   1 
ATOM   5788 C CA  . GLY C 3 300 ? 156.493 126.181 103.868 1.00 34.59 ? 282 GLY C CA  1 
ATOM   5789 C C   . GLY C 3 300 ? 157.503 125.439 104.712 1.00 33.09 ? 282 GLY C C   1 
ATOM   5790 O O   . GLY C 3 300 ? 157.293 124.255 104.997 1.00 35.81 ? 282 GLY C O   1 
ATOM   5791 N N   . ARG C 3 301 ? 158.591 126.094 105.127 1.00 36.46 ? 283 ARG C N   1 
ATOM   5792 C CA  . ARG C 3 301 ? 159.584 125.426 105.960 1.00 38.04 ? 283 ARG C CA  1 
ATOM   5793 C C   . ARG C 3 301 ? 159.007 125.036 107.313 1.00 36.63 ? 283 ARG C C   1 
ATOM   5794 O O   . ARG C 3 301 ? 159.422 124.025 107.890 1.00 44.21 ? 283 ARG C O   1 
ATOM   5795 C CB  . ARG C 3 301 ? 160.808 126.328 106.138 1.00 35.61 ? 283 ARG C CB  1 
ATOM   5796 C CG  . ARG C 3 301 ? 161.936 125.769 107.018 1.00 35.34 ? 283 ARG C CG  1 
ATOM   5797 C CD  . ARG C 3 301 ? 162.482 124.436 106.525 1.00 38.88 ? 283 ARG C CD  1 
ATOM   5798 N NE  . ARG C 3 301 ? 163.471 123.882 107.447 1.00 32.31 ? 283 ARG C NE  1 
ATOM   5799 C CZ  . ARG C 3 301 ? 164.790 123.930 107.296 1.00 40.35 ? 283 ARG C CZ  1 
ATOM   5800 N NH1 . ARG C 3 301 ? 165.360 124.561 106.280 1.00 40.74 ? 283 ARG C NH1 1 
ATOM   5801 N NH2 . ARG C 3 301 ? 165.564 123.333 108.197 1.00 46.35 ? 283 ARG C NH2 1 
ATOM   5802 N N   . LEU C 3 302 ? 158.060 125.813 107.827 1.00 24.68 ? 284 LEU C N   1 
ATOM   5803 C CA  . LEU C 3 302 ? 157.426 125.560 109.111 1.00 27.30 ? 284 LEU C CA  1 
ATOM   5804 C C   . LEU C 3 302 ? 156.012 125.037 108.902 1.00 26.22 ? 284 LEU C C   1 
ATOM   5805 O O   . LEU C 3 302 ? 155.213 125.618 108.164 1.00 32.42 ? 284 LEU C O   1 
ATOM   5806 C CB  . LEU C 3 302 ? 157.391 126.835 109.959 1.00 29.87 ? 284 LEU C CB  1 
ATOM   5807 C CG  . LEU C 3 302 ? 158.312 126.852 111.180 1.00 27.47 ? 284 LEU C CG  1 
ATOM   5808 C CD1 . LEU C 3 302 ? 159.770 126.714 110.778 1.00 32.82 ? 284 LEU C CD1 1 
ATOM   5809 C CD2 . LEU C 3 302 ? 158.096 128.123 111.981 1.00 33.83 ? 284 LEU C CD2 1 
ATOM   5810 N N   . LEU C 3 303 ? 155.716 123.923 109.570 1.00 25.88 ? 285 LEU C N   1 
ATOM   5811 C CA  . LEU C 3 303 ? 154.385 123.326 109.571 1.00 24.00 ? 285 LEU C CA  1 
ATOM   5812 C C   . LEU C 3 303 ? 153.800 123.506 110.959 1.00 23.19 ? 285 LEU C C   1 
ATOM   5813 O O   . LEU C 3 303 ? 154.268 122.882 111.915 1.00 37.03 ? 285 LEU C O   1 
ATOM   5814 C CB  . LEU C 3 303 ? 154.434 121.840 109.196 1.00 26.93 ? 285 LEU C CB  1 
ATOM   5815 C CG  . LEU C 3 303 ? 153.105 121.070 109.239 1.00 23.58 ? 285 LEU C CG  1 
ATOM   5816 C CD1 . LEU C 3 303 ? 153.005 120.115 108.067 1.00 20.98 ? 285 LEU C CD1 1 
ATOM   5817 C CD2 . LEU C 3 303 ? 152.936 120.296 110.542 1.00 38.74 ? 285 LEU C CD2 1 
ATOM   5818 N N   . LEU C 3 304 ? 152.795 124.362 111.069 1.00 18.90 ? 286 LEU C N   1 
ATOM   5819 C CA  . LEU C 3 304 ? 152.131 124.568 112.341 1.00 26.87 ? 286 LEU C CA  1 
ATOM   5820 C C   . LEU C 3 304 ? 151.099 123.470 112.570 1.00 28.01 ? 286 LEU C C   1 
ATOM   5821 O O   . LEU C 3 304 ? 150.755 122.705 111.666 1.00 43.12 ? 286 LEU C O   1 
ATOM   5822 C CB  . LEU C 3 304 ? 151.476 125.947 112.383 1.00 30.92 ? 286 LEU C CB  1 
ATOM   5823 C CG  . LEU C 3 304 ? 152.398 127.124 112.707 1.00 26.33 ? 286 LEU C CG  1 
ATOM   5824 C CD1 . LEU C 3 304 ? 153.472 127.324 111.652 1.00 27.21 ? 286 LEU C CD1 1 
ATOM   5825 C CD2 . LEU C 3 304 ? 151.583 128.377 112.855 1.00 23.61 ? 286 LEU C CD2 1 
ATOM   5826 N N   . ALA C 3 305 ? 150.604 123.393 113.800 1.00 16.81 ? 287 ALA C N   1 
ATOM   5827 C CA  . ALA C 3 305 ? 149.605 122.397 114.156 1.00 16.95 ? 287 ALA C CA  1 
ATOM   5828 C C   . ALA C 3 305 ? 148.838 122.897 115.367 1.00 21.22 ? 287 ALA C C   1 
ATOM   5829 O O   . ALA C 3 305 ? 149.259 123.837 116.043 1.00 39.50 ? 287 ALA C O   1 
ATOM   5830 C CB  . ALA C 3 305 ? 150.246 121.037 114.441 1.00 22.77 ? 287 ALA C CB  1 
ATOM   5831 N N   . GLY C 3 306 ? 147.696 122.264 115.619 1.00 16.78 ? 288 GLY C N   1 
ATOM   5832 C CA  . GLY C 3 306 ? 146.893 122.569 116.786 1.00 24.44 ? 288 GLY C CA  1 
ATOM   5833 C C   . GLY C 3 306 ? 146.352 121.304 117.412 1.00 36.20 ? 288 GLY C C   1 
ATOM   5834 O O   . GLY C 3 306 ? 145.626 120.549 116.759 1.00 54.10 ? 288 GLY C O   1 
ATOM   5835 N N   . TYR C 3 307 ? 146.683 121.073 118.677 1.00 28.55 ? 289 TYR C N   1 
ATOM   5836 C CA  . TYR C 3 307 ? 146.419 119.814 119.356 1.00 31.03 ? 289 TYR C CA  1 
ATOM   5837 C C   . TYR C 3 307 ? 145.341 119.996 120.417 1.00 38.86 ? 289 TYR C C   1 
ATOM   5838 O O   . TYR C 3 307 ? 144.878 121.105 120.688 1.00 43.12 ? 289 TYR C O   1 
ATOM   5839 C CB  . TYR C 3 307 ? 147.704 119.269 119.990 1.00 33.47 ? 289 TYR C CB  1 
ATOM   5840 C CG  . TYR C 3 307 ? 148.734 118.796 118.993 1.00 30.03 ? 289 TYR C CG  1 
ATOM   5841 C CD1 . TYR C 3 307 ? 149.469 119.697 118.240 1.00 33.38 ? 289 TYR C CD1 1 
ATOM   5842 C CD2 . TYR C 3 307 ? 148.977 117.445 118.813 1.00 37.98 ? 289 TYR C CD2 1 
ATOM   5843 C CE1 . TYR C 3 307 ? 150.409 119.265 117.332 1.00 36.39 ? 289 TYR C CE1 1 
ATOM   5844 C CE2 . TYR C 3 307 ? 149.918 117.004 117.909 1.00 42.67 ? 289 TYR C CE2 1 
ATOM   5845 C CZ  . TYR C 3 307 ? 150.632 117.919 117.170 1.00 38.27 ? 289 TYR C CZ  1 
ATOM   5846 O OH  . TYR C 3 307 ? 151.572 117.485 116.265 1.00 33.47 ? 289 TYR C OH  1 
ATOM   5847 N N   . ASP C 3 308 ? 144.943 118.874 121.014 1.00 51.36 ? 290 ASP C N   1 
ATOM   5848 C CA  . ASP C 3 308 ? 144.007 118.869 122.131 1.00 51.82 ? 290 ASP C CA  1 
ATOM   5849 C C   . ASP C 3 308 ? 144.699 118.988 123.484 1.00 50.97 ? 290 ASP C C   1 
ATOM   5850 O O   . ASP C 3 308 ? 144.028 118.871 124.516 1.00 53.04 ? 290 ASP C O   1 
ATOM   5851 C CB  . ASP C 3 308 ? 143.160 117.595 122.089 1.00 49.46 ? 290 ASP C CB  1 
ATOM   5852 C CG  . ASP C 3 308 ? 142.092 117.647 121.023 1.00 50.67 ? 290 ASP C CG  1 
ATOM   5853 O OD1 . ASP C 3 308 ? 141.326 118.629 121.009 1.00 48.04 ? 290 ASP C OD1 1 
ATOM   5854 O OD2 . ASP C 3 308 ? 142.017 116.711 120.200 1.00 51.11 ? 290 ASP C OD2 1 
ATOM   5855 N N   . ASP C 3 309 ? 146.011 119.236 123.510 1.00 52.10 ? 291 ASP C N   1 
ATOM   5856 C CA  . ASP C 3 309 ? 146.771 119.398 124.743 1.00 49.42 ? 291 ASP C CA  1 
ATOM   5857 C C   . ASP C 3 309 ? 146.717 120.817 125.292 1.00 53.55 ? 291 ASP C C   1 
ATOM   5858 O O   . ASP C 3 309 ? 147.627 121.205 126.033 1.00 53.44 ? 291 ASP C O   1 
ATOM   5859 C CB  . ASP C 3 309 ? 148.231 118.999 124.517 1.00 44.56 ? 291 ASP C CB  1 
ATOM   5860 N N   . PHE C 3 310 ? 145.699 121.603 124.938 1.00 57.16 ? 292 PHE C N   1 
ATOM   5861 C CA  . PHE C 3 310 ? 145.565 122.992 125.359 1.00 60.35 ? 292 PHE C CA  1 
ATOM   5862 C C   . PHE C 3 310 ? 146.724 123.849 124.870 1.00 55.46 ? 292 PHE C C   1 
ATOM   5863 O O   . PHE C 3 310 ? 147.082 124.838 125.516 1.00 58.98 ? 292 PHE C O   1 
ATOM   5864 C CB  . PHE C 3 310 ? 145.447 123.110 126.889 1.00 58.75 ? 292 PHE C CB  1 
ATOM   5865 C CG  . PHE C 3 310 ? 144.308 122.318 127.498 1.00 56.39 ? 292 PHE C CG  1 
ATOM   5866 C CD1 . PHE C 3 310 ? 143.193 121.948 126.757 1.00 55.64 ? 292 PHE C CD1 1 
ATOM   5867 C CD2 . PHE C 3 310 ? 144.367 121.941 128.828 1.00 56.88 ? 292 PHE C CD2 1 
ATOM   5868 C CE1 . PHE C 3 310 ? 142.167 121.227 127.334 1.00 57.50 ? 292 PHE C CE1 1 
ATOM   5869 C CE2 . PHE C 3 310 ? 143.342 121.218 129.407 1.00 58.93 ? 292 PHE C CE2 1 
ATOM   5870 C CZ  . PHE C 3 310 ? 142.243 120.861 128.659 1.00 58.87 ? 292 PHE C CZ  1 
ATOM   5871 N N   . ASN C 3 311 ? 147.325 123.491 123.739 1.00 40.22 ? 293 ASN C N   1 
ATOM   5872 C CA  . ASN C 3 311 ? 148.467 124.221 123.209 1.00 46.20 ? 293 ASN C CA  1 
ATOM   5873 C C   . ASN C 3 311 ? 148.592 123.906 121.723 1.00 41.57 ? 293 ASN C C   1 
ATOM   5874 O O   . ASN C 3 311 ? 147.745 123.226 121.138 1.00 46.26 ? 293 ASN C O   1 
ATOM   5875 C CB  . ASN C 3 311 ? 149.748 123.865 123.970 1.00 47.42 ? 293 ASN C CB  1 
ATOM   5876 C CG  . ASN C 3 311 ? 150.196 122.437 123.726 1.00 47.79 ? 293 ASN C CG  1 
ATOM   5877 O OD1 . ASN C 3 311 ? 149.392 121.571 123.378 1.00 47.13 ? 293 ASN C OD1 1 
ATOM   5878 N ND2 . ASN C 3 311 ? 151.487 122.184 123.905 1.00 46.93 ? 293 ASN C ND2 1 
ATOM   5879 N N   . CYS C 3 312 ? 149.661 124.417 121.118 1.00 36.46 ? 294 CYS C N   1 
ATOM   5880 C CA  . CYS C 3 312 ? 149.990 124.184 119.721 1.00 35.19 ? 294 CYS C CA  1 
ATOM   5881 C C   . CYS C 3 312 ? 151.439 123.735 119.627 1.00 39.80 ? 294 CYS C C   1 
ATOM   5882 O O   . CYS C 3 312 ? 152.167 123.700 120.622 1.00 48.98 ? 294 CYS C O   1 
ATOM   5883 C CB  . CYS C 3 312 ? 149.772 125.445 118.874 1.00 33.64 ? 294 CYS C CB  1 
ATOM   5884 S SG  . CYS C 3 312 ? 148.116 126.153 118.976 1.00 46.96 ? 294 CYS C SG  1 
ATOM   5885 N N   . ASN C 3 313 ? 151.854 123.390 118.412 1.00 28.82 ? 295 ASN C N   1 
ATOM   5886 C CA  . ASN C 3 313 ? 153.221 122.987 118.120 1.00 29.19 ? 295 ASN C CA  1 
ATOM   5887 C C   . ASN C 3 313 ? 153.655 123.633 116.813 1.00 33.75 ? 295 ASN C C   1 
ATOM   5888 O O   . ASN C 3 313 ? 152.834 124.120 116.033 1.00 41.93 ? 295 ASN C O   1 
ATOM   5889 C CB  . ASN C 3 313 ? 153.352 121.462 118.025 1.00 33.10 ? 295 ASN C CB  1 
ATOM   5890 C CG  . ASN C 3 313 ? 153.501 120.801 119.381 1.00 40.88 ? 295 ASN C CG  1 
ATOM   5891 O OD1 . ASN C 3 313 ? 152.770 121.111 120.319 1.00 46.23 ? 295 ASN C OD1 1 
ATOM   5892 N ND2 . ASN C 3 313 ? 154.447 119.878 119.487 1.00 37.46 ? 295 ASN C ND2 1 
ATOM   5893 N N   . VAL C 3 314 ? 154.966 123.649 116.591 1.00 31.76 ? 296 VAL C N   1 
ATOM   5894 C CA  . VAL C 3 314 ? 155.560 124.143 115.354 1.00 30.72 ? 296 VAL C CA  1 
ATOM   5895 C C   . VAL C 3 314 ? 156.550 123.094 114.876 1.00 35.89 ? 296 VAL C C   1 
ATOM   5896 O O   . VAL C 3 314 ? 157.564 122.847 115.539 1.00 37.56 ? 296 VAL C O   1 
ATOM   5897 C CB  . VAL C 3 314 ? 156.249 125.503 115.550 1.00 35.83 ? 296 VAL C CB  1 
ATOM   5898 C CG1 . VAL C 3 314 ? 157.099 125.857 114.345 1.00 36.13 ? 296 VAL C CG1 1 
ATOM   5899 C CG2 . VAL C 3 314 ? 155.214 126.584 115.806 1.00 39.32 ? 296 VAL C CG2 1 
ATOM   5900 N N   . TRP C 3 315 ? 156.263 122.489 113.727 1.00 34.91 ? 297 TRP C N   1 
ATOM   5901 C CA  . TRP C 3 315 ? 157.037 121.379 113.190 1.00 30.51 ? 297 TRP C CA  1 
ATOM   5902 C C   . TRP C 3 315 ? 157.904 121.852 112.034 1.00 28.73 ? 297 TRP C C   1 
ATOM   5903 O O   . TRP C 3 315 ? 157.435 122.570 111.148 1.00 39.51 ? 297 TRP C O   1 
ATOM   5904 C CB  . TRP C 3 315 ? 156.117 120.257 112.705 1.00 27.26 ? 297 TRP C CB  1 
ATOM   5905 C CG  . TRP C 3 315 ? 155.422 119.529 113.804 1.00 30.37 ? 297 TRP C CG  1 
ATOM   5906 C CD1 . TRP C 3 315 ? 154.155 119.743 114.256 1.00 29.46 ? 297 TRP C CD1 1 
ATOM   5907 C CD2 . TRP C 3 315 ? 155.956 118.462 114.593 1.00 35.95 ? 297 TRP C CD2 1 
ATOM   5908 N NE1 . TRP C 3 315 ? 153.866 118.875 115.279 1.00 38.40 ? 297 TRP C NE1 1 
ATOM   5909 C CE2 . TRP C 3 315 ? 154.956 118.078 115.505 1.00 37.90 ? 297 TRP C CE2 1 
ATOM   5910 C CE3 . TRP C 3 315 ? 157.183 117.794 114.617 1.00 31.80 ? 297 TRP C CE3 1 
ATOM   5911 C CZ2 . TRP C 3 315 ? 155.145 117.058 116.431 1.00 39.21 ? 297 TRP C CZ2 1 
ATOM   5912 C CZ3 . TRP C 3 315 ? 157.368 116.783 115.535 1.00 30.17 ? 297 TRP C CZ3 1 
ATOM   5913 C CH2 . TRP C 3 315 ? 156.356 116.424 116.429 1.00 37.60 ? 297 TRP C CH2 1 
ATOM   5914 N N   . ASP C 3 316 ? 159.169 121.445 112.046 1.00 26.99 ? 298 ASP C N   1 
ATOM   5915 C CA  . ASP C 3 316 ? 160.038 121.705 110.908 1.00 27.09 ? 298 ASP C CA  1 
ATOM   5916 C C   . ASP C 3 316 ? 159.648 120.784 109.761 1.00 33.30 ? 298 ASP C C   1 
ATOM   5917 O O   . ASP C 3 316 ? 159.696 119.558 109.892 1.00 47.21 ? 298 ASP C O   1 
ATOM   5918 C CB  . ASP C 3 316 ? 161.498 121.490 111.295 1.00 40.12 ? 298 ASP C CB  1 
ATOM   5919 C CG  . ASP C 3 316 ? 162.460 122.049 110.268 1.00 45.20 ? 298 ASP C CG  1 
ATOM   5920 O OD1 . ASP C 3 316 ? 162.489 121.530 109.135 1.00 42.98 ? 298 ASP C OD1 1 
ATOM   5921 O OD2 . ASP C 3 316 ? 163.189 123.008 110.594 1.00 43.71 ? 298 ASP C OD2 1 
ATOM   5922 N N   . ALA C 3 317 ? 159.269 121.376 108.628 1.00 34.98 ? 299 ALA C N   1 
ATOM   5923 C CA  . ALA C 3 317 ? 158.672 120.610 107.540 1.00 36.03 ? 299 ALA C CA  1 
ATOM   5924 C C   . ALA C 3 317 ? 159.650 119.665 106.853 1.00 41.40 ? 299 ALA C C   1 
ATOM   5925 O O   . ALA C 3 317 ? 159.199 118.794 106.102 1.00 48.11 ? 299 ALA C O   1 
ATOM   5926 C CB  . ALA C 3 317 ? 158.077 121.559 106.500 1.00 35.43 ? 299 ALA C CB  1 
ATOM   5927 N N   . LEU C 3 318 ? 160.959 119.805 107.090 1.00 41.41 ? 300 LEU C N   1 
ATOM   5928 C CA  . LEU C 3 318 ? 161.970 118.984 106.435 1.00 42.88 ? 300 LEU C CA  1 
ATOM   5929 C C   . LEU C 3 318 ? 162.679 118.006 107.359 1.00 42.60 ? 300 LEU C C   1 
ATOM   5930 O O   . LEU C 3 318 ? 163.373 117.117 106.856 1.00 47.54 ? 300 LEU C O   1 
ATOM   5931 C CB  . LEU C 3 318 ? 163.031 119.871 105.764 1.00 45.24 ? 300 LEU C CB  1 
ATOM   5932 C CG  . LEU C 3 318 ? 162.719 120.419 104.368 1.00 44.59 ? 300 LEU C CG  1 
ATOM   5933 C CD1 . LEU C 3 318 ? 161.372 121.114 104.307 1.00 38.87 ? 300 LEU C CD1 1 
ATOM   5934 C CD2 . LEU C 3 318 ? 163.827 121.363 103.924 1.00 43.77 ? 300 LEU C CD2 1 
ATOM   5935 N N   . LYS C 3 319 ? 162.536 118.139 108.680 1.00 41.59 ? 301 LYS C N   1 
ATOM   5936 C CA  . LYS C 3 319 ? 163.201 117.256 109.631 1.00 49.67 ? 301 LYS C CA  1 
ATOM   5937 C C   . LYS C 3 319 ? 162.276 116.660 110.680 1.00 55.57 ? 301 LYS C C   1 
ATOM   5938 O O   . LYS C 3 319 ? 162.706 115.752 111.400 1.00 57.16 ? 301 LYS C O   1 
ATOM   5939 C CB  . LYS C 3 319 ? 164.338 117.999 110.346 1.00 48.81 ? 301 LYS C CB  1 
ATOM   5940 C CG  . LYS C 3 319 ? 165.464 118.423 109.424 1.00 48.70 ? 301 LYS C CG  1 
ATOM   5941 C CD  . LYS C 3 319 ? 166.586 119.097 110.203 1.00 50.54 ? 301 LYS C CD  1 
ATOM   5942 C CE  . LYS C 3 319 ? 167.788 119.448 109.330 1.00 54.08 ? 301 LYS C CE  1 
ATOM   5943 N NZ  . LYS C 3 319 ? 168.241 118.336 108.447 1.00 54.05 ? 301 LYS C NZ  1 
ATOM   5944 N N   . ALA C 3 320 ? 161.032 117.126 110.787 1.00 49.14 ? 302 ALA C N   1 
ATOM   5945 C CA  . ALA C 3 320 ? 160.075 116.608 111.762 1.00 41.21 ? 302 ALA C CA  1 
ATOM   5946 C C   . ALA C 3 320 ? 160.604 116.756 113.188 1.00 46.39 ? 302 ALA C C   1 
ATOM   5947 O O   . ALA C 3 320 ? 160.440 115.873 114.032 1.00 55.22 ? 302 ALA C O   1 
ATOM   5948 C CB  . ALA C 3 320 ? 159.719 115.151 111.458 1.00 33.82 ? 302 ALA C CB  1 
ATOM   5949 N N   . ASP C 3 321 ? 161.242 117.895 113.449 1.00 39.34 ? 303 ASP C N   1 
ATOM   5950 C CA  . ASP C 3 321 ? 161.760 118.244 114.765 1.00 40.35 ? 303 ASP C CA  1 
ATOM   5951 C C   . ASP C 3 321 ? 160.874 119.331 115.351 1.00 39.62 ? 303 ASP C C   1 
ATOM   5952 O O   . ASP C 3 321 ? 160.620 120.347 114.697 1.00 41.78 ? 303 ASP C O   1 
ATOM   5953 C CB  . ASP C 3 321 ? 163.209 118.722 114.678 1.00 44.91 ? 303 ASP C CB  1 
ATOM   5954 C CG  . ASP C 3 321 ? 164.173 117.603 114.336 1.00 49.01 ? 303 ASP C CG  1 
ATOM   5955 O OD1 . ASP C 3 321 ? 163.751 116.428 114.335 1.00 43.02 ? 303 ASP C OD1 1 
ATOM   5956 O OD2 . ASP C 3 321 ? 165.356 117.899 114.069 1.00 50.89 ? 303 ASP C OD2 1 
ATOM   5957 N N   . ARG C 3 322 ? 160.404 119.116 116.574 1.00 41.79 ? 304 ARG C N   1 
ATOM   5958 C CA  . ARG C 3 322 ? 159.577 120.110 117.241 1.00 41.46 ? 304 ARG C CA  1 
ATOM   5959 C C   . ARG C 3 322 ? 160.416 121.340 117.554 1.00 48.46 ? 304 ARG C C   1 
ATOM   5960 O O   . ARG C 3 322 ? 161.220 121.330 118.491 1.00 52.42 ? 304 ARG C O   1 
ATOM   5961 C CB  . ARG C 3 322 ? 158.990 119.518 118.520 1.00 46.19 ? 304 ARG C CB  1 
ATOM   5962 C CG  . ARG C 3 322 ? 157.867 120.324 119.140 1.00 45.10 ? 304 ARG C CG  1 
ATOM   5963 C CD  . ARG C 3 322 ? 157.738 120.018 120.625 1.00 50.31 ? 304 ARG C CD  1 
ATOM   5964 N NE  . ARG C 3 322 ? 157.491 118.602 120.881 1.00 52.62 ? 304 ARG C NE  1 
ATOM   5965 C CZ  . ARG C 3 322 ? 157.038 118.104 122.025 1.00 52.66 ? 304 ARG C CZ  1 
ATOM   5966 N NH1 . ARG C 3 322 ? 156.772 118.877 123.067 1.00 51.50 ? 304 ARG C NH1 1 
ATOM   5967 N NH2 . ARG C 3 322 ? 156.854 116.791 122.130 1.00 48.71 ? 304 ARG C NH2 1 
ATOM   5968 N N   . ALA C 3 323 ? 160.223 122.401 116.769 1.00 46.12 ? 305 ALA C N   1 
ATOM   5969 C CA  . ALA C 3 323 ? 161.016 123.621 116.868 1.00 42.97 ? 305 ALA C CA  1 
ATOM   5970 C C   . ALA C 3 323 ? 160.199 124.775 117.437 1.00 47.20 ? 305 ALA C C   1 
ATOM   5971 O O   . ALA C 3 323 ? 160.375 125.924 117.032 1.00 47.66 ? 305 ALA C O   1 
ATOM   5972 C CB  . ALA C 3 323 ? 161.590 123.999 115.504 1.00 33.93 ? 305 ALA C CB  1 
ATOM   5973 N N   . GLY C 3 324 ? 159.311 124.489 118.374 1.00 46.22 ? 306 GLY C N   1 
ATOM   5974 C CA  . GLY C 3 324 ? 158.520 125.525 119.002 1.00 41.61 ? 306 GLY C CA  1 
ATOM   5975 C C   . GLY C 3 324 ? 157.245 124.972 119.586 1.00 41.07 ? 306 GLY C C   1 
ATOM   5976 O O   . GLY C 3 324 ? 156.697 123.968 119.130 1.00 48.53 ? 306 GLY C O   1 
ATOM   5977 N N   . VAL C 3 325 ? 156.775 125.644 120.633 1.00 32.73 ? 307 VAL C N   1 
ATOM   5978 C CA  . VAL C 3 325 ? 155.508 125.331 121.280 1.00 31.87 ? 307 VAL C CA  1 
ATOM   5979 C C   . VAL C 3 325 ? 154.837 126.648 121.635 1.00 35.08 ? 307 VAL C C   1 
ATOM   5980 O O   . VAL C 3 325 ? 155.486 127.562 122.153 1.00 46.47 ? 307 VAL C O   1 
ATOM   5981 C CB  . VAL C 3 325 ? 155.708 124.455 122.535 1.00 39.87 ? 307 VAL C CB  1 
ATOM   5982 C CG1 . VAL C 3 325 ? 154.426 124.396 123.369 1.00 40.97 ? 307 VAL C CG1 1 
ATOM   5983 C CG2 . VAL C 3 325 ? 156.170 123.058 122.145 1.00 39.64 ? 307 VAL C CG2 1 
ATOM   5984 N N   . LEU C 3 326 ? 153.538 126.746 121.353 1.00 33.50 ? 308 LEU C N   1 
ATOM   5985 C CA  . LEU C 3 326 ? 152.747 127.940 121.641 1.00 35.67 ? 308 LEU C CA  1 
ATOM   5986 C C   . LEU C 3 326 ? 151.653 127.559 122.629 1.00 39.24 ? 308 LEU C C   1 
ATOM   5987 O O   . LEU C 3 326 ? 150.533 127.226 122.227 1.00 37.75 ? 308 LEU C O   1 
ATOM   5988 C CB  . LEU C 3 326 ? 152.154 128.530 120.362 1.00 34.41 ? 308 LEU C CB  1 
ATOM   5989 C CG  . LEU C 3 326 ? 153.113 128.681 119.182 1.00 37.74 ? 308 LEU C CG  1 
ATOM   5990 C CD1 . LEU C 3 326 ? 152.380 129.249 117.981 1.00 33.62 ? 308 LEU C CD1 1 
ATOM   5991 C CD2 . LEU C 3 326 ? 154.291 129.559 119.562 1.00 39.36 ? 308 LEU C CD2 1 
ATOM   5992 N N   . ALA C 3 327 ? 151.976 127.622 123.920 1.00 45.45 ? 309 ALA C N   1 
ATOM   5993 C CA  . ALA C 3 327 ? 151.042 127.288 124.991 1.00 43.54 ? 309 ALA C CA  1 
ATOM   5994 C C   . ALA C 3 327 ? 150.512 128.588 125.574 1.00 44.15 ? 309 ALA C C   1 
ATOM   5995 O O   . ALA C 3 327 ? 151.215 129.262 126.333 1.00 45.98 ? 309 ALA C O   1 
ATOM   5996 C CB  . ALA C 3 327 ? 151.717 126.439 126.068 1.00 43.36 ? 309 ALA C CB  1 
ATOM   5997 N N   . GLY C 3 328 ? 149.286 128.947 125.201 1.00 38.68 ? 310 GLY C N   1 
ATOM   5998 C CA  . GLY C 3 328 ? 148.644 130.137 125.724 1.00 39.85 ? 310 GLY C CA  1 
ATOM   5999 C C   . GLY C 3 328 ? 147.154 129.999 125.965 1.00 42.72 ? 310 GLY C C   1 
ATOM   6000 O O   . GLY C 3 328 ? 146.509 130.973 126.365 1.00 43.33 ? 310 GLY C O   1 
ATOM   6001 N N   . HIS C 3 329 ? 146.593 128.814 125.730 1.00 48.84 ? 311 HIS C N   1 
ATOM   6002 C CA  . HIS C 3 329 ? 145.170 128.561 125.887 1.00 51.22 ? 311 HIS C CA  1 
ATOM   6003 C C   . HIS C 3 329 ? 144.945 127.552 127.004 1.00 52.97 ? 311 HIS C C   1 
ATOM   6004 O O   . HIS C 3 329 ? 145.612 126.516 127.069 1.00 55.15 ? 311 HIS C O   1 
ATOM   6005 C CB  . HIS C 3 329 ? 144.560 128.034 124.584 1.00 50.55 ? 311 HIS C CB  1 
ATOM   6006 C CG  . HIS C 3 329 ? 144.664 128.991 123.437 1.00 50.93 ? 311 HIS C CG  1 
ATOM   6007 N ND1 . HIS C 3 329 ? 143.891 130.128 123.341 1.00 46.29 ? 311 HIS C ND1 1 
ATOM   6008 C CD2 . HIS C 3 329 ? 145.450 128.978 122.335 1.00 47.77 ? 311 HIS C CD2 1 
ATOM   6009 C CE1 . HIS C 3 329 ? 144.199 130.776 122.232 1.00 47.62 ? 311 HIS C CE1 1 
ATOM   6010 N NE2 . HIS C 3 329 ? 145.142 130.098 121.602 1.00 46.33 ? 311 HIS C NE2 1 
ATOM   6011 N N   . ASP C 3 330 ? 144.001 127.867 127.890 1.00 67.82 ? 312 ASP C N   1 
ATOM   6012 C CA  . ASP C 3 330 ? 143.602 126.940 128.942 1.00 72.63 ? 312 ASP C CA  1 
ATOM   6013 C C   . ASP C 3 330 ? 142.646 125.862 128.449 1.00 68.98 ? 312 ASP C C   1 
ATOM   6014 O O   . ASP C 3 330 ? 142.434 124.875 129.162 1.00 71.83 ? 312 ASP C O   1 
ATOM   6015 C CB  . ASP C 3 330 ? 142.957 127.694 130.117 1.00 72.76 ? 312 ASP C CB  1 
ATOM   6016 C CG  . ASP C 3 330 ? 141.753 128.517 129.700 1.00 72.65 ? 312 ASP C CG  1 
ATOM   6017 O OD1 . ASP C 3 330 ? 141.473 128.581 128.487 1.00 73.51 ? 312 ASP C OD1 1 
ATOM   6018 O OD2 . ASP C 3 330 ? 141.088 129.095 130.584 1.00 71.33 ? 312 ASP C OD2 1 
ATOM   6019 N N   . ASN C 3 331 ? 142.067 126.027 127.263 1.00 54.14 ? 313 ASN C N   1 
ATOM   6020 C CA  . ASN C 3 331 ? 141.242 125.022 126.605 1.00 58.08 ? 313 ASN C CA  1 
ATOM   6021 C C   . ASN C 3 331 ? 141.891 124.633 125.280 1.00 59.46 ? 313 ASN C C   1 
ATOM   6022 O O   . ASN C 3 331 ? 142.944 125.151 124.901 1.00 54.94 ? 313 ASN C O   1 
ATOM   6023 C CB  . ASN C 3 331 ? 139.819 125.540 126.389 1.00 59.99 ? 313 ASN C CB  1 
ATOM   6024 C CG  . ASN C 3 331 ? 138.772 124.472 126.620 1.00 57.09 ? 313 ASN C CG  1 
ATOM   6025 O OD1 . ASN C 3 331 ? 138.942 123.324 126.209 1.00 53.12 ? 313 ASN C OD1 1 
ATOM   6026 N ND2 . ASN C 3 331 ? 137.680 124.842 127.280 1.00 57.65 ? 313 ASN C ND2 1 
ATOM   6027 N N   . ARG C 3 332 ? 141.252 123.706 124.574 1.00 57.11 ? 314 ARG C N   1 
ATOM   6028 C CA  . ARG C 3 332 ? 141.807 123.203 123.327 1.00 53.63 ? 314 ARG C CA  1 
ATOM   6029 C C   . ARG C 3 332 ? 141.764 124.275 122.243 1.00 48.69 ? 314 ARG C C   1 
ATOM   6030 O O   . ARG C 3 332 ? 140.918 125.172 122.256 1.00 47.50 ? 314 ARG C O   1 
ATOM   6031 C CB  . ARG C 3 332 ? 141.049 121.950 122.874 1.00 50.64 ? 314 ARG C CB  1 
ATOM   6032 C CG  . ARG C 3 332 ? 139.864 122.192 121.939 1.00 44.57 ? 314 ARG C CG  1 
ATOM   6033 C CD  . ARG C 3 332 ? 138.871 121.044 121.998 1.00 51.91 ? 314 ARG C CD  1 
ATOM   6034 N NE  . ARG C 3 332 ? 138.080 120.938 120.774 1.00 55.17 ? 314 ARG C NE  1 
ATOM   6035 C CZ  . ARG C 3 332 ? 138.333 120.126 119.753 1.00 54.25 ? 314 ARG C CZ  1 
ATOM   6036 N NH1 . ARG C 3 332 ? 139.364 119.297 119.753 1.00 52.73 ? 314 ARG C NH1 1 
ATOM   6037 N NH2 . ARG C 3 332 ? 137.520 120.140 118.701 1.00 48.76 ? 314 ARG C NH2 1 
ATOM   6038 N N   . VAL C 3 333 ? 142.694 124.169 121.297 1.00 40.18 ? 315 VAL C N   1 
ATOM   6039 C CA  . VAL C 3 333 ? 142.731 125.051 120.134 1.00 38.94 ? 315 VAL C CA  1 
ATOM   6040 C C   . VAL C 3 333 ? 141.903 124.411 119.028 1.00 40.26 ? 315 VAL C C   1 
ATOM   6041 O O   . VAL C 3 333 ? 142.117 123.247 118.671 1.00 45.16 ? 315 VAL C O   1 
ATOM   6042 C CB  . VAL C 3 333 ? 144.180 125.328 119.680 1.00 31.11 ? 315 VAL C CB  1 
ATOM   6043 C CG1 . VAL C 3 333 ? 144.970 124.048 119.378 1.00 33.36 ? 315 VAL C CG1 1 
ATOM   6044 C CG2 . VAL C 3 333 ? 144.197 126.247 118.471 1.00 31.57 ? 315 VAL C CG2 1 
ATOM   6045 N N   . SER C 3 334 ? 140.935 125.162 118.506 1.00 36.28 ? 316 SER C N   1 
ATOM   6046 C CA  . SER C 3 334 ? 139.994 124.654 117.517 1.00 32.77 ? 316 SER C CA  1 
ATOM   6047 C C   . SER C 3 334 ? 140.352 125.017 116.088 1.00 32.99 ? 316 SER C C   1 
ATOM   6048 O O   . SER C 3 334 ? 140.249 124.163 115.206 1.00 39.53 ? 316 SER C O   1 
ATOM   6049 C CB  . SER C 3 334 ? 138.585 125.178 117.812 1.00 35.90 ? 316 SER C CB  1 
ATOM   6050 O OG  . SER C 3 334 ? 137.935 124.361 118.765 1.00 43.40 ? 316 SER C OG  1 
ATOM   6051 N N   . CYS C 3 335 ? 140.770 126.257 115.844 1.00 29.42 ? 317 CYS C N   1 
ATOM   6052 C CA  . CYS C 3 335 ? 141.047 126.755 114.506 1.00 21.42 ? 317 CYS C CA  1 
ATOM   6053 C C   . CYS C 3 335 ? 142.388 127.467 114.512 1.00 24.33 ? 317 CYS C C   1 
ATOM   6054 O O   . CYS C 3 335 ? 142.827 127.973 115.548 1.00 36.71 ? 317 CYS C O   1 
ATOM   6055 C CB  . CYS C 3 335 ? 139.949 127.706 114.040 1.00 27.42 ? 317 CYS C CB  1 
ATOM   6056 S SG  . CYS C 3 335 ? 139.580 129.008 115.230 1.00 51.78 ? 317 CYS C SG  1 
ATOM   6057 N N   . LEU C 3 336 ? 143.034 127.501 113.352 1.00 19.36 ? 318 LEU C N   1 
ATOM   6058 C CA  . LEU C 3 336 ? 144.357 128.084 113.217 1.00 14.41 ? 318 LEU C CA  1 
ATOM   6059 C C   . LEU C 3 336 ? 144.524 128.572 111.787 1.00 31.03 ? 318 LEU C C   1 
ATOM   6060 O O   . LEU C 3 336 ? 144.078 127.921 110.839 1.00 46.07 ? 318 LEU C O   1 
ATOM   6061 C CB  . LEU C 3 336 ? 145.439 127.058 113.593 1.00 12.01 ? 318 LEU C CB  1 
ATOM   6062 C CG  . LEU C 3 336 ? 146.920 127.445 113.530 1.00 14.60 ? 318 LEU C CG  1 
ATOM   6063 C CD1 . LEU C 3 336 ? 147.692 126.621 114.542 1.00 28.66 ? 318 LEU C CD1 1 
ATOM   6064 C CD2 . LEU C 3 336 ? 147.521 127.249 112.150 1.00 17.21 ? 318 LEU C CD2 1 
ATOM   6065 N N   . GLY C 3 337 ? 145.158 129.726 111.640 1.00 13.30 ? 319 GLY C N   1 
ATOM   6066 C CA  . GLY C 3 337 ? 145.373 130.307 110.326 1.00 18.99 ? 319 GLY C CA  1 
ATOM   6067 C C   . GLY C 3 337 ? 146.617 131.162 110.307 1.00 17.48 ? 319 GLY C C   1 
ATOM   6068 O O   . GLY C 3 337 ? 146.961 131.813 111.297 1.00 26.98 ? 319 GLY C O   1 
ATOM   6069 N N   . VAL C 3 338 ? 147.291 131.164 109.159 1.00 21.78 ? 320 VAL C N   1 
ATOM   6070 C CA  . VAL C 3 338 ? 148.508 131.935 108.938 1.00 18.33 ? 320 VAL C CA  1 
ATOM   6071 C C   . VAL C 3 338 ? 148.179 133.065 107.978 1.00 21.75 ? 320 VAL C C   1 
ATOM   6072 O O   . VAL C 3 338 ? 147.460 132.864 106.993 1.00 41.10 ? 320 VAL C O   1 
ATOM   6073 C CB  . VAL C 3 338 ? 149.649 131.063 108.375 1.00 19.91 ? 320 VAL C CB  1 
ATOM   6074 C CG1 . VAL C 3 338 ? 150.892 131.905 108.138 1.00 16.37 ? 320 VAL C CG1 1 
ATOM   6075 C CG2 . VAL C 3 338 ? 149.951 129.910 109.314 1.00 26.71 ? 320 VAL C CG2 1 
ATOM   6076 N N   . THR C 3 339 ? 148.701 134.251 108.270 1.00 12.69 ? 321 THR C N   1 
ATOM   6077 C CA  . THR C 3 339 ? 148.429 135.414 107.441 1.00 11.20 ? 321 THR C CA  1 
ATOM   6078 C C   . THR C 3 339 ? 148.979 135.199 106.036 1.00 19.15 ? 321 THR C C   1 
ATOM   6079 O O   . THR C 3 339 ? 149.943 134.458 105.830 1.00 28.92 ? 321 THR C O   1 
ATOM   6080 C CB  . THR C 3 339 ? 149.048 136.663 108.065 1.00 25.61 ? 321 THR C CB  1 
ATOM   6081 O OG1 . THR C 3 339 ? 148.722 136.714 109.459 1.00 32.08 ? 321 THR C OG1 1 
ATOM   6082 C CG2 . THR C 3 339 ? 148.524 137.910 107.396 1.00 28.80 ? 321 THR C CG2 1 
ATOM   6083 N N   . ASP C 3 340 ? 148.338 135.845 105.058 1.00 24.42 ? 322 ASP C N   1 
ATOM   6084 C CA  . ASP C 3 340 ? 148.725 135.647 103.665 1.00 31.68 ? 322 ASP C CA  1 
ATOM   6085 C C   . ASP C 3 340 ? 150.158 136.099 103.417 1.00 34.68 ? 322 ASP C C   1 
ATOM   6086 O O   . ASP C 3 340 ? 150.930 135.399 102.751 1.00 35.24 ? 322 ASP C O   1 
ATOM   6087 C CB  . ASP C 3 340 ? 147.765 136.392 102.741 1.00 29.76 ? 322 ASP C CB  1 
ATOM   6088 C CG  . ASP C 3 340 ? 147.533 135.661 101.437 1.00 34.00 ? 322 ASP C CG  1 
ATOM   6089 O OD1 . ASP C 3 340 ? 148.340 135.840 100.503 1.00 29.41 ? 322 ASP C OD1 1 
ATOM   6090 O OD2 . ASP C 3 340 ? 146.544 134.904 101.349 1.00 34.78 ? 322 ASP C OD2 1 
ATOM   6091 N N   . ASP C 3 341 ? 150.535 137.262 103.944 1.00 27.73 ? 323 ASP C N   1 
ATOM   6092 C CA  . ASP C 3 341 ? 151.918 137.720 103.850 1.00 26.16 ? 323 ASP C CA  1 
ATOM   6093 C C   . ASP C 3 341 ? 152.847 137.003 104.823 1.00 34.67 ? 323 ASP C C   1 
ATOM   6094 O O   . ASP C 3 341 ? 154.066 137.172 104.724 1.00 39.46 ? 323 ASP C O   1 
ATOM   6095 C CB  . ASP C 3 341 ? 152.009 139.238 104.076 1.00 31.19 ? 323 ASP C CB  1 
ATOM   6096 C CG  . ASP C 3 341 ? 151.333 139.697 105.360 1.00 30.41 ? 323 ASP C CG  1 
ATOM   6097 O OD1 . ASP C 3 341 ? 151.443 139.004 106.391 1.00 26.50 ? 323 ASP C OD1 1 
ATOM   6098 O OD2 . ASP C 3 341 ? 150.690 140.767 105.335 1.00 33.69 ? 323 ASP C OD2 1 
ATOM   6099 N N   . GLY C 3 342 ? 152.311 136.212 105.751 1.00 31.90 ? 324 GLY C N   1 
ATOM   6100 C CA  . GLY C 3 342 ? 153.141 135.498 106.699 1.00 22.05 ? 324 GLY C CA  1 
ATOM   6101 C C   . GLY C 3 342 ? 153.603 136.319 107.878 1.00 25.72 ? 324 GLY C C   1 
ATOM   6102 O O   . GLY C 3 342 ? 154.511 135.893 108.597 1.00 29.99 ? 324 GLY C O   1 
ATOM   6103 N N   . MET C 3 343 ? 153.002 137.486 108.109 1.00 27.26 ? 325 MET C N   1 
ATOM   6104 C CA  . MET C 3 343 ? 153.431 138.351 109.201 1.00 32.03 ? 325 MET C CA  1 
ATOM   6105 C C   . MET C 3 343 ? 153.036 137.814 110.569 1.00 34.53 ? 325 MET C C   1 
ATOM   6106 O O   . MET C 3 343 ? 153.731 138.085 111.553 1.00 34.17 ? 325 MET C O   1 
