2026-05-13 OBS RCSB INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY INITIAL_RELEASE REPOSITORY OBSOLETE REPOSITORY EXPERIMENTAL_SUMMARY citation citation_author em_admin em_supersede _em_admin.current_status _em_admin.last_update RCSB RCSB 2023-06-13 2023-06-21 2023-06-21 2026-05-13 2026-05-13 2026-05-13 EMD-76932 National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS) GM111730 United States Michael J. Fox Foundation ASAP-000350 United States Local refinement map (1/2) of the human PI3KC3-C1 complex (EMD-40669) Chen M Hurley JH Autophagy, Lipid kinase, Complex, IMMUNE SYSTEM Chen M Nguyen TN Ren X Khuu G Cook ASI Zhao Y Yildiz A Lazarou M Hurley JH Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex. Nat.Struct.Mol.Biol. US 2025 40442316 doi:10.1038/s41594-025-01557-x 1545-9985 Chen M Ren X Cook A Hurley JH Structure and activation of the human autophagy-initiating ULK1C:PI3KC3-C1 supercomplex bioRxiv US 2023 doi:10.1101/2023.06.01.543278 2692-8205 EMD-40669 other EM volume
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 EMDB EMD-40669 other EM volume
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 EMDB EMD-41056 associated EM volume Human autophagy initiation PI3KC3-C1 complex Human autophagy initiation PI3KC3-C1 complex 0 1 2 3 4 Homo sapiens 0.362 singleParticle particle 0.25 7.4 25.0 C8H18N2O4S HEPES 300.0 NaCl sodium chloride 1.0 MgCl2 magnesium chloride 25.0 C9H15O6P TCEP Quantifoil R1.2/1.3 COPPER 300 CARBON HOLEY
25 mA
 ETHANE 100 277 FEI VITROBOT MARK IV FEI TALOS ARCTICA FLOOD BEAM BRIGHT FIELD FIELD EMISSION GUN 200 50.0 2.7 0.8 2.0 36000.0 NITROGEN GATAN K3 (6k x 4k) 1 2243 50.0 1 1229932 cryoSPARC 3.3.1 PHASE FLIPPING AND AMPLITUDE CORRECTION 3.28 FSC 0.143 CUT-OFF cryoSPARC 3.3.1 226147 MAXIMUM LIKELIHOOD cryoSPARC 3.3.1 MAXIMUM LIKELIHOOD cryoSPARC 3.3.1 4 266147.0 cryoSPARC 3.3.1 emd_41056.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 401.4 401.4 401.4 90.0 90.0 90.0 X Y Z -1.1963131 2.337667 -0.0002075661 0.023898743 1.115 1.115 1.115 0.4 AUTHOR Local refinement map (1/2) of the human PI3KC3-C1 complex (EMD-40669) AlphaFold in silico model AB INITIO MODEL REAL emd_41056_half_map_1.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 401.4 401.4 401.4 90.0 90.0 90.0 X Y Z -0.60082257 1.2334691 0.0003064134 0.054164324 1.115 1.115 1.115 AUTHOR The according half map (1/2) emd_41056_half_map_2.map.gz 1 IMAGE STORED AS FLOATING POINT NUMBER (4 BYTES) 360 360 360 0 0 0 360 360 360 401.4 401.4 401.4 90.0 90.0 90.0 X Y Z -0.60563934 1.4333018 0.0003096288 0.054103687 1.115 1.115 1.115 AUTHOR The according half map (2/2)