ATOM   6107 C CB  . MET C 3 343 ? 152.843 139.759 109.036 1.00 33.28 ? 325 MET C CB  1 
ATOM   6108 C CG  . MET C 3 343 ? 153.567 140.709 108.071 1.00 36.90 ? 325 MET C CG  1 
ATOM   6109 S SD  . MET C 3 343 ? 155.358 140.857 108.252 1.00 35.05 ? 325 MET C SD  1 
ATOM   6110 C CE  . MET C 3 343 ? 155.863 140.913 106.536 1.00 29.78 ? 325 MET C CE  1 
ATOM   6111 N N   . ALA C 3 344 ? 151.938 137.065 110.665 1.00 27.59 ? 326 ALA C N   1 
ATOM   6112 C CA  . ALA C 3 344 ? 151.390 136.683 111.957 1.00 24.69 ? 326 ALA C CA  1 
ATOM   6113 C C   . ALA C 3 344 ? 150.613 135.381 111.840 1.00 15.07 ? 326 ALA C C   1 
ATOM   6114 O O   . ALA C 3 344 ? 150.276 134.922 110.747 1.00 33.19 ? 326 ALA C O   1 
ATOM   6115 C CB  . ALA C 3 344 ? 150.487 137.783 112.524 1.00 35.58 ? 326 ALA C CB  1 
ATOM   6116 N N   . VAL C 3 345 ? 150.336 134.796 113.003 1.00 18.22 ? 327 VAL C N   1 
ATOM   6117 C CA  . VAL C 3 345 ? 149.586 133.552 113.138 1.00 19.40 ? 327 VAL C CA  1 
ATOM   6118 C C   . VAL C 3 345 ? 148.459 133.805 114.125 1.00 24.21 ? 327 VAL C C   1 
ATOM   6119 O O   . VAL C 3 345 ? 148.688 134.394 115.184 1.00 50.04 ? 327 VAL C O   1 
ATOM   6120 C CB  . VAL C 3 345 ? 150.478 132.399 113.640 1.00 21.68 ? 327 VAL C CB  1 
ATOM   6121 C CG1 . VAL C 3 345 ? 149.630 131.205 114.064 1.00 18.58 ? 327 VAL C CG1 1 
ATOM   6122 C CG2 . VAL C 3 345 ? 151.493 132.010 112.585 1.00 24.70 ? 327 VAL C CG2 1 
ATOM   6123 N N   . ALA C 3 346 ? 147.254 133.355 113.792 1.00 9.67  ? 328 ALA C N   1 
ATOM   6124 C CA  . ALA C 3 346 ? 146.082 133.532 114.640 1.00 17.08 ? 328 ALA C CA  1 
ATOM   6125 C C   . ALA C 3 346 ? 145.450 132.179 114.925 1.00 21.55 ? 328 ALA C C   1 
ATOM   6126 O O   . ALA C 3 346 ? 145.231 131.387 114.004 1.00 39.56 ? 328 ALA C O   1 
ATOM   6127 C CB  . ALA C 3 346 ? 145.068 134.465 113.979 1.00 25.50 ? 328 ALA C CB  1 
ATOM   6128 N N   . THR C 3 347 ? 145.161 131.923 116.200 1.00 17.35 ? 329 THR C N   1 
ATOM   6129 C CA  . THR C 3 347 ? 144.574 130.668 116.652 1.00 27.00 ? 329 THR C CA  1 
ATOM   6130 C C   . THR C 3 347 ? 143.384 130.971 117.545 1.00 26.86 ? 329 THR C C   1 
ATOM   6131 O O   . THR C 3 347 ? 143.471 131.837 118.420 1.00 38.37 ? 329 THR C O   1 
ATOM   6132 C CB  . THR C 3 347 ? 145.591 129.820 117.422 1.00 26.45 ? 329 THR C CB  1 
ATOM   6133 O OG1 . THR C 3 347 ? 145.809 130.393 118.716 1.00 26.39 ? 329 THR C OG1 1 
ATOM   6134 C CG2 . THR C 3 347 ? 146.912 129.756 116.678 1.00 28.93 ? 329 THR C CG2 1 
ATOM   6135 N N   . GLY C 3 348 ? 142.281 130.258 117.322 1.00 18.07 ? 330 GLY C N   1 
ATOM   6136 C CA  . GLY C 3 348 ? 141.104 130.362 118.163 1.00 24.88 ? 330 GLY C CA  1 
ATOM   6137 C C   . GLY C 3 348 ? 140.915 129.115 118.995 1.00 32.86 ? 330 GLY C C   1 
ATOM   6138 O O   . GLY C 3 348 ? 141.323 128.027 118.580 1.00 45.08 ? 330 GLY C O   1 
ATOM   6139 N N   . SER C 3 349 ? 140.299 129.253 120.165 1.00 39.15 ? 331 SER C N   1 
ATOM   6140 C CA  . SER C 3 349 ? 140.156 128.146 121.101 1.00 46.03 ? 331 SER C CA  1 
ATOM   6141 C C   . SER C 3 349 ? 138.767 128.212 121.722 1.00 49.72 ? 331 SER C C   1 
ATOM   6142 O O   . SER C 3 349 ? 138.014 129.166 121.509 1.00 50.96 ? 331 SER C O   1 
ATOM   6143 C CB  . SER C 3 349 ? 141.263 128.193 122.161 1.00 48.46 ? 331 SER C CB  1 
ATOM   6144 O OG  . SER C 3 349 ? 141.495 129.523 122.587 1.00 50.25 ? 331 SER C OG  1 
ATOM   6145 N N   . TRP C 3 350 ? 138.436 127.191 122.504 1.00 53.42 ? 332 TRP C N   1 
ATOM   6146 C CA  . TRP C 3 350 ? 137.141 127.073 123.154 1.00 50.03 ? 332 TRP C CA  1 
ATOM   6147 C C   . TRP C 3 350 ? 137.020 127.945 124.398 1.00 53.38 ? 332 TRP C C   1 
ATOM   6148 O O   . TRP C 3 350 ? 135.955 127.961 125.024 1.00 56.36 ? 332 TRP C O   1 
ATOM   6149 C CB  . TRP C 3 350 ? 136.887 125.606 123.521 1.00 50.39 ? 332 TRP C CB  1 
ATOM   6150 C CG  . TRP C 3 350 ? 136.339 124.745 122.409 1.00 52.53 ? 332 TRP C CG  1 
ATOM   6151 C CD1 . TRP C 3 350 ? 136.176 125.084 121.096 1.00 51.78 ? 332 TRP C CD1 1 
ATOM   6152 C CD2 . TRP C 3 350 ? 135.907 123.387 122.524 1.00 57.39 ? 332 TRP C CD2 1 
ATOM   6153 N NE1 . TRP C 3 350 ? 135.652 124.029 120.394 1.00 54.21 ? 332 TRP C NE1 1 
ATOM   6154 C CE2 . TRP C 3 350 ? 135.479 122.974 121.248 1.00 54.62 ? 332 TRP C CE2 1 
ATOM   6155 C CE3 . TRP C 3 350 ? 135.835 122.482 123.585 1.00 56.80 ? 332 TRP C CE3 1 
ATOM   6156 C CZ2 . TRP C 3 350 ? 134.990 121.695 121.006 1.00 53.70 ? 332 TRP C CZ2 1 
ATOM   6157 C CZ3 . TRP C 3 350 ? 135.356 121.215 123.340 1.00 54.21 ? 332 TRP C CZ3 1 
ATOM   6158 C CH2 . TRP C 3 350 ? 134.934 120.833 122.065 1.00 56.09 ? 332 TRP C CH2 1 
ATOM   6159 N N   . ASP C 3 351 ? 138.076 128.671 124.770 1.00 49.16 ? 333 ASP C N   1 
ATOM   6160 C CA  . ASP C 3 351 ? 138.040 129.589 125.900 1.00 50.52 ? 333 ASP C CA  1 
ATOM   6161 C C   . ASP C 3 351 ? 137.553 130.981 125.508 1.00 51.84 ? 333 ASP C C   1 
ATOM   6162 O O   . ASP C 3 351 ? 137.712 131.925 126.289 1.00 52.53 ? 333 ASP C O   1 
ATOM   6163 C CB  . ASP C 3 351 ? 139.421 129.684 126.545 1.00 54.07 ? 333 ASP C CB  1 
ATOM   6164 C CG  . ASP C 3 351 ? 140.474 130.222 125.599 1.00 52.10 ? 333 ASP C CG  1 
ATOM   6165 O OD1 . ASP C 3 351 ? 140.245 130.180 124.374 1.00 51.53 ? 333 ASP C OD1 1 
ATOM   6166 O OD2 . ASP C 3 351 ? 141.530 130.687 126.077 1.00 52.57 ? 333 ASP C OD2 1 
ATOM   6167 N N   . SER C 3 352 ? 136.969 131.132 124.318 1.00 48.55 ? 334 SER C N   1 
ATOM   6168 C CA  . SER C 3 352 ? 136.354 132.374 123.859 1.00 46.97 ? 334 SER C CA  1 
ATOM   6169 C C   . SER C 3 352 ? 137.366 133.482 123.585 1.00 49.22 ? 334 SER C C   1 
ATOM   6170 O O   . SER C 3 352 ? 136.975 134.646 123.449 1.00 53.46 ? 334 SER C O   1 
ATOM   6171 C CB  . SER C 3 352 ? 135.301 132.874 124.856 1.00 48.61 ? 334 SER C CB  1 
ATOM   6172 O OG  . SER C 3 352 ? 135.890 133.339 126.058 1.00 53.65 ? 334 SER C OG  1 
ATOM   6173 N N   . PHE C 3 353 ? 138.658 133.159 123.508 1.00 45.48 ? 335 PHE C N   1 
ATOM   6174 C CA  . PHE C 3 353 ? 139.696 134.111 123.138 1.00 44.53 ? 335 PHE C CA  1 
ATOM   6175 C C   . PHE C 3 353 ? 140.550 133.517 122.028 1.00 36.62 ? 335 PHE C C   1 
ATOM   6176 O O   . PHE C 3 353 ? 141.046 132.393 122.153 1.00 42.86 ? 335 PHE C O   1 
ATOM   6177 C CB  . PHE C 3 353 ? 140.594 134.467 124.330 1.00 42.72 ? 335 PHE C CB  1 
ATOM   6178 C CG  . PHE C 3 353 ? 139.859 134.588 125.631 1.00 44.01 ? 335 PHE C CG  1 
ATOM   6179 C CD1 . PHE C 3 353 ? 138.880 135.548 125.803 1.00 42.72 ? 335 PHE C CD1 1 
ATOM   6180 C CD2 . PHE C 3 353 ? 140.155 133.745 126.687 1.00 46.67 ? 335 PHE C CD2 1 
ATOM   6181 C CE1 . PHE C 3 353 ? 138.204 135.660 127.001 1.00 44.31 ? 335 PHE C CE1 1 
ATOM   6182 C CE2 . PHE C 3 353 ? 139.484 133.852 127.887 1.00 49.60 ? 335 PHE C CE2 1 
ATOM   6183 C CZ  . PHE C 3 353 ? 138.507 134.812 128.045 1.00 48.36 ? 335 PHE C CZ  1 
ATOM   6184 N N   . LEU C 3 354 ? 140.717 134.276 120.947 1.00 29.96 ? 336 LEU C N   1 
ATOM   6185 C CA  . LEU C 3 354 ? 141.614 133.921 119.857 1.00 31.53 ? 336 LEU C CA  1 
ATOM   6186 C C   . LEU C 3 354 ? 142.737 134.945 119.803 1.00 27.02 ? 336 LEU C C   1 
ATOM   6187 O O   . LEU C 3 354 ? 142.485 136.148 119.696 1.00 38.59 ? 336 LEU C O   1 
ATOM   6188 C CB  . LEU C 3 354 ? 140.861 133.844 118.515 1.00 33.06 ? 336 LEU C CB  1 
ATOM   6189 C CG  . LEU C 3 354 ? 140.461 135.102 117.738 1.00 27.55 ? 336 LEU C CG  1 
ATOM   6190 C CD1 . LEU C 3 354 ? 141.521 135.490 116.718 1.00 31.80 ? 336 LEU C CD1 1 
ATOM   6191 C CD2 . LEU C 3 354 ? 139.127 134.889 117.048 1.00 18.72 ? 336 LEU C CD2 1 
ATOM   6192 N N   . LYS C 3 355 ? 143.973 134.459 119.875 1.00 17.79 ? 337 LYS C N   1 
ATOM   6193 C CA  . LYS C 3 355 ? 145.146 135.302 120.044 1.00 27.68 ? 337 LYS C CA  1 
ATOM   6194 C C   . LYS C 3 355 ? 146.017 135.238 118.800 1.00 24.53 ? 337 LYS C C   1 
ATOM   6195 O O   . LYS C 3 355 ? 146.105 134.207 118.129 1.00 41.74 ? 337 LYS C O   1 
ATOM   6196 C CB  . LYS C 3 355 ? 145.964 134.879 121.271 1.00 40.49 ? 337 LYS C CB  1 
ATOM   6197 C CG  . LYS C 3 355 ? 145.127 134.649 122.521 1.00 42.78 ? 337 LYS C CG  1 
ATOM   6198 C CD  . LYS C 3 355 ? 145.969 134.709 123.791 1.00 30.33 ? 337 LYS C CD  1 
ATOM   6199 C CE  . LYS C 3 355 ? 146.834 133.482 123.991 1.00 33.77 ? 337 LYS C CE  1 
ATOM   6200 N NZ  . LYS C 3 355 ? 146.762 133.022 125.401 1.00 37.54 ? 337 LYS C NZ  1 
ATOM   6201 N N   . ILE C 3 356 ? 146.674 136.358 118.511 1.00 23.00 ? 338 ILE C N   1 
ATOM   6202 C CA  . ILE C 3 356 ? 147.559 136.496 117.362 1.00 24.12 ? 338 ILE C CA  1 
ATOM   6203 C C   . ILE C 3 356 ? 148.992 136.357 117.852 1.00 24.39 ? 338 ILE C C   1 
ATOM   6204 O O   . ILE C 3 356 ? 149.361 136.944 118.875 1.00 47.57 ? 338 ILE C O   1 
ATOM   6205 C CB  . ILE C 3 356 ? 147.355 137.839 116.636 1.00 28.67 ? 338 ILE C CB  1 
ATOM   6206 C CG1 . ILE C 3 356 ? 145.955 137.896 116.014 1.00 23.62 ? 338 ILE C CG1 1 
ATOM   6207 C CG2 . ILE C 3 356 ? 148.443 138.029 115.579 1.00 27.52 ? 338 ILE C CG2 1 
ATOM   6208 C CD1 . ILE C 3 356 ? 145.544 139.267 115.517 1.00 33.60 ? 338 ILE C CD1 1 
ATOM   6209 N N   . TRP C 3 357 ? 149.792 135.585 117.121 1.00 8.71  ? 339 TRP C N   1 
ATOM   6210 C CA  . TRP C 3 357 ? 151.174 135.286 117.467 1.00 17.56 ? 339 TRP C CA  1 
ATOM   6211 C C   . TRP C 3 357 ? 152.075 135.783 116.349 1.00 21.68 ? 339 TRP C C   1 
ATOM   6212 O O   . TRP C 3 357 ? 151.631 135.920 115.206 1.00 33.45 ? 339 TRP C O   1 
ATOM   6213 C CB  . TRP C 3 357 ? 151.393 133.782 117.687 1.00 24.84 ? 339 TRP C CB  1 
ATOM   6214 C CG  . TRP C 3 357 ? 150.300 133.078 118.451 1.00 25.84 ? 339 TRP C CG  1 
ATOM   6215 C CD1 . TRP C 3 357 ? 149.064 132.721 117.990 1.00 31.12 ? 339 TRP C CD1 1 
ATOM   6216 C CD2 . TRP C 3 357 ? 150.361 132.633 119.811 1.00 29.78 ? 339 TRP C CD2 1 
ATOM   6217 N NE1 . TRP C 3 357 ? 148.352 132.093 118.980 1.00 35.34 ? 339 TRP C NE1 1 
ATOM   6218 C CE2 . TRP C 3 357 ? 149.126 132.025 120.108 1.00 30.01 ? 339 TRP C CE2 1 
ATOM   6219 C CE3 . TRP C 3 357 ? 151.338 132.694 120.806 1.00 32.53 ? 339 TRP C CE3 1 
ATOM   6220 C CZ2 . TRP C 3 357 ? 148.844 131.483 121.356 1.00 30.86 ? 339 TRP C CZ2 1 
ATOM   6221 C CZ3 . TRP C 3 357 ? 151.056 132.155 122.044 1.00 35.36 ? 339 TRP C CZ3 1 
ATOM   6222 C CH2 . TRP C 3 357 ? 149.819 131.558 122.309 1.00 33.14 ? 339 TRP C CH2 1 
ATOM   6223 N N   . ASN C 3 358 ? 153.331 136.061 116.681 1.00 31.33 ? 340 ASN C N   1 
ATOM   6224 C CA  . ASN C 3 358 ? 154.287 136.563 115.703 1.00 30.99 ? 340 ASN C CA  1 
ATOM   6225 C C   . ASN C 3 358 ? 155.714 136.264 116.143 1.00 35.28 ? 340 ASN C C   1 
ATOM   6226 O O   . ASN C 3 358 ? 156.601 136.050 115.319 1.00 33.48 ? 340 ASN C O   1 
ATOM   6227 C CB  . ASN C 3 358 ? 154.103 138.067 115.504 1.00 39.05 ? 340 ASN C CB  1 
ATOM   6228 C CG  . ASN C 3 358 ? 154.802 138.583 114.265 1.00 40.49 ? 340 ASN C CG  1 
ATOM   6229 O OD1 . ASN C 3 358 ? 155.572 137.868 113.626 1.00 40.96 ? 340 ASN C OD1 1 
ATOM   6230 N ND2 . ASN C 3 358 ? 154.529 139.833 113.912 1.00 36.31 ? 340 ASN C ND2 1 
ATOM   6231 O OXT . ASN C 3 358 ? 156.014 136.230 117.335 1.00 41.64 ? 340 ASN C OXT 1 
ATOM   6232 N N   . ILE D 4 9   ? 124.383 96.742  95.446  1.00 70.66 ? 9   ILE D N   1 
ATOM   6233 C CA  . ILE D 4 9   ? 124.328 95.560  94.596  1.00 70.68 ? 9   ILE D CA  1 
ATOM   6234 C C   . ILE D 4 9   ? 125.273 95.750  93.415  1.00 69.78 ? 9   ILE D C   1 
ATOM   6235 O O   . ILE D 4 9   ? 126.214 94.978  93.231  1.00 67.15 ? 9   ILE D O   1 
ATOM   6236 C CB  . ILE D 4 9   ? 122.884 95.276  94.119  1.00 69.59 ? 9   ILE D CB  1 
ATOM   6237 C CG1 . ILE D 4 9   ? 121.990 94.885  95.303  1.00 67.92 ? 9   ILE D CG1 1 
ATOM   6238 C CG2 . ILE D 4 9   ? 122.878 94.172  93.062  1.00 66.74 ? 9   ILE D CG2 1 
ATOM   6239 C CD1 . ILE D 4 9   ? 120.502 95.036  95.033  1.00 67.86 ? 9   ILE D CD1 1 
ATOM   6240 N N   . ALA D 4 10  ? 125.014 96.787  92.619  1.00 73.24 ? 10  ALA D N   1 
ATOM   6241 C CA  . ALA D 4 10  ? 125.807 97.098  91.437  1.00 72.30 ? 10  ALA D CA  1 
ATOM   6242 C C   . ALA D 4 10  ? 126.902 98.126  91.699  1.00 73.35 ? 10  ALA D C   1 
ATOM   6243 O O   . ALA D 4 10  ? 127.575 98.545  90.752  1.00 73.96 ? 10  ALA D O   1 
ATOM   6244 C CB  . ALA D 4 10  ? 124.894 97.601  90.314  1.00 69.80 ? 10  ALA D CB  1 
ATOM   6245 N N   . GLN D 4 11  ? 127.099 98.545  92.952  1.00 74.55 ? 11  GLN D N   1 
ATOM   6246 C CA  . GLN D 4 11  ? 128.101 99.562  93.252  1.00 75.99 ? 11  GLN D CA  1 
ATOM   6247 C C   . GLN D 4 11  ? 129.524 99.064  93.022  1.00 75.69 ? 11  GLN D C   1 
ATOM   6248 O O   . GLN D 4 11  ? 130.439 99.884  92.873  1.00 71.97 ? 11  GLN D O   1 
ATOM   6249 C CB  . GLN D 4 11  ? 127.944 100.032 94.700  1.00 75.78 ? 11  GLN D CB  1 
ATOM   6250 C CG  . GLN D 4 11  ? 126.737 100.932 94.937  1.00 75.22 ? 11  GLN D CG  1 
ATOM   6251 C CD  . GLN D 4 11  ? 125.451 100.150 95.145  1.00 75.82 ? 11  GLN D CD  1 
ATOM   6252 O OE1 . GLN D 4 11  ? 125.404 98.938  94.934  1.00 74.78 ? 11  GLN D OE1 1 
ATOM   6253 N NE2 . GLN D 4 11  ? 124.398 100.845 95.560  1.00 77.96 ? 11  GLN D NE2 1 
ATOM   6254 N N   . ALA D 4 12  ? 129.732 97.745  93.005  1.00 73.72 ? 12  ALA D N   1 
ATOM   6255 C CA  . ALA D 4 12  ? 131.070 97.208  92.782  1.00 72.27 ? 12  ALA D CA  1 
ATOM   6256 C C   . ALA D 4 12  ? 131.597 97.573  91.402  1.00 71.54 ? 12  ALA D C   1 
ATOM   6257 O O   . ALA D 4 12  ? 132.796 97.831  91.246  1.00 68.77 ? 12  ALA D O   1 
ATOM   6258 C CB  . ALA D 4 12  ? 131.061 95.690  92.962  1.00 71.85 ? 12  ALA D CB  1 
ATOM   6259 N N   . ARG D 4 13  ? 130.725 97.588  90.391  1.00 70.62 ? 13  ARG D N   1 
ATOM   6260 C CA  . ARG D 4 13  ? 131.150 97.980  89.050  1.00 69.03 ? 13  ARG D CA  1 
ATOM   6261 C C   . ARG D 4 13  ? 131.642 99.422  89.038  1.00 68.80 ? 13  ARG D C   1 
ATOM   6262 O O   . ARG D 4 13  ? 132.684 99.732  88.449  1.00 66.90 ? 13  ARG D O   1 
ATOM   6263 C CB  . ARG D 4 13  ? 129.998 97.796  88.063  1.00 67.19 ? 13  ARG D CB  1 
ATOM   6264 N N   . LYS D 4 14  ? 130.907 100.319 89.698  1.00 73.07 ? 14  LYS D N   1 
ATOM   6265 C CA  . LYS D 4 14  ? 131.336 101.711 89.780  1.00 75.07 ? 14  LYS D CA  1 
ATOM   6266 C C   . LYS D 4 14  ? 132.657 101.836 90.529  1.00 76.39 ? 14  LYS D C   1 
ATOM   6267 O O   . LYS D 4 14  ? 133.548 102.589 90.115  1.00 76.22 ? 14  LYS D O   1 
ATOM   6268 C CB  . LYS D 4 14  ? 130.245 102.545 90.455  1.00 76.95 ? 14  LYS D CB  1 
ATOM   6269 C CG  . LYS D 4 14  ? 130.489 104.048 90.430  1.00 78.49 ? 14  LYS D CG  1 
ATOM   6270 C CD  . LYS D 4 14  ? 129.238 104.847 90.810  1.00 77.95 ? 14  LYS D CD  1 
ATOM   6271 C CE  . LYS D 4 14  ? 128.770 104.593 92.242  1.00 76.93 ? 14  LYS D CE  1 
ATOM   6272 N NZ  . LYS D 4 14  ? 129.784 105.000 93.254  1.00 79.57 ? 14  LYS D NZ  1 
ATOM   6273 N N   . LEU D 4 15  ? 132.806 101.093 91.629  1.00 74.51 ? 15  LEU D N   1 
ATOM   6274 C CA  . LEU D 4 15  ? 134.033 101.169 92.419  1.00 73.10 ? 15  LEU D CA  1 
ATOM   6275 C C   . LEU D 4 15  ? 135.240 100.700 91.614  1.00 72.11 ? 15  LEU D C   1 
ATOM   6276 O O   . LEU D 4 15  ? 136.285 101.365 91.590  1.00 67.35 ? 15  LEU D O   1 
ATOM   6277 C CB  . LEU D 4 15  ? 133.879 100.336 93.693  1.00 74.02 ? 15  LEU D CB  1 
ATOM   6278 C CG  . LEU D 4 15  ? 134.995 100.470 94.732  1.00 72.33 ? 15  LEU D CG  1 
ATOM   6279 C CD1 . LEU D 4 15  ? 134.404 100.564 96.131  1.00 72.07 ? 15  LEU D CD1 1 
ATOM   6280 C CD2 . LEU D 4 15  ? 135.972 99.306  94.645  1.00 71.31 ? 15  LEU D CD2 1 
ATOM   6281 N N   . VAL D 4 16  ? 135.118 99.550  90.945  1.00 69.51 ? 16  VAL D N   1 
ATOM   6282 C CA  . VAL D 4 16  ? 136.248 99.032  90.181  1.00 67.26 ? 16  VAL D CA  1 
ATOM   6283 C C   . VAL D 4 16  ? 136.526 99.914  88.971  1.00 66.19 ? 16  VAL D C   1 
ATOM   6284 O O   . VAL D 4 16  ? 137.685 100.074 88.573  1.00 64.53 ? 16  VAL D O   1 
ATOM   6285 C CB  . VAL D 4 16  ? 136.021 97.559  89.780  1.00 72.06 ? 16  VAL D CB  1 
ATOM   6286 C CG1 . VAL D 4 16  ? 134.882 97.411  88.782  1.00 71.59 ? 16  VAL D CG1 1 
ATOM   6287 C CG2 . VAL D 4 16  ? 137.304 96.955  89.220  1.00 70.08 ? 16  VAL D CG2 1 
ATOM   6288 N N   . GLU D 4 17  ? 135.489 100.498 88.361  1.00 63.78 ? 17  GLU D N   1 
ATOM   6289 C CA  . GLU D 4 17  ? 135.720 101.428 87.260  1.00 64.23 ? 17  GLU D CA  1 
ATOM   6290 C C   . GLU D 4 17  ? 136.499 102.650 87.728  1.00 63.72 ? 17  GLU D C   1 
ATOM   6291 O O   . GLU D 4 17  ? 137.423 103.106 87.045  1.00 62.26 ? 17  GLU D O   1 
ATOM   6292 C CB  . GLU D 4 17  ? 134.387 101.848 86.642  1.00 61.88 ? 17  GLU D CB  1 
ATOM   6293 N N   . GLN D 4 18  ? 136.143 103.192 88.896  1.00 61.87 ? 18  GLN D N   1 
ATOM   6294 C CA  . GLN D 4 18  ? 136.881 104.333 89.432  1.00 61.97 ? 18  GLN D CA  1 
ATOM   6295 C C   . GLN D 4 18  ? 138.326 103.957 89.740  1.00 62.49 ? 18  GLN D C   1 
ATOM   6296 O O   . GLN D 4 18  ? 139.251 104.732 89.464  1.00 56.16 ? 18  GLN D O   1 
ATOM   6297 C CB  . GLN D 4 18  ? 136.186 104.863 90.687  1.00 64.64 ? 18  GLN D CB  1 
ATOM   6298 C CG  . GLN D 4 18  ? 136.394 106.352 90.940  1.00 64.40 ? 18  GLN D CG  1 
ATOM   6299 C CD  . GLN D 4 18  ? 137.787 106.677 91.443  1.00 62.99 ? 18  GLN D CD  1 
ATOM   6300 O OE1 . GLN D 4 18  ? 138.364 105.933 92.236  1.00 62.48 ? 18  GLN D OE1 1 
ATOM   6301 N NE2 . GLN D 4 18  ? 138.337 107.792 90.980  1.00 57.80 ? 18  GLN D NE2 1 
ATOM   6302 N N   . LEU D 4 19  ? 138.538 102.773 90.321  1.00 69.98 ? 19  LEU D N   1 
ATOM   6303 C CA  . LEU D 4 19  ? 139.899 102.339 90.622  1.00 67.82 ? 19  LEU D CA  1 
ATOM   6304 C C   . LEU D 4 19  ? 140.715 102.161 89.346  1.00 66.64 ? 19  LEU D C   1 
ATOM   6305 O O   . LEU D 4 19  ? 141.892 102.532 89.297  1.00 59.22 ? 19  LEU D O   1 
ATOM   6306 C CB  . LEU D 4 19  ? 139.869 101.042 91.431  1.00 72.68 ? 19  LEU D CB  1 
ATOM   6307 C CG  . LEU D 4 19  ? 141.177 100.618 92.108  1.00 68.83 ? 19  LEU D CG  1 
ATOM   6308 C CD1 . LEU D 4 19  ? 141.582 101.600 93.197  1.00 64.33 ? 19  LEU D CD1 1 
ATOM   6309 C CD2 . LEU D 4 19  ? 141.050 99.215  92.685  1.00 71.07 ? 19  LEU D CD2 1 
ATOM   6310 N N   . LYS D 4 20  ? 140.105 101.597 88.300  1.00 71.89 ? 20  LYS D N   1 
ATOM   6311 C CA  . LYS D 4 20  ? 140.792 101.467 87.019  1.00 65.95 ? 20  LYS D CA  1 
ATOM   6312 C C   . LYS D 4 20  ? 141.131 102.832 86.435  1.00 65.39 ? 20  LYS D C   1 
ATOM   6313 O O   . LYS D 4 20  ? 142.219 103.026 85.882  1.00 62.82 ? 20  LYS D O   1 
ATOM   6314 C CB  . LYS D 4 20  ? 139.926 100.669 86.042  1.00 65.90 ? 20  LYS D CB  1 
ATOM   6315 C CG  . LYS D 4 20  ? 139.930 99.157  86.304  1.00 65.44 ? 20  LYS D CG  1 
ATOM   6316 C CD  . LYS D 4 20  ? 139.273 98.307  85.201  1.00 68.76 ? 20  LYS D CD  1 
ATOM   6317 C CE  . LYS D 4 20  ? 139.854 98.524  83.806  1.00 69.35 ? 20  LYS D CE  1 
ATOM   6318 N NZ  . LYS D 4 20  ? 141.339 98.411  83.788  1.00 68.54 ? 20  LYS D NZ  1 
ATOM   6319 N N   . MET D 4 21  ? 140.205 103.789 86.542  1.00 66.27 ? 21  MET D N   1 
ATOM   6320 C CA  . MET D 4 21  ? 140.463 105.128 86.022  1.00 63.93 ? 21  MET D CA  1 
ATOM   6321 C C   . MET D 4 21  ? 141.619 105.792 86.759  1.00 62.48 ? 21  MET D C   1 
ATOM   6322 O O   . MET D 4 21  ? 142.453 106.465 86.143  1.00 58.63 ? 21  MET D O   1 
ATOM   6323 C CB  . MET D 4 21  ? 139.200 105.982 86.130  1.00 63.28 ? 21  MET D CB  1 
ATOM   6324 N N   . GLU D 4 22  ? 141.681 105.619 88.079  1.00 65.89 ? 22  GLU D N   1 
ATOM   6325 C CA  . GLU D 4 22  ? 142.750 106.213 88.874  1.00 67.41 ? 22  GLU D CA  1 
ATOM   6326 C C   . GLU D 4 22  ? 144.054 105.421 88.829  1.00 66.24 ? 22  GLU D C   1 
ATOM   6327 O O   . GLU D 4 22  ? 145.083 105.937 89.279  1.00 58.58 ? 22  GLU D O   1 
ATOM   6328 C CB  . GLU D 4 22  ? 142.297 106.357 90.330  1.00 66.81 ? 22  GLU D CB  1 
ATOM   6329 C CG  . GLU D 4 22  ? 143.187 107.268 91.171  1.00 59.98 ? 22  GLU D CG  1 
ATOM   6330 C CD  . GLU D 4 22  ? 144.104 106.511 92.117  1.00 62.72 ? 22  GLU D CD  1 
ATOM   6331 O OE1 . GLU D 4 22  ? 143.646 105.546 92.765  1.00 66.37 ? 22  GLU D OE1 1 
ATOM   6332 O OE2 . GLU D 4 22  ? 145.293 106.880 92.208  1.00 60.80 ? 22  GLU D OE2 1 
ATOM   6333 N N   . ALA D 4 23  ? 144.037 104.188 88.318  1.00 71.04 ? 23  ALA D N   1 
ATOM   6334 C CA  . ALA D 4 23  ? 145.256 103.384 88.288  1.00 67.86 ? 23  ALA D CA  1 
ATOM   6335 C C   . ALA D 4 23  ? 146.325 104.008 87.401  1.00 68.14 ? 23  ALA D C   1 
ATOM   6336 O O   . ALA D 4 23  ? 147.504 104.039 87.772  1.00 69.27 ? 23  ALA D O   1 
ATOM   6337 C CB  . ALA D 4 23  ? 144.931 101.968 87.814  1.00 68.05 ? 23  ALA D CB  1 
ATOM   6338 N N   . ASN D 4 24  ? 145.939 104.508 86.228  1.00 65.99 ? 24  ASN D N   1 
ATOM   6339 C CA  . ASN D 4 24  ? 146.894 105.007 85.238  1.00 63.86 ? 24  ASN D CA  1 
ATOM   6340 C C   . ASN D 4 24  ? 147.169 106.475 85.535  1.00 62.98 ? 24  ASN D C   1 
ATOM   6341 O O   . ASN D 4 24  ? 146.488 107.372 85.036  1.00 62.77 ? 24  ASN D O   1 
ATOM   6342 C CB  . ASN D 4 24  ? 146.348 104.821 83.827  1.00 64.37 ? 24  ASN D CB  1 
ATOM   6343 C CG  . ASN D 4 24  ? 146.126 103.347 83.438  1.00 65.41 ? 24  ASN D CG  1 
ATOM   6344 O OD1 . ASN D 4 24  ? 146.762 102.470 84.021  1.00 65.04 ? 24  ASN D OD1 1 
ATOM   6345 N ND2 . ASN D 4 24  ? 145.229 103.064 82.487  1.00 64.68 ? 24  ASN D ND2 1 
ATOM   6346 N N   . ILE D 4 25  ? 148.181 106.720 86.365  1.00 59.30 ? 25  ILE D N   1 
ATOM   6347 C CA  . ILE D 4 25  ? 148.612 108.066 86.726  1.00 59.91 ? 25  ILE D CA  1 
ATOM   6348 C C   . ILE D 4 25  ? 150.132 108.108 86.666  1.00 60.49 ? 25  ILE D C   1 
ATOM   6349 O O   . ILE D 4 25  ? 150.801 107.173 87.121  1.00 59.23 ? 25  ILE D O   1 
ATOM   6350 C CB  . ILE D 4 25  ? 148.120 108.481 88.128  1.00 56.75 ? 25  ILE D CB  1 
ATOM   6351 C CG1 . ILE D 4 25  ? 146.586 108.475 88.208  1.00 62.11 ? 25  ILE D CG1 1 
ATOM   6352 C CG2 . ILE D 4 25  ? 148.666 109.852 88.502  1.00 51.49 ? 25  ILE D CG2 1 
ATOM   6353 C CD1 . ILE D 4 25  ? 145.909 109.644 87.505  1.00 61.56 ? 25  ILE D CD1 1 
ATOM   6354 N N   . ASP D 4 26  ? 150.672 109.186 86.105  1.00 59.02 ? 26  ASP D N   1 
ATOM   6355 C CA  . ASP D 4 26  ? 152.116 109.354 86.040  1.00 55.50 ? 26  ASP D CA  1 
ATOM   6356 C C   . ASP D 4 26  ? 152.675 109.702 87.415  1.00 58.74 ? 26  ASP D C   1 
ATOM   6357 O O   . ASP D 4 26  ? 152.035 110.388 88.217  1.00 58.86 ? 26  ASP D O   1 
ATOM   6358 C CB  . ASP D 4 26  ? 152.480 110.447 85.036  1.00 50.66 ? 26  ASP D CB  1 
ATOM   6359 N N   . ARG D 4 27  ? 153.885 109.215 87.683  1.00 57.12 ? 27  ARG D N   1 
ATOM   6360 C CA  . ARG D 4 27  ? 154.558 109.402 88.959  1.00 56.58 ? 27  ARG D CA  1 
ATOM   6361 C C   . ARG D 4 27  ? 156.017 109.756 88.703  1.00 54.02 ? 27  ARG D C   1 
ATOM   6362 O O   . ARG D 4 27  ? 156.562 109.495 87.627  1.00 51.28 ? 27  ARG D O   1 
ATOM   6363 C CB  . ARG D 4 27  ? 154.459 108.141 89.830  1.00 55.82 ? 27  ARG D CB  1 
ATOM   6364 C CG  . ARG D 4 27  ? 153.065 107.513 89.862  1.00 51.66 ? 27  ARG D CG  1 
ATOM   6365 C CD  . ARG D 4 27  ? 152.771 106.776 91.164  1.00 52.97 ? 27  ARG D CD  1 
ATOM   6366 N NE  . ARG D 4 27  ? 151.342 106.558 91.353  1.00 54.44 ? 27  ARG D NE  1 
ATOM   6367 C CZ  . ARG D 4 27  ? 150.604 105.709 90.649  1.00 57.68 ? 27  ARG D CZ  1 
ATOM   6368 N NH1 . ARG D 4 27  ? 151.126 104.957 89.692  1.00 56.72 ? 27  ARG D NH1 1 
ATOM   6369 N NH2 . ARG D 4 27  ? 149.304 105.608 90.912  1.00 59.29 ? 27  ARG D NH2 1 
ATOM   6370 N N   . ILE D 4 28  ? 156.648 110.362 89.712  1.00 57.17 ? 28  ILE D N   1 
ATOM   6371 C CA  . ILE D 4 28  ? 158.042 110.781 89.646  1.00 55.09 ? 28  ILE D CA  1 
ATOM   6372 C C   . ILE D 4 28  ? 158.798 110.154 90.807  1.00 52.67 ? 28  ILE D C   1 
ATOM   6373 O O   . ILE D 4 28  ? 158.219 109.523 91.693  1.00 54.14 ? 28  ILE D O   1 
ATOM   6374 C CB  . ILE D 4 28  ? 158.207 112.319 89.679  1.00 55.90 ? 28  ILE D CB  1 
ATOM   6375 C CG1 . ILE D 4 28  ? 157.601 112.912 90.962  1.00 52.61 ? 28  ILE D CG1 1 
ATOM   6376 C CG2 . ILE D 4 28  ? 157.575 112.942 88.443  1.00 58.60 ? 28  ILE D CG2 1 
ATOM   6377 C CD1 . ILE D 4 28  ? 157.617 114.421 91.008  1.00 52.09 ? 28  ILE D CD1 1 
ATOM   6378 N N   . LYS D 4 29  ? 160.112 110.354 90.796  1.00 51.85 ? 29  LYS D N   1 
ATOM   6379 C CA  . LYS D 4 29  ? 160.954 109.868 91.876  1.00 55.21 ? 29  LYS D CA  1 
ATOM   6380 C C   . LYS D 4 29  ? 160.761 110.713 93.130  1.00 56.04 ? 29  LYS D C   1 
ATOM   6381 O O   . LYS D 4 29  ? 160.635 111.944 93.076  1.00 55.76 ? 29  LYS D O   1 
ATOM   6382 C CB  . LYS D 4 29  ? 162.423 109.886 91.454  1.00 56.07 ? 29  LYS D CB  1 
ATOM   6383 N N   . VAL D 4 30  ? 160.752 110.032 94.276  1.00 51.27 ? 30  VAL D N   1 
ATOM   6384 C CA  . VAL D 4 30  ? 160.610 110.735 95.545  1.00 50.23 ? 30  VAL D CA  1 
ATOM   6385 C C   . VAL D 4 30  ? 161.813 111.634 95.783  1.00 51.02 ? 30  VAL D C   1 
ATOM   6386 O O   . VAL D 4 30  ? 161.698 112.686 96.418  1.00 53.50 ? 30  VAL D O   1 
ATOM   6387 C CB  . VAL D 4 30  ? 160.403 109.744 96.706  1.00 53.52 ? 30  VAL D CB  1 
ATOM   6388 C CG1 . VAL D 4 30  ? 159.982 110.488 97.967  1.00 47.26 ? 30  VAL D CG1 1 
ATOM   6389 C CG2 . VAL D 4 30  ? 159.344 108.703 96.349  1.00 55.80 ? 30  VAL D CG2 1 
ATOM   6390 N N   . SER D 4 31  ? 162.985 111.241 95.279  1.00 53.49 ? 31  SER D N   1 
ATOM   6391 C CA  . SER D 4 31  ? 164.152 112.108 95.386  1.00 54.80 ? 31  SER D CA  1 
ATOM   6392 C C   . SER D 4 31  ? 163.931 113.416 94.636  1.00 54.49 ? 31  SER D C   1 
ATOM   6393 O O   . SER D 4 31  ? 164.248 114.494 95.150  1.00 56.62 ? 31  SER D O   1 
ATOM   6394 C CB  . SER D 4 31  ? 165.392 111.391 94.853  1.00 55.41 ? 31  SER D CB  1 
ATOM   6395 O OG  . SER D 4 31  ? 165.282 111.152 93.461  1.00 53.10 ? 31  SER D OG  1 
ATOM   6396 N N   . LYS D 4 32  ? 163.373 113.342 93.426  1.00 44.61 ? 32  LYS D N   1 
ATOM   6397 C CA  . LYS D 4 32  ? 163.095 114.557 92.666  1.00 44.76 ? 32  LYS D CA  1 
ATOM   6398 C C   . LYS D 4 32  ? 162.045 115.415 93.362  1.00 50.96 ? 32  LYS D C   1 
ATOM   6399 O O   . LYS D 4 32  ? 162.178 116.645 93.425  1.00 52.08 ? 32  LYS D O   1 
ATOM   6400 C CB  . LYS D 4 32  ? 162.640 114.197 91.253  1.00 45.47 ? 32  LYS D CB  1 
ATOM   6401 N N   . ALA D 4 33  ? 160.989 114.785 93.887  1.00 49.46 ? 33  ALA D N   1 
ATOM   6402 C CA  . ALA D 4 33  ? 159.962 115.545 94.595  1.00 47.05 ? 33  ALA D CA  1 
ATOM   6403 C C   . ALA D 4 33  ? 160.536 116.237 95.826  1.00 47.51 ? 33  ALA D C   1 
ATOM   6404 O O   . ALA D 4 33  ? 160.258 117.419 96.075  1.00 49.57 ? 33  ALA D O   1 
ATOM   6405 C CB  . ALA D 4 33  ? 158.810 114.624 94.988  1.00 45.42 ? 33  ALA D CB  1 
ATOM   6406 N N   . ALA D 4 34  ? 161.353 115.522 96.601  1.00 47.03 ? 34  ALA D N   1 
ATOM   6407 C CA  . ALA D 4 34  ? 161.977 116.117 97.775  1.00 43.94 ? 34  ALA D CA  1 
ATOM   6408 C C   . ALA D 4 34  ? 162.907 117.255 97.382  1.00 49.94 ? 34  ALA D C   1 
ATOM   6409 O O   . ALA D 4 34  ? 162.945 118.292 98.053  1.00 49.00 ? 34  ALA D O   1 
ATOM   6410 C CB  . ALA D 4 34  ? 162.738 115.048 98.558  1.00 47.38 ? 34  ALA D CB  1 
ATOM   6411 N N   . ALA D 4 35  ? 163.671 117.079 96.300  1.00 46.95 ? 35  ALA D N   1 
ATOM   6412 C CA  . ALA D 4 35  ? 164.574 118.134 95.857  1.00 46.00 ? 35  ALA D CA  1 
ATOM   6413 C C   . ALA D 4 35  ? 163.801 119.386 95.472  1.00 46.53 ? 35  ALA D C   1 
ATOM   6414 O O   . ALA D 4 35  ? 164.203 120.502 95.819  1.00 51.20 ? 35  ALA D O   1 
ATOM   6415 C CB  . ALA D 4 35  ? 165.420 117.643 94.684  1.00 43.92 ? 35  ALA D CB  1 
ATOM   6416 N N   . ASP D 4 36  ? 162.680 119.219 94.766  1.00 39.84 ? 36  ASP D N   1 
ATOM   6417 C CA  . ASP D 4 36  ? 161.846 120.370 94.430  1.00 43.17 ? 36  ASP D CA  1 
ATOM   6418 C C   . ASP D 4 36  ? 161.302 121.038 95.688  1.00 47.08 ? 36  ASP D C   1 
ATOM   6419 O O   . ASP D 4 36  ? 161.232 122.273 95.767  1.00 43.46 ? 36  ASP D O   1 
ATOM   6420 C CB  . ASP D 4 36  ? 160.700 119.936 93.517  1.00 38.67 ? 36  ASP D CB  1 
ATOM   6421 N N   . LEU D 4 37  ? 160.914 120.238 96.684  1.00 47.86 ? 37  LEU D N   1 
ATOM   6422 C CA  . LEU D 4 37  ? 160.386 120.808 97.921  1.00 39.57 ? 37  LEU D CA  1 
ATOM   6423 C C   . LEU D 4 37  ? 161.441 121.634 98.652  1.00 40.69 ? 37  LEU D C   1 
ATOM   6424 O O   . LEU D 4 37  ? 161.166 122.763 99.078  1.00 44.12 ? 37  LEU D O   1 
ATOM   6425 C CB  . LEU D 4 37  ? 159.859 119.695 98.825  1.00 43.52 ? 37  LEU D CB  1 
ATOM   6426 C CG  . LEU D 4 37  ? 158.852 120.120 99.893  1.00 46.80 ? 37  LEU D CG  1 
ATOM   6427 C CD1 . LEU D 4 37  ? 157.503 120.454 99.272  1.00 41.42 ? 37  LEU D CD1 1 
ATOM   6428 C CD2 . LEU D 4 37  ? 158.703 119.031 100.942 1.00 47.88 ? 37  LEU D CD2 1 
ATOM   6429 N N   . MET D 4 38  ? 162.654 121.093 98.809  1.00 46.52 ? 38  MET D N   1 
ATOM   6430 C CA  . MET D 4 38  ? 163.709 121.868 99.463  1.00 46.79 ? 38  MET D CA  1 
ATOM   6431 C C   . MET D 4 38  ? 164.090 123.090 98.639  1.00 47.26 ? 38  MET D C   1 
ATOM   6432 O O   . MET D 4 38  ? 164.417 124.141 99.203  1.00 48.42 ? 38  MET D O   1 
ATOM   6433 C CB  . MET D 4 38  ? 164.957 121.023 99.736  1.00 47.76 ? 38  MET D CB  1 
ATOM   6434 C CG  . MET D 4 38  ? 164.718 119.666 100.377 1.00 47.65 ? 38  MET D CG  1 
ATOM   6435 S SD  . MET D 4 38  ? 166.127 118.961 101.272 1.00 60.84 ? 38  MET D SD  1 
ATOM   6436 C CE  . MET D 4 38  ? 167.544 119.728 100.479 1.00 49.34 ? 38  MET D CE  1 
ATOM   6437 N N   . ALA D 4 39  ? 164.072 122.975 97.310  1.00 47.29 ? 39  ALA D N   1 
ATOM   6438 C CA  . ALA D 4 39  ? 164.379 124.126 96.469  1.00 48.99 ? 39  ALA D CA  1 
ATOM   6439 C C   . ALA D 4 39  ? 163.382 125.251 96.705  1.00 47.36 ? 39  ALA D C   1 
ATOM   6440 O O   . ALA D 4 39  ? 163.770 126.411 96.887  1.00 50.71 ? 39  ALA D O   1 
ATOM   6441 C CB  . ALA D 4 39  ? 164.388 123.712 94.998  1.00 50.04 ? 39  ALA D CB  1 
ATOM   6442 N N   . TYR D 4 40  ? 162.087 124.924 96.729  1.00 40.19 ? 40  TYR D N   1 
ATOM   6443 C CA  . TYR D 4 40  ? 161.091 125.959 96.987  1.00 44.01 ? 40  TYR D CA  1 
ATOM   6444 C C   . TYR D 4 40  ? 161.230 126.524 98.394  1.00 40.35 ? 40  TYR D C   1 
ATOM   6445 O O   . TYR D 4 40  ? 161.080 127.734 98.596  1.00 37.10 ? 40  TYR D O   1 
ATOM   6446 C CB  . TYR D 4 40  ? 159.677 125.421 96.780  1.00 42.07 ? 40  TYR D CB  1 
ATOM   6447 C CG  . TYR D 4 40  ? 158.620 126.459 97.085  1.00 37.66 ? 40  TYR D CG  1 
ATOM   6448 C CD1 . TYR D 4 40  ? 158.321 127.458 96.171  1.00 42.53 ? 40  TYR D CD1 1 
ATOM   6449 C CD2 . TYR D 4 40  ? 157.941 126.457 98.295  1.00 34.69 ? 40  TYR D CD2 1 
ATOM   6450 C CE1 . TYR D 4 40  ? 157.367 128.415 96.446  1.00 41.75 ? 40  TYR D CE1 1 
ATOM   6451 C CE2 . TYR D 4 40  ? 156.986 127.411 98.578  1.00 37.00 ? 40  TYR D CE2 1 
ATOM   6452 C CZ  . TYR D 4 40  ? 156.703 128.387 97.650  1.00 37.23 ? 40  TYR D CZ  1 
ATOM   6453 O OH  . TYR D 4 40  ? 155.751 129.341 97.927  1.00 36.77 ? 40  TYR D OH  1 
ATOM   6454 N N   . CYS D 4 41  ? 161.497 125.669 99.383  1.00 42.80 ? 41  CYS D N   1 
ATOM   6455 C CA  . CYS D 4 41  ? 161.627 126.162 100.749 1.00 40.50 ? 41  CYS D CA  1 
ATOM   6456 C C   . CYS D 4 41  ? 162.822 127.089 100.920 1.00 48.16 ? 41  CYS D C   1 
ATOM   6457 O O   . CYS D 4 41  ? 162.706 128.099 101.623 1.00 53.04 ? 41  CYS D O   1 
ATOM   6458 C CB  . CYS D 4 41  ? 161.733 124.996 101.731 1.00 42.90 ? 41  CYS D CB  1 
ATOM   6459 S SG  . CYS D 4 41  ? 160.133 124.390 102.300 1.00 64.91 ? 41  CYS D SG  1 
ATOM   6460 N N   . GLU D 4 42  ? 163.959 126.778 100.298 1.00 53.04 ? 42  GLU D N   1 
ATOM   6461 C CA  . GLU D 4 42  ? 165.137 127.629 100.400 1.00 54.14 ? 42  GLU D CA  1 
ATOM   6462 C C   . GLU D 4 42  ? 165.086 128.834 99.471  1.00 52.58 ? 42  GLU D C   1 
ATOM   6463 O O   . GLU D 4 42  ? 165.856 129.780 99.670  1.00 50.57 ? 42  GLU D O   1 
ATOM   6464 C CB  . GLU D 4 42  ? 166.401 126.816 100.103 1.00 51.87 ? 42  GLU D CB  1 
ATOM   6465 C CG  . GLU D 4 42  ? 166.737 125.794 101.177 1.00 52.46 ? 42  GLU D CG  1 
ATOM   6466 C CD  . GLU D 4 42  ? 168.162 125.288 101.076 1.00 56.28 ? 42  GLU D CD  1 
ATOM   6467 O OE1 . GLU D 4 42  ? 168.743 124.937 102.124 1.00 54.44 ? 42  GLU D OE1 1 
ATOM   6468 O OE2 . GLU D 4 42  ? 168.700 125.241 99.950  1.00 55.96 ? 42  GLU D OE2 1 
ATOM   6469 N N   . ALA D 4 43  ? 164.205 128.828 98.467  1.00 52.99 ? 43  ALA D N   1 
ATOM   6470 C CA  . ALA D 4 43  ? 164.055 130.009 97.625  1.00 51.74 ? 43  ALA D CA  1 
ATOM   6471 C C   . ALA D 4 43  ? 163.425 131.170 98.384  1.00 48.80 ? 43  ALA D C   1 
ATOM   6472 O O   . ALA D 4 43  ? 163.787 132.328 98.147  1.00 45.84 ? 43  ALA D O   1 
ATOM   6473 C CB  . ALA D 4 43  ? 163.219 129.671 96.393  1.00 50.64 ? 43  ALA D CB  1 
ATOM   6474 N N   . HIS D 4 44  ? 162.491 130.884 99.292  1.00 46.49 ? 44  HIS D N   1 
ATOM   6475 C CA  . HIS D 4 44  ? 161.764 131.898 100.051 1.00 46.36 ? 44  HIS D CA  1 
ATOM   6476 C C   . HIS D 4 44  ? 162.200 131.928 101.513 1.00 45.81 ? 44  HIS D C   1 
ATOM   6477 O O   . HIS D 4 44  ? 161.420 132.273 102.401 1.00 46.26 ? 44  HIS D O   1 
ATOM   6478 C CB  . HIS D 4 44  ? 160.259 131.663 99.961  1.00 45.79 ? 44  HIS D CB  1 
ATOM   6479 C CG  . HIS D 4 44  ? 159.729 131.646 98.561  1.00 47.77 ? 44  HIS D CG  1 
ATOM   6480 N ND1 . HIS D 4 44  ? 160.473 132.056 97.476  1.00 50.40 ? 44  HIS D ND1 1 
ATOM   6481 C CD2 . HIS D 4 44  ? 158.523 131.277 98.070  1.00 47.97 ? 44  HIS D CD2 1 
ATOM   6482 C CE1 . HIS D 4 44  ? 159.751 131.934 96.377  1.00 46.90 ? 44  HIS D CE1 1 
ATOM   6483 N NE2 . HIS D 4 44  ? 158.563 131.464 96.710  1.00 47.34 ? 44  HIS D NE2 1 
ATOM   6484 N N   . ALA D 4 45  ? 163.458 131.573 101.780 1.00 49.08 ? 45  ALA D N   1 
ATOM   6485 C CA  . ALA D 4 45  ? 163.950 131.585 103.154 1.00 53.02 ? 45  ALA D CA  1 
ATOM   6486 C C   . ALA D 4 45  ? 163.964 132.998 103.724 1.00 54.60 ? 45  ALA D C   1 
ATOM   6487 O O   . ALA D 4 45  ? 163.666 133.199 104.908 1.00 50.41 ? 45  ALA D O   1 
ATOM   6488 C CB  . ALA D 4 45  ? 165.347 130.969 103.215 1.00 51.40 ? 45  ALA D CB  1 
ATOM   6489 N N   . LYS D 4 46  ? 164.308 133.987 102.902 1.00 52.71 ? 46  LYS D N   1 
ATOM   6490 C CA  . LYS D 4 46  ? 164.394 135.375 103.336 1.00 51.13 ? 46  LYS D CA  1 
ATOM   6491 C C   . LYS D 4 46  ? 163.056 136.106 103.296 1.00 50.82 ? 46  LYS D C   1 
ATOM   6492 O O   . LYS D 4 46  ? 162.988 137.252 103.753 1.00 50.06 ? 46  LYS D O   1 
ATOM   6493 C CB  . LYS D 4 46  ? 165.408 136.128 102.469 1.00 49.89 ? 46  LYS D CB  1 
ATOM   6494 N N   . GLU D 4 47  ? 162.000 135.481 102.774 1.00 43.89 ? 47  GLU D N   1 
ATOM   6495 C CA  . GLU D 4 47  ? 160.683 136.096 102.663 1.00 43.51 ? 47  GLU D CA  1 
ATOM   6496 C C   . GLU D 4 47  ? 159.686 135.541 103.672 1.00 45.03 ? 47  GLU D C   1 
ATOM   6497 O O   . GLU D 4 47  ? 158.477 135.607 103.429 1.00 46.33 ? 47  GLU D O   1 
ATOM   6498 C CB  . GLU D 4 47  ? 160.139 135.909 101.246 1.00 44.37 ? 47  GLU D CB  1 
ATOM   6499 C CG  . GLU D 4 47  ? 159.287 137.065 100.755 1.00 45.05 ? 47  GLU D CG  1 
ATOM   6500 C CD  . GLU D 4 47  ? 158.859 136.900 99.311  1.00 51.30 ? 47  GLU D CD  1 
ATOM   6501 O OE1 . GLU D 4 47  ? 158.524 135.764 98.915  1.00 47.94 ? 47  GLU D OE1 1 
ATOM   6502 O OE2 . GLU D 4 47  ? 158.857 137.906 98.571  1.00 52.25 ? 47  GLU D OE2 1 
ATOM   6503 N N   . ASP D 4 48  ? 160.163 135.005 104.797 1.00 39.70 ? 48  ASP D N   1 
ATOM   6504 C CA  . ASP D 4 48  ? 159.315 134.403 105.822 1.00 35.92 ? 48  ASP D CA  1 
ATOM   6505 C C   . ASP D 4 48  ? 159.387 135.224 107.109 1.00 37.07 ? 48  ASP D C   1 
ATOM   6506 O O   . ASP D 4 48  ? 160.371 135.116 107.857 1.00 39.48 ? 48  ASP D O   1 
ATOM   6507 C CB  . ASP D 4 48  ? 159.749 132.958 106.080 1.00 37.23 ? 48  ASP D CB  1 
ATOM   6508 C CG  . ASP D 4 48  ? 158.593 132.072 106.468 1.00 36.21 ? 48  ASP D CG  1 
ATOM   6509 O OD1 . ASP D 4 48  ? 157.810 132.473 107.353 1.00 38.09 ? 48  ASP D OD1 1 
ATOM   6510 O OD2 . ASP D 4 48  ? 158.460 130.972 105.897 1.00 39.55 ? 48  ASP D OD2 1 
ATOM   6511 N N   . PRO D 4 49  ? 158.394 136.072 107.412 1.00 32.75 ? 49  PRO D N   1 
ATOM   6512 C CA  . PRO D 4 49  ? 158.471 136.863 108.653 1.00 31.06 ? 49  PRO D CA  1 
ATOM   6513 C C   . PRO D 4 49  ? 158.435 136.037 109.927 1.00 30.51 ? 49  PRO D C   1 
ATOM   6514 O O   . PRO D 4 49  ? 158.829 136.553 110.979 1.00 39.04 ? 49  PRO D O   1 
ATOM   6515 C CB  . PRO D 4 49  ? 157.250 137.786 108.560 1.00 29.71 ? 49  PRO D CB  1 
ATOM   6516 C CG  . PRO D 4 49  ? 156.931 137.848 107.118 1.00 38.34 ? 49  PRO D CG  1 
ATOM   6517 C CD  . PRO D 4 49  ? 157.261 136.503 106.575 1.00 34.27 ? 49  PRO D CD  1 
ATOM   6518 N N   . LEU D 4 50  ? 157.966 134.790 109.879 1.00 36.76 ? 50  LEU D N   1 
ATOM   6519 C CA  . LEU D 4 50  ? 157.911 133.949 111.071 1.00 40.50 ? 50  LEU D CA  1 
ATOM   6520 C C   . LEU D 4 50  ? 159.188 133.144 111.266 1.00 34.83 ? 50  LEU D C   1 
ATOM   6521 O O   . LEU D 4 50  ? 159.578 132.870 112.406 1.00 31.28 ? 50  LEU D O   1 
ATOM   6522 C CB  . LEU D 4 50  ? 156.712 133.002 110.992 1.00 35.57 ? 50  LEU D CB  1 
ATOM   6523 C CG  . LEU D 4 50  ? 155.340 133.675 111.055 1.00 29.77 ? 50  LEU D CG  1 
ATOM   6524 C CD1 . LEU D 4 50  ? 154.263 132.750 110.523 1.00 33.50 ? 50  LEU D CD1 1 
ATOM   6525 C CD2 . LEU D 4 50  ? 155.014 134.116 112.472 1.00 34.05 ? 50  LEU D CD2 1 
ATOM   6526 N N   . LEU D 4 51  ? 159.847 132.754 110.174 1.00 35.11 ? 51  LEU D N   1 
ATOM   6527 C CA  . LEU D 4 51  ? 161.107 132.030 110.298 1.00 35.90 ? 51  LEU D CA  1 
ATOM   6528 C C   . LEU D 4 51  ? 162.207 132.946 110.815 1.00 44.75 ? 51  LEU D C   1 
ATOM   6529 O O   . LEU D 4 51  ? 163.010 132.547 111.667 1.00 46.08 ? 51  LEU D O   1 
ATOM   6530 C CB  . LEU D 4 51  ? 161.501 131.439 108.945 1.00 39.42 ? 51  LEU D CB  1 
ATOM   6531 C CG  . LEU D 4 51  ? 162.621 130.398 108.927 1.00 35.12 ? 51  LEU D CG  1 
ATOM   6532 C CD1 . LEU D 4 51  ? 162.077 129.029 109.280 1.00 39.54 ? 51  LEU D CD1 1 
ATOM   6533 C CD2 . LEU D 4 51  ? 163.309 130.367 107.568 1.00 41.37 ? 51  LEU D CD2 1 
ATOM   6534 N N   . THR D 4 52  ? 162.252 134.185 110.313 1.00 50.40 ? 52  THR D N   1 
ATOM   6535 C CA  . THR D 4 52  ? 163.245 135.183 110.678 1.00 51.76 ? 52  THR D CA  1 
ATOM   6536 C C   . THR D 4 52  ? 162.587 136.278 111.506 1.00 50.25 ? 52  THR D C   1 
ATOM   6537 O O   . THR D 4 52  ? 161.504 136.740 111.126 1.00 50.52 ? 52  THR D O   1 
ATOM   6538 C CB  . THR D 4 52  ? 163.875 135.801 109.424 1.00 52.53 ? 52  THR D CB  1 
ATOM   6539 O OG1 . THR D 4 52  ? 162.843 136.224 108.526 1.00 47.28 ? 52  THR D OG1 1 
ATOM   6540 C CG2 . THR D 4 52  ? 164.768 134.794 108.719 1.00 51.80 ? 52  THR D CG2 1 
ATOM   6541 N N   . PRO D 4 53  ? 163.174 136.739 112.614 1.00 63.86 ? 53  PRO D N   1 
ATOM   6542 C CA  . PRO D 4 53  ? 162.554 137.851 113.340 1.00 64.35 ? 53  PRO D CA  1 
ATOM   6543 C C   . PRO D 4 53  ? 162.638 139.138 112.534 1.00 65.26 ? 53  PRO D C   1 
ATOM   6544 O O   . PRO D 4 53  ? 163.404 139.251 111.574 1.00 64.19 ? 53  PRO D O   1 
ATOM   6545 C CB  . PRO D 4 53  ? 163.375 137.942 114.631 1.00 67.13 ? 53  PRO D CB  1 
ATOM   6546 C CG  . PRO D 4 53  ? 164.700 137.406 114.261 1.00 67.90 ? 53  PRO D CG  1 
ATOM   6547 C CD  . PRO D 4 53  ? 164.442 136.328 113.249 1.00 64.81 ? 53  PRO D CD  1 
ATOM   6548 N N   . VAL D 4 54  ? 161.824 140.112 112.934 1.00 67.65 ? 54  VAL D N   1 
ATOM   6549 C CA  . VAL D 4 54  ? 161.766 141.417 112.276 1.00 67.41 ? 54  VAL D CA  1 
ATOM   6550 C C   . VAL D 4 54  ? 161.905 142.501 113.341 1.00 64.86 ? 54  VAL D C   1 
ATOM   6551 O O   . VAL D 4 54  ? 161.467 142.295 114.481 1.00 62.86 ? 54  VAL D O   1 
ATOM   6552 C CB  . VAL D 4 54  ? 160.460 141.590 111.483 1.00 63.46 ? 54  VAL D CB  1 
ATOM   6553 C CG1 . VAL D 4 54  ? 160.566 140.902 110.133 1.00 58.67 ? 54  VAL D CG1 1 
ATOM   6554 C CG2 . VAL D 4 54  ? 159.267 141.056 112.272 1.00 62.14 ? 54  VAL D CG2 1 
ATOM   6555 N N   . PRO D 4 55  ? 162.495 143.659 113.038 1.00 65.59 ? 55  PRO D N   1 
ATOM   6556 C CA  . PRO D 4 55  ? 162.550 144.723 114.044 1.00 66.78 ? 55  PRO D CA  1 
ATOM   6557 C C   . PRO D 4 55  ? 161.180 145.337 114.277 1.00 63.01 ? 55  PRO D C   1 
ATOM   6558 O O   . PRO D 4 55  ? 160.286 145.265 113.431 1.00 61.18 ? 55  PRO D O   1 
ATOM   6559 C CB  . PRO D 4 55  ? 163.524 145.740 113.439 1.00 69.15 ? 55  PRO D CB  1 
ATOM   6560 C CG  . PRO D 4 55  ? 163.432 145.520 111.981 1.00 69.29 ? 55  PRO D CG  1 
ATOM   6561 C CD  . PRO D 4 55  ? 163.206 144.048 111.806 1.00 66.54 ? 55  PRO D CD  1 
ATOM   6562 N N   . ALA D 4 56  ? 161.026 145.955 115.450 1.00 67.46 ? 56  ALA D N   1 
ATOM   6563 C CA  . ALA D 4 56  ? 159.759 146.583 115.802 1.00 69.77 ? 56  ALA D CA  1 
ATOM   6564 C C   . ALA D 4 56  ? 159.392 147.727 114.865 1.00 72.67 ? 56  ALA D C   1 
ATOM   6565 O O   . ALA D 4 56  ? 158.207 148.057 114.746 1.00 71.57 ? 56  ALA D O   1 
ATOM   6566 C CB  . ALA D 4 56  ? 159.813 147.094 117.243 1.00 67.92 ? 56  ALA D CB  1 
ATOM   6567 N N   . SER D 4 57  ? 160.376 148.344 114.203 1.00 73.03 ? 57  SER D N   1 
ATOM   6568 C CA  . SER D 4 57  ? 160.081 149.462 113.311 1.00 71.77 ? 57  SER D CA  1 
ATOM   6569 C C   . SER D 4 57  ? 159.226 149.031 112.127 1.00 68.32 ? 57  SER D C   1 
ATOM   6570 O O   . SER D 4 57  ? 158.354 149.790 111.689 1.00 69.31 ? 57  SER D O   1 
ATOM   6571 C CB  . SER D 4 57  ? 161.383 150.097 112.822 1.00 71.94 ? 57  SER D CB  1 
ATOM   6572 O OG  . SER D 4 57  ? 161.122 151.159 111.921 1.00 74.94 ? 57  SER D OG  1 
ATOM   6573 N N   . GLU D 4 58  ? 159.458 147.827 111.601 1.00 63.25 ? 58  GLU D N   1 
ATOM   6574 C CA  . GLU D 4 58  ? 158.689 147.298 110.480 1.00 65.30 ? 58  GLU D CA  1 
ATOM   6575 C C   . GLU D 4 58  ? 157.531 146.408 110.909 1.00 61.95 ? 58  GLU D C   1 
ATOM   6576 O O   . GLU D 4 58  ? 156.558 146.284 110.157 1.00 57.49 ? 58  GLU D O   1 
ATOM   6577 C CB  . GLU D 4 58  ? 159.592 146.496 109.526 1.00 63.17 ? 58  GLU D CB  1 
ATOM   6578 C CG  . GLU D 4 58  ? 160.905 147.191 109.098 1.00 63.71 ? 58  GLU D CG  1 
ATOM   6579 C CD  . GLU D 4 58  ? 162.002 146.222 108.670 1.00 64.38 ? 58  GLU D CD  1 
ATOM   6580 O OE1 . GLU D 4 58  ? 161.861 144.997 108.870 1.00 66.27 ? 58  GLU D OE1 1 
ATOM   6581 O OE2 . GLU D 4 58  ? 163.021 146.697 108.124 1.00 64.63 ? 58  GLU D OE2 1 
ATOM   6582 N N   . ASN D 4 59  ? 157.612 145.789 112.078 1.00 58.77 ? 59  ASN D N   1 
ATOM   6583 C CA  . ASN D 4 59  ? 156.548 144.910 112.554 1.00 53.74 ? 59  ASN D CA  1 
ATOM   6584 C C   . ASN D 4 59  ? 155.263 145.711 112.755 1.00 56.51 ? 59  ASN D C   1 
ATOM   6585 O O   . ASN D 4 59  ? 155.286 146.705 113.493 1.00 56.53 ? 59  ASN D O   1 
ATOM   6586 C CB  . ASN D 4 59  ? 156.969 144.258 113.866 1.00 54.51 ? 59  ASN D CB  1 
ATOM   6587 C CG  . ASN D 4 59  ? 155.873 143.415 114.478 1.00 51.26 ? 59  ASN D CG  1 
ATOM   6588 O OD1 . ASN D 4 59  ? 155.034 142.860 113.774 1.00 49.22 ? 59  ASN D OD1 1 
ATOM   6589 N ND2 . ASN D 4 59  ? 155.869 143.324 115.800 1.00 51.81 ? 59  ASN D ND2 1 
ATOM   6590 N N   . PRO D 4 60  ? 154.131 145.339 112.144 1.00 45.81 ? 60  PRO D N   1 
ATOM   6591 C CA  . PRO D 4 60  ? 152.905 146.118 112.356 1.00 44.45 ? 60  PRO D CA  1 
ATOM   6592 C C   . PRO D 4 60  ? 152.146 145.770 113.626 1.00 39.25 ? 60  PRO D C   1 
ATOM   6593 O O   . PRO D 4 60  ? 151.180 146.471 113.950 1.00 43.65 ? 60  PRO D O   1 
ATOM   6594 C CB  . PRO D 4 60  ? 152.072 145.779 111.116 1.00 39.32 ? 60  PRO D CB  1 
ATOM   6595 C CG  . PRO D 4 60  ? 152.447 144.403 110.801 1.00 39.95 ? 60  PRO D CG  1 
ATOM   6596 C CD  . PRO D 4 60  ? 153.900 144.259 111.163 1.00 39.23 ? 60  PRO D CD  1 
ATOM   6597 N N   . PHE D 4 61  ? 152.547 144.727 114.349 1.00 27.65 ? 61  PHE D N   1 
ATOM   6598 C CA  . PHE D 4 61  ? 151.911 144.367 115.613 1.00 32.63 ? 61  PHE D CA  1 
ATOM   6599 C C   . PHE D 4 61  ? 152.723 144.892 116.792 1.00 37.51 ? 61  PHE D C   1 
ATOM   6600 O O   . PHE D 4 61  ? 153.325 145.963 116.717 1.00 35.50 ? 61  PHE D O   1 
ATOM   6601 C CB  . PHE D 4 61  ? 151.747 142.851 115.726 1.00 35.65 ? 61  PHE D CB  1 
ATOM   6602 C CG  . PHE D 4 61  ? 150.723 142.278 114.786 1.00 39.46 ? 61  PHE D CG  1 
ATOM   6603 C CD1 . PHE D 4 61  ? 151.015 142.090 113.448 1.00 39.79 ? 61  PHE D CD1 1 
ATOM   6604 C CD2 . PHE D 4 61  ? 149.464 141.936 115.243 1.00 40.47 ? 61  PHE D CD2 1 
ATOM   6605 C CE1 . PHE D 4 61  ? 150.071 141.565 112.585 1.00 31.35 ? 61  PHE D CE1 1 
ATOM   6606 C CE2 . PHE D 4 61  ? 148.519 141.413 114.385 1.00 34.89 ? 61  PHE D CE2 1 
ATOM   6607 C CZ  . PHE D 4 61  ? 148.823 141.228 113.055 1.00 23.38 ? 61  PHE D CZ  1 
ATOM   6608 N N   . VAL E 5 2   ? 116.943 154.841 100.133 1.00 36.40 ? 2   VAL E N   1 
ATOM   6609 C CA  . VAL E 5 2   ? 117.927 155.669 100.818 1.00 30.49 ? 2   VAL E CA  1 
ATOM   6610 C C   . VAL E 5 2   ? 117.689 157.137 100.464 1.00 25.78 ? 2   VAL E C   1 
ATOM   6611 O O   . VAL E 5 2   ? 118.007 157.589 99.367  1.00 29.46 ? 2   VAL E O   1 
ATOM   6612 C CB  . VAL E 5 2   ? 119.380 155.213 100.490 1.00 24.71 ? 2   VAL E CB  1 
ATOM   6613 C CG1 . VAL E 5 2   ? 119.673 155.214 98.980  1.00 24.81 ? 2   VAL E CG1 1 
ATOM   6614 C CG2 . VAL E 5 2   ? 120.389 156.071 101.231 1.00 31.95 ? 2   VAL E CG2 1 
ATOM   6615 N N   . GLN E 5 3   ? 117.090 157.866 101.404 1.00 18.11 ? 3   GLN E N   1 
ATOM   6616 C CA  . GLN E 5 3   ? 116.759 159.272 101.225 1.00 24.40 ? 3   GLN E CA  1 
ATOM   6617 C C   . GLN E 5 3   ? 117.054 160.031 102.509 1.00 33.86 ? 3   GLN E C   1 
ATOM   6618 O O   . GLN E 5 3   ? 117.106 159.451 103.596 1.00 36.55 ? 3   GLN E O   1 
ATOM   6619 C CB  . GLN E 5 3   ? 115.280 159.481 100.853 1.00 23.16 ? 3   GLN E CB  1 
ATOM   6620 C CG  . GLN E 5 3   ? 114.848 158.891 99.510  1.00 29.04 ? 3   GLN E CG  1 
ATOM   6621 C CD  . GLN E 5 3   ? 114.880 159.892 98.362  1.00 32.48 ? 3   GLN E CD  1 
ATOM   6622 O OE1 . GLN E 5 3   ? 115.248 161.054 98.534  1.00 27.71 ? 3   GLN E OE1 1 
ATOM   6623 N NE2 . GLN E 5 3   ? 114.486 159.437 97.179  1.00 32.67 ? 3   GLN E NE2 1 
ATOM   6624 N N   . LEU E 5 4   ? 117.253 161.338 102.365 1.00 27.34 ? 4   LEU E N   1 
ATOM   6625 C CA  . LEU E 5 4   ? 117.325 162.265 103.483 1.00 16.63 ? 4   LEU E CA  1 
ATOM   6626 C C   . LEU E 5 4   ? 116.570 163.530 103.112 1.00 18.83 ? 4   LEU E C   1 
ATOM   6627 O O   . LEU E 5 4   ? 117.014 164.294 102.252 1.00 33.02 ? 4   LEU E O   1 
ATOM   6628 C CB  . LEU E 5 4   ? 118.771 162.615 103.844 1.00 22.98 ? 4   LEU E CB  1 
ATOM   6629 C CG  . LEU E 5 4   ? 119.666 161.480 104.339 1.00 21.91 ? 4   LEU E CG  1 
ATOM   6630 C CD1 . LEU E 5 4   ? 121.119 161.915 104.358 1.00 20.45 ? 4   LEU E CD1 1 
ATOM   6631 C CD2 . LEU E 5 4   ? 119.234 161.029 105.719 1.00 27.61 ? 4   LEU E CD2 1 
ATOM   6632 N N   . VAL E 5 5   ? 115.432 163.744 103.766 1.00 12.05 ? 5   VAL E N   1 
ATOM   6633 C CA  . VAL E 5 5   ? 114.594 164.914 103.543 1.00 20.48 ? 5   VAL E CA  1 
ATOM   6634 C C   . VAL E 5 5   ? 114.757 165.833 104.743 1.00 33.54 ? 5   VAL E C   1 
ATOM   6635 O O   . VAL E 5 5   ? 115.018 165.379 105.862 1.00 40.36 ? 5   VAL E O   1 
ATOM   6636 C CB  . VAL E 5 5   ? 113.111 164.532 103.333 1.00 25.31 ? 5   VAL E CB  1 
ATOM   6637 C CG1 . VAL E 5 5   ? 112.277 165.759 102.974 1.00 27.71 ? 5   VAL E CG1 1 
ATOM   6638 C CG2 . VAL E 5 5   ? 112.986 163.460 102.257 1.00 25.41 ? 5   VAL E CG2 1 
ATOM   6639 N N   . GLU E 5 6   ? 114.610 167.135 104.502 1.00 27.61 ? 6   GLU E N   1 
ATOM   6640 C CA  . GLU E 5 6   ? 114.820 168.156 105.516 1.00 29.87 ? 6   GLU E CA  1 
ATOM   6641 C C   . GLU E 5 6   ? 113.643 169.120 105.517 1.00 38.04 ? 6   GLU E C   1 
ATOM   6642 O O   . GLU E 5 6   ? 112.984 169.320 104.493 1.00 41.89 ? 6   GLU E O   1 
ATOM   6643 C CB  . GLU E 5 6   ? 116.112 168.926 105.263 1.00 24.53 ? 6   GLU E CB  1 
ATOM   6644 C CG  . GLU E 5 6   ? 117.380 168.100 105.394 1.00 23.85 ? 6   GLU E CG  1 
ATOM   6645 C CD  . GLU E 5 6   ? 118.499 168.603 104.500 1.00 31.53 ? 6   GLU E CD  1 
ATOM   6646 O OE1 . GLU E 5 6   ? 118.425 169.757 104.034 1.00 27.76 ? 6   GLU E OE1 1 
ATOM   6647 O OE2 . GLU E 5 6   ? 119.446 167.838 104.240 1.00 30.01 ? 6   GLU E OE2 1 
ATOM   6648 N N   . SER E 5 7   ? 113.385 169.715 106.682 1.00 36.12 ? 7   SER E N   1 
ATOM   6649 C CA  . SER E 5 7   ? 112.279 170.644 106.871 1.00 40.30 ? 7   SER E CA  1 
ATOM   6650 C C   . SER E 5 7   ? 112.745 171.845 107.680 1.00 46.89 ? 7   SER E C   1 
ATOM   6651 O O   . SER E 5 7   ? 113.672 171.738 108.489 1.00 44.40 ? 7   SER E O   1 
ATOM   6652 C CB  . SER E 5 7   ? 111.102 169.963 107.578 1.00 41.15 ? 7   SER E CB  1 
ATOM   6653 O OG  . SER E 5 7   ? 111.445 169.594 108.903 1.00 38.40 ? 7   SER E OG  1 
ATOM   6654 N N   . GLY E 5 8   ? 112.101 172.982 107.450 1.00 61.90 ? 8   GLY E N   1 
ATOM   6655 C CA  . GLY E 5 8   ? 112.381 174.211 108.165 1.00 56.39 ? 8   GLY E CA  1 
ATOM   6656 C C   . GLY E 5 8   ? 113.186 175.182 107.325 1.00 55.17 ? 8   GLY E C   1 
ATOM   6657 O O   . GLY E 5 8   ? 113.898 174.810 106.392 1.00 55.06 ? 8   GLY E O   1 
ATOM   6658 N N   . GLY E 5 9   ? 113.063 176.459 107.692 1.00 54.30 ? 9   GLY E N   1 
ATOM   6659 C CA  . GLY E 5 9   ? 113.713 177.545 106.987 1.00 54.81 ? 9   GLY E CA  1 
ATOM   6660 C C   . GLY E 5 9   ? 112.814 178.768 106.898 1.00 58.63 ? 9   GLY E C   1 
ATOM   6661 O O   . GLY E 5 9   ? 111.964 179.000 107.767 1.00 61.45 ? 9   GLY E O   1 
ATOM   6662 N N   . GLY E 5 10  ? 113.015 179.548 105.839 1.00 46.83 ? 10  GLY E N   1 
ATOM   6663 C CA  . GLY E 5 10  ? 112.225 180.735 105.597 1.00 45.68 ? 10  GLY E CA  1 
ATOM   6664 C C   . GLY E 5 10  ? 112.771 181.959 106.310 1.00 45.93 ? 10  GLY E C   1 
ATOM   6665 O O   . GLY E 5 10  ? 113.816 181.934 106.964 1.00 48.02 ? 10  GLY E O   1 
ATOM   6666 N N   . LEU E 5 11  ? 112.037 183.062 106.166 1.00 47.43 ? 11  LEU E N   1 
ATOM   6667 C CA  . LEU E 5 11  ? 112.435 184.320 106.783 1.00 51.38 ? 11  LEU E CA  1 
ATOM   6668 C C   . LEU E 5 11  ? 112.465 184.178 108.299 1.00 47.77 ? 11  LEU E C   1 
ATOM   6669 O O   . LEU E 5 11  ? 111.550 183.607 108.899 1.00 49.32 ? 11  LEU E O   1 
ATOM   6670 C CB  . LEU E 5 11  ? 111.465 185.436 106.390 1.00 50.20 ? 11  LEU E CB  1 
ATOM   6671 C CG  . LEU E 5 11  ? 111.411 185.974 104.953 1.00 49.58 ? 11  LEU E CG  1 
ATOM   6672 C CD1 . LEU E 5 11  ? 110.804 187.367 104.964 1.00 48.24 ? 11  LEU E CD1 1 
ATOM   6673 C CD2 . LEU E 5 11  ? 112.761 185.995 104.258 1.00 43.80 ? 11  LEU E CD2 1 
ATOM   6674 N N   . VAL E 5 12  ? 113.525 184.693 108.916 1.00 41.98 ? 12  VAL E N   1 
ATOM   6675 C CA  . VAL E 5 12  ? 113.677 184.705 110.366 1.00 42.91 ? 12  VAL E CA  1 
ATOM   6676 C C   . VAL E 5 12  ? 114.315 186.026 110.763 1.00 47.32 ? 12  VAL E C   1 
ATOM   6677 O O   . VAL E 5 12  ? 115.346 186.414 110.204 1.00 51.33 ? 12  VAL E O   1 
ATOM   6678 C CB  . VAL E 5 12  ? 114.535 183.529 110.869 1.00 40.63 ? 12  VAL E CB  1 
ATOM   6679 C CG1 . VAL E 5 12  ? 114.712 183.617 112.375 1.00 38.80 ? 12  VAL E CG1 1 
ATOM   6680 C CG2 . VAL E 5 12  ? 113.918 182.194 110.466 1.00 44.93 ? 12  VAL E CG2 1 
ATOM   6681 N N   . GLN E 5 13  ? 113.713 186.710 111.723 1.00 51.11 ? 13  GLN E N   1 
ATOM   6682 C CA  . GLN E 5 13  ? 114.317 187.944 112.192 1.00 47.78 ? 13  GLN E CA  1 
ATOM   6683 C C   . GLN E 5 13  ? 115.585 187.628 112.987 1.00 45.02 ? 13  GLN E C   1 
ATOM   6684 O O   . GLN E 5 13  ? 115.712 186.537 113.548 1.00 46.93 ? 13  GLN E O   1 
ATOM   6685 C CB  . GLN E 5 13  ? 113.341 188.726 113.066 1.00 45.38 ? 13  GLN E CB  1 
ATOM   6686 C CG  . GLN E 5 13  ? 112.412 189.656 112.280 1.00 44.31 ? 13  GLN E CG  1 
ATOM   6687 C CD  . GLN E 5 13  ? 111.171 190.170 113.047 1.00 51.04 ? 13  GLN E CD  1 
ATOM   6688 O OE1 . GLN E 5 13  ? 110.996 189.816 114.212 1.00 50.53 ? 13  GLN E OE1 1 
ATOM   6689 N NE2 . GLN E 5 13  ? 110.308 190.971 112.409 1.00 49.81 ? 13  GLN E NE2 1 
ATOM   6690 N N   . PRO E 5 14  ? 116.541 188.558 113.051 1.00 40.85 ? 14  PRO E N   1 
ATOM   6691 C CA  . PRO E 5 14  ? 117.775 188.280 113.797 1.00 42.89 ? 14  PRO E CA  1 
ATOM   6692 C C   . PRO E 5 14  ? 117.506 188.118 115.286 1.00 47.56 ? 14  PRO E C   1 
ATOM   6693 O O   . PRO E 5 14  ? 116.611 188.749 115.852 1.00 50.03 ? 14  PRO E O   1 
ATOM   6694 C CB  . PRO E 5 14  ? 118.646 189.509 113.518 1.00 46.25 ? 14  PRO E CB  1 
ATOM   6695 C CG  . PRO E 5 14  ? 117.683 190.584 113.167 1.00 48.14 ? 14  PRO E CG  1 
ATOM   6696 C CD  . PRO E 5 14  ? 116.549 189.911 112.468 1.00 45.58 ? 14  PRO E CD  1 
ATOM   6697 N N   . GLY E 5 15  ? 118.303 187.263 115.922 1.00 42.99 ? 15  GLY E N   1 
ATOM   6698 C CA  . GLY E 5 15  ? 118.167 187.002 117.339 1.00 44.91 ? 15  GLY E CA  1 
ATOM   6699 C C   . GLY E 5 15  ? 117.076 186.024 117.715 1.00 44.32 ? 15  GLY E C   1 
ATOM   6700 O O   . GLY E 5 15  ? 116.866 185.791 118.912 1.00 45.02 ? 15  GLY E O   1 
ATOM   6701 N N   . GLY E 5 16  ? 116.379 185.442 116.745 1.00 41.44 ? 16  GLY E N   1 
ATOM   6702 C CA  . GLY E 5 16  ? 115.302 184.512 117.010 1.00 42.18 ? 16  GLY E CA  1 
ATOM   6703 C C   . GLY E 5 16  ? 115.802 183.094 117.175 1.00 43.91 ? 16  GLY E C   1 
ATOM   6704 O O   . GLY E 5 16  ? 116.937 182.847 117.591 1.00 42.66 ? 16  GLY E O   1 
ATOM   6705 N N   . SER E 5 17  ? 114.902 182.150 116.874 1.00 47.38 ? 17  SER E N   1 
ATOM   6706 C CA  . SER E 5 17  ? 115.234 180.710 117.007 1.00 44.80 ? 17  SER E CA  1 
ATOM   6707 C C   . SER E 5 17  ? 114.486 179.916 115.929 1.00 46.92 ? 17  SER E C   1 
ATOM   6708 O O   . SER E 5 17  ? 113.332 180.287 115.620 1.00 52.51 ? 17  SER E O   1 
ATOM   6709 C CB  . SER E 5 17  ? 114.896 180.206 118.387 1.00 44.59 ? 17  SER E CB  1 
ATOM   6710 O OG  . SER E 5 17  ? 115.109 178.804 118.482 1.00 42.94 ? 17  SER E OG  1 
ATOM   6711 N N   . ARG E 5 18  ? 115.113 178.874 115.383 1.00 43.25 ? 18  ARG E N   1 
ATOM   6712 C CA  . ARG E 5 18  ? 114.508 178.047 114.349 1.00 43.17 ? 18  ARG E CA  1 
ATOM   6713 C C   . ARG E 5 18  ? 115.056 176.634 114.496 1.00 42.80 ? 18  ARG E C   1 
ATOM   6714 O O   . ARG E 5 18  ? 116.195 176.432 114.923 1.00 48.77 ? 18  ARG E O   1 
ATOM   6715 C CB  . ARG E 5 18  ? 114.781 178.619 112.950 1.00 44.28 ? 18  ARG E CB  1 
ATOM   6716 C CG  . ARG E 5 18  ? 114.260 177.785 111.772 1.00 46.38 ? 18  ARG E CG  1 
ATOM   6717 C CD  . ARG E 5 18  ? 112.733 177.702 111.720 1.00 48.53 ? 18  ARG E CD  1 
ATOM   6718 N NE  . ARG E 5 18  ? 112.092 179.017 111.770 1.00 52.01 ? 18  ARG E NE  1 
ATOM   6719 C CZ  . ARG E 5 18  ? 111.239 179.520 110.881 1.00 52.37 ? 18  ARG E CZ  1 
ATOM   6720 N NH1 . ARG E 5 18  ? 110.858 178.848 109.804 1.00 48.80 ? 18  ARG E NH1 1 
ATOM   6721 N NH2 . ARG E 5 18  ? 110.748 180.740 111.078 1.00 50.17 ? 18  ARG E NH2 1 
ATOM   6722 N N   . LYS E 5 19  ? 114.223 175.661 114.130 1.00 35.04 ? 19  LYS E N   1 
ATOM   6723 C CA  . LYS E 5 19  ? 114.513 174.243 114.298 1.00 35.64 ? 19  LYS E CA  1 
ATOM   6724 C C   . LYS E 5 19  ? 114.505 173.590 112.925 1.00 38.08 ? 19  LYS E C   1 
ATOM   6725 O O   . LYS E 5 19  ? 113.494 173.658 112.220 1.00 43.00 ? 19  LYS E O   1 
ATOM   6726 C CB  . LYS E 5 19  ? 113.455 173.591 115.200 1.00 49.50 ? 19  LYS E CB  1 
ATOM   6727 C CG  . LYS E 5 19  ? 113.546 172.063 115.374 1.00 47.46 ? 19  LYS E CG  1 
ATOM   6728 C CD  . LYS E 5 19  ? 113.426 171.656 116.851 1.00 44.56 ? 19  LYS E CD  1 
ATOM   6729 C CE  . LYS E 5 19  ? 114.004 170.290 117.127 1.00 38.53 ? 19  LYS E CE  1 
ATOM   6730 N NZ  . LYS E 5 19  ? 114.023 170.007 118.588 1.00 43.23 ? 19  LYS E NZ  1 
ATOM   6731 N N   . LEU E 5 20  ? 115.619 172.966 112.544 1.00 34.49 ? 20  LEU E N   1 
ATOM   6732 C CA  . LEU E 5 20  ? 115.706 172.186 111.316 1.00 39.08 ? 20  LEU E CA  1 
ATOM   6733 C C   . LEU E 5 20  ? 115.702 170.704 111.654 1.00 40.99 ? 20  LEU E C   1 
ATOM   6734 O O   . LEU E 5 20  ? 116.474 170.253 112.503 1.00 40.15 ? 20  LEU E O   1 
ATOM   6735 C CB  . LEU E 5 20  ? 116.969 172.509 110.513 1.00 37.68 ? 20  LEU E CB  1 
ATOM   6736 C CG  . LEU E 5 20  ? 117.076 173.900 109.890 1.00 39.02 ? 20  LEU E CG  1 
ATOM   6737 C CD1 . LEU E 5 20  ? 118.455 174.086 109.287 1.00 39.82 ? 20  LEU E CD1 1 
ATOM   6738 C CD2 . LEU E 5 20  ? 115.994 174.134 108.851 1.00 42.49 ? 20  LEU E CD2 1 
ATOM   6739 N N   . SER E 5 21  ? 114.833 169.956 110.977 1.00 33.16 ? 21  SER E N   1 
ATOM   6740 C CA  . SER E 5 21  ? 114.668 168.525 111.190 1.00 26.81 ? 21  SER E CA  1 
ATOM   6741 C C   . SER E 5 21  ? 114.989 167.788 109.900 1.00 24.65 ? 21  SER E C   1 
ATOM   6742 O O   . SER E 5 21  ? 114.451 168.127 108.841 1.00 25.25 ? 21  SER E O   1 
ATOM   6743 C CB  . SER E 5 21  ? 113.242 168.204 111.646 1.00 38.26 ? 21  SER E CB  1 
ATOM   6744 O OG  . SER E 5 21  ? 113.070 166.814 111.850 1.00 42.33 ? 21  SER E OG  1 
ATOM   6745 N N   . CYS E 5 22  ? 115.868 166.793 109.992 1.00 21.06 ? 22  CYS E N   1 
ATOM   6746 C CA  . CYS E 5 22  ? 116.250 165.948 108.865 1.00 19.35 ? 22  CYS E CA  1 
ATOM   6747 C C   . CYS E 5 22  ? 115.753 164.533 109.119 1.00 28.51 ? 22  CYS E C   1 
ATOM   6748 O O   . CYS E 5 22  ? 116.240 163.860 110.034 1.00 33.74 ? 22  CYS E O   1 
ATOM   6749 C CB  . CYS E 5 22  ? 117.764 165.948 108.669 1.00 30.99 ? 22  CYS E CB  1 
ATOM   6750 S SG  . CYS E 5 22  ? 118.370 164.607 107.628 1.00 43.99 ? 22  CYS E SG  1 
ATOM   6751 N N   . SER E 5 23  ? 114.814 164.078 108.292 1.00 27.33 ? 23  SER E N   1 
ATOM   6752 C CA  . SER E 5 23  ? 114.168 162.783 108.456 1.00 29.45 ? 23  SER E CA  1 
ATOM   6753 C C   . SER E 5 23  ? 114.722 161.795 107.442 1.00 20.39 ? 23  SER E C   1 
ATOM   6754 O O   . SER E 5 23  ? 114.616 162.007 106.231 1.00 27.90 ? 23  SER E O   1 
ATOM   6755 C CB  . SER E 5 23  ? 112.651 162.903 108.291 1.00 29.15 ? 23  SER E CB  1 
ATOM   6756 O OG  . SER E 5 23  ? 112.303 163.124 106.937 1.00 34.33 ? 23  SER E OG  1 
ATOM   6757 N N   . ALA E 5 24  ? 115.298 160.710 107.947 1.00 18.60 ? 24  ALA E N   1 
ATOM   6758 C CA  . ALA E 5 24  ? 115.913 159.676 107.131 1.00 26.07 ? 24  ALA E CA  1 
ATOM   6759 C C   . ALA E 5 24  ? 114.929 158.540 106.897 1.00 35.96 ? 24  ALA E C   1 
ATOM   6760 O O   . ALA E 5 24  ? 114.200 158.133 107.806 1.00 49.37 ? 24  ALA E O   1 
ATOM   6761 C CB  . ALA E 5 24  ? 117.173 159.127 107.799 1.00 29.89 ? 24  ALA E CB  1 
ATOM   6762 N N   . SER E 5 25  ? 114.917 158.029 105.669 1.00 31.05 ? 25  SER E N   1 
ATOM   6763 C CA  . SER E 5 25  ? 114.005 156.952 105.299 1.00 35.14 ? 25  SER E CA  1 
ATOM   6764 C C   . SER E 5 25  ? 114.640 156.136 104.188 1.00 35.34 ? 25  SER E C   1 
ATOM   6765 O O   . SER E 5 25  ? 114.638 156.564 103.030 1.00 32.75 ? 25  SER E O   1 
ATOM   6766 C CB  . SER E 5 25  ? 112.650 157.508 104.853 1.00 36.13 ? 25  SER E CB  1 
ATOM   6767 O OG  . SER E 5 25  ? 112.760 158.214 103.631 1.00 37.34 ? 25  SER E OG  1 
ATOM   6768 N N   . GLY E 5 26  ? 115.171 154.966 104.542 1.00 32.88 ? 26  GLY E N   1 
ATOM   6769 C CA  . GLY E 5 26  ? 115.736 154.051 103.568 1.00 29.91 ? 26  GLY E CA  1 
ATOM   6770 C C   . GLY E 5 26  ? 117.036 153.392 103.982 1.00 25.21 ? 26  GLY E C   1 
ATOM   6771 O O   . GLY E 5 26  ? 117.617 152.643 103.192 1.00 27.04 ? 26  GLY E O   1 
ATOM   6772 N N   . PHE E 5 27  ? 117.511 153.647 105.200 1.00 27.18 ? 27  PHE E N   1 
ATOM   6773 C CA  . PHE E 5 27  ? 118.725 152.999 105.673 1.00 33.33 ? 27  PHE E CA  1 
ATOM   6774 C C   . PHE E 5 27  ? 118.713 152.911 107.191 1.00 34.27 ? 27  PHE E C   1 
ATOM   6775 O O   . PHE E 5 27  ? 117.904 153.547 107.870 1.00 38.32 ? 27  PHE E O   1 
ATOM   6776 C CB  . PHE E 5 27  ? 119.991 153.722 105.190 1.00 30.35 ? 27  PHE E CB  1 
ATOM   6777 C CG  . PHE E 5 27  ? 120.143 155.123 105.699 1.00 22.09 ? 27  PHE E CG  1 
ATOM   6778 C CD1 . PHE E 5 27  ? 119.475 156.174 105.105 1.00 26.46 ? 27  PHE E CD1 1 
ATOM   6779 C CD2 . PHE E 5 27  ? 120.982 155.388 106.763 1.00 20.67 ? 27  PHE E CD2 1 
ATOM   6780 C CE1 . PHE E 5 27  ? 119.633 157.457 105.573 1.00 24.27 ? 27  PHE E CE1 1 
ATOM   6781 C CE2 . PHE E 5 27  ? 121.138 156.668 107.234 1.00 26.21 ? 27  PHE E CE2 1 
ATOM   6782 C CZ  . PHE E 5 27  ? 120.465 157.702 106.639 1.00 25.51 ? 27  PHE E CZ  1 
ATOM   6783 N N   . ALA E 5 28  ? 119.627 152.095 107.714 1.00 24.14 ? 28  ALA E N   1 
ATOM   6784 C CA  . ALA E 5 28  ? 119.774 151.923 109.154 1.00 24.55 ? 28  ALA E CA  1 
ATOM   6785 C C   . ALA E 5 28  ? 120.328 153.209 109.750 1.00 27.21 ? 28  ALA E C   1 
ATOM   6786 O O   . ALA E 5 28  ? 121.530 153.477 109.664 1.00 30.77 ? 28  ALA E O   1 
ATOM   6787 C CB  . ALA E 5 28  ? 120.691 150.742 109.452 1.00 25.64 ? 28  ALA E CB  1 
ATOM   6788 N N   . PHE E 5 29  ? 119.453 153.998 110.369 1.00 25.10 ? 29  PHE E N   1 
ATOM   6789 C CA  . PHE E 5 29  ? 119.822 155.336 110.808 1.00 20.54 ? 29  PHE E CA  1 
ATOM   6790 C C   . PHE E 5 29  ? 120.670 155.319 112.072 1.00 15.89 ? 29  PHE E C   1 
ATOM   6791 O O   . PHE E 5 29  ? 121.532 156.185 112.242 1.00 23.88 ? 29  PHE E O   1 
ATOM   6792 C CB  . PHE E 5 29  ? 118.557 156.159 111.035 1.00 31.61 ? 29  PHE E CB  1 
ATOM   6793 C CG  . PHE E 5 29  ? 118.814 157.579 111.428 1.00 31.40 ? 29  PHE E CG  1 
ATOM   6794 C CD1 . PHE E 5 29  ? 119.106 158.527 110.470 1.00 28.52 ? 29  PHE E CD1 1 
ATOM   6795 C CD2 . PHE E 5 29  ? 118.735 157.972 112.750 1.00 31.45 ? 29  PHE E CD2 1 
ATOM   6796 C CE1 . PHE E 5 29  ? 119.329 159.833 110.822 1.00 22.53 ? 29  PHE E CE1 1 
ATOM   6797 C CE2 . PHE E 5 29  ? 118.956 159.280 113.105 1.00 29.55 ? 29  PHE E CE2 1 
ATOM   6798 C CZ  . PHE E 5 29  ? 119.255 160.210 112.139 1.00 27.23 ? 29  PHE E CZ  1 
ATOM   6799 N N   . SER E 5 30  ? 120.442 154.356 112.962 1.00 19.95 ? 30  SER E N   1 
ATOM   6800 C CA  . SER E 5 30  ? 121.158 154.308 114.230 1.00 26.99 ? 30  SER E CA  1 
ATOM   6801 C C   . SER E 5 30  ? 122.627 153.935 114.078 1.00 25.22 ? 30  SER E C   1 
ATOM   6802 O O   . SER E 5 30  ? 123.411 154.211 114.991 1.00 29.97 ? 30  SER E O   1 
ATOM   6803 C CB  . SER E 5 30  ? 120.479 153.313 115.173 1.00 29.02 ? 30  SER E CB  1 
ATOM   6804 O OG  . SER E 5 30  ? 121.214 153.162 116.374 1.00 34.52 ? 30  SER E OG  1 
ATOM   6805 N N   . SER E 5 31  ? 123.018 153.321 112.963 1.00 22.43 ? 31  SER E N   1 
ATOM   6806 C CA  . SER E 5 31  ? 124.387 152.863 112.769 1.00 28.59 ? 31  SER E CA  1 
ATOM   6807 C C   . SER E 5 31  ? 125.299 153.911 112.142 1.00 29.31 ? 31  SER E C   1 
ATOM   6808 O O   . SER E 5 31  ? 126.504 153.662 112.025 1.00 24.47 ? 31  SER E O   1 
ATOM   6809 C CB  . SER E 5 31  ? 124.395 151.606 111.894 1.00 23.82 ? 31  SER E CB  1 
ATOM   6810 O OG  . SER E 5 31  ? 124.063 150.458 112.654 1.00 24.14 ? 31  SER E OG  1 
ATOM   6811 N N   . PHE E 5 32  ? 124.768 155.068 111.752 1.00 24.69 ? 32  PHE E N   1 
ATOM   6812 C CA  . PHE E 5 32  ? 125.514 156.091 111.036 1.00 13.89 ? 32  PHE E CA  1 
ATOM   6813 C C   . PHE E 5 32  ? 125.720 157.315 111.915 1.00 19.09 ? 32  PHE E C   1 
ATOM   6814 O O   . PHE E 5 32  ? 124.842 157.695 112.694 1.00 30.84 ? 32  PHE E O   1 
ATOM   6815 C CB  . PHE E 5 32  ? 124.780 156.510 109.761 1.00 14.64 ? 32  PHE E CB  1 
ATOM   6816 C CG  . PHE E 5 32  ? 124.931 155.541 108.630 1.00 17.39 ? 32  PHE E CG  1 
ATOM   6817 C CD1 . PHE E 5 32  ? 124.305 154.312 108.667 1.00 24.58 ? 32  PHE E CD1 1 
ATOM   6818 C CD2 . PHE E 5 32  ? 125.698 155.859 107.529 1.00 22.88 ? 32  PHE E CD2 1 
ATOM   6819 C CE1 . PHE E 5 32  ? 124.442 153.422 107.630 1.00 21.59 ? 32  PHE E CE1 1 
ATOM   6820 C CE2 . PHE E 5 32  ? 125.839 154.971 106.489 1.00 23.35 ? 32  PHE E CE2 1 
ATOM   6821 C CZ  . PHE E 5 32  ? 125.210 153.752 106.539 1.00 21.83 ? 32  PHE E CZ  1 
ATOM   6822 N N   . GLY E 5 33  ? 126.890 157.928 111.779 1.00 19.48 ? 33  GLY E N   1 
ATOM   6823 C CA  . GLY E 5 33  ? 127.156 159.227 112.360 1.00 18.51 ? 33  GLY E CA  1 
ATOM   6824 C C   . GLY E 5 33  ? 126.796 160.312 111.364 1.00 20.18 ? 33  GLY E C   1 
ATOM   6825 O O   . GLY E 5 33  ? 127.213 160.275 110.210 1.00 43.93 ? 33  GLY E O   1 
ATOM   6826 N N   . MET E 5 34  ? 126.019 161.288 111.826 1.00 6.91  ? 34  MET E N   1 
ATOM   6827 C CA  . MET E 5 34  ? 125.444 162.312 110.968 1.00 16.89 ? 34  MET E CA  1 
ATOM   6828 C C   . MET E 5 34  ? 126.153 163.637 111.197 1.00 13.53 ? 34  MET E C   1 
ATOM   6829 O O   . MET E 5 34  ? 126.535 163.966 112.322 1.00 24.93 ? 34  MET E O   1 
ATOM   6830 C CB  . MET E 5 34  ? 123.948 162.489 111.230 1.00 25.09 ? 34  MET E CB  1 
ATOM   6831 C CG  . MET E 5 34  ? 123.122 161.220 111.142 1.00 32.08 ? 34  MET E CG  1 
ATOM   6832 S SD  . MET E 5 34  ? 123.076 160.534 109.481 1.00 31.73 ? 34  MET E SD  1 
ATOM   6833 C CE  . MET E 5 34  ? 121.804 161.548 108.734 1.00 26.40 ? 34  MET E CE  1 
ATOM   6834 N N   . HIS E 5 35  ? 126.317 164.391 110.114 1.00 19.62 ? 35  HIS E N   1 
ATOM   6835 C CA  . HIS E 5 35  ? 126.996 165.680 110.144 1.00 17.24 ? 35  HIS E CA  1 
ATOM   6836 C C   . HIS E 5 35  ? 126.005 166.797 109.840 1.00 18.00 ? 35  HIS E C   1 
ATOM   6837 O O   . HIS E 5 35  ? 126.391 167.924 109.531 1.00 8.49  ? 35  HIS E O   1 
ATOM   6838 C CB  . HIS E 5 35  ? 128.145 165.694 109.139 1.00 31.94 ? 35  HIS E CB  1 
ATOM   6839 C CG  . HIS E 5 35  ? 129.337 164.897 109.569 1.00 25.13 ? 35  HIS E CG  1 
ATOM   6840 N ND1 . HIS E 5 35  ? 129.450 163.546 109.331 1.00 20.81 ? 35  HIS E ND1 1 
ATOM   6841 C CD2 . HIS E 5 35  ? 130.474 165.262 110.205 1.00 24.00 ? 35  HIS E CD2 1 
ATOM   6842 C CE1 . HIS E 5 35  ? 130.600 163.112 109.811 1.00 20.38 ? 35  HIS E CE1 1 
ATOM   6843 N NE2 . HIS E 5 35  ? 131.241 164.133 110.346 1.00 22.27 ? 35  HIS E NE2 1 
ATOM   6844 N N   . VAL E 5 37  ? 126.649 170.378 107.704 1.00 6.40  ? 37  VAL E N   1 
ATOM   6845 C CA  . VAL E 5 37  ? 127.371 171.065 106.642 1.00 17.57 ? 37  VAL E CA  1 
ATOM   6846 C C   . VAL E 5 37  ? 126.449 172.069 105.970 1.00 11.95 ? 37  VAL E C   1 
ATOM   6847 O O   . VAL E 5 37  ? 125.414 171.688 105.434 1.00 33.19 ? 37  VAL E O   1 
ATOM   6848 C CB  . VAL E 5 37  ? 127.928 170.071 105.611 1.00 8.65  ? 37  VAL E CB  1 
ATOM   6849 C CG1 . VAL E 5 37  ? 128.594 170.818 104.470 1.00 12.34 ? 37  VAL E CG1 1 
ATOM   6850 C CG2 . VAL E 5 37  ? 128.898 169.098 106.269 1.00 16.77 ? 37  VAL E CG2 1 
ATOM   6851 N N   . ARG E 5 38  ? 126.829 173.346 105.998 1.00 8.26  ? 38  ARG E N   1 
ATOM   6852 C CA  . ARG E 5 38  ? 126.035 174.421 105.420 1.00 5.63  ? 38  ARG E CA  1 
ATOM   6853 C C   . ARG E 5 38  ? 126.785 175.043 104.253 1.00 22.28 ? 38  ARG E C   1 
ATOM   6854 O O   . ARG E 5 38  ? 127.995 174.865 104.099 1.00 43.43 ? 38  ARG E O   1 
ATOM   6855 C CB  . ARG E 5 38  ? 125.698 175.498 106.460 1.00 16.81 ? 38  ARG E CB  1 
ATOM   6856 C CG  . ARG E 5 38  ? 126.877 176.329 106.947 1.00 24.46 ? 38  ARG E CG  1 
ATOM   6857 C CD  . ARG E 5 38  ? 126.453 177.261 108.066 1.00 25.81 ? 38  ARG E CD  1 
ATOM   6858 N NE  . ARG E 5 38  ? 127.591 177.912 108.703 1.00 22.91 ? 38  ARG E NE  1 
ATOM   6859 C CZ  . ARG E 5 38  ? 127.504 178.784 109.699 1.00 24.42 ? 38  ARG E CZ  1 
ATOM   6860 N NH1 . ARG E 5 38  ? 126.336 179.149 110.205 1.00 26.63 ? 38  ARG E NH1 1 
ATOM   6861 N NH2 . ARG E 5 38  ? 128.618 179.304 110.203 1.00 32.58 ? 38  ARG E NH2 1 
ATOM   6862 N N   . GLN E 5 39  ? 126.044 175.779 103.429 1.00 22.23 ? 39  GLN E N   1 
ATOM   6863 C CA  . GLN E 5 39  ? 126.596 176.474 102.274 1.00 23.15 ? 39  GLN E CA  1 
ATOM   6864 C C   . GLN E 5 39  ? 125.971 177.855 102.180 1.00 25.39 ? 39  GLN E C   1 
ATOM   6865 O O   . GLN E 5 39  ? 124.749 177.980 102.057 1.00 38.75 ? 39  GLN E O   1 
ATOM   6866 C CB  . GLN E 5 39  ? 126.337 175.695 100.983 1.00 21.87 ? 39  GLN E CB  1 
ATOM   6867 C CG  . GLN E 5 39  ? 127.095 176.225 99.782  1.00 24.92 ? 39  GLN E CG  1 
ATOM   6868 C CD  . GLN E 5 39  ? 126.790 175.455 98.519  1.00 33.09 ? 39  GLN E CD  1 
ATOM   6869 O OE1 . GLN E 5 39  ? 125.902 174.605 98.495  1.00 29.40 ? 39  GLN E OE1 1 
ATOM   6870 N NE2 . GLN E 5 39  ? 127.525 175.751 97.455  1.00 32.61 ? 39  GLN E NE2 1 
ATOM   6871 N N   . ALA E 5 40  ? 126.809 178.886 102.224 1.00 25.27 ? 40  ALA E N   1 
ATOM   6872 C CA  . ALA E 5 40  ? 126.329 180.245 102.070 1.00 29.54 ? 40  ALA E CA  1 
ATOM   6873 C C   . ALA E 5 40  ? 125.800 180.452 100.651 1.00 34.55 ? 40  ALA E C   1 
ATOM   6874 O O   . ALA E 5 40  ? 125.986 179.597 99.783  1.00 39.88 ? 40  ALA E O   1 
ATOM   6875 C CB  . ALA E 5 40  ? 127.450 181.233 102.380 1.00 37.60 ? 40  ALA E CB  1 
ATOM   6876 N N   . PRO E 5 41  ? 125.106 181.570 100.395 1.00 37.86 ? 41  PRO E N   1 
ATOM   6877 C CA  . PRO E 5 41  ? 124.567 181.786 99.039  1.00 43.19 ? 41  PRO E CA  1 
ATOM   6878 C C   . PRO E 5 41  ? 125.620 181.800 97.942  1.00 45.86 ? 41  PRO E C   1 
ATOM   6879 O O   . PRO E 5 41  ? 125.358 181.296 96.843  1.00 43.73 ? 41  PRO E O   1 
ATOM   6880 C CB  . PRO E 5 41  ? 123.863 183.145 99.161  1.00 43.69 ? 41  PRO E CB  1 
ATOM   6881 C CG  . PRO E 5 41  ? 123.506 183.256 100.588 1.00 41.08 ? 41  PRO E CG  1 
ATOM   6882 C CD  . PRO E 5 41  ? 124.614 182.589 101.341 1.00 34.43 ? 41  PRO E CD  1 
ATOM   6883 N N   . GLU E 5 42  ? 126.801 182.357 98.206  1.00 51.48 ? 42  GLU E N   1 
ATOM   6884 C CA  . GLU E 5 42  ? 127.861 182.504 97.210  1.00 51.59 ? 42  GLU E CA  1 
ATOM   6885 C C   . GLU E 5 42  ? 129.212 182.125 97.805  1.00 50.01 ? 42  GLU E C   1 
ATOM   6886 O O   . GLU E 5 42  ? 130.206 182.838 97.658  1.00 52.61 ? 42  GLU E O   1 
ATOM   6887 C CB  . GLU E 5 42  ? 127.897 183.932 96.670  1.00 53.35 ? 42  GLU E CB  1 
ATOM   6888 C CG  . GLU E 5 42  ? 126.577 184.428 96.081  1.00 53.88 ? 42  GLU E CG  1 
ATOM   6889 C CD  . GLU E 5 42  ? 126.043 183.536 94.977  1.00 55.19 ? 42  GLU E CD  1 
ATOM   6890 O OE1 . GLU E 5 42  ? 126.842 183.102 94.121  1.00 52.43 ? 42  GLU E OE1 1 
ATOM   6891 O OE2 . GLU E 5 42  ? 124.823 183.268 94.965  1.00 51.56 ? 42  GLU E OE2 1 
ATOM   6892 N N   . LYS E 5 43  ? 129.263 180.987 98.495  1.00 32.38 ? 43  LYS E N   1 
ATOM   6893 C CA  . LYS E 5 43  ? 130.500 180.513 99.097  1.00 33.33 ? 43  LYS E CA  1 
ATOM   6894 C C   . LYS E 5 43  ? 130.443 178.993 99.188  1.00 32.45 ? 43  LYS E C   1 
ATOM   6895 O O   . LYS E 5 43  ? 129.372 178.385 99.131  1.00 35.71 ? 43  LYS E O   1 
ATOM   6896 C CB  . LYS E 5 43  ? 130.739 181.206 100.456 1.00 26.67 ? 43  LYS E CB  1 
ATOM   6897 C CG  . LYS E 5 43  ? 131.138 180.323 101.653 1.00 31.99 ? 43  LYS E CG  1 
ATOM   6898 C CD  . LYS E 5 43  ? 131.138 181.109 102.954 1.00 33.91 ? 43  LYS E CD  1 
ATOM   6899 C CE  . LYS E 5 43  ? 131.140 180.181 104.161 1.00 32.40 ? 43  LYS E CE  1 
ATOM   6900 N NZ  . LYS E 5 43  ? 129.814 179.543 104.394 1.00 32.67 ? 43  LYS E NZ  1 
ATOM   6901 N N   . GLY E 5 44  ? 131.619 178.382 99.319  1.00 34.52 ? 44  GLY E N   1 
ATOM   6902 C CA  . GLY E 5 44  ? 131.727 176.943 99.393  1.00 28.10 ? 44  GLY E CA  1 
ATOM   6903 C C   . GLY E 5 44  ? 131.193 176.387 100.696 1.00 24.32 ? 44  GLY E C   1 
ATOM   6904 O O   . GLY E 5 44  ? 130.763 177.109 101.594 1.00 29.03 ? 44  GLY E O   1 
ATOM   6905 N N   . LEU E 5 45  ? 131.224 175.062 100.791 1.00 20.39 ? 45  LEU E N   1 
ATOM   6906 C CA  . LEU E 5 45  ? 130.661 174.379 101.945 1.00 22.68 ? 45  LEU E CA  1 
ATOM   6907 C C   . LEU E 5 45  ? 131.464 174.688 103.202 1.00 20.18 ? 45  LEU E C   1 
ATOM   6908 O O   . LEU E 5 45  ? 132.690 174.806 103.170 1.00 30.20 ? 45  LEU E O   1 
ATOM   6909 C CB  . LEU E 5 45  ? 130.629 172.869 101.709 1.00 26.94 ? 45  LEU E CB  1 
ATOM   6910 C CG  . LEU E 5 45  ? 129.976 172.389 100.410 1.00 32.77 ? 45  LEU E CG  1 
ATOM   6911 C CD1 . LEU E 5 45  ? 130.111 170.885 100.267 1.00 28.72 ? 45  LEU E CD1 1 
ATOM   6912 C CD2 . LEU E 5 45  ? 128.518 172.801 100.354 1.00 20.19 ? 45  LEU E CD2 1 
ATOM   6913 N N   . GLU E 5 46  ? 130.749 174.828 104.318 1.00 14.21 ? 46  GLU E N   1 
ATOM   6914 C CA  . GLU E 5 46  ? 131.339 175.076 105.624 1.00 10.23 ? 46  GLU E CA  1 
ATOM   6915 C C   . GLU E 5 46  ? 130.739 174.114 106.635 1.00 17.02 ? 46  GLU E C   1 
ATOM   6916 O O   . GLU E 5 46  ? 129.516 174.034 106.776 1.00 34.00 ? 46  GLU E O   1 
ATOM   6917 C CB  . GLU E 5 46  ? 131.102 176.518 106.077 1.00 7.30  ? 46  GLU E CB  1 
ATOM   6918 N N   . TRP E 5 47  ? 131.602 173.390 107.340 1.00 17.96 ? 47  TRP E N   1 
ATOM   6919 C CA  . TRP E 5 47  ? 131.143 172.439 108.340 1.00 14.13 ? 47  TRP E CA  1 
ATOM   6920 C C   . TRP E 5 47  ? 130.455 173.164 109.491 1.00 25.09 ? 47  TRP E C   1 
ATOM   6921 O O   . TRP E 5 47  ? 130.823 174.284 109.853 1.00 41.24 ? 47  TRP E O   1 
ATOM   6922 C CB  . TRP E 5 47  ? 132.321 171.621 108.858 1.00 16.77 ? 47  TRP E CB  1 
ATOM   6923 C CG  . TRP E 5 47  ? 131.932 170.546 109.804 1.00 18.46 ? 47  TRP E CG  1 
ATOM   6924 C CD1 . TRP E 5 47  ? 131.106 169.500 109.552 1.00 17.31 ? 47  TRP E CD1 1 
ATOM   6925 C CD2 . TRP E 5 47  ? 132.362 170.402 111.163 1.00 29.37 ? 47  TRP E CD2 1 
ATOM   6926 N NE1 . TRP E 5 47  ? 130.987 168.713 110.667 1.00 23.51 ? 47  TRP E NE1 1 
ATOM   6927 C CE2 . TRP E 5 47  ? 131.751 169.245 111.671 1.00 24.19 ? 47  TRP E CE2 1 
ATOM   6928 C CE3 . TRP E 5 47  ? 133.205 171.141 111.998 1.00 24.78 ? 47  TRP E CE3 1 
ATOM   6929 C CZ2 . TRP E 5 47  ? 131.953 168.807 112.974 1.00 19.36 ? 47  TRP E CZ2 1 
ATOM   6930 C CZ3 . TRP E 5 47  ? 133.400 170.706 113.291 1.00 13.55 ? 47  TRP E CZ3 1 
ATOM   6931 C CH2 . TRP E 5 47  ? 132.782 169.549 113.766 1.00 8.74  ? 47  TRP E CH2 1 
ATOM   6932 N N   . VAL E 5 48  ? 129.446 172.508 110.070 1.00 17.22 ? 48  VAL E N   1 
ATOM   6933 C CA  . VAL E 5 48  ? 128.620 173.103 111.119 1.00 18.63 ? 48  VAL E CA  1 
ATOM   6934 C C   . VAL E 5 48  ? 128.725 172.296 112.405 1.00 28.27 ? 48  VAL E C   1 
ATOM   6935 O O   . VAL E 5 48  ? 129.054 172.844 113.462 1.00 49.80 ? 48  VAL E O   1 
ATOM   6936 C CB  . VAL E 5 48  ? 127.155 173.219 110.664 1.00 21.39 ? 48  VAL E CB  1 
ATOM   6937 C CG1 . VAL E 5 48  ? 126.252 173.604 111.830 1.00 26.95 ? 48  VAL E CG1 1 
ATOM   6938 C CG2 . VAL E 5 48  ? 127.035 174.234 109.549 1.00 26.41 ? 48  VAL E CG2 1 
ATOM   6939 N N   . ALA E 5 49  ? 128.441 170.997 112.338 1.00 10.01 ? 49  ALA E N   1 
ATOM   6940 C CA  . ALA E 5 49  ? 128.372 170.194 113.551 1.00 10.85 ? 49  ALA E CA  1 
ATOM   6941 C C   . ALA E 5 49  ? 128.441 168.720 113.188 1.00 9.54  ? 49  ALA E C   1 
ATOM   6942 O O   . ALA E 5 49  ? 128.508 168.356 112.013 1.00 34.26 ? 49  ALA E O   1 
ATOM   6943 C CB  . ALA E 5 49  ? 127.094 170.499 114.332 1.00 15.31 ? 49  ALA E CB  1 
ATOM   6944 N N   . TYR E 5 50  ? 128.427 167.873 114.218 1.00 0.68  ? 50  TYR E N   1 
ATOM   6945 C CA  . TYR E 5 50  ? 128.503 166.431 114.035 1.00 9.24  ? 50  TYR E CA  1 
ATOM   6946 C C   . TYR E 5 50  ? 127.911 165.724 115.244 1.00 16.58 ? 50  TYR E C   1 
ATOM   6947 O O   . TYR E 5 50  ? 128.225 166.068 116.385 1.00 39.34 ? 50  TYR E O   1 
ATOM   6948 C CB  . TYR E 5 50  ? 129.949 165.980 113.829 1.00 15.58 ? 50  TYR E CB  1 
ATOM   6949 C CG  . TYR E 5 50  ? 130.196 164.509 114.065 1.00 5.06  ? 50  TYR E CG  1 
ATOM   6950 C CD1 . TYR E 5 50  ? 129.835 163.567 113.118 1.00 24.30 ? 50  TYR E CD1 1 
ATOM   6951 C CD2 . TYR E 5 50  ? 130.809 164.064 115.222 1.00 11.92 ? 50  TYR E CD2 1 
ATOM   6952 C CE1 . TYR E 5 50  ? 130.069 162.224 113.321 1.00 26.46 ? 50  TYR E CE1 1 
ATOM   6953 C CE2 . TYR E 5 50  ? 131.048 162.723 115.433 1.00 9.19  ? 50  TYR E CE2 1 
ATOM   6954 C CZ  . TYR E 5 50  ? 130.676 161.809 114.480 1.00 9.07  ? 50  TYR E CZ  1 
ATOM   6955 O OH  . TYR E 5 50  ? 130.913 160.474 114.692 1.00 19.11 ? 50  TYR E OH  1 
ATOM   6956 N N   . ILE E 5 51  ? 127.056 164.737 114.981 1.00 24.05 ? 51  ILE E N   1 
ATOM   6957 C CA  . ILE E 5 51  ? 126.435 163.907 116.007 1.00 18.13 ? 51  ILE E CA  1 
ATOM   6958 C C   . ILE E 5 51  ? 126.780 162.456 115.695 1.00 29.95 ? 51  ILE E C   1 
ATOM   6959 O O   . ILE E 5 51  ? 126.635 162.012 114.551 1.00 45.66 ? 51  ILE E O   1 
ATOM   6960 C CB  . ILE E 5 51  ? 124.909 164.137 116.074 1.00 22.93 ? 51  ILE E CB  1 
ATOM   6961 C CG1 . ILE E 5 51  ? 124.223 163.182 117.058 1.00 32.32 ? 51  ILE E CG1 1 
ATOM   6962 C CG2 . ILE E 5 51  ? 124.257 164.007 114.705 1.00 35.74 ? 51  ILE E CG2 1 
ATOM   6963 C CD1 . ILE E 5 51  ? 124.708 163.328 118.466 1.00 33.04 ? 51  ILE E CD1 1 
ATOM   6964 N N   . SER E 5 52  ? 127.250 161.727 116.704 1.00 14.95 ? 52  SER E N   1 
ATOM   6965 C CA  . SER E 5 52  ? 127.818 160.403 116.501 1.00 22.90 ? 52  SER E CA  1 
ATOM   6966 C C   . SER E 5 52  ? 126.728 159.333 116.477 1.00 23.13 ? 52  SER E C   1 
ATOM   6967 O O   . SER E 5 52  ? 125.533 159.623 116.396 1.00 34.15 ? 52  SER E O   1 
ATOM   6968 C CB  . SER E 5 52  ? 128.847 160.101 117.586 1.00 26.05 ? 52  SER E CB  1 
ATOM   6969 O OG  . SER E 5 52  ? 129.401 158.811 117.407 1.00 32.71 ? 52  SER E OG  1 
ATOM   6970 N N   . SER E 5 53  ? 127.154 158.071 116.528 1.00 24.86 ? 53  SER E N   1 
ATOM   6971 C CA  . SER E 5 53  ? 126.240 156.937 116.593 1.00 33.55 ? 53  SER E CA  1 
ATOM   6972 C C   . SER E 5 53  ? 125.781 156.732 118.031 1.00 36.35 ? 53  SER E C   1 
ATOM   6973 O O   . SER E 5 53  ? 126.603 156.664 118.950 1.00 37.81 ? 53  SER E O   1 
ATOM   6974 C CB  . SER E 5 53  ? 126.912 155.668 116.066 1.00 35.57 ? 53  SER E CB  1 
ATOM   6975 O OG  . SER E 5 53  ? 127.887 155.188 116.974 1.00 34.19 ? 53  SER E OG  1 
ATOM   6976 N N   . GLY E 5 54  ? 124.469 156.631 118.221 1.00 37.14 ? 54  GLY E N   1 
ATOM   6977 C CA  . GLY E 5 54  ? 123.910 156.540 119.553 1.00 41.18 ? 54  GLY E CA  1 
ATOM   6978 C C   . GLY E 5 54  ? 124.042 157.795 120.385 1.00 36.37 ? 54  GLY E C   1 
ATOM   6979 O O   . GLY E 5 54  ? 123.867 157.727 121.606 1.00 38.56 ? 54  GLY E O   1 
ATOM   6980 N N   . SER E 5 55  ? 124.343 158.937 119.764 1.00 31.51 ? 55  SER E N   1 
ATOM   6981 C CA  . SER E 5 55  ? 124.473 160.214 120.466 1.00 29.68 ? 55  SER E CA  1 
ATOM   6982 C C   . SER E 5 55  ? 125.550 160.148 121.544 1.00 30.40 ? 55  SER E C   1 
ATOM   6983 O O   . SER E 5 55  ? 125.434 160.769 122.601 1.00 37.14 ? 55  SER E O   1 
ATOM   6984 C CB  . SER E 5 55  ? 123.136 160.649 121.066 1.00 34.58 ? 55  SER E CB  1 
ATOM   6985 O OG  . SER E 5 55  ? 122.134 160.713 120.070 1.00 28.34 ? 55  SER E OG  1 
ATOM   6986 N N   . GLY E 5 56  ? 126.606 159.389 121.277 1.00 26.01 ? 56  GLY E N   1 
ATOM   6987 C CA  . GLY E 5 56  ? 127.700 159.235 122.207 1.00 29.12 ? 56  GLY E CA  1 
ATOM   6988 C C   . GLY E 5 56  ? 128.777 160.293 122.128 1.00 32.34 ? 56  GLY E C   1 
ATOM   6989 O O   . GLY E 5 56  ? 129.655 160.322 122.995 1.00 30.62 ? 56  GLY E O   1 
ATOM   6990 N N   . THR E 5 57  ? 128.743 161.164 121.120 1.00 32.19 ? 57  THR E N   1 
ATOM   6991 C CA  . THR E 5 57  ? 129.783 162.170 120.941 1.00 24.64 ? 57  THR E CA  1 
ATOM   6992 C C   . THR E 5 57  ? 129.254 163.271 120.037 1.00 19.41 ? 57  THR E C   1 
ATOM   6993 O O   . THR E 5 57  ? 128.630 162.985 119.012 1.00 32.83 ? 57  THR E O   1 
ATOM   6994 C CB  . THR E 5 57  ? 131.051 161.557 120.340 1.00 22.69 ? 57  THR E CB  1 
ATOM   6995 O OG1 . THR E 5 57  ? 131.612 160.610 121.256 1.00 30.26 ? 57  THR E OG1 1 
ATOM   6996 C CG2 . THR E 5 57  ? 132.071 162.634 120.041 1.00 22.24 ? 57  THR E CG2 1 
ATOM   6997 N N   . ILE E 5 58  ? 129.512 164.520 120.418 1.00 15.00 ? 58  ILE E N   1 
ATOM   6998 C CA  . ILE E 5 58  ? 129.037 165.693 119.697 1.00 17.18 ? 58  ILE E CA  1 
ATOM   6999 C C   . ILE E 5 58  ? 130.218 166.645 119.541 1.00 27.22 ? 58  ILE E C   1 
ATOM   7000 O O   . ILE E 5 58  ? 130.949 166.898 120.504 1.00 38.63 ? 58  ILE E O   1 
ATOM   7001 C CB  . ILE E 5 58  ? 127.868 166.374 120.448 1.00 20.21 ? 58  ILE E CB  1 
ATOM   7002 C CG1 . ILE E 5 58  ? 126.758 165.346 120.742 1.00 27.96 ? 58  ILE E CG1 1 
ATOM   7003 C CG2 . ILE E 5 58  ? 127.295 167.527 119.614 1.00 15.71 ? 58  ILE E CG2 1 
ATOM   7004 C CD1 . ILE E 5 58  ? 125.312 165.893 120.883 1.00 27.86 ? 58  ILE E CD1 1 
ATOM   7005 N N   . TYR E 5 59  ? 130.406 167.166 118.326 1.00 20.58 ? 59  TYR E N   1 
ATOM   7006 C CA  . TYR E 5 59  ? 131.360 168.235 118.057 1.00 20.78 ? 59  TYR E CA  1 
ATOM   7007 C C   . TYR E 5 59  ? 130.664 169.367 117.316 1.00 22.13 ? 59  TYR E C   1 
ATOM   7008 O O   . TYR E 5 59  ? 129.699 169.144 116.582 1.00 30.45 ? 59  TYR E O   1 
ATOM   7009 C CB  . TYR E 5 59  ? 132.556 167.768 117.220 1.00 21.00 ? 59  TYR E CB  1 
ATOM   7010 C CG  . TYR E 5 59  ? 133.410 166.713 117.871 1.00 25.06 ? 59  TYR E CG  1 
ATOM   7011 C CD1 . TYR E 5 59  ? 134.347 167.048 118.836 1.00 33.74 ? 59  TYR E CD1 1 
ATOM   7012 C CD2 . TYR E 5 59  ? 133.312 165.388 117.488 1.00 22.46 ? 59  TYR E CD2 1 
ATOM   7013 C CE1 . TYR E 5 59  ? 135.138 166.080 119.425 1.00 35.50 ? 59  TYR E CE1 1 
ATOM   7014 C CE2 . TYR E 5 59  ? 134.098 164.419 118.063 1.00 23.44 ? 59  TYR E CE2 1 
ATOM   7015 C CZ  . TYR E 5 59  ? 135.008 164.766 119.030 1.00 32.17 ? 59  TYR E CZ  1 
ATOM   7016 O OH  . TYR E 5 59  ? 135.787 163.788 119.598 1.00 32.77 ? 59  TYR E OH  1 
ATOM   7017 N N   . TYR E 5 60  ? 131.167 170.585 117.516 1.00 21.18 ? 60  TYR E N   1 
ATOM   7018 C CA  . TYR E 5 60  ? 130.688 171.764 116.811 1.00 16.21 ? 60  TYR E CA  1 
ATOM   7019 C C   . TYR E 5 60  ? 131.870 172.563 116.289 1.00 22.54 ? 60  TYR E C   1 
ATOM   7020 O O   . TYR E 5 60  ? 132.979 172.496 116.823 1.00 36.02 ? 60  TYR E O   1 
ATOM   7021 C CB  . TYR E 5 60  ? 129.848 172.689 117.699 1.00 26.05 ? 60  TYR E CB  1 
ATOM   7022 C CG  . TYR E 5 60  ? 128.559 172.097 118.181 1.00 28.13 ? 60  TYR E CG  1 
ATOM   7023 C CD1 . TYR E 5 60  ? 128.525 171.322 119.324 1.00 29.24 ? 60  TYR E CD1 1 
ATOM   7024 C CD2 . TYR E 5 60  ? 127.379 172.286 117.481 1.00 26.42 ? 60  TYR E CD2 1 
ATOM   7025 C CE1 . TYR E 5 60  ? 127.356 170.789 119.777 1.00 28.43 ? 60  TYR E CE1 1 
ATOM   7026 C CE2 . TYR E 5 60  ? 126.203 171.737 117.921 1.00 26.40 ? 60  TYR E CE2 1 
ATOM   7027 C CZ  . TYR E 5 60  ? 126.200 170.982 119.068 1.00 32.80 ? 60  TYR E CZ  1 
ATOM   7028 O OH  . TYR E 5 60  ? 125.033 170.422 119.521 1.00 35.04 ? 60  TYR E OH  1 
ATOM   7029 N N   . ALA E 5 61  ? 131.615 173.329 115.235 1.00 6.09  ? 61  ALA E N   1 
ATOM   7030 C CA  . ALA E 5 61  ? 132.565 174.341 114.817 1.00 22.22 ? 61  ALA E CA  1 
ATOM   7031 C C   . ALA E 5 61  ? 132.546 175.495 115.814 1.00 29.52 ? 61  ALA E C   1 
ATOM   7032 O O   . ALA E 5 61  ? 131.556 175.728 116.511 1.00 39.19 ? 61  ALA E O   1 
ATOM   7033 C CB  . ALA E 5 61  ? 132.238 174.844 113.412 1.00 20.56 ? 61  ALA E CB  1 
ATOM   7034 N N   . ASP E 5 62  ? 133.668 176.212 115.890 1.00 22.15 ? 62  ASP E N   1 
ATOM   7035 C CA  . ASP E 5 62  ? 133.752 177.329 116.827 1.00 24.05 ? 62  ASP E CA  1 
ATOM   7036 C C   . ASP E 5 62  ? 132.751 178.430 116.492 1.00 27.45 ? 62  ASP E C   1 
ATOM   7037 O O   . ASP E 5 62  ? 132.289 179.140 117.392 1.00 28.81 ? 62  ASP E O   1 
ATOM   7038 C CB  . ASP E 5 62  ? 135.177 177.893 116.862 1.00 30.40 ? 62  ASP E CB  1 
ATOM   7039 C CG  . ASP E 5 62  ? 135.705 178.271 115.484 1.00 33.82 ? 62  ASP E CG  1 
ATOM   7040 O OD1 . ASP E 5 62  ? 134.903 178.401 114.536 1.00 35.57 ? 62  ASP E OD1 1 
ATOM   7041 O OD2 . ASP E 5 62  ? 136.935 178.442 115.351 1.00 28.45 ? 62  ASP E OD2 1 
ATOM   7042 N N   . THR E 5 63  ? 132.399 178.583 115.213 1.00 23.05 ? 63  THR E N   1 
ATOM   7043 C CA  . THR E 5 63  ? 131.478 179.645 114.822 1.00 23.98 ? 63  THR E CA  1 
ATOM   7044 C C   . THR E 5 63  ? 130.075 179.420 115.375 1.00 33.29 ? 63  THR E C   1 
ATOM   7045 O O   . THR E 5 63  ? 129.331 180.388 115.569 1.00 40.56 ? 63  THR E O   1 
ATOM   7046 C CB  . THR E 5 63  ? 131.425 179.757 113.298 1.00 28.30 ? 63  THR E CB  1 
ATOM   7047 O OG1 . THR E 5 63  ? 132.741 179.999 112.787 1.00 35.58 ? 63  THR E OG1 1 
ATOM   7048 C CG2 . THR E 5 63  ? 130.507 180.893 112.872 1.00 29.35 ? 63  THR E CG2 1 
ATOM   7049 N N   . VAL E 5 64  ? 129.701 178.167 115.637 1.00 32.84 ? 64  VAL E N   1 
ATOM   7050 C CA  . VAL E 5 64  ? 128.354 177.800 116.057 1.00 26.80 ? 64  VAL E CA  1 
ATOM   7051 C C   . VAL E 5 64  ? 128.362 177.090 117.409 1.00 29.37 ? 64  VAL E C   1 
ATOM   7052 O O   . VAL E 5 64  ? 127.492 176.274 117.681 1.00 28.51 ? 64  VAL E O   1 
ATOM   7053 C CB  . VAL E 5 64  ? 127.659 176.932 114.991 1.00 25.93 ? 64  VAL E CB  1 
ATOM   7054 C CG1 . VAL E 5 64  ? 127.606 177.661 113.660 1.00 32.28 ? 64  VAL E CG1 1 
ATOM   7055 C CG2 . VAL E 5 64  ? 128.348 175.576 114.851 1.00 29.77 ? 64  VAL E CG2 1 
ATOM   7056 N N   . LYS E 5 65  ? 129.332 177.399 118.262 1.00 35.01 ? 65  LYS E N   1 
ATOM   7057 C CA  . LYS E 5 65  ? 129.437 176.774 119.572 1.00 37.81 ? 65  LYS E CA  1 
ATOM   7058 C C   . LYS E 5 65  ? 128.578 177.535 120.573 1.00 43.75 ? 65  LYS E C   1 
ATOM   7059 O O   . LYS E 5 65  ? 128.592 178.770 120.602 1.00 43.60 ? 65  LYS E O   1 
ATOM   7060 C CB  . LYS E 5 65  ? 130.899 176.743 120.029 1.00 35.25 ? 65  LYS E CB  1 
ATOM   7061 C CG  . LYS E 5 65  ? 131.149 176.262 121.470 1.00 38.12 ? 65  LYS E CG  1 
ATOM   7062 C CD  . LYS E 5 65  ? 130.687 174.825 121.722 1.00 36.74 ? 65  LYS E CD  1 
ATOM   7063 C CE  . LYS E 5 65  ? 131.596 173.797 121.064 1.00 36.13 ? 65  LYS E CE  1 
ATOM   7064 N NZ  . LYS E 5 65  ? 132.985 173.829 121.598 1.00 39.75 ? 65  LYS E NZ  1 
ATOM   7065 N N   . GLY E 5 66  ? 127.832 176.794 121.391 1.00 47.57 ? 66  GLY E N   1 
ATOM   7066 C CA  . GLY E 5 66  ? 127.111 177.350 122.512 1.00 48.97 ? 66  GLY E CA  1 
ATOM   7067 C C   . GLY E 5 66  ? 125.662 177.694 122.239 1.00 54.61 ? 66  GLY E C   1 
ATOM   7068 O O   . GLY E 5 66  ? 124.893 177.846 123.197 1.00 53.91 ? 66  GLY E O   1 
ATOM   7069 N N   . ARG E 5 67  ? 125.265 177.818 120.966 1.00 44.29 ? 67  ARG E N   1 
ATOM   7070 C CA  . ARG E 5 67  ? 123.904 178.199 120.604 1.00 43.61 ? 67  ARG E CA  1 
ATOM   7071 C C   . ARG E 5 67  ? 123.253 177.234 119.617 1.00 42.12 ? 67  ARG E C   1 
ATOM   7072 O O   . ARG E 5 67  ? 122.054 177.371 119.346 1.00 43.06 ? 67  ARG E O   1 
ATOM   7073 C CB  . ARG E 5 67  ? 123.883 179.619 120.026 1.00 37.87 ? 67  ARG E CB  1 
ATOM   7074 C CG  . ARG E 5 67  ? 124.564 179.771 118.681 1.00 35.17 ? 67  ARG E CG  1 
ATOM   7075 C CD  . ARG E 5 67  ? 125.324 181.084 118.581 1.00 36.43 ? 67  ARG E CD  1 
ATOM   7076 N NE  . ARG E 5 67  ? 126.183 181.131 117.405 1.00 40.29 ? 67  ARG E NE  1 
ATOM   7077 C CZ  . ARG E 5 67  ? 125.762 181.350 116.165 1.00 42.45 ? 67  ARG E CZ  1 
ATOM   7078 N NH1 . ARG E 5 67  ? 124.482 181.545 115.887 1.00 44.93 ? 67  ARG E NH1 1 
ATOM   7079 N NH2 . ARG E 5 67  ? 126.650 181.375 115.176 1.00 38.33 ? 67  ARG E NH2 1 
ATOM   7080 N N   . PHE E 5 68  ? 124.001 176.269 119.076 1.00 32.53 ? 68  PHE E N   1 
ATOM   7081 C CA  . PHE E 5 68  ? 123.454 175.214 118.231 1.00 32.00 ? 68  PHE E CA  1 
ATOM   7082 C C   . PHE E 5 68  ? 123.439 173.918 119.026 1.00 31.48 ? 68  PHE E C   1 
ATOM   7083 O O   . PHE E 5 68  ? 124.446 173.552 119.640 1.00 33.54 ? 68  PHE E O   1 
ATOM   7084 C CB  . PHE E 5 68  ? 124.280 175.009 116.949 1.00 39.68 ? 68  PHE E CB  1 
ATOM   7085 C CG  . PHE E 5 68  ? 124.012 176.018 115.853 1.00 35.11 ? 68  PHE E CG  1 
ATOM   7086 C CD1 . PHE E 5 68  ? 123.521 177.284 116.128 1.00 31.56 ? 68  PHE E CD1 1 
ATOM   7087 C CD2 . PHE E 5 68  ? 124.257 175.682 114.533 1.00 32.18 ? 68  PHE E CD2 1 
ATOM   7088 C CE1 . PHE E 5 68  ? 123.294 178.189 115.110 1.00 31.82 ? 68  PHE E CE1 1 
ATOM   7089 C CE2 . PHE E 5 68  ? 124.030 176.583 113.517 1.00 27.26 ? 68  PHE E CE2 1 
ATOM   7090 C CZ  . PHE E 5 68  ? 123.546 177.835 113.804 1.00 25.06 ? 68  PHE E CZ  1 
ATOM   7091 N N   . THR E 5 69  ? 122.298 173.228 119.017 1.00 25.69 ? 69  THR E N   1 
ATOM   7092 C CA  . THR E 5 69  ? 122.130 171.965 119.726 1.00 29.22 ? 69  THR E CA  1 
ATOM   7093 C C   . THR E 5 69  ? 121.547 170.923 118.783 1.00 32.42 ? 69  THR E C   1 
ATOM   7094 O O   . THR E 5 69  ? 120.738 171.249 117.910 1.00 30.92 ? 69  THR E O   1 
ATOM   7095 C CB  . THR E 5 69  ? 121.224 172.120 120.951 1.00 37.03 ? 69  THR E CB  1 
ATOM   7096 O OG1 . THR E 5 69  ? 120.037 172.836 120.590 1.00 43.58 ? 69  THR E OG1 1 
ATOM   7097 C CG2 . THR E 5 69  ? 121.951 172.865 122.061 1.00 35.02 ? 69  THR E CG2 1 
ATOM   7098 N N   . ILE E 5 70  ? 121.959 169.668 118.973 1.00 39.27 ? 70  ILE E N   1 
ATOM   7099 C CA  . ILE E 5 70  ? 121.569 168.552 118.116 1.00 34.04 ? 70  ILE E CA  1 
ATOM   7100 C C   . ILE E 5 70  ? 121.084 167.404 118.988 1.00 31.56 ? 70  ILE E C   1 
ATOM   7101 O O   . ILE E 5 70  ? 121.711 167.072 120.000 1.00 42.27 ? 70  ILE E O   1 
ATOM   7102 C CB  . ILE E 5 70  ? 122.729 168.094 117.214 1.00 30.10 ? 70  ILE E CB  1 
ATOM   7103 C CG1 . ILE E 5 70  ? 123.007 169.160 116.154 1.00 34.62 ? 70  ILE E CG1 1 
ATOM   7104 C CG2 . ILE E 5 70  ? 122.407 166.735 116.571 1.00 34.86 ? 70  ILE E CG2 1 
ATOM   7105 C CD1 . ILE E 5 70  ? 124.296 168.980 115.394 1.00 34.42 ? 70  ILE E CD1 1 
ATOM   7106 N N   . SER E 5 71  ? 119.969 166.801 118.587 1.00 26.68 ? 71  SER E N   1 
ATOM   7107 C CA  . SER E 5 71  ? 119.482 165.560 119.167 1.00 39.12 ? 71  SER E CA  1 
ATOM   7108 C C   . SER E 5 71  ? 118.881 164.730 118.043 1.00 37.23 ? 71  SER E C   1 
ATOM   7109 O O   . SER E 5 71  ? 118.559 165.251 116.973 1.00 36.05 ? 71  SER E O   1 
ATOM   7110 C CB  . SER E 5 71  ? 118.451 165.812 120.277 1.00 43.17 ? 71  SER E CB  1 
ATOM   7111 O OG  . SER E 5 71  ? 117.336 166.539 119.792 1.00 44.98 ? 71  SER E OG  1 
ATOM   7112 N N   . ARG E 5 72  ? 118.743 163.427 118.288 1.00 32.16 ? 72  ARG E N   1 
ATOM   7113 C CA  . ARG E 5 72  ? 118.279 162.500 117.265 1.00 32.49 ? 72  ARG E CA  1 
ATOM   7114 C C   . ARG E 5 72  ? 117.321 161.484 117.867 1.00 36.11 ? 72  ARG E C   1 
ATOM   7115 O O   . ARG E 5 72  ? 117.630 160.837 118.872 1.00 42.60 ? 72  ARG E O   1 
ATOM   7116 C CB  . ARG E 5 72  ? 119.465 161.798 116.592 1.00 34.63 ? 72  ARG E CB  1 
ATOM   7117 C CG  . ARG E 5 72  ? 120.255 160.873 117.501 1.00 37.93 ? 72  ARG E CG  1 
ATOM   7118 C CD  . ARG E 5 72  ? 121.607 160.480 116.910 1.00 34.84 ? 72  ARG E CD  1 
ATOM   7119 N NE  . ARG E 5 72  ? 121.553 160.097 115.500 1.00 25.62 ? 72  ARG E NE  1 
ATOM   7120 C CZ  . ARG E 5 72  ? 122.441 159.323 114.888 1.00 21.44 ? 72  ARG E CZ  1 
ATOM   7121 N NH1 . ARG E 5 72  ? 123.498 158.836 115.517 1.00 22.93 ? 72  ARG E NH1 1 
ATOM   7122 N NH2 . ARG E 5 72  ? 122.275 159.042 113.600 1.00 28.74 ? 72  ARG E NH2 1 
ATOM   7123 N N   . ASP E 5 73  ? 116.154 161.355 117.238 1.00 31.25 ? 73  ASP E N   1 
ATOM   7124 C CA  . ASP E 5 73  ? 115.107 160.430 117.655 1.00 38.35 ? 73  ASP E CA  1 
ATOM   7125 C C   . ASP E 5 73  ? 115.272 159.147 116.850 1.00 44.32 ? 73  ASP E C   1 
ATOM   7126 O O   . ASP E 5 73  ? 114.713 159.016 115.756 1.00 44.68 ? 73  ASP E O   1 
ATOM   7127 C CB  . ASP E 5 73  ? 113.726 161.054 117.450 1.00 37.14 ? 73  ASP E CB  1 
ATOM   7128 C CG  . ASP E 5 73  ? 112.649 160.401 118.297 1.00 44.24 ? 73  ASP E CG  1 
ATOM   7129 O OD1 . ASP E 5 73  ? 112.941 159.409 118.998 1.00 49.15 ? 73  ASP E OD1 1 
ATOM   7130 O OD2 . ASP E 5 73  ? 111.498 160.885 118.261 1.00 45.58 ? 73  ASP E OD2 1 
ATOM   7131 N N   . ASP E 5 74  ? 116.046 158.207 117.389 1.00 47.90 ? 74  ASP E N   1 
ATOM   7132 C CA  . ASP E 5 74  ? 116.371 156.970 116.688 1.00 45.33 ? 74  ASP E CA  1 
ATOM   7133 C C   . ASP E 5 74  ? 115.112 156.173 116.351 1.00 47.96 ? 74  ASP E C   1 
ATOM   7134 O O   . ASP E 5 74  ? 114.987 155.695 115.217 1.00 48.41 ? 74  ASP E O   1 
ATOM   7135 C CB  . ASP E 5 74  ? 117.335 156.113 117.521 1.00 45.84 ? 74  ASP E CB  1 
ATOM   7136 C CG  . ASP E 5 74  ? 118.805 156.323 117.156 1.00 43.97 ? 74  ASP E CG  1 
ATOM   7137 O OD1 . ASP E 5 74  ? 119.119 156.978 116.141 1.00 44.73 ? 74  ASP E OD1 1 
ATOM   7138 O OD2 . ASP E 5 74  ? 119.665 155.819 117.908 1.00 43.57 ? 74  ASP E OD2 1 
ATOM   7139 N N   . PRO E 5 75  ? 114.169 155.984 117.285 1.00 49.19 ? 75  PRO E N   1 
ATOM   7140 C CA  . PRO E 5 75  ? 112.896 155.354 116.894 1.00 46.62 ? 75  PRO E CA  1 
ATOM   7141 C C   . PRO E 5 75  ? 112.156 156.109 115.805 1.00 45.78 ? 75  PRO E C   1 
ATOM   7142 O O   . PRO E 5 75  ? 111.539 155.478 114.938 1.00 45.95 ? 75  PRO E O   1 
ATOM   7143 C CB  . PRO E 5 75  ? 112.099 155.335 118.205 1.00 50.24 ? 75  PRO E CB  1 
ATOM   7144 C CG  . PRO E 5 75  ? 113.124 155.310 119.260 1.00 53.18 ? 75  PRO E CG  1 
ATOM   7145 C CD  . PRO E 5 75  ? 114.254 156.150 118.749 1.00 51.24 ? 75  PRO E CD  1 
ATOM   7146 N N   . LYS E 5 76  ? 112.199 157.440 115.819 1.00 37.06 ? 76  LYS E N   1 
ATOM   7147 C CA  . LYS E 5 76  ? 111.537 158.232 114.792 1.00 40.71 ? 76  LYS E CA  1 
ATOM   7148 C C   . LYS E 5 76  ? 112.336 158.319 113.498 1.00 44.67 ? 76  LYS E C   1 
ATOM   7149 O O   . LYS E 5 76  ? 111.783 158.754 112.482 1.00 43.60 ? 76  LYS E O   1 
ATOM   7150 C CB  . LYS E 5 76  ? 111.265 159.644 115.316 1.00 37.58 ? 76  LYS E CB  1 
ATOM   7151 N N   . ASN E 5 77  ? 113.607 157.905 113.504 1.00 42.58 ? 77  ASN E N   1 
ATOM   7152 C CA  . ASN E 5 77  ? 114.483 157.997 112.334 1.00 37.71 ? 77  ASN E CA  1 
ATOM   7153 C C   . ASN E 5 77  ? 114.567 159.450 111.857 1.00 36.11 ? 77  ASN E C   1 
ATOM   7154 O O   . ASN E 5 77  ? 114.110 159.809 110.770 1.00 34.03 ? 77  ASN E O   1 
ATOM   7155 C CB  . ASN E 5 77  ? 114.011 157.054 111.211 1.00 31.93 ? 77  ASN E CB  1 
ATOM   7156 C CG  . ASN E 5 77  ? 114.807 155.754 111.144 1.00 35.20 ? 77  ASN E CG  1 
ATOM   7157 O OD1 . ASN E 5 77  ? 115.590 155.430 112.035 1.00 33.92 ? 77  ASN E OD1 1 
ATOM   7158 N ND2 . ASN E 5 77  ? 114.601 155.002 110.068 1.00 37.93 ? 77  ASN E ND2 1 
ATOM   7159 N N   . THR E 5 78  ? 115.129 160.306 112.708 1.00 27.85 ? 78  THR E N   1 
ATOM   7160 C CA  . THR E 5 78  ? 115.202 161.731 112.426 1.00 26.19 ? 78  THR E CA  1 
ATOM   7161 C C   . THR E 5 78  ? 116.202 162.369 113.381 1.00 31.64 ? 78  THR E C   1 
ATOM   7162 O O   . THR E 5 78  ? 116.339 161.954 114.534 1.00 37.67 ? 78  THR E O   1 
ATOM   7163 C CB  . THR E 5 78  ? 113.812 162.384 112.557 1.00 28.43 ? 78  THR E CB  1 
ATOM   7164 O OG1 . THR E 5 78  ? 112.967 161.921 111.497 1.00 30.75 ? 78  THR E OG1 1 
ATOM   7165 C CG2 . THR E 5 78  ? 113.887 163.902 112.468 1.00 27.12 ? 78  THR E CG2 1 
ATOM   7166 N N   . LEU E 5 79  ? 116.914 163.380 112.878 1.00 26.67 ? 79  LEU E N   1 
ATOM   7167 C CA  . LEU E 5 79  ? 117.783 164.211 113.701 1.00 34.91 ? 79  LEU E CA  1 
ATOM   7168 C C   . LEU E 5 79  ? 117.502 165.675 113.411 1.00 37.29 ? 79  LEU E C   1 
ATOM   7169 O O   . LEU E 5 79  ? 117.198 166.054 112.277 1.00 38.75 ? 79  LEU E O   1 
ATOM   7170 C CB  . LEU E 5 79  ? 119.274 163.893 113.491 1.00 28.37 ? 79  LEU E CB  1 
ATOM   7171 C CG  . LEU E 5 79  ? 120.088 164.544 112.369 1.00 30.69 ? 79  LEU E CG  1 
ATOM   7172 C CD1 . LEU E 5 79  ? 121.560 164.378 112.641 1.00 24.54 ? 79  LEU E CD1 1 
ATOM   7173 C CD2 . LEU E 5 79  ? 119.718 163.906 111.057 1.00 38.58 ? 79  LEU E CD2 1 
ATOM   7174 N N   . PHE E 5 80  ? 117.625 166.491 114.457 1.00 31.30 ? 80  PHE E N   1 
ATOM   7175 C CA  . PHE E 5 80  ? 117.235 167.891 114.425 1.00 29.46 ? 80  PHE E CA  1 
ATOM   7176 C C   . PHE E 5 80  ? 118.449 168.788 114.593 1.00 27.33 ? 80  PHE E C   1 
ATOM   7177 O O   . PHE E 5 80  ? 119.559 168.313 114.845 1.00 30.09 ? 80  PHE E O   1 
ATOM   7178 C CB  . PHE E 5 80  ? 116.238 168.213 115.531 1.00 38.10 ? 80  PHE E CB  1 
ATOM   7179 C CG  . PHE E 5 80  ? 115.415 167.044 115.973 1.00 33.35 ? 80  PHE E CG  1 
ATOM   7180 C CD1 . PHE E 5 80  ? 114.325 166.625 115.235 1.00 29.12 ? 80  PHE E CD1 1 
ATOM   7181 C CD2 . PHE E 5 80  ? 115.715 166.387 117.150 1.00 29.20 ? 80  PHE E CD2 1 
ATOM   7182 C CE1 . PHE E 5 80  ? 113.564 165.559 115.654 1.00 32.23 ? 80  PHE E CE1 1 
ATOM   7183 C CE2 . PHE E 5 80  ? 114.961 165.317 117.571 1.00 34.72 ? 80  PHE E CE2 1 
ATOM   7184 C CZ  . PHE E 5 80  ? 113.883 164.902 116.822 1.00 40.06 ? 80  PHE E CZ  1 
ATOM   7185 N N   . LEU E 5 81  ? 118.221 170.091 114.446 1.00 30.47 ? 81  LEU E N   1 
ATOM   7186 C CA  . LEU E 5 81  ? 119.209 171.122 114.741 1.00 32.27 ? 81  LEU E CA  1 
ATOM   7187 C C   . LEU E 5 81  ? 118.478 172.332 115.304 1.00 42.25 ? 81  LEU E C   1 
ATOM   7188 O O   . LEU E 5 81  ? 117.728 172.998 114.582 1.00 46.87 ? 81  LEU E O   1 
ATOM   7189 C CB  . LEU E 5 81  ? 120.003 171.501 113.489 1.00 32.95 ? 81  LEU E CB  1 
ATOM   7190 C CG  . LEU E 5 81  ? 121.140 172.513 113.653 1.00 23.64 ? 81  LEU E CG  1 
ATOM   7191 C CD1 . LEU E 5 81  ? 122.296 171.898 114.413 1.00 24.46 ? 81  LEU E CD1 1 
ATOM   7192 C CD2 . LEU E 5 81  ? 121.609 173.015 112.305 1.00 27.66 ? 81  LEU E CD2 1 
ATOM   7193 N N   . GLN E 5 82  ? 118.688 172.606 116.589 1.00 42.41 ? 82  GLN E N   1 
ATOM   7194 C CA  . GLN E 5 82  ? 118.083 173.741 117.275 1.00 31.99 ? 82  GLN E CA  1 
ATOM   7195 C C   . GLN E 5 82  ? 119.027 174.929 117.201 1.00 26.71 ? 82  GLN E C   1 
ATOM   7196 O O   . GLN E 5 82  ? 120.200 174.813 117.565 1.00 29.59 ? 82  GLN E O   1 
ATOM   7197 C CB  . GLN E 5 82  ? 117.788 173.406 118.738 1.00 40.50 ? 82  GLN E CB  1 
ATOM   7198 C CG  . GLN E 5 82  ? 116.320 173.412 119.098 1.00 44.04 ? 82  GLN E CG  1 
ATOM   7199 C CD  . GLN E 5 82  ? 115.720 174.807 119.124 1.00 45.68 ? 82  GLN E CD  1 
ATOM   7200 O OE1 . GLN E 5 82  ? 116.416 175.790 119.366 1.00 47.41 ? 82  GLN E OE1 1 
ATOM   7201 N NE2 . GLN E 5 82  ? 114.417 174.895 118.892 1.00 37.55 ? 82  GLN E NE2 1 
ATOM   7202 N N   . MET E 5 83  ? 118.511 176.064 116.737 1.00 30.46 ? 83  MET E N   1 
ATOM   7203 C CA  . MET E 5 83  ? 119.275 177.298 116.619 1.00 39.51 ? 83  MET E CA  1 
ATOM   7204 C C   . MET E 5 83  ? 118.630 178.363 117.491 1.00 39.42 ? 83  MET E C   1 
ATOM   7205 O O   . MET E 5 83  ? 117.407 178.533 117.463 1.00 39.67 ? 83  MET E O   1 
ATOM   7206 C CB  . MET E 5 83  ? 119.320 177.792 115.174 1.00 39.99 ? 83  MET E CB  1 
ATOM   7207 C CG  . MET E 5 83  ? 120.005 176.853 114.214 1.00 34.98 ? 83  MET E CG  1 
ATOM   7208 S SD  . MET E 5 83  ? 119.847 177.453 112.531 1.00 37.72 ? 83  MET E SD  1 
ATOM   7209 C CE  . MET E 5 83  ? 119.037 176.068 111.771 1.00 32.07 ? 83  MET E CE  1 
ATOM   7210 N N   . THR E 5 84  ? 119.454 179.073 118.257 1.00 35.86 ? 84  THR E N   1 
ATOM   7211 C CA  . THR E 5 84  ? 119.016 180.227 119.026 1.00 42.14 ? 84  THR E CA  1 
ATOM   7212 C C   . THR E 5 84  ? 120.018 181.351 118.823 1.00 39.79 ? 84  THR E C   1 
ATOM   7213 O O   . THR E 5 84  ? 121.195 181.108 118.546 1.00 39.34 ? 84  THR E O   1 
ATOM   7214 C CB  . THR E 5 84  ? 118.868 179.911 120.524 1.00 46.93 ? 84  THR E CB  1 
ATOM   7215 O OG1 . THR E 5 84  ? 118.755 181.132 121.266 1.00 52.08 ? 84  THR E OG1 1 
ATOM   7216 C CG2 . THR E 5 84  ? 120.054 179.110 121.040 1.00 38.73 ? 84  THR E CG2 1 
ATOM   7217 N N   . SER E 5 85  ? 119.540 182.586 118.971 1.00 43.39 ? 85  SER E N   1 
ATOM   7218 C CA  . SER E 5 85  ? 120.348 183.782 118.745 1.00 47.28 ? 85  SER E CA  1 
ATOM   7219 C C   . SER E 5 85  ? 120.957 183.766 117.340 1.00 43.34 ? 85  SER E C   1 
ATOM   7220 O O   . SER E 5 85  ? 122.174 183.813 117.155 1.00 42.39 ? 85  SER E O   1 
ATOM   7221 C CB  . SER E 5 85  ? 121.435 183.925 119.818 1.00 51.01 ? 85  SER E CB  1 
ATOM   7222 O OG  . SER E 5 85  ? 122.537 184.668 119.327 1.00 50.15 ? 85  SER E OG  1 
ATOM   7223 N N   . LEU E 5 86  ? 120.077 183.683 116.348 1.00 44.36 ? 86  LEU E N   1 
ATOM   7224 C CA  . LEU E 5 86  ? 120.493 183.781 114.959 1.00 45.66 ? 86  LEU E CA  1 
ATOM   7225 C C   . LEU E 5 86  ? 120.989 185.189 114.654 1.00 47.90 ? 86  LEU E C   1 
ATOM   7226 O O   . LEU E 5 86  ? 120.474 186.182 115.174 1.00 52.06 ? 86  LEU E O   1 
ATOM   7227 C CB  . LEU E 5 86  ? 119.338 183.427 114.023 1.00 41.08 ? 86  LEU E CB  1 
ATOM   7228 C CG  . LEU E 5 86  ? 118.891 181.967 114.006 1.00 43.01 ? 86  LEU E CG  1 
ATOM   7229 C CD1 . LEU E 5 86  ? 117.611 181.823 113.206 1.00 41.38 ? 86  LEU E CD1 1 
ATOM   7230 C CD2 . LEU E 5 86  ? 119.977 181.079 113.432 1.00 37.29 ? 86  LEU E CD2 1 
ATOM   7231 N N   . ARG E 5 87  ? 122.001 185.263 113.797 1.00 37.53 ? 87  ARG E N   1 
ATOM   7232 C CA  . ARG E 5 87  ? 122.600 186.522 113.374 1.00 43.10 ? 87  ARG E CA  1 
ATOM   7233 C C   . ARG E 5 87  ? 122.428 186.673 111.865 1.00 42.49 ? 87  ARG E C   1 
ATOM   7234 O O   . ARG E 5 87  ? 122.025 185.741 111.165 1.00 41.49 ? 87  ARG E O   1 
ATOM   7235 C CB  . ARG E 5 87  ? 124.073 186.603 113.789 1.00 37.89 ? 87  ARG E CB  1 
ATOM   7236 C CG  . ARG E 5 87  ? 124.932 185.395 113.442 1.00 37.43 ? 87  ARG E CG  1 
ATOM   7237 C CD  . ARG E 5 87  ? 126.258 185.450 114.180 1.00 42.16 ? 87  ARG E CD  1 
ATOM   7238 N NE  . ARG E 5 87  ? 126.102 185.194 115.608 1.00 44.76 ? 87  ARG E NE  1 
ATOM   7239 C CZ  . ARG E 5 87  ? 127.081 184.837 116.431 1.00 47.10 ? 87  ARG E CZ  1 
ATOM   7240 N NH1 . ARG E 5 87  ? 128.327 184.683 116.008 1.00 46.02 ? 87  ARG E NH1 1 
ATOM   7241 N NH2 . ARG E 5 87  ? 126.804 184.631 117.715 1.00 44.65 ? 87  ARG E NH2 1 
ATOM   7242 N N   . SER E 5 88  ? 122.736 187.868 111.367 1.00 44.64 ? 88  SER E N   1 
ATOM   7243 C CA  . SER E 5 88  ? 122.511 188.210 109.971 1.00 39.88 ? 88  SER E CA  1 
ATOM   7244 C C   . SER E 5 88  ? 123.397 187.432 109.005 1.00 33.60 ? 88  SER E C   1 
ATOM   7245 O O   . SER E 5 88  ? 123.093 187.404 107.807 1.00 30.32 ? 88  SER E O   1 
ATOM   7246 C CB  . SER E 5 88  ? 122.733 189.711 109.759 1.00 43.11 ? 88  SER E CB  1 
ATOM   7247 O OG  . SER E 5 88  ? 121.765 190.472 110.461 1.00 41.27 ? 88  SER E OG  1 
ATOM   7248 N N   . GLU E 5 89  ? 124.466 186.798 109.488 1.00 31.89 ? 89  GLU E N   1 
ATOM   7249 C CA  . GLU E 5 89  ? 125.450 186.141 108.637 1.00 37.35 ? 89  GLU E CA  1 
ATOM   7250 C C   . GLU E 5 89  ? 125.309 184.623 108.610 1.00 33.06 ? 89  GLU E C   1 
ATOM   7251 O O   . GLU E 5 89  ? 126.179 183.948 108.052 1.00 29.68 ? 89  GLU E O   1 
ATOM   7252 C CB  . GLU E 5 89  ? 126.861 186.515 109.093 1.00 34.91 ? 89  GLU E CB  1 
ATOM   7253 N N   . ASP E 5 90  ? 124.245 184.070 109.193 1.00 32.12 ? 90  ASP E N   1 
ATOM   7254 C CA  . ASP E 5 90  ? 124.013 182.631 109.205 1.00 29.07 ? 90  ASP E CA  1 
ATOM   7255 C C   . ASP E 5 90  ? 123.115 182.171 108.062 1.00 36.53 ? 90  ASP E C   1 
ATOM   7256 O O   . ASP E 5 90  ? 122.771 180.987 108.002 1.00 37.97 ? 90  ASP E O   1 
ATOM   7257 C CB  . ASP E 5 90  ? 123.402 182.207 110.545 1.00 27.67 ? 90  ASP E CB  1 
ATOM   7258 C CG  . ASP E 5 90  ? 124.444 181.982 111.632 1.00 30.84 ? 90  ASP E CG  1 
ATOM   7259 O OD1 . ASP E 5 90  ? 125.658 182.000 111.340 1.00 32.02 ? 90  ASP E OD1 1 
ATOM   7260 O OD2 . ASP E 5 90  ? 124.042 181.776 112.795 1.00 33.03 ? 90  ASP E OD2 1 
ATOM   7261 N N   . THR E 5 91  ? 122.722 183.071 107.161 1.00 34.55 ? 91  THR E N   1 
ATOM   7262 C CA  . THR E 5 91  ? 121.955 182.667 105.992 1.00 27.07 ? 91  THR E CA  1 
ATOM   7263 C C   . THR E 5 91  ? 122.775 181.694 105.154 1.00 27.34 ? 91  THR E C   1 
ATOM   7264 O O   . THR E 5 91  ? 123.929 181.970 104.815 1.00 39.39 ? 91  THR E O   1 
ATOM   7265 C CB  . THR E 5 91  ? 121.548 183.887 105.160 1.00 29.17 ? 91  THR E CB  1 
ATOM   7266 O OG1 . THR E 5 91  ? 120.748 183.464 104.050 1.00 32.34 ? 91  THR E OG1 1 
ATOM   7267 C CG2 . THR E 5 91  ? 122.762 184.659 104.629 1.00 33.38 ? 91  THR E CG2 1 
ATOM   7268 N N   . ALA E 5 92  ? 122.191 180.547 104.842 1.00 19.85 ? 92  ALA E N   1 
ATOM   7269 C CA  . ALA E 5 92  ? 122.910 179.481 104.152 1.00 27.33 ? 92  ALA E CA  1 
ATOM   7270 C C   . ALA E 5 92  ? 121.898 178.418 103.738 1.00 22.53 ? 92  ALA E C   1 
ATOM   7271 O O   . ALA E 5 92  ? 120.684 178.599 103.886 1.00 22.55 ? 92  ALA E O   1 
ATOM   7272 C CB  . ALA E 5 92  ? 124.014 178.902 105.040 1.00 25.20 ? 92  ALA E CB  1 
ATOM   7273 N N   . MET E 5 93  ? 122.410 177.312 103.204 1.00 18.55 ? 93  MET E N   1 
ATOM   7274 C CA  . MET E 5 93  ? 121.641 176.111 102.920 1.00 20.96 ? 93  MET E CA  1 
ATOM   7275 C C   . MET E 5 93  ? 122.288 174.963 103.676 1.00 25.95 ? 93  MET E C   1 
ATOM   7276 O O   . MET E 5 93  ? 123.456 174.644 103.445 1.00 25.49 ? 93  MET E O   1 
ATOM   7277 C CB  . MET E 5 93  ? 121.612 175.825 101.409 1.00 18.94 ? 93  MET E CB  1 
ATOM   7278 C CG  . MET E 5 93  ? 121.518 174.335 101.015 1.00 28.36 ? 93  MET E CG  1 
ATOM   7279 S SD  . MET E 5 93  ? 120.998 173.974 99.320  1.00 49.50 ? 93  MET E SD  1 
ATOM   7280 C CE  . MET E 5 93  ? 119.487 174.908 99.170  1.00 31.59 ? 93  MET E CE  1 
ATOM   7281 N N   . TYR E 5 94  ? 121.523 174.338 104.566 1.00 22.56 ? 94  TYR E N   1 
ATOM   7282 C CA  . TYR E 5 94  ? 122.038 173.325 105.475 1.00 14.15 ? 94  TYR E CA  1 
ATOM   7283 C C   . TYR E 5 94  ? 121.814 171.936 104.898 1.00 11.49 ? 94  TYR E C   1 
ATOM   7284 O O   . TYR E 5 94  ? 120.691 171.584 104.528 1.00 23.48 ? 94  TYR E O   1 
ATOM   7285 C CB  . TYR E 5 94  ? 121.371 173.438 106.847 1.00 15.09 ? 94  TYR E CB  1 
ATOM   7286 C CG  . TYR E 5 94  ? 121.851 174.625 107.647 1.00 18.13 ? 94  TYR E CG  1 
ATOM   7287 C CD1 . TYR E 5 94  ? 121.401 175.907 107.365 1.00 21.20 ? 94  TYR E CD1 1 
ATOM   7288 C CD2 . TYR E 5 94  ? 122.766 174.465 108.675 1.00 17.30 ? 94  TYR E CD2 1 
ATOM   7289 C CE1 . TYR E 5 94  ? 121.846 176.993 108.089 1.00 21.34 ? 94  TYR E CE1 1 
ATOM   7290 C CE2 . TYR E 5 94  ? 123.215 175.543 109.403 1.00 22.45 ? 94  TYR E CE2 1 
ATOM   7291 C CZ  . TYR E 5 94  ? 122.753 176.805 109.106 1.00 22.21 ? 94  TYR E CZ  1 
ATOM   7292 O OH  . TYR E 5 94  ? 123.200 177.883 109.831 1.00 24.02 ? 94  TYR E OH  1 
ATOM   7293 N N   . TYR E 5 95  ? 122.888 171.152 104.836 1.00 13.19 ? 95  TYR E N   1 
ATOM   7294 C CA  . TYR E 5 95  ? 122.872 169.817 104.260 1.00 13.08 ? 95  TYR E CA  1 
ATOM   7295 C C   . TYR E 5 95  ? 122.927 168.768 105.360 1.00 9.98  ? 95  TYR E C   1 
ATOM   7296 O O   . TYR E 5 95  ? 123.750 168.834 106.275 1.00 32.15 ? 95  TYR E O   1 
ATOM   7297 C CB  . TYR E 5 95  ? 124.049 169.602 103.300 1.00 9.94  ? 95  TYR E CB  1 
ATOM   7298 C CG  . TYR E 5 95  ? 123.920 170.349 101.998 1.00 4.91  ? 95  TYR E CG  1 
ATOM   7299 C CD1 . TYR E 5 95  ? 123.047 169.919 101.015 1.00 16.91 ? 95  TYR E CD1 1 
ATOM   7300 C CD2 . TYR E 5 95  ? 124.680 171.478 101.747 1.00 18.84 ? 95  TYR E CD2 1 
ATOM   7301 C CE1 . TYR E 5 95  ? 122.925 170.598 99.826  1.00 20.47 ? 95  TYR E CE1 1 
ATOM   7302 C CE2 . TYR E 5 95  ? 124.567 172.161 100.560 1.00 14.32 ? 95  TYR E CE2 1 
ATOM   7303 C CZ  . TYR E 5 95  ? 123.688 171.718 99.603  1.00 20.52 ? 95  TYR E CZ  1 
ATOM   7304 O OH  . TYR E 5 95  ? 123.573 172.399 98.415  1.00 32.52 ? 95  TYR E OH  1 
ATOM   7305 N N   . CYS E 5 96  ? 122.035 167.792 105.253 1.00 14.95 ? 96  CYS E N   1 
ATOM   7306 C CA  . CYS E 5 96  ? 122.020 166.620 106.117 1.00 13.12 ? 96  CYS E CA  1 
ATOM   7307 C C   . CYS E 5 96  ? 122.910 165.562 105.486 1.00 22.90 ? 96  CYS E C   1 
ATOM   7308 O O   . CYS E 5 96  ? 122.644 165.118 104.364 1.00 55.35 ? 96  CYS E O   1 
ATOM   7309 C CB  . CYS E 5 96  ? 120.595 166.099 106.289 1.00 26.65 ? 96  CYS E CB  1 
ATOM   7310 S SG  . CYS E 5 96  ? 120.379 164.891 107.585 1.00 36.69 ? 96  CYS E SG  1 
ATOM   7311 N N   . VAL E 5 97  ? 123.953 165.156 106.204 1.00 0.00  ? 97  VAL E N   1 
ATOM   7312 C CA  . VAL E 5 97  ? 124.992 164.289 105.667 1.00 7.59  ? 97  VAL E CA  1 
ATOM   7313 C C   . VAL E 5 97  ? 125.164 163.092 106.585 1.00 20.46 ? 97  VAL E C   1 
ATOM   7314 O O   . VAL E 5 97  ? 125.188 163.240 107.811 1.00 32.91 ? 97  VAL E O   1 
ATOM   7315 C CB  . VAL E 5 97  ? 126.323 165.045 105.522 1.00 0.60  ? 97  VAL E CB  1 
ATOM   7316 C CG1 . VAL E 5 97  ? 127.409 164.110 105.006 1.00 10.75 ? 97  VAL E CG1 1 
ATOM   7317 C CG2 . VAL E 5 97  ? 126.129 166.252 104.640 1.00 14.18 ? 97  VAL E CG2 1 
ATOM   7318 N N   . ARG E 5 98  ? 125.285 161.910 105.991 1.00 20.80 ? 98  ARG E N   1 
ATOM   7319 C CA  . ARG E 5 98  ? 125.538 160.678 106.720 1.00 17.71 ? 98  ARG E CA  1 
ATOM   7320 C C   . ARG E 5 98  ? 127.020 160.339 106.657 1.00 13.31 ? 98  ARG E C   1 
ATOM   7321 O O   . ARG E 5 98  ? 127.771 160.878 105.843 1.00 26.35 ? 98  ARG E O   1 
ATOM   7322 C CB  . ARG E 5 98  ? 124.687 159.527 106.164 1.00 20.79 ? 98  ARG E CB  1 
ATOM   7323 C CG  . ARG E 5 98  ? 125.399 158.555 105.228 1.00 24.70 ? 98  ARG E CG  1 
ATOM   7324 C CD  . ARG E 5 98  ? 124.415 157.612 104.567 1.00 31.44 ? 98  ARG E CD  1 
ATOM   7325 N NE  . ARG E 5 98  ? 125.097 156.550 103.839 1.00 25.56 ? 98  ARG E NE  1 
ATOM   7326 C CZ  . ARG E 5 98  ? 124.493 155.605 103.130 1.00 23.87 ? 98  ARG E CZ  1 
ATOM   7327 N NH1 . ARG E 5 98  ? 123.176 155.555 103.015 1.00 27.42 ? 98  ARG E NH1 1 
ATOM   7328 N NH2 . ARG E 5 98  ? 125.231 154.683 102.520 1.00 30.39 ? 98  ARG E NH2 1 
ATOM   7329 N N   . SER E 5 99  ? 127.433 159.439 107.544 1.00 12.99 ? 99  SER E N   1 
ATOM   7330 C CA  . SER E 5 99  ? 128.811 158.977 107.595 1.00 9.29  ? 99  SER E CA  1 
ATOM   7331 C C   . SER E 5 99  ? 128.886 157.785 108.535 1.00 21.70 ? 99  SER E C   1 
ATOM   7332 O O   . SER E 5 99  ? 128.293 157.809 109.614 1.00 40.35 ? 99  SER E O   1 
ATOM   7333 C CB  . SER E 5 99  ? 129.756 160.085 108.067 1.00 15.23 ? 99  SER E CB  1 
ATOM   7334 O OG  . SER E 5 99  ? 129.617 160.299 109.457 1.00 24.05 ? 99  SER E OG  1 
ATOM   7335 N N   . ILE E 5 100 ? 129.621 156.756 108.123 1.00 10.65 ? 100 ILE E N   1 
ATOM   7336 C CA  . ILE E 5 100 ? 129.836 155.559 108.926 1.00 15.24 ? 100 ILE E CA  1 
ATOM   7337 C C   . ILE E 5 100 ? 131.330 155.286 108.973 1.00 14.42 ? 100 ILE E C   1 
ATOM   7338 O O   . ILE E 5 100 ? 132.005 155.323 107.939 1.00 31.16 ? 100 ILE E O   1 
ATOM   7339 C CB  . ILE E 5 100 ? 129.070 154.342 108.364 1.00 15.15 ? 100 ILE E CB  1 
ATOM   7340 C CG1 . ILE E 5 100 ? 129.262 153.132 109.275 1.00 27.41 ? 100 ILE E CG1 1 
ATOM   7341 C CG2 . ILE E 5 100 ? 129.513 154.010 106.936 1.00 16.45 ? 100 ILE E CG2 1 
ATOM   7342 C CD1 . ILE E 5 100 ? 128.207 152.071 109.104 1.00 27.70 ? 100 ILE E CD1 1 
ATOM   7343 N N   . TYR E 5 101 ? 131.847 155.014 110.171 1.00 13.85 ? 101 TYR E N   1 
ATOM   7344 C CA  . TYR E 5 101 ? 133.284 154.909 110.415 1.00 16.87 ? 101 TYR E CA  1 
ATOM   7345 C C   . TYR E 5 101 ? 133.626 153.506 110.895 1.00 18.72 ? 101 TYR E C   1 
ATOM   7346 O O   . TYR E 5 101 ? 133.336 153.145 112.040 1.00 25.34 ? 101 TYR E O   1 
ATOM   7347 C CB  . TYR E 5 101 ? 133.740 155.951 111.433 1.00 25.14 ? 101 TYR E CB  1 
ATOM   7348 C CG  . TYR E 5 101 ? 133.559 157.375 110.969 1.00 18.98 ? 101 TYR E CG  1 
ATOM   7349 C CD1 . TYR E 5 101 ? 134.425 157.939 110.049 1.00 19.63 ? 101 TYR E CD1 1 
ATOM   7350 C CD2 . TYR E 5 101 ? 132.521 158.155 111.451 1.00 16.41 ? 101 TYR E CD2 1 
ATOM   7351 C CE1 . TYR E 5 101 ? 134.262 159.236 109.625 1.00 20.12 ? 101 TYR E CE1 1 
ATOM   7352 C CE2 . TYR E 5 101 ? 132.355 159.451 111.036 1.00 10.17 ? 101 TYR E CE2 1 
ATOM   7353 C CZ  . TYR E 5 101 ? 133.225 159.987 110.124 1.00 15.26 ? 101 TYR E CZ  1 
ATOM   7354 O OH  . TYR E 5 101 ? 133.056 161.280 109.704 1.00 18.91 ? 101 TYR E OH  1 
ATOM   7355 N N   . TYR E 5 102 ? 134.237 152.721 110.013 1.00 19.85 ? 102 TYR E N   1 
ATOM   7356 C CA  . TYR E 5 102 ? 134.925 151.494 110.384 1.00 23.59 ? 102 TYR E CA  1 
ATOM   7357 C C   . TYR E 5 102 ? 136.036 151.286 109.365 1.00 29.13 ? 102 TYR E C   1 
ATOM   7358 O O   . TYR E 5 102 ? 136.218 152.094 108.450 1.00 32.13 ? 102 TYR E O   1 
ATOM   7359 C CB  . TYR E 5 102 ? 133.966 150.301 110.460 1.00 13.75 ? 102 TYR E CB  1 
ATOM   7360 C CG  . TYR E 5 102 ? 133.157 150.051 109.210 1.00 4.98  ? 102 TYR E CG  1 
ATOM   7361 C CD1 . TYR E 5 102 ? 133.680 149.329 108.152 1.00 11.02 ? 102 TYR E CD1 1 
ATOM   7362 C CD2 . TYR E 5 102 ? 131.862 150.521 109.098 1.00 9.55  ? 102 TYR E CD2 1 
ATOM   7363 C CE1 . TYR E 5 102 ? 132.942 149.098 107.014 1.00 17.10 ? 102 TYR E CE1 1 
ATOM   7364 C CE2 . TYR E 5 102 ? 131.116 150.296 107.966 1.00 8.26  ? 102 TYR E CE2 1 
ATOM   7365 C CZ  . TYR E 5 102 ? 131.660 149.584 106.927 1.00 13.12 ? 102 TYR E CZ  1 
ATOM   7366 O OH  . TYR E 5 102 ? 130.918 149.354 105.794 1.00 28.45 ? 102 TYR E OH  1 
ATOM   7367 N N   . TYR E 5 103 ? 136.791 150.204 109.526 1.00 15.18 ? 103 TYR E N   1 
ATOM   7368 C CA  . TYR E 5 103 ? 137.903 149.943 108.621 1.00 15.01 ? 103 TYR E CA  1 
ATOM   7369 C C   . TYR E 5 103 ? 137.377 149.701 107.211 1.00 10.15 ? 103 TYR E C   1 
ATOM   7370 O O   . TYR E 5 103 ? 136.577 148.788 106.986 1.00 16.35 ? 103 TYR E O   1 
ATOM   7371 C CB  . TYR E 5 103 ? 138.716 148.746 109.098 1.00 18.66 ? 103 TYR E CB  1 
ATOM   7372 C CG  . TYR E 5 103 ? 139.865 148.421 108.177 1.00 17.94 ? 103 TYR E CG  1 
ATOM   7373 C CD1 . TYR E 5 103 ? 141.025 149.180 108.190 1.00 20.61 ? 103 TYR E CD1 1 
ATOM   7374 C CD2 . TYR E 5 103 ? 139.783 147.369 107.281 1.00 17.47 ? 103 TYR E CD2 1 
ATOM   7375 C CE1 . TYR E 5 103 ? 142.075 148.891 107.343 1.00 23.79 ? 103 TYR E CE1 1 
ATOM   7376 C CE2 . TYR E 5 103 ? 140.828 147.071 106.430 1.00 24.19 ? 103 TYR E CE2 1 
ATOM   7377 C CZ  . TYR E 5 103 ? 141.969 147.837 106.464 1.00 30.65 ? 103 TYR E CZ  1 
ATOM   7378 O OH  . TYR E 5 103 ? 143.013 147.544 105.619 1.00 25.67 ? 103 TYR E OH  1 
ATOM   7379 N N   . GLY E 5 104 ? 137.832 150.515 106.264 1.00 16.75 ? 104 GLY E N   1 
ATOM   7380 C CA  . GLY E 5 104 ? 137.389 150.414 104.891 1.00 20.24 ? 104 GLY E CA  1 
ATOM   7381 C C   . GLY E 5 104 ? 136.085 151.111 104.583 1.00 13.21 ? 104 GLY E C   1 
ATOM   7382 O O   . GLY E 5 104 ? 135.514 150.870 103.513 1.00 7.05  ? 104 GLY E O   1 
ATOM   7383 N N   . SER E 5 105 ? 135.594 151.963 105.476 1.00 10.64 ? 105 SER E N   1 
ATOM   7384 C CA  . SER E 5 105 ? 134.333 152.647 105.252 1.00 12.65 ? 105 SER E CA  1 
ATOM   7385 C C   . SER E 5 105 ? 134.523 153.827 104.303 1.00 14.16 ? 105 SER E C   1 
ATOM   7386 O O   . SER E 5 105 ? 135.642 154.228 103.976 1.00 29.55 ? 105 SER E O   1 
ATOM   7387 C CB  . SER E 5 105 ? 133.744 153.128 106.574 1.00 20.92 ? 105 SER E CB  1 
ATOM   7388 O OG  . SER E 5 105 ? 134.640 153.997 107.243 1.00 20.07 ? 105 SER E OG  1 
ATOM   7389 N N   . SER E 5 106 ? 133.396 154.382 103.859 1.00 9.67  ? 106 SER E N   1 
ATOM   7390 C CA  . SER E 5 106 ? 133.359 155.505 102.925 1.00 17.00 ? 106 SER E CA  1 
ATOM   7391 C C   . SER E 5 106 ? 132.417 156.561 103.487 1.00 13.66 ? 106 SER E C   1 
ATOM   7392 O O   . SER E 5 106 ? 131.263 156.665 103.053 1.00 19.33 ? 106 SER E O   1 
ATOM   7393 C CB  . SER E 5 106 ? 132.911 155.049 101.540 1.00 18.02 ? 106 SER E CB  1 
ATOM   7394 O OG  . SER E 5 106 ? 131.513 154.837 101.497 1.00 11.32 ? 106 SER E OG  1 
ATOM   7395 N N   . PRO E 5 107 ? 132.863 157.356 104.458 1.00 9.91  ? 107 PRO E N   1 
ATOM   7396 C CA  . PRO E 5 107 ? 131.972 158.359 105.052 1.00 19.73 ? 107 PRO E CA  1 
ATOM   7397 C C   . PRO E 5 107 ? 131.633 159.467 104.066 1.00 14.93 ? 107 PRO E C   1 
ATOM   7398 O O   . PRO E 5 107 ? 132.245 159.617 103.009 1.00 30.10 ? 107 PRO E O   1 
ATOM   7399 C CB  . PRO E 5 107 ? 132.773 158.888 106.243 1.00 20.88 ? 107 PRO E CB  1 
ATOM   7400 C CG  . PRO E 5 107 ? 134.170 158.587 105.925 1.00 9.09  ? 107 PRO E CG  1 
ATOM   7401 C CD  . PRO E 5 107 ? 134.159 157.312 105.154 1.00 13.59 ? 107 PRO E CD  1 
ATOM   7402 N N   . PHE E 5 108 ? 130.616 160.248 104.436 1.00 11.12 ? 108 PHE E N   1 
ATOM   7403 C CA  . PHE E 5 108 ? 130.110 161.350 103.613 1.00 5.96  ? 108 PHE E CA  1 
ATOM   7404 C C   . PHE E 5 108 ? 129.621 160.853 102.254 1.00 15.56 ? 108 PHE E C   1 
ATOM   7405 O O   . PHE E 5 108 ? 129.662 161.576 101.258 1.00 27.47 ? 108 PHE E O   1 
ATOM   7406 C CB  . PHE E 5 108 ? 131.165 162.446 103.438 1.00 9.48  ? 108 PHE E CB  1 
ATOM   7407 C CG  . PHE E 5 108 ? 131.497 163.178 104.704 1.00 15.23 ? 108 PHE E CG  1 
ATOM   7408 C CD1 . PHE E 5 108 ? 132.387 162.647 105.615 1.00 13.78 ? 108 PHE E CD1 1 
ATOM   7409 C CD2 . PHE E 5 108 ? 130.924 164.406 104.975 1.00 18.92 ? 108 PHE E CD2 1 
ATOM   7410 C CE1 . PHE E 5 108 ? 132.688 163.321 106.773 1.00 11.89 ? 108 PHE E CE1 1 
ATOM   7411 C CE2 . PHE E 5 108 ? 131.223 165.083 106.131 1.00 5.00  ? 108 PHE E CE2 1 
ATOM   7412 C CZ  . PHE E 5 108 ? 132.106 164.541 107.031 1.00 15.68 ? 108 PHE E CZ  1 
ATOM   7413 N N   . ASP E 5 109 ? 129.129 159.617 102.212 1.00 15.82 ? 109 ASP E N   1 
ATOM   7414 C CA  . ASP E 5 109 ? 128.735 159.000 100.952 1.00 22.21 ? 109 ASP E CA  1 
ATOM   7415 C C   . ASP E 5 109 ? 127.360 159.435 100.460 1.00 21.65 ? 109 ASP E C   1 
ATOM   7416 O O   . ASP E 5 109 ? 127.073 159.259 99.271  1.00 26.79 ? 109 ASP E O   1 
ATOM   7417 C CB  . ASP E 5 109 ? 128.766 157.469 101.064 1.00 26.95 ? 109 ASP E CB  1 
ATOM   7418 C CG  . ASP E 5 109 ? 127.916 156.940 102.202 1.00 25.83 ? 109 ASP E CG  1 
ATOM   7419 O OD1 . ASP E 5 109 ? 127.293 157.756 102.910 1.00 27.03 ? 109 ASP E OD1 1 
ATOM   7420 O OD2 . ASP E 5 109 ? 127.882 155.708 102.396 1.00 27.01 ? 109 ASP E OD2 1 
ATOM   7421 N N   . PHE E 5 110 ? 126.511 159.990 101.325 1.00 11.66 ? 110 PHE E N   1 
ATOM   7422 C CA  . PHE E 5 110 ? 125.208 160.497 100.913 1.00 22.60 ? 110 PHE E CA  1 
ATOM   7423 C C   . PHE E 5 110 ? 124.936 161.827 101.592 1.00 21.58 ? 110 PHE E C   1 
ATOM   7424 O O   . PHE E 5 110 ? 125.335 162.041 102.739 1.00 34.60 ? 110 PHE E O   1 
ATOM   7425 C CB  . PHE E 5 110 ? 124.079 159.515 101.242 1.00 27.68 ? 110 PHE E CB  1 
ATOM   7426 C CG  . PHE E 5 110 ? 122.836 159.739 100.430 1.00 25.80 ? 110 PHE E CG  1 
ATOM   7427 C CD1 . PHE E 5 110 ? 122.812 159.457 99.077  1.00 28.29 ? 110 PHE E CD1 1 
ATOM   7428 C CD2 . PHE E 5 110 ? 121.697 160.253 101.018 1.00 30.23 ? 110 PHE E CD2 1 
ATOM   7429 C CE1 . PHE E 5 110 ? 121.675 159.673 98.331  1.00 29.20 ? 110 PHE E CE1 1 
ATOM   7430 C CE2 . PHE E 5 110 ? 120.557 160.472 100.275 1.00 29.20 ? 110 PHE E CE2 1 
ATOM   7431 C CZ  . PHE E 5 110 ? 120.546 160.182 98.931  1.00 26.24 ? 110 PHE E CZ  1 
ATOM   7432 N N   . TRP E 5 111 ? 124.247 162.711 100.872 1.00 24.31 ? 111 TRP E N   1 
ATOM   7433 C CA  . TRP E 5 111 ? 123.951 164.066 101.313 1.00 17.36 ? 111 TRP E CA  1 
ATOM   7434 C C   . TRP E 5 111 ? 122.464 164.333 101.148 1.00 13.95 ? 111 TRP E C   1 
ATOM   7435 O O   . TRP E 5 111 ? 121.814 163.748 100.279 1.00 33.15 ? 111 TRP E O   1 
ATOM   7436 C CB  . TRP E 5 111 ? 124.749 165.099 100.511 1.00 22.12 ? 111 TRP E CB  1 
ATOM   7437 C CG  . TRP E 5 111 ? 126.209 165.152 100.845 1.00 25.88 ? 111 TRP E CG  1 
ATOM   7438 C CD1 . TRP E 5 111 ? 127.117 164.145 100.721 1.00 25.56 ? 111 TRP E CD1 1 
ATOM   7439 C CD2 . TRP E 5 111 ? 126.931 166.282 101.343 1.00 20.43 ? 111 TRP E CD2 1 
ATOM   7440 N NE1 . TRP E 5 111 ? 128.358 164.572 101.120 1.00 16.11 ? 111 TRP E NE1 1 
ATOM   7441 C CE2 . TRP E 5 111 ? 128.270 165.882 101.506 1.00 18.63 ? 111 TRP E CE2 1 
ATOM   7442 C CE3 . TRP E 5 111 ? 126.573 167.591 101.675 1.00 24.04 ? 111 TRP E CE3 1 
ATOM   7443 C CZ2 . TRP E 5 111 ? 129.251 166.743 101.983 1.00 28.43 ? 111 TRP E CZ2 1 
ATOM   7444 C CZ3 . TRP E 5 111 ? 127.550 168.443 102.145 1.00 35.11 ? 111 TRP E CZ3 1 
ATOM   7445 C CH2 . TRP E 5 111 ? 128.872 168.016 102.296 1.00 29.40 ? 111 TRP E CH2 1 
ATOM   7446 N N   . GLY E 5 112 ? 121.931 165.222 101.978 1.00 16.13 ? 112 GLY E N   1 
ATOM   7447 C CA  . GLY E 5 112 ? 120.530 165.570 101.912 1.00 14.27 ? 112 GLY E CA  1 
ATOM   7448 C C   . GLY E 5 112 ? 120.222 166.512 100.767 1.00 13.90 ? 112 GLY E C   1 
ATOM   7449 O O   . GLY E 5 112 ? 121.084 166.893 99.977  1.00 12.64 ? 112 GLY E O   1 
ATOM   7450 N N   . GLN E 5 113 ? 118.945 166.889 100.681 1.00 22.63 ? 113 GLN E N   1 
ATOM   7451 C CA  . GLN E 5 113 ? 118.510 167.772 99.602  1.00 27.29 ? 113 GLN E CA  1 
ATOM   7452 C C   . GLN E 5 113 ? 118.942 169.210 99.857  1.00 26.77 ? 113 GLN E C   1 
ATOM   7453 O O   . GLN E 5 113 ? 119.333 169.919 98.922  1.00 32.00 ? 113 GLN E O   1 
ATOM   7454 C CB  . GLN E 5 113 ? 116.988 167.711 99.407  1.00 20.82 ? 113 GLN E CB  1 
ATOM   7455 C CG  . GLN E 5 113 ? 116.304 166.345 99.580  1.00 18.52 ? 113 GLN E CG  1 
ATOM   7456 C CD  . GLN E 5 113 ? 116.521 165.427 98.393  1.00 28.17 ? 113 GLN E CD  1 
ATOM   7457 O OE1 . GLN E 5 113 ? 117.021 165.847 97.350  1.00 36.25 ? 113 GLN E OE1 1 
ATOM   7458 N NE2 . GLN E 5 113 ? 116.143 164.163 98.547  1.00 24.37 ? 113 GLN E NE2 1 
ATOM   7459 N N   . GLY E 5 114 ? 118.874 169.658 101.109 1.00 8.65  ? 114 GLY E N   1 
ATOM   7460 C CA  . GLY E 5 114 ? 119.206 171.026 101.460 1.00 19.11 ? 114 GLY E CA  1 
ATOM   7461 C C   . GLY E 5 114 ? 117.980 171.907 101.564 1.00 27.75 ? 114 GLY E C   1 
ATOM   7462 O O   . GLY E 5 114 ? 117.119 171.881 100.679 1.00 30.73 ? 114 GLY E O   1 
ATOM   7463 N N   . THR E 5 115 ? 117.886 172.686 102.643 1.00 29.11 ? 115 THR E N   1 
ATOM   7464 C CA  . THR E 5 115 ? 116.810 173.649 102.842 1.00 28.75 ? 115 THR E CA  1 
ATOM   7465 C C   . THR E 5 115 ? 117.405 175.023 103.090 1.00 27.10 ? 115 THR E C   1 
ATOM   7466 O O   . THR E 5 115 ? 118.261 175.189 103.963 1.00 30.55 ? 115 THR E O   1 
ATOM   7467 C CB  . THR E 5 115 ? 115.892 173.284 104.023 1.00 34.37 ? 115 THR E CB  1 
ATOM   7468 O OG1 . THR E 5 115 ? 116.624 173.378 105.251 1.00 26.84 ? 115 THR E OG1 1 
ATOM   7469 C CG2 . THR E 5 115 ? 115.273 171.894 103.869 1.00 35.55 ? 115 THR E CG2 1 
ATOM   7470 N N   . THR E 5 116 ? 116.937 176.006 102.329 1.00 30.28 ? 116 THR E N   1 
ATOM   7471 C CA  . THR E 5 116 ? 117.428 177.369 102.461 1.00 32.02 ? 116 THR E CA  1 
ATOM   7472 C C   . THR E 5 116 ? 116.920 177.969 103.762 1.00 31.60 ? 116 THR E C   1 
ATOM   7473 O O   . THR E 5 116 ? 115.747 177.816 104.115 1.00 39.07 ? 116 THR E O   1 
ATOM   7474 C CB  . THR E 5 116 ? 117.001 178.263 101.287 1.00 33.02 ? 116 THR E CB  1 
ATOM   7475 O OG1 . THR E 5 116 ? 115.723 178.847 101.565 1.00 34.97 ? 116 THR E OG1 1 
ATOM   7476 C CG2 . THR E 5 116 ? 116.968 177.521 99.959  1.00 32.15 ? 116 THR E CG2 1 
ATOM   7477 N N   . LEU E 5 117 ? 117.818 178.640 104.478 1.00 32.63 ? 117 LEU E N   1 
ATOM   7478 C CA  . LEU E 5 117 ? 117.471 179.449 105.637 1.00 35.24 ? 117 LEU E CA  1 
ATOM   7479 C C   . LEU E 5 117 ? 118.051 180.836 105.418 1.00 41.17 ? 117 LEU E C   1 
ATOM   7480 O O   . LEU E 5 117 ? 119.262 180.978 105.227 1.00 48.35 ? 117 LEU E O   1 
ATOM   7481 C CB  . LEU E 5 117 ? 118.002 178.832 106.940 1.00 28.64 ? 117 LEU E CB  1 
ATOM   7482 C CG  . LEU E 5 117 ? 117.960 179.707 108.199 1.00 28.90 ? 117 LEU E CG  1 
ATOM   7483 C CD1 . LEU E 5 117 ? 117.520 178.894 109.400 1.00 38.19 ? 117 LEU E CD1 1 
ATOM   7484 C CD2 . LEU E 5 117 ? 119.314 180.341 108.488 1.00 34.04 ? 117 LEU E CD2 1 
ATOM   7485 N N   . THR E 5 118 ? 117.185 181.846 105.425 1.00 36.91 ? 118 THR E N   1 
ATOM   7486 C CA  . THR E 5 118 ? 117.580 183.234 105.245 1.00 36.46 ? 118 THR E CA  1 
ATOM   7487 C C   . THR E 5 118 ? 117.089 184.052 106.430 1.00 35.77 ? 118 THR E C   1 
ATOM   7488 O O   . THR E 5 118 ? 116.116 183.686 107.095 1.00 41.37 ? 118 THR E O   1 
ATOM   7489 C CB  . THR E 5 118 ? 117.033 183.817 103.931 1.00 40.08 ? 118 THR E CB  1 
ATOM   7490 O OG1 . THR E 5 118 ? 117.550 185.140 103.742 1.00 46.40 ? 118 THR E OG1 1 
ATOM   7491 C CG2 . THR E 5 118 ? 115.512 183.868 103.936 1.00 42.14 ? 118 THR E CG2 1 
ATOM   7492 N N   . VAL E 5 119 ? 117.775 185.163 106.680 1.00 37.03 ? 119 VAL E N   1 
ATOM   7493 C CA  . VAL E 5 119 ? 117.540 185.983 107.865 1.00 38.69 ? 119 VAL E CA  1 
ATOM   7494 C C   . VAL E 5 119 ? 117.359 187.447 107.478 1.00 34.47 ? 119 VAL E C   1 
ATOM   7495 O O   . VAL E 5 119 ? 118.096 187.978 106.649 1.00 37.02 ? 119 VAL E O   1 
ATOM   7496 C CB  . VAL E 5 119 ? 118.690 185.821 108.885 1.00 32.16 ? 119 VAL E CB  1 
ATOM   7497 C CG1 . VAL E 5 119 ? 118.801 184.377 109.335 1.00 30.01 ? 119 VAL E CG1 1 
ATOM   7498 C CG2 . VAL E 5 119 ? 120.016 186.285 108.295 1.00 41.24 ? 119 VAL E CG2 1 
ATOM   7499 N N   . ASP E 5 137 ? 143.472 175.066 113.332 1.00 48.81 ? 125 ASP E N   1 
ATOM   7500 C CA  . ASP E 5 137 ? 142.597 174.673 112.234 1.00 47.70 ? 125 ASP E CA  1 
ATOM   7501 C C   . ASP E 5 137 ? 143.391 174.532 110.942 1.00 47.58 ? 125 ASP E C   1 
ATOM   7502 O O   . ASP E 5 137 ? 144.195 175.398 110.602 1.00 49.66 ? 125 ASP E O   1 
ATOM   7503 C CB  . ASP E 5 137 ? 141.473 175.693 112.052 1.00 49.77 ? 125 ASP E CB  1 
ATOM   7504 C CG  . ASP E 5 137 ? 140.575 175.793 113.267 1.00 54.06 ? 125 ASP E CG  1 
ATOM   7505 O OD1 . ASP E 5 137 ? 140.719 174.958 114.184 1.00 52.68 ? 125 ASP E OD1 1 
ATOM   7506 O OD2 . ASP E 5 137 ? 139.721 176.703 113.305 1.00 56.95 ? 125 ASP E OD2 1 
ATOM   7507 N N   . ILE E 5 138 ? 143.158 173.438 110.219 1.00 36.01 ? 126 ILE E N   1 
ATOM   7508 C CA  . ILE E 5 138 ? 143.868 173.205 108.969 1.00 36.16 ? 126 ILE E CA  1 
ATOM   7509 C C   . ILE E 5 138 ? 143.282 174.120 107.903 1.00 33.63 ? 126 ILE E C   1 
ATOM   7510 O O   . ILE E 5 138 ? 142.081 174.066 107.608 1.00 30.70 ? 126 ILE E O   1 
ATOM   7511 C CB  . ILE E 5 138 ? 143.768 171.725 108.565 1.00 32.56 ? 126 ILE E CB  1 
ATOM   7512 C CG1 . ILE E 5 138 ? 144.188 170.846 109.754 1.00 36.64 ? 126 ILE E CG1 1 
ATOM   7513 C CG2 . ILE E 5 138 ? 144.639 171.427 107.319 1.00 32.49 ? 126 ILE E CG2 1 
ATOM   7514 C CD1 . ILE E 5 138 ? 144.714 169.456 109.412 1.00 33.42 ? 126 ILE E CD1 1 
ATOM   7515 N N   . VAL E 5 139 ? 144.129 174.962 107.321 1.00 39.55 ? 127 VAL E N   1 
ATOM   7516 C CA  . VAL E 5 139 ? 143.729 175.883 106.263 1.00 41.45 ? 127 VAL E CA  1 
ATOM   7517 C C   . VAL E 5 139 ? 144.040 175.217 104.931 1.00 37.95 ? 127 VAL E C   1 
ATOM   7518 O O   . VAL E 5 139 ? 145.170 174.771 104.701 1.00 38.85 ? 127 VAL E O   1 
ATOM   7519 C CB  . VAL E 5 139 ? 144.447 177.236 106.390 1.00 47.11 ? 127 VAL E CB  1 
ATOM   7520 C CG1 . VAL E 5 139 ? 144.034 178.171 105.254 1.00 38.59 ? 127 VAL E CG1 1 
ATOM   7521 C CG2 . VAL E 5 139 ? 144.153 177.872 107.747 1.00 43.04 ? 127 VAL E CG2 1 
ATOM   7522 N N   . MET E 5 140 ? 143.037 175.144 104.062 1.00 39.60 ? 128 MET E N   1 
ATOM   7523 C CA  . MET E 5 140 ? 143.155 174.520 102.751 1.00 41.41 ? 128 MET E CA  1 
ATOM   7524 C C   . MET E 5 140 ? 142.721 175.499 101.674 1.00 39.65 ? 128 MET E C   1 
ATOM   7525 O O   . MET E 5 140 ? 141.681 176.152 101.803 1.00 44.67 ? 128 MET E O   1 
ATOM   7526 C CB  . MET E 5 140 ? 142.311 173.249 102.671 1.00 36.96 ? 128 MET E CB  1 
ATOM   7527 C CG  . MET E 5 140 ? 142.894 172.092 103.436 1.00 29.85 ? 128 MET E CG  1 
ATOM   7528 S SD  . MET E 5 140 ? 142.663 170.555 102.548 1.00 38.38 ? 128 MET E SD  1 
ATOM   7529 C CE  . MET E 5 140 ? 143.547 169.458 103.634 1.00 30.56 ? 128 MET E CE  1 
ATOM   7530 N N   . THR E 5 141 ? 143.521 175.588 100.616 1.00 39.33 ? 129 THR E N   1 
ATOM   7531 C CA  . THR E 5 141 ? 143.283 176.495 99.505  1.00 45.58 ? 129 THR E CA  1 
ATOM   7532 C C   . THR E 5 141 ? 143.309 175.718 98.198  1.00 41.29 ? 129 THR E C   1 
ATOM   7533 O O   . THR E 5 141 ? 144.168 174.854 97.996  1.00 43.07 ? 129 THR E O   1 
ATOM   7534 C CB  . THR E 5 141 ? 144.331 177.624 99.471  1.00 55.45 ? 129 THR E CB  1 
ATOM   7535 O OG1 . THR E 5 141 ? 144.092 178.471 98.340  1.00 58.31 ? 129 THR E OG1 1 
ATOM   7536 C CG2 . THR E 5 141 ? 145.762 177.071 99.400  1.00 49.04 ? 129 THR E CG2 1 
ATOM   7537 N N   . GLN E 5 142 ? 142.354 176.023 97.325  1.00 43.39 ? 130 GLN E N   1 
ATOM   7538 C CA  . GLN E 5 142 ? 142.340 175.539 95.951  1.00 48.77 ? 130 GLN E CA  1 
ATOM   7539 C C   . GLN E 5 142 ? 142.631 176.728 95.050  1.00 53.71 ? 130 GLN E C   1 
ATOM   7540 O O   . GLN E 5 142 ? 141.785 177.616 94.900  1.00 50.00 ? 130 GLN E O   1 
ATOM   7541 C CB  . GLN E 5 142 ? 140.994 174.903 95.602  1.00 45.52 ? 130 GLN E CB  1 
ATOM   7542 N N   . ALA E 5 143 ? 143.829 176.747 94.462  1.00 67.61 ? 131 ALA E N   1 
ATOM   7543 C CA  . ALA E 5 143 ? 144.278 177.915 93.711  1.00 65.85 ? 131 ALA E CA  1 
ATOM   7544 C C   . ALA E 5 143 ? 143.372 178.186 92.517  1.00 67.02 ? 131 ALA E C   1 
ATOM   7545 O O   . ALA E 5 143 ? 143.019 179.337 92.237  1.00 65.62 ? 131 ALA E O   1 
ATOM   7546 C CB  . ALA E 5 143 ? 145.725 177.716 93.256  1.00 64.05 ? 131 ALA E CB  1 
ATOM   7547 N N   . THR E 5 144 ? 142.982 177.134 91.802  1.00 68.85 ? 132 THR E N   1 
ATOM   7548 C CA  . THR E 5 144 ? 142.125 177.306 90.639  1.00 68.56 ? 132 THR E CA  1 
ATOM   7549 C C   . THR E 5 144 ? 140.750 177.806 91.062  1.00 67.44 ? 132 THR E C   1 
ATOM   7550 O O   . THR E 5 144 ? 140.199 177.375 92.078  1.00 62.17 ? 132 THR E O   1 
ATOM   7551 C CB  . THR E 5 144 ? 141.993 175.987 89.877  1.00 64.58 ? 132 THR E CB  1 
ATOM   7552 N N   . SER E 5 145 ? 140.206 178.732 90.273  1.00 69.95 ? 133 SER E N   1 
ATOM   7553 C CA  . SER E 5 145 ? 138.870 179.280 90.476  1.00 69.12 ? 133 SER E CA  1 
ATOM   7554 C C   . SER E 5 145 ? 137.953 178.992 89.300  1.00 69.12 ? 133 SER E C   1 
ATOM   7555 O O   . SER E 5 145 ? 136.793 178.613 89.501  1.00 68.76 ? 133 SER E O   1 
ATOM   7556 C CB  . SER E 5 145 ? 138.955 180.795 90.714  1.00 70.87 ? 133 SER E CB  1 
ATOM   7557 O OG  . SER E 5 145 ? 139.448 181.463 89.565  1.00 71.11 ? 133 SER E OG  1 
ATOM   7558 N N   . SER E 5 146 ? 138.441 179.166 88.074  1.00 70.60 ? 134 SER E N   1 
ATOM   7559 C CA  . SER E 5 146 ? 137.663 178.865 86.878  1.00 70.84 ? 134 SER E CA  1 
ATOM   7560 C C   . SER E 5 146 ? 138.631 178.456 85.781  1.00 72.43 ? 134 SER E C   1 
ATOM   7561 O O   . SER E 5 146 ? 139.485 179.255 85.384  1.00 74.31 ? 134 SER E O   1 
ATOM   7562 C CB  . SER E 5 146 ? 136.828 180.072 86.444  1.00 74.30 ? 134 SER E CB  1 
ATOM   7563 O OG  . SER E 5 146 ? 137.652 181.193 86.170  1.00 75.13 ? 134 SER E OG  1 
ATOM   7564 N N   . VAL E 5 147 ? 138.493 177.226 85.299  1.00 67.86 ? 135 VAL E N   1 
ATOM   7565 C CA  . VAL E 5 147 ? 139.378 176.646 84.297  1.00 72.75 ? 135 VAL E CA  1 
ATOM   7566 C C   . VAL E 5 147 ? 138.545 176.359 83.050  1.00 72.76 ? 135 VAL E C   1 
ATOM   7567 O O   . VAL E 5 147 ? 137.681 175.479 83.084  1.00 70.05 ? 135 VAL E O   1 
ATOM   7568 C CB  . VAL E 5 147 ? 140.049 175.358 84.802  1.00 70.17 ? 135 VAL E CB  1 
ATOM   7569 C CG1 . VAL E 5 147 ? 140.876 174.720 83.691  1.00 73.63 ? 135 VAL E CG1 1 
ATOM   7570 C CG2 . VAL E 5 147 ? 140.913 175.651 86.022  1.00 68.45 ? 135 VAL E CG2 1 
ATOM   7571 N N   . PRO E 5 148 ? 138.738 177.062 81.929  1.00 73.06 ? 136 PRO E N   1 
ATOM   7572 C CA  . PRO E 5 148 ? 138.031 176.657 80.706  1.00 69.50 ? 136 PRO E CA  1 
ATOM   7573 C C   . PRO E 5 148 ? 138.536 175.303 80.227  1.00 70.22 ? 136 PRO E C   1 
ATOM   7574 O O   . PRO E 5 148 ? 139.738 175.030 80.257  1.00 68.92 ? 136 PRO E O   1 
ATOM   7575 C CB  . PRO E 5 148 ? 138.358 177.775 79.709  1.00 71.29 ? 136 PRO E CB  1 
ATOM   7576 C CG  . PRO E 5 148 ? 139.616 178.362 80.195  1.00 72.57 ? 136 PRO E CG  1 
ATOM   7577 C CD  . PRO E 5 148 ? 139.583 178.248 81.688  1.00 72.89 ? 136 PRO E CD  1 
ATOM   7578 N N   . VAL E 5 149 ? 137.604 174.455 79.790  1.00 74.28 ? 137 VAL E N   1 
ATOM   7579 C CA  . VAL E 5 149 ? 137.910 173.090 79.384  1.00 75.89 ? 137 VAL E CA  1 
ATOM   7580 C C   . VAL E 5 149 ? 137.176 172.782 78.087  1.00 75.85 ? 137 VAL E C   1 
ATOM   7581 O O   . VAL E 5 149 ? 136.124 173.351 77.789  1.00 73.27 ? 137 VAL E O   1 
ATOM   7582 C CB  . VAL E 5 149 ? 137.528 172.055 80.469  1.00 71.60 ? 137 VAL E CB  1 
ATOM   7583 C CG1 . VAL E 5 149 ? 138.284 172.332 81.758  1.00 68.24 ? 137 VAL E CG1 1 
ATOM   7584 C CG2 . VAL E 5 149 ? 136.018 172.034 80.708  1.00 66.25 ? 137 VAL E CG2 1 
ATOM   7585 N N   . THR E 5 150 ? 137.757 171.855 77.312  1.00 83.01 ? 138 THR E N   1 
ATOM   7586 C CA  . THR E 5 150 ? 137.165 171.335 76.092  1.00 82.46 ? 138 THR E CA  1 
ATOM   7587 C C   . THR E 5 150 ? 136.587 169.944 76.351  1.00 78.83 ? 138 THR E C   1 
ATOM   7588 O O   . THR E 5 150 ? 137.117 169.218 77.199  1.00 75.25 ? 138 THR E O   1 
ATOM   7589 C CB  . THR E 5 150 ? 138.201 171.246 74.964  1.00 80.58 ? 138 THR E CB  1 
ATOM   7590 O OG1 . THR E 5 150 ? 139.352 170.525 75.422  1.00 80.74 ? 138 THR E OG1 1 
ATOM   7591 C CG2 . THR E 5 150 ? 138.626 172.637 74.515  1.00 78.68 ? 138 THR E CG2 1 
ATOM   7592 N N   . PRO E 5 151 ? 135.514 169.534 75.667  1.00 83.61 ? 139 PRO E N   1 
ATOM   7593 C CA  . PRO E 5 151 ? 135.027 168.161 75.853  1.00 83.62 ? 139 PRO E CA  1 
ATOM   7594 C C   . PRO E 5 151 ? 136.059 167.143 75.389  1.00 84.28 ? 139 PRO E C   1 
ATOM   7595 O O   . PRO E 5 151 ? 136.846 167.399 74.475  1.00 84.21 ? 139 PRO E O   1 
ATOM   7596 C CB  . PRO E 5 151 ? 133.758 168.108 74.993  1.00 83.00 ? 139 PRO E CB  1 
ATOM   7597 C CG  . PRO E 5 151 ? 133.368 169.519 74.782  1.00 83.92 ? 139 PRO E CG  1 
ATOM   7598 C CD  . PRO E 5 151 ? 134.645 170.286 74.743  1.00 84.47 ? 139 PRO E CD  1 
ATOM   7599 N N   . GLY E 5 152 ? 136.056 165.981 76.037  1.00 72.53 ? 140 GLY E N   1 
ATOM   7600 C CA  . GLY E 5 152 ? 136.982 164.930 75.671  1.00 72.46 ? 140 GLY E CA  1 
ATOM   7601 C C   . GLY E 5 152 ? 138.429 165.231 75.974  1.00 75.01 ? 140 GLY E C   1 
ATOM   7602 O O   . GLY E 5 152 ? 139.313 164.602 75.383  1.00 76.38 ? 140 GLY E O   1 
ATOM   7603 N N   . GLU E 5 153 ? 138.701 166.170 76.881  1.00 71.66 ? 141 GLU E N   1 
ATOM   7604 C CA  . GLU E 5 153 ? 140.055 166.587 77.220  1.00 73.67 ? 141 GLU E CA  1 
ATOM   7605 C C   . GLU E 5 153 ? 140.330 166.285 78.685  1.00 71.92 ? 141 GLU E C   1 
ATOM   7606 O O   . GLU E 5 153 ? 139.544 166.652 79.562  1.00 69.85 ? 141 GLU E O   1 
ATOM   7607 C CB  . GLU E 5 153 ? 140.255 168.083 76.952  1.00 71.86 ? 141 GLU E CB  1 
ATOM   7608 N N   . SER E 5 154 ? 141.453 165.620 78.941  1.00 68.61 ? 142 SER E N   1 
ATOM   7609 C CA  . SER E 5 154 ? 141.847 165.323 80.309  1.00 68.50 ? 142 SER E CA  1 
ATOM   7610 C C   . SER E 5 154 ? 142.191 166.606 81.056  1.00 66.67 ? 142 SER E C   1 
ATOM   7611 O O   . SER E 5 154 ? 142.805 167.526 80.508  1.00 69.17 ? 142 SER E O   1 
ATOM   7612 C CB  . SER E 5 154 ? 143.044 164.374 80.327  1.00 70.04 ? 142 SER E CB  1 
ATOM   7613 O OG  . SER E 5 154 ? 143.547 164.214 81.643  1.00 65.96 ? 142 SER E OG  1 
ATOM   7614 N N   . VAL E 5 155 ? 141.783 166.659 82.326  1.00 57.47 ? 143 VAL E N   1 
ATOM   7615 C CA  . VAL E 5 155 ? 142.015 167.809 83.190  1.00 61.53 ? 143 VAL E CA  1 
ATOM   7616 C C   . VAL E 5 155 ? 142.515 167.313 84.539  1.00 56.93 ? 143 VAL E C   1 
ATOM   7617 O O   . VAL E 5 155 ? 142.393 166.135 84.879  1.00 56.13 ? 143 VAL E O   1 
ATOM   7618 C CB  . VAL E 5 155 ? 140.748 168.678 83.378  1.00 60.14 ? 143 VAL E CB  1 
ATOM   7619 C CG1 . VAL E 5 155 ? 140.421 169.414 82.092  1.00 61.45 ? 143 VAL E CG1 1 
ATOM   7620 C CG2 . VAL E 5 155 ? 139.555 167.835 83.830  1.00 58.63 ? 143 VAL E CG2 1 
ATOM   7621 N N   . SER E 5 156 ? 143.097 168.236 85.302  1.00 49.85 ? 144 SER E N   1 
ATOM   7622 C CA  . SER E 5 156 ? 143.557 167.958 86.653  1.00 49.62 ? 144 SER E CA  1 
ATOM   7623 C C   . SER E 5 156 ? 143.147 169.105 87.563  1.00 52.48 ? 144 SER E C   1 
ATOM   7624 O O   . SER E 5 156 ? 143.136 170.269 87.153  1.00 54.57 ? 144 SER E O   1 
ATOM   7625 C CB  . SER E 5 156 ? 145.078 167.758 86.708  1.00 47.32 ? 144 SER E CB  1 
ATOM   7626 O OG  . SER E 5 156 ? 145.764 168.971 86.454  1.00 50.47 ? 144 SER E OG  1 
ATOM   7627 N N   . ILE E 5 157 ? 142.799 168.758 88.800  1.00 45.72 ? 145 ILE E N   1 
ATOM   7628 C CA  . ILE E 5 157 ? 142.422 169.719 89.830  1.00 48.20 ? 145 ILE E CA  1 
ATOM   7629 C C   . ILE E 5 157 ? 143.276 169.450 91.058  1.00 47.48 ? 145 ILE E C   1 
ATOM   7630 O O   . ILE E 5 157 ? 143.311 168.322 91.562  1.00 51.50 ? 145 ILE E O   1 
ATOM   7631 C CB  . ILE E 5 157 ? 140.922 169.631 90.182  1.00 43.87 ? 145 ILE E CB  1 
ATOM   7632 C CG1 . ILE E 5 157 ? 140.059 170.009 88.972  1.00 41.37 ? 145 ILE E CG1 1 
ATOM   7633 C CG2 . ILE E 5 157 ? 140.610 170.529 91.377  1.00 41.06 ? 145 ILE E CG2 1 
ATOM   7634 C CD1 . ILE E 5 157 ? 138.612 169.576 89.082  1.00 38.82 ? 145 ILE E CD1 1 
ATOM   7635 N N   . SER E 5 158 ? 143.959 170.484 91.538  1.00 41.69 ? 146 SER E N   1 
ATOM   7636 C CA  . SER E 5 158 ? 144.844 170.395 92.689  1.00 38.84 ? 146 SER E CA  1 
ATOM   7637 C C   . SER E 5 158 ? 144.240 171.135 93.874  1.00 41.50 ? 146 SER E C   1 
ATOM   7638 O O   . SER E 5 158 ? 143.508 172.115 93.717  1.00 51.23 ? 146 SER E O   1 
ATOM   7639 C CB  . SER E 5 158 ? 146.226 170.972 92.362  1.00 46.87 ? 146 SER E CB  1 
ATOM   7640 O OG  . SER E 5 158 ? 146.183 172.386 92.284  1.00 51.97 ? 146 SER E OG  1 
ATOM   7641 N N   . CYS E 5 159 ? 144.558 170.646 95.071  1.00 39.58 ? 147 CYS E N   1 
ATOM   7642 C CA  . CYS E 5 159 ? 144.098 171.248 96.318  1.00 46.66 ? 147 CYS E CA  1 
ATOM   7643 C C   . CYS E 5 159 ? 145.223 171.148 97.332  1.00 43.02 ? 147 CYS E C   1 
ATOM   7644 O O   . CYS E 5 159 ? 145.595 170.044 97.737  1.00 47.95 ? 147 CYS E O   1 
ATOM   7645 C CB  . CYS E 5 159 ? 142.836 170.554 96.841  1.00 47.86 ? 147 CYS E CB  1 
ATOM   7646 S SG  . CYS E 5 159 ? 142.353 171.036 98.521  1.00 62.30 ? 147 CYS E SG  1 
ATOM   7647 N N   . ARG E 5 160 ? 145.755 172.292 97.745  1.00 45.99 ? 148 ARG E N   1 
ATOM   7648 C CA  . ARG E 5 160 ? 146.885 172.331 98.657  1.00 45.95 ? 148 ARG E CA  1 
ATOM   7649 C C   . ARG E 5 160 ? 146.417 172.183 100.102 1.00 43.52 ? 148 ARG E C   1 
ATOM   7650 O O   . ARG E 5 160 ? 145.222 172.183 100.402 1.00 48.98 ? 148 ARG E O   1 
ATOM   7651 C CB  . ARG E 5 160 ? 147.669 173.631 98.476  1.00 51.97 ? 148 ARG E CB  1 
ATOM   7652 C CG  . ARG E 5 160 ? 148.515 173.676 97.203  1.00 51.68 ? 148 ARG E CG  1 
ATOM   7653 C CD  . ARG E 5 160 ? 149.687 174.653 97.302  1.00 52.87 ? 148 ARG E CD  1 
ATOM   7654 N NE  . ARG E 5 160 ? 150.599 174.333 98.396  1.00 51.55 ? 148 ARG E NE  1 
ATOM   7655 C CZ  . ARG E 5 160 ? 151.478 173.338 98.388  1.00 52.77 ? 148 ARG E CZ  1 
ATOM   7656 N NH1 . ARG E 5 160 ? 151.611 172.533 97.344  1.00 52.17 ? 148 ARG E NH1 1 
ATOM   7657 N NH2 . ARG E 5 160 ? 152.244 173.143 99.457  1.00 51.62 ? 148 ARG E NH2 1 
ATOM   7658 N N   . SER E 5 161 ? 147.388 172.048 101.004 1.00 37.78 ? 149 SER E N   1 
ATOM   7659 C CA  . SER E 5 161 ? 147.130 171.898 102.427 1.00 43.08 ? 149 SER E CA  1 
ATOM   7660 C C   . SER E 5 161 ? 148.173 172.686 103.205 1.00 48.84 ? 149 SER E C   1 
ATOM   7661 O O   . SER E 5 161 ? 149.234 173.035 102.683 1.00 53.39 ? 149 SER E O   1 
ATOM   7662 C CB  . SER E 5 161 ? 147.161 170.425 102.848 1.00 42.09 ? 149 SER E CB  1 
ATOM   7663 O OG  . SER E 5 161 ? 146.967 170.284 104.243 1.00 44.66 ? 149 SER E OG  1 
ATOM   7664 N N   . SER E 5 162 ? 147.855 172.970 104.468 1.00 47.67 ? 150 SER E N   1 
ATOM   7665 C CA  . SER E 5 162 ? 148.785 173.666 105.353 1.00 49.77 ? 150 SER E CA  1 
ATOM   7666 C C   . SER E 5 162 ? 149.772 172.690 105.986 1.00 49.92 ? 150 SER E C   1 
ATOM   7667 O O   . SER E 5 162 ? 150.988 172.839 105.829 1.00 50.98 ? 150 SER E O   1 
ATOM   7668 C CB  . SER E 5 162 ? 148.015 174.419 106.442 1.00 48.08 ? 150 SER E CB  1 
ATOM   7669 O OG  . SER E 5 162 ? 147.451 173.516 107.376 1.00 47.38 ? 150 SER E OG  1 
ATOM   7670 N N   . LYS E 5 163 ? 149.258 171.691 106.700 1.00 46.33 ? 151 LYS E N   1 
ATOM   7671 C CA  . LYS E 5 163 ? 150.056 170.661 107.345 1.00 48.39 ? 151 LYS E CA  1 
ATOM   7672 C C   . LYS E 5 163 ? 149.803 169.313 106.681 1.00 44.51 ? 151 LYS E C   1 
ATOM   7673 O O   . LYS E 5 163 ? 148.846 169.136 105.923 1.00 42.85 ? 151 LYS E O   1 
ATOM   7674 C CB  . LYS E 5 163 ? 149.749 170.597 108.848 1.00 43.50 ? 151 LYS E CB  1 
ATOM   7675 C CG  . LYS E 5 163 ? 148.405 169.983 109.212 1.00 46.66 ? 151 LYS E CG  1 
ATOM   7676 C CD  . LYS E 5 163 ? 148.115 170.106 110.702 1.00 49.12 ? 151 LYS E CD  1 
ATOM   7677 C CE  . LYS E 5 163 ? 149.018 169.213 111.534 1.00 45.40 ? 151 LYS E CE  1 
ATOM   7678 N NZ  . LYS E 5 163 ? 148.507 169.054 112.923 1.00 43.57 ? 151 LYS E NZ  1 
ATOM   7679 N N   . SER E 5 164 ? 150.684 168.362 106.974 1.00 39.18 ? 152 SER E N   1 
ATOM   7680 C CA  . SER E 5 164 ? 150.614 167.053 106.341 1.00 44.66 ? 152 SER E CA  1 
ATOM   7681 C C   . SER E 5 164 ? 149.382 166.294 106.816 1.00 45.87 ? 152 SER E C   1 
ATOM   7682 O O   . SER E 5 164 ? 149.061 166.292 108.008 1.00 42.36 ? 152 SER E O   1 
ATOM   7683 C CB  . SER E 5 164 ? 151.876 166.250 106.649 1.00 45.85 ? 152 SER E CB  1 
ATOM   7684 O OG  . SER E 5 164 ? 151.891 165.028 105.933 1.00 40.63 ? 152 SER E OG  1 
ATOM   7685 N N   . LEU E 5 165 ? 148.694 165.647 105.873 1.00 42.93 ? 153 LEU E N   1 
ATOM   7686 C CA  . LEU E 5 165 ? 147.544 164.803 106.171 1.00 36.32 ? 153 LEU E CA  1 
ATOM   7687 C C   . LEU E 5 165 ? 147.900 163.330 106.311 1.00 35.06 ? 153 LEU E C   1 
ATOM   7688 O O   . LEU E 5 165 ? 147.074 162.557 106.806 1.00 38.77 ? 153 LEU E O   1 
ATOM   7689 C CB  . LEU E 5 165 ? 146.485 164.950 105.072 1.00 37.24 ? 153 LEU E CB  1 
ATOM   7690 C CG  . LEU E 5 165 ? 145.734 166.284 104.981 1.00 34.16 ? 153 LEU E CG  1 
ATOM   7691 C CD1 . LEU E 5 165 ? 144.824 166.294 103.765 1.00 29.94 ? 153 LEU E CD1 1 
ATOM   7692 C CD2 . LEU E 5 165 ? 144.926 166.559 106.241 1.00 30.60 ? 153 LEU E CD2 1 
ATOM   7693 N N   . LEU E 5 166 ? 149.095 162.925 105.891 1.00 43.57 ? 154 LEU E N   1 
ATOM   7694 C CA  . LEU E 5 166 ? 149.488 161.527 105.978 1.00 39.66 ? 154 LEU E CA  1 
ATOM   7695 C C   . LEU E 5 166 ? 149.715 161.149 107.437 1.00 36.77 ? 154 LEU E C   1 
ATOM   7696 O O   . LEU E 5 166 ? 150.582 161.715 108.108 1.00 38.13 ? 154 LEU E O   1 
ATOM   7697 C CB  . LEU E 5 166 ? 150.756 161.296 105.156 1.00 43.96 ? 154 LEU E CB  1 
ATOM   7698 C CG  . LEU E 5 166 ? 151.060 159.878 104.659 1.00 39.77 ? 154 LEU E CG  1 
ATOM   7699 C CD1 . LEU E 5 166 ? 152.100 159.927 103.545 1.00 39.54 ? 154 LEU E CD1 1 
ATOM   7700 C CD2 . LEU E 5 166 ? 151.516 158.954 105.777 1.00 42.30 ? 154 LEU E CD2 1 
ATOM   7701 N N   . HIS E 5 167 ? 148.934 160.191 107.926 1.00 36.50 ? 155 HIS E N   1 
ATOM   7702 C CA  . HIS E 5 167 ? 148.990 159.785 109.320 1.00 41.39 ? 155 HIS E CA  1 
ATOM   7703 C C   . HIS E 5 167 ? 150.096 158.750 109.528 1.00 47.50 ? 155 HIS E C   1 
ATOM   7704 O O   . HIS E 5 167 ? 150.694 158.238 108.581 1.00 42.47 ? 155 HIS E O   1 
ATOM   7705 C CB  . HIS E 5 167 ? 147.634 159.239 109.764 1.00 38.28 ? 155 HIS E CB  1 
ATOM   7706 C CG  . HIS E 5 167 ? 147.369 159.395 111.229 1.00 39.77 ? 155 HIS E CG  1 
ATOM   7707 N ND1 . HIS E 5 167 ? 147.623 158.395 112.142 1.00 36.81 ? 155 HIS E ND1 1 
ATOM   7708 C CD2 . HIS E 5 167 ? 146.872 160.434 111.939 1.00 45.98 ? 155 HIS E CD2 1 
ATOM   7709 C CE1 . HIS E 5 167 ? 147.294 158.811 113.351 1.00 40.83 ? 155 HIS E CE1 1 
ATOM   7710 N NE2 . HIS E 5 167 ? 146.836 160.045 113.256 1.00 44.59 ? 155 HIS E NE2 1 
ATOM   7711 N N   . SER E 5 168 ? 150.378 158.444 110.796 1.00 51.95 ? 156 SER E N   1 
ATOM   7712 C CA  . SER E 5 168 ? 151.419 157.470 111.109 1.00 50.60 ? 156 SER E CA  1 
ATOM   7713 C C   . SER E 5 168 ? 151.058 156.084 110.587 1.00 47.82 ? 156 SER E C   1 
ATOM   7714 O O   . SER E 5 168 ? 151.920 155.365 110.069 1.00 45.63 ? 156 SER E O   1 
ATOM   7715 C CB  . SER E 5 168 ? 151.653 157.428 112.617 1.00 49.75 ? 156 SER E CB  1 
ATOM   7716 O OG  . SER E 5 168 ? 150.445 157.648 113.322 1.00 50.74 ? 156 SER E OG  1 
ATOM   7717 N N   . ASN E 5 169 ? 149.789 155.690 110.715 1.00 46.17 ? 157 ASN E N   1 
ATOM   7718 C CA  . ASN E 5 169 ? 149.364 154.375 110.248 1.00 48.15 ? 157 ASN E CA  1 
ATOM   7719 C C   . ASN E 5 169 ? 149.417 154.237 108.731 1.00 47.51 ? 157 ASN E C   1 
ATOM   7720 O O   . ASN E 5 169 ? 149.428 153.105 108.235 1.00 45.08 ? 157 ASN E O   1 
ATOM   7721 C CB  . ASN E 5 169 ? 147.948 154.063 110.746 1.00 44.27 ? 157 ASN E CB  1 
ATOM   7722 C CG  . ASN E 5 169 ? 146.928 155.106 110.322 1.00 45.53 ? 157 ASN E CG  1 
ATOM   7723 O OD1 . ASN E 5 169 ? 146.747 155.372 109.136 1.00 41.26 ? 157 ASN E OD1 1 
ATOM   7724 N ND2 . ASN E 5 169 ? 146.249 155.697 111.297 1.00 47.61 ? 157 ASN E ND2 1 
ATOM   7725 N N   . GLY E 5 170 ? 149.442 155.346 107.993 1.00 48.83 ? 158 GLY E N   1 
ATOM   7726 C CA  . GLY E 5 170 ? 149.585 155.330 106.551 1.00 49.48 ? 158 GLY E CA  1 
ATOM   7727 C C   . GLY E 5 170 ? 148.364 155.753 105.761 1.00 43.64 ? 158 GLY E C   1 
ATOM   7728 O O   . GLY E 5 170 ? 148.396 155.675 104.527 1.00 40.11 ? 158 GLY E O   1 
ATOM   7729 N N   . ASN E 5 171 ? 147.299 156.200 106.418 1.00 31.64 ? 159 ASN E N   1 
ATOM   7730 C CA  . ASN E 5 171 ? 146.098 156.672 105.743 1.00 31.37 ? 159 ASN E CA  1 
ATOM   7731 C C   . ASN E 5 171 ? 146.170 158.185 105.601 1.00 37.29 ? 159 ASN E C   1 
ATOM   7732 O O   . ASN E 5 171 ? 146.406 158.891 106.586 1.00 48.40 ? 159 ASN E O   1 
ATOM   7733 C CB  . ASN E 5 171 ? 144.840 156.280 106.521 1.00 30.50 ? 159 ASN E CB  1 
ATOM   7734 C CG  . ASN E 5 171 ? 144.153 155.059 105.943 1.00 38.58 ? 159 ASN E CG  1 
ATOM   7735 O OD1 . ASN E 5 171 ? 143.634 155.094 104.828 1.00 39.06 ? 159 ASN E OD1 1 
ATOM   7736 N ND2 . ASN E 5 171 ? 144.141 153.971 106.703 1.00 41.44 ? 159 ASN E ND2 1 
ATOM   7737 N N   . THR E 5 172 ? 145.974 158.676 104.380 1.00 31.39 ? 160 THR E N   1 
ATOM   7738 C CA  . THR E 5 172 ? 145.887 160.106 104.109 1.00 33.42 ? 160 THR E CA  1 
ATOM   7739 C C   . THR E 5 172 ? 144.408 160.462 104.068 1.00 29.47 ? 160 THR E C   1 
ATOM   7740 O O   . THR E 5 172 ? 143.663 159.941 103.234 1.00 34.86 ? 160 THR E O   1 
ATOM   7741 C CB  . THR E 5 172 ? 146.579 160.468 102.797 1.00 36.30 ? 160 THR E CB  1 
ATOM   7742 O OG1 . THR E 5 172 ? 148.000 160.390 102.966 1.00 41.87 ? 160 THR E OG1 1 
ATOM   7743 C CG2 . THR E 5 172 ? 146.218 161.881 102.377 1.00 31.73 ? 160 THR E CG2 1 
ATOM   7744 N N   . TYR E 5 173 ? 143.987 161.351 104.963 1.00 23.09 ? 161 TYR E N   1 
ATOM   7745 C CA  . TYR E 5 173 ? 142.572 161.616 105.199 1.00 27.40 ? 161 TYR E CA  1 
ATOM   7746 C C   . TYR E 5 173 ? 142.159 162.840 104.393 1.00 24.24 ? 161 TYR E C   1 
ATOM   7747 O O   . TYR E 5 173 ? 142.151 163.959 104.913 1.00 20.62 ? 161 TYR E O   1 
ATOM   7748 C CB  . TYR E 5 173 ? 142.301 161.824 106.687 1.00 26.77 ? 161 TYR E CB  1 
ATOM   7749 C CG  . TYR E 5 173 ? 142.564 160.603 107.543 1.00 30.18 ? 161 TYR E CG  1 
ATOM   7750 C CD1 . TYR E 5 173 ? 143.856 160.175 107.803 1.00 33.82 ? 161 TYR E CD1 1 
ATOM   7751 C CD2 . TYR E 5 173 ? 141.521 159.902 108.119 1.00 26.52 ? 161 TYR E CD2 1 
ATOM   7752 C CE1 . TYR E 5 173 ? 144.099 159.071 108.582 1.00 39.42 ? 161 TYR E CE1 1 
ATOM   7753 C CE2 . TYR E 5 173 ? 141.755 158.795 108.901 1.00 27.93 ? 161 TYR E CE2 1 
ATOM   7754 C CZ  . TYR E 5 173 ? 143.046 158.383 109.130 1.00 37.46 ? 161 TYR E CZ  1 
ATOM   7755 O OH  . TYR E 5 173 ? 143.291 157.280 109.916 1.00 40.36 ? 161 TYR E OH  1 
ATOM   7756 N N   . LEU E 5 174 ? 141.804 162.624 103.129 1.00 25.58 ? 162 LEU E N   1 
ATOM   7757 C CA  . LEU E 5 174 ? 141.403 163.704 102.241 1.00 19.15 ? 162 LEU E CA  1 
ATOM   7758 C C   . LEU E 5 174 ? 140.306 163.197 101.322 1.00 17.17 ? 162 LEU E C   1 
ATOM   7759 O O   . LEU E 5 174 ? 140.346 162.048 100.876 1.00 29.98 ? 162 LEU E O   1 
ATOM   7760 C CB  . LEU E 5 174 ? 142.587 164.223 101.426 1.00 21.79 ? 162 LEU E CB  1 
ATOM   7761 C CG  . LEU E 5 174 ? 142.273 165.418 100.528 1.00 26.11 ? 162 LEU E CG  1 
ATOM   7762 C CD1 . LEU E 5 174 ? 143.268 166.533 100.748 1.00 32.96 ? 162 LEU E CD1 1 
ATOM   7763 C CD2 . LEU E 5 174 ? 142.272 164.992 99.071  1.00 27.74 ? 162 LEU E CD2 1 
ATOM   7764 N N   . TYR E 5 175 ? 139.338 164.065 101.043 1.00 5.05  ? 163 TYR E N   1 
ATOM   7765 C CA  . TYR E 5 175 ? 138.115 163.699 100.349 1.00 12.00 ? 163 TYR E CA  1 
ATOM   7766 C C   . TYR E 5 175 ? 137.896 164.652 99.185  1.00 17.68 ? 163 TYR E C   1 
ATOM   7767 O O   . TYR E 5 175 ? 138.382 165.784 99.197  1.00 20.89 ? 163 TYR E O   1 
ATOM   7768 C CB  . TYR E 5 175 ? 136.905 163.741 101.301 1.00 21.40 ? 163 TYR E CB  1 
ATOM   7769 C CG  . TYR E 5 175 ? 136.920 162.667 102.367 1.00 15.51 ? 163 TYR E CG  1 
ATOM   7770 C CD1 . TYR E 5 175 ? 137.827 162.712 103.413 1.00 17.05 ? 163 TYR E CD1 1 
ATOM   7771 C CD2 . TYR E 5 175 ? 136.025 161.614 102.331 1.00 14.98 ? 163 TYR E CD2 1 
ATOM   7772 C CE1 . TYR E 5 175 ? 137.852 161.741 104.379 1.00 15.29 ? 163 TYR E CE1 1 
ATOM   7773 C CE2 . TYR E 5 175 ? 136.040 160.638 103.301 1.00 19.78 ? 163 TYR E CE2 1 
ATOM   7774 C CZ  . TYR E 5 175 ? 136.960 160.706 104.320 1.00 15.00 ? 163 TYR E CZ  1 
ATOM   7775 O OH  . TYR E 5 175 ? 136.988 159.742 105.295 1.00 24.86 ? 163 TYR E OH  1 
ATOM   7776 N N   . TRP E 5 176 ? 137.171 164.179 98.174  1.00 15.77 ? 164 TRP E N   1 
ATOM   7777 C CA  . TRP E 5 176 ? 136.796 164.982 97.016  1.00 18.39 ? 164 TRP E CA  1 
ATOM   7778 C C   . TRP E 5 176 ? 135.292 164.883 96.810  1.00 17.68 ? 164 TRP E C   1 
ATOM   7779 O O   . TRP E 5 176 ? 134.750 163.779 96.705  1.00 29.03 ? 164 TRP E O   1 
ATOM   7780 C CB  . TRP E 5 176 ? 137.535 164.522 95.757  1.00 30.50 ? 164 TRP E CB  1 
ATOM   7781 C CG  . TRP E 5 176 ? 138.985 164.889 95.749  1.00 30.09 ? 164 TRP E CG  1 
ATOM   7782 C CD1 . TRP E 5 176 ? 140.036 164.095 96.102  1.00 27.44 ? 164 TRP E CD1 1 
ATOM   7783 C CD2 . TRP E 5 176 ? 139.546 166.151 95.374  1.00 26.09 ? 164 TRP E CD2 1 
ATOM   7784 N NE1 . TRP E 5 176 ? 141.215 164.783 95.969  1.00 25.47 ? 164 TRP E NE1 1 
ATOM   7785 C CE2 . TRP E 5 176 ? 140.940 166.049 95.524  1.00 25.85 ? 164 TRP E CE2 1 
ATOM   7786 C CE3 . TRP E 5 176 ? 139.004 167.358 94.926  1.00 28.37 ? 164 TRP E CE3 1 
ATOM   7787 C CZ2 . TRP E 5 176 ? 141.797 167.105 95.242  1.00 33.26 ? 164 TRP E CZ2 1 
ATOM   7788 C CZ3 . TRP E 5 176 ? 139.857 168.404 94.647  1.00 24.94 ? 164 TRP E CZ3 1 
ATOM   7789 C CH2 . TRP E 5 176 ? 141.237 168.272 94.806  1.00 28.90 ? 164 TRP E CH2 1 
ATOM   7790 N N   . PHE E 5 177 ? 134.629 166.037 96.747  1.00 15.38 ? 165 PHE E N   1 
ATOM   7791 C CA  . PHE E 5 177 ? 133.184 166.127 96.590  1.00 19.27 ? 165 PHE E CA  1 
ATOM   7792 C C   . PHE E 5 177 ? 132.864 166.923 95.334  1.00 25.48 ? 165 PHE E C   1 
ATOM   7793 O O   . PHE E 5 177 ? 133.597 167.849 94.978  1.00 43.87 ? 165 PHE E O   1 
ATOM   7794 C CB  . PHE E 5 177 ? 132.538 166.798 97.804  1.00 26.68 ? 165 PHE E CB  1 
ATOM   7795 C CG  . PHE E 5 177 ? 132.755 166.059 99.089  1.00 21.01 ? 165 PHE E CG  1 
ATOM   7796 C CD1 . PHE E 5 177 ? 131.964 164.978 99.421  1.00 18.28 ? 165 PHE E CD1 1 
ATOM   7797 C CD2 . PHE E 5 177 ? 133.758 166.438 99.957  1.00 24.61 ? 165 PHE E CD2 1 
ATOM   7798 C CE1 . PHE E 5 177 ? 132.165 164.297 100.595 1.00 18.00 ? 165 PHE E CE1 1 
ATOM   7799 C CE2 . PHE E 5 177 ? 133.961 165.759 101.134 1.00 15.77 ? 165 PHE E CE2 1 
ATOM   7800 C CZ  . PHE E 5 177 ? 133.165 164.686 101.452 1.00 20.71 ? 165 PHE E CZ  1 
ATOM   7801 N N   . LEU E 5 178 ? 131.770 166.558 94.668  1.00 18.40 ? 166 LEU E N   1 
ATOM   7802 C CA  . LEU E 5 178 ? 131.341 167.189 93.427  1.00 18.49 ? 166 LEU E CA  1 
ATOM   7803 C C   . LEU E 5 178 ? 129.884 167.610 93.524  1.00 24.35 ? 166 LEU E C   1 
ATOM   7804 O O   . LEU E 5 178 ? 129.026 166.809 93.898  1.00 35.64 ? 166 LEU E O   1 
ATOM   7805 C CB  . LEU E 5 178 ? 131.510 166.239 92.248  1.00 20.36 ? 166 LEU E CB  1 
ATOM   7806 C CG  . LEU E 5 178 ? 131.096 166.794 90.882  1.00 28.07 ? 166 LEU E CG  1 
ATOM   7807 C CD1 . LEU E 5 178 ? 132.262 166.774 89.950  1.00 32.64 ? 166 LEU E CD1 1 
ATOM   7808 C CD2 . LEU E 5 178 ? 129.952 166.008 90.305  1.00 29.76 ? 166 LEU E CD2 1 
ATOM   7809 N N   . GLN E 5 179 ? 129.611 168.854 93.131  1.00 25.16 ? 167 GLN E N   1 
ATOM   7810 C CA  . GLN E 5 179 ? 128.269 169.429 93.148  1.00 29.51 ? 167 GLN E CA  1 
ATOM   7811 C C   . GLN E 5 179 ? 127.900 169.873 91.741  1.00 35.21 ? 167 GLN E C   1 
ATOM   7812 O O   . GLN E 5 179 ? 128.499 170.815 91.212  1.00 35.38 ? 167 GLN E O   1 
ATOM   7813 C CB  . GLN E 5 179 ? 128.198 170.615 94.118  1.00 26.69 ? 167 GLN E CB  1 
ATOM   7814 C CG  . GLN E 5 179 ? 126.959 171.498 93.969  1.00 27.63 ? 167 GLN E CG  1 
ATOM   7815 C CD  . GLN E 5 179 ? 126.784 172.467 95.123  1.00 36.99 ? 167 GLN E CD  1 
ATOM   7816 O OE1 . GLN E 5 179 ? 127.437 172.346 96.157  1.00 36.64 ? 167 GLN E OE1 1 
ATOM   7817 N NE2 . GLN E 5 179 ? 125.897 173.438 94.947  1.00 32.83 ? 167 GLN E NE2 1 
ATOM   7818 N N   . ARG E 5 180 ? 126.912 169.213 91.143  1.00 39.53 ? 168 ARG E N   1 
ATOM   7819 C CA  . ARG E 5 180 ? 126.353 169.703 89.896  1.00 39.54 ? 168 ARG E CA  1 
ATOM   7820 C C   . ARG E 5 180 ? 125.555 170.977 90.158  1.00 43.46 ? 168 ARG E C   1 
ATOM   7821 O O   . ARG E 5 180 ? 125.217 171.277 91.305  1.00 45.50 ? 168 ARG E O   1 
ATOM   7822 C CB  . ARG E 5 180 ? 125.446 168.657 89.251  1.00 40.01 ? 168 ARG E CB  1 
ATOM   7823 C CG  . ARG E 5 180 ? 126.148 167.539 88.488  1.00 33.78 ? 168 ARG E CG  1 
ATOM   7824 C CD  . ARG E 5 180 ? 126.542 166.377 89.377  1.00 39.75 ? 168 ARG E CD  1 
ATOM   7825 N NE  . ARG E 5 180 ? 127.394 165.429 88.667  1.00 41.50 ? 168 ARG E NE  1 
ATOM   7826 C CZ  . ARG E 5 180 ? 127.583 164.160 89.012  1.00 39.47 ? 168 ARG E CZ  1 
ATOM   7827 N NH1 . ARG E 5 180 ? 126.984 163.626 90.064  1.00 38.22 ? 168 ARG E NH1 1 
ATOM   7828 N NH2 . ARG E 5 180 ? 128.402 163.407 88.283  1.00 38.05 ? 168 ARG E NH2 1 
ATOM   7829 N N   . PRO E 5 181 ? 125.257 171.760 89.119  1.00 49.61 ? 169 PRO E N   1 
ATOM   7830 C CA  . PRO E 5 181 ? 124.393 172.931 89.322  1.00 50.03 ? 169 PRO E CA  1 
ATOM   7831 C C   . PRO E 5 181 ? 123.018 172.517 89.824  1.00 50.17 ? 169 PRO E C   1 
ATOM   7832 O O   . PRO E 5 181 ? 122.398 171.591 89.296  1.00 49.91 ? 169 PRO E O   1 
ATOM   7833 C CB  . PRO E 5 181 ? 124.318 173.570 87.930  1.00 53.78 ? 169 PRO E CB  1 
ATOM   7834 C CG  . PRO E 5 181 ? 125.472 173.019 87.180  1.00 53.81 ? 169 PRO E CG  1 
ATOM   7835 C CD  . PRO E 5 181 ? 125.697 171.647 87.717  1.00 53.34 ? 169 PRO E CD  1 
ATOM   7836 N N   . GLY E 5 182 ? 122.542 173.217 90.852  1.00 50.74 ? 170 GLY E N   1 
ATOM   7837 C CA  . GLY E 5 182 ? 121.236 172.921 91.416  1.00 52.15 ? 170 GLY E CA  1 
ATOM   7838 C C   . GLY E 5 182 ? 121.108 171.520 91.969  1.00 53.45 ? 170 GLY E C   1 
ATOM   7839 O O   . GLY E 5 182 ? 120.064 170.884 91.792  1.00 53.08 ? 170 GLY E O   1 
ATOM   7840 N N   . GLN E 5 183 ? 122.146 171.019 92.635  1.00 45.11 ? 171 GLN E N   1 
ATOM   7841 C CA  . GLN E 5 183 ? 122.157 169.665 93.168  1.00 43.32 ? 171 GLN E CA  1 
ATOM   7842 C C   . GLN E 5 183 ? 122.997 169.642 94.436  1.00 46.85 ? 171 GLN E C   1 
ATOM   7843 O O   . GLN E 5 183 ? 123.830 170.520 94.672  1.00 46.17 ? 171 GLN E O   1 
ATOM   7844 C CB  . GLN E 5 183 ? 122.703 168.668 92.138  1.00 33.51 ? 171 GLN E CB  1 
ATOM   7845 C CG  . GLN E 5 183 ? 122.146 167.263 92.272  1.00 41.69 ? 171 GLN E CG  1 
ATOM   7846 C CD  . GLN E 5 183 ? 123.049 166.217 91.648  1.00 47.07 ? 171 GLN E CD  1 
ATOM   7847 O OE1 . GLN E 5 183 ? 123.935 165.671 92.307  1.00 43.12 ? 171 GLN E OE1 1 
ATOM   7848 N NE2 . GLN E 5 183 ? 122.828 165.932 90.370  1.00 47.36 ? 171 GLN E NE2 1 
ATOM   7849 N N   . SER E 5 184 ? 122.758 168.626 95.271  1.00 34.92 ? 172 SER E N   1 
ATOM   7850 C CA  . SER E 5 184 ? 123.573 168.453 96.462  1.00 25.40 ? 172 SER E CA  1 
ATOM   7851 C C   . SER E 5 184 ? 124.906 167.806 96.098  1.00 22.41 ? 172 SER E C   1 
ATOM   7852 O O   . SER E 5 184 ? 124.984 167.045 95.130  1.00 34.11 ? 172 SER E O   1 
ATOM   7853 C CB  . SER E 5 184 ? 122.849 167.580 97.479  1.00 33.90 ? 172 SER E CB  1 
ATOM   7854 O OG  . SER E 5 184 ? 122.339 166.410 96.865  1.00 33.55 ? 172 SER E OG  1 
ATOM   7855 N N   . PRO E 5 185 ? 125.988 168.062 96.832  1.00 7.75  ? 173 PRO E N   1 
ATOM   7856 C CA  . PRO E 5 185 ? 127.256 167.412 96.499  1.00 23.03 ? 173 PRO E CA  1 
ATOM   7857 C C   . PRO E 5 185 ? 127.242 165.938 96.866  1.00 24.94 ? 173 PRO E C   1 
ATOM   7858 O O   . PRO E 5 185 ? 126.411 165.470 97.645  1.00 39.96 ? 173 PRO E O   1 
ATOM   7859 C CB  . PRO E 5 185 ? 128.288 168.184 97.326  1.00 23.29 ? 173 PRO E CB  1 
ATOM   7860 C CG  . PRO E 5 185 ? 127.541 168.721 98.439  1.00 21.64 ? 173 PRO E CG  1 
ATOM   7861 C CD  . PRO E 5 185 ? 126.151 168.999 97.955  1.00 23.54 ? 173 PRO E CD  1 
ATOM   7862 N N   . GLN E 5 186 ? 128.180 165.201 96.274  1.00 15.78 ? 174 GLN E N   1 
ATOM   7863 C CA  . GLN E 5 186 ? 128.312 163.770 96.500  1.00 19.34 ? 174 GLN E CA  1 
ATOM   7864 C C   . GLN E 5 186 ? 129.782 163.395 96.572  1.00 16.33 ? 174 GLN E C   1 
ATOM   7865 O O   . GLN E 5 186 ? 130.641 164.075 96.008  1.00 27.65 ? 174 GLN E O   1 
ATOM   7866 C CB  . GLN E 5 186 ? 127.628 162.961 95.393  1.00 33.81 ? 174 GLN E CB  1 
ATOM   7867 C CG  . GLN E 5 186 ? 128.184 163.206 93.997  1.00 28.85 ? 174 GLN E CG  1 
ATOM   7868 C CD  . GLN E 5 186 ? 127.431 162.443 92.933  1.00 30.82 ? 174 GLN E CD  1 
ATOM   7869 O OE1 . GLN E 5 186 ? 128.009 161.628 92.215  1.00 29.72 ? 174 GLN E OE1 1 
ATOM   7870 N NE2 . GLN E 5 186 ? 126.135 162.704 92.820  1.00 29.20 ? 174 GLN E NE2 1 
ATOM   7871 N N   . LEU E 5 187 ? 130.061 162.295 97.264  1.00 11.03 ? 175 LEU E N   1 
ATOM   7872 C CA  . LEU E 5 187 ? 131.428 161.816 97.387  1.00 18.21 ? 175 LEU E CA  1 
ATOM   7873 C C   . LEU E 5 187 ? 131.939 161.307 96.046  1.00 24.39 ? 175 LEU E C   1 
ATOM   7874 O O   . LEU E 5 187 ? 131.210 160.653 95.295  1.00 27.34 ? 175 LEU E O   1 
ATOM   7875 C CB  . LEU E 5 187 ? 131.500 160.702 98.431  1.00 14.81 ? 175 LEU E CB  1 
ATOM   7876 C CG  . LEU E 5 187 ? 132.879 160.153 98.799  1.00 15.44 ? 175 LEU E CG  1 
ATOM   7877 C CD1 . LEU E 5 187 ? 133.670 161.171 99.589  1.00 18.24 ? 175 LEU E CD1 1 
ATOM   7878 C CD2 . LEU E 5 187 ? 132.737 158.865 99.585  1.00 15.95 ? 175 LEU E CD2 1 
ATOM   7879 N N   . LEU E 5 188 ? 133.199 161.628 95.744  1.00 29.18 ? 176 LEU E N   1 
ATOM   7880 C CA  . LEU E 5 188 ? 133.908 161.066 94.598  1.00 22.42 ? 176 LEU E CA  1 
ATOM   7881 C C   . LEU E 5 188 ? 135.068 160.187 95.040  1.00 24.67 ? 176 LEU E C   1 
ATOM   7882 O O   . LEU E 5 188 ? 135.125 159.016 94.656  1.00 30.72 ? 176 LEU E O   1 
ATOM   7883 C CB  . LEU E 5 188 ? 134.422 162.180 93.675  1.00 21.95 ? 176 LEU E CB  1 
ATOM   7884 C CG  . LEU E 5 188 ? 133.446 163.086 92.910  1.00 23.10 ? 176 LEU E CG  1 
ATOM   7885 C CD1 . LEU E 5 188 ? 134.163 163.715 91.722  1.00 32.82 ? 176 LEU E CD1 1 
ATOM   7886 C CD2 . LEU E 5 188 ? 132.191 162.362 92.440  1.00 29.13 ? 176 LEU E CD2 1 
ATOM   7887 N N   . ILE E 5 189 ? 135.993 160.721 95.834  1.00 21.98 ? 177 ILE E N   1 
ATOM   7888 C CA  . ILE E 5 189 ? 137.160 159.990 96.315  1.00 20.05 ? 177 ILE E CA  1 
ATOM   7889 C C   . ILE E 5 189 ? 137.264 160.206 97.814  1.00 12.03 ? 177 ILE E C   1 
ATOM   7890 O O   . ILE E 5 189 ? 137.182 161.345 98.283  1.00 16.47 ? 177 ILE E O   1 
ATOM   7891 C CB  . ILE E 5 189 ? 138.452 160.447 95.607  1.00 26.49 ? 177 ILE E CB  1 
ATOM   7892 C CG1 . ILE E 5 189 ? 138.441 159.954 94.158  1.00 23.80 ? 177 ILE E CG1 1 
ATOM   7893 C CG2 . ILE E 5 189 ? 139.697 159.957 96.373  1.00 28.75 ? 177 ILE E CG2 1 
ATOM   7894 C CD1 . ILE E 5 189 ? 139.552 160.494 93.299  1.00 27.76 ? 177 ILE E CD1 1 
ATOM   7895 N N   . TYR E 5 190 ? 137.440 159.119 98.563  1.00 6.09  ? 178 TYR E N   1 
ATOM   7896 C CA  . TYR E 5 190 ? 137.673 159.176 99.998  1.00 13.02 ? 178 TYR E CA  1 
ATOM   7897 C C   . TYR E 5 190 ? 139.064 158.645 100.306 1.00 18.60 ? 178 TYR E C   1 
ATOM   7898 O O   . TYR E 5 190 ? 139.490 157.626 99.755  1.00 26.85 ? 178 TYR E O   1 
ATOM   7899 C CB  . TYR E 5 190 ? 136.613 158.389 100.784 1.00 8.68  ? 178 TYR E CB  1 
ATOM   7900 C CG  . TYR E 5 190 ? 136.507 156.916 100.468 1.00 17.87 ? 178 TYR E CG  1 
ATOM   7901 C CD1 . TYR E 5 190 ? 135.709 156.462 99.431  1.00 28.45 ? 178 TYR E CD1 1 
ATOM   7902 C CD2 . TYR E 5 190 ? 137.175 155.976 101.238 1.00 16.17 ? 178 TYR E CD2 1 
ATOM   7903 C CE1 . TYR E 5 190 ? 135.602 155.115 99.152  1.00 19.62 ? 178 TYR E CE1 1 
ATOM   7904 C CE2 . TYR E 5 190 ? 137.072 154.628 100.969 1.00 12.53 ? 178 TYR E CE2 1 
ATOM   7905 C CZ  . TYR E 5 190 ? 136.285 154.203 99.925  1.00 14.10 ? 178 TYR E CZ  1 
ATOM   7906 O OH  . TYR E 5 190 ? 136.181 152.860 99.651  1.00 12.16 ? 178 TYR E OH  1 
ATOM   7907 N N   . ARG E 5 191 ? 139.767 159.355 101.186 1.00 17.18 ? 179 ARG E N   1 
ATOM   7908 C CA  . ARG E 5 191 ? 141.141 159.039 101.566 1.00 13.08 ? 179 ARG E CA  1 
ATOM   7909 C C   . ARG E 5 191 ? 142.085 159.056 100.363 1.00 20.95 ? 179 ARG E C   1 
ATOM   7910 O O   . ARG E 5 191 ? 143.013 158.250 100.272 1.00 30.72 ? 179 ARG E O   1 
ATOM   7911 C CB  . ARG E 5 191 ? 141.213 157.699 102.305 1.00 18.30 ? 179 ARG E CB  1 
ATOM   7912 C CG  . ARG E 5 191 ? 140.632 157.760 103.703 1.00 20.10 ? 179 ARG E CG  1 
ATOM   7913 C CD  . ARG E 5 191 ? 141.009 156.540 104.513 1.00 26.42 ? 179 ARG E CD  1 
ATOM   7914 N NE  . ARG E 5 191 ? 139.929 156.114 105.395 1.00 24.54 ? 179 ARG E NE  1 
ATOM   7915 C CZ  . ARG E 5 191 ? 138.911 155.340 105.043 1.00 19.20 ? 179 ARG E CZ  1 
ATOM   7916 N NH1 . ARG E 5 191 ? 138.776 154.880 103.809 1.00 23.42 ? 179 ARG E NH1 1 
ATOM   7917 N NH2 . ARG E 5 191 ? 137.999 155.019 105.955 1.00 18.25 ? 179 ARG E NH2 1 
ATOM   7918 N N   . MET E 5 192 ? 141.830 159.963 99.414  1.00 17.83 ? 180 MET E N   1 
ATOM   7919 C CA  . MET E 5 192 ? 142.768 160.411 98.381  1.00 19.94 ? 180 MET E CA  1 
ATOM   7920 C C   . MET E 5 192 ? 143.023 159.392 97.268  1.00 24.57 ? 180 MET E C   1 
ATOM   7921 O O   . MET E 5 192 ? 143.540 159.772 96.212  1.00 35.10 ? 180 MET E O   1 
ATOM   7922 C CB  . MET E 5 192 ? 144.103 160.835 99.047  1.00 27.00 ? 180 MET E CB  1 
ATOM   7923 C CG  . MET E 5 192 ? 145.332 161.078 98.151  1.00 30.75 ? 180 MET E CG  1 
ATOM   7924 S SD  . MET E 5 192 ? 146.833 161.138 99.136  1.00 40.40 ? 180 MET E SD  1 
ATOM   7925 C CE  . MET E 5 192 ? 147.924 161.996 98.014  1.00 29.75 ? 180 MET E CE  1 
ATOM   7926 N N   . SER E 5 193 ? 142.617 158.135 97.437  1.00 25.39 ? 181 SER E N   1 
ATOM   7927 C CA  . SER E 5 193 ? 142.858 157.103 96.428  1.00 17.60 ? 181 SER E CA  1 
ATOM   7928 C C   . SER E 5 193 ? 141.625 156.274 96.114  1.00 18.52 ? 181 SER E C   1 
ATOM   7929 O O   . SER E 5 193 ? 141.419 155.906 94.956  1.00 21.85 ? 181 SER E O   1 
ATOM   7930 C CB  . SER E 5 193 ? 143.997 156.183 96.890  1.00 19.96 ? 181 SER E CB  1 
ATOM   7931 O OG  . SER E 5 193 ? 143.839 155.815 98.247  1.00 29.40 ? 181 SER E OG  1 
ATOM   7932 N N   . ASN E 5 194 ? 140.800 155.979 97.111  1.00 9.48  ? 182 ASN E N   1 
ATOM   7933 C CA  . ASN E 5 194 ? 139.687 155.066 96.931  1.00 11.37 ? 182 ASN E CA  1 
ATOM   7934 C C   . ASN E 5 194 ? 138.506 155.782 96.286  1.00 14.07 ? 182 ASN E C   1 
ATOM   7935 O O   . ASN E 5 194 ? 138.201 156.934 96.593  1.00 13.03 ? 182 ASN E O   1 
ATOM   7936 C CB  . ASN E 5 194 ? 139.275 154.463 98.271  1.00 21.86 ? 182 ASN E CB  1 
ATOM   7937 C CG  . ASN E 5 194 ? 140.463 154.072 99.126  1.00 15.05 ? 182 ASN E CG  1 
ATOM   7938 O OD1 . ASN E 5 194 ? 140.909 154.841 99.975  1.00 4.45  ? 182 ASN E OD1 1 
ATOM   7939 N ND2 . ASN E 5 194 ? 140.977 152.870 98.909  1.00 25.29 ? 182 ASN E ND2 1 
ATOM   7940 N N   . LEU E 5 195 ? 137.831 155.074 95.387  1.00 22.97 ? 183 LEU E N   1 
ATOM   7941 C CA  . LEU E 5 195 ? 136.687 155.595 94.657  1.00 24.08 ? 183 LEU E CA  1 
ATOM   7942 C C   . LEU E 5 195 ? 135.404 155.302 95.422  1.00 22.99 ? 183 LEU E C   1 
ATOM   7943 O O   . LEU E 5 195 ? 135.298 154.295 96.127  1.00 26.48 ? 183 LEU E O   1 
ATOM   7944 C CB  . LEU E 5 195 ? 136.595 154.968 93.259  1.00 26.57 ? 183 LEU E CB  1 
ATOM   7945 C CG  . LEU E 5 195 ? 137.339 155.569 92.061  1.00 26.72 ? 183 LEU E CG  1 
ATOM   7946 C CD1 . LEU E 5 195 ? 136.847 154.902 90.790  1.00 29.09 ? 183 LEU E CD1 1 
ATOM   7947 C CD2 . LEU E 5 195 ? 137.170 157.073 91.945  1.00 32.13 ? 183 LEU E CD2 1 
ATOM   7948 N N   . ALA E 5 196 ? 134.427 156.191 95.274  1.00 17.28 ? 184 ALA E N   1 
ATOM   7949 C CA  . ALA E 5 196 ? 133.114 155.988 95.868  1.00 24.88 ? 184 ALA E CA  1 
ATOM   7950 C C   . ALA E 5 196 ? 132.332 154.990 95.016  1.00 31.94 ? 184 ALA E C   1 
ATOM   7951 O O   . ALA E 5 196 ? 132.765 154.587 93.934  1.00 32.23 ? 184 ALA E O   1 
ATOM   7952 C CB  . ALA E 5 196 ? 132.386 157.321 96.006  1.00 22.32 ? 184 ALA E CB  1 
ATOM   7953 N N   . SER E 5 197 ? 131.161 154.581 95.496  1.00 35.87 ? 185 SER E N   1 
ATOM   7954 C CA  . SER E 5 197 ? 130.332 153.614 94.789  1.00 37.60 ? 185 SER E CA  1 
ATOM   7955 C C   . SER E 5 197 ? 129.515 154.323 93.717  1.00 46.04 ? 185 SER E C   1 
ATOM   7956 O O   . SER E 5 197 ? 128.899 155.361 93.980  1.00 46.79 ? 185 SER E O   1 
ATOM   7957 C CB  . SER E 5 197 ? 129.405 152.881 95.758  1.00 39.55 ? 185 SER E CB  1 
ATOM   7958 O OG  . SER E 5 197 ? 129.986 151.663 96.187  1.00 45.97 ? 185 SER E OG  1 
ATOM   7959 N N   . GLY E 5 198 ? 129.510 153.756 92.513  1.00 44.09 ? 186 GLY E N   1 
ATOM   7960 C CA  . GLY E 5 198 ? 128.803 154.348 91.396  1.00 40.58 ? 186 GLY E CA  1 
ATOM   7961 C C   . GLY E 5 198 ? 129.548 155.446 90.673  1.00 38.92 ? 186 GLY E C   1 
ATOM   7962 O O   . GLY E 5 198 ? 128.994 156.030 89.735  1.00 39.57 ? 186 GLY E O   1 
ATOM   7963 N N   . VAL E 5 199 ? 130.778 155.750 91.074  1.00 30.80 ? 187 VAL E N   1 
ATOM   7964 C CA  . VAL E 5 199 ? 131.592 156.765 90.411  1.00 31.58 ? 187 VAL E CA  1 
ATOM   7965 C C   . VAL E 5 199 ? 132.337 156.091 89.261  1.00 37.62 ? 187 VAL E C   1 
ATOM   7966 O O   . VAL E 5 199 ? 132.970 155.050 89.487  1.00 40.23 ? 187 VAL E O   1 
ATOM   7967 C CB  . VAL E 5 199 ? 132.562 157.429 91.400  1.00 31.88 ? 187 VAL E CB  1 
ATOM   7968 C CG1 . VAL E 5 199 ? 133.632 158.229 90.668  1.00 28.62 ? 187 VAL E CG1 1 
ATOM   7969 C CG2 . VAL E 5 199 ? 131.796 158.317 92.355  1.00 33.41 ? 187 VAL E CG2 1 
ATOM   7970 N N   . PRO E 5 200 ? 132.303 156.615 88.029  1.00 44.62 ? 188 PRO E N   1 
ATOM   7971 C CA  . PRO E 5 200 ? 133.042 155.953 86.947  1.00 43.35 ? 188 PRO E CA  1 
ATOM   7972 C C   . PRO E 5 200 ? 134.543 155.987 87.190  1.00 39.10 ? 188 PRO E C   1 
ATOM   7973 O O   . PRO E 5 200 ? 135.064 156.855 87.893  1.00 38.27 ? 188 PRO E O   1 
ATOM   7974 C CB  . PRO E 5 200 ? 132.655 156.758 85.702  1.00 41.96 ? 188 PRO E CB  1 
ATOM   7975 C CG  . PRO E 5 200 ? 132.219 158.069 86.214  1.00 41.61 ? 188 PRO E CG  1 
ATOM   7976 C CD  . PRO E 5 200 ? 131.572 157.793 87.528  1.00 42.46 ? 188 PRO E CD  1 
ATOM   7977 N N   . ASP E 5 201 ? 135.258 155.014 86.619  1.00 38.85 ? 189 ASP E N   1 
ATOM   7978 C CA  . ASP E 5 201 ? 136.715 154.883 86.912  1.00 41.18 ? 189 ASP E CA  1 
ATOM   7979 C C   . ASP E 5 201 ? 137.530 156.067 86.377  1.00 42.65 ? 189 ASP E C   1 
ATOM   7980 O O   . ASP E 5 201 ? 138.694 156.203 86.808  1.00 43.73 ? 189 ASP E O   1 
ATOM   7981 C CB  . ASP E 5 201 ? 137.253 153.557 86.399  1.00 43.63 ? 189 ASP E CB  1 
ATOM   7982 C CG  . ASP E 5 201 ? 136.600 152.324 87.007  1.00 46.99 ? 189 ASP E CG  1 
ATOM   7983 O OD1 . ASP E 5 201 ? 135.703 152.498 87.858  1.00 45.55 ? 189 ASP E OD1 1 
ATOM   7984 O OD2 . ASP E 5 201 ? 136.994 151.203 86.624  1.00 44.69 ? 189 ASP E OD2 1 
ATOM   7985 N N   . ARG E 5 202 ? 136.981 156.873 85.466  1.00 43.47 ? 190 ARG E N   1 
ATOM   7986 C CA  . ARG E 5 202 ? 137.790 157.951 84.907  1.00 47.83 ? 190 ARG E CA  1 
ATOM   7987 C C   . ARG E 5 202 ? 138.362 158.846 86.002  1.00 50.37 ? 190 ARG E C   1 
ATOM   7988 O O   . ARG E 5 202 ? 139.488 159.340 85.881  1.00 48.82 ? 190 ARG E O   1 
ATOM   7989 C CB  . ARG E 5 202 ? 136.967 158.766 83.908  1.00 46.80 ? 190 ARG E CB  1 
ATOM   7990 C CG  . ARG E 5 202 ? 135.663 159.351 84.433  1.00 47.36 ? 190 ARG E CG  1 
ATOM   7991 C CD  . ARG E 5 202 ? 135.157 160.446 83.503  1.00 45.61 ? 190 ARG E CD  1 
ATOM   7992 N NE  . ARG E 5 202 ? 133.770 160.816 83.759  1.00 46.25 ? 190 ARG E NE  1 
ATOM   7993 C CZ  . ARG E 5 202 ? 132.718 160.042 83.519  1.00 49.13 ? 190 ARG E CZ  1 
ATOM   7994 N NH1 . ARG E 5 202 ? 132.846 158.838 82.984  1.00 49.69 ? 190 ARG E NH1 1 
ATOM   7995 N NH2 . ARG E 5 202 ? 131.503 160.493 83.815  1.00 47.47 ? 190 ARG E NH2 1 
ATOM   7996 N N   . PHE E 5 203 ? 137.607 159.064 87.075  1.00 42.59 ? 191 PHE E N   1 
ATOM   7997 C CA  . PHE E 5 203 ? 138.119 159.837 88.197  1.00 35.74 ? 191 PHE E CA  1 
ATOM   7998 C C   . PHE E 5 203 ? 139.249 159.084 88.889  1.00 37.28 ? 191 PHE E C   1 
ATOM   7999 O O   . PHE E 5 203 ? 139.186 157.869 89.088  1.00 42.62 ? 191 PHE E O   1 
ATOM   8000 C CB  . PHE E 5 203 ? 137.006 160.133 89.200  1.00 35.11 ? 191 PHE E CB  1 
ATOM   8001 C CG  . PHE E 5 203 ? 135.902 160.984 88.648  1.00 32.12 ? 191 PHE E CG  1 
ATOM   8002 C CD1 . PHE E 5 203 ? 136.009 162.362 88.647  1.00 35.25 ? 191 PHE E CD1 1 
ATOM   8003 C CD2 . PHE E 5 203 ? 134.753 160.408 88.141  1.00 37.37 ? 191 PHE E CD2 1 
ATOM   8004 C CE1 . PHE E 5 203 ? 134.994 163.147 88.143  1.00 35.41 ? 191 PHE E CE1 1 
ATOM   8005 C CE2 . PHE E 5 203 ? 133.734 161.189 87.637  1.00 37.57 ? 191 PHE E CE2 1 
ATOM   8006 C CZ  . PHE E 5 203 ? 133.856 162.560 87.639  1.00 39.33 ? 191 PHE E CZ  1 
ATOM   8007 N N   . SER E 5 204 ? 140.313 159.828 89.211  1.00 32.34 ? 192 SER E N   1 
ATOM   8008 C CA  . SER E 5 204 ? 141.500 159.213 89.860  1.00 36.88 ? 192 SER E CA  1 
ATOM   8009 C C   . SER E 5 204 ? 142.204 160.247 90.748  1.00 36.51 ? 192 SER E C   1 
ATOM   8010 O O   . SER E 5 204 ? 142.403 161.389 90.280  1.00 41.29 ? 192 SER E O   1 
ATOM   8011 C CB  . SER E 5 204 ? 142.439 158.629 88.835  1.00 40.13 ? 192 SER E CB  1 
ATOM   8012 O OG  . SER E 5 204 ? 142.569 159.495 87.717  1.00 36.31 ? 192 SER E OG  1 
ATOM   8013 N N   . GLY E 5 205 ? 142.564 159.860 91.973  1.00 34.37 ? 193 GLY E N   1 
ATOM   8014 C CA  . GLY E 5 205 ? 143.221 160.744 92.919  1.00 31.05 ? 193 GLY E CA  1 
ATOM   8015 C C   . GLY E 5 205 ? 144.596 160.216 93.259  1.00 29.47 ? 193 GLY E C   1 
ATOM   8016 O O   . GLY E 5 205 ? 144.803 159.010 93.405  1.00 34.83 ? 193 GLY E O   1 
ATOM   8017 N N   . SER E 5 206 ? 145.542 161.139 93.379  1.00 28.22 ? 194 SER E N   1 
ATOM   8018 C CA  . SER E 5 206 ? 146.932 160.783 93.622  1.00 35.48 ? 194 SER E CA  1 
ATOM   8019 C C   . SER E 5 206 ? 147.650 162.010 94.167  1.00 40.83 ? 194 SER E C   1 
ATOM   8020 O O   . SER E 5 206 ? 147.101 163.114 94.192  1.00 46.19 ? 194 SER E O   1 
ATOM   8021 C CB  . SER E 5 206 ? 147.592 160.264 92.341  1.00 44.09 ? 194 SER E CB  1 
ATOM   8022 O OG  . SER E 5 206 ? 147.093 160.946 91.204  1.00 43.65 ? 194 SER E OG  1 
ATOM   8023 N N   . GLY E 5 207 ? 148.884 161.804 94.607  1.00 47.02 ? 195 GLY E N   1 
ATOM   8024 C CA  . GLY E 5 207 ? 149.731 162.861 95.106  1.00 47.78 ? 195 GLY E CA  1 
ATOM   8025 C C   . GLY E 5 207 ? 150.589 162.360 96.244  1.00 47.32 ? 195 GLY E C   1 
ATOM   8026 O O   . GLY E 5 207 ? 150.852 161.166 96.374  1.00 48.62 ? 195 GLY E O   1 
ATOM   8027 N N   . SER E 5 208 ? 151.022 163.300 97.079  1.00 44.11 ? 196 SER E N   1 
ATOM   8028 C CA  . SER E 5 208 ? 151.811 163.007 98.266  1.00 41.78 ? 196 SER E CA  1 
ATOM   8029 C C   . SER E 5 208 ? 151.269 163.864 99.402  1.00 40.83 ? 196 SER E C   1 
ATOM   8030 O O   . SER E 5 208 ? 150.223 164.507 99.273  1.00 50.66 ? 196 SER E O   1 
ATOM   8031 C CB  . SER E 5 208 ? 153.300 163.264 98.005  1.00 50.38 ? 196 SER E CB  1 
ATOM   8032 O OG  . SER E 5 208 ? 153.549 164.644 97.802  1.00 44.01 ? 196 SER E OG  1 
ATOM   8033 N N   . GLY E 5 209 ? 151.979 163.870 100.525 1.00 42.73 ? 197 GLY E N   1 
ATOM   8034 C CA  . GLY E 5 209 ? 151.603 164.717 101.639 1.00 43.93 ? 197 GLY E CA  1 
ATOM   8035 C C   . GLY E 5 209 ? 151.629 166.187 101.274 1.00 44.93 ? 197 GLY E C   1 
ATOM   8036 O O   . GLY E 5 209 ? 152.587 166.659 100.656 1.00 48.62 ? 197 GLY E O   1 
ATOM   8037 N N   . THR E 5 210 ? 150.570 166.913 101.635 1.00 40.81 ? 198 THR E N   1 
ATOM   8038 C CA  . THR E 5 210 ? 150.481 168.358 101.416 1.00 45.35 ? 198 THR E CA  1 
ATOM   8039 C C   . THR E 5 210 ? 150.414 168.708 99.926  1.00 42.92 ? 198 THR E C   1 
ATOM   8040 O O   . THR E 5 210 ? 150.694 169.839 99.525  1.00 45.41 ? 198 THR E O   1 
ATOM   8041 C CB  . THR E 5 210 ? 151.651 169.083 102.097 1.00 47.07 ? 198 THR E CB  1 
ATOM   8042 O OG1 . THR E 5 210 ? 151.842 168.542 103.409 1.00 45.99 ? 198 THR E OG1 1 
ATOM   8043 C CG2 . THR E 5 210 ? 151.389 170.586 102.236 1.00 45.88 ? 198 THR E CG2 1 
ATOM   8044 N N   . ALA E 5 211 ? 150.032 167.750 99.082  1.00 30.63 ? 199 ALA E N   1 
ATOM   8045 C CA  . ALA E 5 211 ? 149.866 168.021 97.656  1.00 30.67 ? 199 ALA E CA  1 
ATOM   8046 C C   . ALA E 5 211 ? 148.976 166.929 97.083  1.00 38.29 ? 199 ALA E C   1 
ATOM   8047 O O   . ALA E 5 211 ? 149.395 165.769 97.010  1.00 49.29 ? 199 ALA E O   1 
ATOM   8048 C CB  . ALA E 5 211 ? 151.211 168.069 96.946  1.00 42.16 ? 199 ALA E CB  1 
ATOM   8049 N N   . PHE E 5 212 ? 147.766 167.302 96.673  1.00 36.91 ? 200 PHE E N   1 
ATOM   8050 C CA  . PHE E 5 212 ? 146.740 166.358 96.257  1.00 37.03 ? 200 PHE E CA  1 
ATOM   8051 C C   . PHE E 5 212 ? 146.158 166.802 94.927  1.00 36.31 ? 200 PHE E C   1 
ATOM   8052 O O   . PHE E 5 212 ? 145.858 167.983 94.739  1.00 38.72 ? 200 PHE E O   1 
ATOM   8053 C CB  . PHE E 5 212 ? 145.635 166.257 97.312  1.00 34.62 ? 200 PHE E CB  1 
ATOM   8054 C CG  . PHE E 5 212 ? 146.152 166.221 98.720  1.00 34.39 ? 200 PHE E CG  1 
ATOM   8055 C CD1 . PHE E 5 212 ? 146.505 165.023 99.307  1.00 32.69 ? 200 PHE E CD1 1 
ATOM   8056 C CD2 . PHE E 5 212 ? 146.289 167.384 99.455  1.00 40.99 ? 200 PHE E CD2 1 
ATOM   8057 C CE1 . PHE E 5 212 ? 146.978 164.983 100.596 1.00 31.08 ? 200 PHE E CE1 1 
ATOM   8058 C CE2 . PHE E 5 212 ? 146.766 167.348 100.745 1.00 38.94 ? 200 PHE E CE2 1 
ATOM   8059 C CZ  . PHE E 5 212 ? 147.110 166.145 101.315 1.00 33.93 ? 200 PHE E CZ  1 
ATOM   8060 N N   . THR E 5 213 ? 146.003 165.847 94.012  1.00 29.43 ? 201 THR E N   1 
ATOM   8061 C CA  . THR E 5 213 ? 145.526 166.116 92.664  1.00 33.24 ? 201 THR E CA  1 
ATOM   8062 C C   . THR E 5 213 ? 144.392 165.162 92.326  1.00 35.04 ? 201 THR E C   1 
ATOM   8063 O O   . THR E 5 213 ? 144.449 163.975 92.659  1.00 41.50 ? 201 THR E O   1 
ATOM   8064 C CB  . THR E 5 213 ? 146.648 165.962 91.628  1.00 40.79 ? 201 THR E CB  1 
ATOM   8065 O OG1 . THR E 5 213 ? 146.827 164.575 91.313  1.00 39.26 ? 201 THR E OG1 1 
ATOM   8066 C CG2 . THR E 5 213 ? 147.957 166.530 92.158  1.00 36.87 ? 201 THR E CG2 1 
ATOM   8067 N N   . LEU E 5 214 ? 143.365 165.693 91.670  1.00 31.94 ? 202 LEU E N   1 
ATOM   8068 C CA  . LEU E 5 214 ? 142.278 164.907 91.104  1.00 26.70 ? 202 LEU E CA  1 
ATOM   8069 C C   . LEU E 5 214 ? 142.379 164.977 89.589  1.00 38.78 ? 202 LEU E C   1 
ATOM   8070 O O   . LEU E 5 214 ? 142.241 166.057 89.008  1.00 47.36 ? 202 LEU E O   1 
ATOM   8071 C CB  . LEU E 5 214 ? 140.918 165.432 91.571  1.00 33.09 ? 202 LEU E CB  1 
ATOM   8072 C CG  . LEU E 5 214 ? 139.660 164.715 91.067  1.00 38.50 ? 202 LEU E CG  1 
ATOM   8073 C CD1 . LEU E 5 214 ? 139.519 163.352 91.696  1.00 36.64 ? 202 LEU E CD1 1 
ATOM   8074 C CD2 . LEU E 5 214 ? 138.435 165.547 91.357  1.00 37.04 ? 202 LEU E CD2 1 
ATOM   8075 N N   . THR E 5 215 ? 142.603 163.828 88.957  1.00 43.89 ? 203 THR E N   1 
ATOM   8076 C CA  . THR E 5 215 ? 142.790 163.737 87.516  1.00 40.59 ? 203 THR E CA  1 
ATOM   8077 C C   . THR E 5 215 ? 141.576 163.074 86.883  1.00 42.45 ? 203 THR E C   1 
ATOM   8078 O O   . THR E 5 215 ? 141.095 162.045 87.366  1.00 42.11 ? 203 THR E O   1 
ATOM   8079 C CB  . THR E 5 215 ? 144.051 162.941 87.165  1.00 41.68 ? 203 THR E CB  1 
ATOM   8080 O OG1 . THR E 5 215 ? 143.787 161.539 87.291  1.00 44.16 ? 203 THR E OG1 1 
ATOM   8081 C CG2 . THR E 5 215 ? 145.199 163.323 88.086  1.00 41.33 ? 203 THR E CG2 1 
ATOM   8082 N N   . ILE E 5 216 ? 141.089 163.676 85.801  1.00 50.23 ? 204 ILE E N   1 
ATOM   8083 C CA  . ILE E 5 216 ? 139.954 163.173 85.037  1.00 53.68 ? 204 ILE E CA  1 
ATOM   8084 C C   . ILE E 5 216 ? 140.432 162.938 83.612  1.00 56.13 ? 204 ILE E C   1 
ATOM   8085 O O   . ILE E 5 216 ? 141.075 163.811 83.019  1.00 59.59 ? 204 ILE E O   1 
ATOM   8086 C CB  . ILE E 5 216 ? 138.761 164.150 85.057  1.00 53.95 ? 204 ILE E CB  1 
ATOM   8087 C CG1 . ILE E 5 216 ? 138.527 164.716 86.465  1.00 45.15 ? 204 ILE E CG1 1 
ATOM   8088 C CG2 . ILE E 5 216 ? 137.487 163.455 84.569  1.00 53.68 ? 204 ILE E CG2 1 
ATOM   8089 C CD1 . ILE E 5 216 ? 137.333 165.641 86.558  1.00 49.09 ? 204 ILE E CD1 1 
ATOM   8090 N N   . SER E 5 217 ? 140.125 161.760 83.074  1.00 57.90 ? 205 SER E N   1 
ATOM   8091 C CA  . SER E 5 217 ? 140.470 161.388 81.711  1.00 63.24 ? 205 SER E CA  1 
ATOM   8092 C C   . SER E 5 217 ? 139.200 161.059 80.940  1.00 63.65 ? 205 SER E C   1 
ATOM   8093 O O   . SER E 5 217 ? 138.238 160.524 81.498  1.00 67.33 ? 205 SER E O   1 
ATOM   8094 C CB  . SER E 5 217 ? 141.422 160.188 81.688  1.00 66.61 ? 205 SER E CB  1 
ATOM   8095 O OG  . SER E 5 217 ? 142.745 160.585 82.006  1.00 66.92 ? 205 SER E OG  1 
ATOM   8096 N N   . ARG E 5 218 ? 139.207 161.376 79.648  1.00 65.32 ? 206 ARG E N   1 
ATOM   8097 C CA  . ARG E 5 218 ? 138.032 161.205 78.798  1.00 64.35 ? 206 ARG E CA  1 
ATOM   8098 C C   . ARG E 5 218 ? 136.848 161.989 79.359  1.00 68.22 ? 206 ARG E C   1 
ATOM   8099 O O   . ARG E 5 218 ? 135.721 161.495 79.441  1.00 64.76 ? 206 ARG E O   1 
ATOM   8100 C CB  . ARG E 5 218 ? 137.684 159.724 78.641  1.00 60.91 ? 206 ARG E CB  1 
ATOM   8101 N N   . LEU E 5 219 ? 137.126 163.227 79.765  1.00 69.49 ? 207 LEU E N   1 
ATOM   8102 C CA  . LEU E 5 219 ? 136.090 164.099 80.301  1.00 65.02 ? 207 LEU E CA  1 
ATOM   8103 C C   . LEU E 5 219 ? 135.001 164.332 79.264  1.00 67.18 ? 207 LEU E C   1 
ATOM   8104 O O   . LEU E 5 219 ? 135.281 164.630 78.100  1.00 70.07 ? 207 LEU E O   1 
ATOM   8105 C CB  . LEU E 5 219 ? 136.706 165.432 80.733  1.00 62.88 ? 207 LEU E CB  1 
ATOM   8106 C CG  . LEU E 5 219 ? 135.772 166.566 81.164  1.00 61.81 ? 207 LEU E CG  1 
ATOM   8107 C CD1 . LEU E 5 219 ? 134.883 166.137 82.314  1.00 64.08 ? 207 LEU E CD1 1 
ATOM   8108 C CD2 . LEU E 5 219 ? 136.589 167.785 81.552  1.00 63.80 ? 207 LEU E CD2 1 
ATOM   8109 N N   . GLU E 5 220 ? 133.749 164.198 79.695  1.00 65.51 ? 208 GLU E N   1 
ATOM   8110 C CA  . GLU E 5 220 ? 132.596 164.365 78.820  1.00 70.30 ? 208 GLU E CA  1 
ATOM   8111 C C   . GLU E 5 220 ? 131.515 165.103 79.602  1.00 67.46 ? 208 GLU E C   1 
ATOM   8112 O O   . GLU E 5 220 ? 131.732 165.543 80.735  1.00 65.59 ? 208 GLU E O   1 
ATOM   8113 C CB  . GLU E 5 220 ? 132.129 163.006 78.273  1.00 67.72 ? 208 GLU E CB  1 
ATOM   8114 C CG  . GLU E 5 220 ? 131.746 161.963 79.333  1.00 67.06 ? 208 GLU E CG  1 
ATOM   8115 C CD  . GLU E 5 220 ? 130.298 162.050 79.787  1.00 69.98 ? 208 GLU E CD  1 
ATOM   8116 O OE1 . GLU E 5 220 ? 129.468 162.671 79.089  1.00 68.54 ? 208 GLU E OE1 1 
ATOM   8117 O OE2 . GLU E 5 220 ? 129.986 161.490 80.859  1.00 70.17 ? 208 GLU E OE2 1 
ATOM   8118 N N   . ALA E 5 221 ? 130.343 165.246 78.988  1.00 69.09 ? 209 ALA E N   1 
ATOM   8119 C CA  . ALA E 5 221 ? 129.278 166.058 79.555  1.00 70.44 ? 209 ALA E CA  1 
ATOM   8120 C C   . ALA E 5 221 ? 128.763 165.435 80.852  1.00 70.45 ? 209 ALA E C   1 
ATOM   8121 O O   . ALA E 5 221 ? 129.133 164.322 81.236  1.00 68.60 ? 209 ALA E O   1 
ATOM   8122 C CB  . ALA E 5 221 ? 128.149 166.225 78.541  1.00 69.73 ? 209 ALA E CB  1 
ATOM   8123 N N   . GLU E 5 222 ? 127.900 166.181 81.543  1.00 61.46 ? 210 GLU E N   1 
ATOM   8124 C CA  . GLU E 5 222 ? 127.341 165.744 82.818  1.00 57.92 ? 210 GLU E CA  1 
ATOM   8125 C C   . GLU E 5 222 ? 128.443 165.514 83.847  1.00 56.72 ? 210 GLU E C   1 
ATOM   8126 O O   . GLU E 5 222 ? 128.307 164.658 84.727  1.00 51.79 ? 210 GLU E O   1 
ATOM   8127 C CB  . GLU E 5 222 ? 126.515 164.469 82.630  1.00 54.53 ? 210 GLU E CB  1 
ATOM   8128 N N   . ASP E 5 223 ? 129.539 166.268 83.739  1.00 56.18 ? 211 ASP E N   1 
ATOM   8129 C CA  . ASP E 5 223 ? 130.650 166.201 84.679  1.00 53.42 ? 211 ASP E CA  1 
ATOM   8130 C C   . ASP E 5 223 ? 131.127 167.611 85.043  1.00 50.11 ? 211 ASP E C   1 
ATOM   8131 O O   . ASP E 5 223 ? 132.236 167.786 85.554  1.00 51.01 ? 211 ASP E O   1 
ATOM   8132 C CB  . ASP E 5 223 ? 131.778 165.364 84.061  1.00 51.17 ? 211 ASP E CB  1 
ATOM   8133 C CG  . ASP E 5 223 ? 132.846 164.929 85.066  1.00 54.08 ? 211 ASP E CG  1 
ATOM   8134 O OD1 . ASP E 5 223 ? 132.886 165.419 86.210  1.00 52.98 ? 211 ASP E OD1 1 
ATOM   8135 O OD2 . ASP E 5 223 ? 133.677 164.077 84.684  1.00 55.15 ? 211 ASP E OD2 1 
ATOM   8136 N N   . VAL E 5 224 ? 130.311 168.631 84.767  1.00 51.43 ? 212 VAL E N   1 
ATOM   8137 C CA  . VAL E 5 224 ? 130.675 170.023 85.000  1.00 51.82 ? 212 VAL E CA  1 
ATOM   8138 C C   . VAL E 5 224 ? 130.062 170.467 86.319  1.00 51.25 ? 212 VAL E C   1 
ATOM   8139 O O   . VAL E 5 224 ? 128.838 170.432 86.490  1.00 55.88 ? 212 VAL E O   1 
ATOM   8140 C CB  . VAL E 5 224 ? 130.200 170.916 83.842  1.00 53.37 ? 212 VAL E CB  1 
ATOM   8141 C CG1 . VAL E 5 224 ? 130.872 172.275 83.911  1.00 52.77 ? 212 VAL E CG1 1 
ATOM   8142 C CG2 . VAL E 5 224 ? 130.480 170.245 82.501  1.00 53.08 ? 212 VAL E CG2 1 
ATOM   8143 N N   . GLY E 5 225 ? 130.906 170.890 87.247  1.00 43.10 ? 213 GLY E N   1 
ATOM   8144 C CA  . GLY E 5 225 ? 130.421 171.309 88.541  1.00 41.27 ? 213 GLY E CA  1 
ATOM   8145 C C   . GLY E 5 225 ? 131.519 171.930 89.369  1.00 41.72 ? 213 GLY E C   1 
ATOM   8146 O O   . GLY E 5 225 ? 132.557 172.338 88.848  1.00 49.57 ? 213 GLY E O   1 
ATOM   8147 N N   . VAL E 5 226 ? 131.271 171.991 90.675  1.00 28.82 ? 214 VAL E N   1 
ATOM   8148 C CA  . VAL E 5 226 ? 132.187 172.587 91.640  1.00 29.20 ? 214 VAL E CA  1 
ATOM   8149 C C   . VAL E 5 226 ? 132.802 171.463 92.460  1.00 31.76 ? 214 VAL E C   1 
ATOM   8150 O O   . VAL E 5 226 ? 132.079 170.653 93.051  1.00 33.37 ? 214 VAL E O   1 
ATOM   8151 C CB  . VAL E 5 226 ? 131.469 173.600 92.549  1.00 37.66 ? 214 VAL E CB  1 
ATOM   8152 C CG1 . VAL E 5 226 ? 132.473 174.346 93.419  1.00 37.07 ? 214 VAL E CG1 1 
ATOM   8153 C CG2 . VAL E 5 226 ? 130.639 174.569 91.713  1.00 32.78 ? 214 VAL E CG2 1 
ATOM   8154 N N   . TYR E 5 227 ? 134.131 171.421 92.502  1.00 31.82 ? 215 TYR E N   1 
ATOM   8155 C CA  . TYR E 5 227 ? 134.877 170.362 93.165  1.00 32.17 ? 215 TYR E CA  1 
ATOM   8156 C C   . TYR E 5 227 ? 135.421 170.876 94.490  1.00 36.18 ? 215 TYR E C   1 
ATOM   8157 O O   . TYR E 5 227 ? 136.181 171.848 94.517  1.00 39.97 ? 215 TYR E O   1 
ATOM   8158 C CB  . TYR E 5 227 ? 136.051 169.886 92.304  1.00 37.44 ? 215 TYR E CB  1 
ATOM   8159 C CG  . TYR E 5 227 ? 135.693 169.149 91.029  1.00 32.95 ? 215 TYR E CG  1 
ATOM   8160 C CD1 . TYR E 5 227 ? 135.003 169.779 90.002  1.00 38.66 ? 215 TYR E CD1 1 
ATOM   8161 C CD2 . TYR E 5 227 ? 136.077 167.832 90.841  1.00 32.62 ? 215 TYR E CD2 1 
ATOM   8162 C CE1 . TYR E 5 227 ? 134.692 169.111 88.835  1.00 43.06 ? 215 TYR E CE1 1 
ATOM   8163 C CE2 . TYR E 5 227 ? 135.773 167.157 89.678  1.00 37.17 ? 215 TYR E CE2 1 
ATOM   8164 C CZ  . TYR E 5 227 ? 135.090 167.804 88.673  1.00 44.61 ? 215 TYR E CZ  1 
ATOM   8165 O OH  . TYR E 5 227 ? 134.774 167.133 87.515  1.00 49.03 ? 215 TYR E OH  1 
ATOM   8166 N N   . TYR E 5 228 ? 135.056 170.205 95.584  1.00 29.06 ? 216 TYR E N   1 
ATOM   8167 C CA  . TYR E 5 228 ? 135.475 170.589 96.925  1.00 23.41 ? 216 TYR E CA  1 
ATOM   8168 C C   . TYR E 5 228 ? 136.399 169.529 97.503  1.00 20.89 ? 216 TYR E C   1 
ATOM   8169 O O   . TYR E 5 228 ? 136.193 168.330 97.303  1.00 27.63 ? 216 TYR E O   1 
ATOM   8170 C CB  . TYR E 5 228 ? 134.278 170.782 97.862  1.00 19.82 ? 216 TYR E CB  1 
ATOM   8171 C CG  . TYR E 5 228 ? 133.370 171.923 97.476  1.00 22.15 ? 216 TYR E CG  1 
ATOM   8172 C CD1 . TYR E 5 228 ? 133.666 173.224 97.846  1.00 21.98 ? 216 TYR E CD1 1 
ATOM   8173 C CD2 . TYR E 5 228 ? 132.211 171.697 96.750  1.00 27.92 ? 216 TYR E CD2 1 
ATOM   8174 C CE1 . TYR E 5 228 ? 132.838 174.270 97.498  1.00 24.96 ? 216 TYR E CE1 1 
ATOM   8175 C CE2 . TYR E 5 228 ? 131.376 172.737 96.398  1.00 25.70 ? 216 TYR E CE2 1 
ATOM   8176 C CZ  . TYR E 5 228 ? 131.694 174.021 96.774  1.00 26.40 ? 216 TYR E CZ  1 
ATOM   8177 O OH  . TYR E 5 228 ? 130.865 175.060 96.424  1.00 23.19 ? 216 TYR E OH  1 
ATOM   8178 N N   . CYS E 5 229 ? 137.423 169.989 98.220  1.00 19.58 ? 217 CYS E N   1 
ATOM   8179 C CA  . CYS E 5 229 ? 138.377 169.127 98.905  1.00 20.56 ? 217 CYS E CA  1 
ATOM   8180 C C   . CYS E 5 229 ? 138.256 169.348 100.404 1.00 22.48 ? 217 CYS E C   1 
ATOM   8181 O O   . CYS E 5 229 ? 138.225 170.493 100.864 1.00 35.59 ? 217 CYS E O   1 
ATOM   8182 C CB  . CYS E 5 229 ? 139.810 169.397 98.439  1.00 28.55 ? 217 CYS E CB  1 
ATOM   8183 S SG  . CYS E 5 229 ? 140.323 171.127 98.476  1.00 39.55 ? 217 CYS E SG  1 
ATOM   8184 N N   . MET E 5 230 ? 138.190 168.251 101.156 1.00 23.15 ? 218 MET E N   1 
ATOM   8185 C CA  . MET E 5 230 ? 137.979 168.273 102.595 1.00 23.23 ? 218 MET E CA  1 
ATOM   8186 C C   . MET E 5 230 ? 139.035 167.411 103.266 1.00 21.27 ? 218 MET E C   1 
ATOM   8187 O O   . MET E 5 230 ? 139.570 166.480 102.661 1.00 40.90 ? 218 MET E O   1 
ATOM   8188 C CB  . MET E 5 230 ? 136.573 167.755 102.947 1.00 23.51 ? 218 MET E CB  1 
ATOM   8189 C CG  . MET E 5 230 ? 136.181 167.855 104.419 1.00 26.38 ? 218 MET E CG  1 
ATOM   8190 S SD  . MET E 5 230 ? 134.609 167.065 104.771 1.00 10.47 ? 218 MET E SD  1 
ATOM   8191 C CE  . MET E 5 230 ? 135.109 165.351 104.745 1.00 22.63 ? 218 MET E CE  1 
ATOM   8192 N N   . GLN E 5 231 ? 139.338 167.737 104.519 1.00 5.62  ? 219 GLN E N   1 
ATOM   8193 C CA  . GLN E 5 231 ? 140.199 166.929 105.368 1.00 19.57 ? 219 GLN E CA  1 
ATOM   8194 C C   . GLN E 5 231 ? 139.378 166.302 106.482 1.00 25.48 ? 219 GLN E C   1 
ATOM   8195 O O   . GLN E 5 231 ? 138.361 166.854 106.911 1.00 42.13 ? 219 GLN E O   1 
ATOM   8196 C CB  . GLN E 5 231 ? 141.329 167.761 105.976 1.00 30.22 ? 219 GLN E CB  1 
ATOM   8197 C CG  . GLN E 5 231 ? 140.895 168.884 106.925 1.00 25.87 ? 219 GLN E CG  1 
ATOM   8198 C CD  . GLN E 5 231 ? 140.864 168.474 108.388 1.00 22.50 ? 219 GLN E CD  1 
ATOM   8199 O OE1 . GLN E 5 231 ? 141.531 167.528 108.802 1.00 27.93 ? 219 GLN E OE1 1 
ATOM   8200 N NE2 . GLN E 5 231 ? 140.093 169.203 109.182 1.00 29.76 ? 219 GLN E NE2 1 
ATOM   8201 N N   . HIS E 5 232 ? 139.832 165.135 106.944 1.00 15.47 ? 220 HIS E N   1 
ATOM   8202 C CA  . HIS E 5 232 ? 139.214 164.455 108.074 1.00 16.43 ? 220 HIS E CA  1 
ATOM   8203 C C   . HIS E 5 232 ? 140.256 164.035 109.100 1.00 21.68 ? 220 HIS E C   1 
ATOM   8204 O O   . HIS E 5 232 ? 140.012 163.125 109.901 1.00 28.33 ? 220 HIS E O   1 
ATOM   8205 C CB  . HIS E 5 232 ? 138.419 163.240 107.609 1.00 22.16 ? 220 HIS E CB  1 
ATOM   8206 C CG  . HIS E 5 232 ? 137.172 163.002 108.398 1.00 15.85 ? 220 HIS E CG  1 
ATOM   8207 N ND1 . HIS E 5 232 ? 137.184 162.752 109.752 1.00 18.11 ? 220 HIS E ND1 1 
ATOM   8208 C CD2 . HIS E 5 232 ? 135.873 162.975 108.022 1.00 17.81 ? 220 HIS E CD2 1 
ATOM   8209 C CE1 . HIS E 5 232 ? 135.945 162.583 110.177 1.00 24.29 ? 220 HIS E CE1 1 
ATOM   8210 N NE2 . HIS E 5 232 ? 135.131 162.714 109.146 1.00 23.87 ? 220 HIS E NE2 1 
ATOM   8211 N N   . LEU E 5 233 ? 141.419 164.688 109.097 1.00 31.79 ? 221 LEU E N   1 
ATOM   8212 C CA  . LEU E 5 233 ? 142.458 164.361 110.063 1.00 33.91 ? 221 LEU E CA  1 
ATOM   8213 C C   . LEU E 5 233 ? 142.022 164.698 111.482 1.00 25.73 ? 221 LEU E C   1 
ATOM   8214 O O   . LEU E 5 233 ? 142.268 163.922 112.411 1.00 31.84 ? 221 LEU E O   1 
ATOM   8215 C CB  . LEU E 5 233 ? 143.746 165.106 109.708 1.00 32.42 ? 221 LEU E CB  1 
ATOM   8216 C CG  . LEU E 5 233 ? 144.969 164.895 110.603 1.00 32.08 ? 221 LEU E CG  1 
ATOM   8217 C CD1 . LEU E 5 233 ? 145.291 163.423 110.775 1.00 34.12 ? 221 LEU E CD1 1 
ATOM   8218 C CD2 . LEU E 5 233 ? 146.162 165.638 110.032 1.00 33.52 ? 221 LEU E CD2 1 
ATOM   8219 N N   . GLU E 5 234 ? 141.373 165.844 111.667 1.00 22.39 ? 222 GLU E N   1 
ATOM   8220 C CA  . GLU E 5 234 ? 140.930 166.265 112.987 1.00 26.61 ? 222 GLU E CA  1 
ATOM   8221 C C   . GLU E 5 234 ? 139.857 167.327 112.814 1.00 27.39 ? 222 GLU E C   1 
ATOM   8222 O O   . GLU E 5 234 ? 139.766 167.978 111.770 1.00 25.40 ? 222 GLU E O   1 
ATOM   8223 C CB  . GLU E 5 234 ? 142.086 166.810 113.841 1.00 30.61 ? 222 GLU E CB  1 
ATOM   8224 C CG  . GLU E 5 234 ? 143.064 167.753 113.123 1.00 30.68 ? 222 GLU E CG  1 
ATOM   8225 C CD  . GLU E 5 234 ? 144.369 167.924 113.872 1.00 29.99 ? 222 GLU E CD  1 
ATOM   8226 O OE1 . GLU E 5 234 ? 144.465 167.456 115.026 1.00 28.98 ? 222 GLU E OE1 1 
ATOM   8227 O OE2 . GLU E 5 234 ? 145.303 168.527 113.304 1.00 27.26 ? 222 GLU E OE2 1 
ATOM   8228 N N   . TYR E 5 235 ? 139.049 167.495 113.856 1.00 21.09 ? 223 TYR E N   1 
ATOM   8229 C CA  . TYR E 5 235 ? 138.009 168.510 113.808 1.00 22.40 ? 223 TYR E CA  1 
ATOM   8230 C C   . TYR E 5 235 ? 138.604 169.881 114.136 1.00 22.15 ? 223 TYR E C   1 
ATOM   8231 O O   . TYR E 5 235 ? 139.581 169.965 114.883 1.00 29.90 ? 223 TYR E O   1 
ATOM   8232 C CB  . TYR E 5 235 ? 136.890 168.179 114.791 1.00 33.36 ? 223 TYR E CB  1 
ATOM   8233 C CG  . TYR E 5 235 ? 136.171 166.889 114.467 1.00 37.27 ? 223 TYR E CG  1 
ATOM   8234 C CD1 . TYR E 5 235 ? 135.132 166.861 113.547 1.00 33.83 ? 223 TYR E CD1 1 
ATOM   8235 C CD2 . TYR E 5 235 ? 136.540 165.699 115.070 1.00 31.84 ? 223 TYR E CD2 1 
ATOM   8236 C CE1 . TYR E 5 235 ? 134.481 165.684 113.245 1.00 21.93 ? 223 TYR E CE1 1 
ATOM   8237 C CE2 . TYR E 5 235 ? 135.891 164.522 114.777 1.00 29.17 ? 223 TYR E CE2 1 
ATOM   8238 C CZ  . TYR E 5 235 ? 134.867 164.519 113.861 1.00 23.41 ? 223 TYR E CZ  1 
ATOM   8239 O OH  . TYR E 5 235 ? 134.225 163.342 113.567 1.00 31.12 ? 223 TYR E OH  1 
ATOM   8240 N N   . PRO E 5 236 ? 138.039 170.979 113.604 1.00 25.51 ? 224 PRO E N   1 
ATOM   8241 C CA  . PRO E 5 236 ? 136.885 171.076 112.699 1.00 20.68 ? 224 PRO E CA  1 
ATOM   8242 C C   . PRO E 5 236 ? 137.243 170.696 111.271 1.00 23.76 ? 224 PRO E C   1 
ATOM   8243 O O   . PRO E 5 236 ? 138.383 170.856 110.846 1.00 30.38 ? 224 PRO E O   1 
ATOM   8244 C CB  . PRO E 5 236 ? 136.480 172.549 112.820 1.00 20.16 ? 224 PRO E CB  1 
ATOM   8245 C CG  . PRO E 5 236 ? 137.762 173.259 113.089 1.00 22.71 ? 224 PRO E CG  1 
ATOM   8246 C CD  . PRO E 5 236 ? 138.582 172.310 113.928 1.00 32.63 ? 224 PRO E CD  1 
ATOM   8247 N N   . LEU E 5 237 ? 136.280 170.188 110.509 1.00 26.09 ? 225 LEU E N   1 
ATOM   8248 C CA  . LEU E 5 237 ? 136.499 169.774 109.131 1.00 25.19 ? 225 LEU E CA  1 
ATOM   8249 C C   . LEU E 5 237 ? 136.431 171.010 108.244 1.00 20.13 ? 225 LEU E C   1 
ATOM   8250 O O   . LEU E 5 237 ? 135.420 171.718 108.240 1.00 23.79 ? 225 LEU E O   1 
ATOM   8251 C CB  . LEU E 5 237 ? 135.459 168.742 108.698 1.00 17.80 ? 225 LEU E CB  1 
ATOM   8252 C CG  . LEU E 5 237 ? 135.242 167.552 109.635 1.00 16.44 ? 225 LEU E CG  1 
ATOM   8253 C CD1 . LEU E 5 237 ? 134.116 166.679 109.119 1.00 19.89 ? 225 LEU E CD1 1 
ATOM   8254 C CD2 . LEU E 5 237 ? 136.512 166.747 109.796 1.00 18.69 ? 225 LEU E CD2 1 
ATOM   8255 N N   . THR E 5 238 ? 137.503 171.263 107.501 1.00 8.41  ? 226 THR E N   1 
ATOM   8256 C CA  . THR E 5 238 ? 137.635 172.449 106.667 1.00 18.07 ? 226 THR E CA  1 
ATOM   8257 C C   . THR E 5 238 ? 137.596 172.045 105.203 1.00 16.08 ? 226 THR E C   1 
ATOM   8258 O O   . THR E 5 238 ? 138.359 171.174 104.775 1.00 19.95 ? 226 THR E O   1 
ATOM   8259 C CB  . THR E 5 238 ? 138.941 173.184 106.969 1.00 29.50 ? 226 THR E CB  1 
ATOM   8260 O OG1 . THR E 5 238 ? 140.048 172.310 106.723 1.00 33.41 ? 226 THR E OG1 1 
ATOM   8261 C CG2 . THR E 5 238 ? 138.973 173.644 108.417 1.00 29.23 ? 226 THR E CG2 1 
ATOM   8262 N N   . PHE E 5 239 ? 136.713 172.681 104.442 1.00 16.46 ? 227 PHE E N   1 
ATOM   8263 C CA  . PHE E 5 239 ? 136.591 172.429 103.015 1.00 15.78 ? 227 PHE E CA  1 
ATOM   8264 C C   . PHE E 5 239 ? 137.539 173.357 102.258 1.00 18.65 ? 227 PHE E C   1 
ATOM   8265 O O   . PHE E 5 239 ? 138.175 174.239 102.838 1.00 23.96 ? 227 PHE E O   1 
ATOM   8266 C CB  . PHE E 5 239 ? 135.146 172.625 102.563 1.00 23.04 ? 227 PHE E CB  1 
ATOM   8267 C CG  . PHE E 5 239 ? 134.214 171.534 103.001 1.00 15.33 ? 227 PHE E CG  1 
ATOM   8268 C CD1 . PHE E 5 239 ? 133.856 171.397 104.329 1.00 17.71 ? 227 PHE E CD1 1 
ATOM   8269 C CD2 . PHE E 5 239 ? 133.686 170.651 102.080 1.00 18.00 ? 227 PHE E CD2 1 
ATOM   8270 C CE1 . PHE E 5 239 ? 132.999 170.400 104.728 1.00 18.85 ? 227 PHE E CE1 1 
ATOM   8271 C CE2 . PHE E 5 239 ? 132.829 169.652 102.476 1.00 23.98 ? 227 PHE E CE2 1 
ATOM   8272 C CZ  . PHE E 5 239 ? 132.483 169.529 103.801 1.00 23.92 ? 227 PHE E CZ  1 
ATOM   8273 N N   . GLY E 5 240 ? 137.644 173.159 100.944 1.00 21.22 ? 228 GLY E N   1 
ATOM   8274 C CA  . GLY E 5 240 ? 138.367 174.063 100.082 1.00 21.25 ? 228 GLY E CA  1 
ATOM   8275 C C   . GLY E 5 240 ? 137.465 175.163 99.545  1.00 24.48 ? 228 GLY E C   1 
ATOM   8276 O O   . GLY E 5 240 ? 136.258 175.193 99.769  1.00 29.14 ? 228 GLY E O   1 
ATOM   8277 N N   . ALA E 5 241 ? 138.087 176.086 98.815  1.00 36.41 ? 229 ALA E N   1 
ATOM   8278 C CA  . ALA E 5 241 ? 137.336 177.187 98.225  1.00 33.63 ? 229 ALA E CA  1 
ATOM   8279 C C   . ALA E 5 241 ? 136.415 176.716 97.108  1.00 38.24 ? 229 ALA E C   1 
ATOM   8280 O O   . ALA E 5 241 ? 135.356 177.317 96.895  1.00 38.25 ? 229 ALA E O   1 
ATOM   8281 C CB  . ALA E 5 241 ? 138.296 178.251 97.693  1.00 39.47 ? 229 ALA E CB  1 
ATOM   8282 N N   . GLY E 5 242 ? 136.796 175.661 96.396  1.00 40.31 ? 230 GLY E N   1 
ATOM   8283 C CA  . GLY E 5 242 ? 136.045 175.158 95.265  1.00 38.28 ? 230 GLY E CA  1 
ATOM   8284 C C   . GLY E 5 242 ? 136.634 175.616 93.943  1.00 42.55 ? 230 GLY E C   1 
ATOM   8285 O O   . GLY E 5 242 ? 137.288 176.656 93.836  1.00 54.65 ? 230 GLY E O   1 
ATOM   8286 N N   . THR E 5 243 ? 136.398 174.800 92.915  1.00 37.65 ? 231 THR E N   1 
ATOM   8287 C CA  . THR E 5 243 ? 136.874 175.085 91.566  1.00 42.74 ? 231 THR E CA  1 
ATOM   8288 C C   . THR E 5 243 ? 135.735 174.854 90.587  1.00 47.74 ? 231 THR E C   1 
ATOM   8289 O O   . THR E 5 243 ? 135.234 173.733 90.471  1.00 50.68 ? 231 THR E O   1 
ATOM   8290 C CB  . THR E 5 243 ? 138.070 174.204 91.184  1.00 42.39 ? 231 THR E CB  1 
ATOM   8291 O OG1 . THR E 5 243 ? 137.599 172.971 90.628  1.00 46.59 ? 231 THR E OG1 1 
ATOM   8292 C CG2 . THR E 5 243 ? 138.951 173.909 92.391  1.00 46.12 ? 231 THR E CG2 1 
ATOM   8293 N N   . LYS E 5 244 ? 135.345 175.908 89.879  1.00 52.89 ? 232 LYS E N   1 
ATOM   8294 C CA  . LYS E 5 244 ? 134.291 175.840 88.879  1.00 49.68 ? 232 LYS E CA  1 
ATOM   8295 C C   . LYS E 5 244 ? 134.873 175.419 87.538  1.00 50.55 ? 232 LYS E C   1 
ATOM   8296 O O   . LYS E 5 244 ? 135.979 175.829 87.175  1.00 57.39 ? 232 LYS E O   1 
ATOM   8297 C CB  . LYS E 5 244 ? 133.591 177.193 88.736  1.00 49.71 ? 232 LYS E CB  1 
ATOM   8298 C CG  . LYS E 5 244 ? 132.155 177.105 88.255  1.00 49.53 ? 232 LYS E CG  1 
ATOM   8299 C CD  . LYS E 5 244 ? 131.603 178.483 87.933  1.00 50.49 ? 232 LYS E CD  1 
ATOM   8300 C CE  . LYS E 5 244 ? 130.134 178.423 87.548  1.00 50.90 ? 232 LYS E CE  1 
ATOM   8301 N NZ  . LYS E 5 244 ? 129.246 178.314 88.736  1.00 52.55 ? 232 LYS E NZ  1 
ATOM   8302 N N   . LEU E 5 245 ? 134.124 174.595 86.810  1.00 49.59 ? 233 LEU E N   1 
ATOM   8303 C CA  . LEU E 5 245 ? 134.476 174.177 85.459  1.00 56.56 ? 233 LEU E CA  1 
ATOM   8304 C C   . LEU E 5 245 ? 133.485 174.791 84.482  1.00 56.75 ? 233 LEU E C   1 
ATOM   8305 O O   . LEU E 5 245 ? 132.274 174.773 84.728  1.00 58.65 ? 233 LEU E O   1 
ATOM   8306 C CB  . LEU E 5 245 ? 134.468 172.652 85.331  1.00 52.08 ? 233 LEU E CB  1 
ATOM   8307 C CG  . LEU E 5 245 ? 135.383 171.843 86.257  1.00 51.22 ? 233 LEU E CG  1 
ATOM   8308 C CD1 . LEU E 5 245 ? 135.441 170.400 85.786  1.00 47.86 ? 233 LEU E CD1 1 
ATOM   8309 C CD2 . LEU E 5 245 ? 136.786 172.427 86.347  1.00 52.75 ? 233 LEU E CD2 1 
ATOM   8310 N N   . GLU E 5 246 ? 134.002 175.343 83.386  1.00 65.70 ? 234 GLU E N   1 
ATOM   8311 C CA  . GLU E 5 246 ? 133.187 175.982 82.364  1.00 68.99 ? 234 GLU E CA  1 
ATOM   8312 C C   . GLU E 5 246 ? 133.717 175.616 80.986  1.00 73.07 ? 234 GLU E C   1 
ATOM   8313 O O   . GLU E 5 246 ? 134.905 175.332 80.814  1.00 73.35 ? 234 GLU E O   1 
ATOM   8314 C CB  . GLU E 5 246 ? 133.175 177.507 82.530  1.00 66.37 ? 234 GLU E CB  1 
ATOM   8315 N N   . LEU E 5 247 ? 132.821 175.630 80.004  1.00 73.35 ? 235 LEU E N   1 
ATOM   8316 C CA  . LEU E 5 247 ? 133.176 175.288 78.633  1.00 73.66 ? 235 LEU E CA  1 
ATOM   8317 C C   . LEU E 5 247 ? 133.767 176.497 77.916  1.00 70.46 ? 235 LEU E C   1 
ATOM   8318 O O   . LEU E 5 247 ? 134.491 176.354 76.930  1.00 68.85 ? 235 LEU E O   1 
ATOM   8319 C CB  . LEU E 5 247 ? 131.948 174.777 77.875  1.00 73.87 ? 235 LEU E CB  1 
ATOM   8320 C CG  . LEU E 5 247 ? 131.163 173.602 78.475  1.00 70.27 ? 235 LEU E CG  1 
ATOM   8321 C CD1 . LEU E 5 247 ? 130.321 172.933 77.397  1.00 68.77 ? 235 LEU E CD1 1 
ATOM   8322 C CD2 . LEU E 5 247 ? 132.067 172.579 79.153  1.00 69.08 ? 235 LEU E CD2 1 
HETATM 8323 O OH  . SRO F 6 .   ? 136.723 149.103 169.208 1.00 24.78 ? 501 SRO A OH  1 
HETATM 8324 C CZ3 . SRO F 6 .   ? 136.582 148.452 167.981 1.00 24.84 ? 501 SRO A CZ3 1 
HETATM 8325 C CH2 . SRO F 6 .   ? 135.509 148.763 167.150 1.00 29.19 ? 501 SRO A CH2 1 
HETATM 8326 C CZ2 . SRO F 6 .   ? 135.366 148.115 165.931 1.00 28.66 ? 501 SRO A CZ2 1 
HETATM 8327 C CE2 . SRO F 6 .   ? 136.318 147.138 165.536 1.00 27.16 ? 501 SRO A CE2 1 
HETATM 8328 N NE1 . SRO F 6 .   ? 136.397 146.374 164.406 1.00 22.09 ? 501 SRO A NE1 1 
HETATM 8329 C CD1 . SRO F 6 .   ? 137.465 145.589 164.469 1.00 27.13 ? 501 SRO A CD1 1 
HETATM 8330 C CG  . SRO F 6 .   ? 138.112 145.843 165.663 1.00 26.68 ? 501 SRO A CG  1 
HETATM 8331 C CD2 . SRO F 6 .   ? 137.372 146.831 166.351 1.00 29.51 ? 501 SRO A CD2 1 
HETATM 8332 C CE3 . SRO F 6 .   ? 137.513 147.495 167.595 1.00 26.75 ? 501 SRO A CE3 1 
HETATM 8333 C CB  . SRO F 6 .   ? 139.382 145.145 166.143 1.00 24.11 ? 501 SRO A CB  1 
HETATM 8334 C CA  . SRO F 6 .   ? 140.574 146.071 166.366 1.00 28.99 ? 501 SRO A CA  1 
HETATM 8335 N NZ  . SRO F 6 .   ? 141.724 145.285 166.770 1.00 29.96 ? 501 SRO A NZ  1 
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